BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
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Ibudilast
Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Group: Pharmaceutical. CAS No. 50847-11-5. Pack Sizes: 5 g. Product ID: B0084-329045. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibuprofen
Ibuprofen is an inhibitor of COX-1 and COX-2 with IC50 of 13 μM and 370 μM, respectively. Ibuprofen has been used to treat mild-moderate pain, fever, and inflammation. Group: Pharmaceutical. CAS No. 15687-27-1. Pack Sizes: 500 g. Product ID: B2693-084941. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibuprofen EP Impurity A
Ibuprofen EP Impurity A is an Ibuprofen impurity used in the study of potent noncompetitive interleukin-8 inhibitors. Group: Pharmaceutical. CAS No. 66622-47-7. Pack Sizes: 50 mg. Product ID: B2694-212873. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibuprofen EP Impurity J
Ibuprofen EP Impurity J is an Ibuprofen impurity used in the study of potent noncompetitive interleukin-8 inhibitors. Group: Pharmaceutical. CAS No. 65813-55-0. Pack Sizes: 25 mg. Product ID: B2694-147018. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibuprofen EP Impurity K
Ibuprofen EP Impurity K is a degradation product of Ibuprofen arising from oxidative and thermal treatment. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. Group: Pharmaceutical. CAS No. 43153-07-7. Pack Sizes: 100 mg. Product ID: B2694-212829. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibuprofen EP Impurity L
Ibuprofen EP Impurity L is a degradation product of Ibuprofen, a nonsteroidal anti-inflammatory drug. Group: Pharmaceutical. CAS No. 53949-53-4. Pack Sizes: 25 mg. Product ID: B2694-123429. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibuprofen Impurities
Ibuprofen Impurities, comprising various chemical entities, are pivotal in the quality control and pharmacological evaluation of ibuprofen formulations. These impurities assist researchers in identifying the stability, efficacy, and safety profiles of ibuprofen, a widely used nonsteroidal anti-inflammatory drug (NSAID) for pain management and inflammation reduction. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibuprofen lysine
Ibuprofen lysine is a non-selective COX inhibitor that can be used as an anti-inflammatory drug. Group: Pharmaceutical. CAS No. 57469-77-9. Pack Sizes: 2 g. Product ID: B2693-072008. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibuprofen piconol
Ibuprofen piconol is an anti-inflammatory agent that can be synthesized from Ibuprofen. It acts as a cyclooxygenase inhibitor. Group: Pharmaceutical. CAS No. 64622-45-3. Pack Sizes: 5 g. Product ID: B0046-448719. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ibutilide Impurities
Ibutilide Impurities occupy a cardinal role in the biomedical domain, essential for verifying purity and safety parameters of the anti-arrhythmic agent, Ibutilide. In the drug development continuum, these impurities undergo rigorous scrutiny, enhancing therapeutic efficacy while minimizing potential adversities, thereby refining atrial fibrillation and flutter treatment methodologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
ICA-069673
ICA-069673 is an orally active, potent and selective KCNQ2/Q3 potassium channel activator (IC50= 0.69 μM) with 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5 (EC50s = 14.3 μM). Group: Pharmaceutical. CAS No. 582323-16-8. Pack Sizes: 100 mg. Product ID: B2693-007304. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Icariin
Icariin is a flavonol glycoside and a PDE5 inhibitor (IC50 = 5.9 μM) with 67-fold selectivity for PDE5 over PDE4. It exhibits antioxidant and anticancer activity. At a concentration of 1 x 107 mol/L, Icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes. At 20 μg/ml, Icariin increases the proliferation and differentiation of cultured human osteoblasts. Icariin affects the aging mechanism from different aspects, can delay the aging process and prevent the occurrence of senile diseases. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 489-32-7. Pack Sizes: 5 g. Product ID: NP1908. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Icariside E5
Icariside E5 is a lignan glycoside isolated from the herbs of Epimedium brevicornu. It has antioxidant property that strengthens the importance of peppers in the Mediterranean diet. Uses: Antioxidant property. Group: Pharmaceutical. CAS No. 126176-79-2. Pack Sizes: 1 mg. Product ID: NP4028. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Icariside I
Icariside I is extracted from the herbs of Epimedium brevicornum Maxim. Group: Pharmaceutical. CAS No. 56725-99-6. Pack Sizes: 25 mg. Product ID: B2703-464608. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Icariside II
A regulator of CXCR4 expression. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 113558-15-9. Pack Sizes: 50 mg. Product ID: NP1910. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Icaritin
Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or ti
London
Icatibant Acetate
Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 138614-30-9. Pack Sizes: 10 mg. Product ID: BAT-010084. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Icatibant Impurities
Icatibant Impurities hold a crucial position in biomedical sciences, particularly concerning the advancement and quality assurance of Icatibant, a therapeutic agent for hereditary angioedema. These impurities assist in evaluating drug purity and stability, thereby enhancing safety and efficacy, ultimately fueling progress in therapeutic research and protocol optimization. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
ICEC-0942
ICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 μM). Uses: Anticancer drug. Group: Pharmaceutical. CAS No. 1805833-75-3. Pack Sizes: 10 mg. Product ID: B0084-008621. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Icilin
Icilin is a synthetic CMR1/TRPM8 super agonist in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM) more potently than menthol or low temperatures. Uses: Both heat sensitive (vr1) and cold-sensitive (cmr1 (rat); trpm8 (human)) receptors. Group: Pharmaceutical. CAS No. 36945-98-9. Pack Sizes: 50 mg. Product ID: B0084-113190. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Iclaprim
Iclaprim is a diaminopyrimidine and acts as a dihydrofolate reductase (DHFR) inhibitor active against gram-positive organisms being developed for the treatment of complicated skin and soft tissue infections caused by antibiotic-resistant bacteria. Group: Pharmaceutical. CAS No. 192314-93-5. Pack Sizes: 2 mg. Product ID: B0084-244921. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Icosanal
Icosanal. Group: Pharmaceutical. CAS No. 2400-66-0. Pack Sizes: 100 mg. Product ID: B0001-273983. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Icosanamide
Icosanamide, a derivative of fatty acid, displays promise as a therapeutic agent for diverse inflammatory ailments. With its impressive anti-inflammatory attributes, the compound has garnered attention for handling autoimmune diseases and treating conditions such as rheumatoid arthritis. Its efficacy is well-documented in several clinical studies. Group: Pharmaceutical. CAS No. 51360-63-5. Pack Sizes: 100 mg. Product ID: B0001-274275. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Icotinib
Icotinib Hydrochloride (BPI-2009H), or Icotinib, is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Group: Pharmaceutical. CAS No. 610798-31-7. Pack Sizes: 300 mg. Product ID: B0084-459334. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Icotinib hydrochloride
Icotinib Hydrochloride is a quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), which is upregulated in a variety of cancer cell types. Icotinib supresses the cancer cell proliferation via EGFR tyrosine kinase inhibition. Group: Pharmaceutical. CAS No. 1204313-51-8. Pack Sizes: 300 mg. Product ID: BBF-04036. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
iCRT 14
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling. It is thought to directly influence the interaction between β-catenin and TCF4. It also induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. Group: Pharmaceutical. CAS No. 677331-12-3. Pack Sizes: 25 mg. Product ID: B0084-272145. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Idarubicin Impurities
Idarubicin Impurities hold critical importance in biomedical realms, facilitating the scrutiny and purity assessment of idarubicin, an anthracycline antineoplastic agent employed in oncology. These impurities are essential to quality control in drug synthesis, shedding light on leukemia and other cancer therapeutics, thereby enhancing pharmaceutical precision. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Idarubicinone
Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Group: Pharmaceutical. CAS No. 60660-75-5. Pack Sizes: 5 mg. Product ID: B0709-003996. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Idasanutlin
Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Uses: For research used only. Group: Pharmaceutical. CAS No. 1229705-06-9. Pack Sizes: 200 mg. Product ID: B0084-462568. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Idebenone
Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Idebenone is a smart promoting drug, which is mainly used in the treatment of many degenerative diseases of the central nervous system related to oxidative compressions, such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and cerebral failure, and is also used in the treatment of Friedreich's ataxia. It can also be used in cosmetic formulations to clear free radicals, inhibit lipid peroxidation, inhibit inflammation, inhibit DNA damage, photoprotection, reduce pigmentation, and other cosmetic effects. Group: Pharmaceutical. CAS No. 58186-27-9. Pack Sizes: 10 g. Product ID: NP3168. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Idebenone Impurities
Idebenone Impurities play a critical role in the development and enhancement of pharmaceuticals targeting neurodegenerative diseases like Alzheimer's and muscular dystrophies. They are pivotal in quality control and formulation optimization, ensuring drug efficacy and safety by identifying and minimizing unwanted variations during the manufacturing process. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Idelalisib
Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Group: Pharmaceutical. CAS No. 870281-82-6. Pack Sizes: 250 mg. Product ID: B0084-307712. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Idelalisib Impurities
Idelalisib Impurities are essential for pharmaceutical research and development, offering insights into the stability and efficacy of the drug Idelalisib, used to treat chronic lymphocytic leukemia and follicular lymphoma. Analysis of these impurities aids in improving Idelalisib formulations and ensuring quality control in drug manufacturing processes. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ifenprodil Tartrate
Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM. Uses: Adrenergic alpha-antagonists. Group: Pharmaceutical. CAS No. 23210-58-4. Pack Sizes: 1 g. Product ID: B2693-367328. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ifosfamide
Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer. Uses: Antineoplastic agents, alkylating. Group: Pharmaceutical. CAS No. 3778-73-2. Pack Sizes: 5 g. Product ID: B2693-114093. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ifosfamide Impurities
Ifosfamide Impurities, integral to the pharmaceutical quality control process, assist in assessing the safety and efficacy of ifosfamide, a potent chemotherapeutic agent used in treating various cancers, including testicular cancer and sarcomas. These impurities play a critical role in ensuring drug purity and compliance with regulatory standards. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
IGF-1 LR3
IGF-1 LR3 is a lengthened analogue of human insulin-like growth factor 1 (IGF-1). Group: Pharmaceutical. CAS No. 946870-92-4. Pack Sizes: 5 mg. Product ID: BAT-006251. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Iguratimod
Iguratimod is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. Uses: Anti-inflammation agent. Group: Pharmaceutical. CAS No. 123663-49-0. Pack Sizes: 250 mg. Product ID: B0084-056331. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
IKK 16 hydrochloride
IKK 16 hydrochloride is a potent and selective IκB kinase (IKK) inhibitor with IC50s of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα, respectively. It inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells. Group: Pharmaceutical. CAS No. 1186195-62-9. Pack Sizes: 50 mg. Product ID: B1370-470817. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ilaprazole Impurities
Ilaprazole Impurities hold cardinal importance in the biomedical sector, particularly impacting the quality assurance and improvement of Ilaprazole, a proton pump inhibitor addressing gastroesophageal reflux disease and peptic ulcers. Their crucial role underpins safety and therapeutic efficacy in pharmaceutical manufacturing and essential analytical evaluations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
ILK-IN-1
ILK-IN-1, a ILK inhibitor, has been found to restrain the tumor cell growth through regulating signaling pathways related to oncogenesis and tumor progression. IC50: 0.6 μM. Uses: Ilk-in-1 is a ilk inhibitor that has been found to restrain the tumor cell growth through regulating signaling pathways related to oncogenesis and tumor progression. Group: Pharmaceutical. CAS No. 1333146-24-9. Pack Sizes: 10 mg. Product ID: B2693-474480. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Illudin S
Illudin S is a natural sesquiterpene agent with strong anti-tumour activity. Illudin S inhibits DNA synthesis via an unknown mechanism. Group: Pharmaceutical. CAS No. 1149-99-1. Pack Sizes: 2.5 mg. Product ID: BBF-01877. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Ilomastat
Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor, displaying potential anticancer activity. Ilomastat is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc. Ilomastat inhibits enzymes including thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis. Group: Pharmaceutical. CAS No. 142880-36-2. Pack Sizes: 25 mg. Product ID: B0084-302725. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Iloperidone Impurities
Iloperidone impurities are critical analytical standards employed in the quality control and assessment of Iloperidone, an antipsychotic medication used to treat schizophrenia. Monitoring these impurities ensures drug safety and efficacy while aiding in the development of robust pharmaceutical formulations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib
Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with an IC50 for these effects of approximately 0.1 μM, which is similar to the concentration required for inhibition of PDGFR. Imatinib is an oral chemotherapy agent used to treat cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome. Group: Pharmaceutical. CAS No. 152459-95-5. Pack Sizes: 10 g. Product ID: BBF-05855. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib-[d4]
Imatinib-[d4] is an isotopically labelled analogue of Imatinib. Imatinib is an inhibitor of multiple tyrosine kinases. It is a COVID-19-related research product. Group: Pharmaceutical. CAS No. 1134803-16-9. Pack Sizes: 5 mg. Product ID: BLP-005865. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib EP Impurity D
An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Group: Pharmaceutical. CAS No. 1821122-73-9. Pack Sizes: 100 mg. Product ID: B2694-473167. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib EP Impurity J
An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Group: Pharmaceutical. CAS No. 571186-91-9. Pack Sizes: 10 mg. Product ID: B2694-473158. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib Guanidine Impurity
An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Group: Pharmaceutical. CAS No. 581076-65-5. Pack Sizes: 100 mg. Product ID: B2694-257315. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib Impurities
Imatinib Impurities, comprised of various byproducts from imatinib synthesis, are critical in quality control for pharmaceutical research. These impurities help identify and quantify deviations in the production of imatinib, a drug primarily used to treat chronic myeloid leukemia and gastrointestinal stromal tumors, ensuring its safety and effectiveness. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib Impurity C
an impurity of Imatinib (Gleevec). Group: Pharmaceutical. CAS No. 938082-57-6. Pack Sizes: 10 mg. Product ID: B2694-473162. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib Impurity E
an impurity of Imatinib (Gleevec). Group: Pharmaceutical. CAS No. 1365802-18-1. Pack Sizes: 10 mg. Product ID: B2694-473163. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib Impurity M
An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Group: Pharmaceutical. CAS No. 1407229-73-5. Pack Sizes: 25 mg. Product ID: B2694-104820. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imatinib mesylate
Imatinib (INN), marketed by Novartis as Gleevec (Canada, South Africa and the USA) or Glivec (Australia, Europe and Latin America), and sometimes referred to by its investigational name STI-571, is a tyrosine-kinase inhibitor used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). Group: Pharmaceutical. CAS No. 220127-57-1. Pack Sizes: 10 g. Product ID: NP3279. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Imatinib Related Substance B
An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Group: Pharmaceutical. CAS No. 571186-93-1. Pack Sizes: 5 mg. Product ID: B2694-473161. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imazethapyr Impurities
Imazethapyr Impurities are critical for the analytical characterization of the herbicide imazethapyr. These impurities assist in understanding the pharmacokinetic and toxicological profiles, ensuring the safety and efficacy of formulations used in agricultural applications. Their analysis supports environmental safety studies concerning potential contamination sources and their biological impact. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
IMD 0354
IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κβ pathway. Group: Pharmaceutical. CAS No. 978-62-1. Pack Sizes: 50 mg. Product ID: B2693-383149. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imeglimin hydrochloride
Imeglimin hydrochloride is the first in a new tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. It has been shown to act on the liver, muscle and pancreatic β-cells to uniquely target the key defects of type 2 diabetes. Group: Pharmaceutical. CAS No. 775351-61-6. Pack Sizes: 25 mg. Product ID: B2693-463327. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Imetelstat
Imetelstat sodium, the sodium salt of imetelstat, is a telomerase inhibitor, also a synthetic lipid-conjugated, 13-mer oligonucleotide N3' P5'-thio-phosphoramidate with potential antineoplastic activity. Complementary to the template region of telomerase RNA (hTR), imetelstat acts as a competitive enzyme inhibitor that binds and blocks the active site of the enzyme (a "telomerase template antagonist"), a mechanism of action which differs from that for the antisense oligonucleotide-mediated inhibition of telomerase activity through telomerase mRNA binding. Inhibition of telomerase activity in tumor cells by imetelstat results in telomere shortening, which leads to cell cycle arrest or apoptosis. Group: Pharmaceutical. CAS No. 868169-64-6. Pack Sizes: 1 mg. Product ID: B1370-462541. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imidafenacin Impurities
Imidafenacin Impurities are integral in the biomedical industry for quality control and safety assessment of the drug Imidafenacin, utilized to treat overactive bladder symptoms. These impurities help ensure pharmaceutical standards and drive research into improving the therapeutic efficacy and safety of muscarinic receptor antagonists. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imidapril HCl
Imidapril HCl is an ACE inhibitor used as an antihypertensive drug and for the treatment of chronic heart failure. Group: Pharmaceutical. CAS No. 89396-94-1. Pack Sizes: 50 mg. Product ID: B2693-401715. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imidapril Impurities
Imidapril Impurities are crucial analytical reference standards in the biomedical industry, essential for ensuring the purity and efficacy of Imidapril, an antihypertensive drug. These impurities aid in assessing potential contamination, optimizing pharmacological outcomes, and contributing significantly to cardiovascular disease management strategies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imidazole Impurities
Imidazole Impurities, crucial components in the biomedical realm, function as reference standards pivotal for antihistamine and antifungal drug formulation. Furthermore, these impurities aid in optimizing synthetic methodologies and in the elucidation of side reactions, particularly within pharmaceutical agents such as ketoconazole and cimetidine, enhancing overall drug development quality. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Imidocarb-[d8] dihydrochloride
Labelled Imidocarb 2HCl. Imidocarb 2HCl is a salt form of Imidocarb, which is a derivative of urea used as an antiprotozoal agent in the veterinary drug. Group: Pharmaceutical. Pack Sizes: 25 mg. Product ID: BLP-008861. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imidocarb Impurities
Imidocarb Impurities are crucial in the quality control and safety assessment of imidocarb-based drugs, primarily used in veterinary medicine for treating babesiosis and anaplasmosis. These impurities aid in ensuring the efficacy and purity of the therapeutic agent, thus supporting the development of effective antiparasitic treatments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Iminostilbene Impurities
Iminostilbene Impurities hold a critical role in the biomedical sector, serving as analytical benchmarks for purity assessment in anticonvulsant pharmaceuticals, notably carbamazepine. These impurities facilitate evaluations of drug safety, therapeutic efficacy, and stringent quality control, which are essential components in the production of epilepsy and trigeminal neuralgia treatments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imipenem Impurities
Imipenem Impurities, integral to the pharmaceutical spectrum, facilitate rigorous quality control and validation processes for Imipenem, a potent carbapenem antibiotic combating severe bacterial infections. These impurities are pivotal in safeguarding drug safety and efficacy, reducing adverse effects, and optimizing therapeutic outcomes against multi-resistant pathogens. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imipenem Monohydrate
Imipenem is an intravenous β-lactam antibiotic. It is the first member of the carbapenem class of antibiotics. Imipenem is discovered via a lengthy trial-and-error search for a more stable version of the natural product thienamycin, which is produced by the bacterium Streptomyces cattleya. Imipenem has a broad spectrum of activity against aerobic and anaerobic, Gram-positive and Gram-negative bacteria. It is particularly important for its activity against Pseudomonas aeruginosa and the Enterococcus species, but it is not active against MRSA. Uses: Anti-bacterial agents. Group: Pharmaceutical. CAS No. 74431-23-5. Pack Sizes: 500 mg. Product ID: BBF-04641. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Imiquimod
An agonist of TLR7 with immune response modifying activity, Approved for basal cell carcinoma, In Phase III for VIN and CIN, Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. Uses: An immune response modifier. it stimulates the production of interferon-a. Group: Pharmaceutical. CAS No. 99011-02-6. Pack Sizes: 25 g. Product ID: B2693-080488. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Imiquimod-[d9]
Imiquimod-[d9] is a detuterated Imiquimod. Imiquimod is a medication of the immune response modifier class for the treatment of genital warts, superficial basal cell carcinoma, and actinic keratosis. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: BLP-014125. Molecular formula: Custom synthesis is available. Send your inquiries for more information.