BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Glycine Impurities | Glycine Impurities hold paramount significance within the biopharmaceutical sector, imperative for the development, validation, and purity assessment of glycine-containing pharmaceuticals. Their role in detecting contaminants ensures drug safety and efficacy, crucial for treating metabolic dysfunctions, neurological anomalies, and muscle rehabilitation therapies, thereby fortifying therapeutic precision. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Glycine, N-(1-iminopentyl)- | N-(1-iminopentyl)glycine, a neurotransmitter analog, has demonstrated agonist activity at both the NMDA and glycine receptors, highlighting its unique properties. Promising clinical results in animal models of stroke have suggested its potential as a critical agent in the treatment of cerebral ischemia and its associated symptoms. The complexity of its action, coupled with its potential therapeutic value, make this compound an essential prospect for further investigation and development. Group: Pharmaceutical. CAS No. 193140-43-1. Pack Sizes: 50 mg. Product ID: B2699-172634. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycitein | Glycitein is a soybean (yellow cultivar) isoflavonoid. It may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Uses: The compund shows an anti-cancer activity. Group: Pharmaceutical. CAS No. 40957-83-3. Pack Sizes: 100 mg. Product ID: B2703-465083. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycopyrrolate Bromide | Glycopyrrolate bromide is a muscarinic competitive antagonist used as an antispasmodic. Uses: Adjuvants, anesthesia. Group: Pharmaceutical. CAS No. 596-51-0. Pack Sizes: 1 g. Product ID: B0084-072614. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycopyrrolate Erythro Isomer (RR/SS-Isomer) | Glycopyrrolate Erythro Isomer is one of Glycopyrrolate impurities. Glycopyrrolate is an anticholinergic agent with antispasmodic activity used to treat gastrointestinal conditions associated. Group: Pharmaceutical. Pack Sizes: 1 g. Product ID: B1370-472146. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycopyrrolate Impurities | Glycopyrrolate Impurities, integral to the biomedical sector, facilitate the meticulous assessment of glycopyrrolate purity, a critical medication for peptic ulcers, chronic obstructive pulmonary disease, and hypersalivation management. These impurities underpin drug stability evaluation, thereby safeguarding therapeutic efficacy and ensuring safety in clinical administrations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycopyrronium Bromide EP Impurity I | Glycopyrrolate Impurity I is an impurity of Glycopyrrolate, which is an anticholinergic agent with antispasmodic activity used to treat gastrointestinal conditions associated. Group: Pharmaceutical. CAS No. 1404453-68-4. Pack Sizes: 250 mg. Product ID: B1370-472138. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycosolone | Glycosolone is an alkaloid isolated from Glycosmis pentaphylla. Group: Pharmaceutical. CAS No. 67879-81-6. Pack Sizes: 1 mg. Product ID: NP0121. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycozolinine | Glycozolinine isolated from the herbs of Micromelum sp. Uses: Antibacterial; antimicrobial. Group: Pharmaceutical. CAS No. 5257-8-9. Pack Sizes: 1 mg. Product ID: NP0295. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycyrol | Neoglycyrol is a natural coumarin compound found in the roots of Glycyrrhiza uralensis Fisch. Neoglycyrol exhibits some cardioprotective effects. Uses: Cardioprotective. Group: Pharmaceutical. CAS No. 23013-84-5. Pack Sizes: 10 mg. Product ID: NP1098. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycyrrhetic Acid 3-O-β-D-Glucuronide | Glycyrrhetic Acid 3-O-β-D-Glucuronide, a naturally-occurring compound derived from licorice root extract, boasts a repertoire of anti-inflammatory and antiviral characteristics. Manifesting potential to curb viral infections (such as influenza and hepatitis), it also effectively treats psoriasis and eczema. Group: Pharmaceutical. CAS No. 34096-83-8. Pack Sizes: 10 mg. Product ID: B2705-241827. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycyrrhisoflavone | Glycyrrhisoflavone is a natural flavonoid compound found in several plants. Group: Pharmaceutical. CAS No. 116709-70-7. Pack Sizes: 5 mg. Product ID: NP2004. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glycyrrhizic acid | Glycyrrhizin (Glycyrrhizic Acid) is a widely used anti-inflammatory agent isolated from the licorice root. It has anti-tumor, antiviral ,antiallergic, anti-inflammatory, immunoregulatory,anti-diabetic activities. Glycyrrhizic acid also can be used in cosmetics material. Group: Pharmaceutical. CAS No. 1405-86-3. Pack Sizes: 50 mg. Product ID: NP7010. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gly-Glu-Gly | Behold Gly-Glu-Gly, a tripeptide showing promising efficacy as a natural anti-inflammatory agent in biomedical contexts. Its potential is grounded in studies that have explored its aptitude for mitigating oxidative stress and inflammation in numerous diseases including rheumatoid arthritis, asthma, and cerebral ischemia/reperfusion injury. The full extent of its therapeutic potential, however, remains a topic of ongoing research and investigation. Group: Pharmaceutical. CAS No. 50997-16-5. Pack Sizes: 5 mg. Product ID: BAT-006210. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GlyH-101 | N-2-Naphthalenyl-glycine 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide is a glycine hydrazide that has recently been shown to block CFTR channels. However, its effects on cardiomyocytes are unknown. Studies have demonstrated that GlyH-101 blocks cardiac I Cl.PKA channels in a similar fashion to that reported for recombinant CFTR. Group: Pharmaceutical. CAS No. 328541-79-3. Pack Sizes: 25 mg. Product ID: B0084-430555. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gly-His-Lys | Gly-His-Lys is a tripeptide that can form a complex with copper ions. It is used for hair growth and skin care in cosmetics. It is a liver cell growth factor and stimulates hepatic erythropoietic factor production. It plays an important role in the care process of skin natural aging, such as cell proliferation, inflammation, angiogenesis, pigment formation and protein synthesis and regulation. Peptides are used in cosmetics to promote collagen production, anti-free radical oxidation, anti-inflammatory repair, anti-edema, whitening, breast enhancement and weight loss. It plays an important role in the care process of skin natural aging, such as cell proliferation, inflammation, angiogenesis, pigment formation and protein synthesis and regulation. Peptides are used in cosmetics to promote collagen production, anti-free radical oxidation, anti-inflammatory repair, anti-edema, whitening, breast enhancement and weight loss. Group: Pharmaceutical. CAS No. 49557-75-7. Pack Sizes: 5 g. Product ID: BAT-010755. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GNE-3511 | GNE-3511 has been found to be a DLK, MAP3K12 kinase inhibitor that could probably exhibit protection action of primary neurons. IC50: 0.107 uM (DLK). Group: Pharmaceutical. CAS No. 1496581-76-0. Pack Sizes: 50 mg. Product ID: B0084-475829. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GNE-6776 | GNE-6776 is a potent and non-covalent USP7 inhibitor with IC50 of 1.34 uM. GNE-6776 targets cellular USP7, MDM2, and p53 signalling pathways, and induces tumor cell death. Group: Pharmaceutical. CAS No. 2009273-71-4. Pack Sizes: 5 mg. Product ID: B0084-284761. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GNE-7915 | GNE-7915 is a potent, selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 9 nM. Group: Pharmaceutical. CAS No. 1351761-44-8. Pack Sizes: 100 mg. Product ID: B0084-462278. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GNE-8525 | This active molecular is a selective pan-TRK inhibitor. GNE-8525 shows potent antiproliferation activity (IC50 = 0.003 μM) and it shows in vivo antitumor efficacy in tumor xenograft model derived from the KM12 cell line. TRKA are believed to be the key oncogenic driver in many tumors including glioblastoma, melanoma and so on. Uses: Antitumor. Group: Pharmaceutical. CAS No. 1196546-33-4. Pack Sizes: 50 mg. Product ID: B0084-475140. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gnf179 Impurities | Gnf179 Impurities hold substantial importance in the realm of quality control, integral to the synthesis and production of the antimalarial drug candidate GNF179. This scrutiny aids in safeguarding drug integrity and therapeutic efficacy by elucidating potential influences on the pharmacological characteristics and effectiveness against Plasmodium species responsible for malaria. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GNF 5837 | GNF 5837 is a potent and selective pan-Trk inhibitor that blocks tumor gowth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. GNF 5837 displays antiproliferative effects in cellular Ba/F3 assays with IC50 values of 7, 9 and 11 nM for cells expressing Tel-TrkC, Tel-TrkB and Tel-TrkA respectively. Group: Pharmaceutical. CAS No. 1033769-28-6. Pack Sizes: 50 mg. Product ID: B0084-462361. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GNF-Pf-2328 | GNF-Pf-2328. Group: Pharmaceutical. CAS No. 380455-04-9. Pack Sizes: 5 mg. Product ID: B1370-448041. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Golotimod | Golotimod is an orally bioactive synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and antineoplastic activities. Golotimod has been shown to inhibit the expression of STAT-3, reversing immunosuppression and stimulating an anti-tumor immune response. It may stimulate the production of T-lymphocytes (in particular the helper T [Th1] cells), activate macrophages, and increase levels of interleukin 2 and interferon gamma. Group: Pharmaceutical. CAS No. 229305-39-9. Pack Sizes: 50 mg. Product ID: BAT-010153. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Golvatinib | golvatinib (also known as E7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c-Met and VEGFR-2, which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases. c-Met and VEGFR-2 are upregulated in a variety of various tumor cell types and play important roles in tumor cell growth, migration and angiogenesis. Group: Pharmaceutical. CAS No. 928037-13-2. Pack Sizes: 50 mg. Product ID: B2693-460626. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gomisin A | Schisandrol B is one of its major active constituents of traditional hepato-protective Chinese medicine, Schisandra sphenanthera. Uses: Antineoplastic; anti-inflammatory. Group: Pharmaceutical. CAS No. 58546-54-6. Pack Sizes: 20 mg. Product ID: NP4020. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gomisin D | Gomisin D is an inherent natural compound hailing from herbal medicine, used for studying maladies such as hepatitis. Group: Pharmaceutical. CAS No. 60546-10-3. Pack Sizes: 20 mg. Product ID: NP3942. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gomisin G | Gomisin G exhibited the most potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300. Uses: Anti-hiv. Group: Pharmaceutical. CAS No. 62956-48-3. Pack Sizes: 10 mg. Product ID: NP4123. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gomisin J | Gomisin J inhibits LPO in rat liver mitochondria and protects cultured myocardial cells from being injured by calcium paradox. Group: Pharmaceutical. CAS No. 66280-25-9. Pack Sizes: 20 mg. Product ID: NP3927. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (-)Gomisin L1 | (-)Gomisin L1 is an enigmatic natural compound sourced from Schisandra chinensis illuminating its remarkable attributes as a potent modulator in the research of inflammation, cancer, Alzheimer's disease and cardiovascular disorders. Group: Pharmaceutical. CAS No. 82425-43-2. Pack Sizes: 2 mg. Product ID: NP4049. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (+)Gomisin M2 | (+)Gomisin M2 is a lignan isolated and purified form fruits of Schizandra chinensis which is is utilized for antitussive and tonic purposes in Oriental medicine. Group: Pharmaceutical. CAS No. 82425-45-4. Pack Sizes: 5 mg. Product ID: NP3934. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GOMISIN N | Gomisin N produced beneficial sedative and hypnotic bioactivity, which might be mediated by the modification of the serotonergic and GABAergic system. Uses: Anticancer, anti-hepatotoxic, anti-oxidative and anti-inflammatory. Group: Pharmaceutical. CAS No. 69176-52-9. Pack Sizes: 20 mg. Product ID: NP3918. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gossypetin | Gossypetin is a flavonol compound isolated from the flowers and the calyx of Hibiscus sabdariffa (roselle). It has been shown to exhibit antibacterial activity and act as a TrkB antagonist. Group: Pharmaceutical. CAS No. 489-35-0. Pack Sizes: 100 mg. Product ID: B0005-023593. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gossypin | Gossypin is a pentahydroxyflavone glucoside isolated from Hibiscus vitifolius. Gossypin exhibits antioxidant, antiinflammatory, anticancer and antidiabetic activities. Group: Pharmaceutical. CAS No. 652-78-8. Pack Sizes: 250 mg. Product ID: B1370-130853. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gossypol Acetic Acid | Gossypol Acetic Acid is a phenol compound from plants of the Gossypium genus, Malvaceae. It binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. It exhibits antiviral activity at low concentration. Uses: Spermatocidal agents. Group: Pharmaceutical. CAS No. 12542-36-8. Pack Sizes: 5 g. Product ID: B2703-056498. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GPRP acetate | GPRP acetate, a fibrinogen-related peptide, inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). Group: Pharmaceutical. CAS No. 157009-81-9. Pack Sizes: 100 mg. Product ID: BAT-009226. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GR 64349 | GR 64349 is a potent and selective agonist of tachykinin NK2 receptor (EC50 = 3.7 nM in rat colon). Group: Pharmaceutical. CAS No. 137593-52-3. Pack Sizes: 1 mg. Product ID: BAT-010280. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gramicidin S | Gramicidin S is an antibiotic produced by the strain of Bacillus brevis. It is effective against some gram-positive and gram-negative bacteria as well as some fungi. Uses: For research use only. Group: Pharmaceutical. CAS No. 113-73-5. Pack Sizes: 10 mg. Product ID: BAT-010152. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Grandiflorenic acid | Grandiflorenic acid (GA) is a natural diterpenoid found in the herbs of Siegesbeckia orientalis L. Grandiflorenic acid shows the uterine responses induced by ZACE. Group: Pharmaceutical. CAS No. 22338-67-6. Pack Sizes: 1 mg. Product ID: NP1636. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Grandifloric acid | Grandifloric acid is a natural diterpenoid found in the herbs of Siegesbeckia orientalis L. Group: Pharmaceutical. CAS No. 22338-69-8. Pack Sizes: 1 mg. Product ID: NP1689. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Granisetron | Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medull. Uses: Granisetron is an antagonist of serptpmom 5-ht3 receptor and could be used to relieve the nausea and vomiting symptom after receving chemotherapy by decreasing the activity of the vagus nerve. Group: Pharmaceutical. CAS No. 109889-09-0. Pack Sizes: 1 g. Product ID: B0084-474340. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Granisetron Impurities | Granisetron Impurities, integral to pharmaceutical quality assurance, are paramount in refining and evaluating granisetron formulations. These impurities are assessed rigorously given granisetron's pivotal antiemetic role in alleviating chemotherapy and radiation-induced nausea. Meticulous impurity control ensures the therapeutic safety and efficacy, thereby sustaining drug reliability within oncological treatments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Grapiprant (CJ-023423) | Grapiprant, also known as CJ-023,423, RQ-00000007 and AAT-007, is a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. Group: Pharmaceutical. CAS No. 415903-37-6. Pack Sizes: 10 mg. Product ID: B0084-470919. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Grasshopper ketone | Grasshopper Ketone is a natural compound widely used in the research of ailments like Alzheimer's and Parkinson's disease. Group: Pharmaceutical. CAS No. 41703-38-2. Pack Sizes: 1 mg. Product ID: NP6030. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Graveoline | Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. Group: Pharmaceutical. CAS No. 485-61-0. Pack Sizes: 200 mg. Product ID: B2696-119203. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GRGDS | GRGDS is a synthetic integrin antagonist. Group: Pharmaceutical. CAS No. 96426-21-0. Pack Sizes: 50 mg. Product ID: BAT-010197. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GRGDSP | GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor which can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization. Group: Pharmaceutical. CAS No. 91037-75-1. Pack Sizes: 10 mg. Product ID: BAT-010499. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Griffipavixanthone | Griffipavixanthone is a natural xanthone found in the fruits of Garcinia oblongifolia Champ, it inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, with IC50 values of 3.03 ± 0.21 μM at 48h, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS production; which demonstrates that the potential application of griffipavixanthone as an anti-non-small cell lung cancer agent. Uses: Anti-non-small cancer. Group: Pharmaceutical. CAS No. 219649-95-3. Pack Sizes: 1 mg. Product ID: NP7252. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Griffithazanone A | Griffithazanone A is an alkaloid compound found in herbs of Goniothalamus yunnanensis. Group: Pharmaceutical. CAS No. 240122-30-9. Pack Sizes: 2 mg. Product ID: NP0149. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Grifolic acid | Grifolic Acid is a selective partial GPR120 agonist. It induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40. Group: Pharmaceutical. CAS No. 80557-12-6. Pack Sizes: 1 mg. Product ID: NP4634. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Griseofulvin | It is produced by the strain of Penicillum griseofulvum. It can inhibit the strains of ClassZygomycetes, Ascomycetes and Deuteromycetes (MIC is 1-20 μg/mL), It can also inhibit the crimping of the spore tube of garlic rot grape (MIC is 1 μg/mL). It has obvious inhibitory effect on metaphase mitosis of bone marrow, small intestine and Walker 256 cancer cells. Group: Pharmaceutical. CAS No. 126-07-8. Pack Sizes: 50 g. Product ID: BBF-01806. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Griseofulvin Impurities | Griseofulvin Impurities serve as reference standards in the quality control of Griseofulvin, an antifungal medication used to treat skin and nail infections. These impurities are crucial for ensuring the purity, safety, and efficacy of the drug, thereby supporting pharmaceutical development and regulatory compliance. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Groenlandicine | Groenlandicine, a botanical-derived constituent, exhibits profound implications for biomedical applications of studying an array of afflictions, encompassing neoplastic disorders and cardiovascular impairments. Group: Pharmaceutical. CAS No. 38691-95-1. Pack Sizes: 2.5 mg. Product ID: B2703-465676. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Grossamide | Cis-Grossamide K is a natural alkaloid found in the herbs of Cannabis sativa L. Cis-Grossamide K exhibits a strong anti-melanogenic activity on the cells without high cell toxicity. Uses: Anti-melanogenic. Group: Pharmaceutical. CAS No. 80510-06-1. Pack Sizes: 1 mg. Product ID: NP0387. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Grosvenorine | Grosvenorine is extracted from roots of the fruits of Siraitia grosuenorii. It has free radical scavenging activity. Group: Pharmaceutical. CAS No. 156980-60-8. Pack Sizes: 10 mg. Product ID: B0005-465744. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GRP (porcine) | GRP (porcine) is a mammalian bombesin-like peptide neurotransmitter that acts as an agonist for the gastrin-releasing peptide receptor (GRPR). It was shown to activate GABAergic interneurons in the amygdala resulting in an increase in GABA release and fear suppression in mice in vivo. Group: Pharmaceutical. CAS No. 74815-57-9. Pack Sizes: 10 mg. Product ID: B2693-032077. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GS-441524 | GS-441524 is an analog nucleotide inhibitor against feline infectious peritonitis virus (FIPV). EC50 is 0.78?uM. GS-441524 is also a metabolite and intermediate of Remdesivir. Group: Pharmaceutical. CAS No. 1191237-69-0. Pack Sizes: 5 g. Product ID: B2693-012542. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GS967 | GS967, also known as GS-458967, is a highly selective late sodium channel current blocker. The selective inhibition of late INa with GS967 can exert antiarrhythmic effects by suppressing EAD- and DAD-mediated extrasystolic activity in PFs and PV and SVC sleeve preparations. Group: Pharmaceutical. CAS No. 1262618-39-2. Pack Sizes: 200 mg. Product ID: B0084-470831. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK1016790A | GSK1016790A is a novel and potent transient receptor potential vanilloid 4 (TRPV4) agonist. It has been used to demonstrate a role for TRPV4 in regulating urinary bladder activity and endothelial control of vascular tone. It elicited Ca2+ influx in mouse and human TRPV4 expressing HEK cells with EC50 values of 18 and 2.1 nM, respectively. It also evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM, which is 300 fold more potent than 4a-PDD. It was developed by GlaxoSmithKline. Uses: Gsk1016790a regulats urinary bladder activity and endothelial control of vascular tone. Group: Pharmaceutical. CAS No. 942206-85-1. Pack Sizes: 100 mg. Product ID: B0084-382782. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK1059615 | GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. Group: Pharmaceutical. CAS No. 958852-01-2. Pack Sizes: 50 mg. Product ID: B0084-272127. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK1324726A | GSK1324726A is a novel, potent and selective small molecule inhibitor of BET proteins with high affinity to BRD2 (IC50 = 41 nM), BRD3 (IC50 = 31 nM), and BRD4 (IC50 = 22 nM). Group: Pharmaceutical. CAS No. 1300031-52-0. Pack Sizes: 100 mg. Product ID: B1370-463391. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK 189254A | GSK-189,254 is a H3 histamine receptor inverse agonist. It has subnanomolar affinity for the H3 receptor with Ki of 0.2nM. It possesses stimulant and nootropic effects and analgesic action suggesting a role for H3 receptors in pain processing in the spinal cord. No development was reported about Phase-II clinical trials for Narcolepsy in Europe. Uses: Narcolepsy. Group: Pharmaceutical. CAS No. 720690-73-3. Pack Sizes: 300 mg. Product ID: B0084-459482. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-2018682 | GSK-2018682 is a potent and selective agonist of sphingosine-1-phosphate receptor (S1PR) subtype 1 that has the potential to treat multiple sclerosis (MS). Group: Pharmaceutical. CAS No. 1034688-30-6. Pack Sizes: 10 mg. Product ID: B0084-008117. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK2193874 | GSK2193874 is a potent, orally active and specific antagonist of TRPV4 ion channels (IC50 values 2 and 40 nM for rat and human receptors, respectively). GSK2193874 is selective over a panel of ~200 human receptors, channels and enzymes. Group: Pharmaceutical. CAS No. 1336960-13-4. Pack Sizes: 20 mg. Product ID: B0084-007718. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-2256098 | GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. Group: Pharmaceutical. CAS No. 1224887-10-8. Pack Sizes: 100 mg. Product ID: B0084-470953. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK 2606414 | GSK 2606414 is a potent and selective PERK inhibitor that suppresses PERK activation in cells and inhibits the growth of a human tumor xenograft in mice. Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states. Evidence that PERK is implicated in tumorigenesis and cancer cell survival stimulated our search for small-molecule inhibitors. Group: Pharmaceutical. CAS No. 1337531-36-8. Pack Sizes: 100 mg. Product ID: B0084-462365. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-2881078 | GSK-2881078, an indole derivative, has been found to be an androgen receptor modulator that could probably be effective against Cachexia. It is still under Phase I trail. Uses: Anabolic agents. Group: Pharmaceutical. CAS No. 1539314-06-1. Pack Sizes: 25 mg. Product ID: B2693-475855. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK2982772 | GSK2982772, with potential effect to treat inflammatory diseases, potently binds to RIP1 with exquisite kinase specificity. In phase 2a clinical studies for psoriasis, rheumatoid arthritis, and ulcerative colitis. Group: Pharmaceutical. CAS No. 1622848-92-3. Pack Sizes: 100 mg. Product ID: B0084-007719. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK3326595 | GSK3326595, also called as EPZ015938, is an orally available and specific inhibitor of protein arginine methyltransferase 5 (PRMT5) that potently inhibits tumor growth in vitro and in vivo in animal models and has entered clinical trials for the treatment of solid tumors and non-Hodgkin's lymphoma. Group: Pharmaceutical. CAS No. 1616392-22-3. Pack Sizes: 100 mg. Product ID: B2693-007330. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-3787 | GSK-3787 is a potent and selective ligand for PPARdelta with good pharmacokinetic properties. Group: Pharmaceutical. CAS No. 188591-46-0. Pack Sizes: 50 mg. Product ID: B0084-272130. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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