BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Glycoursodeoxycholic acid | Glycoursodeoxycholic Acid is a metabolite of Ursodeoxycholic Acid. Ursodeoxycholic Acid is one of metabolites of intestinal bacteria. Ursodeoxycholic Acid shows an effect of apoptosis suppression and reduction in gallstone formation. Group: Pharmaceutical. Alternative Names: Ursodeoxycholylglycine; GUDCA; Glycine ursodeoxycholic acid; N-(3alpha,7beta-dihydroxy-5beta-cholan-24-oyl)-glycine; N-[(3α,5β,7β)-3,7-dihydroxy-24-oxocholan-24-yl]-glycine. CAS No. 64480-66-6. Pack Sizes: 1mg;1g;10g. Product ID: NP6055. Molecular formula: C26H43NO5. Mole weight: 449.63. Custom synthesis is available. Send your inquiries for more information. |  London |
| Glycozolinine | Glycozolinine isolated from the herbs of Micromelum sp. Uses: Antibacterial; antimicrobial. Group: Pharmaceutical. Alternative Names: 6-Methyl-9H-carbazol-3-ol; Glycozolinol. CAS No. 5257-8-9. Pack Sizes: 1 mg. Product ID: NP0295. Molecular formula: C13H11NO. Mole weight: 197.2. Custom synthesis is available. Send your inquiries for more information. | London |
| Glycyrol | Neoglycyrol is a natural coumarin compound found in the roots of Glycyrrhiza uralensis Fisch. Neoglycyrol exhibits some cardioprotective effects. Uses: Cardioprotective. Group: Pharmaceutical. Alternative Names: 6H-Benzofuro[3,2-c][1]benzopyran-6-one, 3,9-dihydroxy-1-methoxy-2-(3-methyl-2-butenyl)- (9CI); 3,9-Dihydroxy-1-methoxy-2-(3-methyl-2-buten-1-yl)-6H-benzofuro[3,2-c][1]benzopyran-6-one. CAS No. 23013-84-5. Pack Sizes: 10 mg. Product ID: NP1098. Molecular formula: C21H18O6. Mole weight: 366.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Glycyrrhetic Acid 3-O-β-D-Glucuronide | Glycyrrhetic Acid 3-O-β-D-Glucuronide, a naturally-occurring compound derived from licorice root extract, boasts a repertoire of anti-inflammatory and antiviral characteristics. Manifesting potential to curb viral infections (such as influenza and hepatitis), it also effectively treats psoriasis and eczema. Group: Pharmaceutical. Alternative Names: Glycyrrhetic acid 3-O-glucuronide. CAS No. 34096-83-8. Pack Sizes: 10 mg. Product ID: B2705-241827. Molecular formula: C36H54O10. Mole weight: 646.81. Custom synthesis is available. Send your inquiries for more information. | London |
| Glycyrrhisoflavone | Glycyrrhisoflavone is a natural flavonoid compound found in several plants. Group: Pharmaceutical. Alternative Names: 3-[3,4-Dihydroxy-5-(3-methyl-2-butenyl)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one. CAS No. 116709-70-7. Pack Sizes: 5 mg. Product ID: NP2004. Molecular formula: C20H18O6. Mole weight: 354.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Glycyrrhizic acid | Glycyrrhizin (Glycyrrhizic Acid) is a widely used anti-inflammatory agent isolated from the licorice root. It has anti-tumor, antiviral, antiallergic, anti-inflammatory, immunoregulatory, anti-diabetic activities. Glycyrrhizic acid also can be used in cosmetic material. Group: Pharmaceutical. Alternative Names: Glycyrrhizic acid;glycyrrhizin;1405-86-3;Glycyron;Glycyrrhizinic acid;Glycyrrhetinic acid glycoside;potenlini;Glizigen;glycyrrhizate;glyzyrrhizin;18-beta-Glycyrrhizic acid;beta-Glycyrrhizin;18beta-Glycyrrhizic acid;Glycyrrizin;Rizinsan K2 A2 (free acid);HSDB 496;CHEBI:15939;EINECS 215-785-7;Glycyrrhizin [JAN];Liquorice.beta.-glycyrrhizin;NSC 167409;NSC 234419;NSC-167409;NSC-234419;UNII-6FO62043WK. CAS No. 1405-86-3. Pack Sizes: 50 mg. Product ID: NP7010. Molecular formula: C42H62O16. Mole weight: 822.93. Custom synthesis is available. Send your inquiries for more information. | London |
| Gly-Glu-Gly | Behold Gly-Glu-Gly, a tripeptide showing promising efficacy as a natural anti-inflammatory agent in biomedical contexts. Its potential is grounded in studies that have explored its aptitude for mitigating oxidative stress and inflammation in numerous diseases including rheumatoid arthritis, asthma, and cerebral ischemia/reperfusion injury. The full extent of its therapeutic potential, however, remains a topic of ongoing research and investigation. Group: Pharmaceutical. Alternative Names: Gly-Glu-Gly; H-GLY-GLU-GLY-OH; glycylglutamylglycine. CAS No. 50997-16-5. Pack Sizes: 5 mg. Product ID: BAT-006210. Molecular formula: C9H15N3O6. Mole weight: 261.23. Custom synthesis is available. Send your inquiries for more information. | London |
| GlyH-101 | N-2-Naphthalenyl-glycine 2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide is a glycine hydrazide that has recently been shown to block CFTR channels. However, its effects on cardiomyocytes are unknown. Studies have demonstrated that GlyH-101 blocks cardiac I Cl.PKA channels in a similar fashion to that reported for recombinant CFTR. Group: Pharmaceutical. Alternative Names: GlyH 101; GlyH101. CAS No. 328541-79-3. Pack Sizes: 25 mg. Product ID: B0084-430555. Molecular formula: C19H15Br2N3O3. Mole weight: 493.15. Custom synthesis is available. Send your inquiries for more information. | London |
| Gly-His-Lys | Gly-His-Lys is a tripeptide that can form a complex with copper ions. It is used for hair growth and skin care in cosmetics. It is a liver cell growth factor and stimulates hepatic erythropoietic factor production. It plays an important role in the care process of skin natural aging, such as cell proliferation, inflammation, angiogenesis, pigment formation and protein synthesis and regulation. Peptides are used in cosmetics to promote collagen production, anti-free radical oxidation, anti-inflammatory repair, anti-edema, whitening, breast enhancement and weight loss. It plays an important role in the care process of skin natural aging, such as cell proliferation, inflammation, angiogenesis, pigment formation and protein synthesis and regulation. Peptides are used in cosmetics to promote collagen production, anti-free radical oxidation, anti-inflammatory repair, anti-edema, whitening, breast enhancement and weight loss. Group: Pharmaceutical. Alternative Names: L-Lysine, glycyl-L-histidyl-; L-Lysine, N2-(N-glycyl-L-histidyl)-; Glycyl-L-histidyl-L-lysine; GHK; GHK Tripeptide; Growth-modulating peptide; Growth-modulating peptide (human); Kollaren; Kollaren BG; Liver cell growth factor; Liver growth factor; NSC 379527; Prezatide; Tripeptide 1. CAS No. 49557-75-7. Pack Sizes: 5 g. Product ID: BAT-010755. Molecular formula: C14H24N6O4. Mole weight: 340.38. Custom synthesis is available. Send your inquiries for more information. | London |
| GNE-3511 | GNE-3511 has been found to be a DLK, MAP3K12 kinase inhibitor that could probably exhibit protection action of primary neurons. IC50: 0.107 uM (DLK). Group: Pharmaceutical. Alternative Names: GNE-3511; GNE 3511; GNE3511. CHEMBL3393333; SCHEMBL15602439; BDBM50059190; 2-[[6-(3,3-difluoropyrrolidin-1-yl)-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile. CAS No. 1496581-76-0. Pack Sizes: 50 mg. Product ID: B0084-475829. Molecular formula: C23H26F2N6O. Mole weight: 440.5. Custom synthesis is available. Send your inquiries for more information. | London |
| GNE-6776 | GNE-6776 is a potent and non-covalent USP7 inhibitor with IC50 of 1.34 uM. GNE-6776 targets cellular USP7, MDM2, and p53 signalling pathways, and induces tumor cell death. Group: Pharmaceutical. Alternative Names: GNE 6776; GNE-6776; GNE6776; 5-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridyl]-N-methyl-pyridine-2-carboxamide. CAS No. 2009273-71-4. Pack Sizes: 5 mg. Product ID: B0084-284761. Molecular formula: C20H20N4O2. Mole weight: 348.406. Custom synthesis is available. Send your inquiries for more information. | London |
| GNE-7915 | GNE-7915 is a potent, selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 9 nM. Group: Pharmaceutical. Alternative Names: GNE7915; GNE 7915; GNE-7915. CAS No. 1351761-44-8. Pack Sizes: 100 mg. Product ID: B0084-462278. Molecular formula: C19H21F4N5O3. Mole weight: 443.403. Custom synthesis is available. Send your inquiries for more information. | London |
| GNE-8525 | This active molecular is a selective pan-TRK inhibitor. GNE-8525 shows potent antiproliferation activity (IC50 = 0.003 μM) and it shows in vivo antitumor efficacy in tumor xenograft model derived from the KM12 cell line. TRKA are believed to be the key oncogenic driver in many tumors including glioblastoma, melanoma and so on. Uses: Antitumor. Group: Pharmaceutical. Alternative Names: GNF-8625; GNF 8625; GNF8625. (R)-1-(6-(6-(2-(3-fluorophenyl)pyrrolidin-1-yl)imidazo[1,2-b]pyridazin-3-yl)-[2,4'-bipyridin]-2'-yl)piperidin-4-ol. CAS No. 1196546-33-4. Pack Sizes: 50 mg. Product ID: B0084-475140. Molecular formula: C31H30FN7O. Mole weight: 535.63. Custom synthesis is available. Send your inquiries for more information. | London |
| GNF 5837 | GNF 5837 is a potent and selective pan-Trk inhibitor that blocks tumor gowth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. GNF 5837 displays antiproliferative effects in cellular Ba/F3 assays with IC50 values of 7, 9 and 11 nM for cells expressing Tel-TrkC, Tel-TrkB and Tel-TrkA respectively. Group: Pharmaceutical. Alternative Names: GNF5837; GNF-5837; GNF 5837. 1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea. CAS No. 1033769-28-6. Pack Sizes: 50 mg. Product ID: B0084-462361. Molecular formula: C28H21F4N5O2. Mole weight: 535.503. Custom synthesis is available. Send your inquiries for more information. | London |
| GNF-Pf-2328 | GNF-Pf-2328. Group: Pharmaceutical. Alternative Names: BMH-15; BMH 15; BMH15; 5-{[3-(dimethylamino)propyl]amino}-9,10-dimethyl-8H-thieno[2',3':4,5]pyrimido[2,1-a]phthalazin-8-one. CAS No. 380455-04-9. Pack Sizes: 5 mg. Product ID: B1370-448041. Molecular formula: C20H23N5OS. Mole weight: 381.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Golgicide A | Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1. Golgicide A inhibited HSV-1 entry via beta-galactosidase reporter assay and impaired incoming virus transport to the nuclear periphery. Group: Pharmaceutical. Alternative Names: GCA; (3aR,9bS)-rel-6,8-Difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-3H-cyclopenta[c]quinoline; 3H-Cyclopenta[c]quinoline, 6,8-difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-, (3aR,9bS)-. CAS No. 1139889-93-2. Pack Sizes: 100 mg. Product ID: B1370-261662. Molecular formula: C17H14F2N2. Mole weight: 284.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Golotimod | Golotimod is an orally bioactive synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and antineoplastic activities. Golotimod has been shown to inhibit the expression of STAT-3, reversing immunosuppression and stimulating an anti-tumor immune response. It may stimulate the production of T-lymphocytes (in particular the helper T [Th1] cells), activate macrophages, and increase levels of interleukin 2 and interferon gamma. Group: Pharmaceutical. Alternative Names: SCV-07; Gamma-D-Glu-L-trp; SCV07; SCV 07; Gamma-D-Glutamyl-L-tryptophan; (2R)-2-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid. CAS No. 229305-39-9. Pack Sizes: 50 mg. Product ID: BAT-010153. Molecular formula: C16H19N3O5. Mole weight: 333.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Golvatinib | golvatinib (also known as E7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c-Met and VEGFR-2, which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases. c-Met and VEGFR-2 are upregulated in a variety of various tumor cell types and play important roles in tumor cell growth, migration and angiogenesis. Group: Pharmaceutical. Alternative Names: E7050; E-7050; E 7050; Golvatinib. CAS No. 928037-13-2. Pack Sizes: 50 mg. Product ID: B2693-460626. Molecular formula: C33H37F2N7O4. Mole weight: 633.701. Custom synthesis is available. Send your inquiries for more information. | London |
| Gomisin A | Schisandrol B is one of its major active constituents of traditional hepato-protective Chinese medicine, Schisandra sphenanthera. Uses: Antineoplastic; anti-inflammatory. Group: Pharmaceutical. Alternative Names: Gomisin-A; Besigomsin; TJN-101; Wuweizi alcohol-B; Wuweizichun-B. CAS No. 58546-54-6. Pack Sizes: 20 mg. Product ID: NP4020. Molecular formula: C23H28O7. Mole weight: 416.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Gomisin D | Gomisin D is an inherent natural compound hailing from herbal medicine, used for studying maladies such as hepatitis. Group: Pharmaceutical. Alternative Names: 5,13-(Epoxybutanoxy)benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-18-one,5,6,7,8-tetrahydro-6,17-dihydroxy-1,2,3-trimethoxy-6,7,16,17-tetramethyl-,(5S,6S,7S,13aR,16R,17R)-;(11S,12R,15S,24S,25S)-12,25-Dihydroxy-18,19,20-trimethoxy-11,12,24,25-tetramethyl-4,6,9,14-tetraoxapentacyclo[13.7.3.0sup3,7sup.0sup8,22sup.0sup16,21sup]pentacosa-1(22),2,7,16,18,20-hexaen-13-one;7,19-dihydroxy-12,13,14-trimethoxy-6,7,18,19-tetramethyl-6,7-dihydro-5H-10,15-propano[1,3]dioxolo[4',5':5,6]benzo[1,2-g]benzo[i][1,6]dioxacycloundecin-8(10H)-one. CAS No. 60546-10-3. Pack Sizes: 20 mg. Product ID: NP3942. Molecular formula: C28H34O10. Mole weight: 530.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Gomisin G | Gomisin G exhibited the most potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300. Uses: Anti-hiv. Group: Pharmaceutical. Alternative Names: Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-7,8-. CAS No. 62956-48-3. Pack Sizes: 10 mg. Product ID: NP4123. Molecular formula: C30H32O9. Mole weight: 536.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Gomisin J | Gomisin J inhibits LPO in rat liver mitochondria and protects cultured myocardial cells from being injured by calcium paradox. Group: Pharmaceutical. Alternative Names: (6R,7S)-1,2,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulene-3,10-diol. CAS No. 66280-25-9. Pack Sizes: 20 mg. Product ID: NP3927. Molecular formula: C22H28O6. Mole weight: 388.45. Custom synthesis is available. Send your inquiries for more information. | London |
| (-)Gomisin L1 | (-)Gomisin L1 is an enigmatic natural compound sourced from Schisandra chinensis illuminating its remarkable attributes as a potent modulator in the research of inflammation, cancer, Alzheimer's disease and cardiovascular disorders. Group: Pharmaceutical. Alternative Names: (-)-Gomisin L1; Gomisin L1; 82425-43-2; UNII-6HN2PJ55D76HN2PJ55D7. CAS No. 82425-43-2. Pack Sizes: 2 mg. Product ID: NP4049. Molecular formula: C22H26O6. Mole weight: 386.444. Custom synthesis is available. Send your inquiries for more information. | London |
| Gomisin M1 | R(+)-Gomisin M1 can be found in the fruits of Schizandra chinensis. Group: Pharmaceutical. Alternative Names: R(+)-Gomisin M1;Gomisin M1;82467-50-3;(-)Gomisin L1;Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-1-ol, 5,6,7,8-tetrahydro-2, 3,13-trimethoxy-6,7-dimethyl-, stereoisomer;DTXSID601318545;HY-N1529;AKOS040762632;DA-48556;CS-0017078;B0005-188529;B0005-465629;4,5,19-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.0(2),?.0(1)?,(1)?]nonadeca-1(12),2(7),3,5,13,18-hexaen-3-ol;4,5,19-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-3-ol. CAS No. 82467-50-3. Pack Sizes: 1 mg. Product ID: NP3959. Molecular formula: C24H28O12. Mole weight: 508.5. Custom synthesis is available. Send your inquiries for more information. | London |
| (+)Gomisin M2 | (+)Gomisin M2 is a lignan isolated and purified form fruits of Schizandra chinensis which is is utilized for antitussive and tonic purposes in Oriental medicine. Group: Pharmaceutical. Alternative Names: Benzo[3,?4]?cycloocta[1,?2-f]?[1,?3]?benzodioxol-13-ol, 5,?6,?7,?8-tetrahydro-1,?2,?3-trimethoxy-6,?7-dimethyl-, (6S,?7R,?13aR)?-; Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-13-ol, 5,6,7,8-tetrahydro-1,2,3-trimethoxy-6,7-dimethyl-, stereoisomer; (6S,7R,13aR)-5,6,7,8-Tetrahydro-1,2,3-trimethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-13-ol; Gomisin M2. CAS No. 82425-45-4. Pack Sizes: 5 mg. Product ID: NP3934. Molecular formula: C22H26O6. Mole weight: 386.44. Custom synthesis is available. Send your inquiries for more information. | London |
| GOMISIN N | Gomisin N produced beneficial sedative and hypnotic bioactivity, which might be mediated by the modification of the serotonergic and GABAergic system. Uses: Anticancer, anti-hepatotoxic, anti-oxidative and anti-inflammatory. Group: Pharmaceutical. Alternative Names: GOMISIN N; Benzo(3,4)cycloocta(1,2-F)(1,3)benzodioxole, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6R,7S,13as)-. CAS No. 69176-52-9. Pack Sizes: 20 mg. Product ID: NP3918. Molecular formula: C23H28O6. Mole weight: 400.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Goralatide acetate | Goralatide is a physiological regulator of hematopoiesis and inhibits the entry into the S-phase of murine and human hematopoietic stem cells. Ac-SDKP is a physiological substrate of angiotensin I- converting enzyme (ACE). Group: Pharmaceutical. Alternative Names: N-acetyl-Ser-Asp-Lys-Pro; Acetyl-serinyl-aspartyl-lysinyl-proline acetate. Pack Sizes: 25 mg. Product ID: B1370-458984. Molecular formula: C22H37N5O11. Mole weight: 547.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Gossypetin | Gossypetin is a flavonol compound isolated from the flowers and the calyx of Hibiscus sabdariffa (roselle). It has been shown to exhibit antibacterial activity and act as a TrkB antagonist. Group: Pharmaceutical. Alternative Names: Articulatidin; Equisporol; 3,5,7,8,3',4'-Hexahydroxyflavone; 2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxychromen-4-one. CAS No. 489-35-0. Pack Sizes: 100 mg. Product ID: B0005-023593. Molecular formula: C15H10O8. Mole weight: 318.237. Custom synthesis is available. Send your inquiries for more information. | London |
| Gossypin | Gossypin is a pentahydroxyflavone glucoside isolated from Hibiscus vitifolius. Gossypin exhibits antioxidant, antiinflammatory, anticancer and antidiabetic activities. Group: Pharmaceutical. Alternative Names: 3,3,4,5,7,8-Hexahydroxy flavone-8-glucoside; Gossypetin 8-glucoside. CAS No. 652-78-8. Pack Sizes: 250 mg. Product ID: B1370-130853. Molecular formula: C21H20O13. Mole weight: 480.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Gossypol Acetic Acid | Gossypol Acetic Acid is a phenol compound from plants of the Gossypium genus, Malvaceae. It binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. It exhibits antiviral activity at low concentration. Uses: Spermatocidal agents. Group: Pharmaceutical. Alternative Names: Gossypol acetate; Acetate gossypol. CAS No. 12542-36-8. Pack Sizes: 5 g. Product ID: B2703-056498. Molecular formula: C32H34O10. Mole weight: 578.61. Custom synthesis is available. Send your inquiries for more information. | London |
| GP2-114 | GP2-114, a long-acting, highly potent catecholamine, produces current-dependent cardiovascular action when administered by transdermal iontophoresis. Group: Pharmaceutical. Alternative Names: 4-[3-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]butyl]benzamide; 1-(3,4-dihydroxyphenyl)-2-(3-(4-carbamylphenyl)-1-methylpropylamino)ethanol; GP 114; GP 2-114; GP 2-128; GP 2-128 (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1); GP 2-128 monoacetate; GP-114; GP-2-114; GP-2-128. CAS No. 130783-39-0. Pack Sizes: 1mg;1g;10g. Product ID: 130783-39-0. Molecular formula: C19H24N2O4. Mole weight: 344.4. Custom synthesis is available. Send your inquiries for more information. | London |
| GPRP acetate | GPRP acetate, a fibrinogen-related peptide, inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). Group: Pharmaceutical. Alternative Names: Pefa 6003; Pefabloc FG; GPRP.CH3CO2H; glycyl-L-prolyl-L-arginyl-L-proline acetic acid; (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid acetate; H-Gly-Pro-Arg-Pro-OH acetate. CAS No. 157009-81-9. Pack Sizes: 100 mg. Product ID: BAT-009226. Molecular formula: C18H31N7O5.C2H4O2. Mole weight: 485.53. Custom synthesis is available. Send your inquiries for more information. | London |
| GR 64349 | GR 64349 is a potent and selective agonist of tachykinin NK2 receptor (EC50 = 3.7 nM in rat colon). Group: Pharmaceutical. Alternative Names: GR 64349; GR64349; GR-64349; LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2; [LYS3, GLY8-R-GAMMA-LACTAM-LEU9]NEUROKININ A (3-10); L-Lys-L-Asp-L-Ser-L-Phe-L-Val-N-[(3R)-1-[(R)-1-[[[(S)-1-(Aminocarbonyl)-3-(methylthio)propyl]amino]carbonyl]-3-methylbutyl]-2-oxo-3α-pyrrolidi. CAS No. 137593-52-3. Pack Sizes: 1 mg. Product ID: BAT-010280. Molecular formula: C42H68N10O11S. Mole weight: 921.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Gramicidin S | Gramicidin S is an antibiotic produced by the strain of Bacillus brevis. It is effective against some gram-positive and gram-negative bacteria as well as some fungi. Uses: For research use only. Group: Pharmaceutical. Alternative Names: Gramicin S-A; Gramicin S 1; Cyclo(L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl); Gramacidine S; Gramicidina S; Gramicidinum S. CAS No. 113-73-5. Pack Sizes: 10 mg. Product ID: BAT-010152. Molecular formula: C60H92N12O10. Mole weight: 1141.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Grandiflorenic acid | Grandiflorenic acid (GA) is a natural diterpenoid found in the herbs of Siegesbeckia orientalis L. Grandiflorenic acid shows the uterine responses induced by ZACE. Group: Pharmaceutical. Alternative Names: Kauradienoic acid; ent-kaura-9(11),16-dien-18-oic acid; Kaura-9(11),16-dien-18-oic acid, (4α)-; (4R,4aS,6aS,9R,11bR)-4,11b-dimethyl-8-methylene-1,2,3,4,4a,5,6,7,8,9,10,11b-dodecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid; (5β,8α,10α)-Kaura-9(11),16-dien-18-oic acid. CAS No. 22338-67-6. Pack Sizes: 1 mg. Product ID: NP1636. Molecular formula: C20H28O2. Mole weight: 300.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Grandifloric acid | Grandifloric acid is a natural diterpenoid found in the herbs of Siegesbeckia orientalis L. Group: Pharmaceutical. Alternative Names: [15S,(-)]-15α-Hydroxykaur-16-en-18-oic acid; Grandiflorolic acid; 15alpha-Hydroxykaur-16-en-19-oic acid. CAS No. 22338-69-8. Pack Sizes: 1 mg. Product ID: NP1689. Molecular formula: C20H30O3. Mole weight: 318.46. Custom synthesis is available. Send your inquiries for more information. | London |
| Granisetron | Granisetron is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medull. Uses: Granisetron is an antagonist of serptpmom 5-ht3 receptor and could be used to relieve the nausea and vomiting symptom after receving chemotherapy by decreasing the activity of the vagus nerve. Group: Pharmaceutical. Alternative Names: 1-methyl-n-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-indazole-3-carboxamide; 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-, endo-; BRL 43694. CAS No. 109889-09-0. Pack Sizes: 1 g. Product ID: B0084-474340. Molecular formula: C18H24N4O. Mole weight: 312.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Grapiprant (CJ-023423) | Grapiprant, also known as CJ-023,423, RQ-00000007 and AAT-007, is a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. Group: Pharmaceutical. Alternative Names: CJ-023423; CJ 023423; CJ023423; CAS#415903-37-6; RQ-00000007; RQ 00000007; RQ00000007; AAT-007; AAT007; AAT 007; Grapiprant. CAS No. 415903-37-6. Pack Sizes: 10 mg. Product ID: B0084-470919. Molecular formula: C26H29N5O3S. Mole weight: 491.61. Custom synthesis is available. Send your inquiries for more information. | London |
| Grasshopper ketone | Grasshopper Ketone is a natural compound widely used in the research of ailments like Alzheimer's and Parkinson's disease. Group: Pharmaceutical. Alternative Names: 3,5-Dihydroxy-6,7-megastigmadien-9-one; (4R)-4-(3-Oxo-1-buten-1-ylidene)-3α,5,5-trimethylcyclohexane-1α,3β-diol. CAS No. 41703-38-2. Pack Sizes: 1 mg. Product ID: NP6030. Molecular formula: C13H20O3. Mole weight: 224.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Graveoline | Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: a novel apoptosis-independent autophagic signaling pathway. Group: Pharmaceutical. Alternative Names: 2-(benzo[d][1,3]dioxol-5-yl)-1-methylquinolin-4(1H)-one; Foliosine; Graveolin. CAS No. 485-61-0. Pack Sizes: 200 mg. Product ID: B2696-119203. Molecular formula: C17H13NO3. Mole weight: 279.29. Custom synthesis is available. Send your inquiries for more information. | London |
| GRGDS | GRGDS is a synthetic integrin antagonist. Group: Pharmaceutical. Alternative Names: GRGDS; GRGDS 1/2ACOH 2H2O; GRGDS, FIBRONECTIN ATTACHMENT PEPTIDE; GLY-ARG-GLY-ASP-SER; GLY-ARG-GLY-ASP-SER 1/2ACOH 2H2O; H-GLY-ARG-GLY-ASP-SER-OH; glycyl-arginyl-glycyl-aspartyl-serine; GLY-ARG-GLY-ASP-SER ACETATE. CAS No. 96426-21-0. Pack Sizes: 50 mg. Product ID: BAT-010197. Molecular formula: C17H30N8O9. Mole weight: 490.5. Custom synthesis is available. Send your inquiries for more information. | London |
| GRGDSP | GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor which can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization. Group: Pharmaceutical. Alternative Names: H-Gly-Arg-Gly-Asp-D-Ser-Pro-OH; glycyl-L-arginyl-glycyl-L-alpha-aspartyl-D-seryl-L-proline. CAS No. 91037-75-1. Pack Sizes: 10 mg. Product ID: BAT-010499. Molecular formula: C22H37N9O10. Mole weight: 587.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Griffithazanone A | Griffithazanone A is an alkaloid compound found in herbs of Goniothalamus yunnanensis. Group: Pharmaceutical. Alternative Names: (3R,4R)-3,4-Dihydro-3-hydroxy-4-methylbenzo[g]quinoline-2,5,10(1H)-trione. CAS No. 240122-30-9. Pack Sizes: 2 mg. Product ID: NP0149. Molecular formula: C14H11NO4. Mole weight: 257.2. Custom synthesis is available. Send your inquiries for more information. | London |
| Grifolic acid | Grifolic Acid is a selective partial GPR120 agonist. It induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40. Group: Pharmaceutical. Alternative Names: ilicicolinic acid B. CAS No. 80557-12-6. Pack Sizes: 1 mg. Product ID: NP4634. Molecular formula: C23H32O4. Mole weight: 372.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Griseofulvin | It is produced by the strain of Penicillum griseofulvum. It can inhibit the strains of ClassZygomycetes, Ascomycetes and Deuteromycetes (MIC is 1-20 μg/mL), It can also inhibit the crimping of the spore tube of garlic rot grape (MIC is 1 μg/mL). It has obvious inhibitory effect on metaphase mitosis of bone marrow, small intestine and Walker 256 cancer cells. Group: Pharmaceutical. Alternative Names: Curling factor; Fulvicin; Gris PEG; GrisPEG; Gris-PEG; Grisactin; Amudane; 7-Chloro-2',4,6-trimethoxy-6'beta-methylspiro(benzofuran-2(3H), 1'-(2)cyclohexene)-3,4'-dione; (2S-trans)-7-Chloro-2',4,6-trimethoxy-6'-methylspiro(benzofuran-2(3H), 1'-(2)cyclohexene)-3,4'-dione. CAS No. 126-07-8. Pack Sizes: 50 g. Product ID: BBF-01806. Molecular formula: C17H17ClO6. Mole weight: 352.77. Custom synthesis is available. Send your inquiries for more information. | London |
| Groenlandicine | Groenlandicine, a botanical-derived constituent, exhibits profound implications for biomedical applications of studying an array of afflictions, encompassing neoplastic disorders and cardiovascular impairments. Group: Pharmaceutical. Alternative Names: 11,12-Dihydro-8-methoxy-9-hydroxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium; 11,12-Dihydro-9-hydroxy-8-methoxybenzo[a]-1,3-benzodioxolo[4,5-g]quinolizinium; Groenlandicine; Tetrahydricheilanthifolinium; Tetrahydrocheilanthifoline; Tetradehydrocheilanthifoline. CAS No. 38691-95-1. Pack Sizes: 2.5 mg. Product ID: B2703-465676. Molecular formula: C19H16NO4+. Mole weight: 322.33464. Custom synthesis is available. Send your inquiries for more information. | London |
| Grossamide | Cis-Grossamide K is a natural alkaloid found in the herbs of Cannabis sativa L. Cis-Grossamide K exhibits a strong anti-melanogenic activity on the cells without high cell toxicity. Uses: Anti-melanogenic. Group: Pharmaceutical. Alternative Names: 2-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-5-[3-[2-(4-hydroxyphenyl)et hylamino]-3-oxoprop-1-enyl]-7-methoxy-2,3-dihydrobenzofuran-3-carboxamide. CAS No. 80510-06-1. Pack Sizes: 1 mg. Product ID: NP0387. Molecular formula: C36H36N2O8. Mole weight: 624.69. Custom synthesis is available. Send your inquiries for more information. | London |
| Grosvenorine | Grosvenorine is extracted from roots of the fruits of Siraitia grosuenorii. It has free radical scavenging activity. Group: Pharmaceutical. Alternative Names: Grosvenorin. CAS No. 156980-60-8. Pack Sizes: 10 mg. Product ID: B0005-465744. Molecular formula: C33H40O19. Mole weight: 740.7. Custom synthesis is available. Send your inquiries for more information. | London |
| GRP (porcine) | GRP (porcine) is a mammalian bombesin-like peptide neurotransmitter that acts as an agonist for the gastrin-releasing peptide receptor (GRPR). It was shown to activate GABAergic interneurons in the amygdala resulting in an increase in GABA release and fear suppression in mice in vivo. Group: Pharmaceutical. Alternative Names: Gastrin Releasing Peptide porcine. CAS No. 74815-57-9. Pack Sizes: 10 mg. Product ID: B2693-032077. Molecular formula: C126H198N38O31S2. Mole weight: 2805.31. Custom synthesis is available. Send your inquiries for more information. | London |
| GS-441524 | GS-441524 is an analog nucleotide inhibitor against feline infectious peritonitis virus (FIPV). EC50 is 0.78?uM. GS-441524 is also a metabolite and intermediate of Remdesivir. Group: Pharmaceutical. Alternative Names: 2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile; Remdesivir metabolite GS-441524; GS 441524; GS441524; (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile. CAS No. 1191237-69-0. Pack Sizes: 5 g. Product ID: B2693-012542. Molecular formula: C12H13N5O4. Mole weight: 291.26. Custom synthesis is available. Send your inquiries for more information. | London |
| GS967 | GS967, also known as GS-458967, is a highly selective late sodium channel current blocker. The selective inhibition of late INa with GS967 can exert antiarrhythmic effects by suppressing EAD- and DAD-mediated extrasystolic activity in PFs and PV and SVC sleeve preparations. Group: Pharmaceutical. Alternative Names: GS967; GS-967; GS 967; GS458967; GS 458967; GS-458967. CAS No. 1262618-39-2. Pack Sizes: 100 mg. Product ID: B0084-470831. Molecular formula: C14H7F6N3O. Mole weight: 347.22. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK1016790A | GSK1016790A is a novel and potent transient receptor potential vanilloid 4 (TRPV4) agonist. It has been used to demonstrate a role for TRPV4 in regulating urinary bladder activity and endothelial control of vascular tone. It elicited Ca2+ influx in mouse and human TRPV4 expressing HEK cells with EC50 values of 18 and 2.1 nM, respectively. It also evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM, which is 300 fold more potent than 4a-PDD. It was developed by GlaxoSmithKline. Uses: Gsk1016790a regulats urinary bladder activity and endothelial control of vascular tone. Group: Pharmaceutical. Alternative Names: GSK1016790A; GSK-1016790A; GSK 1016790A. N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide. CAS No. 942206-85-1. Pack Sizes: 100 mg. Product ID: B0084-382782. Molecular formula: C28H32Cl2N4O6S2. Mole weight: 655.61. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK1059615 | GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 nM/0.6 nM/2 nM/5 nM and 12 nM, respectively. Group: Pharmaceutical. Alternative Names: GSK-1059615; GSK 1059615; GSK1059615. CAS No. 958852-01-2. Pack Sizes: 50 mg. Product ID: B0084-272127. Molecular formula: C18H11N3O2S. Mole weight: 333.36. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-1070916A | GSK-1070916A is an ATP-competitive inhibitor of the serine/threonine kinases Aurora B and C with potential antineoplastic activity. Aurora B/C kinase inhibitor GSK1070916A binds to and inhibits the activity of Aurora kinases B and C, which may result in inhibition of cellular division and a decrease in the proliferation of tumor cells that overexpress the Aurora kinases B and C. Aurora kinases play essential roles in mitotic checkpoint control during mitosis, and are overexpressed by a wide variety of cancer cell types. Group: Pharmaceutical. Alternative Names: GSK 1070916; GSK-1070916; GSK 1070916; GSK1070916A; GSK 1070916A; NMI-900; NMI 900; NMI900; N'-[4-[4-[2-[3-[(Dimethylamino)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-ethyl-1H-pyrazol-3-yl]phenyl]-N,N-dimethylurea. CAS No. 942918-07-2. Pack Sizes: 25 mg. Product ID: B1370-100932. Molecular formula: C30H33N7O. Mole weight: 507.63. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK126 | GSK126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity. GSK126 decreases global H3K27me3 levels and reactivates silenced PRC2 target genes. GSK126 effectively inhibits the proliferation of EZH2 mutant DLBCL cell lines and markedly inhibits the growth of EZH2 mutant DLBCL xenografts in mice. Together, these data demonstrate that pharmacological inhibition of EZH2 activity may provide a promising treatment for EZH2 mutant lymphoma. Group: Pharmaceutical. Alternative Names: GSK2816126; GSK-2816126; GSK 2816126; GSK-126; GSK 126; (S)-1-(sec-Butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide. CAS No. 1346574-57-9. Pack Sizes: 100 mg. Product ID: B1370-107617. Molecular formula: C31H38N6O2. Mole weight: 526.69. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK1324726A | GSK1324726A is a novel, potent and selective small molecule inhibitor of BET proteins with high affinity to BRD2 (IC50 = 41 nM), BRD3 (IC50 = 31 nM), and BRD4 (IC50 = 22 nM). Group: Pharmaceutical. Alternative Names: I-BET-726; I-BET 726; I-BET726; GSK-1324726A; GSK 1324726A. CAS No. 1300031-52-0. Pack Sizes: 100 mg. Product ID: B1370-463391. Molecular formula: C25H23ClN2O3. Mole weight: 434.91. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK 189254A | GSK-189,254 is a H3 histamine receptor inverse agonist. It has subnanomolar affinity for the H3 receptor with Ki of 0.2nM. It possesses stimulant and nootropic effects and analgesic action suggesting a role for H3 receptors in pain processing in the spinal cord. No development was reported about Phase-II clinical trials for Narcolepsy in Europe. Uses: Narcolepsy. Group: Pharmaceutical. Alternative Names: 6-((3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy)-N-methyl-3-Pyridinecarboxamide. CAS No. 720690-73-3. Pack Sizes: 300 mg. Product ID: B0084-459482. Molecular formula: C21H25N3O2. Mole weight: 351.44. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-2018682 | GSK-2018682 is a potent and selective agonist of sphingosine-1-phosphate receptor (S1PR) subtype 1 that has the potential to treat multiple sclerosis (MS). Group: Pharmaceutical. Alternative Names: GSK2018682; GSK 2018682; GSK-2018682. UNII-NJL503AIJA; NJL503AIJA; 4-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl)-1H-indol-1-yl)butanoic acid. CAS No. 1034688-30-6. Pack Sizes: 10 mg. Product ID: B0084-008117. Molecular formula: C22H21ClN4O4. Mole weight: 440.884. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK2193874 | GSK2193874 is a potent, orally active and specific antagonist of TRPV4 ion channels (IC50 values 2 and 40 nM for rat and human receptors, respectively). GSK2193874 is selective over a panel of ~200 human receptors, channels and enzymes. Group: Pharmaceutical. Alternative Names: GSK2193874; GSK 2193874; GSK-2193874; GSK2193874A; GSK 2193874A; GSK-2193874A; 7-bromo-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl) methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide. CAS No. 1336960-13-4. Pack Sizes: 20 mg. Product ID: B0084-007718. Molecular formula: C37H38BrF3N4O. Mole weight: 691.62. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-2256098 | GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. Group: Pharmaceutical. Alternative Names: GSK2256098; GSK 2256098; GSK-2256098; GTPL7939; GTPL-7939; GTP L7939. CAS No. 1224887-10-8. Pack Sizes: 100 mg. Product ID: B0084-470953. Molecular formula: C20H23ClN6O2. Mole weight: 414.89. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK2256294A | GSK2256294A, an effective inhibitor of human soluble epoxide hydrolase(sEH), was developed by GSK and still under Phase I trial in Chronic obstructive pulmonary disease. IC50: 27pM. Uses: Gsk2256294a is an effective inhibitor of human soluble epoxide hydrolase(seh). Group: Pharmaceutical. Alternative Names: GSK2256294; GSK-2256294; GSK 2256294; GSK-2256294A; GSK 2256294A. CAS No. 1142090-23-0. Pack Sizes: 100 mg. Product ID: B1370-190587. Molecular formula: C21H24F3N7O. Mole weight: 447.46. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK 2606414 | GSK 2606414 is a potent and selective PERK inhibitor that suppresses PERK activation in cells and inhibits the growth of a human tumor xenograft in mice. Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is activated in response to a variety of endoplasmic reticulum stresses implicated in numerous disease states. Evidence that PERK is implicated in tumorigenesis and cancer cell survival stimulated our search for small-molecule inhibitors. Group: Pharmaceutical. Alternative Names: GSK2606414; GSK-2606414; GSK 2606414; GSK PERK Inhibitor. 1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone. CAS No. 1337531-36-8. Pack Sizes: 100 mg. Product ID: B0084-462365. Molecular formula: C24H20F3N5O. Mole weight: 451.453. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-2881078 | GSK-2881078, an indole derivative, has been found to be an androgen receptor modulator that could probably be effective against Cachexia. It is still under Phase I trail. Uses: Anabolic agents. Group: Pharmaceutical. Alternative Names: GSK 2881078; GSK2881078; CS-5736; (R)-1-(1-(methylsulfonyl)propan-2-yl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile. CAS No. 1539314-06-1. Pack Sizes: 25 mg. Product ID: B2693-475855. Molecular formula: C14H13F3N2O2S. Mole weight: 330.33. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK2982772 | GSK2982772, with potential effect to treat inflammatory diseases, potently binds to RIP1 with exquisite kinase specificity. In phase 2a clinical studies for psoriasis, rheumatoid arthritis, and ulcerative colitis. Group: Pharmaceutical. Alternative Names: GSK2982772; GSK 2982772; GSK-2982772; 5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide. CAS No. 1622848-92-3. Pack Sizes: 100 mg. Product ID: B0084-007719. Molecular formula: C20H19N5O3. Mole weight: 377.4. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK3326595 | GSK3326595, also called as EPZ015938, is an orally available and specific inhibitor of protein arginine methyltransferase 5 (PRMT5) that potently inhibits tumor growth in vitro and in vivo in animal models and has entered clinical trials for the treatment of solid tumors and non-Hodgkin's lymphoma. Group: Pharmaceutical. Alternative Names: GSK-3326595; GSK 3326595; GSK3326595; EPZ015938; EPZ 015938; EPZ-015938; 6-[(1-acetylpiperidin-4-yl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyrimidine-4-carboxamide. CAS No. 1616392-22-3. Pack Sizes: 100 mg. Product ID: B2693-007330. Molecular formula: C24H32N6O3. Mole weight: 452.55. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-3787 | GSK-3787 is a potent and selective ligand for PPARdelta with good pharmacokinetic properties. Group: Pharmaceutical. Alternative Names: GSK-3787; GSK3787; GSK 3787. CAS No. 188591-46-0. Pack Sizes: 50 mg. Product ID: B0084-272130. Molecular formula: C15H12ClF3N2O3S. Mole weight: 392.78059. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-461364 | GSK-461364 is a Polo-like kinase 1 inhibitor, is also a small molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor GSK461364 selectively inhibits Plk1, inducing selective G2/M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. Plk1, named after the polo gene of Drosophila melanogaster, is a serine/threonine protein kinase involved in regulating mitotic spindle function in a non-ATP competitive manner. Group: Pharmaceutical. Alternative Names: GSK461364; GSK 461364; GSK-461364; GSK461364A; GSK 461364A; GSK-461364A. 5-[6-[(4-Methyl-1-piperazinyl)methyl]-1h-benzimidazol-1-yl]-3-[(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy]-2-thiophenecarboxamide. CAS No. 929095-18-1. Pack Sizes: 10 mg. Product ID: B0084-307746. Molecular formula: C27H28F3N5O2S. Mole weight: 543.609. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK525762 | GSK525762A, also known as I-BET-762 and GSK525762, is a small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins with potential antineoplastic activity. Upon administration, the BET inhibitor GSK525762 binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes may lead to an inhibition of tumor cell growth. Characterized by a tandem repeat of bromodomain at the N-terminus, BET proteins, comprising of BRD2, BRD3, BRD4 and BRDT, are transcriptional regulators that play an important role during development and cellular growth. Group: Pharmaceutical. Alternative Names: GSK525762; GSK525762; GSK525762; GSK525762A; GSK-525762A; GSK 525762A; I-BET-762; I-BET762; I-BET 762; molibresib. CAS No. 1260907-17-2. Pack Sizes: 25 mg. Product ID: B2693-457801. Molecular formula: C22H22ClN5O2. Mole weight: 423.9. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK547 | GSK547 is a highly selective and potent RIP1 (RIPK1) inhibitor which displays 400-fold improvement in mouse pharmacokinetic oral exposure compared with GSK963. Group: Pharmaceutical. Alternative Names: RIP1i. CAS No. 2226735-55-1. Pack Sizes: 10 mg. Product ID: B2693-334088. Molecular formula: C20H18F2N6O. Mole weight: 396.39. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK583 | GSK583 is a selective receptor-interacting serine/threonine-protein kinase 2 (RIP2 Kinase) inhibitor and the RIP2K binding IC50 is 5 nM. GSK583 can inhibit both TNF-α and IL-6 production with an IC50 value of 200 nM in an ex vivo human translational model. Group: Pharmaceutical. Alternative Names: GSK583; GSK 583; GSK-583. 6 - (tert-Butylsulfonyl) - N - (5-fluoro - 1H - indazol-3-yl)quinolin-4-amine. CAS No. 1346547-00-9. Pack Sizes: 25 mg. Product ID: B0084-475334. Molecular formula: C20H19FN4O2S. Mole weight: 398.46. Custom synthesis is available. Send your inquiries for more information. | London |
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