BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| IAXO-102 | IAXO-102 is a TLR4 antagonist that modulates non-hematopoietic TLR4 proinflammatory signalling and inhibits experimental abdominal aortic aneurysm (AAA) development. Group: Pharmaceutical. Alternative Names: IAXO-102; 1115270-63-7; CID 25222900; (2R,3R,4S,5R,6S)-2-(aminomethyl)-6-methoxy-4,5-di(tetradecoxy)oxan-3-ol; CHEMBL493017; SCHEMBL20239315; EX-A3691; AKOS037648519; BS-14387; HY-125171; CS-0089755; D70080; Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-|A-D-glucopyranoside. CAS No. 1115270-63-7. Pack Sizes: 5 mg. Product ID: B2693-380035. Molecular formula: C35H71NO5. Mole weight: 585.94. Custom synthesis is available. Send your inquiries for more information. |  London |
| Ibafloxacin | Ibafloxacin is a fluoroquinolone antibiotic drug used in veterinary medicine. Group: Pharmaceutical. Alternative Names: Ibafloxacine; R-835; S-25930; 6,7-Dihydro-9-fluoro-5,8-dimethyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid; 9-Fluoro-6,7-dihydro-5,8-dimethyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid. CAS No. 91618-36-9. Pack Sizes: 1mg;1g;10g. Product ID: 91618-36-9. Molecular formula: C15H14FNO3. Mole weight: 275.279. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibandronate Sodium Monohydrate | Ibandronate (< 100 μM) inhibits growth of both prostate cancer cell lines (LNCaP and PC-3) in a dose dependent manner. Group: Pharmaceutical. Alternative Names: BM-21.0955. CAS No. 138926-19-9. Pack Sizes: 10 g. Product ID: B0046-464101. Molecular formula: C9H23NO7P2.Na.H2O. Mole weight: 360.23. Custom synthesis is available. Send your inquiries for more information. | London |
| I-BET151 | I-BET151 is a BET bromodomain inhibitor, which blocks recruitment of BET to chromatin. It was shown to induce early cell cycle arrest and apoptosis in human and mouse MLL-fusion leukemia cell lines. Group: Pharmaceutical. Alternative Names: GSK1210151A; 7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one. CAS No. 1300031-49-5. Pack Sizes: 25 mg. Product ID: B0084-457872. Molecular formula: C23H21N5O3. Mole weight: 415.453. Custom synthesis is available. Send your inquiries for more information. | London |
| I-BET762 carboxylic acid | I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1. Group: Pharmaceutical. Alternative Names: Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2. CAS No. 1300019-38-8. Pack Sizes: 5 mg. Product ID: B2693-291851. Molecular formula: C20H17ClN4O3. Mole weight: 396.83. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibiglustat | Ibiglustat is a selective Glucosylceramide synthase inhibitor. It can block the formation of glucosylceramide (GL-1) which is a key intermediate in the synthesis of GL-3. In Oct 2016, Genzyme completed a phase II trial in Fabry's disease (Treatment-naïve) in USA, Czech Republic, France, Poland, Russia and the UK. Phase-II clinical trials in Gaucher's disease in USA is on-going. Uses: Fabry's disease; gaucher's disease. Group: Pharmaceutical. Alternative Names: Venglustat; GZ-402671; GZ402671; GZ 402671; SSAR402671; SAR-402671; SAR 402671; Genz-682452-AA; GZ-452; Genz-682452; GZ 452; Genz 682452; GZ452; (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate. CAS No. 1401090-53-6. Pack Sizes: 100 mg. Product ID: B1370-198606. Molecular formula: C20H24FN3O2S. Mole weight: 389.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibotenic acid | Ibotenic acid is a neuroexcitatory amino acid originally isolated from amanita species. It is used as a non-selective NMDA and metabotropic glutamate receptor agonist. It is a neurotoxin and is often used to induce brain lesions in animals. It has been used to perform surgery in adult male zebra finches to study reversing reinforcement-induced vocal changes. Group: Pharmaceutical. Alternative Names: (+/-)-Ibotenic acid; DL-Ibotenic acid. CAS No. 2552-55-8. Pack Sizes: 25 mg. Product ID: B1370-060612. Molecular formula: C5H6N2O4. Mole weight: 158.11. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibrexafungerp | Ibrexafungerp, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Group: Pharmaceutical. Alternative Names: Brexafemme; SCY-078; MK3118; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-. CAS No. 1207753-03-4. Pack Sizes: 10 mg. Product ID: BBF-05813. Molecular formula: C44H67N5O4. Mole weight: 730.03. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibrexafungerp Citrate | Ibrexafungerp Citrate, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Group: Pharmaceutical. Alternative Names: Brexafemme Citrate; SCY-078 Citrate; MK-3118 Citrate; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt). CAS No. 1965291-08-0. Pack Sizes: 10 mg. Product ID: BBF-05812. Molecular formula: C50H75N5O11. Mole weight: 922.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibrutinib Dimer | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Group: Pharmaceutical. Alternative Names: Ibrutinib impurity MDAEJ; 2-Propen-1-one, 1-[(3R)-3-[4-[[3-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-oxopropyl]amino]-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-; 1-((R)-3-(4-((3-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-oxopropyl)amino)-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. CAS No. 2031255-23-7. Pack Sizes: 100 mg. Product ID: B1370-377850. Molecular formula: C50H48N12O4. Mole weight: 880.99. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibrutinib Impurity 1 | An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Group: Pharmaceutical. Alternative Names: 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)-; (R)-tert-Butyl 3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate. CAS No. 1022150-11-3. Pack Sizes: 2 g. Product ID: B2694-472295. Molecular formula: C27H30N6O3. Mole weight: 486.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibudilast | Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Group: Pharmaceutical. Alternative Names: MN-166, MN166, MN 166, AV-411, AV 411, AV411, KC404; KC-404; KC 404; Ibudilast. CAS No. 50847-11-5. Pack Sizes: 5 g. Product ID: B0084-329045. Molecular formula: C14H18N2O. Mole weight: 230.31. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibuprofen EP Impurity A | Ibuprofen EP Impurity A is an Ibuprofen impurity used in the study of potent noncompetitive interleukin-8 inhibitors. Group: Pharmaceutical. Alternative Names: m-Isobutyl Ibuprofen; (2RS)-2-[3-(2-Methylpropyl)phenyl] propanoic acid; 2-(3-isobutylphenyl)propanoic acid; α-Methyl-3-(2-methylpropyl)benzeneacetic Acid,α-(3-Isobutylphenyl)propionic Acid. CAS No. 66622-47-7. Pack Sizes: 50 mg. Product ID: B2694-212873. Molecular formula: C13H18O2. Mole weight: 206.29. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibuprofen EP Impurity J | Ibuprofen EP Impurity J is an Ibuprofen impurity used in the study of potent noncompetitive interleukin-8 inhibitors. Group: Pharmaceutical. Alternative Names: Ibuprofen USP Related Compound J; Ibuprofen BP ImpurityJ; 1-Oxo Ibuprofen; α-Methyl-4-(2-methyl-1-oxopropyl)benzeneacetic Acid; (2RS)-2-(4-Isobutyrylphenyl)propanoic acid. CAS No. 65813-55-0. Pack Sizes: 25 mg. Product ID: B2694-147018. Molecular formula: C13H16O3. Mole weight: 220.27. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibuprofen EP Impurity K | Ibuprofen EP Impurity K is a degradation product of Ibuprofen arising from oxidative and thermal treatment. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain. Group: Pharmaceutical. Alternative Names: Ibuprofen BP Impurity K; 2-(4-Formyl-phenyl)-Propionic Acid; rac 2-(4-Formylphenyl)propionic Acid; 4-Formyl-α-methylbenzeneacetic Acid; 2-(p-Formylphenyl)propionic Acid; (2RS)-2-(4-Formylphenyl)propanoic Acid. CAS No. 43153-07-7. Pack Sizes: 100 mg. Product ID: B2694-212829. Molecular formula: C10H10O3. Mole weight: 178.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibuprofen EP Impurity L | Ibuprofen EP Impurity L is a degradation product of Ibuprofen, a nonsteroidal anti-inflammatory drug. Group: Pharmaceutical. Alternative Names: Ibuprofen BP Impurity L; 1-Hydroxyibuprofen; 4-(1-Hydroxy-2-methylpropyl)-α-methylbenzeneacetic Acid. CAS No. 53949-53-4. Pack Sizes: 25 mg. Product ID: B2694-123429. Molecular formula: C13H18O3. Mole weight: 222.29. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibuprofen lysine | Ibuprofen lysine is a non-selective COX inhibitor that can be used as an anti-inflammatory drug. Group: Pharmaceutical. Alternative Names: Arflamin; NeoProfen; Saren. CAS No. 57469-77-9. Pack Sizes: 2 g. Product ID: B2693-072008. Molecular formula: C19H32N2O4. Mole weight: 352.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Ibuprofen piconol | Ibuprofen piconol is an anti-inflammatory agent that can be synthesized from Ibuprofen. It acts as a cyclooxygenase inhibitor. Group: Pharmaceutical. Alternative Names: Pimeprofen; Staderm; Vesicum; pyridin-2-ylmethyl 2-[4-(2-methylpropyl)phenyl]propanoate. CAS No. 64622-45-3. Pack Sizes: 5 g. Product ID: B0046-448719. Molecular formula: C19H23NO2. Mole weight: 297.4. Custom synthesis is available. Send your inquiries for more information. | London |
| ICA-069673 | ICA-069673 is an orally active, potent and selective KCNQ2/Q3 potassium channel activator (IC50= 0.69 μM) with 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5 (EC50s = 14.3 μM). Group: Pharmaceutical. Alternative Names: ICA 069673; ICA069673. CAS No. 582323-16-8. Pack Sizes: 100 mg. Product ID: B2693-007304. Molecular formula: C11H6ClF2N3O. Mole weight: 269.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Icariin | Icariin is a flavonol glycoside and a PDE5 inhibitor (IC50 = 5.9 μM) with 67-fold selectivity for PDE5 over PDE4. It exhibits antioxidant and anticancer activity. At a concentration of 1 x 107 mol/L, Icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes. At 20 μg/ml, Icariin increases the proliferation and differentiation of cultured human osteoblasts. Icariin affects the aging mechanism from different aspects, can delay the aging process and prevent the occurrence of senile diseases. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: 3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-7-b-D-glucopyranosyloxy-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one. CAS No. 489-32-7. Pack Sizes: 5 g. Product ID: NP1908. Molecular formula: C33H40O15. Mole weight: 676.66. Custom synthesis is available. Send your inquiries for more information. | London |
| Icariside E5 | Icariside E5 is a lignan glycoside isolated from the herbs of Epimedium brevicornu. It has antioxidant property that strengthens the importance of peppers in the Mediterranean diet. Uses: Antioxidant property. Group: Pharmaceutical. Alternative Names: 3-[4-β-D-Glucopyranosyloxy-5-methoxy-3-[2-(4-hydroxy-3-methoxyphenyl)-1-(hydroxymethyl)ethyl]phenyl]-2-propen-1-ol; 2-[(2R)-1-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)-2-propanyl]-4-[(1 E)-3-hydroxy-1-propen-1-yl]-6-methoxyphenyl β-D-glucopyranoside. CAS No. 126176-79-2. Pack Sizes: 1 mg. Product ID: NP4028. Molecular formula: C26H34O11. Mole weight: 522.54. Custom synthesis is available. Send your inquiries for more information. | London |
| Icariside I | Icariside I is extracted from the herbs of Epimedium brevicornum Maxim. Group: Pharmaceutical. Alternative Names: Icariin I. CAS No. 56725-99-6. Pack Sizes: 25 mg. Product ID: B2703-464608. Molecular formula: C27H30O11. Mole weight: 530.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Icariside II | A regulator of CXCR4 expression. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one; Baohuoside 1; Baohuoside I; Baohuside I; Icariin II; Icariside II. CAS No. 113558-15-9. Pack Sizes: 50 mg. Product ID: NP1910. Molecular formula: C27H30O10. Mole weight: 514.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Icaritin | Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or ti | London |
| Icatibant Acetate | Icatibant acetate is a selective antagonist of bradykinin B2 receptors. Icatibant is a medication approved for the treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. Alternative Names: HOE 140 Acetate; HOE140 Acetate; HOE-140 Acetate; L-Arginine, D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-, acetate (1:x); H-D-Arg-Arg-Pro-Hyp-Gly-2Thi-Ser-D-Tic-Oic-Arg-OH.CH3CO2H; L-Arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3aβ,7aβ)-octahydro-1H-indole-2-carbonyl-, acetate (salt); Firazyr. CAS No. 138614-30-9. Pack Sizes: 10 mg. Product ID: BAT-010084. Molecular formula: C59H89N19O13S.xC2H4O2. Mole weight: 1304.52 (free base). Custom synthesis is available. Send your inquiries for more information. | London |
| ICEC-0942 | ICEC-0942 is a small-molecule cyclin-dependent kinase 7 (CDK7) inhibitor developed for cancer therapy. Preclinical study in Acute Myeloid Leukaemia (AML) models shows that ICEC-0942 effectively inhibits the proliferation of several AML cell lines and patient derived AML cells in vitro (IC50 = 0.15-2.6 μM). Uses: Anticancer drug. Group: Pharmaceutical. Alternative Names: CT7001; CT 7001; CT-7001; ICEC0942; ICEC0 942; ICEC0-942. CAS No. 1805833-75-3. Pack Sizes: 10 mg. Product ID: B0084-008621. Molecular formula: C22H30N6O. Mole weight: 394.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Icilin | Icilin is a synthetic CMR1/TRPM8 super agonist in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM) more potently than menthol or low temperatures. Uses: Both heat sensitive (vr1) and cold-sensitive (cmr1 (rat); trpm8 (human)) receptors. Group: Pharmaceutical. Alternative Names: AG 3-5; AG3-5; AG-3-5; AG 3-5 cpd; 3,4-Dihydro-3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-(1H)-pyrimidin-2-one;3,6-dihydro-1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-2(1H)-pyrimidinone. CAS No. 36945-98-9. Pack Sizes: 50 mg. Product ID: B0084-113190. Molecular formula: C16H13N3O4. Mole weight: 311.29. Custom synthesis is available. Send your inquiries for more information. | London |
| Iclaprim | Iclaprim is a diaminopyrimidine and acts as a dihydrofolate reductase (DHFR) inhibitor active against gram-positive organisms being developed for the treatment of complicated skin and soft tissue infections caused by antibiotic-resistant bacteria. Group: Pharmaceutical. Alternative Names: AR-100; 5-[(2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-yl)methyl]pyrimidine-2,4-diamine; RO-48-2622. CAS No. 192314-93-5. Pack Sizes: 2 mg. Product ID: B0084-244921. Molecular formula: C19H22N4O3. Mole weight: 354.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Icosanal | Icosanal. Group: Pharmaceutical. Alternative Names: Icosanal;Eicosanal;2400-66-0;FWBUWJHWAKTPHI-UHFFFAOYSA-N;EINECS219-275-5;AI3-24217. CAS No. 2400-66-0. Pack Sizes: 100 mg. Product ID: B0001-273983. Molecular formula: C20H40O. Mole weight: 296.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Icosanamide | Icosanamide, a derivative of fatty acid, displays promise as a therapeutic agent for diverse inflammatory ailments. With its impressive anti-inflammatory attributes, the compound has garnered attention for handling autoimmune diseases and treating conditions such as rheumatoid arthritis. Its efficacy is well-documented in several clinical studies. Group: Pharmaceutical. Alternative Names: Eicosanamide; Arachamide. CAS No. 51360-63-5. Pack Sizes: 100 mg. Product ID: B0001-274275. Molecular formula: C20H41NO. Mole weight: 311.554. Custom synthesis is available. Send your inquiries for more information. | London |
| Icotinib | Icotinib Hydrochloride (BPI-2009H), or Icotinib, is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Group: Pharmaceutical. Alternative Names: BPI-2009H. CAS No. 610798-31-7. Pack Sizes: 300 mg. Product ID: B0084-459334. Molecular formula: C22H21N3O4. Mole weight: 391.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Icotinib hydrochloride | Icotinib Hydrochloride is a quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), which is upregulated in a variety of cancer cell types. Icotinib supresses the cancer cell proliferation via EGFR tyrosine kinase inhibition. Group: Pharmaceutical. Alternative Names: Icotinib HCl; BPI-2009; BPI 2009; BPI2009. CAS No. 1204313-51-8. Pack Sizes: 300 mg. Product ID: BBF-04036. Molecular formula: C22H22ClN3O4. Mole weight: 427.88. Custom synthesis is available. Send your inquiries for more information. | London |
| iCRT 14 | iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling. It is thought to directly influence the interaction between β-catenin and TCF4. It also induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. Group: Pharmaceutical. Alternative Names: iCRT14; iCRT-14; iCRT 14; Wnt inhibitor; CHEMBL3589010; STK155594; 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione. CAS No. 677331-12-3. Pack Sizes: 25 mg. Product ID: B0084-272145. Molecular formula: C21H17N3O2S. Mole weight: 375.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Idarubicinone | Idarubicinone is a derivative of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Group: Pharmaceutical. Alternative Names: 4-demethoxy daunomycinone; (7S,9S)-9-acetyl-6,7,9,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione; 4-Demethoxydaunomycinone; Idarubicin aglycone; (+)-4-Demethoxydaunomycinone; 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-, (7S-cis)-; (+)-Idarubicinone; (8S,10S)-7,8,9,10-Tetrahydro-6,8,10,11-tetrahydroxy-8-acetyl-5,12-naphthacenedione. CAS No. 60660-75-5. Pack Sizes: 5 mg. Product ID: B0709-003996. Molecular formula: C20H16O7. Mole weight: 368.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Idasanutlin | Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM2 antagonist with potential anticancer activity. RG7388 binds to MDM2 blocking the interaction between the MDM2 protein and the transcriptional activation domain of the tumor suppressor protein p53. By preventing the MDM2-p53 interaction, p53 is not enzymatically degraded and the transcriptional activity of p53 is restored. This may lead to p53-mediated induction of tumor cell apoptosis. MDM2, a zinc finger nuclear phosphoprotein and negative regulator of the p53 pathway, is often overexpressed in cancer cells and has been implicated in cancer cell proliferation and survival. Uses: For research used only. Group: Pharmaceutical. Alternative Names: RG7388; RG 7388; RG-7388; RO5503781; RO-5503781; RO 5503781. CAS No. 1229705-06-9. Pack Sizes: 200 mg. Product ID: B0084-462568. Molecular formula: C31H29Cl2F2N3O4. Mole weight: 616.487. Custom synthesis is available. Send your inquiries for more information. | London |
| Idebenone | Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. Idebenone is a smart promoting drug, which is mainly used in the treatment of many degenerative diseases of the central nervous system related to oxidative compressions, such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and cerebral failure, and is also used in the treatment of Friedreich's ataxia. It can also be used in cosmetic formulations to clear free radicals, inhibit lipid peroxidation, inhibit inflammation, inhibit DNA damage, photoprotection, reduce pigmentation, and other cosmetic effects. Group: Pharmaceutical. Alternative Names: CV 2619; CV-2619; CV2619; Catena; Raxone; Sovrima; 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione; 2,3-Dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone; 2,3-Dimethoxy-6-(10-hydroxydecyl)-5-methyl-1,4-benzoquinone; 2-(10-Hydroxy-decyl)-5,6-dimethoxy-3-methyl-[1,4]benzoquinone; Avan; Daruma; Hydroxydecyl ubiquinone; Mnesis. CAS No. 58186-27-9. Pack Sizes: 10 g. Product ID: NP3168. Molecular formula: C19H30O5. Mole weight: 338.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Idelalisib | Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Group: Pharmaceutical. Alternative Names: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. CAS No. 870281-82-6. Pack Sizes: 250 mg. Product ID: B0084-307712. Molecular formula: C22H18FN7O. Mole weight: 415.432. Custom synthesis is available. Send your inquiries for more information. | London |
| Ifenprodil Tartrate | Ifenprodil is an atypical noncompetitive antagonist at the NMDA receptor, it interacts with high affinity at a homogeneous population of NMDA receptors in neonatal rat forebrain with IC50 of 0.3 μM. Uses: Adrenergic alpha-antagonists. Group: Pharmaceutical. Alternative Names: Ifenprodil (tartrate). CAS No. 23210-58-4. Pack Sizes: 1 g. Product ID: B2693-367328. Molecular formula: 2(C21H27NO2).C4H6O6. Mole weight: 800.98. Custom synthesis is available. Send your inquiries for more information. | London |
| IFN alpha-IFNAR-IN-1 hydrochloride | IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptide, low-molecular-weight inhibitor. It inhibits modified Vaccinia virus ankara (MVA)-induced IFN-α responses in murine bone-marrow-derived, Flt3-L-differentiated pDC cultures (BM-pDCs) (IC50=2-8 μM). Group: Pharmaceutical. Alternative Names: IFN alpha-IFNAR-IN-1 (hydrochloride); IFN-α-IFNAR-IN-1 (hydrochloride). CAS No. 2070014-98-9. Pack Sizes: 50 mg. Product ID: B1370-447064. Molecular formula: C18H18ClNS. Mole weight: 315.86. Custom synthesis is available. Send your inquiries for more information. | London |
| Ifosfamide | Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer. Uses: Antineoplastic agents, alkylating. Group: Pharmaceutical. Alternative Names: 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide; 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide; (2-Chloro-ethyl)-[3-(2-chloro-ethyl)-2-oxo-2λ*5*-[1,3,2]oxazaphosphinan-2-yl]-amine; (±)-Ifosfamide; 3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; A 4942; Asta Z 4942; Cyfos; Holoxan; Holoxan 1000; Ifex; Ifomide; Ifosfamid; Ifosfomide; Ifosphamide; Iphosphamide; Isoendoxan; Isofosfamide; Isophosphamide; Mitoxana; MJF 9325; Naxamide; NSC 109724; Z 4942. CAS No. 3778-73-2. Pack Sizes: 5 g. Product ID: B2693-114093. Molecular formula: C7H15Cl2N2O2P. Mole weight: 261.09. Custom synthesis is available. Send your inquiries for more information. | London |
| IGF-1 LR3 | IGF-1 LR3 is a lengthened analogue of human insulin-like growth factor 1 (IGF-1). Group: Pharmaceutical. Alternative Names: Long R3-IGF-1; IGF-1 Long R3; Long arginine 3-IGF-1. CAS No. 946870-92-4. Pack Sizes: 5 mg. Product ID: BAT-006251. Molecular formula: C400H625N111O115S9. Mole weight: 9117.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Iguratimod | Iguratimod is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor. Uses: Anti-inflammation agent. Group: Pharmaceutical. Alternative Names: T 614; T-614; T614; N-(7-(Methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide; Careram; Kolbet; UNII-4IHY34Y2NV. CAS No. 123663-49-0. Pack Sizes: 250 mg. Product ID: B0084-056331. Molecular formula: C17H14N2O6S. Mole weight: 374.367. Custom synthesis is available. Send your inquiries for more information. | London |
| IKK 16 hydrochloride | IKK 16 hydrochloride is a potent and selective IκB kinase (IKK) inhibitor with IC50s of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα, respectively. It inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells. Group: Pharmaceutical. Alternative Names: N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamide hydrochloride; [4-[(4-Benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone hydrochloride; Methanone, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-, hydrochloride (1:1). CAS No. 1186195-62-9. Pack Sizes: 50 mg. Product ID: B1370-470817. Molecular formula: C28H30ClN5OS. Mole weight: 520.09. Custom synthesis is available. Send your inquiries for more information. | London |
| Ilaprazole | Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. It significantly prevented the development of reflux oesophagitis. Group: Pharmaceutical. Alternative Names: 2-[(4-methoxy-3-methyl-pyridin-2-yl)methylsulfinyl]-5-pyrrol-1-yl-3H-benzoimidazole; IY 81149; 1H-BenziMidazole,2-[[(4-Methoxy-3-Methyl-2-pyridinyl)Methyl]sulfinyl]-6-(1H-pyrrol-1-yl)-. CAS No. 172152-36-2. Pack Sizes: 1mg;1g;10g. Product ID: NP3627. Molecular formula: C19H18N4O2S. Mole weight: 366.44. Custom synthesis is available. Send your inquiries for more information. | London |
| ILK-IN-1 | ILK-IN-1, a ILK inhibitor, has been found to restrain the tumor cell growth through regulating signaling pathways related to oncogenesis and tumor progression. IC50: 0.6 μM. Uses: Ilk-in-1 is a ilk inhibitor that has been found to restrain the tumor cell growth through regulating signaling pathways related to oncogenesis and tumor progression. Group: Pharmaceutical. Alternative Names: ILK-IN-1; CHEMBL1830587; GTPL8116; SCHEMBL8536228; BDBM50353484; CS-4936; ILK inhibitor 22(1,5); T315(1,5); OSU-T315 (1,5-regioisomer); OSUT315; OSU T315; OSU-T315. CAS No. 1333146-24-9. Pack Sizes: 10 mg. Product ID: B2693-474480. Molecular formula: C30H30F3N5O. Mole weight: 533.59. Custom synthesis is available. Send your inquiries for more information. | London |
| Illudin S | Illudin S is a natural sesquiterpene agent with strong anti-tumour activity. Illudin S inhibits DNA synthesis via an unknown mechanism. Group: Pharmaceutical. Alternative Names: (-)-Illudin S; Lampterol; Lunamycin; (-)-1alpha,7beta,12-trihydroxy-2,9-illudadien-8-one; 2',3'-Dihydro-2',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethylspiro(cyclopropane-1,5'-(5H)inden)-7'(6'H)-one. CAS No. 1149-99-1. Pack Sizes: 2.5 mg. Product ID: BBF-01877. Molecular formula: C15H20O4. Mole weight: 264.32. Custom synthesis is available. Send your inquiries for more information. | London |
| Ilomastat | Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor, displaying potential anticancer activity. Ilomastat is a member of the hydroxamic acid class of reversible metallopeptidase inhibitors. The anionic state of the hydroxamic acid group forms a bidentate complex with the active site zinc. Ilomastat inhibits enzymes including thermolysin, peptide deformylase, and anthrax lethal factor endopeptidase (LF) produced by the bacterium Bacillus anthracis. Group: Pharmaceutical. Alternative Names: GM6001; GM-6001; GM 6001; Ilomastat; galardin; (2R)-N'-hydroxy-N-[(2S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl]-2-(2-methylpropyl)butanedia. CAS No. 142880-36-2. Pack Sizes: 25 mg. Product ID: B0084-302725. Molecular formula: C20H28N4O4. Mole weight: 388.468. Custom synthesis is available. Send your inquiries for more information. | London |
| Iloperidone | Iloperidone displays high affinity (Ki < 10 nM) for norepinephrine alpha(1)-adrenoceptors, dopamine D(3) and serotonin 5-HT(2A) receptors. Uses: An atypical, negative symptom antipsychotic agent. Group: Pharmaceutical. Alternative Names: HP873; HP 873; HP-873. CAS No. 133454-47-4. Pack Sizes: 1mg;1g;10g. Product ID: NP3480. Molecular formula: C24H27FN2O4. Mole weight: 426.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib | Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with an IC50 for these effects of approximately 0.1 μM, which is similar to the concentration required for inhibition of PDGFR. Imatinib is an oral chemotherapy agent used to treat cancers. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+), certain types of gastrointestinal stromal tumors (GIST), hypereosinophilic syndrome (HES), chronic eosinophilic leukemia (CEL), systemic mastocytosis, and myelodysplastic syndrome. Group: Pharmaceutical. Alternative Names: CGP057148B; STI571; Gleevec; Glivec; N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide; 4-[(4-Methyl-1-piperazinyl)methyl]-N-(4-methyl-3-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}phenyl)benzamide. CAS No. 152459-95-5. Pack Sizes: 10 g. Product ID: BBF-05855. Molecular formula: C29H31N7O. Mole weight: 493.6. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib-[d4] | Imatinib-[d4] is an isotopically labelled analogue of Imatinib. Imatinib is an inhibitor of multiple tyrosine kinases. It is a COVID-19-related research product. Group: Pharmaceutical. Alternative Names: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide-2,3,5,6-d4; Imatinib D4. CAS No. 1134803-16-9. Pack Sizes: 5 mg. Product ID: BLP-005865. Molecular formula: C29H27D4N7O. Mole weight: 497.64. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib EP Impurity D | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Group: Pharmaceutical. Alternative Names: Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride; 1-Methyl-1,4-bis[4-[(4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl)carbamoyl]benzyl]piperazin-1-ium chloride. CAS No. 1821122-73-9. Pack Sizes: 100 mg. Product ID: B2694-473167. Molecular formula: C53H51ClN12O2. Mole weight: 923.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib EP Impurity J | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Group: Pharmaceutical. Alternative Names: Imatinib (Piperidine)-N-oxide; 4-[(4-Methyl-4-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide; CGP 71422; CGP71422; CGP-71422. CAS No. 571186-91-9. Pack Sizes: 10 mg. Product ID: B2694-473158. Molecular formula: C29H31N7O2. Mole weight: 509.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib Guanidine Impurity | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Group: Pharmaceutical. Alternative Names: N-(3-Guanidino-4-methylphenyl)-4-(methylpiperazine-1-yl-methyl)benzamide; N-[3-[(Aminoiminomethyl)amino]-4-methylphenyl]-4-[(4-methyl-1-piperazinyl)methyl]benzamide; N-[2-Methyl-5-[[4-[(4-methylpiperazin-1-yl)methyl]benzoyl]amino]phenyl]guanidine. CAS No. 581076-65-5. Pack Sizes: 100 mg. Product ID: B2694-257315. Molecular formula: C21H28N6O. Mole weight: 380.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib Impurity C | an impurity of Imatinib (Gleevec). Group: Pharmaceutical. Alternative Names: Imatinib (Piperidine)-1-oxide; 4-[(4-Methyl-1-oxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. CAS No. 938082-57-6. Pack Sizes: 10 mg. Product ID: B2694-473162. Molecular formula: C29H31N7O2. Mole weight: 509.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib Impurity E | an impurity of Imatinib (Gleevec). Group: Pharmaceutical. Alternative Names: Des(methylpiperazinyl-N-methyl) Imatinib Dimer Impurity; 4,4'-(piperazine-1,4-diylbis(methylene))bis(N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide). CAS No. 1365802-18-1. Pack Sizes: 10 mg. Product ID: B2694-473163. Molecular formula: C52H48N12O2. Mole weight: 873.04. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib Impurity M | An impurity of Imatinib, a tyrosine kinase inhibitor used as a chemotherapy drug for the treatment of leukemia and other kinds of cancer. Group: Pharmaceutical. Alternative Names: 1,4-Bis(4-carboxybenzyl)-1-methylpiperazin-1-ium (Imatinib Impurity); 1,4-BIS(4-CARBOXYBENZYL)-1-METHYLPIPERAZIN-1-IUM; Imatinib Impurity M; SCHEMBL14646970; CS-0255288; F83280. CAS No. 1407229-73-5. Pack Sizes: 25 mg. Product ID: B2694-104820. Molecular formula: C21H25N2O4+. Mole weight: 369.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib mesylate | Imatinib (INN), marketed by Novartis as Gleevec (Canada, South Africa and the USA) or Glivec (Australia, Europe and Latin America), and sometimes referred to by its investigational name STI-571, is a tyrosine-kinase inhibitor used in the treatment of multiple cancers, most notably Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML). Group: Pharmaceutical. Alternative Names: CGP-57148B; CGP 57148B; CGP57148B; Gleevec, Imatinib. CAS No. 220127-57-1. Pack Sizes: 10 g. Product ID: NP3279. Molecular formula: C29H31N7O.CH4SO3. Mole weight: 589.71. Custom synthesis is available. Send your inquiries for more information. | London |
| Imatinib Related Substance B | An impurity of Imatinib, a tyrosine kinase receptor inhibitor used for cancer therapy. Group: Pharmaceutical. Alternative Names: Imatinib (Piperidine)-N,N-dioxide; 4-[(4-Methyl-1,4-dioxido-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. CAS No. 571186-93-1. Pack Sizes: 5 mg. Product ID: B2694-473161. Molecular formula: C29H31N7O3. Mole weight: 525.62. Custom synthesis is available. Send your inquiries for more information. | London |
| IMD 0354 | IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κβ pathway. Group: Pharmaceutical. Alternative Names: IMD-0354; IMD 0354; IMD0354. CAS No. 978-62-1. Pack Sizes: 50 mg. Product ID: B2693-383149. Molecular formula: C15H8ClF6NO2. Mole weight: 383.674. Custom synthesis is available. Send your inquiries for more information. | London |
| iMDK | iMDK is an inhibitor of midkine (MDK) expression, a growth factor commonly expressed in malignant tumors. iMDK dose-dependently inhibits MDK expression to attenuate certain tumor cell growth. It inhibits PI3K/Akt pathway thus induces apoptosis in MDK-expressing H441 lung adenocarcinoma cells. Uses: Antitumor agent. Group: Pharmaceutical. Alternative Names: 3-[2-(4-fluorobenzyl)imidazo[2,1-b][1,3]thiazol-6-yl]-2H-chromen-2-one. CAS No. 881970-80-5. Pack Sizes: 25 mg. Product ID: B1370-055117. Molecular formula: C21H13FN2O2S. Mole weight: 376.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Imeglimin hydrochloride | Imeglimin hydrochloride is the first in a new tetrahydrotriazine-containing class of oral antidiabetic agents, the glimins. It has been shown to act on the liver, muscle and pancreatic β-cells to uniquely target the key defects of type 2 diabetes. Group: Pharmaceutical. Alternative Names: EMD 387008 hydrochloride; EMD387008 hydrochloride; EMD-387008 hydrochloride. CAS No. 775351-61-6. Pack Sizes: 25 mg. Product ID: B2693-463327. Molecular formula: C6H14ClN5. Mole weight: 191.7. Custom synthesis is available. Send your inquiries for more information. | London |
| Imetelstat | Imetelstat is a telomerase inhibitor, also a synthetic lipid-conjugated, 13-mer oligonucleotide N3' P5'-thio-phosphoramidate with potential antineoplastic activity. Complementary to the template region of telomerase RNA (hTR), imetelstat acts as a competitive enzyme inhibitor that binds and blocks the active site of the enzyme (a "telomerase template antagonist"), a mechanism of action which differs from that for the antisense oligonucleotide-mediated inhibition of telomerase activity through telomerase mRNA binding. Inhibition of telomerase activity in tumor cells by imetelstat results in telomere shortening, which leads to cell cycle arrest or apoptosis. Group: Pharmaceutical. Alternative Names: Rytelo; GRN163L. CAS No. 868169-64-6. Pack Sizes: 1 mg. Product ID: B1370-462541. Custom synthesis is available. Send your inquiries for more information. | London |
| Imidapril HCl | Imidapril HCl is an ACE inhibitor used as an antihypertensive drug and for the treatment of chronic heart failure. Group: Pharmaceutical. CAS No. 89396-94-1. Pack Sizes: 50 mg. Product ID: B2693-401715. Molecular formula: C20H27N3O6·HCl. Mole weight: 441.91. Custom synthesis is available. Send your inquiries for more information. | London |
| Imidazo[1,2-b]pyridazine | Imidazo[1,2-b] pyridazine, a heterocyclic compound, plays a crucial role in the research and development of novel anti-neoplastic agents. Its mechanism of action involves selective enzyme inhibition, highlighting its potential as a therapeutic candidate for a wide spectrum of malignancies. Group: Pharmaceutical. CAS No. 766-55-2. Pack Sizes: 1mg;1g;10g. Product ID: NP3189. Molecular formula: C6H5N3. Mole weight: 119.12. Custom synthesis is available. Send your inquiries for more information. | London |
| Imidazole | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Group: Pharmaceutical. Alternative Names: Ondansetron EP Impurity E; Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene; 1,3-Diazole; 3-Azapyrrole; Curezol SIZ; Glyoxalin; Imidazol; Imutex; Methanimidamide, N,N'-1,2-ethenediyl-; Miazole. CAS No. 288-32-4. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008116. Molecular formula: C3H4N2. Mole weight: 68.08. Custom synthesis is available. Send your inquiries for more information. | London |
| Imidocarb | Imidocarb, a synthetic derivative of carbanilide, is a potent medication employed in the eradication of parasitic infections notably induced by Babesia and Trypanosoma organisms. This pharmacological agent is a primary choice in veterinary therapeutics for combating afflictions including babesiosis and theileriosis in diverse animal species. Group: Pharmaceutical. Alternative Names: IMIDOCARB; 1,3-Bis[3-(4,5-dihydro-1H-imidazol-2-yl)-phenyl]urea; 3,3'-di-2-imidazolin-2-yl-carbanilid; n,n'-bis(3-(4,5-dihydro-1h-imidazol-2-yl)phenyl)-ure; n,n'-bis(3-(4,5-dihydro-1h-imidazol-2-yl)phenyl)urea; N,N'-Bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]. CAS No. 27885-92-3. Pack Sizes: 1mg;1g;10g. Product ID: 27885-92-3. Molecular formula: C19H20N6O. Mole weight: 348.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Imidocarb-[d8] dihydrochloride | Labelled Imidocarb 2HCl. Imidocarb 2HCl is a salt form of Imidocarb, which is a derivative of urea used as an antiprotozoal agent in the veterinary drug. Group: Pharmaceutical. Pack Sizes: 25 mg. Product ID: BLP-008861. Molecular formula: C19H14D8Cl2N6O. Mole weight: 429.37. Custom synthesis is available. Send your inquiries for more information. | London |
| Imipenem Monohydrate | Imipenem is an intravenous β-lactam antibiotic. It is the first member of the carbapenem class of antibiotics. Imipenem is discovered via a lengthy trial-and-error search for a more stable version of the natural product thienamycin, which is produced by the bacterium Streptomyces cattleya. Imipenem has a broad spectrum of activity against aerobic and anaerobic, Gram-positive and Gram-negative bacteria. It is particularly important for its activity against Pseudomonas aeruginosa and the Enterococcus species, but it is not active against MRSA. Uses: Anti-bacterial agents. Group: Pharmaceutical. Alternative Names: (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, monohydrate; N-Formimidoyl Thienamycin; MK-787; MK 787; MK787. CAS No. 74431-23-5. Pack Sizes: 500 mg. Product ID: BBF-04641. Molecular formula: C12H17N3O4S.H2O. Mole weight: 317.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Imiquimod-[d9] | Imiquimod-[d9] is a detuterated Imiquimod. Imiquimod is a medication of the immune response modifier class for the treatment of genital warts, superficial basal cell carcinoma, and actinic keratosis. Group: Pharmaceutical. Alternative Names: Imiquimod-d9; 1-(2-(methyl-d3)propyl-1,1,2,3,3,3-d6)-1H-imidazo[4,5-c]quinolin-4-amine; 4-amino-1-isobutyl-1h-imidazo[4,5-c]quinoline-d9. CAS No. 2712126-48-0. Pack Sizes: 5 mg. Product ID: BLP-014125. Molecular formula: C14H7N4D9. Mole weight: 249.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Imiquimod Related Compound B | A pharmacologically active compound related to Imiquimod, a toll-like receptor 7 agonist used as an immune response modifier. Group: Pharmaceutical. Alternative Names: Desamino Imiquimod N-Oxide; 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinoline 5-Oxide; 1-Isobutyl-1H-imidazo[4,5-c]quinoline N-Oxide; USP Imiquimod Related Compound B. CAS No. 99010-63-6. Pack Sizes: 1 g. Product ID: B1370-473222. Molecular formula: C14H15N3O. Mole weight: 241.3. Custom synthesis is available. Send your inquiries for more information. | London |
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