BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Isorhamnetin 3-glucoside-7-rhamnoside | Isorhamnetin 3-glucoside-7-rhamnoside is a compound of the flavonoid class found in the herbs of Hippophae rhamnoides Linn. Group: Pharmaceutical. CAS No. 17331-71-4. Pack Sizes: 5 mg. Product ID: B0005-241930. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Isorhamnetin-3-O-galactoside | Isorhamnetin-3-O-galactoside, an indigenous flavonoid constituent obtained through extraction from spinach and onions, has been documented to exhibit substantial antioxidative and anti-inflammatory properties, evincing prospects as a therapeutic agent in diverse ailments encompassing malignancy, diabetes, and Alzheimer's. Group: Pharmaceutical. CAS No. 6743-92-6. Pack Sizes: 5 mg. Product ID: B2705-001590. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isorhamnetin 3-O-glucoside | Isorhamnetin-3-O-beta-D-Glucoside is a glycosyloxyflavone found in many vegetables. Uses: For the prevention and/or treatment of diabetes and its complications. Group: Pharmaceutical. CAS No. 5041-82-7. Pack Sizes: 5 mg. Product ID: NP1954. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isorhamnetin 3-sophoroside-7-rhamnoside | Isorhamnetin 3-sophoroside-7-rhamnoside is a compound of the flavonoid class found in the herbs of Elaeagnus multiflora Thunb. Group: Pharmaceutical. CAS No. 41328-75-0. Pack Sizes: 5 mg. Product ID: B0005-001591. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isorhamnetin 7-O-α-L-rhamnoside | Isorhamnetin 7-O-α-L-rhamnoside is a compound of the flavonoid class found in the herbs of Elaeagnus multiflora Thunb. Group: Pharmaceutical. CAS No. 17331-72-5. Pack Sizes: 2 mg. Product ID: B0005-053555. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isorhynchophylline | Rhynchophylline and isorhynchophylline act as noncompetitive antagonists of the NMDA receptor and that this property may contribute to the neuroprotective and anticonvulsant activity of the Uncaira species plant extracts. Rhynchophylline and isorhynchophylline have a non-competitive antagonistic effect on the NMDA-type ionotropic glutamate receptors, the present results suggest that these alkaloids exert their protective action against ischemia-induced neuronal damage by preventing NMDA, muscarinic M1, and 5-HT2 receptors-mediated neurotoxicity during ischemia. Group: Pharmaceutical. CAS No. 6859-1-4. Pack Sizes: 50 mg. Product ID: NP0065. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isosalvipuberulin | Isosalvipuberulin can be isolated from the aerial parts of Salvia dugesii. Group: Pharmaceutical. CAS No. 115321-32-9. Pack Sizes: 5 mg. Product ID: NP1594. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isosativan | Isosativan is a natural flavanone isolated from the herbs of Trifolium pratense L. Group: Pharmaceutical. CAS No. 60102-29-6. Pack Sizes: 1 mg. Product ID: NP2177. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isoscoparin | Isoscoparin is a compound of the flavonoid class found in the seeds of Alliaria petiolata with antioxidant activity. Isoscoparin is promisingly used in the treatment of obesity for its anti-adipogenic property. Group: Pharmaceutical. CAS No. 20013-23-4. Pack Sizes: 5 mg. Product ID: B0005-454692. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isoscoparin-2"-β-D-glucopyranoside | Isoscoparin-2"-β-D-glucopyranoside is a compound of the flavonoid class found in the seeds of Alliaria petiolata. Group: Pharmaceutical. CAS No. 97605-25-9. Pack Sizes: 5 mg. Product ID: B0005-053552. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isosilybin A | Isosilybin A is a flavonoid found in Silybum marianum. Isosilybin A has been identified as the first flavonolignan PPAR-gamma agonist. Group: Pharmaceutical. CAS No. 142796-21-2. Pack Sizes: 10 mg. Product ID: B2703-362207. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isosorbide Impurities | Isosorbide Impurities play a crucial role in the development and manufacturing of cardiovascular drugs, specifically those treating angina pectoris. Understanding these impurities facilitates improved drug formulation and safety assessment, ensuring enhanced therapeutic efficacy and patient compliance in managing heart-related conditions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isosteviol | Isosteviol is a tetracyclic diterpenoid with a beyerane core. It can exhibit antihypertensive activity, reduce blood glucose, suppress cancer cells. Group: Pharmaceutical. CAS No. 27975-19-5. Pack Sizes: 100 mg. Product ID: NP1538. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isotaxiresinol | Isotaxiresinol is a natural lignan found in the branch of Taxus wallichiana. Isotaxiresinol is useful for the treatment of postmenopausal osteoporosis, especially for prevention of bone fracture induced by estrogen deficiency. Uses: Anti-cancer; anti-osteoporosis. Group: Pharmaceutical. CAS No. 26194-57-0. Pack Sizes: 1 mg. Product ID: NP3924. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ISOTETRANDRINE | Isotetrandrine is isolated from the roots of Stephania tetrandra S.Moore. Uses: Antineoplastic; anti-inflammatory; antihypertensive; antibacterial. Group: Pharmaceutical. CAS No. 477-57-6. Pack Sizes: 1 mg. Product ID: NP0082. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isotetrandrine N-2'-oxide | Isotetrandrine N-2'-oxide is isolated from the roots of Stephania tetrandra S.Moore. Group: Pharmaceutical. CAS No. 70191-83-2. Pack Sizes: 1 mg. Product ID: NP0134. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isothiazolinone Impurities | Isothiazolinone Impurities, serving as fundamental analytical standards, occupy a critical niche in the biomedical realm for assessing antimicrobial agent purity and efficacy, especially in dermatological infection treatments. They assist in identifying and mitigating possible adverse interactions associated with isothiazolinone compounds, thus enhancing the safety protocols of skin therapies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isothymusin | Isothymusin is isolated from the herbs of Limnophila geoffrayi. It exhibits inhibitory activity against Mycobacterium tuberculosis. Uses: Antioxidant activity; antimycobacterial. Group: Pharmaceutical. CAS No. 98755-25-0. Pack Sizes: 5 mg. Product ID: NP2134. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isovaline | Isovaline. Group: Pharmaceutical. CAS No. 465-58-7. Pack Sizes: 5 g. Product ID: B1370-023218. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isoverticine | Isoverticine is found in Fritillaria monantha. Group: Pharmaceutical. CAS No. 23496-43-7. Pack Sizes: 10 mg. Product ID: B2703-334739. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isovitexin | Isovitexin, a food phytochemical contained in dietary rice products, or as a natural plant flavonoid isolated from the seeds of Vitex trifolia L, suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages. Isovitexin exhibits anti-inflammatory and anti-oxidant activities on lipopolysaccharide-induced acute lung injury by inhibiting MAPK and NF-κB and activating HO-1/Nrf2 pathways. Isovitexin can inhibit xanthine oxidase with an IC50 value of 15.2 microM, and it may protect cells from oxidative stress. Group: Pharmaceutical. CAS No. 29702-25-8. Pack Sizes: 100 mg. Product ID: NP1807. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isovitexin 2''-O-arabinoside | Isovitexin 2''-O-arabinoside is a compound of the flavonoid class found in the leaves of Secale cereale. Group: Pharmaceutical. CAS No. 53382-71-1. Pack Sizes: 5 mg. Product ID: B0005-053548. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isoxanthohumol | Isoxanthohumol is a derivative of xanthohumol in the flavonoids class. It is isolated from the the roots of Sophora flavescens Ait. Isoxanthohumol exhibits antioxidant, anti-inflammatory and antiangiogenic properties. Isoxanthohumol induces apoptosis in mature adipocytes, and inhibits differentiation of preadipocytes. Group: Pharmaceutical. CAS No. 70872-29-6. Pack Sizes: 100 mg. Product ID: NP1955. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ispinesib | Ispinesib is a synthetic small molecule, derived from quinazolinone, with antineoplastic properties. Ispinesib selectively inhibits the mitotic motor protein, kinesin spindle protein (KSP), resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and cell death in tumor cells that are actively dividing. Because KSP is not involved in nonmitotic processes, such as neuronal transport, ispinesib may be less likely to cause the peripheral neuropathy often associated with the tubulin-targeting agents. Group: Pharmaceutical. CAS No. 336113-53-2. Pack Sizes: 50 mg. Product ID: B0084-066412. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isradipine | Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure. Group: Pharmaceutical. CAS No. 75695-93-1. Pack Sizes: 500 mg. Product ID: B2692-076559. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isradipine Impurities | Isradipine Impurities, integral in the biomedical sector, are vital for assessing the purity of the antihypertensive drug Isradipine. These impurities are crucial for analytical studies to ensure drug safety and efficacy, facilitating the development of treatments for hypertension and associated cardiovascular disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ISRIB | ISRIB is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Group: Pharmaceutical. CAS No. 1597403-47-8. Pack Sizes: 250 mg. Product ID: BAT-010737. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ISRIB (mix-Isomer) | ISRIB (mix-Isomer), is a symmetric bis-glycolamide that inhibits integrated stress response (ISR). In wild-type mice studies has shown that it improved memory by efficiently reversing the effects of eIF2α phosphorylation, which has brought expectation that inhibition of PERK signaling may have the potential to ameliorate Alzheimer's disease. In a present study ISRIB demonstrated to attenuate amyloid b-induced neuronal cell death although the pharmacological mechanisms of this action have not yet been elucidated. Group: Pharmaceutical. CAS No. 548470-11-7. Pack Sizes: 25 mg. Product ID: BAT-010736. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Istradefylline | Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist (Ki=2.2 nM). Uses: Adenosine a2 receptor antagonists. Group: Pharmaceutical. CAS No. 155270-99-8. Pack Sizes: 500 mg. Product ID: B0084-084866. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Istradefylline Impurities | Istradefylline Impurities hold a critical function in the qualitative assessment of Istradefylline, an adenosine A2A receptor antagonist targeting Parkinson's therapeutics. These impurities are vital in drug formulation and regulatory adherence, guaranteeing pharmaceutical integrity and the safety of medicinal products, thereby underpinning therapeutic efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| IT 901 | IT 901, a bioactive naphthalenethiobarbiturate derivative, potently inhibits the NF-κB subunit c-Rel with IC50 value of 3 μM. It shows its anticancer properties in Hematologic Malignancies by inhibiting the oxidative stress response in lymphoma cells. It suppressed graft-versus-host disease while preserving graft-versus-lymphoma activity during allogeneic transplantation. It did not elicit increased levels of reactive oxygen species in normal leukocytes, illustrating its cancer selective properties. It is used for the treatment of human B-cell lymphoma and reveals antitumor properties in vitro and in vivo. It is also a novel therapeutic agent to ameliorate graft-versus-host disease. Group: Pharmaceutical. CAS No. 1584121-99-2. Pack Sizes: 5 mg. Product ID: B0084-169649. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Itacitinib | Itacitinib is a potent and selective JAK1 inhibitor developed for the treatment of Graft-versus-host disease and non-small cell lung cancer. Group: Pharmaceutical. CAS No. 1334298-90-6. Pack Sizes: 10 mg. Product ID: B0084-474483. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ITE | ITE is an Aryl hydrocarbon receptor ligand that acts as an endogenous aryl hydrocarbon receptor (AhR) agonist (Ki = 3 nM). Uses: Endogenous aryl hydrocarbon receptor (ahr) agonist. Group: Pharmaceutical. CAS No. 448906-42-1. Pack Sizes: 100 mg. Product ID: B2693-142421. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ITI214 | ITI214 is a highly selective PDE1 inhibitor (Ki = 58 pM) at picomolar concentration without disrupting other PDE family members and a panel of enzymes, receptors, transporters, and ion channels. Group: Pharmaceutical. CAS No. 1642303-38-5. Pack Sizes: 100 mg. Product ID: B2693-474648. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Itol A | Itol A is a natural diterpenoid found in the herbs of Geranium wilfordii. Group: Pharmaceutical. CAS No. 1033747-78-2. Pack Sizes: 5 mg. Product ID: NP1231. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Itopride Impurities | Itopride Impurities are critical for ensuring drug safety and efficacy in treating gastrointestinal illnesses, including functional dyspepsia and gastroparesis. By identifying and quantifying these impurities, researchers enhance the pharmaceutical quality of Itopride, facilitating the development of more effective clinical treatments for related conditions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Itraconazole | Itraconazole, a triazole antifungal agent, is a relatively potent inhibitor of CYP3A4. Uses: Antifungal agents; antiprotozoal agents. Group: Pharmaceutical. CAS No. 84625-61-6. Pack Sizes: 50 g. Product ID: B0046-476797. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Itraconazole Impurities | Itraconazole Impurities hold paramount significance within the pharmaceutical sector, facilitating quality control for itraconazole, a potent antifungal utilized against fungal afflictions such as aspergillosis and onychomycosis. These impurities are instrumental in scrutinizing drug purity and stability, thereby safeguarding therapeutic safety and amplifying efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ivabradine hydrochloride | Ivabradine is a medication of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. It is used for the treatment of symptomatic management of stable heart-related chest pain and heart failure. Group: Pharmaceutical. CAS No. 148849-67-6. Pack Sizes: 5 g. Product ID: NP3530. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ivabradine Impurities | Ivabradine Impurities, crucial in the biomedical industry, are utilized in the analysis and quality control of Ivabradine, a heart rate-reducing agent. These impurities aid in ensuring the safety and efficacy of Ivabradine used to treat chronic stable angina and heart failure, enhancing therapeutic outcomes for patients. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ivabradine Impurity 15 | An impurity of Ivabradine, which is a novel heart rate lowering medication. It can slow the heart rate by hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Ivabradine is marketed under trade names including Coralan, Corlentor, Procoralan, Coraxan. Group: Pharmaceutical. CAS No. 1616710-50-9. Pack Sizes: 10 mg. Product ID: B2694-343856. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ivabradine R-Isomer HCl | The enantiomer of Ivabradine Hydrochloride. Ivabradine is a medication used to reduce the risk of hospitalization for worsening heart failure in adult patients with stable, symptomatic chronic heart failure. Group: Pharmaceutical. CAS No. 148849-68-7. Pack Sizes: 10 mg. Product ID: B2694-473454. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ivacaftor | Ivacaftor is a potentiator of CFTR targeting G551D-CFTR(EC50=100 nM)and F508del-CFTR(EC50=25 nM). Ivacaftor is used in the treatment of cystic fibrosis. Uses: Chloride channel agonists. Group: Pharmaceutical. CAS No. 873054-44-5. Pack Sizes: 1 g. Product ID: B0084-286767. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ivacaftor Impurities | Ivacaftor Impurities are crucial for ensuring the safety and efficacy of Ivacaftor, a medication used to treat cystic fibrosis caused by specific genetic mutations. They assist researchers in understanding and mitigating potential adverse effects, thus enhancing the drugs therapeutic profile and aiding in the development of more refined treatment strategies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ivermectin Impurities | Ivermectin Impurities, crucial in pharmaceutical research, play a significant role in ensuring the quality and efficacy of ivermectin, an antiparasitic drug. These impurities are meticulously analyzed to enhance ivermectin formulations, which are pivotal in treating parasitic infections such as onchocerciasis and lymphatic filariasis in humans. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ivosidenib | Ivosidenib is an oral inhibitor that specifically inhibits a mutated form of IDH1 in the cytoplasm, which blocks the proliferation of tumor cells expressing IDH1. Group: Pharmaceutical. CAS No. 1448347-49-6. Pack Sizes: 100 mg. Product ID: B0084-474585. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| IWR-1-endo | IWR-1-endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 value of 180 nM. Group: Pharmaceutical. CAS No. 1127442-82-3. Pack Sizes: 25 mg. Product ID: B0084-262341. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| IXA4 | IXA4 is a highly selective and non-toxic IRE1/XBP1s activator, which activates the IRE1/XBP1s signaling, regardless of the global activation of the unfolded protein response (UPR) or other stress-responsive signaling pathways, such as heat shock response or oxidative stress response. IXA4 reduces APP secretion by activating IRE1. IXA4 therapy improves systemic glucose metabolism and hepatic insulin action through IRE1-dependent liver transcriptomic remodeling, thereby reducing glucose production and steatosis. IXA4-stimulated IRE1 activation also enhances pancreatic function. Group: Pharmaceutical. CAS No. 1185329-96-7. Pack Sizes: 100 mg. Product ID: B1370-382267. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ixabepilone | Ixabepilone (also known as azaepothilone B, or BMS-247550) is an orally bioavailable microtubule inhibitor. Ixabepilone was a semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. Ixabepilone was approved in 2007. Group: Pharmaceutical. CAS No. 219989-84-1. Pack Sizes: 5 mg. Product ID: B0084-063099. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ixabepilone Impurities | Ixabepilone Impurities play a critical role in the pharmaceutical industry by ensuring the purity and efficacy of the anticancer drug Ixabepilone. These impurities are vital for quality control processes, helping to identify and measure unwanted by-products, thereby ensuring the safety and therapeutic effectiveness of oncological treatments for conditions like breast cancer. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ixazomib Citrate | The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM. Group: Pharmaceutical. CAS No. 1239908-20-3. Pack Sizes: 100 mg. Product ID: BBF-04173. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ixazomib Impurities | Ixazomib Impurities play a critical role in the quality control and characterization of Ixazomib, a proteasome inhibitor used primarily in treating multiple myeloma. Identifying and analyzing these impurities ensure the safety and efficacy of the drug, supporting ongoing research into proteasome-related cancer therapies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| J 147 | J 147, under the IUPAC name N- (2, 4-dimethylphenyl) -2, 2, 2-trifluoro-N-[ (E) - (3-methoxyphenyl) methylideneamino]acetamide, is a phenyl hydrazide compound that has been shown to prevent memory deficits in an Alzheimer's disease mouse model. in vitro: A potent neuroprotective and neurotrophic compound (EC50 = 25 - 200 nM) in vivo: Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus. Uses: Implicated in alzheimer's disease. Group: Pharmaceutical. CAS No. 1146963-51-0. Pack Sizes: 25 mg. Product ID: B0084-462708. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jaboticabin Impurities | Jaboticabin Impurities, essential to pharmaceutical inquiry, undergo rigorous assessment to determine jaboticabin-based therapeutics' purity and efficacy. These impurities aid in elucidating degradation pathways and enhancing drug formulation, significantly influencing therapeutic approaches for inflammation-related disorders and specific cancers, thus advancing medicinal safety and effectiveness. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jaceosidin | Jaceosidin is a natural flavonoid isolated from the herbs of Artemisia arctica. Jaceosidin exhibits the activities of anti-oxidative, anti-inflammatory and anti-neuroinflammation. Uses: Anti-oxidative, anti-inflammatory, anti-neuroinflammation. Group: Pharmaceutical. CAS No. 18085-97-7. Pack Sizes: 20 mg. Product ID: NP1915. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JANEX-1 | A cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (Janus family kinase 3; IC50 = 78 μM). Has no effect on JAK1, JAK2, or Zap/Syk or Src tyrosine kinases. Acts as a potent inhibitor of glioblastoma cell adhesion and migration. Also reported to block thrombin-induced platelet aggregation. Group: Pharmaceutical. CAS No. 202475-60-3. Pack Sizes: 50 mg. Product ID: B0084-211627. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jasminin | Jasminin is extracted from the leaves of Jasminum primulinum HEMSL. It tastes bitter. Group: Pharmaceutical. CAS No. 30164-93-3. Pack Sizes: 1 mg. Product ID: NP3832. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jatrophane 2 | Jatrophane 2 can be found in the branches of Jatropha carcas L. Group: Pharmaceutical. CAS No. 210108-86-4. Pack Sizes: 1 mg. Product ID: NP1704. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jatrophane 3 | Jatrophane 3 can be found in the branches of Jatropha carcas L. Group: Pharmaceutical. CAS No. 210108-87-5. Pack Sizes: 1 mg. Product ID: NP1597. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jatrophane 4 | Jatrophane 4 comes from the branches of Jatropha carcas L. Group: Pharmaceutical. CAS No. 210108-88-6. Pack Sizes: 1 mg. Product ID: NP1705. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jatrophane 5 | Jatrophane 5, coming from the branches of Jatropha carcas L, demonstrated the most powerful inhibition of P-gp, higher than R(+)-verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR). Group: Pharmaceutical. CAS No. 210108-89-7. Pack Sizes: 1 mg. Product ID: NP1305. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jatrorrhizine hydrochloride | Jatrorrhizine Hydrochloride (JH), an active component of the traditional Chinese medicinal herb Coptis chinensis, inhibited the proliferation and neovascularization of C8161 human metastatic melanoma cells. The effective inhibitory effects of Jatrorrhizine Hydrochloride on metastatic melanoma cell proliferation and neovascularization with low toxicity suggest that Jatrorrhizine Hydrochloride is a potential new antimelanoma drug candidate. Group: Pharmaceutical. CAS No. 6681-15-8. Pack Sizes: 10 mg. Product ID: B2703-464658. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JD-5037 | Jd-5037 is a peripherally-restricted cannabinoid inverse agonist at CB1 receptors that can be used as an anti-obesity drug, with a 700-fold higher affinity compared to CB2 receptors. Group: Pharmaceutical. CAS No. 1392116-14-1. Pack Sizes: 25 mg. Product ID: B0084-485448. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JE-2147 | JE-2147 is a dipeptide HIV protease inhibitor (PI) that is effective against a wide spectrum of HIV-1, HIV-2, simian immunodeficiency virus, and various clinical HIV-1 strains in vitro. Group: Pharmaceutical. CAS No. 186538-00-1. Pack Sizes: 10 mg. Product ID: B2693-008706. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jervine | Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling. It is an inhibitor of Smo and derived from the Veratrum plant species. Jervine can be used to induce abnormal morphogenesis in a number of experimental models. Uses: Antibacterial. Group: Pharmaceutical. CAS No. 469-59-0. Pack Sizes: 20 mg. Product ID: B2703-118799. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JHU37160 | JHU37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist. It has high affinity in vitro for hM3Dq and hM4Di (Ki values are 1.9 nM (hM3Dq) and 3.6 nM (hM4Di). Group: Pharmaceutical. CAS No. 2369979-68-8. Pack Sizes: 10 mg. Product ID: B2693-381543. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jinflexin A | Jinflexin A is a remarkable and potent pharmacological natural compound, finding extensive application for studying various ailments such as rheumatoid arthritis, osteoarthritis and diverse inflammatory joint disorders. This multifaceted natural compound exerts its mechanism of action via the proficient inhibition of pro-inflammatory cytokine production. Group: Pharmaceutical. CAS No. 2055155-75-2. Pack Sizes: 1 mg. Product ID: NP5010. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JK-184 | JK-184 is a potent downstream hedgehog (Hh) signaling antagonist that functions by alcohol dehydrogenase 7 (Adh7) inhibition, preventing Gli-dependent transcriptional activity (IC50 = 30 nM). Hedgehog signaling plays a key role in a wide variety of developmental processes as well as cancer progression. JK-184 exhibits antiproliferative activity. Uses: Differentiation. Group: Pharmaceutical. CAS No. 315703-52-7. Pack Sizes: 100 mg. Product ID: B2693-462944. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JK-P3 | JK-P3 is a VEGFR2 inhibitor with IC50 values of 7.8 μM. JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but exhibits no effect on FGFR signaling in cell-based assays. It suppresses wound healing and tube formation in HUVEC without effecting endothelial cell proliferation. Group: Pharmaceutical. CAS No. 942655-44-9. Pack Sizes: 25 mg. Product ID: B0084-284855. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JMV 449 | JMV 449 could be a neurotensin receptor agonist peptide and has been found to show hypothermic and analgesic activities in the mouse. Group: Pharmaceutical. CAS No. 139026-66-7. Pack Sizes: 10 mg. Product ID: BAT-010717. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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