BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| JNJ 0966 | JNJ 0966 is a selective inhibitor of MMP-9 (IC50 = 440 nM) with no effect on MMP-1, MMP-2, MMP-3, MMP-9, or MMP-14 catalytic activity. JNJ 0966 was indicated to alleviate the pain of experimental autoimmune encephalomyelitis in a mouse model. Group: Pharmaceutical. CAS No. 315705-75-0. Pack Sizes: 1 g. Product ID: B2693-291173. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| JNJ-26483327 | JNJ-26483327 is an orally bioavailable, small-molecule, multitargeted reversible tyrosine kinase inhibitor with potential antineoplastic activity. Multitargeted tyrosine kinase inhibitor JNJ-26483327 binds to and inhibits several members of the epidermal growth factor receptor (EGFR) family, including EGFR, HER2 and HER4; Src family kinases (Lyn, Yes, Fyn, Lck and Src); and vascular endothelial growth factor receptor type 3 (VEGFR3). By inhibiting several different signaling molecules that play crucial roles at various stages in tumorigenesis, this agent may inhibit tumor growth, invasion, migration and metastasis. In addition, JNJ-26483327 crosses the blood-brain barrier (BBB). Group: Pharmaceutical. CAS No. 807640-87-5. Pack Sizes: 10 mg. Product ID: B0084-462547. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JNJ 303 | JNJ 303 has been found to be a potent IKs blocker (IC50 = 64 nM) as well as a 11β-HSD1 inhibitor. Group: Pharmaceutical. CAS No. 878489-28-2. Pack Sizes: 100 mg. Product ID: B2693-129510. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JNJ-40411813 | JNJ-40411813 is a novel positive allosteric modulator of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM. Group: Pharmaceutical. CAS No. 1127498-03-6. Pack Sizes: 5 mg. Product ID: B2693-463522. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JNJ-42165279 | JNJ-42165279 is a fatty acid amide hydrolase (FAAH) inhibitor developed by Janssen Pharmaceutica and IC50 value is 70 nM. It is described as a covalently binding but slowly reversible selective inhibitor of FAAH. Phase II human trials for the treatment of anxiety disorders and major depressive disorder is on-going. Uses: Anxiety disorders and major depressive disorder. Group: Pharmaceutical. CAS No. 1346528-50-4. Pack Sizes: 10 mg. Product ID: B0084-470836. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JNJ 63533054 | JNJ 63533054 is a potent and selective GPR139 agonist (EC50 = 16 nM) that is brain and cell penetrant. JNJ 63533054 is selective for GPR139 over a panel of GPCRs, ion channels and transporters, including GPR142. Group: Pharmaceutical. CAS No. 1802326-66-4. Pack Sizes: 200 mg. Product ID: B0084-470901. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JNK-IN-8 | JNK-IN-8 inhibits c-Jun phosphorylation in HeLa and A375 cells with EC50 of 486 nM and 338 nM, respectively. Uses: Protein kinase inhibitors. Group: Pharmaceutical. CAS No. 1410880-22-6. Pack Sizes: 20 mg. Product ID: B0084-463416. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JPH203 | JPH203 is a potent and selective L-type amino acid transporter 1 (LAT1) inhibitor. It inhibits 14C-leucine uptake and cell growth in human colon cancer-derived HT-29 cells in vitro. It also inhibits 14C-leucine uptake in mouse renal proximal tubule cells expressing l-type amino acid transporter 1, and inhibits cell growth. It completely inhibits the proliferation of YD-38 cells in a dose- and time-dependent manner. It suppresses proliferation in cancer cell lines and is used for cancer research. It was developed by J-Pharma and in clinic phase 1 trials. Uses: Jph203 suppresses proliferation in cancer cell lines and is used for cancer research. Group: Pharmaceutical. CAS No. 1037592-40-7. Pack Sizes: 10 mg. Product ID: B0084-474997. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (+)-JQ-1 | (+)-JQ-1 is a potent and selective BET bromodomain inhibitor, IC50 values are 77 nM and 33 nM for inhibiting BRD4 (N-terminal) and BRD4 (C-terminal), respectively. Group: Pharmaceutical. CAS No. 1268524-70-4. Pack Sizes: 50 mg. Product ID: B0084-453787. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (+)-JQ1 carboxylic acid | (+)-JQ1 carboxylic acid is the carboxylic acid form of BET bromodomain inhibitor (+)-JQ1. Group: Pharmaceutical. CAS No. 202592-23-2. Pack Sizes: 100 mg. Product ID: B2693-474681. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JTE-013 | JTE-013 is a potent and selective sphingosine-1-phosphate (S1P) receptor 2 (S1P2) antagonist (IC50=17.6 nM). Group: Pharmaceutical. CAS No. 383150-41-2. Pack Sizes: 25 mg. Product ID: B0084-371711. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Jujuboside A | Jujuboside A may serve as a potential therapeutic agent for the treatment of Alzheimer?s disease. Uses: Therapeutic agent. Group: Pharmaceutical. CAS No. 55466-04-1. Pack Sizes: 25 mg. Product ID: NP7220. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JUN68744 | JUN68744 is a useful peptide linker for synthesis of PSMA-617 (vipivotide tetraxetan), which is a ligand used to make 177Lu-PSMA-617, a radioactive molecule to fight cancer. PSMA-617 originally was developed at the German Cancer Research Center and the Heidelberg University Hospital. ABX held the exclusive license to bring the treatment, which targets prostate-specific membrane antigen (PSMA), through early clinical development. Group: Pharmaceutical. CAS No. 1703768-74-4. Pack Sizes: 100 mg. Product ID: BADC-00615. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Juncuenin D | Juncuenin D, an all-natural compound, boasts of its potent anti-inflammatory and anticancer properties. Research studies exhibit its capability to suppress leukemia cells' growth via selective cell cycle arrest. Furthermore, it showcases its therapeutic potential in terms of inflammatory diseases by impeding pro-inflammatory cytokine production. Its revolutionary features highlight its significance as a potential therapeutic agent with immense curative measures. Group: Pharmaceutical. CAS No. 1161681-24-8. Pack Sizes: 1 mg. Product ID: NP5004. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Juncusol | Juncusol is a 9,10-dihydrophrenathrene found in Juncus species with antimicrobial activity against Bacillus subtilis and Staphylococcus aureus. Group: Pharmaceutical. CAS No. 62023-90-9. Pack Sizes: 5 mg. Product ID: NP5120. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Juncutol | Juncutol, a topical antiseptic, exerts its antimicrobial effect through the active ingredient, povidone-iodine, which eradicates bacteria and other microorganisms that may cause infections in cuts, wounds, and burns. In addition to this primary indication, it has been employed for the management of chronic wounds, including diabetic foot ulcers. With its proven efficacy and safety profile, Juncutol is an indispensable tool in wound care. Group: Pharmaceutical. CAS No. 1021950-14-0. Pack Sizes: 1 mg. Product ID: NP5003. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JX 06 | JX 06 is a potent, selective and covalent pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor with IC50 values of 49, 101 and 313 nM for PDK1, PDK2 and PDK3, respectively. It suppresses A549 lung cancer cell proliferation in vitro and reduces tumor volume of A549 xenografts in mice. Group: Pharmaceutical. CAS No. 729-46-4. Pack Sizes: 500 mg. Product ID: B2693-169680. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| K03861 | K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. Group: Pharmaceutical. CAS No. 853299-07-7. Pack Sizes: 50 mg. Product ID: B0084-459880. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| K252A | K252a, an analog of staurosporine, has been found to be a protein kinase inhibitor and exhibit antitumor activity at some extent. Group: Pharmaceutical. CAS No. 99533-80-9. Pack Sizes: 50 mg. Product ID: BBF-04182. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| K-7174 dihydrochloride | K-7174, one of proteasome inhibitory homopiperazine derivatives, exhibits a therapeutic effect, which is stronger when administered orally than intravenously, without obvious side effects in a murine myeloma model. Moreover, K-7174 kills bortezomib-resistant myeloma cells carrying a β5-subunit mutation in vivo and primary cells from a patient resistant to bortezomib. Group: Pharmaceutical. CAS No. 191089-60-8. Pack Sizes: 100 mg. Product ID: B2693-463577. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferitrin | Kaempferitrin isolated from the root of Kaempferia galangal L. It stimulates glucose-metabolizing enzymes and promotes glucose homeostasis. Uses: Cytotoxic and antitumor effects; antidepressant-like effect; immunostimulatory effects. Group: Pharmaceutical. CAS No. 482-38-2. Pack Sizes: 20 mg. Product ID: NP1860. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol | Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources. It has many functions such as anti-cancer, diuretic, anti-inflammatory, antioxidant, anti-bacterial, and anti-virus. Kaempferol can be used in food additive. Uses: Anti-inflammatory; diuretic; antioxidant; inhibitor of topoisomerase-ii. Group: Pharmaceutical. CAS No. 520-18-3. Pack Sizes: 250 mg. Product ID: NP1821. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol 3-a-L-arabinopyranoside | Kaempferol 3-a-L-arabinopyranoside comes from the roots of Ligusticum jeholense Nakai et Kitag. Group: Pharmaceutical. CAS No. 99882-10-7. Pack Sizes: 5 mg. Product ID: NP1830. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol-3-Glucuronide | Kaempferol-3-beta-O-glucuronide is a flavonoid glucuronide, which can be found in vegetables and deconjugated by microsomal β-glucuronidase from various human cells. Uses: Antioxidant. Group: Pharmaceutical. CAS No. 22688-78-4. Pack Sizes: 10 mg. Product ID: B2703-001600. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol 3-O-(2''-O-glucosyl)rutinoside | Kaempferol-3-O-(2"-O-β-D- glucopyl)-β-D-rutinoside is a compound of the flavonoid class. Group: Pharmaceutical. CAS No. 55696-58-7. Pack Sizes: 5 mg. Product ID: NP2093. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol-3-O-α-L-rhamnopyranosyl-(1?6)-β-D-glucopyranosyl-(1?2)-β-D-glucopyranoside | Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside is found in Hosta plantaginea, it shows antioxidant activity. Group: Pharmaceutical. CAS No. 476617-49-9. Pack Sizes: 5 mg. Product ID: B1370-334820. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol 3-O-beta-(6''-p-coumaroyl) glucopyranosyl (1?2)-alpha-L-rhamnopyranoside | Kaempferol 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1→2)-alpha-L-rhamnopyranoside is a flavonoid and a natural antioxidant. Group: Pharmaceutical. CAS No. 111957-48-3. Pack Sizes: 5 mg. Product ID: B1370-334434. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol 3-O-sophoroside | Kaempferol 3-β-Sophoroside is a derivative of Kaempferol with antibacterial and antiviral activities. Group: Pharmaceutical. CAS No. 19895-95-5. Pack Sizes: 5 mg. Product ID: NP2493. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol 3-O-sophoroside-7-O-glucoside | Kaempferol 3-sophoroside-7-glucoside is a compound of the flavonoid class found in the stems of Equisetum hyemale L. Group: Pharmaceutical. CAS No. 55136-76-0. Pack Sizes: 5 mg. Product ID: NP2035. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol 3-sophoroside-7-rhamnoside | Kaempferol 3-sophoroside-7-rhamnoside is a compound of the flavonoid class found in the herbs of Elaeagnus multiflora Thunb. Group: Pharmaceutical. CAS No. 93098-79-4. Pack Sizes: 5 mg. Product ID: B0005-053545. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol 7,4'-dimethyl ether | 3,5-Dihydroxy-4',7-dimethoxyflavone is a natural flavonoid found in the herb of Andrographis paniculata (Burm. f.) Nees. Group: Pharmaceutical. CAS No. 15486-33-6. Pack Sizes: 5 mg. Product ID: NP2039. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol-7-O-glucoside | Kaempferol-7-O-β-D-glucopyranoside is extracted from the herbs of Hosta plantaginea. Group: Pharmaceutical. CAS No. 16290-07-6. Pack Sizes: 10 mg. Product ID: B0005-224057. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol 7-O-rhamnoside | Kaempferol 7-O-rhamnoside is isolated from the herbs of Maytenus hookeri. Group: Pharmaceutical. CAS No. 20196-89-8. Pack Sizes: 5 mg. Product ID: NP2003. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaempferol Impurities | Kaempferol Impurities are instrumental in the biomedical sector, functioning as reference benchmarks for the scrutiny and quality assurance of kaempferol-related pharmaceutical products. These impurities facilitate the assessment of kaempferol's purity, which is under exploration for therapeutic potential in addressing diverse inflammatory ailments and oncological conditions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaerophyllin | Kaerophyllin isolated from the roots of Bupleurum chinense DC. Group: Pharmaceutical. CAS No. 75590-33-9. Pack Sizes: 1 mg. Product ID: NP3941. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kajiichigoside F1 | Kajiichigoside F1 is a triterpenoid compound found in the roots of Rosa rugosa. Kajiichigoside F1 exhibits anti-inflammatory and hepatoprotective activities in vivo and antiviral activity in vitro. Group: Pharmaceutical. CAS No. 95298-47-8. Pack Sizes: 2 mg. Product ID: NP7062. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kallikrein Inhibitor | Kallikrein Inhibitor, a synthetic peptide, is a serine protease inhibitor that inhibits kallikrein and plasmin, and can attenuate breast cancer cell invasion. Group: Pharmaceutical. CAS No. 97145-43-2. Pack Sizes: 10 mg. Product ID: BAT-006188. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kalopanaxsaponin H | Kalopanaxsaponin H is extracted from the herbs of Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. It has antidiabetic activity. Group: Pharmaceutical. CAS No. 128730-82-5. Pack Sizes: 5 mg. Product ID: B0005-465767. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kanamycin Impurities | Kanamycin Impurities, integral to the biomedical sector, play a crucial role in quality control and assurance processes within kanamycin antibiotic production. These impurities are vital for evaluating the purity and safety of kanamycin formulations, ensuring effective treatment of bacterial infections, especially in tackling multidrug-resistant tuberculosis and other severe bacterial maladies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kanshone H | Kanshone H can be isolated from the rhizomes and roots of Nardostachys chinensis. Group: Pharmaceutical. CAS No. 1445952-33-9. Pack Sizes: 1 mg. Product ID: NP5870. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kansuinine A | Kansuinine A is extracted from the roots of Euphorbia kansui. It shows analgesic props and NGF inducing activity. Group: Pharmaceutical. CAS No. 57701-86-7. Pack Sizes: 1 mg. Product ID: NP1381. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Karakoline | Alkaloid , from plants of the Ranunculaceae family. Ganglioblocker; nicotinic receptor antagonist; hypotensive; presents micromolar affinity at brain a Bungarotoxin-sensitive nAChR. (See attached sheet.). Group: Pharmaceutical. CAS No. 39089-30-0. Pack Sizes: 20 mg. Product ID: B0005-115266. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kartogenin | Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the specific interaction between filamin A and CBFβ (core-binding factor β subunit). Apparently, kartogenin induces chondrogenesis by regulating the nuclear localization of CBF&beta. Group: Pharmaceutical. CAS No. 4727-31-5. Pack Sizes: 250 mg. Product ID: B0085-462283. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kaurenoic acid | Kaurenoic acid is a natural diterpenoid found in the herbs of Croton antisyphiliticus. Kaurenoic acid has anti-inflammatory activity, and also exhibits cytotoxic and embryotoxic effects. It acts through inhibition of iNOS and COX-2 expression. Uses: Anti-inflammatory. Group: Pharmaceutical. CAS No. 6730-83-2. Pack Sizes: 25 mg. Product ID: NP1523. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kazinol B | Kazinol B is a natural flavonoid found in the barks of Broussonetia papyrife. It has inhibition of nitric oxide production on LPS-activated macrophages and has inhibiion of SOCE. Group: Pharmaceutical. CAS No. 99624-27-8. Pack Sizes: 1 mg. Product ID: NP2014. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kazinol U | Kazinol U is one estrogenic found in Broussonetia kazinoki. Kazinoki may be useful in the treatment of menopausal symptoms and may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes. Group: Pharmaceutical. CAS No. 1238116-48-7. Pack Sizes: 1 mg. Product ID: NP2369. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KB-R7943 mesylate | KB-R7943 is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 μM). Group: Pharmaceutical. CAS No. 182004-65-5. Pack Sizes: 100 mg. Product ID: B1370-207121. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KD025 | KD025 is an orally available and selective ROCK2 inhibitor with IC50 value of 60 nM and Ki value of 41 nm, respectively. It was shown to suppress adipogenesis in human adipose-derived stem cells. Uses: Protein kinase inhibitors. Group: Pharmaceutical. CAS No. 911417-87-3. Pack Sizes: 100 mg. Product ID: B0084-460389. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KDM5-inhibitor | KDM5-inhibitor is an analog of CPI-455, a selective KDM5 inhibitor. CPI-455 increases levels of H3K4 trimethylation (H3K4me3) and decreases the number of DTPs in multiple cancer cell lines treated with standard chemotherapy or targeted agents. It reduces survival of drug-tolerant cancer cells. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B0084-284866. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kenpaullone | Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC50 = 400 nM), CDK2/cyclin A (IC50 = 680 nM), CDK2/cyclin E (IC50 = 7.5 uM) and CDK5/p25 (IC50 = 850 nM). Kenpaullone inhibits CDK2/cyclin A, CDK2/cyclin E and CDK5/cyclin/p35 (IC50 values are 0.68, 7.5 and 0.85 μM respectively). Uses: Reprogramming. Group: Pharmaceutical. CAS No. 142273-20-9. Pack Sizes: 100 mg. Product ID: B2693-350677. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kerantinocyte Growth Factor | Recombinant Human KGF is an 18.9 kDa protein containing 163 amino residues. Group: Pharmaceutical. CAS No. 148348-15-6. Pack Sizes: 50 mg. Product ID: B1370-167006. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ketoconazole EP Impurity C | Ketoconazole EP Impurity C is an impurity of Ketoconazole, which is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. Group: Pharmaceutical. CAS No. 83374-59-8. Pack Sizes: 5 mg. Product ID: B1270-120523. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ketoconazole Impurities | Ketoconazole Impurities, intricately examined within pharmaceutical domains, unveil essential data regarding drug safety and efficacy. Their critical presence is paramount in the meticulous scrutiny of ketoconazole-based formulations, ensuring regulatory adherence and therapeutic optimization, thereby enhancing treatment efficacies for fungal maladies such as candidiasis and dermatophytosis. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ketoprofen Impurities | Ketoprofen Impurities are vital in the biomedical industry for research and development of non-steroidal anti-inflammatory drugs (NSAIDs). These impurities help in understanding the pharmacokinetics, stability, and efficacy of ketoprofen, benefiting treatments for conditions like arthritis, pain, and inflammation-related disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ketorolac Impurities | Ketorolac Impurities, observed in the synthesis of ketorolac, play a crucial role in quality control and enhancement of anti-inflammatory and analgesic drug formulations. These impurities help researchers understand pharmacokinetics and ensure the efficacy and safety of ketorolac, widely used for treating postoperative pain and inflammation. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ketotifen Fumarate | Ketotifen is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis,or the itchy red eyes caused by allergies. In its oral form, it is used to preventasthma attacks. Uses: Antipruritics. Group: Pharmaceutical. CAS No. 34580-14-8. Pack Sizes: 5 g. Product ID: B0046-463927. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ketotifen Impurities | Ketotifen Impurities are crucial in the biomedical industry for evaluating the purity and quality of Ketotifen, an antihistamine used to treat asthma and allergic conditions. Understanding these impurities aids in ensuring the efficacy and safety of the drug while facilitating research into improved formulations and therapeutic outcomes. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ketotifen Impurity B | Ketotifen impurity, used in separation of enantiomers of Ketotifen and its polar intermediate by isotachophoresis. Group: Pharmaceutical. CAS No. 59743-88-3. Pack Sizes: 50 mg. Product ID: B1271-261956. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KGA2727 | KGA2727 is a selective and potent SGLT1 inhibitor for the treatment of diabete. Its inhibition constant (Ki) values of 97 and 13,600 nM for human (h) SGLT1 and hSGLT2 respectively. It inhibited the absorption of glucose but not that of fructose. Uses: Kga2727 is used for the treatment of diabete. Group: Pharmaceutical. CAS No. 666842-36-0. Pack Sizes: 50 mg. Product ID: B2693-476095. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ki20227 | Ki-20227 is a highly selective c-Fms tyrosine kinase(CSF1R) inhibitor. Group: Pharmaceutical. CAS No. 623142-96-1. Pack Sizes: 50 mg. Product ID: B0084-194510. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kimcuongin | Kimcuongin is a coumarin isolated from Murraya paniculata leaves that has the potential to be used as a vasodilator. Group: Pharmaceutical. CAS No. 1872403-23-0. Pack Sizes: 5 mg. Product ID: NP1200. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KIN1148 | KIN1148, a small-molecule IRF3 agonist, associates with and activates recombinant RIG-I protein in cell-free assays. KIN1148 is a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy. Group: Pharmaceutical. CAS No. 1428729-56-9. Pack Sizes: 100 mg. Product ID: B0084-007650. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KIRA6 | KIRA6 allosterically inhibits IRE1α RNase kinase activity in vivo and promotes cell survival under ER stress. Systemically, KIRA6 preserves pancreatic β cells, increases insulin, and reduces hyperglycemia in Akita diabetic mice. Group: Pharmaceutical. CAS No. 1589527-65-0. Pack Sizes: 20 mg. Product ID: B0084-007192. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KL-11743 | KL-11743 is a potent, orally active and glucose-competitive inhibitor of the class I glucose transporters, with IC50s of 115, 137, 90 and 68 nM for GLUT1, GLUT2, GLUT3 and GLUT4, respectively. It specifically blocks glucose metabolism and induces cell death in concert with electron transport inhibitors. Group: Pharmaceutical. CAS No. 1369452-53-8. Pack Sizes: 5 mg. Product ID: B2693-381869. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KNK437 | KNK437 is a pan-HSP inhibitor, which inhibits the synthesis of inducible HSPs, including HSP105, HSP72, and HSP40. Group: Pharmaceutical. CAS No. 218924-25-5. Pack Sizes: 50 mg. Product ID: B0084-470906. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kobusin | Kobusin is a lignan isolated from the barks of Zanthoxylum rhetsa that exhibits antiplasmodial and anti-inflammatory properties. Group: Pharmaceutical. CAS No. 36150-23-9. Pack Sizes: 5 mg. Product ID: NP4127. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Kongensin A | Kongensin A is isolated from the herbs of Croton cascarilloides. Group: Pharmaceutical. CAS No. 885315-96-8. Pack Sizes: 1 mg. Product ID: NP1337. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Koumine | Koumine has a significant analgesic effect in rodent behavioral models of inflammatory and neuropathic pain, and that the reduction in neuropathic pain may be associated with the upregulation of allopregnanolone in the spinal cord. Koumine has the potential to be a future breast cancer chemotherapeutic agent. Uses: Antineoplastic. Group: Pharmaceutical. CAS No. 1358-76-5. Pack Sizes: 25 mg. Product ID: NP0400. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Koumine N-oxide | Koumine N-oxide is an alkaloid compound found in the herbs of Gelsemium elegans. Group: Pharmaceutical. CAS No. 113900-75-7. Pack Sizes: 2 mg. Product ID: NP0109. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ku-0063794 | KU-0063794 is an inhibitor of both mTORC1 and mTORC2 with an IC50 of approximately 10 nM, but does not suppress the activity of 76 other protein kinases or seven lipid kinases, including Class 1 PI3Ks (phosphoinositide 3-kinases) at 1000-fold higher concentrations. KU-0063794 is cell permeant, suppresses activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK (ribosomal S6 kinase), an AGC kinase not regulated by mTOR. It also inhibited phosphorylation of the T-loop Thr308 residue of Akt phosphorylated by PDK1 (3-phosphoinositide-dependent protein kinase-1). It does not affect Thr308 phosphorylation in fibroblasts lacking essential mTORC2 subunits. KU-0063794 also suppressed cell growth and induced a G1-cell-cycle arrest. KU-0063794 will be useful in delineating the physiological roles of mTOR and may have utility in treatment of cancers in which this pathway is inappropriately activated. Uses: Differentiation. Group: Pharmaceutical. CAS No. 938440-64-3. Pack Sizes: 100 mg. Product ID: B0084-100850. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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