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Saponin. CAS No. 8047-15-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
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SAPONIN
SAPONIN. CAS No. 8047-15-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
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SAPONIN UN
SAPONIN UN, UK suppliers of laboratory chemicals wanted
Sappanchalcone
Sappanchalcone is a natural flavonoid extracted from Caesalpinia sappan. It exhibits cytoprotective activity and anti-inflammatory effects, which can reduce clinical arthritis. Sappanchalcone is also a xanthine oxidase inhibitor. Uses: Cytoprotective, anti-inflammatory. Group: Pharmaceutical. Alternative Names: (2E)-3-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-2-Methoxyphenyl)-2-propen-1-one; 3-(3,4-Dihydroxyphenyl)-1-(4-hydroxy-2-Methoxyphenyl)prop-2-en-1-one. CAS No. 94344-54-4. Pack Sizes: 5 mg. Product ID: NP0934. Molecular formula: C16H14O5. Mole weight: 286.3. Custom synthesis is available. Send your inquiries for more information.
London
Sapropterin dihydrochloride
Sapropterin is a naturally occurring cofactor for phenylalanine hydroxylase. Under the trade name Kuvan, sapropterin dihydrochloride is approved for the treatment of hyperphenylalaninaemia and tetrahydrobiopterin deficiency. Group: Pharmaceutical. Alternative Names: BioMarin T 1401; Biopten; Kuvan; SUN 0588; Shiratori SN 0588; (6R)-5,6,7,8-Tetrahydrobiopterin Dihydrochloride; Phenoptin; (R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one dihydrochloride; (6R)-Tetrahydrobiopterin hydrochloride; (6R)-5,6,7,8-Tetrahydro-L-Biopterin Dihydrochloride. CAS No. 69056-38-8. Pack Sizes: 500 mg. Product ID: B0046-097081. Molecular formula: C9H17Cl2N5O3. Mole weight: 314.17. Custom synthesis is available. Send your inquiries for more information.
London
Saquinavir mesylate
Saquinavir mesylate. CAS No. 149845-06-7. Product ID: C-23500.
CARBONE SCIENTIFIC UK
SAR-20347
SAR-20347 is a dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2) with IC50 values of 23 and 0.6 nM, respectively. It also exhibits slight inhibitory effects gainst JAK2 and JAK3. Group: Pharmaceutical. Alternative Names: 2-(2-Chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-4-oxazolecarboxamide; SAR 20347; SAR20347. CAS No. 1450881-55-6. Pack Sizes: 25 mg. Product ID: B0084-007837. Molecular formula: C21H18ClFN4O4. Mole weight: 444.84. Custom synthesis is available. Send your inquiries for more information.
London
SAR-405
SAR-405 is a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K) class III isoform Vps34 (IC50 = 1.2 nM, Kd=1.5 nM) without disrupting other PI3K isoforms and mTOR (IC50 > 10,000 nM). Concomitant inhibition of Vps34 and mTOR, with SAR405 and mTOR inhibitor everolimus, results in synergistic antiproliferative activity in renal tumor cell lines. Group: Pharmaceutical. Alternative Names: SAR 405; SAR405; 4H-Pyrimido[1,?2-a]?pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)?methyl]?-6,?7,?8,?9-tetrahydro-2-[(3R)?-3-methyl-4-morpholinyl]?-8-(trifluoromethyl)?-, (8S)?-; (8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one. CAS No. 1523406-39-4. Pack Sizes: 10 mg. Product ID: B2693-482215. Molecular formula: C19H21ClF3N5O2. Mole weight: 443.85. Custom synthesis is available. Send your inquiries for more information.
London
SAR7334
SAR7334, a TRPC6 inhibitor, could be valuable in studying sorts of diseases related to TRPC. Uses: Sar7334 is a trpc6 inhibitor that could be valuable in studying sorts of diseases related to trpc. Group: Pharmaceutical. Alternative Names: SAR7334; CPA1588; SAR 7334; CPA 1588; SAR-7334; CPA-1588; 4-(((1R,2R)-2-((R)-3-aminopiperidin-1-yl)-2,3-dihydro-1H-inden-1-yl)oxy)-3-chlorobenzonitrile; 1333207-63-8; 1333210-07-3; C21H22ClN3O. CAS No. 1333210-07-3. Pack Sizes: 5 mg. Product ID: B0084-474482. Molecular formula: C21H22ClN3O. Mole weight: 367.87. Custom synthesis is available. Send your inquiries for more information.
London
Saracatinib
Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival. Specifically, Saracatinib inhibits Src kinase-mediated osteoclast bone resorption. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: AZD 0530; AZD-0530; AZD0530. CAS No. 379231-04-6. Pack Sizes: 100 mg. Product ID: B0084-067564. Molecular formula: C27H32ClN5O5. Mole weight: 542.03. Custom synthesis is available. Send your inquiries for more information.
London
Sarafloxacin
Sarafloxacin is a quinolone antibiotic that inhibits bacterial DNA-topoisomerase II. It has been used in veterinary medicine. Group: Pharmaceutical. Alternative Names: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid. CAS No. 98105-99-8. Pack Sizes: 1mg;1g;10g. Product ID: 98105-99-8. Molecular formula: C20H17F2N3O3. Mole weight: 385.36. Custom synthesis is available. Send your inquiries for more information.
London
Sarafloxacin-[d8] Hydrochloride
Sarafloxacin-[d8] Hydrochloride is the labelled hydrochloride form of Sarafloxacin. Sarafloxacin is a quinolone antibiotic drug, inhibiting the topoisomerase II ligase domain. Group: Pharmaceutical. Alternative Names: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl-d8)-3-quinolinecarboxylic Acid Hydrochloride; A 56620-d8; PD 121960-d8; Sarafin-d8. CAS No. 1352879-52-7. Pack Sizes: 10 mg. Product ID: BLP-004197. Molecular formula: C20H10D8ClF2N3O3. Mole weight: 429.87. Custom synthesis is available. Send your inquiries for more information.
London
Sarafloxacin-[d8] hydrochloride hydrate
Sarafloxacin-[d8] hydrochloride hydrate is a labelled analogue of Sarafloxacin. Sarafloxacin is a topoisomerase II ligase inhibitor used as a quinolone antibiotic drug. Group: Pharmaceutical. Alternative Names: Sarafloxacin-D8 hydrochloride hydrate; Difloxacino-d8 hydrochloride hydrate; Difloxacinum-d8 hydrochloride hydrate; Sarafloxacino-d8 hydrochloride hydrate; Sarafloxacinum-d8 hydrochloride hydrate; 6-Fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazine-D8-1-yl-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate. Pack Sizes: 10 mg. Product ID: BLP-009155. Molecular formula: C20H9D8F2N3O3.HCl.H2O. Mole weight: 447.87. Custom synthesis is available. Send your inquiries for more information.
London
Sarafloxacin hydrochloride
Sarafloxacin hydrochloride. CAS No. 91296-87-6. Product ID: C-22090.
CARBONE SCIENTIFIC UK
Sarafloxacin hydrochloride
Sarafloxacin is a quinolone antibiotic drug, inhibiting the topoisomerase II ligase domain. It inhibits bacterial Topo II α (DNA gyrase, topoisomerase) and is effective against Mycobacterium tuberculosis. Group: Pharmaceutical. Alternative Names: Sarafloxacin HCl; A-56620; A 56620; A56620. CAS No. 91296-87-6. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03959. Molecular formula: C20H17F2N3O3.HCl. Mole weight: 421.83. Custom synthesis is available. Send your inquiries for more information.
London
Sarafotoxin S6c
Sarafotoxin S6c is a highly selective ETB endothelin receptor agonist (Ki = 0.29 and 28000 nM at ETB and ETA receptors, respectively). Uses: Vasoconstrictor agents. Group: Pharmaceutical. Alternative Names: Sarafotoxin C; S6C; H-Cys-Thr-Cys-Asn-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH (Disulfide bridge: Cys1-Cys15, Cys3-Cys11); L-cysteinyl-L-threonyl-L-cysteinyl-L-asparagyl-L-alpha-aspartyl-L-methionyl-L-threonyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-cysteinyl-L-leucyl-L-asparagyl-L-phenylalanyl-L-cysteinyl-L-histidyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide). CAS No. 121695-87-2. Pack Sizes: 1 mg. Product ID: BAT-015198. Molecular formula: C103H147N27O37S5. Mole weight: 2515.75. Custom synthesis is available. Send your inquiries for more information.
London
Saralasin
Saralasin is a competitive and nonselective angiotensin II receptor antagonist. Uses: Angiotensin ii type 1 receptor blockers. Group: Pharmaceutical. Alternative Names: (Sar1,Val5,Ala8)-Angiotensin II; Aralasin; Saralasinum. CAS No. 34273-10-4. Pack Sizes: 50 mg. Product ID: BAT-010131. Molecular formula: C42H65N13O10. Mole weight: 912.04. Custom synthesis is available. Send your inquiries for more information.
London
Sarcosine
Sarcosine. CAS No. 107-97-1. Product ID: C-33794.
CARBONE SCIENTIFIC UK
Sarcosine
Sarcosine is an endogenous GlyT1 inhibitor. Sarcosine displays antipsychotic activity and has the potential to treat schizophrenia. Sarcosine has been shown to potentiate the action of glycine on the NMDA glycine binding site. Uses: Sarcosine, also known as n-methylglycine, is a naturally occurring amino acid derivative that has shown promise in various areas including drug discovery and development. in recent years, there has been growing interest in exploring the pharmacological properties of sarcosine and its derivatives due to their diverse biological activities. sarcosine is a basic derivative of amino acids that is ess. Group: Pharmaceutical. Alternative Names: N-Methylglycine; Sarcosinic acid; Methylglycine; Glycine, N-methyl-. CAS No. 107-97-1. Pack Sizes: 1 kg. Product ID: BAT-008139. Molecular formula: C3H7NO2. Mole weight: 89.09. Custom synthesis is available. Send your inquiries for more information.
Sarecycline is a tetracycline antibiotic. It inhibits protein synthesis by binding to the 30S ribosomal subunit, thus preventing the attachment of amino acids to the elongating peptide chain. Group: Pharmaceutical. Alternative Names: Sarecycline free base; P-005672; P005672. CAS No. 1035654-66-0. Pack Sizes: 1mg;1g;10g. Product ID: 1035654-66-0. Molecular formula: C24H29N3O8. Mole weight: 487.51. Custom synthesis is available. Send your inquiries for more information.
London
Sarkosyl
Sarkosyl. CAS No. 137-16-6.
CARBONE SCIENTIFIC UK
Sarmentosin
Sarmentosin is isolated from the herb of Sedum sarmetosum Bunge. It shows a good effect in lowering serum glutamate-pyruvate transaminase and lowering the SGPT level of patients suffering from chronic viral hepatitis. It also shows a suppressive effect on cell-mediated immune responses in mice. Group: Pharmaceutical. Alternative Names: (2E)-4-(beta-D-Glucopyranosyloxy)-2-(hydroxymethyl)-2-butenenitrile. CAS No. 71933-54-5. Pack Sizes: 5 mg. Product ID: NP4346. Molecular formula: C11H17NO7. Mole weight: 275.3. Custom synthesis is available. Send your inquiries for more information.
London
Saroglitazar
Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity as a drug for the treatment of diabetic dyslipidemia and hypertriglyceridemia with Type 2 diabetes mellitus not controlled by statin therapy. Group: Pharmaceutical. Alternative Names: Lipaglyn; ZY-H1; (αS)-α-Ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]benzenepropanoic Acid. CAS No. 495399-09-2. Pack Sizes: 10 mg. Product ID: B1370-475759. Molecular formula: C25H29NO4S. Mole weight: 439.57. Custom synthesis is available. Send your inquiries for more information.
London
Sarolaner
Sarolaner is an antiparasitic agent. It is used as veterinary drug. Uses: Antiparasitic agent (veterinary use). Group: Pharmaceutical. Alternative Names: Simparica; PF-6450567; PF 6450567; PF6450567; (S)-1-(5'-(5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethan-1-one. CAS No. 1398609-39-6. Pack Sizes: 50 mg. Product ID: B1370-198584. Molecular formula: C23H18Cl2F4N2O5S. Mole weight: 581.37. Custom synthesis is available. Send your inquiries for more information.
London
SARPAGINE
Sarpagine is a natural alkaloid found in the roots of Alstonia yunnanensis Diels, it is effective in reversing multidrug-resistance (MDR) in vincristine-resistant KB cells. Group: Pharmaceutical. Alternative Names: Sarpagan-10,17-diol;Raupine;Sarpagane-10,17-diol. CAS No. 482-68-8. Pack Sizes: 1 mg. Product ID: NP0455. Molecular formula: C19H22N2O2. Mole weight: 310.4. Custom synthesis is available. Send your inquiries for more information.
London
Sarpogrelate-[d3] HCl
Sarpogrelate-[d3] HCl is a deuterated Sarpogrelate HCl. Sarpogrelate is a drug which acts as an antagonist at the 5HT2A and 5-HT2B receptors. Group: Pharmaceutical. Alternative Names: Sarpogrelate-d3 HCl; Sarpogrelate-D3 hydrochloride. Pack Sizes: 10 mg. Product ID: BLP-014091. Molecular formula: C24H29D3ClNO6. Mole weight: 468.99. Custom synthesis is available. Send your inquiries for more information.
London
Satraplatin
Satraplatin, also known as JM216, is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. It has not yet received approval from the U.S. Food and Drug Administration. First mentioned in the medical literature in 1993, satraplatin is the first orally active platinum-based chemotherapeutic drug; other available platinum analogues-cisplatin, carboplatin, and oxaliplatin-must be given intravenously. It is made available in the United States jointly by Spectrum Pharmaceuticals and GPC Biotech under the name SPERA (Satraplatin Expanded Rapid Access). The drug has also been used in the treatment of lung and ovarian cancers. The proposed mode of action is that the compound binds to the DNA of cancer cells rendering them incapable of dividing. Group: Pharmaceutical. Alternative Names: BMS-182751; BMS 182751; BMS182751; JM 216; JM216; JM-216. CAS No. 129580-63-8. Pack Sizes: 50 mg. Product ID: B0084-056858. Molecular formula: C10H24Cl2N2O4Pt. Mole weight: 500.28. Custom synthesis is available. Send your inquiries for more information.
London
Satraplatin
Satraplatin. CAS No. 129580-63-8. Product ID: C-22939.
CARBONE SCIENTIFIC UK
Sauchinone
Sauchinone, coming from the herbs of Saururus chinensis(Lour.) Baill, is a useful adjunctive treatment for bacterial infection. Sauchinone inhibited oxidative stress, as assessed by stainings of 4-hydroxynonenal and nitrotyrosine: these events may have a role in its inhibitory effects on HSCs activation. Sauchinone attenuated CCl4-induced liver fibrosis and TGF-β1-induced HSCs activation, which might be, at least in part, mediated by suppressing autophagy and oxidative stress in HSCs. Sauchinone protects skin keratinocytes through inhibition of extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 MAPK signaling via upregulation of oxidative defense enzymes. Uses: Anti-inflammatory/antibacterial. Group: Pharmaceutical. Alternative Names: (5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one; (5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one. CAS No. 177931-17-8. Pack Sizes: 10 mg. Product ID: B2703-464575. Molecular formula: C20H20O6. Mole weight: 356.36. Custom synthesis is available. Send your inquiries for more information.
London
Savinin
Savinin isolated from the heartwood of Pterocarpus santalinus. It exhibits potent spermicidal activity and significant insecticidal activity. Uses: Antifungal. Group: Pharmaceutical. Alternative Names: (4R)-4,5-Dihydro-4-(1,3-benzodioxole-5-ylmethyl)-3-[(E)-1,3-benzodioxol-5-ylmethylene]furan-2(3H)-one; (3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylidene)oxolan-2-one. CAS No. 493-95-8. Pack Sizes: 1 mg. Product ID: NP4076. Molecular formula: C20H16O6. Mole weight: 352.3. Custom synthesis is available. Send your inquiries for more information.
London
Savolitinib
Savolitinib is a tyrosine kinase inhibitor with potential anticancer activity. Group: Pharmaceutical. Alternative Names: Volitinib; HMPL 504; HMPL0-504; HMPL504; AZD 6094; AZD 6094; AZD-6094; Savolitinib. CAS No. 1313725-88-0. Pack Sizes: 50 mg. Product ID: B0084-462234. Molecular formula: C17H15N9. Mole weight: 345.37. Custom synthesis is available. Send your inquiries for more information.
London
Sawdust Raucher Gold Oak
Sawdust Raucher Gold Oak. At Tan International we supply a wide range of products covering all industry sectors
Scotland
SAW PALMETTO BERRY
SAW PALMETTO BERRY - Our signature range of liquid botanical extracts
England, Scotland
SAW PALMETTO SEED
SAW PALMETTO SEED - Our signature range of liquid botanical extracts
England, Scotland
Saxagliptin Cyclic Amide
An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type II diabetes. Group: Pharmaceutical. Alternative Names: Saxagliptin EP Impurity C. CAS No. 1350800-77-9. Pack Sizes: 2.5 mg. Product ID: B0016-479457. Molecular formula: C18H24N2O3. Mole weight: 316.4. Custom synthesis is available. Send your inquiries for more information.
London
Saxagliptin Cyclic Amidine Impurity
An impurity of saxagliptin. Saxagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type II diabetes. Group: Pharmaceutical. Alternative Names: Saxagliptin EP Impurity A; (1aS,4S,6aR,7aS)-6-Amino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-3H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one. CAS No. 1350800-76-8. Pack Sizes: 5 mg. Product ID: B0016-479455. Molecular formula: C18H25N3O2. Mole weight: 315.42. Custom synthesis is available. Send your inquiries for more information.
London
Saxagliptin Keto Impurity
An impurity of Saxagliptin. Saxagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP-4) used as a hypoglycemic drug. It was approved to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: (1S,3S,5S)-2-((R)-2-amino-2-((1s,3R,5S,7S)-4-oxoadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Pack Sizes: 2.5 mg. Product ID: B0016-007239. Molecular formula: C18H23N3O2. Mole weight: 313.4. Custom synthesis is available. Send your inquiries for more information.
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Saxagliptin monohydrate
Saxagliptin hydrate is a selective and reversible DPP4 inhibitor. It demonstrates greater specificity for DPP4 than for either the DPP8 or DPP9 enzymes. It reduces the degradation of the incretin hormone glucagon-like peptide-1, thereby enhancing its actions, and is associated with improved β-cell function and suppression of glucagon secretion. Group: Pharmaceutical. Alternative Names: BMS-477118 hydrate; BMS 477118 hydrate; BMS477118 hydrate; Onglyza hydrate. CAS No. 945667-22-1. Pack Sizes: 1 g. Product ID: B2692-452181. Molecular formula: C18H27N3O3. Mole weight: 333.43. Custom synthesis is available. Send your inquiries for more information.
London
SB1317
SB1317 is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. It dose-dependently inhibits signaling pathways downstream of CDKs, JAK2 and FLT3 in cancer cells with the main targets being CDKs. SB1317 is anti-proliferative in a broad range of tumor cell lines, inducing G1 cell cycle arrest and apoptosis. In vivo, SB1317 exhibits favorable pharmacokinetics after oral dosing in xenograft models and accumulates in tumor tissues, inducing an effective blockade of both CDK and STAT signaling. SB1317 induces tumor regression after oral dosing on both daily and intermittent schedules in a murine model of mutant-FLT3 leukemia (MV4-11) and prolongs survival in a disseminated AML model with wild-type FLT3 and JAK2 (HL-60). SB1317 is active in various models of leukemia and provide a rationale for the ongoing clinical evaluation of TG02 in patients with advanced leukemias. Group: Pharmaceutical. Alternative Names: TG02; TG 02; TG-02; SB1317 (Double bond E); TG02 (Double bond E). CAS No. 1204918-72-8. Pack Sizes: 20 mg. Product ID: B0084-457585. Molecular formula: C23H24N4O. Mole weight: 372.46. Custom synthesis is available. Send your inquiries for more information.
London
SB-203580
SB 203580 is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM, also blocks PKB phosphorylation with IC50 of 3-5 μM. Uses: Enzyme inhibitors. Group: Pharmaceutical. Alternative Names: SB203580; SB203580; SB 203580. CAS No. 152121-47-6. Pack Sizes: 1 g. Product ID: B2693-084679. Molecular formula: C21H16FN3OS. Mole weight: 377.437. Custom synthesis is available. Send your inquiries for more information.
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SB239063
SB239063 is a potent p38MAPK inhibitor. SB 239063 had an IC(50) of 44 nM for inhibition of recombinant purified human p38alpha. In lipopolysaccharide-stimulated human peripheral blood monocytes, SB 239063 inhibited interleukin-1 and tumor necrosis factor-alpha production. SB 239063 may be useful for the treatment of asthma and other inflammatory disorders. Uses: Protein kinase inhibitors. Group: Pharmaceutical. Alternative Names: SB-239063; SB 239063. CAS No. 193551-21-2. Pack Sizes: 100 mg. Product ID: B2693-196670. Molecular formula: C20H21FN4O2. Mole weight: 368.412. Custom synthesis is available. Send your inquiries for more information.
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SB 277011A dihydrochloride
SB 277011A dihydrochloride is a selective and brain penetrating dopamine D3 receptor antagonist (pKi = 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B, respectively) with 100-fold selectivity over the hD2 receptor and over 66 other receptors. Group: Pharmaceutical. Alternative Names: SB 277011A dihydrochloride; SB277011A dihydrochloride; SB-277011A dihydrochloride; N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide dihydrochloride. CAS No. 1226917-67-4. Pack Sizes: 50 mg. Product ID: B2693-320560. Molecular formula: C28H30N4O.2HCl. Mole weight: 511.49. Custom synthesis is available. Send your inquiries for more information.
London
SB-334867 hydrochloride
SB-334867 hydrochloride is the first non-peptide selective antagonist of orexin receptor subtype OX1 and shows in vivo activity following ip dosing. Group: Pharmaceutical. Alternative Names: SB-334867 HCl; Urea, N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-, hydrochloride (1:1); N-(2-methyl-6-benzoxazolyl)-N'-1,5-napthyridin-4-yl)urea monohydrochloride. CAS No. 249889-64-3. Pack Sizes: 100 mg. Product ID: B1370-103558. Molecular formula: C17H14ClN5O2. Mole weight: 355.78. Custom synthesis is available. Send your inquiries for more information.
London
SB-3CT
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. SB-3CT is a 2-[(arylsulfonyl)methyl]thiirane that achieves potent inhibition, by a thiirane-opening mechanism, of the MMP2 and MMP9 zinc metalloproteases. SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. Besides, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis. Group: Pharmaceutical. Alternative Names: MMP-2/MMP-9 Inhibitor IV; 2-((4-phenoxyphenylsulfonyl)methyl)thiirane; SB-3CT; SB3CT; SB3-CT; IN1250; IN 1250; IN-1250. CAS No. 292605-14-2. Pack Sizes: 20 mg. Product ID: B0084-369142. Molecular formula: C15H14O3S2. Mole weight: 306.394. Custom synthesis is available. Send your inquiries for more information.
London
SB431542
SB-431542 is a potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC50 = 94 nM). It is a less potent antagonist of ALK4 (IC50 = 140 nM) and ALK7. It does not affect the BMP receptors ALK2, ALK3, ALK6, or a panel of other kinases tested. Uses: Reprogramming, differentiation. Group: Pharmaceutical. Alternative Names: SB431542; SB-431542; SB 431542. CAS No. 301836-41-9. Pack Sizes: 50 mg. Product ID: B0084-211014. Molecular formula: C22H16N4O3. Mole weight: 384.39. Custom synthesis is available. Send your inquiries for more information.
London
SB525334
SB-525334 is a potent inhibitor of the TGF-β receptor 1 (TGF-β R1, ALK5) kinase (IC50 = 14.36 nM). It is ~4-fold less effective against ALK4 and inactive against ALK2, ALK3, and ALK6. Group: Pharmaceutical. Alternative Names: SB525334; SB-525334; SB 525334. CAS No. 356559-20-1. Pack Sizes: 50 mg. Product ID: B2693-263896. Molecular formula: C21H21N5. Mole weight: 343.42494. Custom synthesis is available. Send your inquiries for more information.
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SB705498
SB705498 is a TRPV1 antagonist for hTRPV1, antagonizes capsaicin, acid, and heat activation of TRPV1 with IC50 of 3 nM, 0.1 nM and 6 nM, shows a degree of voltage dependence, exhibits >100-fold selectivity for TRPV1 over TRPM8. Group: Pharmaceutical. Alternative Names: SB-705498; SB 705498; SB705498. CAS No. 501951-42-4. Pack Sizes: 25 mg. Product ID: B2693-453478. Molecular formula: C17H16BrF3N4O. Mole weight: 429.23. Custom synthesis is available. Send your inquiries for more information.
London
SB742457
SB742457 is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease. Group: Pharmaceutical. Alternative Names: SB742457; SB 742457; SB-742457; RVT-101; RVT 101; RVT101. intepirdine. GSK 742457; GSK742457; GSK-742457. CAS No. 607742-69-8. Pack Sizes: 50 mg. Product ID: B0084-404961. Molecular formula: C19H19N3O2S. Mole weight: 353.44. Custom synthesis is available. Send your inquiries for more information.
London
SBE-β-CD
SBE-β-CD, also called as Sulfobutylether beta-cyclodextrin sodium, is a β-Cyclodextrin derivative with sulfobutyl ether groups and sodium ions substituted designed to optimize the drug properties. β-Cyclodextrin is commonly used to produce HPLC columns allowing chiral enantiomers separation. Group: Pharmaceutical. Alternative Names: SBE4-b-CyD; SBECD; Betadex Sulfobutyl Ether Sodium; Sulfobutyl Ether Beta-Cyclodextrin; Sulfobutyl Ether-Beta-Cyclodextrin; Sodium Sulphobutylether-Beta-Cyclodextrin. CAS No. 182410-00-0. Pack Sizes: 25 g. Product ID: B1999-002792. Custom synthesis is available. Send your inquiries for more information.
London
SBS Block Copolymer
Rubber. Adhesive raw materials
England, Surrey
SC 26196
SC 26196 is a selective Δ6 desaturase inhibitor (IC50 = 0.2 μM in vitro) that displays >100 fold selectivity over Δ5 and Δ9 desaturases (IC50 >200 μM in vitro). SC 26196 completely inhibits the conversion of linoleic acid to arachidonic acid (AA). It exhibits anti-inflammatory properties in a mouse edema model. Group: Pharmaceutical. Alternative Names: α,α-Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile; PF-o6341724; FT 0674530; SC 26196; FT0674530; SC26196; FT-0674530; SC-26196. CAS No. 218136-59-5. Pack Sizes: 100 mg. Product ID: B2693-129639. Molecular formula: C27H29N5. Mole weight: 423.55. Custom synthesis is available. Send your inquiries for more information.
London
SC40230
SC40230 is a new anti-arrhythmic agent, which is different in structure from other known anti-arrhythmic drugs. Group: Pharmaceutical. Alternative Names: 2-[2-[acetyl(propan-2-yl)amino]ethyl]-2-(2-chlorophenyl)-4-piperidin-1-ylbutanamide; alpha-(2-(acetyl(1-methylethyl)amino)ethyl)-alpha-(2-chlorophenyl)-1-piperidinebutanamide; bidisomide; bidisomide, (+)-isomer; bidisomide, (+-)-isomer; bidisomide, (-)-isomer; SC 40230; SC-40230. CAS No. 116078-65-0. Pack Sizes: 1mg;1g;10g. Product ID: 116078-65-0. Molecular formula: C22H34ClN3O2. Mole weight: 407.98. Custom synthesis is available. Send your inquiries for more information.
London
SC75741
SC75741 is a potent NF-κB inhibitor (EC50=200 nM). Group: Pharmaceutical. Alternative Names: SC 75741; SC-75741; 4-Thiazolecarboxamide, N-(6-benzoyl-1H-benzimidazol-2-yl)-2-(1-thieno[3,2-d]pyrimidin-4-yl-4-piperidinyl)-. CAS No. 913822-46-5. Pack Sizes: 100 mg. Product ID: B1370-102306. Molecular formula: C29H23N7O2S2. Mole weight: 565.67. Custom synthesis is available. Send your inquiries for more information.
London
Scabioside C
Scabioside C is extracted from Pulsatilla chinensis (Bunge) Regel. Uses: Topoisomerase i inhibitors. Group: Pharmaceutical. Alternative Names: Scabioside C; 17233-22-6; (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; Leontoside B; CHEMBL466974; AKOS040760693; HY-107309; CS-0027942. CAS No. 17233-22-6. Pack Sizes: 5 mg. Product ID: B0005-465777. Molecular formula: C41H66O13. Mole weight: 767. Custom synthesis is available. Send your inquiries for more information.
London
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