A directory of where to buy chemicals in the UK including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
A semi-synthetic product produced by hydrolysing the disaccharide unit of ivermectin. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The aglycone is used as a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Group: Pharmaceutical. Alternative Names: Dihydroavermectin B1 aglycone; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; 22,23-Dihydroavermectin B1a Aglycon; Ivermectin Aglycone; 13-O-De[4-O-(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl]-22,23-dihydro-27-noravermectin A1. CAS No. 123997-59-1. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04574. Molecular formula: C34H50O8. Mole weight: 586.76. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin B1b
Ivermectin B1b is a minor component of Ivermectin, a semi-synthetic derivative of Abamectin. Ivermectin is a medication that is effective against many types of parasites. Group: Pharmaceutical. Alternative Names: Ivermectin B1b;Avermectin H2B1b;Ivermectin Component B1b;dihydroavermectin B1b;70209-81-3;22,23-dihydroavermectin B1b;0W28CYI3TU;CHEBI:63943;Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-;(1R,4S,5'S,6R,6'R,8R,10E,12S,13S,14E,16E,20R,21R,24S)-21,24-dihydroxy-12-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one;UNII-0W28CYI3TU;Stromectol (TN);Soolantra (TN);EINECS 274-384-5;Sklice (TN);H2B1b;CHEMBL552;Ivermectin (JAN/USP/INN);SCHEMBL313003;DTXSID3023182;VARHUCVRRNANBD-PVVXTEPVSA-N;IVERMECTIN COMPONENT B1B [MI];HY-125729;CS-0093431;NS00093438;D00804;Q27132925;5-O-DEMETHYL-25-DE(1-METHYLPROPYL)-22,23-DIHYDRO-25-(1-METHYLETHYL)AVERMECTIN A1A;Avermectin A(sub 1a), 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-. CAS No. 70209-81-3. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03934. Molecular formula: C20H38N6O4. Mole weight: 426.6. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin-d2
An isotope labelled Ivermectin. Ivermectin is a medication used to treat certain parasitic roundworm infections. Group: Pharmaceutical. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2. Pack Sizes: 1mg;1g;10g. Molecular formula: C48H72O14D2. Mole weight: 877.13. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin-[d2]
Ivermectin-[d2] is the labelled analogue of Ivermectin, which is a semi-synthetic derivative of Abamectin consisting of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An in vitro inhibitor of SARS-CoV-2/Covid-19. Group: Pharmaceutical. Alternative Names: 22,23-Dihydroavermectin B1-d2; 22,23-Dihydro C-076B1-d2; Heartgard 30; Ivomec-d2; Ivosint-d2; Mectizan-d2; Stromectol-d2; Uvemec-d2; Vermic-d2; Zimecterin-d2. Pack Sizes: 1mg;1g;10g. Product ID: BLP-005810. Molecular formula: C48H72D2O14. Mole weight: 877.11. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin EP Impurity D
Ivermectin EP Impurity D is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Pharmaceutical. Alternative Names: 5-O-demethyl-28-oxo-22,23-dihydroavermectin A1a; 28-oxoH2B1a; 28-Oxo Ivermectin B1a (Impurity); 5-O-Demethyl-22,23-dihydro-28-oxo-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. CAS No. 102190-55-6. Pack Sizes: 1mg;1g;10g. Product ID: 102190-55-6. Molecular formula: C48H72O15. Mole weight: 889.1. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin EP Impurity E
Ivermectin EP Impurity E is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Pharmaceutical. Alternative Names: 5-O,12-didemethyl-12-ethyl-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1a. Pack Sizes: 1mg;1g;10g. Molecular formula: C49H76O14. Mole weight: 889.13. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin EP Impurity F
Ivermectin EP Impurity F is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Pharmaceutical. Alternative Names: 5-O,12-didemethyl-25-de(1-methylpropyl)-12-ethyl-25-(1-methylethyl)-22,23-dihydroavermectin A1a; 12-demethyl-12-ethyl-H2B1b. Pack Sizes: 1mg;1g;10g. Molecular formula: C48H74O14. Mole weight: 875.11. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin EP Impurity G
Ivermectin EP Impurity G is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Pharmaceutical. Alternative Names: Ivermectin B1 Aglycon; (6R,13S,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-[(1S)-1-methylpropyl]-milbemycin B; [6R,13S,25R(S)]-5-O-Demethyl-28-deoxy-6,28-epoxy-13-hydroxy-25-(1-methylpropyl)-milbemycin B; H2B1a aglycone. CAS No. 73162-95-5. Pack Sizes: 1mg;1g;10g. Product ID: 73162-95-5. Molecular formula: C34H50O8. Mole weight: 586.77. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin EP Impurity H
Ivermectin EP Impurity H is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Pharmaceutical. Alternative Names: Ivermectin B1 Mono-sugar Derivative; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. CAS No. 71837-27-9. Pack Sizes: 1mg;1g;10g. Product ID: 71837-27-9. Molecular formula: C41H62O11. Mole weight: 730.94. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin EP Impurity J
Ivermectin EP Impurity J is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Pharmaceutical. Alternative Names: 2,3-didehydro-5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-3,4,22,23-tetrahydroavermectin A1a; Δ2,3H2B1b. Pack Sizes: 1mg;1g;10g. Molecular formula: C47H72O14. Mole weight: 861.08. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin EP Impurity K
Ivermectin EP Impurity K is an impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Pharmaceutical. Alternative Names: 3,4-Dihydro Ivermectin (Mixture of Diastereomers) ; 5-O-Demethyl-3,4,22,23-tetrahydro-avermectin A1a; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Avermectin A1a Deriv. CAS No. 74567-01-4. Pack Sizes: 1mg;1g;10g. Product ID: 74567-01-4. Molecular formula: C48H76O14. Mole weight: 877.13. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin monosaccharide
A semi-synthetic product produced by selective hydrolysis of the terminal saccharide unit. It is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. It is a sensitive probe for the detection of some types of ivermectin resistance. An impurity of Ivermectin. Group: Pharmaceutical. Alternative Names: Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethyl-22,23-dihydro-avermectin A1a; 4'-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)ivermectin B1. CAS No. 123997-64-8. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04575. Molecular formula: C41H62O11. Mole weight: 730.92. Custom synthesis is available. Send your inquiries for more information.
Ivermectin Photolytic degradation impurity-2 (aldehyde impurity) is a degradation impurity of Ivermectin, an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. Group: Pharmaceutical. Alternative Names: (2R,2a'Z,4'E,5S,6R,6'S,7'S,8'E,11'R, 15'S, 17a'R,20'R,20a'S)-6-((S)-sec-butyl)-20'-hydroxy-7'-(((2R,4S,5S,6S)-5-(((2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,6',8',19'-tetramethyl-17'-oxo-2a1',3,4,5,6,6',10',11',14',15',17',17a',20',20a'-tetra decahydro-2'H,7'H-spir[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-2'-carbaldehyde. Pack Sizes: 1mg;1g;10g. Custom synthesis is available. Send your inquiries for more information.
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Ivermectin suppliers wanted
Ivermectin suppliers required with local stock available in the UK
Ivosidenib is an oral inhibitor that specifically inhibits a mutated form of IDH1 in the cytoplasm, which blocks the proliferation of tumor cells expressing IDH1. Group: Pharmaceutical. Alternative Names: AG-120; AG 120; AG120; (2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide; Glycinamide, N2-[1-(4-cyano-2-pyridinyl)-5-oxo-L-prolyl]-2-(2-chlorophenyl)-N1-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)-, (2S)-; TIBSOVO; (S)-N-((S)-1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide. CAS No. 1448347-49-6. Pack Sizes: 100 mg. Product ID: B0084-474585. Molecular formula: C28H22ClF3N6O3. Mole weight: 582.96. Custom synthesis is available. Send your inquiries for more information.
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IVY
IVY - Our signature range of liquid botanical extracts
England, Scotland
IWR-1-endo
IWR-1-endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 value of 180 nM. Group: Pharmaceutical. Alternative Names: IWR-1; IWR 1; IWR1; IWR-1-endo. CAS No. 1127442-82-3. Pack Sizes: 25 mg. Product ID: B0084-262341. Molecular formula: C25H19N3O3. Mole weight: 409.44. Custom synthesis is available. Send your inquiries for more information.
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IXA4
IXA4 is a highly selective and non-toxic IRE1/XBP1s activator, which activates the IRE1/XBP1s signaling, regardless of the global activation of the unfolded protein response (UPR) or other stress-responsive signaling pathways, such as heat shock response or oxidative stress response. IXA4 reduces APP secretion by activating IRE1. IXA4 therapy improves systemic glucose metabolism and hepatic insulin action through IRE1-dependent liver transcriptomic remodeling, thereby reducing glucose production and steatosis. IXA4-stimulated IRE1 activation also enhances pancreatic function. Group: Pharmaceutical. Alternative Names: N-(1-(2-(methyl(2-(p-tolyloxy)ethyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)-3-phenoxypropanamide; 1H-Pyrazole-1-acetamide, N-methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]-. CAS No. 1185329-96-7. Pack Sizes: 100 mg. Product ID: B1370-382267. Molecular formula: C24H28N4O4. Mole weight: 436.5. Custom synthesis is available. Send your inquiries for more information.
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Ixabepilone
Ixabepilone (also known as azaepothilone B, or BMS-247550) is an orally bioavailable microtubule inhibitor. Ixabepilone was a semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. Ixabepilone was approved in 2007. Group: Pharmaceutical. Alternative Names: Azaepothilone B; BMS247550; BMS-247550; BMS 247550; Ixempra. CAS No. 219989-84-1. Pack Sizes: 5 mg. Product ID: B0084-063099. Molecular formula: C27H42N2O5S. Mole weight: 506.7. Custom synthesis is available. Send your inquiries for more information.
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Ixazomib Citrate
The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM. Group: Pharmaceutical. Alternative Names: 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; MLN9708; MLN-9708; MLN 9708. CAS No. 1239908-20-3. Pack Sizes: 100 mg. Product ID: BBF-04173. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. Custom synthesis is available. Send your inquiries for more information.