A directory of where to buy chemicals in the UK including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
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| Product | Description | |
|---|---|---|
| Ganoderol B | Ganoderol B also called ganodermadiol is a natural triterpenoid found in the fruiting body of Ganoderma lucidum, it is an angiotensin-converting enzyme inhibitor and is a potent α-glucosidase inhibitor isolated from the fruiting body of Ganoderma lucidum. Ganoderol B exhibits the activity of anti-androgen. Uses: Anti-androgen. Group: Pharmaceutical. CAS No. 104700-96-1. Pack Sizes: 5 mg. Product ID: NP6278. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Ganolactone B | Ganolactone B is a lanostane triterpenoid isolated from the fruit body of Ganoderma lucidum. Group: Pharmaceutical. CAS No. 1028449-53-7. Pack Sizes: 5 mg. Product ID: B0005-053658. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GANT-61 | GANT 61 is a GLI antagonist that inhibits GLI1 activation of gene expression with an IC50 value of 5 μM. Group: Pharmaceutical. CAS No. 500579-04-4. Pack Sizes: 100 mg. Product ID: B0084-272119. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gap 26 | Gap 26 is a gap junction blocker which is corresponding to residues 63 - 75 of connexin 43. Gap 26 was shown to attenuate rhythmic contractile activity of rabbit arterial smooth muscle (IC50 = 28.4 μM). It also inhibits IP3-induced ATP release but does not inhibit gap junctional coupling in endothelial cells. Group: Pharmaceutical. CAS No. 197250-15-0. Pack Sizes: 10 mg. Product ID: BAT-006105. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gap 27 | Gap 27, a peptide derived from connexin 43, is a gap junction inhibitor. Group: Pharmaceutical. CAS No. 198284-64-9. Pack Sizes: 10 mg. Product ID: BAT-006215. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Garbanzol | Garbanzol, a revolutionary therapeutic agent with mighty anti-inflammatory properties, proffers a potential cure for a myriad of inflammatory ailments. Counted among them are rheumatoid arthritis, psoriasis, and inflammatory bowel disease. By constraining vital enzymes linked with inflammation, Garbanzol governs the synthesis of pro-inflammatory cytokines. Encouragingly, clinical trials demonstrate an encouraging safety profile, and an exceptional tolerance capacity. Group: Pharmaceutical. CAS No. 1226-22-8. Pack Sizes: 1 mg. Product ID: NP2448. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Garcinone C | Garcinone C is isolated from the fruits of Garcinia mangostana. It is the most potent inhibitor of AChE, and it exhibits either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNEhuman cancer cell lines. Group: Pharmaceutical. CAS No. 76996-27-5. Pack Sizes: 20 mg. Product ID: NP7246. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Garcinone D | Garcinone D usually comes from the fruits of Garcinia mangostana. It inhibited p65 activation with IC50 values of 3.2 microg/ml. Group: Pharmaceutical. CAS No. 107390-08-9. Pack Sizes: 25 mg. Product ID: B1370-437812. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GARDEN ANGELICA | GARDEN ANGELICA - Our signature range of liquid botanical extracts |  England, Scotland |
| Gardenin B | Gardenin B is a natural flavonoid compound found in several plants. Group: Pharmaceutical. CAS No. 2798-20-1. Pack Sizes: 5 mg. Product ID: NP1961. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gardenoside | Gardenoside is an iridoid compound found in the fruits of Gardenia jasminoides Ellis. Gardenoside exhibits anti-inflammatory, laxative, cholagogic and analgesic activities. It was shown to be effective toward HCl/ethanol induced gastric injury in mice and prevents cellular steatosis. Group: Pharmaceutical. CAS No. 24512-62-7. Pack Sizes: 5 mg. Product ID: NP3735. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GARDEN PEA | GARDEN PEA - Our signature range of liquid botanical extracts | England, Scotland |
| GARDEN STRAWBERRY SEED | Product Name: GARDEN STRAWBERRY SEED. Form: Whole. INCI Monograph: FRAGARIA ANANASSA (STRAWBERRY) SEED (proposed). Ingredient Source: Plant. Pink/tan seeds. Natural Exfoliants | England, Scotland |
| Gardiquimod | Gardiquimod is a small-molecule agonist of TLR7. It induces the activation of NF-κB in HEK 293 cells expressing TLR7. Uses: Toll-like receptor agonists. Group: Pharmaceutical. CAS No. 1020412-43-4. Pack Sizes: 100 mg. Product ID: B2693-473891. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gardneramine | Gardneramine is an indole alkaloid isolated from the roots of Gardneria multiflora Makino, which displays a local anesthetic effect. Group: Pharmaceutical. CAS No. 34274-91-4. Pack Sizes: 1 mg. Product ID: NP0301. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gardoside | Gardoside is found in the fruits of Gardenia jasminoides. Group: Pharmaceutical. CAS No. 54835-76-6. Pack Sizes: 10 mg. Product ID: B2703-334872. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GARLIC | GARLIC - Our signature range of liquid botanical extracts | England, Scotland |
| Garlic and Herb Mix | Garlic and Herb Mix. At Tan International we supply a wide range of products covering all industry sectors |  Scotland |
| Garlic Powder Food Grade | Garlic Powder Food Grade. At Tan International we supply a wide range of products covering all industry sectors | Scotland |
| Gartanin | Gartanin is isolated from the stem bark of Garcinia mangostana. It could be a multiple targeting agent into its chemopreventive properties for human urinary bladder cancer. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells. Uses: Antifungal property; antioxidant, anti - inflammatory properties; antineoplastic property. Group: Pharmaceutical. CAS No. 33390-42-0. Pack Sizes: 10 mg. Product ID: NP7262. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GAS JAR LID | GAS JAR LID, UK suppliers of laboratory chemicals and apparatus needed |  |
| GAS JARS | GAS JARS, UK suppliers of laboratory chemicals and apparatus needed | |
| GAS LIGHTER, PIEZO | GAS LIGHTER, PIEZO, Suppliers of UK laboratory chemicals wanted | |
| Gastrin I (human) | Gastrin I (human) is an endogenous peptide produced by stomach and it acts as a selective CCK2 receptor agonist. Gastrin I stimulates gastric acid secretion in vivo, and increases levels of cytosolic calcium in isolated rabbit stomach parietal cells (EC50 = 11 nM). Group: Pharmaceutical. CAS No. 10047-33-3. Pack Sizes: 2.5 mg. Product ID: BAT-006092. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gastrodin Impurities | Gastrodin Impurities are paramount in biomedical explorations, facilitating a detailed analysis of gastrodin's pharmacokinetic profile, crucial for addressing neurological maladies such as Alzheimer's and Parkinson's. Scrutiny of these impurities is pivotal for enhancing gastrodin's therapeutic efficacy and safety, thereby advancing neuroprotective treatment methodologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GAS WASH BOTTLE | GAS WASH BOTTLE, Suppliers of UK laboratory chemicals wanted | |
| Gatifloxacin | 1g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H22FN3O4. CAS No. 112811-59-3. Prepack ID : 32445577-1g. Molecular Weight : 375.4. |  |
| Gatifloxacin Impurities | Gatifloxacin Impurities are critical in the quality assessment and development of pharmaceuticals for managing bacterial infections. They provide essential insights into the stability, efficacy, and safety profile of Gatifloxacin, an antibiotic used against pathogens causing respiratory tract infections, urinary tract infections, and conjunctivitis. Understanding these impurities aids in optimizing therapeutic formulations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gatifloxacin sesquihydrate | 5g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H22FN3O4 ·1.5H2O. CAS No. 180200-66-2. Prepack ID : 89983539-5g. Molecular Weight : 402.42. | |
| GAUZE 125mm | GAUZE 125mm, Suppliers of laboratory chemicals wanted in the United Kingdom | |
| GAUZE 125x125mm CERAMIC | GAUZE 125x125mm CERAMIC, UK suppliers of laboratory chemicals and apparatus needed | |
| GAUZE 150mm | GAUZE 150mm, UK suppliers of laboratory chemicals wanted | |
| GAUZE 150x150mm CERAMIC | GAUZE 150x150mm CERAMIC, Suppliers of UK laboratory chemicals wanted | |
| GBT-440 | GBT-440 is a substituted benzaldehyde compound that can modulate sickle hemoglobin (HbS) for treatment of disorders. Uses: Hematologic agents. Group: Pharmaceutical. CAS No. 1446321-46-5. Pack Sizes: 100 mg. Product ID: B0084-474581. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GC376 sodium | GC376 is a 3CLpro inhibitor which is previously reported to be active against the 3CLpro of multiple coronaviruses, including SARS-CoV, but with highest potency against FIPV in cell culture. GC376 inhibits the replication of viruses TGEV, FIPV and PTV with IC50 values of 0.15, 0.2 and 0.15 μM. Group: Pharmaceutical. CAS No. 1416992-39-6. Pack Sizes: 50 mg. Product ID: B0084-007378. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDC-0077 | GDC-0077 is an orally available and selective PI3K inhibitor (IC50 = 0.038 + 0.003 nM) with > 300-fold selective over other Class I PI3K isoforms. GDC-0077 exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Group: Pharmaceutical. CAS No. 2060571-02-8. Pack Sizes: 100 mg. Product ID: B2693-007357. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDC-0084 | GDC-0084, a PI3K inhibitor, has been found to have probable antineoplastic effect and could pass blood-brain barrier with favourable penetration. It was just licensed to Novogen and start a Phase II trial for Glioma. Uses: Gdc-0084 is a pi3k inhibitor that has been found to have probable antineoplastic effect and could pass blood-brain barrier with favourable penetration. Group: Pharmaceutical. CAS No. 1382979-44-3. Pack Sizes: 300 mg. Product ID: B0084-474534. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDC-0152 | GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity. Smac mimetic GDC-0152 binds to the Smac binding groove on IAPs, including the direct caspase inhibitor X chromosome-linked IAP (XIAP) and the cellular IAPs 1 and 2, which may inhibit their activities and promote the induction of apoptosis through apoptotic signaling pathways. IAPs are overexpressed by many cancer cell types and suppress apoptosis by binding to and inhibiting active caspases-3, -7 and -9 via their baculoviral lAP repeat (BIR) domains. Smac, the endogenous IAP antagonist, relies on its N-terminal four amino-acid motif for binding to IAPs. Group: Pharmaceutical. CAS No. 873652-48-3. Pack Sizes: 50 mg. Product ID: B2693-462525. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDC-0853 | GDC-0853 is a Bruton's tyrosine kinase (BTK) inhibitor originated by Genentech. GDC-0853 can inhibit the activity of BTK and prevent the activation of the B-cell antigen receptor (BCR) signaling pathway. This leads to the inhibition of the growth of malignant B-cells that overexpress BTK. Phase III clinical trials for the treatment of Multiple sclerosis and Phase II clinical trials for the treatment of Chronic urticaria and Systemic lupus erythematosus are on-going. Uses: Rheumatoid arthritis; autoimmune disorders. Group: Pharmaceutical. CAS No. 1434048-34-6. Pack Sizes: 100 mg. Product ID: B2693-475436. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDC0941 | GDC-0941 is a potent pan inhibitor of class I catalytic subunits of PI3K that inhibits p110α, β, δ, and γ with IC50 values of 3, 33, 3, and 75 nM. Group: Pharmaceutical. CAS No. 957054-30-7. Pack Sizes: 50 mg. Product ID: B0084-101126. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDC-0994 | GDC-0994, also known as RG7842, is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0994 inhibits both ERK phosphorylation and activation of ERK-mediated signal transduction pathways. This prevents ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 1453848-26-4. Pack Sizes: 50 mg. Product ID: B2693-462528. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDP-D-glucose disodium salt | GDP-D-glucose sodium salt, a biochemical component for metabolic pathway study and intracellular signaling, plays an imperative role in glucose metabolism. Its potential therapeutic agent property for various diseases is highlighted in recent diabetes and cancer research. And its acknowledged proficiency in regulating the cell differentiation and proliferation further consolidates its prominence. Group: Pharmaceutical. CAS No. 103301-72-0. Pack Sizes: 10 mg. Product ID: B1370-358024. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDP-D-mannose disodium salt | GDP-D-mannose disodium salt is an invaluable compound, playing a pivotal role in the research of disorders pertaining to compromised glucose metabolism. Functioning as a critical intermediate within biosynthetic pathways, it specifically facilitates the synthesis of sugar nucleotides. Group: Pharmaceutical. CAS No. 103301-73-1. Pack Sizes: 50 mg. Product ID: B2705-358025. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDP-L-fucose disodium salt | Substrate for fucosyltransferase. Group: Pharmaceutical. CAS No. 148296-47-3. Pack Sizes: 5 mg. Product ID: B2706-339907. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Geclosporin | Geclosporin is an impurity of cycloporine, which is an immunosuppressant used in the treatment of rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, etc. Uses: Immunosuppressant. Group: Pharmaceutical. CAS No. 74436-00-3. Pack Sizes: 5 mg. Product ID: BBF-05767. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gedunin | Gedunin is a naturally occurring Hsp90 inhibitor. Induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). It also exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1 μM in parasite development and [3H]-hypoxanthine uptake assays respectively). Group: Pharmaceutical. CAS No. 2753-30-2. Pack Sizes: 2 mg. Product ID: B0084-272120. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gefapixant | Gefapixant is a P2X3 receptor (P2X3R) antagonist with IC50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. It is under a clinical trial for the treatment of chronic cough. Group: Pharmaceutical. CAS No. 1015787-98-0. Pack Sizes: 100 mg. Product ID: B2693-138428. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gefitinib | 100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C22H24ClFN4O3. CAS No. 184475-35-2. Prepack ID : 57220562-100mg. Molecular Weight : 446.9. | |
| Gefitinib | Gefitinib is an antineoplastic drug. Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both the high and low EGFR-expressing cell lines including NR6, NR6M and NR6W cell lines. The phosphorylation sites Tyr1173 and Tyr992 are less sensitive requiring higher concentrations of Gefitinib for inhibition. Group: Pharmaceutical. CAS No. 184475-35-2. Pack Sizes: 5 g. Product ID: BBF-04570. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gefitinib-[d6] | One of the isotopic labelled form of Gefitinib, which could be used as an antineoplastic agent. Group: Pharmaceutical. CAS No. 1228664-49-0. Pack Sizes: 10 mg. Product ID: BLP-014883. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gefitinib Impurities | Gefitinib Impurities are critical in the pharmaceutical evaluation and refinement of gefitinib, a tyrosine kinase inhibitor used to treat non-small cell lung cancer. These impurities facilitate robust quality control assessments and ensure therapeutic efficacy and safety in anti-cancer formulations, contributing to the advancement of precision oncology treatments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gefitinib Impurity II | Gefitinib Impurity II. Group: Pharmaceutical. CAS No. 153437-78-6. Pack Sizes: 10 mg. Product ID: B2694-471994. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Geissoschizine methyl ether | Geissoschizine methyl ether is an indole alkaloid isolated from Uncariae hooks. Geissoschizine methyl ether acts as a 5-HT7 receptor antagonist and also a potent acetylcholinesterase (AChE) inhibitor. Group: Pharmaceutical. CAS No. 60314-89-8. Pack Sizes: 5 mg. Product ID: NP0821. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gelatine | Gelatine. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 9000-70-8. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| GELATINE POWDER UN | GELATINE POWDER UN, Suppliers of laboratory chemicals wanted | |
| Gelatin powdered, from porcine skin | 100g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C31H27NO4. CAS No. 9000-70-8. Prepack ID : 20930194-100g. Molecular Weight : 477.55. | |
| Gelatin powdered, pure, from bovine skin, Ph.Eur,USP | 100g Pack Size. Group: Amino Acids, Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C31H27NO4. CAS No. 9000-70-8. Prepack ID : 90005605-100g. Molecular Weight : 477.55. | |
| Geldanamycin | 10mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C29H40N2O9. CAS No. 30562-34-6. Prepack ID : 48834712-10mg. Molecular Weight : 560.64. | |
| Geldanamycin | Geldanamycin is a benzoquinone ansamycin antibiotic that inhibits heat shock protein 90 (HSP90). Geldanamycin has been shown to promote survival of neural stem cells from oxidative stress via inhibition of HSP90. It displays potent antineoplastic properties and inhibits myeloma cell growth. Uses: Antibiotics, antineoplastic. Group: Pharmaceutical. CAS No. 30562-34-6. Pack Sizes: 200 mg. Product ID: BBF-01865. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gelomulide A | Gelomulide A is isolated from Suregada. Group: Pharmaceutical. CAS No. 122537-59-1. Pack Sizes: 1 mg. Product ID: NP1692. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gelomulide B | Gelomulide B is a diterpenoid found in Suregada multiflora. Group: Pharmaceutical. CAS No. 122537-60-4. Pack Sizes: 1 mg. Product ID: NP1694. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gelomulide N | Gelomulide N also called 1alpha,3beta-Diacetoxy-8beta,14beta-epoxy-ent-abiet-13(15)-en-16,12-olide, is a natural diterpenoid compound. Group: Pharmaceutical. CAS No. 1005212-02-1. Pack Sizes: 5 mg. Product ID: NP1220. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GEL PIGS | GEL PIGS Alchemy Gel Pigs are specially formulated solid gels systems used in oil pipeline applications to pig out lines and create temporary barriers. Category: Oilfield Chemicals | Alchemy Oilfield Services Scotland, Aberdeen |
| Gelsevirine | Gelsevirine, isolated from the herbs of Gelsemium elegans, could be developed as the treatment of anxiety-related disorders in human patients. Their anxiolytic mechanism may be involved in the agonist action of glycine receptor in the brain. Uses: Anxiolytic. Group: Pharmaceutical. CAS No. 38990-03-3. Pack Sizes: 1 mg. Product ID: NP0337. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gemcabene | Gemcabene is an orally available lipid-lowering small molecule designed to target known lipid metabolic pathways, as an adjunctive therapy to reduce LDL-C, hsCRP and triglycerides (TGs). Currentl, Gemcabene is under Phase-II clinical trials in Hypertriglyceridaemia in USA. Group: Pharmaceutical. CAS No. 183293-82-5. Pack Sizes: 100 mg. Product ID: B0084-244917. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gemcitabine | Gemcitabine is a nucleoside analogue used in chemotherapy. It treats cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer and bladder cancer. Group: Pharmaceutical. CAS No. 95058-81-4. Pack Sizes: 25 g. Product ID: NP3544. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gemcitabine (alpha-Isomer) Hydrochloride | Gemcitabine (alpha-Isomer) Hydrochloride is an α-Anomer of Gemcitabine. Gemcitabine is a nucleoside analogue used in chemotherapy. It treats cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer and bladder cancer. Group: Pharmaceutical. CAS No. 122111-05-1. Pack Sizes: 25 mg. Product ID: B2694-261177. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gemcitabine elaidate | Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Group: Pharmaceutical. CAS No. 210829-30-4. Pack Sizes: 25 mg. Product ID: B2706-225221. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gemcitabine hydrochloride | 5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H11F2N3O4 · HCl. CAS No. 122111-03-9. Prepack ID : 56199790-5g. Molecular Weight : 299.66. | |
| Gemcitabine hydrochloride | Gemcitabine induced NF-κB activity in BxPC-3, PANC-1, and MIA PaCa-2 cells and decreased the level of the NF-κB inhibitor IκBα in BxPC-3 and PANC-1 cells. Uses: Antimetabolites, antineoplastic. Group: Pharmaceutical. CAS No. 122111-03-9. Pack Sizes: 5 g. Product ID: B0046-464018. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
