A directory of where to buy chemicals in the UK including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
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| Product | Description | |
|---|---|---|
| Exatecan Mesylate | Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting the religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogs. Group: Pharmaceutical. CAS No. 169869-90-3. Pack Sizes: 500 mg. Product ID: BBF-04655. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Excisanin A | Excisanin A is a natural diterpenoid compound found in several plants. Group: Pharmaceutical. CAS No. 78536-37-5. Pack Sizes: 5 mg. Product ID: NP1445. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Excisanin B | Excisanin B is extracted from the herbs of Isodon japonicus. It inhibits production of nitric oxide in LPS-induced murine macrophage RAW264.7 cells. Group: Pharmaceutical. CAS No. 78536-36-4. Pack Sizes: 5 mg. Product ID: NP1397. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Exemestane Impurities | Exemestane Impurities are crucial in the biomedical field for quality control during the synthesis of exemestane, an aromatase inhibitor. Exemestane is primarily used in the treatment of estrogen-receptor-positive breast cancer in postmenopausal women, highlighting the essential role of these impurities in ensuring drug purity and therapeutic efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Exenatide acetate | Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Group: Pharmaceutical. CAS No. 914454-01-6. Pack Sizes: 100 mg. Product ID: BAT-010771. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Exendin 3 (9-39) | Exendin (9-39) is a specific and competitive glucagon-like peptide-1receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Exendin (9-39) inhibits insulin release and cAMP production caused by GLP-1 (7-36), exendin-3, and exendin-4. Group: Pharmaceutical. CAS No. 133514-43-9. Pack Sizes: 1 mg. Product ID: BAT-006203. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Exherin | Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N-cadherin, a cell- surface transmembrane glycoprotein of the cadherin superfamily of proteins involved in calcium-mediated cell-cell adhesion and signaling mechanisms; may be upregulated in some aggressive tumors and the endothelial cells and pericytes of some tumor blood vessels. Group: Pharmaceutical. CAS No. 229971-81-7. Pack Sizes: 10 mg. Product ID: BAT-010745. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Exosomes | Exosomes are small natural membrane vesicles released by a wide variety of cell types into the extracellular compartment by exocytosis. Exosomes are the smallest EVs and are of particular interest in the tumor microenvironment (TME), where they have been shown to directly mediate angiogenesis, tumor metastasis, and immunosuppression. Group: Pharmaceutical. Pack Sizes: 10 ml. Product ID: B1370-087452. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Exo-Tetrahydrodicyclopentadiene | Exo-Tetrahydrodicyclopentadiene (CAS# 2825-82-3 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 2825-82-3. Pack Sizes: 25 g. Product ID: B2699-178550. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Exoticin | Exoticin isolated from the herbs of Murraya exotica. Group: Pharmaceutical. CAS No. 13364-94-8. Pack Sizes: 1 mg. Product ID: NP2121. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| EXPANSION ADAPTER SOCKET | EXPANSION ADAPTER SOCKET, Suppliers of laboratory chemicals wanted |  |
| EXPANSION ADAPTOR SOCKET | EXPANSION ADAPTOR SOCKET, UK suppliers of laboratory chemicals wanted | |
| EXTRACTION THIMBLES | EXTRACTION THIMBLES, UK suppliers of laboratory chemicals wanted | |
| Exxsol D100 | Exxsol D100. At Tan International we supply a wide range of products covering all industry sectors |  Scotland |
| EYEBRIGHT | EYEBRIGHT - Our signature range of liquid botanical extracts |  England, Scotland |
| Eyeliss | Eyeliss is a cosmetic indegredient that has been used to relieve puffiness under eye bags and reduce dark circles beneath the eyes. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: BAT-006233. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| EYESHIELD, JUNIOR | EYESHIELD, JUNIOR, Suppliers of laboratory chemicals wanted | |
| Ezatiostat | Ezatiostat is a glutathione analog that acts as an inhibitor of glutathione S-transferase (GST) P1-1. TLK117, the active form of ezatiostat, inhibits GSTP1-1, resulting in phosphorylation of JNK, restoring JNK-mediated cellular proliferation and differentiation signaling pathways. Group: Pharmaceutical. CAS No. 168682-53-9. Pack Sizes: 25 mg. Product ID: BAT-010079. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C24H21F2NO3. CAS No. 163222-33-1. Prepack ID : 74798364-1g. Molecular Weight : 409.4. |  |
| Ezetimibe | Ezetimibe produces a significant reduction in total cholesterol, LDL cholesterol, and triglycerides as well as a small but significant increase in HDL cholesterol. Group: Pharmaceutical. CAS No. 163222-33-1. Pack Sizes: 500 mg. Product ID: NP3280. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe 3-Fluoro Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L27) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. CAS No. 1700622-06-5. Pack Sizes: 25 mg. Product ID: B0026-471386. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe-[d4] | Ezetimibe-[d4] is the labelled analogue of Ezetimibe. Ezetimibe is a cholesterol absorption inhibitor. Group: Pharmaceutical. CAS No. 1093659-89-2. Pack Sizes: 10 mg. Product ID: BLP-012349. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Dehydoxy Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L16) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. CAS No. 204589-58-2. Pack Sizes: 50 mg. Product ID: B2694-471390. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Desfluoro Methyl Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L30) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. CAS No. 1700622-07-6. Pack Sizes: 10 mg. Product ID: B0026-471387. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Fluoro Isomer | A stereoisomer of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L9) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. CAS No. 1798008-25-9. Pack Sizes: 5 mg. Product ID: B0026-471388. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Impurities | Ezetimibe Impurities, integral to the biomedical sector, serve a crucial function in upholding the purity and efficacy of Ezetimibe, a cholesterol-lowering pharmaceutical agent. Through meticulous identification and quantification, these impurities ensure enhanced drug safety and rigorous adherence to pharmaceutical norms, thus aiding cardiovascular disease management efforts. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Impurity 9 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L43) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. CAS No. 272778-12-8. Pack Sizes: 25 g. Product ID: B2694-089119. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Ketone | Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. CAS No. 191330-56-0. Pack Sizes: 5 mg. Product ID: B0026-351314. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Phenoxy Glucuronide-[d4] | Ezetimibe Phenoxy Glucuronide-[d4] is the labelled analogue of Ezetimibe Phenoxy Glucuronide, which is a metabolite of Ezetimibe. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. CAS No. 1426174-41-5. Pack Sizes: 10 mg. Product ID: BLP-005427. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Tetrahydropyran Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. CAS No. 1296129-15-1. Pack Sizes: 50 mg. Product ID: B0026-471373. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
