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| Product | Description | |
|---|---|---|
| Everolimus, Cyclosporine and Tacrolimus Mix Standard | Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Cyclosporine is an immunopsupressent thought to bind to cyclophilin in T-lymphocytes. Tacrolimus is also an immunosuppressant that blocks T-cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Molecular formula: C53H83NO14/C62H111N11O12/C44H69N. Mole weight: 958.22/1202.61/612.02. Custom synthesis is available. Send your inquiries for more information. |  London |
| Evofosfamide | Evofosfamide is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. Group: Pharmaceutical. Alternative Names: TH-302; TH 302; TH302; 2-bromo-N-[(2-bromoethylamino)-[(3-methyl-2-nitroimidazol-4-yl)methoxy]phosphoryl]ethanamine. CAS No. 918633-87-1. Pack Sizes: 50 mg. Product ID: B0084-460516. Molecular formula: C9H16Br2N5O4P. Mole weight: 449.04. Custom synthesis is available. Send your inquiries for more information. | London |
| Evolitrine | Evolitrine is an alkaloid isolated from Fructus Evodiae. Group: Pharmaceutical. Alternative Names: Evolitrin; 4,7-dimethoxyfuro[2,3-b]quinoline. CAS No. 523-66-0. Pack Sizes: 10 mg. Product ID: B2703-292493. Molecular formula: C13H11NO3. Mole weight: 229.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Evoxine | Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides and Teclea gerrardii. Group: Pharmaceutical. Alternative Names: (+)-1-[(4,8-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy]-3-methyl-2,3-butanediol. CAS No. 522-11-2. Pack Sizes: 1 mg. Product ID: B0005-474792. Molecular formula: C18H21NO6. Mole weight: 347.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Evron Brilliant Blue R Dye | Evron Brilliant Blue R Dye - Acid Blue 80, Dyes and Indicators. Mistral Industrial Chemicals our speciality is supplying Technical grade & Industrial grade chemicals in sizes from: 1Kg to 25Kg. We can also supply products in barrels & multiple bags / pallets. | Mistral Lab Supplies Northern Ireland |
| EW-7197 | EW-7197 is a potent and selective ALK5 inhibitor, displaying antimetastatic and anticancer effects. It inhibits TGF-β/Smad signaling, and abrogates TGF-β1-induced tumor cell migration and invasion. EW-7197 inhibits breast cancer metastasis to the lung. EW-7197 prolongs the life span of BALB/c 4T1 mice via inhibition of EMT. EW-7197 inhibits metastasis and enhances the activity of cytotoxic T lymphocytes (CTLs) in 4T1 orthotopic grafted mice. Group: Pharmaceutical. Alternative Names: Vactosertib; N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine. CAS No. 1352608-82-2. Pack Sizes: 50 mg. Product ID: B0084-462343. Molecular formula: C22H18FN7. Mole weight: 399.433. Custom synthesis is available. Send your inquiries for more information. | London |
| Exatecan Mesylate | Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting the religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogs. Group: Pharmaceutical. Alternative Names: DX 8951 mesylate; (1S,9S)-1-Amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-10H,13H-benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione mesylate; 10H,13H-Benzo(de)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-10,13-dione, 1-amino-9-ethyl-5-fluoro-1,2,3,9,12,15-hexahydro-9-hydroxy-4-methyl-, (1S-trans)-, mesylate (1:1); NSC-829066 mesylate. CAS No. 169869-90-3. Pack Sizes: 500 mg. Product ID: BBF-04655. Molecular formula: C25H26FN3O7S. Mole weight: 531.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Excisanin A | Excisanin A is a natural diterpenoid compound found in several plants. Group: Pharmaceutical. Alternative Names: 1alpha,7alpha,12alpha,14beta-Tetrahydroxy-ent-kaur-16-en-15-one. CAS No. 78536-37-5. Pack Sizes: 5 mg. Product ID: NP1445. Molecular formula: C20H30O5. Mole weight: 350.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Excisanin B | Excisanin B is extracted from the herbs of Isodon japonicus. It inhibits production of nitric oxide in LPS-induced murine macrophage RAW264.7 cells. Group: Pharmaceutical. Alternative Names: 1alpha,7alpha,14beta-Trihydroxy-12alpha-acetoxykaura-16-ene-15-one. CAS No. 78536-36-4. Pack Sizes: 5 mg. Product ID: NP1397. Molecular formula: C22H32O6. Mole weight: 392.49. Custom synthesis is available. Send your inquiries for more information. | London |
| Exenatide acetate | Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Group: Pharmaceutical. Alternative Names: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L | London |
| Exendin 3 (9-39) | Exendin (9-39) is a specific and competitive glucagon-like peptide-1receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Exendin (9-39) inhibits insulin release and cAMP production caused by GLP-1 (7-36), exendin-3, and exendin-4. Group: Pharmaceutical. Alternative Names: Exendin 9-39; Exendin 9 39; H-DL-Asp-DL-Leu-DL-Ser-DL-Lys-DL-Gln-DL-Met-DL-Glu-DL-Glu-DL-Glu-DL-Ala-DL-Val-DL-Arg-DL-Leu-DL-Phe-DL-xiIle-DL-Glu-DL-Trp-DL-Leu-DL-Lys-DL-Asn-Gly-Gly-DL-Pro-DL-Ser-DL-Ser-Gly-DL-Ala-DL-Pro-DL-Pro-DL-Pro-DL-Ser-NH2; DL-alpha-aspartyl-DL-leucyl-DL-seryl-DL-lysyl-DL-glutaminyl-DL-methionyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alpha-glutamyl-DL-alanyl-DL-valyl-DL-arginyl-DL-leucyl-DL-phenylalanyl-DL-isoleucyl-DL-alpha-glutamyl-DL-tryptophyl-DL-leucyl-DL-lysyl-DL-asparagyl-glycyl-glycyl-DL-prolyl-DL-seryl-DL-seryl-glycyl-DL-alanyl-DL-prolyl-DL-prolyl-DL-prolyl-DL-serinamide. CAS No. 133514-43-9. Pack Sizes: 1 mg. Product ID: BAT-006203. Molecular formula: C149H234N40O47S. Mole weight: 3369.76. Custom synthesis is available. Send your inquiries for more information. | London |
| Exherin | Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibition of tumor cell growth, and the induction of tumor cell and endothelial cell apoptosis. N-cadherin, a cell- surface transmembrane glycoprotein of the cadherin superfamily of proteins involved in calcium-mediated cell-cell adhesion and signaling mechanisms; may be upregulated in some aggressive tumors and the endothelial cells and pericytes of some tumor blood vessels. Group: Pharmaceutical. Alternative Names: NSC729477; ADH-1; NSC7 29477; ADH 1; NSC-729477; ADH1. CAS No. 229971-81-7. Pack Sizes: 10 mg. Product ID: BAT-010745. Molecular formula: C22H34N8O6S2. Mole weight: 570.69. Custom synthesis is available. Send your inquiries for more information. | London |
| Exosomes | Exosomes are small natural membrane vesicles released by a wide variety of cell types into the extracellular compartment by exocytosis. Exosomes are the smallest EVs and are of particular interest in the tumor microenvironment (TME), where they have been shown to directly mediate angiogenesis, tumor metastasis, and immunosuppression. Group: Pharmaceutical. Pack Sizes: 10 ml. Product ID: B1370-087452. Custom synthesis is available. Send your inquiries for more information. | London |
| Exo-Tetrahydrodicyclopentadiene | Exo-Tetrahydrodicyclopentadiene (CAS# 2825-82-3 ) is a useful research chemical. Group: Pharmaceutical. Alternative Names: exo-Trimethylenenorbornane; (3aR,4S,7R,7aS)-rel-Octahydro-1H-4,7-methanoindene; JP-10. CAS No. 2825-82-3. Pack Sizes: 25 g. Product ID: B2699-178550. Molecular formula: C10H16. Mole weight: 136.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Exoticin | Exoticin isolated from the herbs of Murraya exotica. Group: Pharmaceutical. Alternative Names: 3,3',4',5,5',6,7,8-octamethoxyflavone; 3,5,6,7,8-Pentamethoxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-on e. CAS No. 13364-94-8. Pack Sizes: 1 mg. Product ID: NP2121. Molecular formula: C23H26O10. Mole weight: 462.5. Custom synthesis is available. Send your inquiries for more information. | London |
| EXPANSION ADAPTER SOCKET | EXPANSION ADAPTER SOCKET, Suppliers of laboratory chemicals wanted |  |
| EXPANSION ADAPTOR SOCKET | EXPANSION ADAPTOR SOCKET, UK suppliers of laboratory chemicals wanted | |
| EXTRACTION THIMBLES | EXTRACTION THIMBLES, UK suppliers of laboratory chemicals wanted | |
| Exxsol D100 | Exxsol D100. At Tan International we supply a wide range of products covering all industry sectors |  Scotland |
| EYEBRIGHT | EYEBRIGHT - Our signature range of liquid botanical extracts |  England, Scotland |
| Eyeliss | Eyeliss is a cosmetic indegredient that has been used to relieve puffiness under eye bags and reduce dark circles beneath the eyes. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: BAT-006233. Custom synthesis is available. Send your inquiries for more information. | London |
| EYESHIELD, JUNIOR | EYESHIELD, JUNIOR, Suppliers of laboratory chemicals wanted | |
| Ezatiostat | Ezatiostat is a glutathione analog that acts as an inhibitor of glutathione S-transferase (GST) P1-1. TLK117, the active form of ezatiostat, inhibits GSTP1-1, resulting in phosphorylation of JNK, restoring JNK-mediated cellular proliferation and differentiation signaling pathways. Group: Pharmaceutical. Alternative Names: Telintra; Gamma-Glu-S-BzCys-PhGly diethyl ester; TLK-199; TLK 199. CAS No. 168682-53-9. Pack Sizes: 25 mg. Product ID: BAT-010079. Molecular formula: C27H35N3O6S. Mole weight: 529.652. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C24H21F2NO3. CAS No. 163222-33-1. Prepack ID : 74798364-1g. Molecular Weight : 409.4. |  |
| Ezetimibe | Ezetimibe produces a significant reduction in total cholesterol, LDL cholesterol, and triglycerides as well as a small but significant increase in HDL cholesterol. Group: Pharmaceutical. Alternative Names: SCH 58235; SCH-58235; SCH58235; Ezetimibe, Zetia, Ezetrol. CAS No. 163222-33-1. Pack Sizes: 500 mg. Product ID: NP3280. Molecular formula: C24H21F2NO3. Mole weight: 409.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe 3-Fluoro Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L27) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: Ezetimibe m-Fluoroaniline analog; (3R,4S)-1-(3-Fluorophenyl)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; N-Des(4-Fluorophenyl)-N-(3-fluorophenyl) Ezetimibe; (3R,4S)-1-(3-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; m-Fluoroaniline isomer of Ezetimibe; 3-Fluoro Ezetimibe. CAS No. 1700622-06-5. Pack Sizes: 25 mg. Product ID: B0026-471386. Molecular formula: C24H21F2NO3. Mole weight: 409.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe-[d4] | Ezetimibe-[d4] is the labelled analogue of Ezetimibe. Ezetimibe is a cholesterol absorption inhibitor. Group: Pharmaceutical. Alternative Names: Ezetimibe D4; (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl-d4)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone; Sch-58235-d4. CAS No. 1093659-89-2. Pack Sizes: 10 mg. Product ID: BLP-012349. Molecular formula: C24H17D4F2NO3. Mole weight: 413.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Dehydoxy Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L16) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: 3-Dehydroxy Ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-2-azetidinone. CAS No. 204589-58-2. Pack Sizes: 50 mg. Product ID: B2694-471390. Molecular formula: C24H21F2NO2. Mole weight: 393.44. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Deprotected Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L13) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: (S)-3-((2R,5S)-5-(4-fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-hydroxyphenyl)methyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one. CAS No. 1185883-40-2. Pack Sizes: 20 mg. Product ID: B1370-175318. Molecular formula: C33H30F2N2O5. Mole weight: 572.61. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Desfluoro Methyl Impurity | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L30) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: 4"DeFluoro-4"methyl-ezetimibe; (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-hydroxy-3-(p-tolyl)propyl)-4-(4-hydroxyphenyl)azetidin-2-one. CAS No. 1700622-07-6. Pack Sizes: 10 mg. Product ID: B0026-471387. Molecular formula: C25H24FNO3. Mole weight: 405.47. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Impurity 9 | An impurity of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L43) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: (S)-3-((2R,5S)-5-(4-Fluorophenyl)-2-((S)-((4-fluorophenyl)amino)(4-((trimethylsilyl)oxy)phenyl)methyl)-5-((trimethylsilyl)oxy)pentanoyl)-4-phenyloxazolidin-2-one; 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone. CAS No. 272778-12-8. Pack Sizes: 25 g. Product ID: B2694-089119. Molecular formula: C39H46F2N2O5Si2. Mole weight: 716.98. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Ketone | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one; (3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-2-azetidinone; EZM-K; Ezetimibe 3-Oxo Impurity; 2-Azetidinone, 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)-, (3R-trans)-. CAS No. 191330-56-0. Pack Sizes: 5 mg. Product ID: B0026-351314. Molecular formula: C24H19F2NO3. Mole weight: 407.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Ezetimibe Phenoxy Glucuronide-[d4] | Ezetimibe Phenoxy Glucuronide-[d4] is the labelled analogue of Ezetimibe Phenoxy Glucuronide, which is a metabolite of Ezetimibe. Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Group: Pharmaceutical. Alternative Names: Ezetimibe D4 Phenoxy Glucuronide. CAS No. 1426174-41-5. Pack Sizes: 10 mg. Product ID: BLP-005427. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57. Custom synthesis is available. Send your inquiries for more information. | London |
