BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Binimetinib | Binimetinib is an oral, highly selective MEK inhibitor. Group: Pharmaceutical. CAS No. 606143-89-9. Pack Sizes: 300 mg. Product ID: B0084-455720. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Binodenoson | Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor agonist. It is used to diagnose coronary artery disease. Uses: Purinergic p1 receptor agonists. Group: Pharmaceutical. CAS No. 144348-08-3. Pack Sizes: 10 mg. Product ID: B1370-078439. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BIO | BIO is a potent and reversible inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/&beta. BIO enhances reprogramming of mouse fibroblasts, neural stem cells, and thymocytes to induced pluripotent stem (iPS) cells. It also promotes differentiation of cardiomyocytes from human ES and iPS cells. Group: Pharmaceutical. CAS No. 667463-62-9. Pack Sizes: 25 mg. Product ID: B2693-286135. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BIO 1211 | BIO 1211 is a selective and high affinity integrin α4β1 (Very Late Antigen 4; VLA-4) inhibitor with 200-fold selectivity for the activated form of α4β1 (KD = 70 pM; IC50 = 0.004 μM). Group: Pharmaceutical. CAS No. 187735-94-0. Pack Sizes: 50 mg. Product ID: BAT-010232. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BIO 5192 | BIO 5192 is a selective and potent inhibitor of integrin α4β1 (Very Late Antigen-4; VLA-4) (Kd < 10 pM) with selectivity for α4β1 over a range of other integrins (IC50 values are 1.8, 138, 1053,> 500 and > 10,000 nM for α4β1, α9β1, α2β1, α4β7 and αIIbβ3, respectively). BIO 5192 causes a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels. Group: Pharmaceutical. CAS No. 327613-57-0. Pack Sizes: 10 mg. Product ID: B2693-119144. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bioallethrin Impurities | Bioallethrin Impurities, as integral byproducts of bioallethrin synthesis, undergo rigorous examination within biomedical domains to evaluate synthetic pyrethroids' safety profiles and therapeutic efficacy. Their critical function in pharmaceutical realms lies in certifying that insecticidal formulations remain devoid of detrimental residues, thereby safeguarding therapeutic applications and ecological integrity. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biopterin Impurities | Biopterin Impurities, essential components in evaluating pharmaceutical integrity, are fundamental in research and quality assurance realms. Their significance lies in the exploration of medicinal synthesis and stability for conditions like phenylketonuria and neurological maladies, impacting tetrahydrobiopterin, a pivotal cofactor in neurotransmitter biosynthetic processes. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biorobin | Biorobin is a natural flavonoid found in the herbs of Cassia occidentalis. Group: Pharmaceutical. CAS No. 17297-56-2. Pack Sizes: 1 mg. Product ID: NP2098. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biotiin-Amylin, human amidated | Biotiin-Amylin, human amidated. Group: Pharmaceutical. CAS No. 1678415-18-3. Pack Sizes: 1 mg. Product ID: BAT-006255. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (+)-Biotin azidopropylamide | (+)-Biotin azidopropylamide, a scientific compound, is a highly effective labeling agent for proteins aimed at facilitating their affinity purification and detection. Its multifaceted role spans across understanding protein-protein interactions, molecular biology, and oncology whereby its application in the development of diagnostic assays for cancer has proven resourceful. Group: Pharmaceutical. CAS No. 908007-17-0. Pack Sizes: 100 mg. Product ID: B2699-168900. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biotin Impurities | Biotin Impurities are crucial in the development and quality control of pharmaceuticals aimed at treating multiple sclerosis and metabolic disorders. These impurities help ensure the purity and efficacy of biotin-based treatments, fostering advancements in therapies targeting neurological and metabolic disease pathways. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biotinoyl tripeptide-1 | Biotinoyl tripeptide-1 is a peptide beneficial for hair conditioning. Biotinoyl tripeptide-1 is also used in anti-aging cosmetics. Biotinoyl tripeptide-1 is a tripeptide that combines vitamin H with the Matrikine series GHK. Biotinoyl tripeptide-1 can stimulate the synthesis of collagen IV and laminin 5, and fix hair in the dermal hair follicle to prevent hair loss. Uses: biotinylated tripeptide-1, also known as vitamin h peptide, plays a vital role in drug discovery due to its unique properties and potential therapeutic applications. this peptide is composed of biotin, a water-soluble b vitamin that is essential for various biochemical processes, and a tripeptide composed of three amino acids. in drug discovery, biotinylated tripeptide-1 has received attention. Group: Pharmaceutical. CAS No. 299157-54-3. Pack Sizes: 1 g. Product ID: BAT-010782. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biotin-PEG4-Picolyl azide | Biotin-PEG4-Picolyl azide is a polyethylene glycol (PEG)-based PROTAC linker. Biotin-PEG4-Picolyl azide can be used in the synthesis of a series of PROTACs. Group: Pharmaceutical. CAS No. 2222687-71-8. Pack Sizes: 25 mg. Product ID: BP-501289. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biotin-XX Tyramide | The thieno[3,4-d]imidazol-4-yl moiety embedded within this newly synthesized compound harbors the potential for therapeutic utility against neurological disorders. However, its intricate structure demands rigorous evaluation of its safety and efficacy as a potential drug prior to clinical translation. Despite preliminary implications, extensive studies are necessary to determine the full scope of its therapeutic potential. Group: Pharmaceutical. CAS No. 851113-28-5. Pack Sizes: 10 mg. Product ID: B2699-010024. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biotinyl Tyramide | Biotinyl Tyramide is a biotin derivative used as a reagent for signal amplification in IHC and in situ hybridization (ISH). Group: Pharmaceutical. CAS No. 41994-02-9. Pack Sizes: 1 g. Product ID: B1370-118881. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biperiden Impurities | Biperiden Impurities hold a crucial position in the biomedical domain, facilitating stringent quality assurance and exploratory analyses related to the anticholinergic agent Biperiden. These impurities, extensively applied in Parkinsons therapy, unveil critical data on drug stability, potency, and safety, thereby deepening comprehension of therapeutic efficacy in the management of movement disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biphenyl Impurities | Biphenyl Impurities occupy a critical niche in pharmaceutical innovation, intricately involved in the rigorous evaluation of drug stability and potency. Their essential function in quality assurance fortifies the synthesis of therapeutics, particularly antihypertensives and antipsychotics, ensuring pharmacological efficacy and safety through meticulous management of molecular discrepancies within intricate pharmaceutical systems. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Birinapant | Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity. As a SMAC mimetic and IAP antagonist, TL32711 binds to and inhibits the activity of IAPs, such as X chromosome-linked IAP (XIAP) and cellular IAPs 1 and 2. Since IAPs shield cancer cells from the apoptosis process, this agent may restore and promote the induction of apoptosis through apoptotic signaling pathways in cancer cells. IAPs are overexpressed by many cancer cell types and suppress apoptosis by binding and inhibiting active caspases-3, -7 and -9 via their baculoviral lAP repeat (BIR) domains. Check for active clinical trials or closed clinical trials using this agent. Group: Pharmaceutical. CAS No. 1260251-31-7. Pack Sizes: 100 mg. Product ID: B0084-462223. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bis[1,3-bis(h2-ethenyl)-1,1,3,3-tetramethyldisiloxane]platinum | Bis[1,3-bis(h2-ethenyl)-1,1,3,3-tetramethyldisiloxane]platinum. Group: Pharmaceutical. CAS No. 81032-58-8. Pack Sizes: 10 mg. Product ID: B0001-151999. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BIS(1-BUTYLPENTYL) DECANE-1,10-DIYL DIGLUTARATE | Abbreviated as Sec or U, in older publications also as Se-Cys, as a building block of selenoproteins, this 21st proteinogenic amino acid exists naturally in three domains of life, but not in every lineage. Uses: Used for the characterization of total sodium concentration in human blood plasma; also used for the preparation of nitrite-selective membrane electrode, used for the potentiometric determination of nad(p)h coenzymes. Group: Pharmaceutical. CAS No. 101342-76-1. Pack Sizes: 1 g. Product ID: B0001-236189. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite | A useful phosphorylating reagent. Group: Pharmaceutical. CAS No. 102690-88-0. Pack Sizes: 5 g. Product ID: B2699-159097. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bis(2-ethylhexyl) carbonate | Bis(2-ethylhexyl) carbonate (CAS# 14858-73-2 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 14858-73-2. Pack Sizes: 10 mg. Product ID: B2699-272678. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| bis-(4-(1,1,3,3-Tetramethylbutyl)phenyl) ether | Bis-(4-(1,1,3,3-Tetramethylbutyl)phenyl) ether is a highly valuable compound for the pharmaceutical industry due to its significance as a key intermediate. The synthesis of drugs and compounds for the treatment of a myriad of diseases depends on the use of bis-(4-(1,1,3,3-Tetramethylbutyl)phenyl) ether. Its versatility lies in its utilization as a crucial material in developing anti-inflammatory, antiviral agents, and inhibition of enzymes and receptors. The incorporation of this compound in drug formulations has immense implications for the healthcare industry. Group: Pharmaceutical. CAS No. 101-58-6. Pack Sizes: 10 mg. Product ID: B2699-273506. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bis(4-fluorophenyl)phenylphosphine oxide | Catalyst for hydroformylation reactions Used for preparation of chlorine-tolerant polymers for desalination Crosslinking agent in preparation of polymer electrolyte membranes for fuel cell applications. Group: Pharmaceutical. CAS No. 54300-32-2. Pack Sizes: 5 g. Product ID: B2699-026488. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| bis[6-(5,6-dihydrochelerythrinyl)]amine | Bis[6-(5,6-dihydrochelerythrinyl)]amine is found in Zanthoxylum nitidum, which shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus. Group: Pharmaceutical. CAS No. 165393-48-6. Pack Sizes: 5 mg. Product ID: B2703-334736. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisabola-3,10-dien-2-one | Bisabola-3,10-dien-2-one is isolated from the leaves of Alpinia intermedia. Group: Pharmaceutical. CAS No. 61432-71-1. Pack Sizes: 1 mg. Product ID: NP5981. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisabolol Impurities | Bisabolol Impurities play a critical role in the quality control and formulation of pharmaceuticals targeting inflammatory disorders and skin ailments. These impurities, when thoroughly analyzed, ensure the purity and efficacy of active bisabolol, which is recognized for its soothing, antioxidant, and potential antimicrobial properties. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisacodyl Impurities | Bisacodyl Impurities, essential for meticulous laxative drug quality assurance, play a crucial role in scrutinizing and confirming Bisacodyl's efficacy and safety as a constipation remedy. Investigating such impurities enriches drug development, advancing gastrointestinal treatment strategies and refining synthetics, thereby improving pharmaceutical results with rigorous scientific accuracy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bis-acyclovir | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Group: Pharmaceutical. CAS No. 1797131-64-6. Pack Sizes: 5 mg. Product ID: B0093-466137. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisandrographolide A | Bisandrographolide A is a natural diterpenoid found in the herbs of Andrographis paniculata (Burm. f.) Nees. The compound can activate TRPV4 channels and play a role in some of the effects of Andrographis extract described in traditional medicine. Group: Pharmaceutical. CAS No. 160498-00-0. Pack Sizes: 1 mg. Product ID: NP1631. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bismuth Impurities | Bismuth Impurities, although typically undesired, play a crucial role in the biomedical industry for improving the purification process of pharmaceutical bismuth compounds. They are pivotal in refining bismuth-based drugs, notably used for treating peptic ulcers and bacterial infections like Helicobacter pylori, ensuring high efficacy and safety of the medications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bismuth iodide | Bismuth iodide. Group: Pharmaceutical. CAS No. 7787-64-6. Pack Sizes: 300 g. Product ID: B1370-043046. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bismuth Subsalicylate | Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2. Uses: Antidiarrheals. Group: Pharmaceutical. CAS No. 14882-18-9. Pack Sizes: 1 kg. Product ID: B1370-059261. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bismuth telluride | Bismuth telluride. Group: Pharmaceutical. CAS No. 1304-82-1. Pack Sizes: 250 g. Product ID: B1370-048145. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bis(N-diazo)-tris(O-acetyl)-2-deoxystreptamine | Bis(N-diazo)-tris(O-acetyl)-2-deoxystreptamine (CAS# 90852-19-0 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 90852-19-0. Pack Sizes: 5 g. Product ID: B2699-331519. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| bis-N-Succinimidyl diglycolic acid | Bis-N-Succinimidyl diglycolic acid, a widely utilized cross-linking reagent, plays a pivotal role in biomedicine. Its reaction with proteins' primary amines leads to covalent binding, which is instrumental in exploring protein-protein interactions. This reagent is also an indispensable component in the development of drug delivery and biomaterials to combat various diseases, including cancer. Group: Pharmaceutical. CAS No. 373614-12-1. Pack Sizes: 100 g. Product ID: B2699-237515. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisoprolol Acid Impurity | Bisoprolol Acid Impurity is a major metabolite and impurity of Bisoprolol, a medication used for the treatment of hypertension, heart failure and other heart diseases. Group: Pharmaceutical. CAS No. 72570-70-8. Pack Sizes: 10 mg. Product ID: B2694-467604. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisoprolol EP Impurity A | isoprolol EP Impurity A is a metabolite of Metoprolol and Bisoprolol. Bisoprolol is a medication used for the treatment of hypertension, heart failure and other heart diseases. Group: Pharmaceutical. CAS No. 62572-93-4. Pack Sizes: 25 mg. Product ID: B2694-467603. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisoprolol EP Impurity G | An impurity of Bisoprolol, a medication used for the treatment of hypertension, heart failure and other heart diseases. Group: Pharmaceutical. CAS No. 1215342-36-1. Pack Sizes: 10 mg. Product ID: B2694-467607. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisoprolol EP Impurity K | Bisoprolol EP Impurity K is an impurity of Bisoprolol, a medication used for the treatment of hypertension, heart failure and other heart diseases. Group: Pharmaceutical. CAS No. 864544-37-6. Pack Sizes: 5 mg. Product ID: B2694-467608. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisoprolol EP Impurity L hydrochloride | An impurity of Bisoprolol. Bisoprolol is a medication used for the treatment of hypertension, heart failure and other heart diseases. Group: Pharmaceutical. CAS No. 1956321-87-1. Pack Sizes: 10 mg. Product ID: B0149-007248. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisoprolol hemifumarate | Bisoprolol is a beta-adrenoceptor blocking drug (beta-blocker). More specifically, it is a selective type β1 adrenergic receptor blocker. Uses: Antihypertensive agents. Group: Pharmaceutical. CAS No. 104344-23-2. Pack Sizes: 500 mg. Product ID: NP3369. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisoprolol Impurities | Bisoprolol Impurities are crucial in the biomedical industry for ensuring the quality and safety of bisoprolol formulations. They assist in the analytical characterization and validation processes during the development of bisoprolol, a beta-blocker used effectively in the treatment of hypertension and heart diseases like chronic heart failure. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bis-PEG1-NHS ester | Bis-PEG1-NHS ester is a non-cleavable 1-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Group: Pharmaceutical. CAS No. 65869-64-9. Pack Sizes: 100 mg. Product ID: BADC-00382. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisphenol A bis(2,3-dihydroxypropyl) ether | Applications: Bisphenol A Bis(2,3-dihydroxypropyl) ether is used as a standard for determining toxic monomers released from polymers of the inner coating of cans. Group: Pharmaceutical. CAS No. 5581-32-8. Pack Sizes: 1 g. Product ID: B2699-189643. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bisphenol Impurities | Bisphenol Impurities, integral to biomedical safety evaluations, provide crucial insights into potential endocrine-disrupting effects within pharmaceuticals and medical devices. While not therapeutic, these impurities critically underpin quality control processes, ensuring adherence to health regulations and addressing concerns related to hormonal-related pathologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bis(tributylammonium) pyrophosphate | Bis(tributylammonium) pyrophosphate. Group: Pharmaceutical. CAS No. 5975-18-8. Pack Sizes: 10 g. Product ID: B1370-012679. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bivalirudin Impurities | Bivalirudin Impurities occupy a central role in the biomedical field, particularly within analytical evaluations that ascertain the purity and integrity of bivalirudin, a critical anticoagulant for percutaneous coronary interventions. Through meticulous quality control, they unveil potential degradation pathways, thereby fortifying the safety and therapeutic effectiveness of bivalirudin treatments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BKM120 | BKM120, also called as buparlisib or NVP-BKM120, activity in a range of preclinical cancer models, specifically inhibits class I PI3K isoforms, which blocks p110α (IC50 = 52 nM), p110β (IC50 = 166 nM), p110δ (IC50 = 116 nM) and p110γ (IC50 = 262 nM). BKM120 displays little sensitive to Class III and Class IV PI3K's or PI4K. Group: Pharmaceutical. CAS No. 944396-07-0. Pack Sizes: 200 mg. Product ID: B0084-438224. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BKT140 | BKT140 is a CXCR4 inhibitor with antineoplastic activity. Studies demonstrated that BKT140 showed a robust mobilization of white blood cells (WBC) and hematopoietic stem cells (HSC). Group: Pharmaceutical. CAS No. 664334-36-5. Pack Sizes: 5 mg. Product ID: BAT-006144. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BL-918 | BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1). It induces cytoprotective autophagy for Parkinson's disease treatment. It protected against MPTP-induced motor dysfunction and loss of dopaminergic neurons by targeting ULK1-modulated autophagy in mouse models of PD. Group: Pharmaceutical. CAS No. 2101517-69-3. Pack Sizes: 25 mg. Product ID: B2693-291256. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (-)-Blebbistatin | (-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Group: Pharmaceutical. CAS No. 856925-71-8. Pack Sizes: 10 mg. Product ID: B0084-259276. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bleomycin sulfate | Bleomycin sulfate is a glycopeptide antibiotic isolated from streptomyces verticillus. It intercalates and cleaves DNA and RNA, resulting in their synthesis suppression, which can be used as an antineoplastic agent. Group: Pharmaceutical. CAS No. 9041-93-4. Pack Sizes: 100 mg. Product ID: BBF-04214. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Blinin | Blinin is a diterpene originally isolated from C. blini. Uses: Antimalarial. Group: Pharmaceutical. CAS No. 125675-09-4. Pack Sizes: 5 mg. Product ID: B2703-464706. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Blonanserin Impurities | Blonanserin Impurities, emerging as critical residuals during blonanserin synthesis, are pivotal in pharmaceutical exploration. Their analysis enhances comprehension of blonanserin's therapeutic efficacy in schizophrenia and psychotic disorders, safeguarding medicinal safety and efficacy through detailed profiling and strategic reduction of detrimental contaminant interactions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BLU-554 | BLU-554 is a potent and selective inhibitor of fibroblast growth factor receptor 4 (FGFR4) (IC50 = 5 nM), which is promisingly to be used for the treatment of hepatocellular carcinoma and cholangiocarcinoma. Group: Pharmaceutical. CAS No. 1707289-21-1. Pack Sizes: 10 mg. Product ID: B0084-008122. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BLU-667 | BLU-667 (Pralsetinib) is a highly effective and selective RET inhibitor. It has an IC50 of 0.3-0.4 nM for the fusion of WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET. Group: Pharmaceutical. CAS No. 2097132-94-8. Pack Sizes: 5 mg. Product ID: B2693-373106. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BLU9931 | BLU9931 is a potent and irreversible small-molecule inhibitor of FGFR4, as a targeted therapy to treat patients with HCC whose tumors have an activated FGFR4 signaling pathway. BLU9931 is exquisitely selective for FGFR4 versus other FGFR family members and all other kinases. Group: Pharmaceutical. CAS No. 1538604-68-0. Pack Sizes: 25 mg. Product ID: B0084-470871. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Blumeatin | Blumeatin is found in tea and is extracted from the herbs of Blumea balsamifera. It can enhance adipocyte differentiation by increasing triglyceride levels in 3T3L1 cells. It also can increase the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes GLUT4 and aP2. It inhibits the increase of liver triglyceride and serum alanine aminotransferase, and increases serum beta-lipoprotein, liver glycogen and triglyceride content in CCl4-intoxicated rats, thus shorten the pentobarbital sleeping time in CCl4-intoxicated mice. It shows free radical scavenging activity, xanthine oxidase (XO) inhibitory activity and antioxidant properties. It can protect liver against injury induced by CCl4 and TAA. Group: Pharmaceutical. CAS No. 118024-26-3. Pack Sizes: 10 mg. Product ID: B1370-267733. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BLZ945 | BLZ945 is an orally active, potent and selective CSF-1R inhibitor, which inhibits CSF-1R activity with an IC50 of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRb). Group: Pharmaceutical. CAS No. 953769-46-5. Pack Sizes: 50 mg. Product ID: B0084-463485. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BML-277 | BML-277 is a selective APT-competitive inhibitor of the DNA damage response signaling enzyme CHK2 ( IC50 =15 nM). Uses: A selective apt-competitive inhibitor. Group: Pharmaceutical. CAS No. 516480-79-8. Pack Sizes: 50 mg. Product ID: B0084-300068. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BML-284 | BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro. Uses: Bml-284 may be a useful tool in the study of physiological processes that involve the wnt pathway. Group: Pharmaceutical. CAS No. 853220-52-7. Pack Sizes: 25 mg. Product ID: B0084-474867. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BMS303141 | BMS 303141 is a cell-permeable, 2-hydroxy-N-arylbenzenesulfonamide that inhibits ACL with an IC50 value of 0.13 μM. BMS 303141 has been reported to reduce weight gain and lower plasma cholesterol, triglycerides, and glucose in a mouse model of hyperlipidemia. Group: Pharmaceutical. CAS No. 943962-47-8. Pack Sizes: 100 mg. Product ID: B2693-462267. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BMS 309403 | BMS 309403 is a potent, selective and cell-permeable inhibitor of adipocyte fatty acid binding protein (FABP4) with a Ki of less than 2 nM, which exhibits Ki values of 250 nM for FABP3 and 350 nM for FABP5. BMS 309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS 309403 is a biphenyl azole inhibitor against fatty acid binding protein 4 (FABP4) and regarded as a lead compound for effective treatment of obesity related cardio-metabolic diseases. Group: Pharmaceutical. CAS No. 300657-03-8. Pack Sizes: 100 mg. Product ID: B1370-105220. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-663068 | BMS-663068 is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection. It is a prodrug for BMS-626529, which binds to the viral envelope glycoprotein gp120 and interferes with attachment of the virus to the cellular CD4 receptor. Group: Pharmaceutical. CAS No. 864953-29-7. Pack Sizes: 100 mg. Product ID: B0084-463659. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-777607 | BMS-777607 is a novel prodrug of the dual Met/VEGFR-2 inhibitor. It shows antitumor activity, inducing apoptosis and decreasing proliferation and migration. Group: Pharmaceutical. CAS No. 1025720-94-8. Pack Sizes: 50 mg. Product ID: B2693-456491. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-779788 | BMS-779788 is a LXR partial agonist with IC50 values of 68 nM and 14 nM for LXRα and LXRβ respectively. BMS-779788 induces LXR target genes in blood in vivo with EC50 value of 610 nM, and significantly increases plasma triglyceride and LDL cholesterol. Group: Pharmaceutical. CAS No. 918348-67-1. Pack Sizes: 25 mg. Product ID: B0084-284850. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-791325 HCl | BMS-791325 HCl is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase. BMS-791325 inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 at 50% inhibitory concentrations (IC50 < 28 nM). In cell culture, BMS-791325 inhibited replication of HCV subgenomic replicons representing genotypes 1a and 1b at 50% effective concentrations (EC50s) of 3 nM and 6 nM, respectively, with similar (3 to 18 nM) values for genotypes 3a, 4a, and 5a. BMS-791325 was found to have distinguishing antiviral, safety, and pharmacokinetic properties that resulted in its selection for clinical evaluation. BMS-791325 is currently under Phase III trials. Group: Pharmaceutical. CAS No. 958002-36-3. Pack Sizes: 5 mg. Product ID: B0084-462269. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-794833 | BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM. Group: Pharmaceutical. CAS No. 1174046-72-0. Pack Sizes: 25 mg. Product ID: B2693-286366. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BMS-911543 | BMS-911543 is an orally available JAK inhibitor with selectivity for JAK2. It inhibts JAK2, thereby preventing the JAK/STAT (signal transducer and activator of transcription) signaling cascade, including activation of STAT3. This may lead to an induction of tumor cell apoptosis and a decrease in cellular proliferation. Group: Pharmaceutical. CAS No. 1271022-90-2. Pack Sizes: 20 mg. Product ID: B0084-457828. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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