BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Azithromycin EP Impurity C | An impurity of Azithromycin. Azithromycin is an antibiotic for the treatment of bacterial infections including middle ear infections, strep throat, pneumonia, and other sexually transmitted infections. Group: Pharmaceutical. CAS No. 620169-47-3. Pack Sizes: 5 mg. Product ID: B0051-007227. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Azithromycin EP Impurity D | Azithromycin EP Impurity D is an impurity of azithromycin, a macrolide antibiotic used for bacterial infections. Group: Pharmaceutical. CAS No. 612069-26-8. Pack Sizes: 5 mg. Product ID: B0051-002903. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity E | Azithromycin EP Impurity E is one of several different impurities found in the macrolide antibiotic, azithromycin. It can be used as a reference standard for azithromycin impurity tracing. Group: Pharmaceutical. CAS No. 612069-27-9. Pack Sizes: 50 mg. Product ID: B0051-467180. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity F | Azithromycin EP Impurity F is one of several different impurities found in the macrolide antibiotic, azithromycin. It can be used as a trace impurity reference standard. Group: Pharmaceutical. CAS No. 612069-28-0. Pack Sizes: 50 mg. Product ID: B0051-260416. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity G | Azithromycin EP Impurity G is an impurity found in the macrolide antibiotic, azithromycin. It can be used as a standard to trace azithromycin impurities. Group: Pharmaceutical. CAS No. 612069-31-5. Pack Sizes: 25 mg. Product ID: B0051-467181. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity H | Azithromycin EP Impurity H is an impurity found in the macrolide antibiotic, azithromycin. It can be used as a reference standard to trace impurities in azithromycin. Group: Pharmaceutical. CAS No. 612069-30-4. Pack Sizes: 25 mg. Product ID: B0051-462080. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity I | Azithromycin EP Impurity I is an impurity of azithromycin, a macrolide antibiotic used for bacterial infections. Group: Pharmaceutical. CAS No. 172617-84-4. Pack Sizes: 50 mg. Product ID: B0051-467173. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity J | Azithromycin EP Impurity J is a metabolite of the semi-synthetic macrolide antibiotic Azithromycin. Group: Pharmaceutical. CAS No. 117693-41-1. Pack Sizes: 50 mg. Product ID: B0051-300587. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity M | Azithromycin EP Impurity M is a degradation product of Azithromycin. Group: Pharmaceutical. CAS No. 765927-71-7. Pack Sizes: 2.5 mg. Product ID: B0051-467182. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity N | Azithromycin EP Impurity N is a degradation product of Azithromycin. Group: Pharmaceutical. CAS No. 612069-25-7. Pack Sizes: 2.5 mg. Product ID: B0051-467183. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin EP Impurity Q | An impurity of Azithromycin, a macrolide antibiotic effective against bacterial infections. Group: Pharmaceutical. CAS No. 2095879-65-3. Pack Sizes: 10 mg. Product ID: B1370-336159. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azithromycin Impurities | Azithromycin Impurities, essential within macrolide antibiotic quality assurance, act as pivotal reference standards for meticulous evaluation of Azithromycin's purity, potency, and safety profiles. They are crucial in detecting degradation by-products, thereby ensuring therapeutic integrity in addressing bacterial maladies, such as respiratory and skin infections, fortifying pharmaceutical dependability. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azoramide | Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It is a dual-function endoplasmic reticulum (ER) modulator in vitro. It improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones to protect cells against ER stress in multiple systems. It regulates ER folding and secretion capacity without inducing ER stress. It might have the protective effects of enhancing chaperone expression and reducing protein synthesis without inducing cytotoxicity and apoptosis. It showed potent antidiabetic activity in two independent mouse models of obesity by protecting pancreatic β cell function against ER stress and improving insulin sensitivity in vivo. It improves glucose homeostasis in mice with genetic obesity and diet-induced obesity. Group: Pharmaceutical. CAS No. 932986-18-0. Pack Sizes: 100 mg. Product ID: B1370-474920. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azoxystrobin | Azoxystrobin is a systemic fungicide commonly used in agriculture. It is used as an active agent protecting plants and fruit/vegetables from fungal diseases. It inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1. Group: Pharmaceutical. CAS No. 131860-33-8. Pack Sizes: 5 g. Product ID: B0084-467187. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azoxystrobin Impurities | Azoxystrobin Impurities are crucial in the quality control and assurance processes for azoxystrobin production, ensuring the efficacy and safety of this antifungal agent. This compound is instrumental in agricultural and biomedical settings, being meticulously evaluated for its role in combating fungi-related diseases and enhancing antifungal drug formulation. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aztreonam | Aztreonam inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking. It has a very high affinity for penicillin-binding protein-3 and mild affinity for penicillin-binding protein-1a. Aztreonam binds the penicillin-binding proteins of Gram-positive and anaerobic bacteria very poorly and is largely ineffective against them. Group: Pharmaceutical. CAS No. 78110-38-0. Pack Sizes: 5 g. Product ID: B2692-098493. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aztreonam Impurities | Aztreonam Impurities serve as essential reference materials within pharmaceutical research, particularly pivotal for ascertaining the purity and quality of the antibiotic aztreonam. They aid in the detection and quantification of trace compounds, which may influence the drug's safety and efficacy, thereby fortifying treatments against bacterial infections. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aztreonam Impurity A | Aztreonam Impurity A is an metabolite of Aztreonam, a synthetic monocyclic β-lactam antibiotic. Group: Pharmaceutical. CAS No. 87500-74-1. Pack Sizes: 25 mg. Product ID: B2694-467190. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aztreonam impurity D | Aztreonam impurity D is an impurity of Aztreonam. Aztreonam is a monobactam antibiotic used primarily to treat gram-negative bacterial infections. Uses: Aztreonam (a965200). Group: Pharmaceutical. CAS No. 102579-59-9. Pack Sizes: 10 mg. Product ID: B2694-118863. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aztreonam impurity E | Aztreonam impurity E is the (E)-isomer of Aztreonam, a synthetic monocyclic β-lactam antibiotic. Uses: Anti-bacterial agents. Group: Pharmaceutical. CAS No. 99341-02-3. Pack Sizes: 10 mg. Product ID: B2694-355144. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aztreonam impurity F | Aztreonam Ethyl Ester is used in the HPLC reversed stationary phase for aztreonam and precursors. Aztreonam is a monobactam antibiotic used primarily to treat gram-negative bacterial infections. Group: Pharmaceutical. CAS No. 102579-57-7. Pack Sizes: 10 mg. Product ID: B2694-467194. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azulene | Azulene is used in the preparation of dyes. Group: Pharmaceutical. CAS No. 275-51-4. Pack Sizes: 1 g. Product ID: B0052-293193. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azvudine | Azvudine is a nucleoside reverse transcriptase inhibitor (NRTI), which exhibits inhibtory effects on HIV, HBV and HCV. Group: Pharmaceutical. CAS No. 1011529-10-4. Pack Sizes: 5 mg. Product ID: B2693-338891. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baccatin IX | Baccatin IX is extracted from the leaves and twigs of Taxus yunnanensis. Group: Pharmaceutical. CAS No. 1623410-12-7. Pack Sizes: 1 mg. Product ID: NP1603. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baccatin VIII | Baccatin VIII is extracted from the leaves and twigs of Taxus yunnanensis. It inhibits MCF-7 and HL-60 with IC50 values of 9.67 and 3.44 uM respectively. Group: Pharmaceutical. CAS No. 1623410-10-5. Pack Sizes: 1 mg. Product ID: NP1612. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bacitracin | Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synth. Uses: Topical preparation. Group: Pharmaceutical. CAS No. 1405-87-4. Pack Sizes: 10 g. Product ID: BBF-05843. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bacitracin A-[d7] | Labelled Bacitracin. Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synth. Group: Pharmaceutical. Pack Sizes: 0.5 mg. Product ID: BLP-003382. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bacitracin Impurities | Bacitracin Impurities are integral to the meticulous quality control and rigorous pharmacological evaluation of bacitracin formulations. These impurities facilitate a deeper comprehension of the chemical landscape and assure the safety of bacitracin, an antibiotic pivotal in addressing bacterial infections, including those with resistance to alternative therapeutic agents. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baclofen | Baclofen, an agonist of GABAB receptor, could be effective as a skeletal muscle relaxant and has been also found to have antispastic effect. Uses: Baclofen could be effective as a skeletal muscle relaxant and has been also found to have antispastic effect. Group: Pharmaceutical. CAS No. 1134-47-0. Pack Sizes: 25 g. Product ID: NP3355. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baclofen Impurities | Baclofen Impurities are critical in the pharmaceutical industry for quality control in Baclofen formulations. Their identification and quantification are essential for ensuring the safety and efficacy of the drug used to treat spasticity associated with multiple sclerosis and spinal cord injuries or diseases. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bacoside A3 | Bacoside A is a mixture of chemical compounds, known as bacosides, isolated from Bacopa monnieri. Bacoside A3 is a triterpenoid saponin first isolated from B. monniera, which acts as a potential anticancer compound. Group: Pharmaceutical. CAS No. 157408-08-7. Pack Sizes: 10 mg. Product ID: NP7049. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bafilomycin A1 | It is produced by the strain of Streptomyces griseus ssp. sulphurus TU 1022 and Str. griseus TU 2437. Bafilomycin A1 is a vacuolar H+-ATPase inhibitor with IC50 of 0.44 nM. It can inhibit the growth of gram-positive bacteria, negative bacteria, fungi, yeast and protozoa, and has the effects of insect killing, nematode killing and immunosuppression. Group: Pharmaceutical. CAS No. 88899-55-2. Pack Sizes: 5 mg. Product ID: BBF-00625. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baicalein | Baicalein (5,6,7-trihydroxyflavone) is a flavone, a type of flavonoid, originally isolated from the roots of Scutellaria baicalensis and Scutellaria lateriflora. Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor. Baicalein is a natural compound and can be used in cosmestics material. Uses: Neuroprotective; anticancer. Group: Pharmaceutical. CAS No. 491-67-8. Pack Sizes: 5 g. Product ID: NP1936. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baicalin | Baicalin is a flavone found in several species in the genus Scutellaria, including Scutellaria baicalensis and Scutellaria lateriflora. Baicalin is a positive allosteric modulator of the benzodiazepine site and/or a non-benzodiazepine site of the GABA receptor. Baicalin can also absorb ultraviolet rays, scavenge oxygen free radicals, and inhibit the production of melanin. Therefore, it can be used in medicine and cosmetics. It is a good functional cosmetic raw material. Group: Pharmaceutical. CAS No. 21967-41-9. Pack Sizes: 50 g. Product ID: BBF-03753. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bakkenolide B | Bakkenolide B is isolated from the leaves of Petasites japonicus and exhibits anti-allergic and anti-inflammatory effects. Group: Pharmaceutical. CAS No. 18455-98-6. Pack Sizes: 1 mg. Product ID: NP5640. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bakuchiol | Bakuchiol is a phytoestrogen isolated from the seeds of Psoralea corylifolia L with anti-tumor, antioxidant, and antibacterial effects. Bakuchiol has a retinol-like effect on skin gene expression and properties. Bakuchiol inhibits DNA polymerase and UDP-glucuronosyltransferase 2B7 (IC50 = 41 μM). Bakuchiol has hypoglycemic, hypolipidemic, anti-inflammatory, anti-wrinkle, soothing and liver protective, anticancer, antidepressant, and estrogen-like effects. Uses: Antioxidant. Group: Pharmaceutical. CAS No. 10309-37-2. Pack Sizes: 100 mg. Product ID: NP4619. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Balanol Impurities | Balanol Impurities, integral to pharmaceutical R&D, are paramount for elucidating enzyme inhibitor characteristics. These secondary compounds illuminate kinase modulation, essential for innovating oncology and metabolic disorder therapies. Their meticulous analysis enhances drug formulation refinement, ensuring robust pharmacological efficacy, and advancing therapeutic precision. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (+)-Balanophonin | (+)-Balanophonin is a lignan isolated from the barks of Gmelina arborea and the seeds of Crataegus pinnatifida. Study indicates that (+)-Balanophonin inhibits the proliferation of OPM2 and RPMI-8226 cells. Group: Pharmaceutical. CAS No. 215319-47-4. Pack Sizes: 5 mg. Product ID: B0005-053978. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Balofloxacin Impurities | Balofloxacin Impurities hold paramount importance in the biomedical realm as reference standards for evaluating quality during Balofloxacin drug synthesis. Their analysis is crucial for affirming the safety and efficacy of Balofloxacin, a fluoroquinolone antibiotic, pivotal in managing bacterial infections such as urinary and respiratory tract infections. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baloxavir | Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration. Group: Pharmaceutical. CAS No. 1985605-59-1. Pack Sizes: 50 mg. Product ID: B2692-008721. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baloxavir-[d4] | Baloxavir-[d4] is an isotope compound of Baloxavir. Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration. Group: Pharmaceutical. CAS No. 2415027-80-2. Pack Sizes: 2 mg. Product ID: BLP-003387. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baloxavir marboxil | Baloxavir marboxil is a first-in-class, one-dose oral medicine with a novel proposed mechanism of action that has demonstrated efficacy in a wide range of influenza viruses, including in vitro activity against oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies. Baloxavir is a polymerase acidic, cap-dependent, endonuclease inhibitor that is indicated for the treatment of acute uncomplicated influenza in patients aged 12 years and older who have been symptomatic for no more than 48 hours. It blocks viral proliferation by binding to one of two endonuclease binding sites, inhibiting the initiation of mRNA synthesis for both influenza A and influenza B strains. Baloxavir can interact with polyvalent cation-containing products, which can decrease its plasma concentration. Group: Pharmaceutical. CAS No. 1985606-14-1. Pack Sizes: 50 mg. Product ID: B2692-291710. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baloxavir Marboxil Impurities | Baloxavir Marboxil Impurities, acting as pivotal components within the pharmaceutical development realm, anchor quality assurance protocols for antiviral influenza treatments. These impurities are instrumental in certifying the efficacy and safety profiles of baloxavir marboxil, a leading antiviral agent against influenza, thereby fortifying therapeutic dependability. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Balsalazide Impurities | Balsalazide Impurities occupy a crucial niche within analytical and quality assessment spheres of balsalazide preparations. These constituents are vital for affirming therapeutic integrity and efficacy of balsalazide, principally employed in ulcerative colitis therapy. They enable precise delivery of anti-inflammatory 5-aminosalicylic acid to the colon, thereby mitigating inflammation and fostering remission. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BAM 15 | BAM 15 is a novel mitochondrial protonophore uncoupler that uncouples oxidative phosphorylation in L6 myoblast mitochondria in vitro (EC50 = 270 nM). BAM 15 cannot depolarize the plasma membrane, and protects mice from acute renal ischemic-reperfusion injury. BAM 15 has the potential to treat obesity, Parkinson's disease, and aging. Group: Pharmaceutical. CAS No. 210302-17-3. Pack Sizes: 100 mg. Product ID: B1370-119162. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bamifylline Impurities | Bamifylline Impurities, essential in the pharmaceutics landscape, are pivotal for the meticulous quality control of bamifyllinea bronchodilator utilized in asthma and COPD management. Through enabling the assurance of safety and formulation efficacy, these contaminants underpin consistent therapeutic outcomes and adherence to stringent regulatory standards. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baohuoside II | IKarisoside A is a natural compound isolated from Epimedium koreanum, which has anti-inflammatory properties. Uses: Cardioprotective effect. Group: Pharmaceutical. CAS No. 55395-07-8. Pack Sizes: 5 mg. Product ID: NP1956. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baohuoside V | Baohuoside V is extracted from the herbs of Epimedium brevicornum Maxim. Group: Pharmaceutical. CAS No. 118544-18-6. Pack Sizes: 5 mg. Product ID: B0005-465723. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baohuoside VII | Baohuoside VII is a compound of the flavonoid class found in the herbs of Epimedium brevicornum Maxim. Group: Pharmaceutical. CAS No. 119730-89-1. Pack Sizes: 5 mg. Product ID: B0005-053790. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BAR-501 | BAR-501, a UDCA derivative, is a selective GPBAR1 agonist devoid of any FXR agonistic activity. BAR-501 effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1, with a EC50 of 1 μM. Besides, it protects against development of portal hypertension in rodent models of liver injury and endothelial dysfunction. Group: Pharmaceutical. CAS No. 1632118-69-4. Pack Sizes: 10 mg. Product ID: B0084-482211. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bar-501 Impurities | Bar-501 Impurities hold critical importance within the pharmaceutical realm, particularly in the stringent quality control processes during Bar-501 synthesisa bile acid derivative employed in liver disease management. Vigilant monitoring of these impurities guarantees drug efficacy and safety, essential for addressing chronic hepatic conditions and advancing therapeutic innovations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BAR502 | BAR502 is a dual FXR and GPBAR1 agonist (IC50= 2 μM and 0.4 μM for FXR and GPBAR1, respectively). Group: Pharmaceutical. CAS No. 1612191-86-2. Pack Sizes: 5 mg. Product ID: B0084-007371. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bardoxolone | Bardoxolone is a synthetic oleanane triterpenoid that exerts multifunctional activities in the control of cellular growth and differentiation. Bardoxolone is capable of activating the transcription factor peroxisome proliferator activator receptor-γ (PPARγ), its apoptotic effects in malignant cells have been shown to occur independently of PPAR&gamma. Bardoxolone was developed as an potential drug for the improvement of hyperglycemia, proteinuria, glomerulus structure, serum creatine, which may in turn be beneficial to treat diabetic kidney diseases, cancer and thromboembolic events. Group: Pharmaceutical. CAS No. 218600-44-3. Pack Sizes: 25 mg. Product ID: B0084-427947. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bardoxolone methyl | Bardoxolone methyl (also known as "RTA 402" and "CDDO-methyl ester") is an orally-available first-in-class synthetic triterpenoid belonging to the antioxidant inflammation modulator (AIM) class. It is the most potent known inducer of the Nrf2 pathway to enter clinical development and works to suppress both oxidative stress and inflammation. Uses: bardoxolone methyl, also known as rta 402, is a semisynthetic derivative of oleanolic acid that has attracted much attention in the medical community for its potential to treat a variety of chronic diseases, especially chronic kidney disease (ckd). as a member of the antioxidant inflammatory modulator (aim) class of drugs, bardoxolone methyl exerts its therapeutic effects by targeting inflammat. Group: Pharmaceutical. CAS No. 218600-53-4. Pack Sizes: 250 mg. Product ID: BAT-008967. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baricitinib | Baricitinib is a selective and orally bioactive inhibitor of JAK1 and JAK2. It has been approved by FDA for the treatment of rheumatoid arthritis (RA). Uses: The treatment of rheumatoid arthritis (ra). Group: Pharmaceutical. CAS No. 1187594-09-7. Pack Sizes: 1 g. Product ID: B0084-457382. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Baricitinib phosphate | Baricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1/JAK2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK2 (5.7 nM). Baricitinib has been approved by FDA for the treatment of rheumatoid arthritis (RA). Group: Pharmaceutical. CAS No. 1187595-84-1. Pack Sizes: 25 g. Product ID: B1370-463116. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Barnidipine-[d5] | Barnidipine-[d5] is a stable isotope form of Barnidipine which is a calcium channel blocker. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: BLP-003392. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Barnidipine Impurities | Barnidipine Impurities are critical in the quality control and pharmaceutical analysis of barnidipine, a calcium channel blocker for hypertension management. Identifying and characterizing these impurities ensure the drug's safety, efficacy, and compliance with regulatory standards. Their study aids in understanding the stability and purity of barnidipine formulations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Basmisanil | Basmisanil is a highly selective inverse agonist/negative allosteric modulator GABAAα5 receptors. It was developed by Roche to treat cognitive impairment associated with Down syndrome. In Apr 2016, Roche completed the phase II in Down syndrome (In adolescents, In adults) in USA, Argentina, Canada, France, Italy, Mexico, New Zealand, Singapore, Spain and the UK. In Sep 2016, Phase-II clinical trials in Neurological disorders (In adults, In the elderly) in Spain was on going. Uses: Down syndrome; neurological disorders. Group: Pharmaceutical. CAS No. 1159600-41-5. Pack Sizes: 100 mg. Product ID: B2693-475111. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Batabulin sodium | Batabulin sodium is a synthetic pentafluorophenylsulfonamide with potential antineoplastic activity. T138067 covalently binds to and selectively modifies the beta 1, beta 2, beta 3, and beta 4 isotypes of beta tubulin at a conserved cysteine residue, resulting in disruption of microtubule polymerization, collapse of the cytoskeleton. Group: Pharmaceutical. CAS No. 195533-53-0. Pack Sizes: 50 mg. Product ID: B2693-305409. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Batefenterol | Batefenterol is a Beta 2 adrenergic receptor agonist and also a Muscarinic receptor antagonist. It shows high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic receptors (Ki = 1.3 nM) and hβ2-adrenoceptors (Ki = 3.7 nM). Batefenterol is a hβ2-adrenoceptor agonist with EC50 value of 0.29 nM for stimulation of cAMP levels. This is 440- and 320-fold functional selectivity over hβ1- and hβ3-adrenoceptors. In Jul 2016, GlaxoSmithKline completed a phase II trial for Chronic obstructive pulmonary disease in USA, Germany and South Africa. Uses: Chronic obstructive pulmonary disease. Group: Pharmaceutical. CAS No. 743461-65-6. Pack Sizes: 25 mg. Product ID: B0084-476591. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Batefenterol Succinate | Batefenterol is a beta 2 adrenergic receptor agonist and also a muscarinic receptor antagonist. It shows high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic receptors (Ki = 1.3 nM) and hβ2-adrenoceptors (Ki = 3.7 nM). Batefenterol is a hβ2-adrenoceptor agonist with EC50 value of 0.29 nM for stimulation of cAMP levels. This is 440- and 320-fold functional selectivity over hβ1- and hβ3-adrenoceptors. Group: Pharmaceutical. CAS No. 945905-37-3. Pack Sizes: 25 mg. Product ID: B2693-383251. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Batimastat | Batimastat (also known as BB-94) is a synthetic matrix metalloproteinase inhibitor that has shown antineoplastic and antiangiogenic activity in various tumor models. Batimastat acts as an inhibitor of metalloproteinase activity by binding the zinc ion in the active site of MMPs. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 130370-60-4. Pack Sizes: 10 mg. Product ID: B2693-082981. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bavachin | Bavachin, a natural phytoestrogen found in the fruits of Psoralea corylifolia L, potentially protects cartilage from inflammation-mediated damage in joints of osteoarthritis patients through decreasing IL-1β-induced activation of IKK-IκBα-NF-κB signaling pathway. Bavachin also exhibits the activities of antioxidant, antimutagenic and weak phytoestrogen by binding and activating the estrogen receptor. Group: Pharmaceutical. CAS No. 19879-32-4. Pack Sizes: 50 mg. Product ID: NP1866. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bavachinin | Bavachinin is a natural compound isolated from the Chinese herb Fructus Psoraleae. Bavachinin has potent anti-angiogenic activity in vitro and in vivo. Bavachinin inhibited increases in HIF-1α activity in human KB carcinoma (HeLa cell derivative) and human HOS osteosarcoma cells under hypoxia in a concentration-dependent manner, probably by enhancing the interaction between von Hippel-Lindau (VHL) and HIF-1&alpha. It significantly inhibited Th2 cytokine production, including IL-4, IL-5 and IL-13. Notably, this compound almost completely blocked inflammation in the ovalbumin (OVA)-sensitized animal asthma model. Uses: Antiinflammatory; antipyretic; analgesic. Group: Pharmaceutical. CAS No. 19879-30-2. Pack Sizes: 100 mg. Product ID: NP1951. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BAY-1895344 | BAY-1895344 is a selective ATR (ataxia-telangiectasia and Rad3 related protein) inhibitor that inhibits proliferation of a broad spectrum of human tumor cell lines (median IC50 = 78 nM). BAY-1895344 is developed for the treatment of patients with advanced solid tumors and lymphomas, and it is undergoing a phase I clinical trial of safety and tolerability for cancer patients. Uses: A selective atr (ataxia-telangiectasia and rad3 related protein) inhibitor used for the treatment of advanced solid tumors and lymphomas. Group: Pharmaceutical. CAS No. 1876467-74-1. Pack Sizes: 10 mg. Product ID: B0084-484682. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BAY-218 | BAY-218, which is known as BAY-2335218, is a potent and selective small-molecule AhR inhibitor with an IC50 of 39.9 nM in human cell line. It is a new modality to counteract tumor immunosuppression. Group: Pharmaceutical. CAS No. 2162982-11-6. Pack Sizes: 50 mg. Product ID: B1370-291455. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BAY 299 | BAY 299 is a potent and selective inhibitor of BRD1 and TAF1 (IC50 = 6-67 and 8-13 nM, respectively) with selectivity over other bromodomains (>30-fold over other members of the BRPF family; BRD9 and ATAD2; >300-fold over BRD4). BAY 299 suppresses binding of BRD1 and TAF1 to histone H4 (IC50 = 575 nM and 0.9 μM, respectively) and histone H3.3 (IC50 = 825 nM and 1.4 μM, respectively). Group: Pharmaceutical. CAS No. 2080306-23-4. Pack Sizes: 25 mg. Product ID: B0084-119159. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BAY 41-4109 | BAY 41-4109 is a novel drug inhibiting hepatitis B virus capsid formation and replication. Group: Pharmaceutical. CAS No. 298708-81-3. Pack Sizes: 2 mg. Product ID: B0084-475623. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BAY-57-1293 | BAY 57-1293 represents a new class of potent inhibitors of herpes simplex virus (HSV) that target the virus helicase primase complex. Potent helicase-primase inhibitor (HPI) effective against herpes simplex virus (HSV) infections with IC50 value of 20 nM for inhibition of the replication of both HSV-1 and HSV-2 in Vero cells, and ED50 value of 0.5 mg/kg for both HSV-1 and HSV-2 in the murine lethal challenge model of disseminated herpes. Uses: For research used only. Group: Pharmaceutical. CAS No. 348086-71-5. Pack Sizes: 100 mg. Product ID: B0084-459053. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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