BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Acyclovir L-Isoleucinate | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Group: Pharmaceutical. CAS No. 142963-63-1. Pack Sizes: 5 mg. Product ID: B0093-466140. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Acyclovir L-Leucinate-[d4] | Acyclovir L-Leucinate-[d4] is the labelled analogue of Acyclovir L-Leucinate, which is an amino acid ester of the antiherpetic agent, Acyclovir. It is the Leucine analogue of Valacyclovir. Group: Pharmaceutical. CAS No. 1795785-74-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-013011. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acyclovir Tert-butoxycarbonyl-L-leucinate | Acyclovir Tert-butoxycarbonyl-L-leucinate. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BB061223. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acyclovir triphosphate (triethylammonium salt form) | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Group: Pharmaceutical. CAS No. 186367-53-3. Pack Sizes: 1 mg. Product ID: B0093-007251. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adamantane Impurities | Adamantane Impurities are pivotal in the pharmaceutical industry for ensuring the purity and effectiveness of antiviral drugs, particularly those targeting influenza viruses, like amantadine and rimantadine. By defining contamination benchmarks, these impurities help ascertain drug safety and efficacy, facilitating research innovation in antiviral treatment methodologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adapalene | Adapalene is more active than indomethacin, betamethasone valerate, tretinoin, isotretinoin or etretinate in inhibiting lipoxygease activity, but it has little activity against cyclo-oxygenase. Group: Pharmaceutical. CAS No. 106685-40-9. Pack Sizes: 500 mg. Product ID: B0046-463772. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adapalene EP Impurity B | An impurity of the third-generation topical retinoid Adapalene, which is commonly used to treat skin conditions such as acne and keratosis pilaris. Group: Pharmaceutical. CAS No. 1346599-76-5. Pack Sizes: 5 mg. Product ID: B2694-466163. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adapalene Impurities | Adapalene Impurities hold paramount significance within the biomedical sector, catalyzing quality control and stability evaluations of adapalene formulations, a retinoid targeting acne and dermatological disorders. These impurities facilitate the elucidation of metabolic pathways, underscoring the safety and effectiveness of the drug in skin-related therapeutic applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adefovir dipivoxil | Adefovir Dipivoxil is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV). Uses: Reverse transcriptase inhibitors. Group: Pharmaceutical. CAS No. 142340-99-6. Pack Sizes: 2 g. Product ID: NP3202. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adefovir Dipivoxyl Impurity C | An impurity of Adefovir, a medication used for the treatment of infections with hepatitis B virus. Group: Pharmaceutical. CAS No. 142341-04-6. Pack Sizes: 5 mg. Product ID: B1370-466174. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adefovir Impurities | Adefovir Impurities, essential in the meticulous quality control and analytical examination of adefovir, underpin the antiviral's therapeutic integrity, especially for chronic hepatitis B treatment. These substances are integral in assuring adefovir's safety and efficacy, permitting comprehensive analysis and precise characterization, thus fostering the development of high-purity pharmaceutical solutions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adenanthin | Adenanthin can induce differentiation of acute promyelocytic leukemia (APL) cells, which is isolated from the leaves of Rabdosia adenantha, it also can serve as what is to our knowledge the first lead natural compound for the development of Prx I -and Prx II - targeted therapeutic agents, which may represent a promising approach to inducing differentiation of APL cells. Uses: Anti-inflammatory, anti-tumour, anti-leukemic. Group: Pharmaceutical. CAS No. 111917-59-0. Pack Sizes: 1 mg. Product ID: NP1359. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adenosine-5'-carboxylic Acid | An intermediate in the synthesis of Adenosine 5'-Monophosphate-5',5''-d2 Disodium Salt. Group: Pharmaceutical. CAS No. 3415-9-6. Pack Sizes: 200 mg. Product ID: B2000-218147. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adenosine 5'-monophosphomorpholidate 4-morpholine-N,N'-dicyclohexylcarboxamidine salt | Adenosine 5'-monophosphomorpholidate 4-morpholine-N,N'-dicyclohexylcarboxamidine salt is an intermediate in the Flavine Adenine Dinucleotide synthesis. Group: Pharmaceutical. CAS No. 24558-92-7. Pack Sizes: 50 mg. Product ID: B2001-111086. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| a-D-Glucose-1,6-diphosphate tetra(cyclohexylammonium) salt hydrate | a-D-Glucose-1,6-diphosphate tetra(cyclohexylammonium) salt hydrate, a widely utilized compound in the biomedical sector, represents an invaluable tool for investigating and comprehending glucose metabolism, particularly as it pertains to the development of maladies such as diabetes. In addition, this compound may prove instrumental in facilitating the synthesis of small molecule medications that target various glucose metabolism pathways, more effectively combating related disorders. Group: Pharmaceutical. CAS No. 71662-13-0. Pack Sizes: 5 mg. Product ID: B2705-225090. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adipamidoxime | Adipamidoxime. Group: Pharmaceutical. CAS No. 15347-78-1. Pack Sizes: 100 mg. Product ID: B0001-206439. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adiphenine Impurities | Adiphenine Impurities are crucial in the biomedical industry for evaluating the purity and efficacy of Adiphenine, a drug employed in managing gastrointestinal disorders like irritable bowel syndrome. Understanding these impurities is imperative for enhancing drug safety and quality control, ensuring better therapeutic outcomes for patients. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AdipoRon | AdipoRon is a novel small-molecule AdipoR agonist, binding to both AdipoR1(Kd=1.8 μM) and AdipoR2(Kd=3.1 μM). Group: Pharmaceutical. CAS No. 924416-43-3. Pack Sizes: 100 mg. Product ID: B0084-463481. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adipotide | Adipotide is a peptide drug candidate under clinical trials for the treatment of obesity. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: BAT-006252. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ADPM06 | ADPM06 is a nonporphyrin photodynamic therapeutic (PDT) agent, which is an established treatment modality for cancer. It exhibits IC50s in the micro-molar range in human tumor cells and induces apoptosis. Group: Pharmaceutical. CAS No. 490035-90-0. Pack Sizes: 5 mg. Product ID: B2693-462646. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adrafinil Impurities | Adrafinil Impurities play a critical role in the pharmaceutical industry by ensuring the safety and efficacy of the drug adrafinil, which is used to treat sleep disorders such as narcolepsy. These impurities are meticulously analyzed to uphold rigorous quality standards, thereby aiding in the development of safer and more effective therapeutic agents. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adrenalone Impurities | Adrenalone Impurities occupy a pivotal niche in the biomedical domain, serving as essential tools for probing adrenergic receptor dynamics and advancing cardiovascular treatment development. These impurities facilitate the refinement of adrenergic drug synthesis, crucial for addressing hypertension, cardiac arrest, and COPD, thus elevating drug safety and therapeutic effectiveness. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adrenochrome Impurities | Adrenochrome Impurities, minute by-products derived from adrenaline oxidation, hold considerable significance in biomedical research. They assist in exploring oxidative stress and neurodegenerative disease pathways, illuminating intricate biochemical processes related to disorders like Alzheimer's and Parkinson's, with potential to innovate therapeutic strategies and enhance comprehension of neurological maladies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adrenorphin | Adrenorphin is an opioid octapeptide that acts as an agonist of μ-opioid receptor. Group: Pharmaceutical. CAS No. 88377-68-8. Pack Sizes: 10 mg. Product ID: BAT-006174. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Adrogolide Impurities | Adrogolide Impurities are critical in pharmaceutical research, especially for assessing the purity and safety of dopaminergic drugs used in treating Parkinson's disease. These impurities help in understanding the pharmacokinetics and potential side effects of Adrogolide, thereby guiding the development of safer and more effective therapeutic agents. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ADT-OH | ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. ADT is a putative neuroprotectant and antioxidant that increases glutathione levels in cultured astroglial cells. ADT-OH was shown to reduce tPA-enhanced Akt activation and VEGF expression in brain microvascular endothelial cells. Group: Pharmaceutical. CAS No. 18274-81-2. Pack Sizes: 50 mg. Product ID: B0084-284826. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AEBSF HCl | AEBSF is a water-soluble, irreversible serine protease inhibitor that inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. Group: Pharmaceutical. CAS No. 30827-99-7. Pack Sizes: 1 g. Product ID: B2693-369679. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AEE-788 | AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2), resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor-associated endothelial cell apoptosis. Group: Pharmaceutical. CAS No. 497839-62-0. Pack Sizes: 10 mg. Product ID: B0084-258485. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AEEA-AEEA | 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic acid is a complex organic molecule characterized by multiple functional groups and heteroatoms within its structure. It contains an amino group (-NH2) at the 17th position, a ketone group (oxo) at the 10th position, and several ether linkages (tetraoxa) throughout its carbon chain. Additionally, it features an amide linkage (aza) at the 9th position, which integrates nitrogen into the backbone. This compound is significant in biochemical and pharmaceutical research due to its potential applications in the design and synthesis of novel molecules with specific biological activities. Group: Pharmaceutical. CAS No. 1143516-05-5. Pack Sizes: 1 g. Product ID: BAT-016487. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aegeline Impurities | Aegeline Impurities are component entities within Aegeline-derived compounds, mainly used in pharmaceutical research to evaluate the quality and efficacy of synthesized drugs. These impurities are crucial for ensuring drug safety and efficacy, particularly in treatments targeting metabolic disorders such as obesity and diabetes-related complications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AF 353 | AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. It is a highly potent inhibitor of α,β-meATP-evoked intracellular calcium flux in cell lines expressing recombinant rat and human P2X3 and human P2X2/3 channels. It also blocks human P2X2/3 channel function with marginally reduced potency (pIC50 = 7.3). It significantly reduces this parameter in both groups. It also reduces the inter-contractile interval in control but not in SCI rats. Group: Pharmaceutical. CAS No. 865305-30-2. Pack Sizes: 25 mg. Product ID: B2693-459983. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AF38469 | AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor and shows no activity against the NTR1 receptor. Group: Pharmaceutical. CAS No. 1531634-31-7. Pack Sizes: 100 mg. Product ID: B2693-474607. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afacifenacin Impurities | Afacifenacin Impurities hold paramount importance in the biomedical sphere, serving as keystones for quality assurance in afacifenacin development. These elements meticulously evaluate purity, safety, and effectiveness, underpinning the therapeutic crafting of a muscarinic receptor antagonist crucial for managing overactive bladder syndrome, thereby optimizing patient outcomes through rigorous assessment. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib | Afatinib irreversibly inhibits EGFR/HER2 including EGFR, EGFR(L858R), EGFR(L858R/T790M) and HER2. It is 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 850140-72-6. Pack Sizes: 500 mg. Product ID: B0084-258486. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib-[d6] | Afatinib-[d6] is the labelled analogue of Afatinib. Afatinib is a medication approved for the treatment of metastatic non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It acts via inhibiting EGFR and HER2. Group: Pharmaceutical. CAS No. 1313874-96-2. Pack Sizes: 5 mg. Product ID: BLP-011554. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib dimaleate | Afatinib Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively. Group: Pharmaceutical. CAS No. 850140-73-7. Pack Sizes: 500 mg. Product ID: NP3632. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurities | Afatinib Impurities are critical for assessing the quality and safety of afatinib, a tyrosine kinase inhibitor used in treating non-small cell lung cancer. These impurities provide insights into the drug's stability and degradation pathways, ensuring therapeutic efficacy and compliance with rigorous pharmaceutical standards. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity 52 | Afatinib Impurity 52 is an impurity of Afatinib, a drug used to treat non-small cell lung cancer (NSCLC). Group: Pharmaceutical. CAS No. 618061-76-0. Pack Sizes: 100 mg. Product ID: B2699-424124. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity B | An analogue of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. CAS No. 314771-76-1. Pack Sizes: 10 mg. Product ID: B2694-466202. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity C | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. CAS No. 945553-91-3. Pack Sizes: 10 mg. Product ID: B2694-466206. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity D | An analogue of Afatinib, a medication indicated for the treatment of non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. CAS No. 1680184-59-1. Pack Sizes: 5 mg. Product ID: B2694-466207. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity I | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. CAS No. 1637254-93-3. Pack Sizes: 2.5 mg. Product ID: B1370-377782. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afatinib Impurity J | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. CAS No. 1456696-14-2. Pack Sizes: 10 mg. Product ID: B2694-466213. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afimoxifene | Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia. Uses: Estrogen antagonists. Group: Pharmaceutical. CAS No. 68392-35-8. Pack Sizes: 100 mg. Product ID: B1370-351000. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aflatoxin Impurities | Aflatoxin Impurities hold a crucial place in biomedical research as they elucidate foodborne contamination and detoxification paradigms. Examination of these impurities aids in setting safety benchmarks and devising targeted interventions for aflatoxin-induced hepatic afflictions like hepatocellular carcinoma, thus refining toxicological prevention and therapeutic methodologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aflavazole | Aflavazole is a metabolite of the sclerotia of Aspergillus flavus. It shows antifeedant activity against the fungivorous beetle Carpophilus hemipterus remarkably. Group: Pharmaceutical. CAS No. 2043963-70-6. Pack Sizes: 1 mg. Product ID: BBF-04465. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| a-[[Fmoc]amino]-1-[alloc]-(aS)-4-piperidinepropanoic Acid | a-[[Fmoc]amino]-1-[alloc]-(aS)-4-piperidinepropanoic Acid. Group: Pharmaceutical. CAS No. 313052-03-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BB064758. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afobazole | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Group: Pharmaceutical. CAS No. 173352-21-1. Pack Sizes: 5 mg. Product ID: B0084-458641. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afobazole hydrochloride | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Group: Pharmaceutical. CAS No. 173352-39-1. Pack Sizes: 100 mg. Product ID: B2693-463567. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afoxolaner | Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations in dogs and puppies. It is administered orally in meat-flavoured tablets, and poisons fleas once they start feeding. It is used either alone or as a combination treatment with milbemycin oxime. Group: Pharmaceutical. CAS No. 1093861-60-9. Pack Sizes: 100 mg. Product ID: B2692-475054. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afzelechin | Afzelechin is isolated from the herbs of Celastrus orbiculatus. Uses: Anti-inflammatory activity. Group: Pharmaceutical. CAS No. 2545-00-8. Pack Sizes: 5 mg. Product ID: NP2474. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afzelechin 3-O-xyloside | Afzelechin 3-O-xyloside is purified from the barks of Cassipourea gerrardii. Group: Pharmaceutical. CAS No. 512781-45-2. Pack Sizes: 1 mg. Product ID: NP2142. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Afzelechin-(4α ?8)-epiafzelechin | Afzelechin-(4α →8)-epiafzelechin is a natural compound isolated from the herbs of Cassia javanica. Group: Pharmaceutical. CAS No. 1383627-30-2. Pack Sizes: 1 mg. Product ID: NP2096. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AG 126 | Tyrphostins are protein tyrosine kinase inhibitors developed to inhibit cell growth through blocking the activity of certain GFRK (growth factor receptor kinases). AG 126 selectively inhibits the phosphorylation of ERK1 and ERK2 at 25-50 μM. It also inhibits the production of TNF-α (tumor necrosis factor-α), attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in animal models. AG 126 is a poor inhibitor of epidermal GFRK with IC50 of 450 μM and platelet-derived GFRK with IC50 > 100 μM. AG 126 may represent a new approach for the therapy of inflammation. Uses: Anti- inflammation. Group: Pharmaceutical. CAS No. 118409-62-4. Pack Sizes: 100 mg. Product ID: B1370-195904. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AG 1406 | AG 1406 is an inhibitor of tyrosine phosphorylation. Group: Pharmaceutical. CAS No. 71308-34-4. Pack Sizes: 25 mg. Product ID: B0084-284859. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AG-1557 | AG-1557 is an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Group: Pharmaceutical. CAS No. 189290-58-2. Pack Sizes: 50 mg. Product ID: B0084-284805. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AG-490 | Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 133550-30-8. Pack Sizes: 25 mg. Product ID: B0084-164022. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AG-879 | AG-879, a tyrphostin compound, is a dual EGFR/HER2 inhibitor that was administered together with androgen withdrawal therapy. It inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40 μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM), and the VEGF receptor FLK1 (IC50 = ~1 μM). Group: Pharmaceutical. CAS No. 148741-30-4. Pack Sizes: 20 mg. Product ID: B0084-195953. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agaric acid | Agaric acid. Group: Pharmaceutical. CAS No. 666-99-9. Pack Sizes: 1 g. Product ID: B1370-031094. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AGK2 | AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM. Group: Pharmaceutical. CAS No. 304896-28-4. Pack Sizes: 100 mg. Product ID: B1370-271992. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aglain C | Aglain C, an organic alkaloid of natural origins, demonstrates anti-tumor activity, thus possessing potential application in diverse cancer treatment modalities. It elicits apoptosis, or cell death, in malignant cells, and exhibits anti-inflammatory properties. To ascertain its therapeutic value comprehensively, additional examination is warranted. Group: Pharmaceutical. CAS No. 177468-85-8. Pack Sizes: 2 mg. Product ID: NP0163. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aglaxiflorin D | Aglaxiflorin D is an alkaloid compound isolated from the leaves of Aglaia abbriviata. Group: Pharmaceutical. CAS No. 269739-78-8. Pack Sizes: 2 mg. Product ID: NP0201. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agmatine sulfate salt | Agmatine sulfate, the sulfate preparation of Agmatine, is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Agmatine displaces clonidine at α2-adrenergic and at imidazoline receptors and produces blockade of the NMDA-receptor associated cation channels. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 2482-00-0. Pack Sizes: 1 kg. Product ID: BAT-008149. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agomelatine | Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Group: Pharmaceutical. CAS No. 138112-76-2. Pack Sizes: 20 g. Product ID: NP3699. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agomelatine-[d3] | Agomelatine-[d3] is the labelled analogue of Agomelatin, which is a melatoninergic agonist and selective 5-HT2C receptor antagonist. It is used as an atypical antidepressant in the treatment of major depressive disorder. Group: Pharmaceutical. CAS No. 1079389-38-0. Pack Sizes: 5 mg. Product ID: BLP-009578. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agomelatine Impurities | Agomelatine Impurities hold critical importance in the biomedical spectrum, instrumental for evaluating the antidepressant Agomelatine's quality and safety metrics. Engaging in stringent analytical and formulation research, these impurities underscore the drug's efficacy in managing major depressive disorders, establishing themselves as essential elements in pharmaceutical quality assurance practices. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agouti-related Protein (AGRP) (25-82), human | Agouti-related protein (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It acts as a melanocortin receptor antagonist that exerts a central inhibitory action on the Hypothalamic-Pituitary-Thyroid (HPT) Axis. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BAT-006143. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agrimol B | Agrimol B, a main active ingredient isolated from Agrimonia pilosa Ledeb, possesses insecticidal activity. Uses: Insecticidal. Group: Pharmaceutical. CAS No. 55576-66-4. Pack Sizes: 10 mg. Product ID: B1370-464670. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agrimoniin | Agrimoniin is a natural compound which can be isolated from hairyvein agrimonia. Group: Pharmaceutical. CAS No. 82203-01-8. Pack Sizes: 5 mg. Product ID: B1370-384810. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Agrimonolide | Agrimonolide isolated from the herb of Agrimonia pilosa Ledeb. Group: Pharmaceutical. CAS No. 21499-24-1. Pack Sizes: 1 mg. Product ID: NP1093. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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