BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Tropisetron Impurities | Tropisetron impurities are crucial in assessing the purity and therapeutic efficacy of tropisetron, a selective serotonin 5-HT3 receptor antagonist used primarily in chemotherapy-induced nausea and vomiting. Detecting these impurities ensures the safety and effectiveness of treatments, facilitating stringent quality control in drug manufacturing and development. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Trospectomycin | Trospectomycin is a novel spectinomycin analog with broad-spectrum antibacterial activity. Group: Pharmaceutical. CAS No. 88669-04-9. Pack Sizes: 5 mg. Product ID: B1370-036983. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trospium Chloride | Trospium chloride is a competitive muscarinic cholinergic receptor antagonist. Uses: Urological agents. Group: Pharmaceutical. CAS No. 10405-02-4. Pack Sizes: 5 g. Product ID: B2693-053465. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trospium Chloride Related Compound B | Trospium Chloride Related Compound B is an impurity of Trospium Chloride, an antispasmodic agent used to treat the symptoms of overactive bladder. Group: Pharmaceutical. CAS No. 63516-30-3. Pack Sizes: 500 mg. Product ID: B2694-096121. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trospium Impurities | Trospium Impurities, found in the production of the antimuscarinic agent Trospium Chloride, are crucial in ensuring the purity and safety of medications used for treating overactive bladder and urinary incontinence. Understanding these impurities aids in refining drug formulations, enhancing efficacy, and minimizing adverse effects in therapeutic applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Troxerutin Impurities | Troxerutin Impurities hold significant importance within the pharmaceutical sphere, underpinning stringent quality assurance and progress in troxerutin-centric therapies. Predominantly utilized in the treatment of chronic venous insufficiency and hemorrhoids, these impurities are vital for assessing therapeutic veracity and formulation robustness, thereby ensuring peak medicinal efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trv-130 racemate HCl | Trv-130 racemate HCl, a G-protein-biased mu-opioid receptor partial agonist, exhibits high selectivity and potency in targeting moderate to severe acute pain. Its favorable clinical profile, boasting fewer adverse effects compared to traditional opioid analgesics, shows promise in improving acute pain management and expanding options in opioid therapy. Ongoing evaluations aim to further establish its potential for optimal patient care. Group: Pharmaceutical. CAS No. 1951441-10-3. Pack Sizes: 100 mg. Product ID: B0001-008674. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TRX-0237 mesylate | TRX-0237 mesylate is a second-generation tau protein aggregation inhibitor applicated for the treatment of AD (Alzheimer's disease) and frontotemporal dementia. TRX-0237 is the purified form of Methylene Blue, an old drug that has being widely used in Africa for the treatment of malaria, methemoglobinemia and other conditions for a long time. TRX-0237 is the stabilized, reduced form of methylthioninium chloride to improve the drug's absorption, bioavailability, and tolerability. TRX-0237 is in Phase I for Parkinson's disease, Phase II for Progressive supranuclear palsy and Phase III for Alzheimer's disease and Dementia. Uses: Parkinson's disease; progressive supranuclear palsy; alzheimer's disease; dementia. Group: Pharmaceutical. CAS No. 1236208-20-0. Pack Sizes: 500 mg. Product ID: B2693-474113. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tryprostatin A | Tryprostatin A is a natural compound isolated from Aspergillus fumigatus and arrests cell cycle progression at the G2/M phase. Group: Pharmaceutical. CAS No. 171864-80-5. Pack Sizes: 1 mg. Product ID: BBF-03425. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trypsin Inhibitor (soybean) | Trypsin Inhibitor (soybean) is a peptide inhibitor of serine proteases that reduces trypsin, as well as plasma kallikrein, thrombin, plasmin, and other serine proteases. Group: Pharmaceutical. CAS No. 9035-81-8. Pack Sizes: 10 g. Product ID: B2693-194378. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tryptamine Impurities | Tryptamine Impurities hold paramount importance in pharmaceutical investigations, particularly in decoding the synthesis and ensuring the quality control of tryptamine-centric medications. These markers are instrumental in crafting therapeutic interventions for neurological ailments such as depression and migraine, thereby safeguarding the precision and effectiveness of serotonin-pathway-targeted drugs. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tryptophan Impurities | Tryptophan Impurities hold paramount importance in confirming the purity and quality of pharmaceutical-grade tryptophan. Vigilant surveillance of these impurities is fundamental in producing tryptophan-based treatments, extensively applied in mood disorder, depression, and metabolic disease therapies, ensuring both safety and therapeutic efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TT-232 | TT 232 is a somatostatin analog that acts as a peptide agonist for sst1/sst4 somatostatin receptors. TT 232 inhibits tyrosine kinase activity in human colon tumor cell lines. TT 232 was shown to suppress proliferation and induce apoptosis in a pancreatic tumor cell line. Group: Pharmaceutical. CAS No. 147159-51-1. Pack Sizes: 20 mg. Product ID: BAT-010841. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tubastatin A | Tubastatin A is selective at all isozymes except HDAC8 and maintains over 1000-fold selectivity against all isoforms excluding HDAC8, where it has approximately 57-fold selectivity. Group: Pharmaceutical. CAS No. 1252003-15-8. Pack Sizes: 200 mg. Product ID: B0084-463385. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tubercidin | Tubercidin is an adenosine analog with antiviral, antitrypanosomal, and antifungal properties. It inhibits DNA/RNA synthesis and other metabolic processes. Uses: 7-deaza-adenosine is an adenosine analog. Group: Pharmaceutical. CAS No. 69-33-0. Pack Sizes: 500 mg. Product ID: BBF-03427. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tubermycin B | A simple phenazine produced by several species of pseudomonas and actinomycetes. It is a weakly active antibacterial compound that plays a role in the biocontrol of plant diseases by several pseudomonas strains. Group: Pharmaceutical. CAS No. 2538-68-3. Pack Sizes: 250 mg. Product ID: BBF-03428. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tuberostemonine | Tuberstemonine, coming from the roots of Stemona japonica, exhibited relatively higher intestinal permeabilities. It acts in part as an open-channel blocker at the crayfish neuromuscular junction. Uses: Anti-inflammatory/anti-bacterial/anti-allergy. Group: Pharmaceutical. CAS No. 6879-1-2. Pack Sizes: 20 mg. Product ID: NP0818. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tubotaiwine | Tubotaiwine is isolated from the herbs of Ervatamia divaricata. It shows selective activity against L. infantum. Uses: Analgesic activity. Group: Pharmaceutical. CAS No. 6711-69-9. Pack Sizes: 1 mg. Product ID: NP0116. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tubuloside A | Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity. Group: Pharmaceutical. CAS No. 112516-05-9. Pack Sizes: 25 mg. Product ID: B2703-465680. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tubulysin A | Tubulysin A is a novel antibiotic, which exhibits anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative activity. Tubulysins show very high cytotoxic activity against in vitro and in in vivo tumor models, especially against resistant tumor cell lines. Many representatives of these natural products are several orders of magnitude more potent than other available chemotherapeutics. Uses: Adcs cytotoxin. Group: Pharmaceutical. CAS No. 205304-86-5. Pack Sizes: 1 mg. Product ID: BBF-03429. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tubulysin M | Tubulysin M is a Tubulysin D analog with potential anti-cancer properties, used as the cytotoxic component in antibody-drug conjugates. Group: Pharmaceutical. CAS No. 936691-46-2. Pack Sizes: 0.1 mg. Product ID: BADC-00360. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tucidinostat | Tucidinostat is a novel inhibitor of HDAC1, 2, 3, and 10 with IC50 values of 95, 160, 67, 78 nM, respectively. It increases the acetylation levels of histone H3 and decreases histone deacetylase (HDAC) activity, inducing apoptosis of cancer cells. Group: Pharmaceutical. CAS No. 1616493-44-7. Pack Sizes: 25 mg. Product ID: B2693-292408. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TUG-770 | TUG-770 displayed excellent physicochemical and in vitro ADME properties, with good aqueous solubility, good chemical stability, low lipophilicity, and decreased plasma protein binding (PPB). TUG-770 furthermore showed excellent stability toward human liver microsomes (HLM), no inhibition of selected CYP-enzymes implicated in drug-drug interactions, no P-glycoprotein (P-gp) inhibition, and good permeability in the Caco-2 cell assay. Examination of TUG-770 in an acute intraperitoneal glucose tolerance test (IPGTT) in normal mice revealed a good dose dependent response with maximal reduction in glucose level reached at 50 mg/kg. The effect of TUG-770 was fully sustained after 29 days of daily oral treatment. Additional evaluation of TUG-770 in rats confirmed a significant glucose lowering effect for the high doses already after 10 min and for all doses after 30 min. Group: Pharmaceutical. CAS No. 1402601-82-4. Pack Sizes: 25 mg. Product ID: B0084-463218. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tulathromycin A | Tulathromycin A is a triamilide antibiotic used for the treatment of bovine and porcine respiratory disease. It exists as an equilibrium mixture of two isomeric forms, Tulathromycin A (90%) and B (10%). Uses: Anti-bacterial agents. Group: Pharmaceutical. CAS No. 217500-96-4. Pack Sizes: 5 g. Product ID: BBF-04301. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tulathromycin Impurities | Tulathromycin Impurities are indispensable in quality assurance and safety assessment within antibiotic synthesis, targeting Tulathromycin, a macrolide antibiotic. Their role is instrumental in deciphering the drugs efficacy and potential toxicological profiles, thereby securing its safe therapeutic application in veterinary respiratory bacterial infections. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tumulosic acid | Tumulosic acid is a triterpenoid found in Daedalea dickinsii and Wolfiporia cocos. It inhibits KLK5 protease activity with IC50 of 14.84 μM. Group: Pharmaceutical. CAS No. 508-24-7. Pack Sizes: 10 mg. Product ID: B2703-379034. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tupichinol A | Tupichinol A is a natural compound isolated from the underground parts of Tupistra chinensis. Group: Pharmaceutical. CAS No. 497142-88-8. Pack Sizes: 1 mg. Product ID: NP2147. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Turofexorate Isopropyl | Turofexorate Isopropyl is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist. Group: Pharmaceutical. CAS No. 629664-81-9. Pack Sizes: 25 mg. Product ID: B0084-221750. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tylosin Impurities | Tylosin Impurities, embodying constituents associated with the macrolide antibiotic tylosin, assume a central role in veterinary pharmacology. Their critical function lies in verifying tylosin's purity and efficacy, propelling therapeutic innovations against resistant bacterial strains in livestock, thus amplifying strategies for enhancing animal health management. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tyr0-C-Type Natriuretic Peptide (32-53) | Tyr0-C-Type Natriuretic Peptide (32-53), a peptide hormone, is a crucial regulator of the body's fluid and electrolyte balance. Studies have demonstrated its therapeutic potential in cardiovascular and renal diseases. It exerts its effects via the Natriuretic Peptide Receptor C, thus signifying it as a potential drug target for future development though much remains unknown about the precise mechanisms of its action. Group: Pharmaceutical. CAS No. 142878-79-3. Pack Sizes: 1 mg. Product ID: BAT-006168. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tyramine Impurities | Tyramine Impurities, as trace by-products in synthesizing tyramine-associated compounds, assume considerable importance in scientific inquiry. Their pertinence lies in neurotransmitter modulation, elucidating conditions such as hypertension and migraines through monoamine oxidase influence, thus emerging as potential strategic tools for neurovascular and cardiovascular therapeutic development. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tyrosine Impurities | Tyrosine Impurities, often evaluated in the biomedical industry, are crucial for ensuring the purity and safety of pharmaceutical formulations containing tyrosine. These impurities are meticulously studied to prevent adverse effects, ensuring efficacy in the treatment of conditions like phenylketonuria and thyroid disorders. Detecting these impurities contributes to developing safer tyrosine-based therapies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Udenafil Impurities | Udenafil Impurities, integral to quality assurance, significantly influence the formulation of udenafil, widely utilized for erectile dysfunction therapy. Through meticulous identification and quantification, these impurities underpin the safety, efficacy, and pharmacokinetic assessments, thereby safeguarding the pharmaceutical integrity and therapeutic validity of the medication in clinical applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-6-azido-6-deoxy-D-Gal | UDP-6-azido-6-deoxy-D-Gal, a nucleotide analog with great potential for studying glycosylation, has been employed in the synthesis of azido-sugars and labeling experiments to scrutinize the capabilities of glycosyltransferases. Its utility extends to probing the contribution of glycosylation in widespread pathological processes such as cancer and inflammation. This product can greatly benefit scientific research by providing precise and versatile tools to better understand glycosylation. Group: Pharmaceutical. CAS No. 868208-96-2. Pack Sizes: 1 mg. Product ID: B2706-383271. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-6-azido-6-deoxy-N-acetyl-D-galactosamine disodium salt | UDP-6-azido-6-deoxy-N-acetyl-D-galactosamine disodium salt is a highly significant substance, serving as an indispensable reactive sugar nucleotide analogue for enzyme-mediated labeling and glycoprotein engineering. This compound intricately interweaves within glycosylation-related processes while facilating researchs for cancer, viral infections and autoimmune disorders. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-425892. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-a-D-galactose | UDP-a-D-galactose is a pivotal nucleotide sugar molecule crucial for biosynthesizing carbohydrates and galactose-containing polysaccharides. Its active involvement in the biosynthesis of glycosphingolipids, the building blocks of cell membranes, makes it indispensable. Any impairment of this molecule might trigger galactosemia and other ailments, accentuating its contribution to cellular homeostasis. Group: Pharmaceutical. CAS No. 2956-16-3. Pack Sizes: 25 mg. Product ID: B2706-178577. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-a-D-Xylose disodium | UDP-a-D-Xylose disodium is a remarkable biomedical compound for the research of specific ailments, displaying its functionality as an invaluable precursor for the intricate biosynthesis of glycoconjugates. By actively participating in the convoluted process of polysaccharide and proteoglycan formation within cellular entities, this indispensable compound assumes a fundamental role in the intricate metabolism of Xylose is a vital monosaccharide. Consequently, this extraordinary product finds extensive application within the realm of scientific investigation and therapeutic drug discovery, primarily focusing on the amelioration of intricacies linked to carbohydrate metabolism and glycosylation disorders. Group: Pharmaceutical. CAS No. 108320-89-4. Pack Sizes: 1 mg. Product ID: B2706-339772. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Udp-beta-L-rhamnose | UDP-beta-L-rhamnose, an indispensable biomolecule extensively employed in the realm of biomedicine, assumes a pivotal stance in the intricate process of L-rhamnose biosynthesis. This saccharide, prevalent among diverse pharmaceutical agents and natural substances, acquires utmost significance in the advancement of therapeutics that aspire to combat bacterial infections, certain cancerous manifestations, and afflictions stemming from inflammation. Group: Pharmaceutical. CAS No. 1955-26-6. Pack Sizes: 1 mg. Product ID: B2706-284512. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-D-glucose disodium salt | UDP-D-glucose disodium salt is a phosphorylated uridine derivative used in nucleotide sugars metabolism as a substrate for the enzyme glucosyltransferases. It is used in the treatment of chronic alcoholism and in characterization of limonoid glucosyltransferase. Group: Pharmaceutical. CAS No. 28053-08-9. Pack Sizes: 1 g. Product ID: B1370-368748. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-D-glucuronide trisodium salt | UDP-D-glucuronide trisodium salt is a crucial compound used for drug metabolism studies. It acts as a donor molecule for the glucuronyl transferase enzyme, which helps in the biotransformation and detoxification of a wide range of drugs and endogenous compounds. This trisodium salt form facilitates stability and solubility, making it suitable for drug discovery and pharmacokinetic studies. Group: Pharmaceutical. CAS No. 63700-19-6. Pack Sizes: 250 mg. Product ID: B2706-146244. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-GalNAz disodium salt | UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor. Group: Pharmaceutical. CAS No. 653600-61-4. Pack Sizes: 10 mg. Product ID: B1370-071303. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-GlcNAz.2Na | UDP-GlcNAz.2Na, a biochemical compound with pivotal importance in the field of glycobiology and metabolic labeling, is a metabolic precursor for the intricate biosynthesis of azide-labeled glycans and glycoconjugates, whilst serving as a critical tool in unraveling the intricacies of glycosylation and glycan-mediated interactions in biological systems. Boasting a manifold of applications, including but not limited to the scrutiny of malignant disorders such as cancer, progressive neurodegenerative diseases as Alzheimer's Disease as well as inflammatory disorders, this molecular compound adds substantive value to multifarious scientific endeavors. Group: Pharmaceutical. CAS No. 1611490-64-2. Pack Sizes: 10 mg. Product ID: B2706-383249. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-N-acetyl-D-galactosamine disodium salt | UDP-N-acetyl-D-galactosamine disodium salt is a nucleotide sugar used by glycosyltransferases to transfer N-acetylgalactosamine residues to substrates. Group: Pharmaceutical. CAS No. 108320-87-2. Pack Sizes: 100 mg. Product ID: B2706-358651. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-xylose | UDP-xylose is a crucial compound acting as a substrate in the biosynthesis of xylose which is a sugar component involved in the glycosylation of several proteins and lipids. This enzymatic process plays an essential role in cell-cell recognition, cell signaling and immune responses. Group: Pharmaceutical. CAS No. 3616-6-6. Pack Sizes: 1 mg. Product ID: B2706-144132. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UK-371804 | UK-371804 is a novel and selective inhibitors of urokinase plasminogen activator (uPA). UK-371804 exhibits excellent enzyme potency (Ki 10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin). Group: Pharmaceutical. CAS No. 256477-09-5. Pack Sizes: 100 mg. Product ID: B0084-475596. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ularitide TFA | Urodilatin is a hormone that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B1370-449812. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ulinastatin | Ulinastatin is an acid-resistant protease inhibitor derived from human urine, acting as a potent anti-inflammatory agent. It was shown to inhibit the activities of a variety of enzymes, including trypsin, chymotrypsin, thrombin, kallikrein, plasmin, elastase, cathepsin, lipase, hyaluronidase, factors IXa, Xa, XIa, and XlIa, and polymorphonuclear leukocyte elastase. Group: Pharmaceutical. CAS No. 80449-31-6. Pack Sizes: 1 g. Product ID: B2693-135299. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ulipristal | Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure. Group: Pharmaceutical. CAS No. 159811-51-5. Pack Sizes: 1 g. Product ID: B2692-264332. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ulipristal Acetate | Ulipristal Acetate is an orally bioactive and selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. It binds to the progesterone receptor (PR) to inhibit PR-mediated gene expression. Uses: Emergency contraception and uterine fibroid. Group: Pharmaceutical. CAS No. 126784-99-4. Pack Sizes: 100 mg. Product ID: B0084-474444. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ulipristal Impurities | Ulipristal Impurities are pivotal in the pharmaceutical sector for the quality control and regulatory assessment of Ulipristal acetate medications. These impurities ensure drug safety and efficacy by identifying potential adverse effects, pertaining mainly to contraceptive and uterine fibroid treatments, thereby optimizing therapeutic outcomes. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ulixertinib | Ulixertinib, also known as VRT752271, is an inhibitor of ERK protein kinase. Group: Pharmaceutical. CAS No. 869886-67-9. Pack Sizes: 500 mg. Product ID: B2693-460061. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Umbralisib | Umbralisib is an orally bioavailable and selective PI3K delta inhibitor that targets delta isoform with nanomolar potency, which is approximately 1000-fold selective over alpha isoform, >30-50 fold over beta isoform and >15-50 fold over gamma isoforms. Umbralisib is developed for lymphoma therapy. Group: Pharmaceutical. CAS No. 1532533-67-7. Pack Sizes: 1 g. Product ID: B0084-474608. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Umeclidinium bromide | Umeclidinium bromide(GSK573719A) is a muscarinic receptor antagonist which is useful in treatment of chronic obstructive pulmonary disease (COPD). Group: Pharmaceutical. CAS No. 869113-09-7. Pack Sizes: 25 mg. Product ID: B0084-460044. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UNC-0638 | UNC0638 is an inhibitor of G9a and GLP with excellent potency and selectivity over a wide range of epigenetic and non-epigenetic targets. UNC0638 treatment of a variety of cell lines resulted in lower global H3K9me2 levels, equivalent to levels observed for small hairpin RNA knockdown of G9a and GLP with the functional potency of UNC0638 being well separated from its toxicity. UNC0638 markedly reduced the clonogenicity of MCF7 cells, reduced the abundance of H3K9me2 marks at promoters of known G9a-regulated endogenous genes and disproportionately affected several genomic loci encoding microRNAs. Group: Pharmaceutical. CAS No. 1255580-76-7. Pack Sizes: 25 mg. Product ID: B2693-456088. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UNC1215 | UNC1215 is a potent, selective antagonist of L3MBTL3 with cellular activity. UNC1215 has an IC50 of 20 nM and > 100-fold selectivity over 13 HMTs and selected representatives of kinases, ion channels, 7TMs, and other epigenetic proteins. Group: Pharmaceutical. CAS No. 1415800-43-9. Pack Sizes: 300 mg. Product ID: B0084-462614. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UNC-1999 | UNC1999, the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1. UNC1999 was highly selective for EZH2 and EZH1 over a broad range of epigenetic and non-epigenetic targets. UNC1999 was orally bioavailable in mice, making this inhibitor a valuable tool for investigating the role of EZH2 and EZH1 in chronic animal studies. UNC-1999 represents a useful tools for the biomedical community to investigate the role of EZH2 and EZH1 in health and disease. Group: Pharmaceutical. CAS No. 1431612-23-5. Pack Sizes: 25 mg. Product ID: B2693-462615. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UNC-2025 | UNC-2025 is a novel potent and highly orally bioavailable Mer/FLT3 dual inhibitor, capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow. Kinome profiling versus more than 300 kinases in vitro and cellular selectivity assessments demonstrate that UNC-2025 has similar subnanomolar activity against Flt3, an additional important target in acute myelogenous leukemia (AML), with pharmacologically useful selectivity versus other kinases examined. Group: Pharmaceutical. CAS No. 1429881-91-3. Pack Sizes: 100 mg. Product ID: B2693-462616. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UNC-2025 hydrochloride | UNC-2025 hydrochloride is the hydrochloride salt of UNC-2025, which is the Mer/FLT3 dual inhibitor. Group: Pharmaceutical. CAS No. 2070015-17-5. Pack Sizes: 300 mg. Product ID: B0084-053987. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UNC2250 | UNC2250 is a potent and selective Mer Kinase inhibitor. When applied to live cells, UNC2250 inhibited steady-state phosphorylation of endogenous Mer with an IC50 of 9.8 nM and blocked ligand-stimulated activation of a chimeric EGFR-Mer protein. Treatment with UNC2250 also resulted in decreased colony-forming potential in rhabdoid and NSCLC tumor cells. The results provide a rationale for further investigation of UNC2250 for therapeutic application in patients with cancer. Group: Pharmaceutical. CAS No. 1493694-70-4. Pack Sizes: 50 mg. Product ID: B2693-462617. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UNC 3230 | UNC 3230 is a potent and selective PIP5K1C inhibitor (IC50 = 41 nM), displaying selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. UNC 3230 decreases PIP2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro. UNC 3230 exhibits antinociceptive effects in mouse models of chronic pain. Group: Pharmaceutical. CAS No. 1031602-63-7. Pack Sizes: 100 mg. Product ID: B2693-170513. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Uncargenin C | Uncargenin C isolated from the leaves of Turpinia arguta. Group: Pharmaceutical. CAS No. 152243-70-4. Pack Sizes: 1 mg. Product ID: NP6757. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Uncarine A | Uncarine A is an alkaloid isolated from the leaves of Uncaria hirsuta. Group: Pharmaceutical. CAS No. 6899-73-6. Pack Sizes: 1 mg. Product ID: NP0849. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Uncinatone | Uncinatone is a natural diterpenoid found in the roots of Clerodendrum bungei Steud. Uncinatone shows inhibition of lipopolysaccharide-induced nitric oxide production and inhibitory activity against complement system. Group: Pharmaceutical. CAS No. 99624-92-7. Pack Sizes: 5 mg. Product ID: NP6610. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Uniconazole | Uniconazole is a plant growth hormone that inhibits cytochrome P450 707As, resulting in a suppression of gibberellin production. Uses: Fungicides, industrial. Group: Pharmaceutical. CAS No. 83657-22-1. Pack Sizes: 25 g. Product ID: B0084-078170. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Upadacitinib | Upadacitinib is a selective JAK inhibitor under the development of AbbVie.ABT-494 is nearly 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. Preliminary evidence suggests that ABT-494 may spare Jak2 and Jak3 dependent signaling compared to tofacitinib. Phase II for the treatment of Atopic dermatitis and Crohn's disease, Phase III for the treatment of Rheumatoid arthritis and Ulcerative colitis was on-going. Uses: Rheumatoid arthritis; ulcerative colitis;atopic dermatitis; crohn's disease. Group: Pharmaceutical. CAS No. 1310726-60-3. Pack Sizes: 5 mg. Product ID: B0084-475295. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Uprosertib | Uprosertib, also known as GSK2141795 and GSK795, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Group: Pharmaceutical. CAS No. 1047634-65-0. Pack Sizes: 25 mg. Product ID: B0084-462537. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Uracil | Uracil is one of the four nucleobases in the nucleic acid of RNA, and can be used for drug delivery and as a pharmaceutical. Group: Pharmaceutical. CAS No. 66-22-8. Pack Sizes: 1000 g. Product ID: NP0505. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Urapidil Impurities | Urapidil Impurities are reference standards in pharmaceutical analysis for Urapidil, a medication used primarily to treat hypertension. Understanding these impurities is crucial for assessing drug purity and stability, which are essential for ensuring therapeutic efficacy and safety in medical treatments targeting cardiovascular diseases. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Urazole Impurities | Urazole Impurities play a crucial role in the biomedical industry by contributing to the synthesis of pharmaceuticals aimed at treating cancer and metabolic disorders. These impurities assist in refining therapeutic agents, ensuring their purity and efficacy, thereby enhancing the development of safe and effective drugs. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Urea Impurities | Urea Impurities are significant in the biomedical industry for identifying and controlling quality in pharmaceutical formulations. Their analysis is crucial for monitoring drug purity and stability, particularly in medications for chronic conditions like hypertension and renal failure. Effective management of Urea Impurities enhances the safety and efficacy of these treatments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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