BOC Sciences - Products
London
BOC Sciences provides various research (bio)chemicals: inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities, metabolites, APIs, natural compounds, ADCs, and chiral compounds.
| Product | Description | |
|---|---|---|
| Topotecan hydrochloride | Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Topoisomerase i inhibitors. Group: Pharmaceutical. CAS No. 119413-54-6. Pack Sizes: 1 g. Product ID: NP0530. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Topotecan Impurities | Topotecan Impurities are integral in the pharmaceutical research of antineoplastic agents, vital to developing topotecan, a chemotherapeutic drug used for treating ovarian and small cell lung cancers. Their presence aids in studying drug safety, efficacy, and formulation, ensuring the production of effective cancer treatment options. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Torachrysone | Torachrysone is a natural phenol isolated from the seeds of Cassia obtusifolia. Group: Pharmaceutical. CAS No. 22649-04-3. Pack Sizes: 1 mg. Product ID: NP4642. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Torachrysone 8-O-glucoside | Torachrysone 8-O-glucoside is a natural compound found in the rhizoma of Rheum officinale L. For its inhibitory activities of alpha-glucosidase, it may be used for the treatment of type 2 diabetes. Uses: Anti-diabetes. Group: Pharmaceutical. CAS No. 64032-49-1. Pack Sizes: 10 mg. Product ID: NP5145. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Torcetrapib Impurities | Torcetrapib Impurities, integral to the biomedical realm, are critical in evaluating the safety and therapeutic efficiency of the torcetrapib drug candidate, designed to augment HDL cholesterol levels. The meticulous examination of these impurities ensures drug purity and stability, thereby propelling advancements in cardiovascular disease treatment methodologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Toremifene Impurities | Toremifene Impurities are critical analytical elements within the biomedical landscape, pivotal for ascertaining the purity of toremifene, a vital breast cancer therapeutic agent. These compounds facilitate rigorous quality control, safeguarding toremifene's efficacy and safety in clinical use, further underpinning drug development and manufacturing protocols. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Torin 2 | Torin 2 is a potent and selective mTOR inhibitor with IC50 of 2.1 nM. It inhibits ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM, in PC3 cell lines respectively. It is potentially used as an antineoplastic agent. Group: Pharmaceutical. CAS No. 1223001-51-1. Pack Sizes: 100 mg. Product ID: B0084-272426. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tormentic acid | Tormentic acid is a terpenoid isolated from the herb of Potentilla tormentilla. It inhibits LPS-induced iNOS, COX-2, and TNF-α expression through inactivation of the nuclear factor-κb pathway in RAW 264.7 macrophages. Group: Pharmaceutical. CAS No. 13850-16-3. Pack Sizes: 2 mg. Product ID: NP6588. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Torsemide Impurities | Torsemide Impurities occupy a critical role in assessing Torsemide's diuretic efficacy, safety, and potency, crucial for hypertension and edema management linked with heart and renal ailments. These impurities are essential in ensuring the drug's superior quality via stringent quality control protocols, thereby safeguarding therapeutic reliability and clinical outcomes. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tosedostat | Tosedostat is an aminopeptidase inhibitor for LAP, PuSA and Aminopeptidase N with IC50 of 100 nM, 150 nM and 220 nM, respectively, and does not effectively inhibit either PILSAP, MetAP-2, LTA4 hydrolase, or MetAP-2 with IC50 values are > 1000, > 5000, > 10000 and > 30000 nM for aminopeptidase B, PILSAP, LTA4 hydrolase and MetAP2 respectively. Phase 2. Tosedostat potently inhibits tumor cell proliferation in a variety of tumor cell lines in vitro and in vivo. Group: Pharmaceutical. CAS No. 238750-77-1. Pack Sizes: 100 mg. Product ID: B0084-088218. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tosylglycolic Acid | Tosylglycolic Acid is an intermediate of Cefmetazole. Group: Pharmaceutical. CAS No. 39794-77-9. Pack Sizes: 1 g. Product ID: B2692-121911. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Toyocamycin | Toyocamycin is a pyrrolopyrimidine nucleoside isolated from streptomyces toyocaensis, and also an adenosine nucleotide antimetabolite. It has a broad spectrum of action against bacteria, fungi, protozoans and mammalian cell lines. Uses: Antimetabolites, antineoplastic. Group: Pharmaceutical. CAS No. 606-58-6. Pack Sizes: 100 mg. Product ID: BBF-03421. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tozasertib | The Aurora kinases (A, B, and C) are a family of serine-threonine kinases that regulate various stages of mitotic function. With significant roles in cell cycle and cell division, Aurora kinase gene amplification and overexpression are linked to tumorigenesis. MK 0457 is a potent pan-Aurora kinase inhibitor but favors Aurora A (Ki = 0.6 nM) over Aurora B (Ki = 18 nM) or Aurora C (Ki = 4.6 nM). It shows selectivity against a panel of more than 190 different protein kinases. MK 0457 effectively inhibits proliferation of several different cell lines of clear cell renal carcinoma (IC50s < 10 μM) and blocks the growth of tumors in a rodent model of cancer (80 mg/kg), inhibiting histone H3 phosphorylation and increasing apoptosis. By depleting Aurora activity, MK 0457 disrupts bipolar spindle formation during mitosis, arresting cell cycle progression at the G2/M phase. Group: Pharmaceutical. CAS No. 639089-54-6. Pack Sizes: 250 mg. Product ID: B0084-074159. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TP 064 | TP 064 is a potent and selective PRMT4 inhibitor with >100-fold selectivity over other histone methyltransferases and non-epigenetic targets. TP 064 inhibits methylation of H3 (1-25) and MED12 in cellular assays (IC50 values are <10 and 43 nM, respectively). Group: Pharmaceutical. CAS No. 2080306-20-1. Pack Sizes: 25 mg. Product ID: B2693-170422. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TP-0903 | TP-0903 is a potent anti-cancer agent targeting the AXL receptor tyrosine kinase that has demonstrated profound activity in several cell-based and animal models of cancer. Uses: For research use only. Group: Pharmaceutical. CAS No. 1341200-45-0. Pack Sizes: 100 mg. Product ID: B2693-464265. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TP-10 | TP-10 is a PDE10A inhibitor with IC50 of 0.8 nM. It has extremely potent PDE10A inhibitory activity and high selectivity against other PDEs. It is active in the mouse behavioral model for positive symptoms. It demonstrats good in vitro and in vivo activity. Group: Pharmaceutical. CAS No. 898563-00-3. Pack Sizes: 10 mg. Product ID: B0084-460312. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TPCA-1 | TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM and 0.40 μM for IKK-1 and IKK-2 respectively. It blocks NF-κB pathway and STAT3 activity. Group: Pharmaceutical. CAS No. 507475-17-4. Pack Sizes: 200 mg. Product ID: B0084-272427. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TPT-260 2HCl | TPT-260 2HCl is a thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation. Group: Pharmaceutical. CAS No. 2076-91-7. Pack Sizes: 25 mg. Product ID: B0084-462304. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TR-14035 | TR14035 blocked the binding of human alpha(4)beta(7) to an (125)I-MAdCAM-Ig fusion protein with IC(50) values of 0.75 nM. TR14035 blocked binding of human alpha(4)beta(7)-expressing RPMI-8866 cells or murine mesenteric lymph node lymphocytes to MAdCAM-Ig with IC(50) values of 0.1 microM. TR14035 blocked adhesion to HEVs [ED(50) of 0.01-0.1 mpk i.v.]. TR-14035 was taken up by rat and human hepatocytes by an apparently single saturable mechanism with K(m) of 6.7 and 2.1 microM, respectively, and taurocholate and digoxin reduced this uptake. Group: Pharmaceutical. CAS No. 232271-19-1. Pack Sizes: 5 mg. Product ID: B0084-463603. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trabectedin | Trabectedin is an antitumor drug. Group: Pharmaceutical. CAS No. 114899-77-3. Pack Sizes: 10 mg. Product ID: B0046-465349. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trachelosiaside | Trachelosiaside is isolated from the leaves of Trachelospermum lucidum (D. Don) Schum. Trachelosiaside shows moderate activity against lipoxygenase. Group: Pharmaceutical. CAS No. 106647-12-5. Pack Sizes: 1 mg. Product ID: NP4131. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trametinib | A MEK inhibitor that suppresses MEK1 and MEK2 with IC50 of 0.92 and 1.8 nM and no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. It has been approved by FDA, in combination with Tafilnar, for the treatment of metastatic anaplastic thyroid cancer (ATC) with BRAF V600E mutation. Group: Pharmaceutical. CAS No. 871700-17-3. Pack Sizes: 500 mg. Product ID: B0084-307744. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trametinib impurities | Trametinib impurities, arising during the synthesis of the melanoma therapeutic Trametinib, are vital for validating the compound's purity and therapeutic effectiveness. By ensuring rigorous assessment of these by-products, their influence on MEK1 and MEK2 protein inhibition, essential in halting cancer proliferation, is meticulously maintained, safeguarding treatment integrity. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trandolapril | Trandolapril is an angiotensin converting enzyme (ACE) inhibitor. It has a longer biological half-life and a high degree of lipophilicity than others. It is used to treat high blood pressure. It acts by competitive inhibition of ACE, which is a key enzyme in the renin-angiotensin system and plays an important role in regulating blood pressure. lt inhibits atherosclerosis1 and decreases the occurrence of atrial fibrillation2. It is marketed by Abbott Laboratories under the brand name Mavik. It has been listed. Uses: Trandolapril is used to treat high blood pressure. Group: Pharmaceutical. CAS No. 87679-37-6. Pack Sizes: 500 mg. Product ID: BAT-010063. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trandolapril Impurities | Trandolapril Impurities, crucial in the pharmaceutical industry, are monitored and analyzed to ensure the safety and efficacy of the antihypertensive drug Trandolapril. These impurities aid in understanding the drug's stability, degradation pathways, and potential side effects, thus supporting the development of effective treatments for hypertension and related cardiovascular diseases. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-1-Amino-4-(hydroxymethyl)cyclohexane | Metabolites of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (Me CCNU). Group: Pharmaceutical. CAS No. 1467-84-1. Pack Sizes: 25 g. Product ID: BB010122. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-2-Aminocyclohexanol | trans-2-Aminocyclohexanol (CAS# 6982-39-4) is a useful building block for organic synthesis. Group: Pharmaceutical. CAS No. 6982-39-4. Pack Sizes: 50 g. Product ID: BB033985. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-2-Butene-1,4-diol | trans-2-Butene-1,4-diol is an impurity of Gadobutrol, which is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI). Group: Pharmaceutical. CAS No. 821-11-4. Pack Sizes: 10 g. Product ID: B2699-224127. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-2-Methyl-2-pentenoic acid | Trans-2-Methyl-2-pentenoic acid is an unsaturated analog of the anticonvulsant Valproic Acid and is used for aroma characterization of different beers with different hops. Group: Pharmaceutical. CAS No. 16957-70-3. Pack Sizes: 1 kg. Product ID: B1370-304852. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-3-Hexenoyl-CoA sodium salt | trans-3-Hexenoyl-CoA sodium salt is an imperative biochemical compound, exerting a pivotal influence on fatty acid metabolism and participates in myriad biochemical processes. Predominantly employed in investigations and analyses associated with lipid metabolism, this product additionally finds utility in the fabrication of pharmaceuticals aimed at studying metabolic ailments including diabetes and obesity. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-410020. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-4,5-Difluoroethylenecarbonate | trans-4,5-Difluoroethylenecarbonate (CAS# 311810-76-1 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 311810-76-1. Pack Sizes: 50 g. Product ID: B2699-165506. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-4-Butylcyclohexanol | Trans-4-Butylcyclohexanol, a vital compound in pharmaceutical and agrochemical industries, serves as a key intermediate in the synthesis of a wide range of organic compounds, including amides, esters, and ketones. Notably, its ability to serve as a starting material in the preparation of drug substances and biochemicals highlights its paramount importance. Its versatility and functional properties make Trans-4-Butylcyclohexanol an indispensable component in the chemical research of life-changing drugs and biochemical products. Group: Pharmaceutical. CAS No. 67590-13-0. Pack Sizes: 5 g. Product ID: B2699-413990. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-4-Pentylcyclohexanecarboxylic acid | trans-4-Pentylcyclohexanecarboxylic acid is a useful research chemical. Group: Pharmaceutical. CAS No. 38289-29-1. Pack Sizes: 500 g. Product ID: B1370-022446. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-4- (Trifluoromethyl) cyclohexanecarboxylic acid | A cyclic haloalkyl substituted carboxylic acid used in the preparation of antiviral agents. Group: Pharmaceutical. CAS No. 133261-33-3. Pack Sizes: 10 g. Product ID: B2699-300123. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-beta-Farnesene | (E)-β-Farnesene is a naturally volatile sesquiterpene hydrocarbon found in Phlomis aurea Decne essential oil, Nepeta nepetella and Eupatorium capillifolium. It can be used as a feeding stimulant for sandfly Lutzomyia longipalpis. Group: Pharmaceutical. CAS No. 18794-84-8. Pack Sizes: 10 g. Product ID: B2699-365356. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-Clomiphene Citrate | Enclomiphene citrateis a non-steroidal estrogen receptor antagonist. It can be used for secondary hypogonadism in overweight men wishing to restore normal testicular function. Uses: Restore testicular function. Group: Pharmaceutical. CAS No. 7599-79-3. Pack Sizes: 2.5 mg. Product ID: B0084-476606. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Transdermal Peptide | TD-1 binds to Na+/K+-ATPase beta-subunit (ATP1B1) and interacts with the C-terminus of ATP1B1 in yeast and mammalian cells. Group: Pharmaceutical. CAS No. 918629-48-8. Pack Sizes: 5 mg. Product ID: BAT-006224. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-doxercalciferol | Trans-doxercalciferol is an isomer of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Group: Pharmaceutical. CAS No. 74007-20-8. Pack Sizes: 5 mg. Product ID: B1959-261135. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-maxacalcitol | Trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 929721-98-2. Pack Sizes: 1 mg. Product ID: B1128-054098. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-trans-4, 4'-Iminodimethylenedi (cyclohexanecarboxylic acid) | trans-trans-4, 4'-Iminodimethylenedi (cyclohexanecarboxylic acid) (CAS# 93940-19-3 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 93940-19-3. Pack Sizes: 100 mg. Product ID: B2699-274759. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| trans-zeatin | Zeatin, purified from Zea mays, is a member of the cytokinin group of plant growth factors, the activity of which is attributed to its more stable trans form. Group: Pharmaceutical. CAS No. 1637-39-4. Pack Sizes: 5 g. Product ID: B2703-060361. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tranylcypromine hydrochloride | Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and human liver microsomes, respectively. Group: Pharmaceutical. CAS No. 1986-47-6. Pack Sizes: 1 g. Product ID: B0084-462918. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tranylcypromine Impurities | Tranylcypromine Impurities are vital constituents in the realm of pharmaceutical development and quality assessment, particularly for Tranylcypromine's deployment in major depressive disorder therapies. Their analysis enhances comprehension of the compound's stability and safety profile, thereby assuring therapeutic potency and safeguarding patient well-being in clinical environments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TRAP-5 | TRAP-5 is a thrombin receptor activator. Thrombin receptor is a G protein-coupled receptor involved in the regulation of thrombotic response. Group: Pharmaceutical. CAS No. 141685-53-2. Pack Sizes: 10 mg. Product ID: BAT-006219. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trapidil | Trapidil, also called as Rocornal, is a platelet aggregation inhibitor with specific platelet-derived growth factor. Uses: Vasodilator agents. Group: Pharmaceutical. CAS No. 15421-84-8. Pack Sizes: 1 g. Product ID: B2692-059669. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trastuzumab emtansine | Trastuzumab emtansine is an antibody-drug conjugate (ADC) consisting of the recombinant anti-epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab conjugated to the maytansinoid DM1 via a nonreducible thioether linkage (MCC) with potential antineoplastic activity. The trastuzumab moiety of this ADC binds to HER2 on tumor cell surface surfaces. Upon internalization, the DM1 moiety is released and binds to tubulin, thereby disrupting microtubule assembly/disassembly dynamics and inhibiting cell division and the proliferation of cancer cells that overexpress HER2. Linkage of antibody and drug through a nonreducible linker has been reported to contribute to the improved efficacy and reduced toxicity of this ADC compared to similar ADCs constructed with reducible linkers. Group: Pharmaceutical. CAS No. 1018448-65-1. Pack Sizes: 5 mg. Product ID: BADC-00023. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Travoprost | Travoprost is a potent and selective FP prostaglandin receptor agonist used for the treatment of glaucoma. Group: Pharmaceutical. CAS No. 157283-68-6. Pack Sizes: 100 mg. Product ID: B0084-059917. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Travoprost Acid | One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Group: Pharmaceutical. CAS No. 54276-17-4. Pack Sizes: 10 mg. Product ID: B1370-447705. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Travoprost Impurities | Travoprost Impurities, serving as critical analytical constituents, are indispensable in the nuanced exploration of prostaglandin analogs, underpinning rigorous pharmaceutical quality assurance. Their examination is crucial for validating the safety and therapeutic potency of travoprost compositions, essential for managing ocular conditions like glaucoma and ocular hypertension via intraocular pressure reduction. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Traxillaside | Traxillaside is purified from the barks of Torreya nucifera Sieb. et Zucc. It has significant neuroprotective activities against glutamate-induced toxicity in primary cultures of rat cortical cells. Group: Pharmaceutical. CAS No. 149415-62-3. Pack Sizes: 1 mg. Product ID: NP4074. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trazodone Impurities | Trazodone Impurities, crucial for quality control and pharmacological research, help assess the purity and stability of the antidepressant trazodone. These impurities play a pivotal role in ensuring the efficacy and safety of the drug, aiding in the optimization of therapeutic outcomes for depression and anxiety-related disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trazodone Impurity C | One of the impurities of Trazodone, which has been found to be effective as an antidepressant agent. Group: Pharmaceutical. CAS No. 1263278-77-8. Pack Sizes: 50 mg. Product ID: B2694-484397. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trehalose-6,6'-dibehenate | Trehalose-6,6'-dibehenate is a bioactive glycolipid and an analog of mycobacterial cord factor. Trehalose-6,6'-dibehenate is considered less toxic and an efficient vaccine adjuvant for tuberculosis. Group: Pharmaceutical. CAS No. 66758-35-8. Pack Sizes: 25 mg. Product ID: B1370-252651. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trehalulose | Trehalulose, a disaccharide carbohydrate, is a compelling low-calorie sweetener with therapeutic benefits in metabolic disorders such as diabetes. Its mechanism, involving blood glucose level regulation, has shown promising results. Moreover, trehalulose has evidenced antioxidant properties, which could support its potential as a neuroprotective agent against Alzheimer's disease, revealing positive outcomes. Group: Pharmaceutical. CAS No. 51411-23-5. Pack Sizes: 100 mg. Product ID: B1999-143335. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Trelagliptin Impurities | Trelagliptin Impurities, critical in the pharmaceutical industry, are employed to ensure the purity and efficacy of Trelagliptin, a drug used to treat type 2 diabetes. These impurities support rigorous quality control in drug manufacturing, enhancing the therapeutic potential of Trelagliptin by minimizing adverse effects and optimizing patient outcomes. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Treosulfan | Treosulfan is the prodrug of a bifunctional sulfonate alkylating agent with myeloablative, immunosuppresive, and antineoplastic activities. Under physiological conditions, treosulfan converts nonenzymatically to L-diepoxybutane via a monoepoxide intermediate. The monoepoxide intermediate and L-diepoxybutane alkylate DNA at guanine residues and produce DNA interstrand crosslinks, resulting in DNA fragmentation and apoptosis. In escalated doses, this agent also exhbits myeloablative and immunosuppressive activities. Group: Pharmaceutical. CAS No. 299-75-2. Pack Sizes: 25 mg. Product ID: B2693-065470. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Treprostinil | Treprostinil is a vasodilator used for the treatment of pulmonary arterial hypertension. It is a synthetic analog of prostacyclin. Treprostinil is an epoprostenol receptor agonist and platelet aggregation inhibitor. Uses: The treatment of pulmonary arterial hypertension. Group: Pharmaceutical. CAS No. 81846-19-7. Pack Sizes: 10 mg. Product ID: B0084-136086. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Treprostinil-[13C2,d1] | Treprostinil-[13C2,d1] is a labelled analogue of Treprostinil. Treprostinil is an analogue of prostacyclin (PGI2) that is used for the treatment of pulmonary arterial hypertension (PAH). Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-014788. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Treprostinil-[d9] | Treprostinil-[d9] is a labelled form of Treprostinil. Treprostinil is an analogue of prostacyclin (PGI2) that is used for the treatment of pulmonary arterial hypertension (PAH). Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-008163. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Treprostinil Impurities | Treprostinil Impurities hold paramount importance in the realm of quality control and pharmacological exploration concerning treprostinil, a therapeutic agent targeting pulmonary arterial hypertension. These impurities furnish essential reference benchmarks, aiding in the precise identification and quantification of impurities, thereby fortifying the efficacy and safety of treprostinil formulations during drug manufacturing intricacies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tretazicar | Tretazicar (CB1954) is a dinitrobenzamide prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide (EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. CB1954 has been proposed for use in enzyme-prodrug gene therapy systems with the Escherichia coli enzyme nitroreductase (Ntr). Ntr converts CB1954 to 2- and 4-hydroxylamino derivatives, whereupon the non-enzymatic reaction of the 4-hydroxylamino derivative with cellular thio- esters generates a potent cytotoxic bifunctional alkylating agent capable of cross-linking DNA. Ntr delivery has been achieved in vitro using retroviral and adenoviral vectors and confirmed by immunocytochemical demonstration of Ntr expression. The Ntr-expressing cells have been shown to be sensitized to CB1954 by up to 2000-fold. The Ntr-CB1954 system shows effective bystander killing in mixed populations of Ntr-expressing and non-expressing cells treated with CB1954. The efficacy of this enzyme-prodrug approach in model systems compared with other VDEPT approaches demonstrates the feasibility and future promise of this gene therapy strategy. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 21919-05-1. Pack Sizes: 1 g. Product ID: B2693-366889. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tretinoin | Tretinoin, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. Group: Pharmaceutical. CAS No. 302-79-4. Pack Sizes: 5 g. Product ID: B2693-462931. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Triacetylpseurotin A | Triacetylpseurotin A is an alkaloid produced from endophyte of Polygonum cuspidatum. Group: Pharmaceutical. CAS No. 77353-57-2. Pack Sizes: 1 mg. Product ID: NP0751. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Triallat Impurities | Triallat Impurities, recognized as inherent byproducts in agrochemical creation, undergo scrutiny for their implications on human health. Their examination in biomedical research emphasizes assessing the consequences of triazine herbicide exposure on metabolic pathways, steering safety assessments and therapeutic strategies for ailments linked to environmental toxin interactions. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Triamcinolone Impurities | Triamcinolone Impurities, critical in the biomedical arena, are utilized to ensure the purity and efficacy of Triamcinolone-based pharmaceuticals. These impurities are pivotal in quality control and drug safety studies, particularly in treating allergic reactions, arthritis, and dermatological disorders, by assessing potential adverse effects during drug development. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Triamterene Impurities | Triamterene Impurities are leveraged in the biomedical industry to evaluate the purity and efficacy of the diuretic drug Triamterene, used for managing hypertension and edema. The presence of these impurities helps researchers optimize drug synthesis and ensure patient safety by studying metabolic pathways and potential side effects. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Triazole Impurities | Triazole Impurities, integral to the synthesis and scrutiny of antifungal and antimicrobial pharmaceuticals, underpin compounds like fluconazole and itraconazole. These impurities are imperative for quality assurance and structural characterization, thereby safeguarding the therapeutic integrity and safety of triazole-based formulations against fungal and microbial adversaries. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Triazole lactic acid | Triazole lactic acid. Group: Pharmaceutical. CAS No. 1450828-63-3. Pack Sizes: 10 mg. Product ID: B2699-383252. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tribromobisphenol A | Tribromobisphenol A (CAS# 6386-73-8 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 6386-73-8. Pack Sizes: 100 mg. Product ID: B2699-030854. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Tribuloside | Tribuloside is a flavonoid isolated from Tribulus terrestris L with antimycobacterial activity. Group: Pharmaceutical. CAS No. 22153-44-2. Pack Sizes: 20 mg. Product ID: B2703-206357. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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