A directory of where to buy chemicals in the UK including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information.
| Product | Description | |
|---|---|---|
| Avapritinib | BLU-285 is a potent and selective inhibitor of exon 17 mutant KIT (IC50 = 0.27 nM for KIT D816V). BLU-285 showed dose-dependent, robust anti-tumor efficacy in a TKI-resistant KIT exon 11/17 mutant GIST PDX model through inhibition of tumor growth, proliferation, KIT signaling and induction of apoptosis. Group: Pharmaceutical. CAS No. 1703793-34-3. Pack Sizes: 10 mg. Product ID: B0084-007732. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Avatrombopag | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Group: Pharmaceutical. CAS No. 570406-98-3. Pack Sizes: 100 mg. Product ID: B2693-144359. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avatrombopag maleate | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Group: Pharmaceutical. CAS No. 677007-74-8. Pack Sizes: 100 mg. Product ID: B2693-216033. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avenasterol Impurities | Avenasterol Impurities hold paramount importance in biomedical exploration, crucial for elucidating sterol metabolic pathways and diagnosing lipid abnormalities. Their role extends to the synthesis and analysis of hypocholesterolemic agents, thereby making significant contributions to hyperlipidemia treatment advancements and atherosclerosis research breakthroughs. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avibactam Impurities | Avibactam impurities, indispensable for evaluating the purity and safety of Avibactam, a non-β-lactam β-lactamase inhibitor, are paramount when combined with antibiotics such as ceftazidime, targeting formidable infections by resistant bacteria. Thorough comprehension of these impurities enhances formulation effectiveness and mitigates adverse effects during therapeutic applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avibactam Impurity 6 | An impurity of Avibactam, a non-β lactam β-lactamase inhibitor that inactivates some β-lactamases. Group: Pharmaceutical. CAS No. 1192651-49-2. Pack Sizes: 25 mg. Product ID: B2694-467077. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avibactam sodium | 100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C7H10N3O6S ·Na. CAS No. 1192491-61-4. Prepack ID : 90023818-100mg. Molecular Weight : 287.2. |  |
| Avibactam Sodium Salt | Avibactam Sodium Salt, a novel non-?-lactam ?-lactamase inhibitor, binds covalently to Ambler class A ?-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens. Group: Pharmaceutical. CAS No. 1192491-61-4. Pack Sizes: 500 mg. Product ID: B0084-465274. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avicularin | Avicularin, a natural plant flavonoid isolated from the herbs of Polygonum aviculare, exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. By decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase, avicularin can inhibit the accumulation of the intracellular lipids. Uses: Anti-inflammatory. Group: Pharmaceutical. CAS No. 572-30-5. Pack Sizes: 10 mg. Product ID: NP1949. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avicularin Impurities | Avicularin Impurities play crucial roles in the biomedical industry, particularly in the quality control and development of anti-inflammatory and antioxidant treatments. By studying these impurities, researchers enhance the purity and efficacy of avicularin-based pharmacological compounds, which are used in treating conditions like cancer and cardiovascular diseases. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avilamycin Impurities | Avilamycin Impurities hold central importance in the comprehensive analytical evaluation of avilamycin, a veterinary antibiotic targeting Gram-positive bacterial infections in livestock. Their discernment and characterization are pivotal for ensuring avilamycin's safety and effectiveness, while also probing the mechanisms of antibiotic resistance within agricultural systems. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aviptadil | Aviptadil Acetate is an analog of vasoactive intestinal polypeptide (VIP) as Vasoactive intestinal peptide receptor agonists for the treatment of erectile dysfunction. Uses: Vasoactive intestinal peptide receptor agonists. Group: Pharmaceutical. CAS No. 40077-57-4. Pack Sizes: 5 mg. Product ID: BAT-006136. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avitriptan Impurities | Avitriptan Impurities hold a crucial position in the biomedical sphere, pivotal for the advancement and optimization of avitriptan, a drug targeting migraine mitigation. These impurities facilitate researchers' efforts in refining drug purity, effectiveness, and safety, thus fine-tuning therapeutic efficacy for individuals afflicted with migraines. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AVL-292 | AVL-292, also known as CC-292, is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity. Uses: Protein kinase inhibitors. Group: Pharmaceutical. CAS No. 1202757-89-8. Pack Sizes: 1 g. Product ID: B2693-462475. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AVN-492 | AVN-492 is a novel potent and selective 5-HT6 receptor antagonist with Ki values of 91 pM and 170 nM for 5-HT6R and 5-HT2BR, respectively. Uses: Serotonin antagonists. Group: Pharmaceutical. CAS No. 1220646-23-0. Pack Sizes: 200 mg. Product ID: B0084-007690. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avobenzone | Avobenzone. Group: Uv absorbers. Categories: avobenzone; 70356-09-1. |  |
| Avobenzone | Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative. Group: Pharmaceutical. CAS No. 70356-09-1. Pack Sizes: 500 g. Product ID: B2697-347173. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avo Benzone | Avo Benzone. Categories: Avobenzone. | |
| Avocado | Avocado. Group: Organic carrier oils. | |
| AVOCADO STONE | AVOCADO STONE - Our signature range of liquid botanical extracts |  England, Scotland |
| AWD 131-138 | AWD 131-138 is a partial agonist of GABAA receptor with low affinity for the benzodiazepine binding site. AWD 131-138 exhibits potent anticonvulsant and anxiolytic properties in rodent models. It is used as an antiepileptic drug for the treatment of canine idiopathic epilepsy. Group: Pharmaceutical. CAS No. 188116-07-6. Pack Sizes: 10 mg. Product ID: B0084-244924. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Axinysone A | Axinysone A is a natural compound used in the research of cancer. Derived from natural sources, this product acts as a valuable inhibitor of specific signaling pathways involved in tumor growth and progression. Group: Pharmaceutical. CAS No. 1114491-57-4. Pack Sizes: 1 mg. Product ID: NP5852. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Axitinib | Axitinib (AG013736) is a tyrosine kinase inhibitor developed by Pfizer. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Uses: Protein kinase inhibitors. Group: Pharmaceutical. CAS No. 319460-85-0. Pack Sizes: 5 g. Product ID: NP3631. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Axitinib Impurities | Axitinib Impurities hold paramount significance in pharmaceutical scrutiny, profoundly enhancing comprehension of axitinib, an essential tyrosine kinase inhibitor utilized in renal carcinoma treatment. These nuanced elements reveal drug stability, ensuring safety and therapeutic exactitude, thereby advancing cancer agent refinement and potentially elevating oncology treatment paradigms. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Axitinib Impurity 2 | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Group: Pharmaceutical. CAS No. 1428728-83-9. Pack Sizes: 5 mg. Product ID: B2694-467092. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Axitinib sulfoxide | A major metabolite of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Group: Pharmaceutical. CAS No. 1347304-18-0. Pack Sizes: 10 mg. Product ID: B2694-467095. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ayanin | Ayanin isolated from the rhizomes of Curcuma aromatica. Group: Pharmaceutical. CAS No. 572-32-7. Pack Sizes: 1 mg. Product ID: NP2101. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AY-NH2 | AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Group: Pharmaceutical. CAS No. 352017-71-1. Pack Sizes: 5 mg. Product ID: BAT-006106. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZ5104 | AZ5104 is a potent EGFR inhibitor and a derivative of AZD 9291. AZ5104 exhibits reduced selectivity against wild-type EGFR but five-fold potentcy compared to AZD 9291. Group: Pharmaceutical. CAS No. 1421373-98-9. Pack Sizes: 25 mg. Product ID: B0084-470856. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZ7371 | AZ7371 is a novel non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with IC50 of 10 nM. Group: Pharmaceutical. CAS No. 1494675-86-3. Pack Sizes: 50 mg. Product ID: B2693-470868. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZ-960 | AZ-960 is an ATP-competitive inhibitor of JAK2 with Ki value of 0.45 nM. It inhibits proliferation in a SET-2 human megakaryoblastic cell line harboring the JAK2V617F mutation with GI50 value of 33 nM. Group: Pharmaceutical. CAS No. 905586-69-8. Pack Sizes: 50 mg. Product ID: B1370-286345. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azacitidine Impurities | Azacitidine Impurities encompass various byproducts in the synthesis of azacitidine, a chemotherapeutic agent used primarily to treat myelodysplastic syndromes and certain types of leukemia. Identifying and analyzing these impurities is crucial for ensuring the efficacy and safety of azacitidine formulations, thus aiding in effective disease management and regulatory compliance. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azadirachtin B | Azadirachtin B is a drug analog of azadirachtin which was investigated in agrochemical studies of bioregulators for the antifeedant mode of action of parent molecule against Lepidoptera and locusts. Group: Pharmaceutical. CAS No. 106500-25-8. Pack Sizes: 10 mg. Product ID: B1370-382851. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azadirachtin H | Azadirachtin H is a naturally occurring metabolite isolated from A. indica. Group: Pharmaceutical. CAS No. 124788-15-1. Pack Sizes: 1 mg. Product ID: B1370-449747. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azamulin Impurities | Azamulin Impurities, essential for pharmaceutical research, aid in the quality control and characterization of azamulin, a potent antibiotic. These impurities are crucial in determining the purity and stability of azamulin, ensuring its efficacy in treating Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA). They facilitate the development of safer, more effective antimicrobial therapies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azapentacene Impurities | Azapentacene Impurities, crucial in pharmaceutical research, contribute to the quality control and refinement of azapentacene, a molecule being explored for its potential in treating cancer. These impurities help understand degradation pathways and improve drug purity, ensuring the effectiveness and safety of future therapeutic developments. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azatadine Impurities | Azatadine Impurities act as quintessential reference standards in the nuanced analytical assessment and stringent quality control of azatadine formulations, a therapeutic agent targeting allergic manifestations. These impurities crucially facilitate the detailed investigation of pharmacokinetics and safety profiles, thereby affirming the drug's efficacy in mitigating hay fever, allergic rhinitis, and urticaria. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azathioprine Impurities | Azathioprine Impurities, generated during azathioprine synthesis, hold critical significance in maintaining drug integrity and safety for managing autoimmune conditions, such as rheumatoid arthritis and inflammatory bowel disease. Their identification and quantification are vital for optimizing therapeutic effectiveness and reducing side effects, fundamentally impacting pharmaceutical quality assurance. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD0364 | AZD-0364 is a potent and selective ERK2 inhibitor, which has an IC50 value of 0.6 nM. AZD-0364 is measured in the A375 phospho-p90RSK assays with IC50s of 5.7 nM. AZD-0364 can inhibit the growth of a panel of cancer cell lines. The combination of Selumetinib and AZD-0364 ethanesulfonic acid results in a reduction in tumor growth. Group: Pharmaceutical. CAS No. 2097416-76-5. Pack Sizes: 25 mg. Product ID: B2693-291616. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD1981 | AZD1981, as a potent antagonist in a disease relevant cell system, inhibits DK-PGD2-induced CD11b expression in human eosinophils with IC50 of 10 nM. Group: Pharmaceutical. CAS No. 802904-66-1. Pack Sizes: 100 mg. Product ID: B2693-462263. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD3759 | AZD3759 is a n orally available inhibitor of the epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Upon oral administration, AZD3759 binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR. Group: Pharmaceutical. CAS No. 1626387-80-1. Pack Sizes: 1 g. Product ID: B0084-470884. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD3965 | AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Group: Pharmaceutical. CAS No. 1448671-31-5. Pack Sizes: 25 mg. Product ID: B2693-463251. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-4547 | AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. Group: Pharmaceutical. CAS No. 1035270-39-3. Pack Sizes: 100 mg. Product ID: B0084-456576. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-4635 | AZD-4635 is an orally available adenosine 2A receptor (A2AR) inhibitor. Group: Pharmaceutical. CAS No. 1321514-06-0. Pack Sizes: 25 mg. Product ID: B0084-260293. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-4694 | AZD-4694 is a bio-active chemical compound and is used as a diagnostic imaging agent. It was developed by AstraZeneca. Group: Pharmaceutical. CAS No. 1054629-49-0. Pack Sizes: 1 mg. Product ID: B2693-475025. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-5069 | AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neutrophil migration into the airways in patients with COPD. AZD-5069 was shown to inhibit binding of radiolabeled CXCL8 to human CXCR2 with a pIC50 value of 9.1. Group: Pharmaceutical. CAS No. 878385-84-3. Pack Sizes: 25 mg. Product ID: B2693-470942. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD 5153 | AZD5153 is a potent, selective, and orally available inhibitor of the bromodomain and extraterminal (BET). It can simultaneously bind two bromodomains in BRD4 with the IC50 value of 5 nM, which has been shown to increase antitumor activity in multiple xenograft models of acute myeloid leukemia, multiple myeloma, and diffuse large B cell lymphoma. AZD5153 also shows enhanced potency as a result of bivalent binding and a clear correlation between BRD4 activity and cellular potency. Group: Pharmaceutical. CAS No. 1869912-39-9. Pack Sizes: 25 mg. Product ID: B1370-291088. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD5305 | AZD5305 is a potent, selective and orally active inhibitor of PARP1 with IC50 of 3 nM in wild-type A549 lung cancer cells. AZD5305 is under clinical trials for advanced solid tumor treatment. Group: Pharmaceutical. CAS No. 2589531-76-8. Pack Sizes: 200 mg. Product ID: B1370-381573. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-5363 | AZD-5363 is an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AZD-5363 binds to and inhibits all AKT isoforms. This agent may be used as monotherapy or combination therapy for a variety of human cancers. Group: Pharmaceutical. CAS No. 1143532-39-1. Pack Sizes: 10 mg. Product ID: B2693-457058. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD6738 | AZD6738 is an orally active, and selective ATR kinase inhibitor with IC50 of 1 nM. Phase 1/2. Group: Pharmaceutical. CAS No. 1352226-88-0. Pack Sizes: 20 mg. Product ID: B0084-470841. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-7594 | AZD-7594 is an inhaled selective glucocorticoid receptor (GCCR) modulator. Group: Pharmaceutical. CAS No. 1196509-60-0. Pack Sizes: 10 mg. Product ID: B0084-260278. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD8186 | AZD 8186 is a selective PI3Kβ/δ inhibitor (IC50= 0.003 μM for PI3Kβ, and 0.017 μM for PI3Kδ) with potential antineoplastic activity. It shows no significant binding against a panel of 442 other kinases when tested at a concentration of 10 μM and exhibits high oral efficacy in mouse cancer models. Group: Pharmaceutical. CAS No. 1627494-13-6. Pack Sizes: 50 mg. Product ID: B0084-470885. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-8931 | Sapitinib, also known as AZD-8931, is an erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. AZD8931 binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. Group: Pharmaceutical. CAS No. 848942-61-0. Pack Sizes: 100 mg. Product ID: B0084-286313. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-9291 | AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. AZD 9291 is an irreversible inhibitor of epidermal growth factor receptor (EGFR) sensitizing and T790M resistance mutations (IC50s = 15-17 nM) while sparing the wild-type form of the receptor (IC50 = 480 nM). It binds the related IGF1R and hERG receptors with significantly reduced potency (IC50s = 2.9 and 16.2 μM, respectively). Uses: For research used only. Group: Pharmaceutical. CAS No. 1421373-65-0. Pack Sizes: 2.5 g. Product ID: B0084-462147. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD9291DA | AZD9291-DA is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. Uses: For research used only. Group: Pharmaceutical. CAS No. 1421372-66-8. Pack Sizes: 1 g. Product ID: B0084-462681. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-9291 mesylate | AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. It inhibits both activating and resistant EGFR mutations while sparing the normal form of EGFR that is present in normal skin and gut cells, thereby reducing the side effects encountered with currently available medicines. Group: Pharmaceutical. CAS No. 1421373-66-1. Pack Sizes: 100 mg. Product ID: B0084-463232. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD9496 | AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. Group: Pharmaceutical. CAS No. 1639042-08-2. Pack Sizes: 25 mg. Product ID: B0084-470890. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azelaic acid | 100g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Research Organics & Inorganics. Formula: HOOC(CH2)7COOH. CAS No. 123-99-9. Prepack ID : 31437119-100g. Molecular Weight : 188.22. | |
| Azelaic acid, Flake form | 100g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Organics. Formula: HO2C(CH2)7CO2H. CAS No. 123-99-9. Prepack ID : 90028396-100g. Molecular Weight : 188.22. | |
| Azelastine HCl | Azelastine HCl is a potent, second-generation, selective, histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor. Uses: Histamine antagonist. Group: Pharmaceutical. CAS No. 79307-93-0. Pack Sizes: 1 g. Product ID: B0084-098591. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azelastine Impurities | Azelastine Impurities are crucial in pharmaceutical research and development, serving as reference standards in the synthesis and quality control of azelastine hydrochloride, an antihistamine used to treat allergic rhinitis and conjunctivitis. These impurities aid in ensuring drug purity and efficacy by facilitating the identification of potential contaminants. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azelic Acid | Azelic Acid. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 123-99-9. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| Azeliragon | Azeliragon is a potent and orally active RAGE inhibitor as a potential treatment for patients with mild-to-moderate Alzheimer's disease (AD). Uses: A potent and orally active rage inhibitor. Group: Pharmaceutical. CAS No. 603148-36-3. Pack Sizes: 50 mg. Product ID: B0084-221743. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azelnidipine Impurities | Azelnidipine Impurities, essential reference substances, underpin the quality control and progression of azelnidipine, a calcium channel antagonist targeting hypertension. By ensuring azelnidipine's safety, efficacy, and stability, these impurities are pivotal in advancing cardiovascular therapeutic strategies, marking them as vital in pharmaceutical innovation and research endeavors. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azido-PEG2-NHS ester | Azido-PEG2-NHS ester is a non-cleavable 2-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Group: Pharmaceutical. CAS No. 1312309-64-0. Pack Sizes: 500 mg. Product ID: BADC-00409. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azido-PEG3-acetic acid | N3-PEG3-CH2COOH is a PROTAC linker, which refers to the alkyl/ether composition. N3-PEG3-CH2COOH can be used in the synthesis of a series of PROTACs. N3-PEG3-CH2COOH is a PEG derivative containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. Group: Pharmaceutical. CAS No. 172531-37-2. Pack Sizes: 5 g. Product ID: B1370-291925. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azido-PEG4-alcohol | It is useful as a spacer and linker between compounds. Group: Pharmaceutical. CAS No. 86770-67-4. Pack Sizes: 5 g. Product ID: BAT-001233. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azilsartan-[d5] | Azilsartan-[d5] is the labelled analogue of Azilsartan, which is an angiotensin II type 1 receptor antagonist and could be used against hypertension and inflammation. Group: Pharmaceutical. CAS No. 1346599-45-8. Pack Sizes: 5 mg. Product ID: BLP-011801. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azilsartan Impurities | Azilsartan Impurities occupy a critical niche in the biomedical sector, underscoring the integrity and safety of antihypertensive agents like Azilsartan. These impurities are essential in pharmaceutical innovation and quality assessment, facilitating the detection and analysis of byproducts, thereby enhancing the therapeutic effectiveness and safety parameters of azilsartan-centric therapies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azilsartan medoxomil | Azilsartan Medoxomil is a potent angiotensin II type 1 (AT1) receptor antagonist that inhibits the RAAS, with an IC50 of 2.6 nM. It exhibits more than 10,000-fold selectivity over AT2. Azilsartan Medoxomil can be used for the treatment of mild to moderate essential hypertension. Uses: The treatment of mild to moderate essential hypertension. Group: Pharmaceutical. CAS No. 863031-21-4. Pack Sizes: 200 mg. Product ID: B0084-451789. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
