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| Product | Description | |
|---|---|---|
| Auristatin F | Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. CAS No. 163768-50-1. Pack Sizes: 25 mg. Product ID: BBF-05829. Molecular formula: C40H67N5O8. Mole weight: 745.99. Custom synthesis is available. Send your inquiries for more information. |  London |
| Australian Chemical Suppliers Database | Australian Chemical Suppliers Database | Australian Chemical Suppliers |
| AUTOCLAVE BAGS | AUTOCLAVE BAGS, UK suppliers of laboratory chemicals wanted |  |
| AUTOCLAVE PRESTIGE 2100, | AUTOCLAVE PRESTIGE 2100,, Suppliers of UK laboratory chemicals wanted | |
| AUTOCLAVE TAPE | AUTOCLAVE TAPE, Suppliers of UK laboratory chemicals wanted | |
| Autotaxin modulator 1 | Autotaxin modulator 1 is a novel Autotaxin modulator. Group: Pharmaceutical. Alternative Names: 8-[(1R)-1-[8-(trifluoromethyl)-7-[4-(trifluoromethyl)cyclohexyl]oxynaphthalen-2-yl]ethyl]-8-azabicyclo[3.2.1]octane-3-carboxylic acidAutotaxin modulator 1; SCHEMBL15559445; SCHEMBL16934494; CS-4200; CS 4200; CS4200. CAS No. 1548743-69-6. Pack Sizes: 1mg;1g;10g. Product ID: 1548743-69-6. Molecular formula: C28H31F6NO3. Mole weight: 543.54. Custom synthesis is available. Send your inquiries for more information. | London |
| AV-412 | AV-412 is a second-generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR/HER2 inhibitor AV-412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may suppress tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. This agent may be active against EGFR/HER2-expressing tumor cells that are resistant to first-generation kinase inhibitors. EGFR and HER2 are receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularization. Group: Pharmaceutical. Alternative Names: AV 412; AV412; N-[4-(3-chloro-4-fluoroanilino)-7-[3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl]quinazolin-6-yl]prop-2-enamide. CAS No. 451492-95-8. Pack Sizes: 20 mg. Product ID: B0084-324573. Molecular formula: C27H28ClFN6O. Mole weight: 507.01. Custom synthesis is available. Send your inquiries for more information. | London |
| Avagacestat | BMS-708163 is a potent and orally bioavailable inhibitor of γ-secretase that more potently inhibits the cleavage of APP (IC50 = 0.30 nM) to Aβ40 than signaling through Notch (IC50s = 58 nM). Uses: Gamma secretase inhibitors and modulators. Group: Pharmaceutical. Alternative Names: Avagacestat; BMS 708163; (2R)-2-[(4-chlorophenyl)sulfonyl-[[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide. CAS No. 1146699-66-2. Pack Sizes: 50 mg. Product ID: B0084-286394. Molecular formula: C20H17ClF4N4O4S. Mole weight: 520.89. Custom synthesis is available. Send your inquiries for more information. | London |
| Avanafil | A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction. Group: Pharmaceutical. Alternative Names: TA-1790; TA 1790; TA1790; Avanafil; trade name: Stendra; Spedra. CAS No. 330784-47-9. Pack Sizes: 1mg;1g;10g. Product ID: NP3542. Molecular formula: C23H26ClN7O3. Mole weight: 483.95064. Custom synthesis is available. Send your inquiries for more information. | London |
| Avapritinib | BLU-285 is a potent and selective inhibitor of exon 17 mutant KIT (IC50 = 0.27 nM for KIT D816V). BLU-285 showed dose-dependent, robust anti-tumor efficacy in a TKI-resistant KIT exon 11/17 mutant GIST PDX model through inhibition of tumor growth, proliferation, KIT signaling and induction of apoptosis. Group: Pharmaceutical. Alternative Names: (1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine; BLU-285; BLU 285; BLU285; UNII-513P80B4YJ; SCHEMBL16652297. CAS No. 1703793-34-3. Pack Sizes: 10 mg. Product ID: B0084-007732. Molecular formula: C26H27FN10. Mole weight: 498.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Avasopasem manganese | Avasopasem manganese is a superoxide dismutase mimetic drug candidate. This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19. Group: Pharmaceutical. Alternative Names: GC-4419; GC4419; GC 4419; M 40419; M40419; M-40419. CAS No. 435327-40-5. Pack Sizes: 1mg;1g;10g. Product ID: 435327-40-5. Molecular formula: C21H35Cl2MnN5. Mole weight: 483.38. Custom synthesis is available. Send your inquiries for more information. | London |
| Avatrombopag | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Group: Pharmaceutical. Alternative Names: AKR-501; AKR 501; AKR501; YM477; YM-477; YM 477; E5501; AS 1670542; AS1670542; AS-1670542. CAS No. 570406-98-3. Pack Sizes: 100 mg. Product ID: B2693-144359. Molecular formula: C29H34Cl2N6O3S2. Mole weight: 649.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Avatrombopag maleate | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Group: Pharmaceutical. CAS No. 677007-74-8. Pack Sizes: 100 mg. Product ID: B2693-216033. Molecular formula: C33H38Cl2N6O7S2. Mole weight: 765.7. Custom synthesis is available. Send your inquiries for more information. | London |
| Avermectin B1a | It is produced by the strain of Streptomyces avermitilis. Avermectin B1a is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis. It is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. It also acts as an insecticide and acaricide. Uses: Active ingredient in some commercial ant bait traps. Group: Pharmaceutical. Alternative Names: Ivermectin EP Impurity A; Abamectin B1a; Doramectin Impurity 3. CAS No. 65195-55-3. Pack Sizes: 1mg;1g;10g. Product ID: BBF-00614. Molecular formula: C48H72O14. Mole weight: 873.08. Custom synthesis is available. Send your inquiries for more information. | London |
| Avermectin B1b | Avermectin B1b is the minor component of the commercially available anthelmintic marketed as Abamectin. It is used broadly against nematodes, ticks, flies, and ants. Group: Pharmaceutical. Alternative Names: Ivermectin EP Impurity B; 5-O-Demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-avermectin A1a; Doramectin Impurity 2. CAS No. 65195-56-4. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04030. Molecular formula: C47H70O14. Mole weight: 859.05. Custom synthesis is available. Send your inquiries for more information. | London |
| Avermectin B2a | Avermectin B2a is produced by the strain of Streptomyces avermitilis. It stimulates nerve cells to release Y-aminobutyric acid (GABA), which blocks the transmission of signals from the central nervous system to the motor nerve. It is not resistant to bacteria and fungi, but has strong activity to nematode parasites such as ancylostoma and Pteria, as well as insects such as flies. Abamectin B1a has the highest activity. Ivermectin obtained by catalytic hydrogenation contains 22 23- dihydroabamectin B1a (above 80%) and 22 23 dioxabamectin B1b (below 20%). Less active than B1a but less toxic. Used as repellent (subcutaneous or oral) for cattle, sheep and pigs, it is also effective against human filariasis. Group: Pharmaceutical. Alternative Names: Ivermectin EP Impurity C; (23S)-5-O-demethyl-23-hydroxy-22,23-dihydro-avermectin A1a. CAS No. 65195-57-5. Pack Sizes: 1mg;1g;10g. Product ID: BBF-00230. Molecular formula: C48H74O15. Mole weight: 891.09. Custom synthesis is available. Send your inquiries for more information. | London |
| Avibactam Impurity 6 | An impurity of Avibactam, a non-β lactam β-lactamase inhibitor that inactivates some β-lactamases. Group: Pharmaceutical. Alternative Names: (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (1R,2S,5R)-7-Oxo-6-(phenylmethoxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide. CAS No. 1192651-49-2. Pack Sizes: 25 mg. Product ID: B2694-467077. Molecular formula: C14H17N3O3. Mole weight: 275.31. Custom synthesis is available. Send your inquiries for more information. | London |
| Avibactam sodium | 100mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C7H10N3O6S ·Na. CAS No. 1192491-61-4. Prepack ID : 90023818-100mg. Molecular Weight : 287.2. |  |
| Avibactam Sodium Salt | Avibactam Sodium Salt, a novel non-?-lactam ?-lactamase inhibitor, binds covalently to Ambler class A ?-lactamases, including KPCs, Ambler class C and some class D b-lactamases. In combination with ceftazidime, Avibactam is a new drug application for avibactam , and was approved by the FDA on February 25, 2015, to treat complicated urinary tract and complicated intra-abdominal Infections caused by antibiotic resistant-pathogens. Avibactam has limited intrinsic antimicrobial activity but restores the in vitro activity of b-lactams including ceftazidime, ceftaroline, the active metabolite of ceftaroline fosamil, and aztreonam against ESBL-producing pathogens. Group: Pharmaceutical. Alternative Names: sodium (2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[321]octan-6-yl sulfate; NXL104; NXL-104; NXL 104; Avibactam; Avibactam sodium. CAS No. 1192491-61-4. Pack Sizes: 500 mg. Product ID: B0084-465274. Molecular formula: C7H10N3NaO6S. Mole weight: 287.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Avicularin | Avicularin, a natural plant flavonoid isolated from the herbs of Polygonum aviculare, exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. By decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase, avicularin can inhibit the accumulation of the intracellular lipids. Uses: Anti-inflammatory. Group: Pharmaceutical. Alternative Names: Fenicularin; Quercetin 3-alpha-L-arabinofuranoside; Avicularoside. CAS No. 572-30-5. Pack Sizes: 10 mg. Product ID: NP1949. Molecular formula: C20H18O11. Mole weight: 434.4. Custom synthesis is available. Send your inquiries for more information. | London |
| Avilamycin | Avilamycin is an antimicrobial agent that is active mainly against Gram-positive bacteria and is used against methicillin-resistant staphylococcus. Uses: Anti-bacterial agents. Group: Pharmaceutical. Alternative Names: LY 048740; Maxus; Maxus 100; Maxus 200; Surmax; (2R,3S,4R,6S)-6-(((3a'R,4R,4'R,5S,6R,6'S,7a'R)-6'-(((2S,3R,4R,5S,6R)-2-(((2R,3S,4S,5S,6S)-6-(((2R,3aS,3a'R,6S,6'R,7R,7aR,7'S,7a'R)-7'-acetyl-7'-hydroxy-7-(isobutyryloxy)-6'-methyloctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl)oxy)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-3-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-4',6,7a'-trimethyloctahydro-4'H-spiro[pyran-2,2'-[1,3]dioxolo[4,5-c]pyran]-5-yl)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate. CAS No. 11051-71-1. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05825. Molecular formula: C61H88Cl2O32. Mole weight: 1404.24. Custom synthesis is available. Send your inquiries for more information. | London |
| Avilamycin A | Avilamycin A is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Group: Pharmaceutical. Alternative Names: Flambamycin, 23-deoxy-. CAS No. 69787-79-7. Pack Sizes: 1mg;1g;10g. Product ID: BBF-00233. Molecular formula: C61H88Cl2O32. Mole weight: 1404.23. Custom synthesis is available. Send your inquiries for more information. | London |
| Aviptadil | Aviptadil Acetate is an analog of vasoactive intestinal polypeptide (VIP) as Vasoactive intestinal peptide receptor agonists for the treatment of erectile dysfunction. Uses: Vasoactive intestinal peptide receptor agonists. Group: Pharmaceutical. Alternative Names: H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2. CAS No. 40077-57-4. Pack Sizes: 5 mg. Product ID: BAT-006136. Molecular formula: C147H238N44O42S. Mole weight: 3325.8. Custom synthesis is available. Send your inquiries for more information. | London |
| AVL-292 | AVL-292, also known as CC-292, is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL-292 targets and covalently binds to BTK, thereby preventing its activity. Uses: Protein kinase inhibitors. Group: Pharmaceutical. Alternative Names: CC-292; CC292; CC 292; AVL292; AVL 292; spebrutinib. CAS No. 1202757-89-8. Pack Sizes: 1 g. Product ID: B2693-462475. Molecular formula: C22H22FN5O3. Mole weight: 423.44. Custom synthesis is available. Send your inquiries for more information. | London |
| AVN-492 | AVN-492 is a novel potent and selective 5-HT6 receptor antagonist with Ki values of 91 pM and 170 nM for 5-HT6R and 5-HT2BR, respectively. Uses: Serotonin antagonists. Group: Pharmaceutical. Alternative Names: AVN-492; AVN 492; AVN492. 3-(benzenesulfonyl)-2-N,6-N,6-N,5,7-pentamethylpyrazolo[1,5-a]pyrimidine-2,6-diamine. CAS No. 1220646-23-0. Pack Sizes: 200 mg. Product ID: B0084-007690. Molecular formula: C17H21N5O2S. Mole weight: 359.45. Custom synthesis is available. Send your inquiries for more information. | London |
| Avobenzone | Avobenzone is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative. Group: Pharmaceutical. Alternative Names: Avobenzonum; Parsol 1789; Parsol1789; Parsol-1789; HSDB 7423; HSDB-7423; HSDB7423; 1,3-Propanedione, 1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)-; 1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione; 1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)propane-1,3-dione; 1-(4'-tert-Butylphenyl)-3-(4'-methoxyphenyl)propane-1,3-dione; 3-(4-Methoxyphenyl)-1-(4-tert-butylphenyl)-1,3-propanedione; 4-(1,1-Dimethylethyl)-4'-methoxydibenzoylmethane; 4-Methoxy-4'-tert-butyldibenzoylmethane; 4-tert-Butyl-4'-methoxydibenzoylmethane; Butylmethoxydibenzoylmethane; Escalol 517; Eusolex 9020; Milestab 1789; NeoHeliopan 357; Parsol 1789; Parsol A; Parsol RTM 1789; Photoplex; Solarom BMBM; Uvinul BMBM. CAS No. 70356-09-1. Pack Sizes: 500 g. Product ID: B2697-347173. Molecular formula: C20H22O3. Mole weight: 310.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Avobenzone | Avobenzone. Group: Uv absorbers. Categories: avobenzone; 70356-09-1. |  |
| Avo Benzone | Avo Benzone. Categories: Avobenzone. | |
| Avocado | Avocado. Group: Organic carrier oils. | |
| AVOCADO STONE | AVOCADO STONE - Our signature range of liquid botanical extracts |  England, Scotland |
| AWD 131-138 | AWD 131-138 is a partial agonist of GABAA receptor with low affinity for the benzodiazepine binding site. AWD 131-138 exhibits potent anticonvulsant and anxiolytic properties in rodent models. It is used as an antiepileptic drug for the treatment of canine idiopathic epilepsy. Group: Pharmaceutical. Alternative Names: AWD 131-138; AWD-131-138; AWD131-138; AWD 131138; Imepitoin; 3-(4-chlorophenyl)-5-morpholin-4-yl-4H-imidazol-2-one. CAS No. 188116-07-6. Pack Sizes: 10 mg. Product ID: B0084-244924. Molecular formula: C13H14ClN3O2. Mole weight: 279.724. Custom synthesis is available. Send your inquiries for more information. | London |
| Axinysone A | Axinysone A is a natural compound used in the research of cancer. Derived from natural sources, this product acts as a valuable inhibitor of specific signaling pathways involved in tumor growth and progression. Group: Pharmaceutical. Alternative Names: (-)-Axinysone A. CAS No. 1114491-57-4. Pack Sizes: 1 mg. Product ID: NP5852. Molecular formula: C15H22O2. Mole weight: 234.338. Custom synthesis is available. Send your inquiries for more information. | London |
| Axitinib | Axitinib (AG013736) is a tyrosine kinase inhibitor developed by Pfizer. Axitinib is a tyrosine kinase inhibitor that blocks the activation of VEGFR1, VEGFR2, VEGFR3, c-kit, and PDGFRβ (IC50 = 1.2, 0.25, 0.29, 1.7, and 1.6 nM, respectively). It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models. Uses: Protein kinase inhibitors. Group: Pharmaceutical. Alternative Names: AG 013736; N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide; Inlyta. CAS No. 319460-85-0. Pack Sizes: 5 g. Product ID: NP3631. Molecular formula: C22H18N4OS. Mole weight: 386.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Axitinib Impurity 2 | An impurity of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Group: Pharmaceutical. Alternative Names: 2,2'-((6,6'-(2,4-Di(pyridin-2-yl)cyclobutane-1,3-diyl)bis(1H-indazole-6,3-diyl))bis(sulfanediyl))bis(N-methylbenzamide). CAS No. 1428728-83-9. Pack Sizes: 5 mg. Product ID: B2694-467092. Molecular formula: C44H36N8O2S2. Mole weight: 772.96. Custom synthesis is available. Send your inquiries for more information. | London |
| Axitinib sulfoxide | A major metabolite of Axitinib, a tyrosine kinase inhibitor used for the treatment of kidney cancer. Group: Pharmaceutical. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]sulfinyl]-benzamide; Axitinib Impurity A. CAS No. 1347304-18-0. Pack Sizes: 10 mg. Product ID: B2694-467095. Molecular formula: C22H18N4O2S. Mole weight: 402.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Ayanin | Ayanin isolated from the rhizomes of Curcuma aromatica. Group: Pharmaceutical. Alternative Names: QUERCETIN 3,7,4'-TRIMETHYL ETHER;AYANIN;2-(3-Hydroxy-4-methoxyphenyl)-3,7-dimethoxy-5-hydroxy-4H-1-benzopyran-4-one;3',5-Dihydroxy-3,4',7-trimethoxyflavone; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxychromen-4-one. CAS No. 572-32-7. Pack Sizes: 1 mg. Product ID: NP2101. Molecular formula: C18H16O7. Mole weight: 344.3. Custom synthesis is available. Send your inquiries for more information. | London |
| AY-NH2 | AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Group: Pharmaceutical. Alternative Names: PAR-4 Agonist Peptide, amide; L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide; PAR-4-AP; Proteinase-activated Receptor 4 Activating Peptide. CAS No. 352017-71-1. Pack Sizes: 5 mg. Product ID: BAT-006106. Molecular formula: C34H48N8O7. Mole weight: 680.79. Custom synthesis is available. Send your inquiries for more information. | London |
| AZ5104 | AZ5104 is a potent EGFR inhibitor and a derivative of AZD 9291. AZ5104 exhibits reduced selectivity against wild-type EGFR but five-fold potentcy compared to AZD 9291. Group: Pharmaceutical. Alternative Names: AZ-5104; AZ 5104; N-[2-[2-(dimethylamino)ethyl-methylamino]-5-[[4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-4-methoxyphenyl]prop-2-enamide. CAS No. 1421373-98-9. Pack Sizes: 25 mg. Product ID: B0084-470856. Molecular formula: C27H31N7O2. Mole weight: 485.592. Custom synthesis is available. Send your inquiries for more information. | London |
| AZ7371 | AZ7371 is a novel non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with IC50 of 10 nM. Group: Pharmaceutical. Alternative Names: AZ-7371; AZ 7371; TBA-7371; DprE1-IN-1. CAS No. 1494675-86-3. Pack Sizes: 50 mg. Product ID: B2693-470868. Molecular formula: C18H21N5O3. Mole weight: 355.4. Custom synthesis is available. Send your inquiries for more information. | London |
| AZ-960 | AZ-960 is an ATP-competitive inhibitor of JAK2 with Ki value of 0.45 nM. It inhibits proliferation in a SET-2 human megakaryoblastic cell line harboring the JAK2V617F mutation with GI50 value of 33 nM. Group: Pharmaceutical. Alternative Names: (S)-5-Fluoro-2-((1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile; 3-Pyridinecarbonitrile, 5-fluoro-2-(((1S)-1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)-; 5-Fluoro-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-6-[(5-methyl-1H-pyrazol-3-yl)amino]nicotinonitrile. CAS No. 905586-69-8. Pack Sizes: 50 mg. Product ID: B1370-286345. Molecular formula: C18H16F2N6. Mole weight: 354.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Azacytidine-[13C5] | Labelled Azacytidine, produced by the strain of Streptoverticillium ladakanus var. ladakanus UC-2654. Azacitidine (Vidaza) is a chemotherapy drug used to treat conditions that affect the blood and the bone marrow, called myelodysplastic syndromes (MDS). It may also be used to treat other cancers, such as acute myeloid leukaemia (AML) or chronic myelomonocytic leukaemia (CMML). It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes (IC50s = 2.4 and 2.6 μM for in vitro anti-myeloma activity) and cancer (IC50s ~ 0.4 μM for inhibiting proliferation of various cancer cell lines). It can also act as a demethylating agent by inhibiting DNA methyltransferase. Group: Pharmaceutical. Alternative Names: 4-Amino-1-[3,4-dihydroxy-5-(hydroxy(113C)methyl)(2,3,4,5-13C4)oxolan-2-yl]-1,3,5-triazin-2-one. Pack Sizes: 1 mg. Product ID: BLP-003371. Molecular formula: C3[13C]5H12N4O5. Mole weight: 249.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Azadirachtin B | Azadirachtin B is a drug analog of azadirachtin which was investigated in agrochemical studies of bioregulators for the antifeedant mode of action of parent molecule against Lepidoptera and locusts. Group: Pharmaceutical. Alternative Names: Deacetylazadirachtinol; Azadirachtinol deacetyl; 3-tigloyl-azadirachtol; 3-Tigloylazadirachtol. CAS No. 106500-25-8. Pack Sizes: 10 mg. Product ID: B1370-382851. Molecular formula: C33H42O14. Mole weight: 662.68. Custom synthesis is available. Send your inquiries for more information. | London |
| Azadirachtin H | Azadirachtin H is a naturally occurring metabolite isolated from A. indica. Group: Pharmaceutical. Alternative Names: 11Alpha-Azadirachtin H. CAS No. 124788-15-1. Pack Sizes: 1 mg. Product ID: B1370-449747. Molecular formula: C33H42O14. Mole weight: 662.68. Custom synthesis is available. Send your inquiries for more information. | London |
| Azaleatin | Azaleatin is an O-methylated flavonol, a type of flavonoid. It was first isolated from the flowers of Rhododendron mucronatum in 1956 and has since been recorded in forty-four other Rhododendron species, in Plumbago capensis, in Ceratostigma willmottiana and in Carya pecan. It has been also been found in the leaves of Eucryphia. It is the 3-O-α-L-rhamnoside of azaleatin. Group: Pharmaceutical. Alternative Names: 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-5-methoxy-4H-1-benzopyran-4-one; 3,3',4',7-Tetrahydroxy-5-methoxyflavone; 5-O-Methyl quercetin; Quercetin 5-Methyl Ether; 2-(3,4-Dihydroxycyclohexa-2,4-dien-1-yl)-3,7-dihydroxy-5-methoxy-4H-chromen-4-one. CAS No. 529-51-1. Pack Sizes: 25 mg. Product ID: B1370-093812. Molecular formula: C16H12O7. Mole weight: 316.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Azamulin | Azamulin is an azole derivative of pleuromutilin. Azamulin is a highly selective inhibitor of cytochrome P450 3A4 (CYP3A4). Group: Pharmaceutical. Alternative Names: Azamulinum. CAS No. 76530-44-4. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04090. Molecular formula: C24H36N4O4S. Mole weight: 476.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Azasetron | Azasetron is an antiemetic agent that acts as a 5-HT3 receptor antagonist. Group: Pharmaceutical. Alternative Names: Nazasetron; 6-Chloro-4-methyl-3-oxo-N-(quinuclidin-3-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide; (±)-6-Chloro-3,4-dihydro-4-methyl-3-oxo-N-3-quinuclidinyl-2H-1,4-benzoxazine-8-carboxamide. CAS No. 123040-69-7. Pack Sizes: 1mg;1g;10g. Product ID: 123040-69-7. Molecular formula: C17H20ClN3O3. Mole weight: 349.81. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD0364 | AZD-0364 is a potent and selective ERK2 inhibitor, which has an IC50 value of 0.6 nM. AZD-0364 is measured in the A375 phospho-p90RSK assays with IC50s of 5.7 nM. AZD-0364 can inhibit the growth of a panel of cancer cell lines. The combination of Selumetinib and AZD-0364 ethanesulfonic acid results in a reduction in tumor growth. Group: Pharmaceutical. Alternative Names: AZD-0364; AZD 0364; tizaterkib. CAS No. 2097416-76-5. Pack Sizes: 25 mg. Product ID: B2693-291616. Molecular formula: C24H24F2N8O2. Mole weight: 494.5. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD1981 | AZD1981, as a potent antagonist in a disease relevant cell system, inhibits DK-PGD2-induced CD11b expression in human eosinophils with IC50 of 10 nM. Group: Pharmaceutical. Alternative Names: AZD1981; AZD 1981; AZD-1981. CAS No. 802904-66-1. Pack Sizes: 100 mg. Product ID: B2693-462263. Molecular formula: C19H17ClN2O3S. Mole weight: 388.866. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD3759 | AZD3759 is a n orally available inhibitor of the epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Upon oral administration, AZD3759 binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR. Group: Pharmaceutical. Alternative Names: AZD3759; AZD-3759; AZD 3759. CAS No. 1626387-80-1. Pack Sizes: 1 g. Product ID: B0084-470884. Molecular formula: C22H23ClFN5O3. Mole weight: 459.91. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD3965 | AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Group: Pharmaceutical. Alternative Names: (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AZD3965; AZD-3965; AZD 3965. CAS No. 1448671-31-5. Pack Sizes: 25 mg. Product ID: B2693-463251. Molecular formula: C21H24F3N5O5S. Mole weight: 515.51. Custom synthesis is available. Send | London |
| AZD-4547 | AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. Group: Pharmaceutical. Alternative Names: AZD-4547; AZD 4547; AZD4547; N-{3-[2-(3,5-Dimethoxyphenyl)ethyl]-1h-Pyrazol-5-Yl}-4-[(3r,5s)-3,5-Dimethylpiperazin-1-Yl]benzamide. CAS No. 1035270-39-3. Pack Sizes: 100 mg. Product ID: B0084-456576. Molecular formula: C26H33N5O3. Mole weight: 463.582. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-4635 | AZD-4635 is an orally available adenosine 2A receptor (A2AR) inhibitor. Group: Pharmaceutical. Alternative Names: AZD-4635; AZD 4635; AZD4635; HTL-1071; HTL 1071; HTL1071; 6-(2-chloro-6-methylpyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine. CAS No. 1321514-06-0. Pack Sizes: 25 mg. Product ID: B0084-260293. Molecular formula: C15H11ClFN5. Mole weight: 315.736. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-4694 | AZD-4694 is a bio-active chemical compound and is used as a diagnostic imaging agent. It was developed by AstraZeneca. Group: Pharmaceutical. Alternative Names: AZD 4694; AZD-4694; AZD4694; NAV4694; NAV 4694; NAV-4694; Flutafuranol; 2-(2-Fluoro-6-methylaminopyridin-3-yl)benzofuran-5-ol. CAS No. 1054629-49-0. Pack Sizes: 1 mg. Product ID: B2693-475025. Molecular formula: C14H11FN2O2. Mole weight: 258.25. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-5069 | AZD-5069 is a potent and selective CXCR2 antagonist with the potential to inhibit neutrophil migration into the airways in patients with COPD. AZD-5069 was shown to inhibit binding of radiolabeled CXCL8 to human CXCR2 with a pIC50 value of 9.1. Group: Pharmaceutical. Alternative Names: AZD-5069; AZD 5069; AZD5069. CAS No. 878385-84-3. Pack Sizes: 25 mg. Product ID: B2693-470942. Molecular formula: C18H22F2N4O5S2. Mole weight: 476.51. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD 5153 | AZD5153 is a potent, selective, and orally available inhibitor of the bromodomain and extraterminal (BET). It can simultaneously bind two bromodomains in BRD4 with the IC50 value of 5 nM, which has been shown to increase antitumor activity in multiple xenograft models of acute myeloid leukemia, multiple myeloma, and diffuse large B cell lymphoma. AZD5153 also shows enhanced potency as a result of bivalent binding and a clear correlation between BRD4 activity and cellular potency. Group: Pharmaceutical. Alternative Names: AZD-5153; AZD5153; (R)-4-(2-(4-(1-(3-methoxy-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenoxy)ethyl)-1,3-dimethylpiperazin-2-one. CAS No. 1869912-39-9. Pack Sizes: 25 mg. Product ID: B1370-291088. Molecular formula: C25H33N7O3. Mole weight: 479.57. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD5305 | AZD5305 is a potent, selective and orally active inhibitor of PARP1 with IC50 of 3 nM in wild-type A549 lung cancer cells. AZD5305 is under clinical trials for advanced solid tumor treatment. Group: Pharmaceutical. Alternative Names: Saruparib; AZD 5305; AZD-5305. CAS No. 2589531-76-8. Pack Sizes: 200 mg. Product ID: B1370-381573. Molecular formula: C22H26N6O2. Mole weight: 406.48. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-5363 | AZD-5363 is an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AZD-5363 binds to and inhibits all AKT isoforms. This agent may be used as monotherapy or combination therapy for a variety of human cancers. Group: Pharmaceutical. Alternative Names: AZD5363; AZD 5363; Capivasertib. CAS No. 1143532-39-1. Pack Sizes: 10 mg. Product ID: B2693-457058. Molecular formula: C21H25ClN6O2. Mole weight: 428.9152. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD6738 | AZD6738 is an orally active, and selective ATR kinase inhibitor with IC50 of 1 nM. Phase 1/2. Group: Pharmaceutical. Alternative Names: AZD-6738; AZD 6738. CAS No. 1352226-88-0. Pack Sizes: 20 mg. Product ID: B0084-470841. Molecular formula: C20H24N6O2S. Mole weight: 412.51. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-7594 | AZD-7594 is an inhaled selective glucocorticoid receptor (GCCR) modulator. Group: Pharmaceutical. Alternative Names: AZD-7594; AZD 7594; AZD7594; AZ13189620; AZ-13189620; AZ 13189620; 3-[5-[(1R,2S)-2-(2,2-difluoropropanoylamino)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy]indazol-1-yl]-N-[(3R)-oxolan-3-yl]benzamide. CAS No. 1196509-60-0. Pack Sizes: 10 mg. Product ID: B0084-260278. Molecular formula: C32H32F2N4O6. Mole weight: 606.627. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD8186 | AZD 8186 is a selective PI3Kβ/δ inhibitor (IC50= 0.003 μM for PI3Kβ, and 0.017 μM for PI3Kδ) with potential antineoplastic activity. It shows no significant binding against a panel of 442 other kinases when tested at a concentration of 10 μM and exhibits high oral efficacy in mouse cancer models. Group: Pharmaceutical. Alternative Names: (R)-8-(1-((3,5-difluorophenyl)amino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide; AZD8186; AZD 8186; AZD-8186. CAS No. 1627494-13-6. Pack Sizes: 50 mg. Product ID: B0084-470885. Molecular formula: C24H25F2N3O4. Mole weight: 457.4. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-8931 | Sapitinib, also known as AZD-8931, is an erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. AZD8931 binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. Group: Pharmaceutical. Alternative Names: AZD8931; AZD 8931; Momelotinib; Sapitinib. CAS No. 848942-61-0. Pack Sizes: 100 mg. Product ID: B0084-286313. Molecular formula: C23H25ClFN5O3. Mole weight: 473.933. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-9291 | AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. AZD 9291 is an irreversible inhibitor of epidermal growth factor receptor (EGFR) sensitizing and T790M resistance mutations (IC50s = 15-17 nM) while sparing the wild-type form of the receptor (IC50 = 480 nM). It binds the related IGF1R and hERG receptors with significantly reduced potency (IC50s = 2.9 and 16.2 μM, respectively). Uses: For research used only. Group: Pharmaceutical. Alternative Names: Mereletinib; AZD9291; AZD 9291; Osimertinib. CAS No. 1421373-65-0. Pack Sizes: 2.5 g. Product ID: B0084-462147. Molecular formula: C28H33N7O2. Mole weight: 499.61. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD9291DA | AZD9291-DA is a des acryl analogue of AZD9291, which is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. Uses: For research used only. Group: Pharmaceutical. Alternative Names: AZD9291-Des acryl analogue; AZD9291 Des acryl precursor; Mutated EGFR-IN-1; N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)benzene-1,2,4-triamine; N1-(2-dimethylaminoethyl)-5-methoxy-N1-methyl-N4-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine; SCHEMBL14660679. CAS No. 1421372-66-8. Pack Sizes: 1 g. Product ID: B0084-462681. Molecular formula: C25H31N7O. Mole weight: 445.571. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-9291 mesylate | AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. It inhibits both activating and resistant EGFR mutations while sparing the normal form of EGFR that is present in normal skin and gut cells, thereby reducing the side effects encountered with currently available medicines. Group: Pharmaceutical. Alternative Names: Mereletinib mesylate; EGFR inhibitor; AZD9291 mesylate; AZD 9291 mesylate. CAS No. 1421373-66-1. Pack Sizes: 100 mg. Product ID: B0084-463232. Molecular formula: C29H37N7O5S. Mole weight: 595.71. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD9496 | AZD9496 is a potent and orally bioavailable selective estrogen receptor downregulator and antagonist. AZD9496 can induce ERα degradation in breast cancer cell lines at picomolar concentrations. Group: Pharmaceutical. Alternative Names: (E)-3-(3,5-difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic acid; AZD9496; AZD-9496; AZD 9496. CAS No. 1639042-08-2. Pack Sizes: 25 mg. Product ID: B0084-470890. Molecular formula: C25H25F3N2O2. Mole weight: 442.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Azelaic acid | 100g Pack Size. Group: Bioactive Small Molecules, Building Blocks, Research Organics & Inorganics. Formula: HOOC(CH2)7COOH. CAS No. 123-99-9. Prepack ID : 31437119-100g. Molecular Weight : 188.22. | |
| Azelaic acid | Azelaic acid. CAS No. 123-99-9. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| Azelaic acid | Azelaic acid is a naturally occurring saturated binary carboxylic acid containing nine carbon atoms, which is an important medium and long chain dibasic acid. Azelaic acid has been used in cosmetics for a long time. It has the function of inhibiting excessive secretion of oil, removing acne and freckles, and whitening skin, and it is very safe. Uses: Azelaic acid could be produced by ozone cracking of unsaturated fatty acid and is commonly used in grease, cosmetics and pharmaceuticals. Group: Pharmaceutical. Alternative Names: Finacea; Anchoic acid; Azelex; Lepargylic acid; 1,7-Heptanedicarboxylic acid; Skinoren; 1,9-Nonanedioic acid; Heptanedicarboxylic acid; n-Nonanedioic acid. CAS No. 123-99-9. Pack Sizes: 1 kg. Product ID: B1370-290997. Molecular formula: C9H16O4. Mole weight: 188.22. Custom synthesis is available. Send your inquiries for more information. | London |
| Azelaic Acid | Azelaic Acid. CAS No. 123-99-9. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. | Cenik Chemicals |
| Azelaic Acid (CAS 123-99-9) | Azelaic Acid (CAS 123-99-9). CAS No. 123-99-9. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. | Cenik Chemicals |
