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YKL-06-061 YKL-06-061 is a small molecule serine/threonine-protein kinase SIK1 inhibitor (Ki = 6.56 nM) that is hopefully developed to be a dermatologic drug impacting UV protection and skin cancer risk. It causes a dose-dependent increase in microphthalmia-associated transcription factor (MITF) mRNA expression during 3-hour function in normal human melanocytes, UACC62 human melanoma cells, and UACC257 human melanoma cells. Uses: A potential dermatologic drug. Group: Pharmaceutical. Alternative Names: YKL06-061; YKL 06-061; YKL-06061. CAS No. 2172617-15-9. Pack Sizes: 50 mg. Product ID: B0084-112344. Molecular formula: C30H37N7O2. Mole weight: 527.67. Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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