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10-methyl-9-(phenoxycarbonyl) Acridinium produces fluorescent compound 10-methyl-9-acridone upon oxidation with hydrogen peroxide, persulfates, and other oxidants in alkaline conditions. It has been used in chemiluminescence assays, enzyme, antigen, antibody, and hormone immunoassays. Group: Pharmaceutical. Alternative Names: 10-methyl-9-(phenoxycarbonyl)-acridinium, 1,1,1-trifluoromethanesulfonate; Phenyl 10-methylacridinium-9-carboxylate trifluoromethanesulfonate. CAS No. 161006-14-0. Pack Sizes: 10 mg. Product ID: B1370-285070. Molecular formula: C22H16F3NO5S. Mole weight: 463.43. Custom synthesis is available. Send your inquiries for more information.
1-Boc-4-(trifluoromethyl)piperidine-4-carboxylic Acid is a useful research chemical. Group: Pharmaceutical. Alternative Names: 1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-(trifluoromethyl)-4-piperidinecarboxylic acid; 1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)piperidine-4-carboxylic Acid; 4-trifluoromethylpiperidine-1,4-dicarboxylic acid mono-tert-butyl ester. CAS No. 495415-51-5. Pack Sizes: 500 mg. Product ID: BB026725. Molecular formula: C12H18F3NO4. Mole weight: 297.27. Custom synthesis is available. Send your inquiries for more information.
2,2'-Bis(trifluoromethyl)-4,4'-diamino biphenyl (TFMB) Uses: Pharmaceutical Research and Development. Group: Chemicals & Intermediates. CAS No. 341-58-2. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals: innovative sourcing and supply.
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2,3-Dichloro-5-(trifluoromethyl)pyridine
2,3-Dichloro-5-(trifluoromethyl)pyridine Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 69045-84-7. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply.
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2-Chloro-5- (trifluoromethyl) benzoic acid 98.5%
5g Pack Size. Group: Building Blocks, Organics. Formula: ClC6H3(CF3)CO2H. CAS No. 657-06-7. Prepack ID : 49574378-5g. Molecular Weight : 224.56.
2-Cyano-N-[4-(Trifluoromethyl)Phenyl]Acetamide
Leflunomide Impurity H is used to prepare aminothiophene carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. Group: Pharmaceutical. Alternative Names: 2-Cyano-α,α,α-trifluoro-p-acetotoluidide; Leflunomide EP Impurity H; Acetamide, 2-cyano-N-[4-(trifluoromethyl)phenyl]-; N-(4-trifluoromethylphenyl)cyanoacetamide; p-Acetotoluidide, 2-cyano-alpha,alpha,alpha-trifluoro-. CAS No. 24522-30-3. Pack Sizes: 1mg;1g;10g. Product ID: NP3106. Molecular formula: C10H7F3N2O. Mole weight: 228.18. Custom synthesis is available. Send your inquiries for more information.
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2-IODO-4-TRIFLUOROMETHYL ANILINE
2-IODO-4-TRIFLUOROMETHYL ANILINE Uses: Pharmaceutical R&D. Group: Iodides. CAS No. 163444-17-5. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals suppliers (Formerly Melrob-Eurolabs).
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3-(3'-Trifluoromethyl phenyl) propanol
3-(3'-Trifluoromethyl phenyl) propanol Uses: Pharmaceutical Research and Development. Group: Chemicals & Intermediates. CAS No. 78573-45-2. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals (Formerly Melrob-Eurolabs).
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3-(3-Trifluoromethyl phenyl)-propionaldehyde
3-(3-Trifluoromethyl phenyl)-propionaldehyde Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 21172-41-8. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals suppliers (Formerly Melrob-Eurolabs).
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3-(3-Trifluoromethylphenyl) Propionic acid
3-(3-Trifluoromethylphenyl) Propionic acid Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 585-50-2. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply.
An impurity of Celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. Alternative Names: 3-(4-methylphenyl)-5-(trifluoromethyl)pyrazole; 3-(Trifluoromethyl)-5-p-tolyl-1H-pyrazole; 3-(p-Tolyl)-5-(trifluoromethyl)-1H-pyrazole. CAS No. 219986-64-8. Pack Sizes: 10 mg. Product ID: B2694-309476. Molecular formula: C11H9F3N2. Mole weight: 226.2. Custom synthesis is available. Send your inquiries for more information.
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3,5-Bis (Trifluoromethyl) Acetophenone
3,5-Bis (Trifluoromethyl) Acetophenone Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 30071-93-3. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals suppliers (Formerly Melrob-Eurolabs).
An impurity of Nilotinib, which is a Bcr-Abl inhibitor with IC50 less than 36 nM. Group: Pharmaceutical. Alternative Names: 641571-16-6; 3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine3-(5-methylimidazol-1-yl)-5-(trifluoromethyl)aniline3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)anilinestarbld0029650. CAS No. 641571-16-6. Pack Sizes: 10 mg. Product ID: B1416-478156. Molecular formula: C11H10F3N3. Mole weight: 241.217. Custom synthesis is available. Send your inquiries for more information.
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3-(Trifluoromethyl)cinnamic acid
3-(Trifluoromethyl)cinnamic acid Uses: Pharmaceutical Research and Development. Group: Chemicals & Intermediates. CAS No. 779-89-5. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals: innovative sourcing and supply.
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3-Trifluoromethyl phenol
3-Trifluoromethyl phenol Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 98-17-9. Pack Sizes: Enquire for MOQ. Categories: NORDMANN Key intermediates and specialty chemicals suppliers.
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3-(Trifluoromethyl)phenyltrimethylammonium hydroxide, 5% w/v in methanol
3-(Trifluoromethyl)phenyltrimethylammonium hydroxide, 5% w/v in methanol. CAS No. 68254-41-1. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
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4-Isocyanato-2-(trifluoromethyl)benzonitrile
4-Isocyanato-2-(trifluoromethyl)benzonitrile (CAS# 143782-18-7 ) is a useful research chemical. Group: Pharmaceutical. Alternative Names: 4-isocyanato-2-(trifluoromethyl)benzonitrile; 4-isocyanato-2-(trifluoromethyl)benzonitrile. CAS No. 143782-18-7. Pack Sizes: 100 mg. Product ID: BB009667. Molecular formula: C9H3F3N2O. Mole weight: 212.13. Custom synthesis is available. Send your inquiries for more information.
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4-(Trifluoromethyl) Benzenesulphonamide
4-(Trifluoromethyl) Benzenesulphonamide. CAS No. 830-43-3. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
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4-Trifluoromethylphenyl boronic acid
4-Trifluoromethylphenyl boronic acid Uses: Pharmaceutical Research and Development. Group: Chemicals & Intermediates. CAS No. 128796-39-4. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals: innovative sourcing and supply.
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5-Methyl-3-(trifluoromethyl)-1H-pyrazole
5-Methyl-3-(trifluoromethyl)-1H-pyrazole. CAS No. 10010-93-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
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6-Trifluoromethylindole
1g Pack Size. Group: Building Blocks, Fluorinated Products, Indoles, Organics. Formula: C9H6F3N. CAS No. 13544-43-9. Prepack ID : 21450571-1g. Molecular Weight : 185.15.
A metabolite of Aprepitant. Group: Pharmaceutical. Alternative Names: Monobenzyl Fosaprepitant. CAS No. 889852-02-2. Pack Sizes: 1mg;1g;10g. Product ID: NP3713. Molecular formula: C30H28F7N4O6P. Mole weight: 704.54. Custom synthesis is available. Send your inquiries for more information.
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Choline bis(trifluoromethylsulfonyl)imde
Choline bis(trifluoromethylsulfonyl)imde. Group: Pharmaceutical. Alternative Names: 2-Hydroxy-N,N,N-trimethylethan-1-aminium bis((trifluoromethyl)sulfonyl)amide. CAS No. 827027-25-8. Pack Sizes: 100 g. Product ID: B1370-274158. Molecular formula: C7H14F6N2O5S2. Mole weight: 384.32. Custom synthesis is available. Send your inquiries for more information.
Diethylmethyl(2-methoxyethyl)ammonium bis(trifluoromethylsulfonyl)imide. Group: Pharmaceutical. Alternative Names: N,N-Diethyl-N-methyl-N-(2-methoxyethyl)ammonium bis(trifluoromethanesulfonyl)imide. CAS No. 464927-84-2. Pack Sizes: 5 g. Product ID: B2699-189240. Molecular formula: C10H20F6N2O5S2. Mole weight: 426.4. Custom synthesis is available. Send your inquiries for more information.
Diphenyl(trifluoromethyl)sulfonium trifluoromethanesulfonate can be used as a raw material for organic synthesis with styrene derivatives to synthesise 2-arylazo pyridine at low temperature. Group: Pharmaceutical. Alternative Names: Sulfonium, diphenyl(trifluoromethyl)-, 1,1,1-trifluoromethanesulfonate (1:1); Diphenyl-(trifluoromethyl)-sulfonium trifluoromethanesulfonate. CAS No. 147531-11-1. Pack Sizes: 10 g. Product ID: BB010209. Molecular formula: C14H10F6O3S2. Mole weight: 404.35. Custom synthesis is available. Send your inquiries for more information.
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Ethyl 2-(trifluoromethyl)nicotinate
Ethyl 2-(trifluoromethyl)nicotinate Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 208517-35-5. Pack Sizes: Enquire for MOQ. Categories: NORDMANN Key intermediates and specialty chemicals.
An impurity of Quinine. Quinine is a common medication that can be used to treat malaria and babesiosis. Group: Pharmaceutical. Alternative Names: N-((S)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)-3,5-bis(trifluoromethyl)benzenesulfonamide; N-[(8,9S)-6'-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide. CAS No. 1092116-26-1. Pack Sizes: 100 mg. Product ID: B1370-368444. Molecular formula: C28H27F6N3O3S. Mole weight: 599.59. Custom synthesis is available. Send your inquiries for more information.
N-[3,5-Bis(trifluoromethyl)phenyl]-N-[(8a,9S)-6-methoxy-9-cinchonanyl]thiourea (CAS# 852913-16-7 ) is a useful research chemical. Group: Pharmaceutical. Alternative Names: 9-(3-(3,5-Bis(trifluoromethyl)phenyl)thioureido)-(epi-quinine). CAS No. 852913-16-7. Pack Sizes: 1 g. Product ID: B2699-192360. Molecular formula: C29H28F6N4OS. Mole weight: 594.61. Custom synthesis is available. Send your inquiries for more information.
Pentane, 1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)-. Group: Pharmaceutical. Alternative Names: 3-Methoxyperfluoro(2-methylpentane); 1,1,1,2,3,4,4,5,5,5-Decafluoro-3-methoxy-2-(trifluoromethyl)pentane. CAS No. 132182-92-4. Pack Sizes: 500 g. Product ID: B1370-048335. Molecular formula: C7H3F13O. Mole weight: 350.08. Custom synthesis is available. Send your inquiries for more information.
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(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol
(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol. CAS No. 127852-28-2. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
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(R)-1-[3,5-Bis (Trifluoromethyl) Phenyl] Ethanol
(R)-1-[3,5-Bis (Trifluoromethyl) Phenyl] Ethanol Uses: Pharmaceutical R&D. Group: Chiral Building Blocks. Grades: White solid 99%+ ee 99%+. CAS No. 127852-28-2. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals suppliers (Formerly Melrob-Eurolabs).
(R)-1-(Naphthalen-1-yl)-N-(3-(trifluoromethyl)benzyl)ethanamine hydrochloride, is an impurity of Cinacalcet, which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels). Group: Pharmaceutical. Alternative Names: (αR)-α-Methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-1-naphthalenemethanamine Hydrochloride; Cinacalcet Impurity 18. CAS No. 1229225-42-6. Pack Sizes: 10 mg. Product ID: B2694-379696. Molecular formula: C20H19ClF3N. Mole weight: 365.82. Custom synthesis is available. Send your inquiries for more information.
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(S)-1-[3,5-Bis (Trifluoromethyl) Phenyl] Ethanol
(S)-1-[3,5-Bis (Trifluoromethyl) Phenyl] Ethanol Uses: Pharmaceutical Research and Development. Group: Chiral Building Blocks. Grades: White solid 99%+ ee 99%+. CAS No. 225920-05-8. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals: innovative sourcing and supply.
A cyclic haloalkyl substituted carboxylic acid used in the preparation of antiviral agents. Group: Pharmaceutical. Alternative Names: 4-(trifluoromethyl)cyclohexane-1-carboxylic acid. CAS No. 133261-33-3. Pack Sizes: 10 g. Product ID: B2699-300123. Molecular formula: C8H11F3O2. Mole weight: 196.17. Custom synthesis is available. Send your inquiries for more information.
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Tris(4-trifluoromethylphenyl)phosphine
Tris(4-trifluoromethylphenyl)phosphine is an intermediate used in organic synthesis. Group: Pharmaceutical. Alternative Names: tris[4-(trifluoromethyl)phenyl]phosphine; Tris(p-trifluoromethylphenyl)phosphine. CAS No. 13406-29-6. Pack Sizes: 25 g. Product ID: BB007873. Molecular formula: C21H12F9P. Mole weight: 466.28. Custom synthesis is available. Send your inquiries for more information.
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15-Keto Travoprost
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Group: Pharmaceutical. Alternative Names: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; 15-keto Fluprostenol Isopropyl Ester. CAS No. 404830-45-1. Pack Sizes: 25 mg. Product ID: B1911-313687. Molecular formula: C26H33F3O6. Mole weight: 498.54. Custom synthesis is available. Send your inquiries for more information.
([EMIM][N(Tf)2]) as a non-aqueous solvent, is advantageous over traditional aprotic polar organic solvents in electrochemical investigation of electroactive species since it has low vapor pressure, high thermal stability, good conductivity and a wide electrochemical window. Group: Pharmaceutical. Alternative Names: EMIIM; EMIM BTI; EMIM TFSI; [EMIM]NTF2; 3-Ethyl-1-methyl-1H-imidazol-3-ium bis((trifluoromethyl)sulfonyl)amide. CAS No. 174899-82-2. Pack Sizes: 100 g. Product ID: B1370-010421. Molecular formula: C8H11F6N3O4S2. Mole weight: 391.31. Custom synthesis is available. Send your inquiries for more information.
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(1R,2R,3R)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: (R,R,R)-Aprepitant; USP Aprepitant Related Compound A; Aprepitant Related Compound A; Aprepitant USP Related Compound A; Aprepitant R,R,R-Diastereomer; 3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one; 5-[[(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Aprepitant USP RC A (R,R,R-Diasteromer). CAS No. 1148113-53-4. Pack Sizes: 50 mg. Product ID: B2694-466699. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
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(1R,2S,3R)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: 5-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one. CAS No. 1185502-97-9. Pack Sizes: 50 mg. Product ID: B2694-466697. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
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(1R,2S,3S)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: 5-(((2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one. CAS No. 172822-28-5. Pack Sizes: 50 mg. Product ID: B2694-466702. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
London
(1S,2R,3R)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: 5-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one. CAS No. 1242175-34-3. Pack Sizes: 50 mg. Product ID: B2694-466696. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
London
(1S,2S,3S)-Aprepitant
An isomer of Aprepitant, a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: 5-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-3(2H)-one. CAS No. 1242175-40-1. Pack Sizes: 100 mg. Product ID: B2694-466704. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. Custom synthesis is available. Send your inquiries for more information.
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2-Methyl-Celecoxib
An impurity of Celecoxib, which is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Group: Pharmaceutical. Alternative Names: 4-[5-(2,4-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide. CAS No. 170570-09-9. Pack Sizes: 100 mg. Product ID: B0070-468627. Molecular formula: C18H16F3N3O2S. Mole weight: 395.41. Custom synthesis is available. Send your inquiries for more information.
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3-(Perfluoro-7-methyloctyl)-1,2-propenoxide
The chemical compound, 3-(Perfluoro-7-methyloctyl)-1,2-propenoxide, a commonly utilized reagent in research within the pharmaceutical industry, harbors potential for application in the synthesis of specific pharmaceuticals. Additionally, the compound's mechanisms may be studied for the purpose of investigating underlying causes of certain ailments. Group: Pharmaceutical. Alternative Names: (2,2,3,3,4,4,5,5,6,6,7,7,8,9,9,9-Hexadecafluoro-8-(trifluoromethyl)nonyl)oxirane. CAS No. 41925-33-1. Pack Sizes: 10 g. Product ID: B2699-117381. Molecular formula: C12H5F19O. Mole weight: 526.14. Custom synthesis is available. Send your inquiries for more information.
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4-Bromo-α,α,α-trifluorotoluene-[d4]
4-Bromo-α,α,α-trifluorotoluene-[d4] is the deuterium labelled 4-Bromo-α,α,α-trifluorotoluene. Group: Pharmaceutical. Alternative Names: 4-Bromo-α,α,α-trifluorotoluene D4; 4-Trifluoromethylbromobenzene-2,3,5,6-d4; 1-Bromo-4-(trifluoromethyl)benzene-d4; p-Bromo-α,α,α-trifluorotoluene-d4; 4-Bromo-1-(trifluoromethyl)benzene-d4; 4-Bromobenzotrifluoride-d4; p-(Trifluoromethyl)bromobenzene-d4; p-Bromobenzotrifluoride-d4. CAS No. 1219799-09-3. Pack Sizes: 5 g. Product ID: BLP-010532. Molecular formula: C7D4BrF3. Mole weight: 229.03. Custom synthesis is available. Send your inquiries for more information.
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4-Desmethyl-2-methyl Celecoxib
4-Desmethyl-2-methyl Celecoxib is an analog of Celecoxib, a cyclooxygenase 2 inhibitor. Group: Pharmaceutical. Alternative Names: 4-[5-(2-Methylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide; Celecoxib 2-Methyl Analog; 4-(5-o-Tolyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide. CAS No. 170569-99-0. Pack Sizes: 100 mg. Product ID: B2694-468625. Molecular formula: C17H14F3N3O2S. Mole weight: 381.38. Custom synthesis is available. Send your inquiries for more information.
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5,6-trans-Travoprost
One of the impurities of Travoprost, which has been found to be a selective FP prostaglandin receptor agonist and could be used against glaucoma. Group: Pharmaceutical. Alternative Names: Travoprost 5,6-trans isomer; (5E)-7-[(1R,3R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic Acid 1-Methylethyl Ester; Isopropyl (E)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate. CAS No. 1563176-59-9. Pack Sizes: 10 mg. Product ID: B1370-290009. Molecular formula: C26H35F3O6. Mole weight: 500.56. Custom synthesis is available. Send your inquiries for more information.
London
A01
A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM), which attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Study showed that it potentiated BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells. Group: Pharmaceutical. Alternative Names: Smurf1-IN-A01; Smurf1INA01; Smurf1 IN A01; Smurf1 inhibitor A01; Smurf1-inhibitor-A01; A01; A 01; A-01; [4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone; SMURF1 inhibitor A01. CAS No. 1007647-73-5. Pack Sizes: 1mg;1g;10g. Product ID: 1007647-73-5. Molecular formula: C22H20ClF3N4O3S. Mole weight: 512.93. Custom synthesis is available. Send your inquiries for more information.
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A 1070722
A 1070722 is a potent glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 0.6 nM for GSK-3α and GSK-3β) with 50-fold selectivity over other protein kinases such as CDK. It decreases phosphorylation of microtubule-associated protein Tau in vitro. A 1070722 exhibits neuroprotective activity thus is identified as a therapeutic drug candidate for neurodegenerative and psychiatric disorders. Uses: Potential treatment of neurodegenerative disorders. Group: Pharmaceutical. Alternative Names: A 1070722; A1070722; A-1070722; 1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea. CAS No. 1384424-80-9. Pack Sizes: 1mg;1g;10g. Product ID: 1384424-80-9. Molecular formula: C17H13F3N4O2. Mole weight: 362.31. Custom synthesis is available. Send your inquiries for more information.
London
A 1120
A 1120 is a retinol-binding protein 4 (RBP4) antagonist (Ki = 8.3 nM) that can reduce serum RBP4 and retinol, and displaces transthyretin (TTR) from RBP4-TTR complexes. Group: Pharmaceutical. Alternative Names: A-1120; A1120; 2-(4-(2-(Trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid. CAS No. 1152782-19-8. Pack Sizes: 100 mg. Product ID: B1370-271974. Molecular formula: C20H19F3N2O3. Mole weight: 392.37. Custom synthesis is available. Send your inquiries for more information.
London
A 425619
A 425619 is a potent and selective TRPV1 antagonist (IC50 = 3-9 nM) that inhibits TRPV1 activation by anandamide and N-arachidonoyl-dopamine. A 425619 exhibits an inhibitory effect against inflammatory, postoperative and osteoarthritic in vivo pain models. Uses: Analgesic. Group: Pharmaceutical. Alternative Names: A-425619; A 425619; A425619; N-5-Isoquinolinyl-N'-[[(4-(trifluoromethyl)phenyl]methyl]urea. CAS No. 581809-67-8. Pack Sizes: 1mg;1g;10g. Product ID: 581809-67-8. Molecular formula: C18H14F3N3O. Mole weight: 345.32. Custom synthesis is available. Send your inquiries for more information.
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A 437203
A 437203 is a selective dopamine (DA) D3 receptor antagonist suited to evaluate the physiological role(s) of D3 receptors. A 437203 shows an approximately 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors. Group: Pharmaceutical. Alternative Names: 2-[3-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]propylsulfanyl]-1H-pyrimidin-6-one; 2-(3-(4-(2-tert-butyl-6-trifluoromethylpyrimidin-4-yl)piperazin-1-yl)propylsulfanyl)-3H-pyrimidin-4-one fumarate; A 437203; A-437203; A437203; 1160247-85-7; 220519-07-3 (anhydrous); 220519-06-2 (anhydrous free base). CAS No. 220519-06-2. Pack Sizes: 1mg;1g;10g. Product ID: 220519-06-2. Molecular formula: C20H27F3N6OS. Mole weight: 456.53. Custom synthesis is available. Send your inquiries for more information.
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A 784168
A 784168 is a potent and selective TRPV1 antagonist (IC50 = 25 nM for inhibition of TRPV1 activation by 50 nM capsaicin) exhibiting no activity against a range of receptors such as TRPA1, GABA, opioid, and purinergic receptors. Group: Pharmaceutical. Alternative Names: A 784168; A784168; A-784168; 3,6-Dihydro-3'-(trifluoromethyl)-N-[4-[(trifluoromethyl)sulfonyl]phenyl]-[1(2H),2'-bipyridine]-4-carboxamide; 1-[3-(trifluoromethyl)pyridin-2-yl]-N-[4-(trifluoromethylsulfonyl)phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide. CAS No. 824982-41-4. Pack Sizes: 1mg;1g;10g. Product ID: 824982-41-4. Molecular formula: C19H15F6N3O3S. Mole weight: 479.4. Custom synthesis is available. Send your inquiries for more information.
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A-9758
A-9758 is an RORγ ligand and a potent and selective RORγt inverse agonist (IC50 = 5 nM), and shows strong potency against IL-17A release. A-9758 can effectively inhibit Th17 differentiation and Th17 effector function. A-9758 significantly attenuates IL-23 driven psoriasiform dermatitis and effectively blocks skin and joint inflammation. Group: Pharmaceutical. Alternative Names: 4-Piperidinecarboxylic acid, 1-[2,4-dichloro-3-[[1,4-dimethyl-6-(trifluoromethyl)-1H-indol-2-yl]methyl]benzoyl]-; 1-(2,4-Dichloro-3-{[1,4-dimethyl-6-(trifluoromethyl)-1H-indol-2-yl]methyl}benzoyl)-4-piperidinecarboxylic acid. CAS No. 2055271-22-0. Pack Sizes: 1mg;1g;10g. Product ID: 2055271-22-0. Molecular formula: C25H23Cl2F3N2O3. Mole weight: 527.36. Custom synthesis is available. Send your inquiries for more information.
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AACOCF
AACOCF, an anlogue of arachidonic acid, is a slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2. It also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Group: Pharmaceutical. Alternative Names: 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-heneicosateraen-2-one; Arachidonyl trifluoromethyl ketone; Arachidonyltrifluoromethane. CAS No. 149301-79-1. Pack Sizes: 1mg;1g;10g. Product ID: 149301-79-1. Molecular formula: C21H31F3O. Mole weight: 356.47. Custom synthesis is available. Send your inquiries for more information.
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AAL-993
AAL-993 is a VEGFR tyrosine kinase inhibitor that possesses dual inhibition of VEGFR signaling and HIF-1α expression through ERK inhibition without affecting Akt phosphorylation. Group: Pharmaceutical. Alternative Names: AAL 993; AAL993; 2-((4-pyridyl)methyl)amino-N-(3-(trifluoromethyl)phenyl)benzamide. CAS No. 269390-77-4. Pack Sizes: 1mg;1g;10g. Product ID: 269390-77-4. Molecular formula: C20H16F3N3O. Mole weight: 371.36. Custom synthesis is available. Send your inquiries for more information.
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ABT116
ABT116 is an antagonist of transient receptor potential vanilloid type 1. Group: Pharmaceutical. Alternative Names: ABT-116; ABT 116; ABT116; 1-[[2-(3,3-dimethylbutyl)-4-(trifluoromethyl)phenyl]methyl]-3-(1-methylindazol-4-yl)urea. CAS No. 1008529-42-7. Pack Sizes: 1mg;1g;10g. Product ID: 1008529-42-7. Molecular formula: C23H27F3N4O. Mole weight: 432.49. Custom synthesis is available. Send your inquiries for more information.
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ABT 925 Fumerate
A 437203 is a selective dopamine (DA) D3 receptor antagonist suited to evaluate the physiological role(s) of D3 receptors. A 437203 shows an approximately 100-fold higher in vitro affinity for dopamine D3 versus D2 receptors. Group: Pharmaceutical. Alternative Names: (E)-but-2-enedioic acid;2-[3-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]propylsulfanyl]-1H-pyrimidin-6-one; UNII-DMH23OL273; 220519-07-3 (anhydrous); 220519-06-2 (anhydrous free base); ABT-925 anhydrous; ABT 925 Fumerate; ABT925 Fumerate; ABT-925 Fumerate. CAS No. 220519-07-3. Pack Sizes: 1mg;1g;10g. Product ID: 220519-07-3. Molecular formula: C24H31F3N6O5S. Mole weight: 572.604. Custom synthesis is available. Send your inquiries for more information.
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ABX-1431
ABX-1431 is an inhibitor of monoacylglycerol lipase (MAGL; IC50s = 14 and 27 nM for human and rat enzyme, respectively). Group: Pharmaceutical. Alternative Names: 1,1,1,3,3,3-hexafluoropropan-2-yl 4-[[2-pyrrolidin-1-yl-4-(trifluoromethyl)phenyl]methyl]piperazine-1-carboxylate. CAS No. 1446817-84-0. Pack Sizes: 1mg;1g;10g. Product ID: 1446817-84-0. Molecular formula: C20H22F9N3O2. Mole weight: 507.3. Custom synthesis is available. Send your inquiries for more information.
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AC 4
AC 4 is a photoswitchable TRPV1 channel blocker (IC50 = 3.1 μM) that converts TRPV1 channels into photoreceptors. Group: Pharmaceutical. Alternative Names: AC 4; AC4; AC-4; 1,3,4,5-Tetrahydro-7,8-dihydro-N-[2-[4-[2-[4-(trifluoromethyl)phenyl]diazenyl]phenyl]ethyl]-2H-2-benzazepine-2-carbothioamide. CAS No. 1459809-09-6. Pack Sizes: 1mg;1g;10g. Product ID: 1459809-09-6. Molecular formula: C26H25F3N4O2S. Mole weight: 514.56. Custom synthesis is available. Send your inquiries for more information.
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Acrinathrin
Acrinathrin is a pyrethroid insecticide and acaricide with high efficiency, low toxicity and broad spectrum. Group: Pharmaceutical. Alternative Names: (1R,3S)-2,2-Dimethyl-3-[(1Z)-3-oxo-3-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-1-propenyl]cyclopropanecarboxylic Acid (S)-Cyano(3-phenoxyphenyl)methyl Ester; [1R-[1α(S*),3α(Z)]]-2,2-Dimethyl-3-[3-oxo-3-[2,2,2-trifluoro-1-(trifluoromethyl)ethoxy]-1-propenyl]cyclopropanecarboxylic Acid Cyano(3-phenoxyphenyl)methyl Ester; ACR 50 (pesticide); Ardent; HOE 076003; NU 702; Orytis; RU 38702; Rufast; (S)-α-cyano-3-phenoxybenzyl (Z)-(1R)-cis-2,2-dimethyl-3-[2-(2,2,2-trifluoro-1-trifluoromethylethoxycarbonyl)vinyl]cyclopropanecarboxylate; azrinathrin. CAS No. 101007-06-1. Pack Sizes: 1mg;1g;10g. Product ID: 101007-06-1. Molecular formula: C26H21F6NO5. Mole weight: 541.44. Custom synthesis is available. Send your inquiries for more information.
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Ac-WEHD-AFC
Ac-WEHD-AFC is a fluorogenic substrate for group I caspases including caspase-1, -4, and -5. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm. Group: Pharmaceutical. Alternative Names: Caspase 1 (ICE) Substrate 3f; fluorogenic, Ac-WEHD-AFC; N-Acetyl-L-tryptophyl-L-alpha-glutamyl-L-histidyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine; N-Acetyl-Trp-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin trifluoroacetate salt. CAS No. 210344-99-3. Pack Sizes: 50 mg. Product ID: BAT-010219. Molecular formula: C38H37F3N8O11. Mole weight: 838.7. Custom synthesis is available. Send your inquiries for more information.
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Afoxolaner
Afoxolaner is a potent isoxazoline insecticide and acaricide against Ixodes scapularis in dogs. It is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations in dogs and puppies. It is administered orally in meat-flavoured tablets, and poisons fleas once they start feeding. It is used either alone or as a combination treatment with milbemycin oxime. Group: Pharmaceutical. Alternative Names: 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide; 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]naphthalene-1-carboxamide. CAS No. 1093861-60-9. Pack Sizes: 100 mg. Product ID: B2692-475054. Molecular formula: C26H17ClF9N3O3. Mole weight: 625.87. Custom synthesis is available. Send your inquiries for more information.
London
α-Amyloid Precursor Protein Modulator
α-Amyloid Precursor Protein Modulator is a cell-permeable protein kinase C (PKC) activator. It was shown to induce differentiation of hESCs into Pdx-1 expressing pancreatic progenitor cells. Group: Pharmaceutical. Alternative Names: TPPB; alpha-APP Modulator; (2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dienamide. CAS No. 497259-23-1. Pack Sizes: 2.5 mg. Product ID: B0084-314011. Molecular formula: C27H30F3N3O3. Mole weight: 501.55. Custom synthesis is available. Send your inquiries for more information.
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Aprepitant
Aprepitant is a specific NK-1R antagonist, used as an antiemetic agent. Group: Pharmaceutical. Alternative Names: 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-triazol-3-one; Emend; L 754030; MK 0869; MK 869; ONO 7436. CAS No. 170729-80-3. Pack Sizes: 1 g. Product ID: B2692-461949. Molecular formula: C23H21F7N4O3. Mole weight: 534.43. Custom synthesis is available. Send your inquiries for more information.
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Autotaxin modulator 1
Autotaxin modulator 1 is a novel Autotaxin modulator. Group: Pharmaceutical. Alternative Names: 8-[(1R)-1-[8-(trifluoromethyl)-7-[4-(trifluoromethyl)cyclohexyl]oxynaphthalen-2-yl]ethyl]-8-azabicyclo[3.2.1]octane-3-carboxylic acidAutotaxin modulator 1; SCHEMBL15559445; SCHEMBL16934494; CS-4200; CS 4200; CS4200. CAS No. 1548743-69-6. Pack Sizes: 1mg;1g;10g. Product ID: 1548743-69-6. Molecular formula: C28H31F6NO3. Mole weight: 543.54. Custom synthesis is available. Send your inquiries for more information.
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AZD3965
AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, which is 6-fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Both lactate transport and cell growth are potently inhibited by AZD3965 in lymphoma cell lines that preferentially express MCT1. Lactate transport inhibition in some cell lines also induces a cytotoxic effect. In vitro combination studies show that lactate transport inhibition can enhance the induction of cell death by doxorubicin. Blocking lactate transport in vitro also leads to a rapid inhibition of glucose uptake in the Raji Burkitt's lymphoma cell line. In vivo, AZD3965 is well tolerated and induces a dose- and time-dependent accumulation of lactate in the tumors, suppresses tumor growth and in the Raji model potentiates the effects of Rituxan, doxorubicin and bendamustine. The selective inhibition of lactate transport by the MCT1 inhibitor AZD3965 offers a novel mechanism for targeting the metabolic phenotype in tumors that preferentially express MCT1. Group: Pharmaceutical. Alternative Names: (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; AZD3965; AZD-3965; AZD 3965. CAS No. 1448671-31-5. Pack Sizes: 25 mg. Product ID: B2693-463251. Molecular formula: C21H24F3N5O5S. Mole weight: 515.51. Custom synthesis is available. Send
London
BAY-876
BAY-876 is a potent and selective inhibitor of GLUT1, which is overexpressed in multiple cancers. Uses: Anticancer agent. Group: Pharmaceutical. Alternative Names: BAY-876; BAY 876; BAY876. 4-N-[1-[(4-cyanophenyl)methyl]-5-methyl-3-(trifluoromethyl)pyrazol-4-yl]-7-fluoroquinoline-2,4-dicarboxamide. CAS No. 1799753-84-6. Pack Sizes: 100 mg. Product ID: B0084-053992. Molecular formula: C24H16F4N6O2. Mole weight: 496.426. Custom synthesis is available. Send your inquiries for more information.
London
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