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| Product | Description | |
|---|---|---|
| Treosulfan | Treosulfan is the prodrug of a bifunctional sulfonate alkylating agent with myeloablative, immunosuppresive, and antineoplastic activities. Under physiological conditions, treosulfan converts nonenzymatically to L-diepoxybutane via a monoepoxide intermediate. The monoepoxide intermediate and L-diepoxybutane alkylate DNA at guanine residues and produce DNA interstrand crosslinks, resulting in DNA fragmentation and apoptosis. In escalated doses, this agent also exhbits myeloablative and immunosuppressive activities. Group: Pharmaceutical. Alternative Names: NSC 39069; NSC39069; NSC-39069; Treosulfan; (2S,3S)-2,3-Dihydroxybutane-1,4-diyl dimethanesulfonate. CAS No. 299-75-2. Pack Sizes: 25 mg. Product ID: B2693-065470. Molecular formula: C6H14O8S2. Mole weight: 278.29. Custom synthesis is available. Send your inquiries for more information. |  London |
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