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| Product | Description | |
|---|---|---|
| 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-galactopyranosyl-Fmoc serine | 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-galactopyranosyl-Fmoc serine, renowned as an indispensible glycosylated amino acid, is commonly utilized during the manufacture of peptides and glycopeptide antibiotics. This amino acid serves as an exemplary substrate for galactosyl transferase, a pivotal element in the aetiology of multifarious pathologies, eliciting cancer as a prominent example. Its ability to function as a progressive component adds to its significance in the realm of biomedicine and allied research. Group: Pharmaceutical. CAS No. 120173-57-1. Pack Sizes: 25 mg. Product ID: BAT-008015. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 3-Deazaneplanocin A | 3-Deazaneplanocin A is an inhibitor of S-adenosylmethionine-dependent methyltransferase. In combination with sodium butyrate, 3-Deazaneplanocin A can induce epigenetically reprogramming of human embryonic stem cells (hESC). Group: Pharmaceutical. CAS No. 102052-95-9. Pack Sizes: 10 mg. Product ID: B0084-462897. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-366 | A-366 is a peptide-competitive inhibitor of the G9a/GLP histone lysine methyltransferase (IC50 = 3.3 nM) and is approximately 1000-fold selective over other methyltransferases. Group: Pharmaceutical. CAS No. 1527503-11-2. Pack Sizes: 100 mg. Product ID: B2693-474604. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A-485 | A-485 is an inhibitor of the histone acetyltransferase p300/CBP (IC50 = 60 nM). Group: Pharmaceutical. CAS No. 1889279-16-6. Pack Sizes: 100 mg. Product ID: B1370-292260. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A 58365 A | A58365 A is an enzyme inhibitor produced by Streptomyces chromofuscus A58365.1. It has the effect of inhibiting angiotensin transferase (ACE). Group: Pharmaceutical. CAS No. 87896-52-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03161. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A 58365 B | A58365 B is an enzyme inhibitor produced by Streptomyces chromofuscus A58365.1. It has the effect of inhibiting angiotensin transferase (ACE). Group: Pharmaceutical. CAS No. 87896-53-5. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03162. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acivicin | Acivicin is an isoxazole antibiotic isolated from Streptomyces. sviceus. Acivicin is a glutamine analog that irreversibly inhibits glutamine-dependent amidotransferases involved in nucleotide and amino acid biosynthesis (Kis = 10 and 560 μM for anthranilate synthase and glutamate synthase, respectively) as a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. Acivicin is an inhibitor of GGT used for solid tumor research. Uses: Protease inhibitor. Group: Pharmaceutical. CAS No. 42228-92-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-00541. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AMI-1 | AMI-1 is a cell-permeable inhibitor which inhibits protein arginine N-methyltransferase (PRMT) activity with IC50 of 8.81 μM for PRMT1 and IC50 of 3.04 μM for Hmt1p in vitro. MI-1 does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site and exhibits minimal effects on both SET (Sub39H1, Suv39H2, SET7) and non-SET (DOT1) lysine N-methyltransferases. Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. Group: Pharmaceutical. CAS No. 20324-87-2. Pack Sizes: 50 mg. Product ID: B2693-087022. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bakuchiol | Bakuchiol is a phytoestrogen isolated from the seeds of Psoralea corylifolia L with anti-tumor, antioxidant, and antibacterial effects. Bakuchiol has a retinol-like effect on skin gene expression and properties. Bakuchiol inhibits DNA polymerase and UDP-glucuronosyltransferase 2B7 (IC50 = 41 μM). Bakuchiol has hypoglycemic, hypolipidemic, anti-inflammatory, anti-wrinkle, soothing and liver protective, anticancer, antidepressant, and estrogen-like effects. Uses: Antioxidant. Group: Pharmaceutical. CAS No. 10309-37-2. Pack Sizes: 100 mg. Product ID: NP4619. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bendamustine hydrochloride | Bendamustine hydrochloride is the hydrochloride salt of bendamustine, a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and protein synthesis inhibition, and, subsequently, apoptosis. Bendamustine may differ from other alkylators in that it may be more potent in activating p53-dependent stress pathways and inducing apoptosis; it may induce mitotic catastrophe; and it may activate a base excision DNA repair pathway rather than an alkyltransferase DNA repair mechanism. Group: Pharmaceutical. CAS No. 3543-75-7. Pack Sizes: 500 mg. Product ID: NP3323. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Blumeatin | Blumeatin is found in tea and is extracted from the herbs of Blumea balsamifera. It can enhance adipocyte differentiation by increasing triglyceride levels in 3T3L1 cells. It also can increase the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes GLUT4 and aP2. It inhibits the increase of liver triglyceride and serum alanine aminotransferase, and increases serum beta-lipoprotein, liver glycogen and triglyceride content in CCl4-intoxicated rats, thus shorten the pentobarbital sleeping time in CCl4-intoxicated mice. It shows free radical scavenging activity, xanthine oxidase (XO) inhibitory activity and antioxidant properties. It can protect liver against injury induced by CCl4 and TAA. Group: Pharmaceutical. CAS No. 118024-26-3. Pack Sizes: 10 mg. Product ID: B1370-267733. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| C646 | C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other acetyltransferases. Group: Pharmaceutical. CAS No. 328968-36-1. Pack Sizes: 25 mg. Product ID: B0084-370250. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CP-609754 | CP-609754, also known as CP-609,754,LNK 754 and OSI 754, is a potent arnesyltransferase inhibitor with potential anticancer activity. Group: Pharmaceutical. CAS No. 1190094-64-4. Pack Sizes: 100 mg. Product ID: B2693-462491. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Deoxynivalenol | Deoxynivalenol is a type B trichothecene, an epoxy-sesquiterpenoid. This mycotoxin can induce vomiting, diarrhea, and weight loss as well as other physiological and toxicological effects. It inhibits protein biosynthesis, binds to peptidyl transferase, and inhibits the synthesis of RNA and DNA, contributing to immunotoxicity. Group: Pharmaceutical. CAS No. 51481-10-8. Pack Sizes: 5 mg. Product ID: BBF-01828. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Entacapone | Entacapone is a selective and reversible inhibitor of the enzyme catechol-O-methyltransferase (COMT) (IC50 = 151 nM), commonly used in combination with other medications for the treatment of Parkinson's disease. Group: Pharmaceutical. CAS No. 130929-57-6. Pack Sizes: 500 mg. Product ID: B0084-057038. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| EPZ015866 | EPZ015866,also called as GSK591, is a chemical probe for PRMT5 which has a role in diverse cellular processes including tumorigenesis. It exhibits excellent selectivity against a panel of methyltransferases. Inhibits the PRMT5/MEP50 complex from methylati. Group: Pharmaceutical. CAS No. 1616391-87-7. Pack Sizes: 300 mg. Product ID: B0084-474632. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ezatiostat | Ezatiostat is a glutathione analog that acts as an inhibitor of glutathione S-transferase (GST) P1-1. TLK117, the active form of ezatiostat, inhibits GSTP1-1, resulting in phosphorylation of JNK, restoring JNK-mediated cellular proliferation and differentiation signaling pathways. Group: Pharmaceutical. CAS No. 168682-53-9. Pack Sizes: 25 mg. Product ID: BAT-010079. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| FK866 | FK866 is a non-competitive inhibitor of nicotinamide phosphoribosyltransferase (Nampt) with potential antineoplastic and antiangiogenic activities. FK866 binds to Nampt to suppress the biosynthesis of nicotinamide adenine dinucleotide (NAD+), leading to tumor cell apoptosis. Uses: Potential anticancer agent. Group: Pharmaceutical. CAS No. 658084-64-1. Pack Sizes: 50 mg. Product ID: B0084-377502. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDP-L-fucose disodium salt | Substrate for fucosyltransferase. Group: Pharmaceutical. CAS No. 148296-47-3. Pack Sizes: 5 mg. Product ID: B2706-339907. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GGTI-2418 | GGTI-2418 is a synthetic peptidomimetic inhibitor of geranylgeranyltransferase I (GGTase I) that appears to induce apoptosis by downregulating several pivotal oncogenic and tumor survival pathways. GGTase I catalyzes the lipid posttranslational modification which is required for the function of Rho GTPases (frequently found aberrantly activated in human cancer). GGTase I inhibitors block Rho function in cancer cells and induce a G1 phase cell cycle arrest by a mechanism involving induction of the CDK inhibitors p21waf and p27kip, CDK2 and CDK4 inhibition and hypophoshorylation of the tumor suppressor Rb. GGTase I inhibitors also induce apoptosis by a mechanism involving downregulation of the expression of survivin and suppression of the activation of PI3K/Akt. Group: Pharmaceutical. CAS No. 501010-06-6. Pack Sizes: 2.5 mg. Product ID: B0084-462530. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GGTI-298 | GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-298 causes G0-G1 cell cycle block and apoptosis in A549 cells (IC50 = 10 μM for A549 cells) and inhibits cell invasion and migration in COLO 320CM cells. Group: Pharmaceutical. CAS No. 180977-44-0. Pack Sizes: 5 mg. Product ID: B0084-272121. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GSK3326595 | GSK3326595, also called as EPZ015938, is an orally available and specific inhibitor of protein arginine methyltransferase 5 (PRMT5) that potently inhibits tumor growth in vitro and in vivo in animal models and has entered clinical trials for the treatment of solid tumors and non-Hodgkin's lymphoma. Group: Pharmaceutical. CAS No. 1616392-22-3. Pack Sizes: 100 mg. Product ID: B2693-007330. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Homovanillic Acid-[d3] | Homovanillic Acid-[d3] is an isotopically-labeled version of Homovanillic Acid (HVA). This important dopamine metabolite is predominantly found in human urine and is a valuable biochemical research tool for investigating the mechanisms underlying neuropsychiatric and neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, and schizophrenia. Its use in these studies is useful, given the marked alterations in dopamine metabolism and function that are observed in these conditions. Uses: A neuroendocrine tumor marker. a labelled metabolite of dihydroxyphenylacetic acid (dopac) by catechol o-methyltransferase. Group: Pharmaceutical. CAS No. 74495-71-9. Pack Sizes: 10 mg. Product ID: BLP-011889. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Inobrodib | Inobrodib is an inhibitor of the histone acetyltransferase p300 and CREB-binding protein and has antineoplastic activity. Group: Pharmaceutical. CAS No. 2222941-37-7. Pack Sizes: 5 mg. Product ID: B2693-373001. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lanreotide | Laromustine is a sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE chloroethylates alkylates the 06 position of guanine, resulting in DNA crosslinking, strand breaks, chromosomal aberrations, and disruption of DNA synthesis. Intracellular metabolism of this agent also releases methyl isocyanate which inhibits 06-alkyl-guanine transferase, an enzyme involved with DNA repair. Group: Pharmaceutical. CAS No. 108736-35-2. Pack Sizes: 25 mg. Product ID: BAT-010202. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lomeguatrib | Lomeguatrib, also known as PaTrin-2, is a potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase. Lomeguatrib is also a nontoxic low-molecular weight pseudosubstrate that has the ability to inactivate MGMT. Lomeguatrib can be used with temozolomide (TMZ) for GBM treatment. Group: Pharmaceutical. CAS No. 192441-08-0. Pack Sizes: 100 mg. Product ID: B0084-086622. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lonafarnib | Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. Uses: Enzyme inhibitors. Group: Pharmaceutical. CAS No. 193275-84-2. Pack Sizes: 25 mg. Product ID: B2693-086642. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| LS-tetrasaccharide c | LS-tetrasaccharide c is an extraordinary biomedical compound, bestowed with the exceptional ability to impede ceramide glycosyltransferase, a vital actor implicated in the relentless march of tumor propagation and metastasis. Group: Pharmaceutical. CAS No. 64003-55-0. Pack Sizes: 5 mg. Product ID: B1370-407252. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| L-Vinylglycine | L-Vinylglycine is a non-proteinogenic L-alpha-amino acid and an inhibitor of aspartate aminotransferase. Group: Pharmaceutical. CAS No. 70982-53-5. Pack Sizes: 100 mg. Product ID: B0084-335459. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MAK683 | MAK683 is an inhibitor of embryonic ectoderm development protein (EED) with potential antineoplastic activity. MAK683 binds to the domain of EED that interacts with trimethylated lysine 27 on histone 3 (H3K27me3), leading to a conformational change in the EED H3K27me3-binding pocket and preventing the interaction of EED with the histone methyltransferase enhancer zeste homolog 2 (EZH2). MAK683 is undergoing phase II clinical trials for the identification of antitumor activity. Group: Pharmaceutical. CAS No. 1951408-58-4. Pack Sizes: 5 mg. Product ID: B0084-008118. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Methotrexate EP Impurity L | An impurity of Methotrexate, an antimetabolite and immunosuppressant used in chemotherapy and auto-immune diseases. This impurity also acts as an inhibitor of human DNA methyltransferase. Group: Pharmaceutical. CAS No. 52980-68-4. Pack Sizes: 100 mg. Product ID: B2694-438505. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Methyl b-D-glucuronide sodium salt | Methyl b-D-glucuronide sodium salt is a chemical compound used in the biomedical industry for its role in drug metabolism studies. It is commonly employed as a substrate to evaluate glucuronidation reactions mediated by glucuronosyltransferase enzymes. This product aids in understanding drug metabolism and its implications in treating various diseases by facilitating the study of drug elimination pathways. Group: Pharmaceutical. CAS No. 134253-42-2. Pack Sizes: 5 g. Product ID: B2705-209389. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MS023 | MS023 is a Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases. MS023 displayed high potency for type I PRMTs including PRMT1, -3, -4, -6, and -8 but was completely inactive against type II and type III PRMTs, protein lysine methyltransferases and DNA methyltransferases. Group: Pharmaceutical. CAS No. 1831110-54-3. Pack Sizes: 300 mg. Product ID: B0084-470903. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MS023 dihydrochloride | MS023 dihydrochloride is a potent, selective and cell-active human type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively. Group: Pharmaceutical. CAS No. 1992047-64-9. Pack Sizes: 100 mg. Product ID: B1370-382055. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-(4-Nitrophenyl)-L-glutamine | N-(4-Nitrophenyl)-L-glutamine is a substrate for γ-glutamyltransferase (GGT), which is an important enzyme with wide applications in biocatalysis and clinical diagnosis. Group: Pharmaceutical. CAS No. 7300-59-6. Pack Sizes: 100 g. Product ID: BAT-002168. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-acetyl-D-glucosamine-[UL-13C6] | N-acetyl-D-glucosamine-[UL-13C6] is the labelled analogue of N-Acetyl-D-glucosamine, which is an acceptor substrate for galactosyltransferases. When added to the medium, it improves the recovery of Haemophilus influenza from sputum. It is a competitive inhibitor of β-N-acetylhexosaminidase. Group: Pharmaceutical. CAS No. 1194446-34-8. Pack Sizes: 50 mg. Product ID: BLP-008503. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Boc-1,2,3,6-tetrahydropyridine-4-boronic Acid Pinacol Ester | Reagent used for : Suzuki-Miyaura cross-coupling using palladium phosphine catalyst ; Palladium-catalyzed ligand-controlled regioselective Suzuki coupling ; Palladium-catalyzed Suzuki-Miyaura coupling ; Suzuki coupling followed by iodolactonization reaction ; Wrenchnolol derivative optimized for gene activation in cells Reagent used in Preparation of several enzymatic inhibitors and receptor ligands; Orally active anaplastic lymphoma kinase inhibitors ; Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes ; 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cyclopropanecarboxamides as novel melatonin receptor ligands ; Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder ; Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists. Group: Pharmaceutical. CAS No. 286961-14-6. Pack Sizes: 100 g. Product ID: BB019917. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Opicapone | Opicapone is a long-acting, peripherally selective inhibitor of catechol-O-methyltransferase. Group: Pharmaceutical. CAS No. 923287-50-7. Pack Sizes: 10 mg. Product ID: B2693-460564. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| P21 Peptide acetate | P21 Peptide has the effect of inhibiting protein transferase. Group: Pharmaceutical. Pack Sizes: 100 mg. Product ID: BAT-009965. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Phenyl 4-O-acetyl-2,6-Di-O-benzoyl-1-thio-beta-thio-beta-D-galactopyranoside | Phenyl 4-O-acetyl-2,6-Di-O-benzoyl-1-thio-beta-thio-beta-D-galactopyranoside is a compound, exhibiting its paramount significance in delving deep into the enigmatic realms of glycosylation processes and the enthralling world of carbohydrate chemistry. It effortlessly assumes the dual roles of an eminent substrate in an immense array of biochemical assays, particularly those centered around the captivating realms of glycosyltransferases, glycosidases and various other riveting carbohydrate enzymes. Group: Pharmaceutical. CAS No. 152488-28-3. Pack Sizes: 1 g. Product ID: B1370-204821. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Raltegravir Potassium Salt | Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM). It is metabolized primarily by uridine diphosphate glucuronosyltransferase 1A. Raltegravir has long-term efficacy and safety in managing HIV-1 infection in adults, children, and adolescents. Uses: Anti-hiv agents. Group: Pharmaceutical. CAS No. 871038-72-1. Pack Sizes: 1 g. Product ID: B2692-078687. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| RG108 | RG108 is a DNA methyltransferase inhibitor with IC50 value of 115 nM. RG108 can enhance reprogramming of somatic cells to induced pluripotent stem (iPS) cells. Group: Pharmaceutical. CAS No. 48208-26-0. Pack Sizes: 250 mg. Product ID: B0084-462912. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| RTA-408 | RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Group: Pharmaceutical. CAS No. 1474034-05-3. Pack Sizes: 20 mg. Product ID: B0084-462776. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Schisanhenol | Schisanhenol has antioxidative effect on human LDL oxidation. The mechanism of Schisanhenol against LDL oxidation may be through scavenging free radicals. Uses: Ugt2b7 udp-glucuronosyltransferases inhibitor. Group: Pharmaceutical. CAS No. 69363-14-0. Pack Sizes: 20 mg. Product ID: NP4122. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sedanolide | Sedanolide is a natural phthalide compound originally isolated from seed oil of the Umbelliferae family, including celery. It is an inducer of glutathione S-transferase and inhibitor of chemically induced carcinogenesis. Group: Pharmaceutical. CAS No. 6415-59-4. Pack Sizes: 10 mg. Product ID: B1370-130717. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sulforaphane | Sulforaphaneis a naturally-occurring phytochemical belonging to the class of isothiocyanates. As the aglycone metabolite of glucosinolate glucoraphanin (sulforaphane glucosinolate), sulforaphane acts as an antioxidant and potent stimulator of endogenous detoxifying enzymes. This agent displays anticarcinogenic properties due to its ability to induce phase II detoxification enzymes, such as glutathione S-transferase and quinone reductase, thereby providing protection against certain carcinogens and toxic, reactive oxygen species. Broccoli sprouts contain large amounts of sulforaphane, which is also found in other cruciferous vegetables including cabbage and kale. Uses: Anti-inflammatory/antitumor. Group: Pharmaceutical. CAS No. 4478-93-7. Pack Sizes: 1 g. Product ID: NP4355. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| T863 | T-863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. It causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice. Group: Pharmaceutical. CAS No. 701232-20-4. Pack Sizes: 25 mg. Product ID: B2693-131149. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| TP 064 | TP 064 is a potent and selective PRMT4 inhibitor with >100-fold selectivity over other histone methyltransferases and non-epigenetic targets. TP 064 inhibits methylation of H3 (1-25) and MED12 in cellular assays (IC50 values are <10 and 43 nM, respectively). Group: Pharmaceutical. CAS No. 2080306-20-1. Pack Sizes: 25 mg. Product ID: B2693-170422. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-6-azido-6-deoxy-D-Gal | UDP-6-azido-6-deoxy-D-Gal, a nucleotide analog with great potential for studying glycosylation, has been employed in the synthesis of azido-sugars and labeling experiments to scrutinize the capabilities of glycosyltransferases. Its utility extends to probing the contribution of glycosylation in widespread pathological processes such as cancer and inflammation. This product can greatly benefit scientific research by providing precise and versatile tools to better understand glycosylation. Group: Pharmaceutical. CAS No. 868208-96-2. Pack Sizes: 1 mg. Product ID: B2706-383271. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-D-glucose disodium salt | UDP-D-glucose disodium salt is a phosphorylated uridine derivative used in nucleotide sugars metabolism as a substrate for the enzyme glucosyltransferases. It is used in the treatment of chronic alcoholism and in characterization of limonoid glucosyltransferase. Group: Pharmaceutical. CAS No. 28053-08-9. Pack Sizes: 1 g. Product ID: B1370-368748. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-D-glucuronide trisodium salt | UDP-D-glucuronide trisodium salt is a crucial compound used for drug metabolism studies. It acts as a donor molecule for the glucuronyl transferase enzyme, which helps in the biotransformation and detoxification of a wide range of drugs and endogenous compounds. This trisodium salt form facilitates stability and solubility, making it suitable for drug discovery and pharmacokinetic studies. Group: Pharmaceutical. CAS No. 63700-19-6. Pack Sizes: 250 mg. Product ID: B2706-146244. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-GalNAz disodium salt | UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor. Group: Pharmaceutical. CAS No. 653600-61-4. Pack Sizes: 10 mg. Product ID: B1370-071303. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| UDP-N-acetyl-D-galactosamine disodium salt | UDP-N-acetyl-D-galactosamine disodium salt is a nucleotide sugar used by glycosyltransferases to transfer N-acetylgalactosamine residues to substrates. Group: Pharmaceutical. CAS No. 108320-87-2. Pack Sizes: 100 mg. Product ID: B2706-358651. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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