Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| Tofacitinib | Tofacitinib is an orally available JAK3 inhibitor (IC50 = 1 nM), exhibiting 20- and 100-fold less potency against JAK2 and JAK1. Tofacitinib induces G1 cell cycle arrest and inhibits tumor growth in Epstein-Barr virus-associated T and natural killer cell lymphoma cells. It is approved for the treatment of rheumatoid arthritis (RA). Group: Pharmaceutical. Alternative Names: Tasocitinib; 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile; CP-690550. CAS No. 477600-75-2. Pack Sizes: 1 g. Product ID: B0084-453466. Molecular formula: C16H20N6O. Mole weight: 312.37. Custom synthesis is available. Send your inquiries for more information. |  London |
| Tofacitinib citrate | Tofacitinib (trade name Xeljanz, formerly tasocitinib, CP-690550) is a drug discovered and developed by Pfizer. It is currently approved for the treatment of rheumatoid arthritis (RA) in the United States and is being studied for treatment of psoriasis, inflammatory bowel disease, and other immunological diseases, as well as for the prevention of organ transplant rejection. (source: http://en.wikipedia.org/wiki/Tofacitinib). Uses: Janus kinase inhibitors. Group: Pharmaceutical. Alternative Names: CP-690550; CP 690550; CP690550; Tofacitinib; tasocitinib. CAS No. 540737-29-9. Pack Sizes: 500 mg. Product ID: NP2603. Molecular formula: C22H28N6O8. Mole weight: 504.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Tofacitinib N-Oxide | Tofacitinib N-Oxide is an impurity of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: Tofacitib related impuritie 8; 1-Piperidinepropanenitrile, 4-methyl-3-(methyloxido-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, (3R,4R)-. CAS No. 2028267-73-2. Pack Sizes: 50 mg. Product ID: B2694-006572. Molecular formula: C16H20N6O2. Mole weight: 328.37. Custom synthesis is available. Send your inquiries for more information. | London |
| (3R,4S)-Tofacitinib | (3R,4S)-Tofacitinib is a less active enantiopure stereoisomer of the JAK3 inhibitor Tofacitinib. Group: Pharmaceutical. Alternative Names: Tofacitinib Impurity A; 3-((3R,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile. CAS No. 1092578-46-5. Pack Sizes: 2.5 mg. Product ID: B2694-463514. Molecular formula: C16H20N6O. Mole weight: 312.27. Custom synthesis is available. Send your inquiries for more information. | London |
| (3S,4R)-Tofacitinib | (3S,4R)-Tofacitinib is a less active enantiopure stereoisomer of the JAK3 inhibitor Tofacitinib. Group: Pharmaceutical. Alternative Names: Tofacitinib Impurity B; 3-((3S,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile. CAS No. 1092578-48-7. Pack Sizes: 2.5 mg. Product ID: B2694-463516. Molecular formula: C16H20N6O. Mole weight: 312.27. Custom synthesis is available. Send your inquiries for more information. | London |
| (3S,4S)-Tofacitinib | (3S,4S)-Tofacitinib is a less active enantiopure stereoisomer of the JAK3 inhibitor Tofacitinib. Group: Pharmaceutical. Alternative Names: Tofacitinib Impurity C; 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile. CAS No. 1092578-47-6. Pack Sizes: 1 mg. Product ID: B2694-463515. Molecular formula: C16H20N6O. Mole weight: 312.27. Custom synthesis is available. Send your inquiries for more information. | London |
| Dihydro Tofacitinib Citrate | An impurity of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: Tofacitinib Impurity; 5,6-Dihydro CP-690550 citrate; 5,6-Dihydro Tofacitinib citrate. Pack Sizes: 25 mg. Product ID: B2694-342495. Molecular formula: C22H30N6O8. Mole weight: 506.51. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropanenitrile | One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: N-Methyl-N-(3R,4R)-1-cyanoacetyl-4-methylpiperidin-3-yl-2-chloro-7-deazapurine-6-amine; Tofacitinib Impurity 21. CAS No. 1616761-00-2. Pack Sizes: 25 mg. Product ID: B1370-379650. Molecular formula: C16H19ClN6O. Mole weight: 346.81. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-((3R,4R)-4-methyl-3-(methylamino)piperidin-1-yl)-3-oxopropanenitrile hydrochloride | An impurity of Tofacitinib, a Janus kinase inhibitor that could be used against rheumatoid arthritis. Group: Pharmaceutical. CAS No. 1640971-87-4. Pack Sizes: 5 mg. Product ID: B2694-063174. Molecular formula: C10H18ClN3O. Mole weight: 231.72. Custom synthesis is available. Send your inquiries for more information. | London |
| (3R,4R)-1-Benzyl-3-(methylamino)-4-methylpiperidine Dihydrochloride | (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Group: Pharmaceutical. Alternative Names: (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine;dihydrochloride; (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine;dihydrochloride. CAS No. 1062580-52-2. Pack Sizes: 100 g. Product ID: B2694-150044. Molecular formula: C14H24Cl2N2. Mole weight: 291.26. Custom synthesis is available. Send your inquiries for more information. | London |
| (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine | (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Group: Pharmaceutical. CAS No. 1638499-31-6. Pack Sizes: 50 mg. Product ID: B2694-080065. Molecular formula: C14H22N2. Mole weight: 218.34. Custom synthesis is available. Send your inquiries for more information. | London |
| (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine | (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Group: Pharmaceutical. Alternative Names: (3S,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine. CAS No. 1638499-33-8. Pack Sizes: 25 mg. Product ID: B2694-111800. Molecular formula: C14H22N2. Mole weight: 218.34. Custom synthesis is available. Send your inquiries for more information. | London |
| (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride | (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Group: Pharmaceutical. Alternative Names: Tofacitinib impurity G; Tofacitinib Impurity 02; cis-1-Benzyl-3-(methylamino)-4-methylpiperidine dihydrochloride. CAS No. 1354486-07-9. Pack Sizes: 5 g. Product ID: B2694-088366. Molecular formula: C14H24Cl2N2. Mole weight: 291.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Upadacitinib | Upadacitinib is a selective JAK inhibitor under the development of AbbVie.ABT-494 is nearly 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. Preliminary evidence suggests that ABT-494 may spare Jak2 and Jak3 dependent signaling compared to tofacitinib. Phase II for the treatment of Atopic dermatitis and Crohn's disease, Phase III for the treatment of Rheumatoid arthritis and Ulcerative colitis was on-going. Uses: Rheumatoid arthritis; ulcerative colitis;atopic dermatitis; crohn's disease. Group: Pharmaceutical. Alternative Names: UNII-4RA0KN46E0;ABT494;(3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide. CAS No. 1310726-60-3. Pack Sizes: 5 mg. Product ID: B0084-475295. Molecular formula: C17H19F3N6O. Mole weight: 380.37. Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
