Thyroid Suppliers UK

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Product
(14R)-paricalcitol (14R)-paricalcitol is an isomer of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B0075-054110. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
1α-Hydroxy VD4 1α-Hydroxy VD4 is an analogue of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Group: Pharmaceutical. CAS No. 143032-85-3. Pack Sizes: 1 mg. Product ID: B1959-054064. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
1β-doxercalciferol 1β-doxercalciferol is an isomer of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Group: Pharmaceutical. CAS No. 127516-23-8. Pack Sizes: 1 mg. Product ID: B1959-262189. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
1β-maxacalcitol 1β-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 169218-34-2. Pack Sizes: 5 mg. Product ID: B1128-054106. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
1β-trans-maxacalcitol 1β-trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B1128-054103. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(20R)-1β-maxacalcitol (20R)-1β-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 2 mg. Product ID: B1128-054099. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(20R)-1β-trans-maxacalcitol (20R)-1β-trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 2 mg. Product ID: B1128-054102. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(20R)-trans-maxacalcitol (20R)-trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: B1128-054096. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(20S)-paricalcitol (20S)-paricalcitol is an isomer of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B0075-054109. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(24R)-paricalcitol (24R)-paricalcitol is an isomer of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 132015-95-3. Pack Sizes: 5 mg. Product ID: B0075-054107. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
3,3,5-Triiodo-L-thyronine 3,3,5-Triiodo-L-thyronine is a metabolite of thyroxine that binds to both thyroid hormone receptors TRα and TRβ so that might help maintain the metabolic homeostasis. It promotes chondrogenesis of human mesenchymal stem cells. Uses: 3,3,5-triiodo-l-thyronine(t3) is an active metabolite of thyroxine and could be effective in agonizing both thyroid hormone receptors trα and tr&beta. Group: Pharmaceutical. CAS No. 6893-2-3. Pack Sizes: 1 g. Product ID: B0084-357278. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
3,3',5-Triiodo Thyropropionic Acid 3,3',5-Triiodo Thyropropionic Acid is a thyroid hormone analog that can be used as an antilipemic. Group: Pharmaceutical. CAS No. 51-26-3. Pack Sizes: 20 mg. Product ID: B0136-120818. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
3α-paricalcitol 3α-paricalcitol is an isomer of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 216161-87-4. Pack Sizes: 5 mg. Product ID: B0075-054116. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
A-75943 A-75943 is is a bone resorption inhibitor produced by Streptomyces sp. SANK61296. In vitro tests, it has the effect of inhibiting bone resorption with IC50 of 0.35 μmol/L. It also inhibits the bone resorption in rats with thyroid and parathyroidectomy. Group: Pharmaceutical. CAS No. 201215-10-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-03166. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Abaloparatide Abaloparatide is an analogue of parathyroid hormone-related protein (PTHrP) which is used for the treatment of osteoporosis. In 28 April 2017, it was approved by FDA for the treatment of postmenopausal women with osteoporosis. Studies showed that abaloparatide could decrease the risk of new vertebral and nonvertebral fractures. Uses: The treatment of osteoporosis. Group: Pharmaceutical. CAS No. 247062-33-5. Pack Sizes: 1 mg. Product ID: BAT-006119. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Abaloparatide acetate Abaloparatide acetate, an effective and selective activator of the PTHR1 signaling pathway, is an analog of parathyroid hormone-related protein (PTHrP) used for the treatment of osteoporosis. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016365. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Abaloparatide TFA Abaloparatide TFA is an analog of parathyroid hormone-related protein (PTHrP) used for the treatment of osteoporosis. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016324. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Agouti-related Protein (AGRP) (25-82), human Agouti-related protein (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It acts as a melanocortin receptor antagonist that exerts a central inhibitory action on the Hypothalamic-Pituitary-Thyroid (HPT) Axis. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BAT-006143. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Cabozantinib Impurities Cabozantinib Impurities are studied in the pharmaceutical industry for their roles in understanding the safety and efficacy of cabozantinib, a kinase inhibitor used in treating cancers like renal cell carcinoma and medullary thyroid carcinoma. Research on impurities is crucial for developing safer cancer therapeutics and ensuring drug purity. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Calcitonin eel Calcitonin eel is a peptide hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Group: Pharmaceutical. CAS No. 57014-02-5. Pack Sizes: 2.5 mg. Product ID: BAT-006141. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Calcitriol Impurities Calcitriol Impurities, integral in quality control, are key to assessing the purity of calcitriol formulations, crucial for treating conditions like osteoporosis, rickets, and hypoparathyroidism. These impurities help in fine-tuning drug efficacy and safety, ensuring that calcitriol-based therapies maintain optimal performance against bone-related disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Cholecalciferol EP Impurity A 5,6-trans-Vitamin D3 is the major photoisomer of Vitamin D3 analog. Vitamin D3 is a type of vitamin D found to be effective in mediating intestinal calcium absorbtion and bone calcium metabolism. Vitamin D3 is used for the prevention and treatment of vitamin D deficiency and associated disease including rickets, and also used for familial hypophosphatemia, hypoparathyroidism and Fanconi syndrome. Group: Pharmaceutical. CAS No. 22350-41-0. Pack Sizes: 50 mg. Product ID: B2694-468859. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Cinacalcet Impurities Cinacalcet Impurities serve as essential analytical standards, deeply embedded in the rigorous quality control and characterization processes of Cinacalcet. Integral to combating secondary hyperparathyroidism and parathyroid carcinoma, they necessitate precise impurity analysis to ensure safety, therapeutic efficacy, and compliance with regulatory parameters, vital in the pharmaceutical developmental trajectory. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Cinacalcet Impurity 18 An impurity of Cinacalcet, a medication used in the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 1020414-30-5. Pack Sizes: 100 mg. Product ID: B2694-468985. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Cinacalcet Impurity 7 An impurity of Cinacalcet, a medication used in the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 21172-43-0. Pack Sizes: 50 mg. Product ID: B2694-468971. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Cinacalcet Impurity B (HCl salt form) Cinacalcet Impurity B (HCl salt form) is an impurity of Cinacalcet, a medication used to treat secondary hyperparathyroidism in patients with chronic kidney disease and parathyroid carcinoma. Group: Pharmaceutical. CAS No. 163831-65-0. Pack Sizes: 50 mg. Product ID: B0041-237437. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Cinacalcet Impurity D N-[(3-Trifluoromethyl)phenyl)propyl] Cinacalcet is an impurity of Cinacalcet Hydrochloride. Cinacalcet is used in clinical trial in secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 1271930-15-4. Pack Sizes: 50 mg. Product ID: B0041-468972. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
ent-Cinacalcet Hydrochloride ent-Cinacalcet Hydrochloride is the (S) enantiomer of Cinacalcet. It is used in clinical trial in secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 694495-47-1. Pack Sizes: 25 mg. Product ID: B1370-468966. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Etelcalcetide hydrochloride Etelcalcetide is a calcium-sensing receptor agonist as a D-amino peptide calcimimetic for the treatment of secondary hyperparathyroidism. It can bind to and activate the CaSR (calcium-sensing receptor) in the parathyroid gland as an allosteric activator, resulting in PTH reduction and suppression. Amgen Inc. announced its submission of a New Drug Application to the FDA for etelcalcetide in Aug 2015. Group: Pharmaceutical. CAS No. 1334237-71-6. Pack Sizes: 10 mg. Product ID: B0084-475311. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Ethyl (4-((2-(Methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Group: Pharmaceutical. CAS No. 2206827-12-3. Pack Sizes: 100 mg. Product ID: B2694-479756. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
FITC-abaloparatide A Fluorescein isothiocyanate-attached Abaloparatide. Abaloparatide is a parathyroid hormone-related protein (PTHrP) analog drug used to treat osteoporosis. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BAT-006259. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Glutaurine Glutaurine is an endogenous hormone found in the parathyroid and mammalian brain. This compound mimicks the anxiolytic drug diazepam, and has been identified as an antiepileptic. Group: Pharmaceutical. CAS No. 56488-60-9. Pack Sizes: 10 mg. Product ID: BAT-014264. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Lenvatinib Impurities Lenvatinib Impurities, integral to the pharmaceutical sector, play a crucial role in ascertaining Lenvatinib's quality and potency through meticulous identification and quantification of trace constituents. As a tyrosine kinase inhibitor, Lenvatinib targets thyroid, renal, and hepatocellular carcinomas, with impurity surveillance bolstering drug safety and adherence to regulatory mandates. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Levothyroxine EP Impurity F An impurity of Thyroxine which is one of the two major hormones secreted by the thyroid gland and used to stimulate the consumption of oxygen and thus the metabolism of all cells and tissues in the body. Group: Pharmaceutical. CAS No. 911661-90-0. Pack Sizes: 5 mg. Product ID: B2694-413570. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Levothyroxine EP Impurity H An impurity of Levothyroxine. Levothyroxine is used to treat hypothyroidism. Group: Pharmaceutical. CAS No. 2055-97-2. Pack Sizes: 25 mg. Product ID: B0136-412177. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Levothyroxine EP Impurity J An impurity of Levothyroxine. Levothyroxine is used to treat hypothyroidism. Group: Pharmaceutical. CAS No. 4604-41-5. Pack Sizes: 25 mg. Product ID: B2694-390353. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Levothyroxine Impurities Levothyroxine Impurities are crucial reference standards in the biomedical field, particularly in the quality control and formulation development of levothyroxine sodium tablets. These impurities help ensure drug efficacy and safety, addressing thyroid disorders like hypothyroidism by maintaining proper synthesis and dosage precision during drug manufacturing processes. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Levothyroxine sodium Levothyroxine sodium is the hormone derived from thyroid gland. Group: Pharmaceutical. CAS No. 50809-32-0. Pack Sizes: 1 g. Product ID: B0084-069975. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Levothyroxine sodium hydrate 3,3',5,5'-Tetraiodo-L-thyronine sodium saltm is the sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors, the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration, thermogenesis, cellular growth and differentiation, and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects. Group: Pharmaceutical. CAS No. 25416-65-3. Pack Sizes: 100 g. Product ID: BAT-007813. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Liothyronine Sodium Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis. Group: Pharmaceutical. CAS No. 55-06-1. Pack Sizes: 1 g. Product ID: BAT-008129. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Maxacalcitol Impurities Maxacalcitol Impurities occupy a crucial role in the quality assurance protocols of Maxacalcitol synthesis, a synthetic vitamin D derivative utilized for managing psoriasis and secondary hyperparathyroidism. Insight into these impurities is vital for augmenting the compound's potency and safety, thereby guaranteeing superior therapeutic results for affected patients. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Maxacalcitol Intermediate An intermediate of maxacalcitol, which is a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B1128-112381. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Methimazole impurities Methimazole impurities are by-products found in preparations of methimazole, a crucial drug for managing hyperthyroidism. Understanding these impurities aids in ensuring drug safety and efficacy. Additionally, studying these impurities can contribute to refining synthesis processes and improving therapeutic outcomes for thyroid-related disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
MGL-3196 MGL-3196 is a first-in-class, orally available, once-daily and liver-directed thyroid hormone receptor (THR) beta-selective agonist. Studies suggest that MGL-3196 has an attractive, differentiated profile as a potential treatment for non-alcoholic steatohepatitis (NASH) and dyslipidemias. Uses: Potential treatment for non-alcoholic steatohepatitis (nash) and dyslipidemias. Group: Pharmaceutical. CAS No. 920509-32-6. Pack Sizes: 250 mg. Product ID: B0084-008623. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
N-Acetyl-3-iodo-L-tyrosine hemihydrate N-Acetyl-3-iodo-L-tyrosine hemihydrate, a chemical reagent with notable significance in studying enzyme inhibitors and protein synthesis, is widely utilized in the medical research community to develop promising drug therapies for thyroid disorders and cancers. Such compounds may also be used to synthesize radioiodinated compounds, essential in the realm of medical imaging and diagnostics. Uses: Thyronine analog. Group: Pharmaceutical. CAS No. 23277-49-8. Pack Sizes: 100 mg. Product ID: B2699-115435. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
N-Desmethyl Vandetanib N-Desmethyl Vandetanib is a metabolite of Vandetanib. Vandetanib is an antitumor drug used for the treatment of medullary thyroid cancer. Vandetanib effects through inhibiting vascular endothelial growth factor receptor-2 (VEGFR), epidermal growth factor receptor (EGFR) and the RET-tyrosine kinase activity. Group: Pharmaceutical. CAS No. 338992-12-4. Pack Sizes: 5 mg. Product ID: B1926-260255. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Oleuropein Oleuropein is isolated from the herb of Olea europaea L. It inhibits cell proliferation and induces apoptosis in breast cancer, colorectal cancer and thyroid cancer. Oleuropein also has other functions such as anti-ischemic, antioxidative, anti-inflammatory. It can be used in cosmetics material. Uses: Antioxidant activity; anti-inflammatory agent. Group: Pharmaceutical. CAS No. 32619-42-4. Pack Sizes: 500 mg. Product ID: NP3908. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Paricalcitol Synthetic analog of vitamin D. Antihyperparathyroid. Group: Pharmaceutical. CAS No. 131918-61-1. Pack Sizes: 25 mg. Product ID: B0084-057214. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Paricalcitol Impurities Paricalcitol Impurities hold significant importance within the pharmaceutical sector, utilized meticulously to evaluate the purity and stability of paricalcitol formulations. As paricalcitol addresses secondary hyperparathyroidism in chronic kidney disease patients, impurity monitoring is crucial for ensuring therapeutic effectiveness and safety, hence facilitating drug development and regulatory adherence. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Paricalcitol Impurity 1 An impurity of Paricalcitol which is a man-made form of vitamin D to treat and prevent high levels of a certain natural substance made by the body (parathyroid hormone) in patients with long-term kidney disease. Group: Pharmaceutical. CAS No. 1884139-61-0. Pack Sizes: 5 mg. Product ID: B0075-478591. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Paricalcitol Impurity 4 Paricalcitol Impurity 4 is an impurity of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 95716-68-0. Pack Sizes: 25 mg. Product ID: B0075-460980. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Paricalcitol Intermediate A Paricalcitol Intermediate A is an intermediate of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 139356-39-1. Pack Sizes: 250 mg. Product ID: B0075-457976. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Paricalcitol Intermediate CD Paricalcitol Intermediate CD is an intermediate of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 95716-69-1. Pack Sizes: 100 mg. Product ID: B0075-112382. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
PF-1355 PF-1355 is a selective, mechanism-based inhibitor of myeloperoxidase (MPO) (IC50 = 1.5 μM in LPS-stimulated human whole blood) with excellent selectivity for MPO without disrupting a panel of 50 receptors, enzymes, ion channels and transporters, including thyroid peroxidase. PF-1355 was used to test the hypothesis that MPO activity is a critical mediator of disease activity in immune complex vasculitis mouse models, and to support the confidence in rationale for this mechanism as a therapeutic approach to treat related human condition such as alleviating tissue injury caused by Goodpasture syndrome and pulmonary vasculitis induced by immune complexes. Group: Pharmaceutical. CAS No. 1435467-38-1. Pack Sizes: 50 mg. Product ID: B0084-474818. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Potassium Iodide Classed as a metal halide, potassium iodide is a chemical compound that's made from metal (potassium) and halogen (iodine). It has the chemical formula KI and can either appear as a liquid solution, crystals or a white powder. Potassium iodide is commonly used in the medical sector to protect the thyroid during nuclear medicine scintigraphy. It's also used as a dietary supplement to help prevent iodine deficiency. The substance has a neutral or slightly alkaline pH. Uses: Radiation protection. Group: Laboratory Chemicals. Alternative Names: KI. CAS No. 7681-11-0. Pack Sizes: 500G, 1KGs. Chemicals.co.uk
Propylthiouracil Impurities Propylthiouracil Impurities hold paramount importance in maintaining the integrity and stability of the antithyroid agent, propylthiouracil, utilized in addressing hyperthyroidism and Graves' disease. Rigorous monitoring of these impurities enhances pharmaceutical formulations, ensuring both therapeutic efficacy and patient safety in managing thyroid-associated pathologies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
(R)-1- (Naphthalen-1-yl)-N- (3- (trifluoromethyl)benzyl)ethanamine hydrochloride (R)-1- (Naphthalen-1-yl)-N- (3- (trifluoromethyl)benzyl)ethanamine hydrochloride, is an impurity of Cinacalcet, which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels). Group: Pharmaceutical. CAS No. 1229225-42-6. Pack Sizes: 10 mg. Product ID: B2694-379696. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Selpercatinib Selpercatinib is a selective RET inhibitor with antineoplastic activity. It inhibits proliferation of cancer cells containing RET mutations or gene fusions. It is indicated for the treatment of non-small cell lung cancer (NSCLC), medullary thyroid cancer (MTC) and other thyroid cancer tumors. Group: Pharmaceutical. CAS No. 2152628-33-4. Pack Sizes: 1 g. Product ID: B2692-009515. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Sorafenib Impurities Sorafenib Impurities, integral to biomedical exploration, critically evaluate Sorafenib's integrity and safety profile. Essential across hepatic, renal, and thyroid oncological treatments, these impurities augment drug quality by facilitating byproduct identification and control during development, thereby assuring robust and dependable therapeutic efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Sorafenib related compound 10 An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Group: Pharmaceutical. CAS No. 1012058-78-4. Pack Sizes: 10 mg. Product ID: B1630-479761. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Sorafenib Related Compound 15 An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Group: Pharmaceutical. CAS No. 284670-98-0. Pack Sizes: 250 mg. Product ID: B2694-479766. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Sorafenib related compound 2 An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Group: Pharmaceutical. CAS No. 18585-06-3. Pack Sizes: 2 g. Product ID: B2694-233982. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
T4-acetamide An impurity of Levothyroxine. Levothyroxine is used to treat hypothyroidism. Group: Pharmaceutical. CAS No. 176258-88-1. Pack Sizes: 100 mg. Product ID: B0136-473784. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Teriparatide acetate hydrate Teriparatide is a polypeptide and recombinant DNA form of parathyroid hormone consisting of 34 amino acids. It was approved by FDA for the treatment of certain types of osteoporosis. It also has a therapeutic activity for fragility fractures. Uses: The treatment of osteoporosis. Group: Pharmaceutical. CAS No. 99294-94-7. Pack Sizes: 50 mg. Product ID: BAT-009051. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Trametinib A MEK inhibitor that suppresses MEK1 and MEK2 with IC50 of 0.92 and 1.8 nM and no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. It has been approved by FDA, in combination with Tafilnar, for the treatment of metastatic anaplastic thyroid cancer (ATC) with BRAF V600E mutation. Group: Pharmaceutical. CAS No. 871700-17-3. Pack Sizes: 500 mg. Product ID: B0084-307744. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
trans-doxercalciferol Trans-doxercalciferol is an isomer of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Group: Pharmaceutical. CAS No. 74007-20-8. Pack Sizes: 5 mg. Product ID: B1959-261135. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
trans-maxacalcitol Trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 929721-98-2. Pack Sizes: 1 mg. Product ID: B1128-054098. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Tyrosine Impurities Tyrosine Impurities, often evaluated in the biomedical industry, are crucial for ensuring the purity and safety of pharmaceutical formulations containing tyrosine. These impurities are meticulously studied to prevent adverse effects, ensuring efficacy in the treatment of conditions like phenylketonuria and thyroid disorders. Detecting these impurities contributes to developing safer tyrosine-based therapies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
Vandetanib Impurities Vandetanib Impurities, essential components within the pharmaceutical realm, are scrutinized for their role in the purity and safety of vandetanib, a medullary thyroid cancer drug. Through meticulous analysis, these impurities enhance drug efficacy, minimizing potential adverse effects, and optimizing therapeutic impact in cancer management strategies. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London
VER-155008 VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70; IC50 = 0.5 μM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 μM) and glucose-regulated protein 78 (Grp78; KD = 80 nM). VER-155008 inhibits the proliferation of human breast and colon cancer cell lines, inducing apoptosis or caspase-independent cell death. It induces the proteasome-dependent degradation of Hsp90 client proteins and potentiates the apoptotic activity of Hsp90 inhibitors. VER-15508 also triggers paraptosis in anaplastic thyroid carcinoma cells. Group: Pharmaceutical. CAS No. 1134156-31-2. Pack Sizes: 100 mg. Product ID: B1370-272446. Molecular formula: Custom synthesis is available. Send your inquiries for more information. BOC Sciences
London

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