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Thymine-[methyl-d3,6-d1], a ubiquitous component in nucleic acids research, merits consideration in assessments of thymine metabolism. Its incorporation expedites the study of metabolic activities and kinetics of DNA synthesis in cancerous tissues, which necessitate considerably augmented synthesis rates. Group: Pharmaceutical. Alternative Names: thymine-d4 (methyl-d3,6-d1); Thymine-methyl-d3,6-d1; Thymine-methyl-d3,6-d; Thymine-alpha,alpha,alpha,6-d4. CAS No. 156054-85-2. Pack Sizes: 2.5 g. Product ID: BLP-014122. Molecular formula: C5H2D4N2O2. Mole weight: 130.14. Custom synthesis is available. Send your inquiries for more information.
London
7'-Hydroxy-N-tritylmorpholino thymine monomer
7'-Hydroxy-N-tritylmorpholino thymine monomer, a fundamental constituent within the biomedicine realm, assumes paramount importance. Its pivotal function encapsulates nucleic acid analog synthesis, pivotal for scientific inquiry, especially in constructing targeted therapeutic agents against viral infections and select cancer variants. This monomer facilitates the assembly of tailored nucleic acids yielding augmented fortitude, exquisite specificity, and unparalleled efficacy in combating afflictions. Discern its scientific significance and harness its extraordinary potential for transformative outcomes. Group: Pharmaceutical. Alternative Names: 1-((2R,6S)-6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2,4-(1H,3H)-dione; 7'-OH-N-trityl morpholino thymine; 7-hydroxy-N-trityl morpholinothymidine; 2-hydroxymethyl-4-trityl-6-(thymin-1-yl)morpholine. CAS No. 914361-76-5. Pack Sizes: 100 mg. Product ID: B1370-340310. Molecular formula: C29H29N3O4. Mole weight: 483.56. Custom synthesis is available. Send your inquiries for more information.
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O,O´-Bis(trimethylsilyl)thymine
O,O´-Bis(trimethylsilyl)thymine Uses: Pharmaceutical R&D. Group: Intermediates. CAS No. 7288-28-0. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals Suppliers.
UK / EU / USA / Japan
3'-Deoxy-3'-fluorocytidine
3'-Deoxy-3'-fluorocytidine is a purine nucleoside analogue. It is an antiviral agent. Group: Pharmaceutical. Alternative Names: Cytidine, 3-deoxy-3-fluoro-; 3'-Fluoro-3'-deoxycytidine; 1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)thymine; 4-amino-1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-3,4-dihydropyrimidin-2(1H)-one; 3'-F-3'-Dc. CAS No. 123402-20-0. Pack Sizes: 5 mg. Product ID: B1370-279821. Molecular formula: C9H12FN3O4. Mole weight: 245.21. Custom synthesis is available. Send your inquiries for more information.
3'-O-DMT-5-Methy-Uridine-TNA 2'-CE phosphoramidite stands as a fundamental ingredient for the in vitro selection of aptamers; RNA molecules designed for the specific capturing of target molecules, including drugs and disease biomarkers. Synthesized using this crucial element, these aptamers have enormous potential for application in both drug discovery and diagnostics research fields. Group: Pharmaceutical. Alternative Names: DMTr-TNA-5MeU-amidite; 1-[(2R)-3alpha-[(Diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]thymine; T-TNA Phosphoramidite. CAS No. 325683-94-1. Pack Sizes: 1 g. Product ID: B1370-376750. Molecular formula: C39H47N4O8P. Mole weight: 730.8. Custom synthesis is available. Send your inquiries for more information.
London
DAPI dihydrochloride
DAPI is a fluorescent DNA stain that binds to the minor groove of double-stranded DNA with preference for adenine and thymine (AT) rich DNA. DAPI is commonly used in microscopy and flow cytometry. It can be used on either fixed or live cells, although it crosses membranes in live cells less efficiently and demands higher concentrations to be used. Uses: Suitable for dna staining in agarose gels, analysis of changes in dna during apoptosis, detection of mycoplasma, photofootprinting of dna, immunofluorescent staining of cells. Group: Pharmaceutical. Alternative Names: DAPI;2-[4-(aminoiminomethyl)phenyl]-1H-indole-6-carboximidamide dihydrochloride. CAS No. 28718-90-3. Pack Sizes: 250 mg. Product ID: B2708-089411. Molecular formula: C16H15N5·2HCl. Mole weight: 350.3. Custom synthesis is available. Send your inquiries for more information.
London
(S)-homo-β-alanine
(S)-Homo-β-alanine, an amino acid occurring naturally, acts as an intermediary in thymine metabolism. Its potential to regulate oxidative stress and inflammation marks it as a prospective treatment for cardiovascular disease and hypertension. Also, research suggests its involvement in the synthesis of neurotransmitter gamma-aminobutyric acid (GABA) in the brain. Group: Pharmaceutical. Alternative Names: (S)-beta-homoalanine. CAS No. 3775-72-2. Pack Sizes: 10 g. Product ID: B2699-114069. Molecular formula: C4H9NO2. Mole weight: 103.11. Custom synthesis is available. Send your inquiries for more information.
London
Zidovudine
Zidovudine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM). It is commonly used in combination therapy to slow the replication of HIV in vivo. Uses: Anti-hiv agents; antimetabolites; antimetabolites, antineoplastic; reverse transcriptase inhibitors. Group: Pharmaceutical. Alternative Names: 3'-Azido-3-deoxythymidine; AZT; BWA509U; BWA 509U; BWA-509U; ZDV; Azidothymidine; Retrovir; Timazid; NSC 602670; 3'-Azido-2',3'-dideoxythymidine; 1-(3-Azido-2,3-dideoxy-β-D-glycero-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,4S,5S)-4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidin-2,4(1H,3H)-dione; 1-(3-Azido-2,3-dideoxy-β-D-ribofuranosyl)thymine. CAS No. 30516-87-1. Pack Sizes: 100 g. Product ID: NP3476. Molecular formula: C10H13N5O4. Mole weight: 267.24. Custom synthesis is available. Send your inquiries for more information.
London
2-Deoxy-D-Ribose
2-Deoxy-D-Ribose. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 533-67-5. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: thyminose.
5'-O-DMT-2'-O-TBDMS-5-Methyl-Uridine 3'-CE phosphoramidite is a modified phosphoramidite reagent used in oligonucleotide synthesis. This compound features protective groups: a dimethoxytrityl (DMT) group at the 5'-hydroxyl position, a tert-butyldimethylsilyl (TBDMS) group at the 2'-hydroxyl position, and a cyanoethyl (CE) protecting group on the phosphoramidite moiety. These modifications allow for the efficient incorporation of 5-methyluridine into synthetic oligonucleotides, enhancing their stability and binding affinity, which is crucial for applications in genetic research and therapeutic development. Group: Pharmaceutical. Alternative Names: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5-Methyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-uridine-3'-cyanoethyl phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-2-O-(tert-butyl-dimethyl-silyl)-1-deoxy-1-thymin-1-yl-beta-D-ribo. CAS No. 159639-78-8. Pack Sizes: 500 mg. Product ID: B1370-291978. Molecular formula: C46H63N4O9PSi. Mole weight: 875.09. Custom synthesis is available. Send your inquiries for more information.
London
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