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2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl-(N2-Fmoc)-L-threonine is a biomedical compound commonly utilized in the development and synthesis of peptide-based drugs. It plays a crucial role as a protecting group for the amino acid threonine during peptide synthesis. With its precise chemical properties, it ensures the accurate and controlled assembly of peptide sequences, making it an tool in drug development and disease research. Group: Pharmaceutical. CAS No. 127656-85-3. Pack Sizes: 100 mg. Product ID: BAT-008970. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl-Fmoc threonine is a glycosylated amino acid used in the synthesis of Fmoc solid-phase peptide. Group: Pharmaceutical. CAS No. 160168-40-1. Pack Sizes: 100 mg. Product ID: BAT-015387. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetyl-L-threonine
Acetyl-L-threonine. Group: Pharmaceutical. CAS No. 17093-74-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-003877. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Acetyl-L-threonine methyl ester
Acetyl-L-threonine methyl ester. Group: Pharmaceutical. CAS No. 2458-78-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-003878. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Acetyl-O-tert-butyl-L-threonine
Acetyl-O-tert-butyl-L-threonine. Group: Pharmaceutical. CAS No. 163277-80-3. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-003885. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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DL-Threonine
100g Pack Size. Group: Amino Acids, Biochemicals. Formula: C4H9NO3. CAS No. 80-68-2. Prepack ID : 19522182-100g. Molecular Weight : 119.12.
DL-Threonine
25g Pack Size. Group: Amino Acids, Biochemicals. Formula: C4H9NO3. CAS No. 80-68-2. Prepack ID : 19522182-25g. Molecular Weight : 119.12.
Fmoc-L-Threonine
25g Pack Size. Group: Amino Acids. Formula: C19H19NO5. CAS No. 73731-37-0. Prepack ID : 61802005-25g. Molecular Weight : 341.36.
H-D-allo-Threonine Methyl Ester Hydrochloride
H-D-allo-Threonine Methyl Ester Hydrochloride is used to prepare hepatitis A virus 3C cysteine protease inhibitors. Group: Pharmaceutical. CAS No. 60538-18-3. Pack Sizes: 1 g. Product ID: B2699-039416. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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L-Threonine
100g Pack Size. Group: Amino Acids. Formula: C4H9NO3. CAS No. 72-19-5. Prepack ID : 29578582-100g. Molecular Weight : 119.12.
L-Threonine
500g Pack Size. Group: Amino Acids. Formula: C4H9NO3. CAS No. 72-19-5. Prepack ID : 29578582-500g. Molecular Weight : 119.12.
L-Threonine
L-Threonine Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 72-19-5. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply.
UK / EU / USA / Japan
BX-795
3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. It is also a potent and relatively specific inhibitor of TBK1 with IC50 of 6 nM and IKK? with IC50 of 41 nM. Group: Pharmaceutical. CAS No. 702675-74-9. Pack Sizes: 25 mg. Product ID: B0084-194478. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Cobimetinib
Cobimetinib (GDC-0973, RG7420) is a potent, orally available and highly selective MEK1 inhibitor with IC50 of 4.2 nM. It shows more than 100-fold selectively for MEK1 over MEK2 when tested against a panel of more than 100 serine-threonine and tyrosine kinases and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Group: Pharmaceutical. CAS No. 934660-93-2. Pack Sizes: 25 mg. Product ID: B0084-460683. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Marizomib
Marizomib is a naturally-occurring salinosporamide, isolated from the marine actinomycete Salinospora tropica, with potential antineoplastic activity. Marizomib irreversibly binds to and inhibits the 20S catalytic core subunit of the proteasome by covalently modifying its active site threonine residues. Group: Pharmaceutical. CAS No. 437742-34-2. Pack Sizes: 1 mg. Product ID: BBF-05732. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
PD0325901
PD-0325901 is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. Uses: Reprogramming, self-renewal. Group: Pharmaceutical. CAS No. 391210-10-9. Pack Sizes: 100 mg. Product ID: B0084-091588. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Tozasertib
The Aurora kinases (A, B, and C) are a family of serine-threonine kinases that regulate various stages of mitotic function. With significant roles in cell cycle and cell division, Aurora kinase gene amplification and overexpression are linked to tumorigenesis. MK 0457 is a potent pan-Aurora kinase inhibitor but favors Aurora A (Ki = 0.6 nM) over Aurora B (Ki = 18 nM) or Aurora C (Ki = 4.6 nM). It shows selectivity against a panel of more than 190 different protein kinases. MK 0457 effectively inhibits proliferation of several different cell lines of clear cell renal carcinoma (IC50s < 10 μM) and blocks the growth of tumors in a rodent model of cancer (80 mg/kg), inhibiting histone H3 phosphorylation and increasing apoptosis. By depleting Aurora activity, MK 0457 disrupts bipolar spindle formation during mitosis, arresting cell cycle progression at the G2/M phase. Group: Pharmaceutical. CAS No. 639089-54-6. Pack Sizes: 250 mg. Product ID: B0084-074159. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Tricirbine
Triciribine is a potent AKT inhibitor and a cell-permeable tricyclic nucleoside molecule with potential antineoplastic activity. Akt-1, -2, and -3 are serine/threonine protein kinases in the phosphatidylinositol (PI3)-kinase signalling pathway that play a critical role in the regulation of cell proliferation and survival. Following recruitment of Akt to the plasma membrane, phosphorylation at threonine 308 and serine 473 (Akt-1 numbering) by phosphoinositide-dependent kinases (PDK) 1 and 2 results in full activation of the enzyme. Triciribine is a cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3. It does not inhibit phosphatidylinositol 3 (PI3)-Kinase or PDK1, the direct upstream activators of Akt, nor does it inhibit PKC, PKA, ERK1/2, serum- and glucocorticoid-inducible kinase, p38, STAT3, or JNK signalling pathways. Triciribine effectively inhibits growth of Akt-overexpressing human cancer cell lines in vitro with 50% inhibition at ~5-10 μM. It also inhibit growth of tumor xenografts in mice by greater than 80% at a dose of 1 mg/kg/day. Group: Pharmaceutical. CAS No. 35943-35-2. Pack Sizes: 100 mg. Product ID: B1370-090988. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
L-Threoninol(Ac)-8-Octreotide trifluoroacetate salt
Threoninol(Ac)-8-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-449816. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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