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| Product | Description | |
|---|---|---|
| Thalidomide 4'-ether-alkylC2-amine hydrochloride | Thalidomide 4'-ether-alkylC2-amine hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a short C2 alkyl linker with terminal amine for covalent binding, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Group: Pharmaceutical. Alternative Names: Thalidomide - linker 6. CAS No. 2341840-99-9. Pack Sizes: 500 mg. Product ID: B2693-008870. Molecular formula: C15H16ClN3O5. Mole weight: 353.76. Custom synthesis is available. Send your inquiries for more information. |  London |
| Thalidomide-O-amido-C6-NH2 (TFA) | Thalidomide-O-amido-C6-Amine trifluoroacetate is a PROTAC block consist of Thalidomide linked to alkyl with Amine functional group for conjugation reactions. Group: Pharmaceutical. Alternative Names: Thalidomide-O-amido-C6-NH2 (TFA); Cereblon Ligand-Linker Conjugates 11 (TFA); E3 Ligase Ligand-Linker Conjugates 25 (TFA); Thalidomide-O-amido-C6-Amine Trifluoroacetate; N-(6-aminohexyl)-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid. CAS No. 1950635-14-9. Pack Sizes: 100 mg. Product ID: B2693-008754. Molecular formula: C23H27F3N4O8. Mole weight: 544.48. Custom synthesis is available. Send your inquiries for more information. | London |
| Thalidomide-O-amido-C8-NH2 (TFA) | Thalidomide-O-amido-C8-NH2 (TFA) is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology. Group: Pharmaceutical. Alternative Names: E3 Ligase Ligand-Linker Conjugates 17. CAS No. 1950635-16-1. Pack Sizes: 100 mg. Product ID: B2693-008757. Molecular formula: C25H31F3N4O8. Mole weight: 572.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Thalidomide-O-C4-NH2 hydrochloride | Thalidomide-O-C4-NH2 hydrochloride is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C4 alkyl linker with terminal amine, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Group: Pharmaceutical. Alternative Names: Thalidomide-linker 9. CAS No. 2376990-29-1. Pack Sizes: 100 mg. Product ID: B1370-292464. Molecular formula: C17H20ClN3O5. Mole weight: 381.81. Custom synthesis is available. Send your inquiries for more information. | London |
| Thalidomide-O-C7-acid | Thalidomide-O-C7-acid is a synthetic E3 ligand-linker conjugate containing a cereblon ligand based on Thalidomide and a C7 alkyl linker with a terminal carboxylic acid, as a part of a variety of functionalized PROTAC molecules for binding to a target protein ligand. Group: Pharmaceutical. CAS No. 2169266-70-8. Pack Sizes: 100 mg. Product ID: BP-100132. Molecular formula: C21H24N2O7. Mole weight: 416.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Thalidomide, propargyl | Thalidomide, propargyl is a cereblon-recruiting ligand consisting of an E3 ubiquitin ligase thalidomide conjugated to an alkyne linker ready for a target protein ligand. It has been used in PROTAC technology for target protein degradation. Group: Pharmaceutical. Alternative Names: 2-(2,6-Dioxo-3-piperidinyl)-4-(2-propyn-1-yloxy)-1H-isoindole-1,3(2H)-dione. CAS No. 2098487-39-7. Pack Sizes: 1 g. Product ID: B2693-285284. Molecular formula: C16H12N2O5. Mole weight: 312.28. Custom synthesis is available. Send your inquiries for more information. | London |
| (+/-)-Thalidomide | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C13H10N2O4. CAS No. 50-35-1. Prepack ID : 86297062-1g. Molecular Weight : 258.23. |  |
| dBET1 | dBET1 is a potent BRD4 protein degrader composed of a BET bromodomain inhibitor (+)-JQ1 and a sedative drug thalidomide. The (+)-JQ1 portion binds to the BET bromodomains, and the thalidomide binds to cereblon to form a cereblon E3 ubiquitin ligase complex, inducing cereblon-dependent BET protein degradation. Group: Pharmaceutical. Alternative Names: (6S)-4-(4-chlorophenyl)-N-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide. CAS No. 1799711-21-9. Pack Sizes: 50 mg. Product ID: B1370-285214. Molecular formula: C38H37ClN8O7S. Mole weight: 785.27. Custom synthesis is available. Send your inquiries for more information. | London |
| TC-E3 5032 | TC-E3 5032 is a linker used in PROTAC technology that can be used in the synthesis of HDAC6 and anaplastic lymphoma kinase (ALK) degraders. Group: Pharmaceutical. Alternative Names: E3 ligase Ligand 4; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-; Thalidomide 4-fluoride; Thalidomide fluoride; 4-Fluoro-thalidomide; Cereblon ligand 4;E3 ligase Ligand 4; 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione. CAS No. 835616-60-9. Pack Sizes: 5 g. Product ID: BAT-006490. Molecular formula: C13H9FN2O4. Mole weight: 276.22. Custom synthesis is available. Send your inquiries for more information. | London |
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