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An impurity of Finasteride. Finasteride is a 4-azasteroid analog of testosterone that competitively blocks type II 5α-reductase activity with 100-fold greater affinity than for the type I enzyme. Group: Pharmaceutical. Alternative Names: 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid. CAS No. 104239-97-6. Pack Sizes: 1mg;1g;10g. Product ID: NP3132. Molecular formula: C19H27NO3. Mole weight: 317.42. Custom synthesis is available. Send your inquiries for more information.
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Abarelix
Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Group: Pharmaceutical. Alternative Names: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. CAS No. 183552-38-7. Pack Sizes: 10 mg. Product ID: BAT-006166. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. Custom synthesis is available. Send your inquiries for more information.
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ASP-9521
ASP9521 is a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3). ASP9521 has demonstrated anti-tumour activity in in vitro and in vivo preclinical models. ASP9521 inhibited conversion of androstenedione (AD) into testosterone (T) by recombinant human or cynomolgus monkey AKR1C3 in a concentration-dependent manner. Group: Pharmaceutical. Alternative Names: ASP9521; ASP-9521; ASP 9521. AKR1C3 inhibitor ; 17HSD5 inhibitor;4-(2-Hydroxy-2-methylpropyl)piperidino(5-methoxy-1H-indole-2-yl)methanone; 1-[1-[(5-Methoxy-1H-indol-2-yl)carbonyl]piperidin-4-yl]-2-methylpropan-2-ol. CAS No. 1126084-37-4. Pack Sizes: 100 mg. Product ID: B0084-462669. Molecular formula: C19H26N2O3. Mole weight: 330.428. Custom synthesis is available. Send your inquiries for more information.
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Degarelix
Degarelix acetate is a reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist. Degarelix reduces the secretion of luteinizing hormone (LH) and testosterone via blocking GnRHR. Degarelix can be used for the treatment of prostate cancer. Group: Pharmaceutical. Alternative Names: Degarelix; Firmagon; FE-200486; FE 200486; FE200486; ASP-3550; ASP 3550; ASP3550; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Phe(4-S-dihydroorotamido)-D-Phe(4-ureido)-Leu-Lys(iPr)-Pro-D-Ala-NH2. CAS No. 214766-78-6. Pack Sizes: 10 mg. Product ID: BAT-010776. Molecular formula: C82H103ClN18O16. Mole weight: 1632.286. Custom synthesis is available. Send your inquiries for more information.
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Degarelix acetate hydrate
Degarelix acetate is a synthetic peptide that acts as a gonadotrophin-releasing hormone (GnRH) antagonist. Degarelix targets GnRH receptors in the pituitary gland, resulting in reduction of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and suppression of testosterone. Group: Pharmaceutical. Alternative Names: FE-200486; FE 200486; FE200486; ASP-3550; ASP 3550; ASP3550. CAS No. 934246-14-7. Pack Sizes: 100 mg. Product ID: BAT-010777. Molecular formula: C84H109ClN18O19. Mole weight: 1710.32. Custom synthesis is available. Send your inquiries for more information.
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Dutasteride
Dutasteride is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Group: Pharmaceutical. Alternative Names: 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-[2,5-Bis(trifluoromethyl)phenyl]-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide; 4-Azaandrost-1-ene-17-carboxamide, N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-, (5α,17β)-; (5α,17β)-N-[(2,5-Bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5-androst-1-ene-17-carboxamide; Avodart; Avolve; GG 745; GI 198745; Veltride. CAS No. 164656-23-9. Pack Sizes: 1mg;1g;10g. Product ID: NP3151. Molecular formula: C27H30F6N2O2. Mole weight: 528.53. Custom synthesis is available. Send your inquiries for more information.
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Finasteride
Finasteride (INN, USAN, BAN) (brand names Proscar, and Propecia by Merck, among other generic names; former developmental code name MK-906) is a drug used for the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB). It is a type II and type III 5α-reductase inhibitor; 5α-reductase, an enzyme, converts testosterone to dihydrotestosterone (DHT). Uses: Api. Group: Pharmaceutical. Alternative Names: MK-906; MK 906; MK906; Propecia; Proscar; N-tert-Butyl-3-oxo-4-aza-5α-androst-1-en-17β-carboxamide; N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide. CAS No. 98319-26-7. Pack Sizes: 50 g. Product ID: NP3378. Molecular formula: C23H36N2O2. Mole weight: 372.5. Custom synthesis is available. Send your inquiries for more information.
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Finasteride EP Impurity B
An intermediate in the synthesis of Finasteride. Finasteride is a 4-azasteroid analog of testosterone that competitively blocks type II 5α-reductase activity with 100-fold greater affinity than for the type I enzyme. Group: Pharmaceutical. Alternative Names: Dutasteride Methyl ester Imp; Dutasteride Ester Impurity; 4-Azaandrost-1-ene-17-carboxylic acid, 3-oxo-, methyl ester, (5α,17β)-; 17β-(Methoxycarbonyl)-4-aza-5α-androst-1-en-3-one; 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 1,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, methyl ester, [4aR-(4aα,4bβ,6aα,7α,9aβ,9bα,11aβ)]-; 3-Oxo-4-aza-5α-androst-1-en-17β-carboxylic acid methyl ester; Methyl 3-oxo-4-aza-5α-androst-1-ene-17β-carboxylate; Dutasteride methyl ester; Finasteride Methyl Ester Analog. CAS No. 103335-41-7. Pack Sizes: 100 mg. Product ID: B2694-255935. Molecular formula: C20H29NO3. Mole weight: 331.46. Custom synthesis is available. Send your inquiries for more information.
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FOXO4-DRI
FOXO4-DRI is a peptide acting as a specific FOXO4 blocker. It has been demonstrated to alleviate age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice.FOXO4-DRI is a peptide acting as a specific FOXO4 blocker. It has been demonstrated to alleviate age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. FOXO4-DRI is a standard FOXO4 protein that is synthesized to prevent normal FOXO4 from binding to p53, thereby eliminating senescent cells and improving organ function and the ''biological age'' of young tissues. FOXO4-DRI affects a variety of cellular processes, including insulin signaling, cell cycle regulation, and oxidative stress signaling pathways, it is a cell-penetrative peptide, meaning it can enter cells from the inside and perform its role, and it has been shown in animal studies to selectively induce apoptosis in senescence cells, potentially reversing some of the effects of aging. Group: Pharmaceutical. Alternative Names: FOXO 4-DRI; Anti-aging peptide FOXO4-DRI; H-D-Leu-D-Thr-D-Leu-D-Arg-D-Lys-D-Glu-D-Pro-D-Ala-D-Ser-D-Glu-D-Ile-D-Ala-D-Gln-D-Ser-D-Ile-D-Leu-D-Glu-D-Ala-D-Tyr-D-Ser-D-Gln-D-Asn-D-Gly-D-Trp-D-Ala-D-Asn-D-Arg-D-Arg-D-Ser-D-Gly-D-Gly-D-Lys-D-Arg-D-Pro-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Lys-D-Lys-D-Arg-D-Gly-OH; Forkhead box O transcription factor 4-D-Retro-Inverso; Proxofim; D-Retro Inv. CAS No. 2460055
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Nilutamide
Nilutamide is a non-steroidal and silent antiandrogen that binds to androgen receptors and also inhibits androgen biosynthesis in vitro. In rats in vivo it inhibits androgen-induced prostate weight increase and inhibits negative androgen-dependent gonadotropin feedback leading to an increase in luteinising hormone and testosterone. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: Anandron; Nilandron; 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione. CAS No. 63612-50-0. Pack Sizes: 10 g. Product ID: B2693-465325. Molecular formula: C12H10F3N3O4. Mole weight: 317.224. Custom synthesis is available. Send your inquiries for more information.
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ODM-201
ODM-201 is a new-generation, potent and selective androgen receptor (AR) inhibitor which is potential useful for treatment of castration-resistant prostate cancer (CRPC). ODM-201 is a full and high-affinity AR antagonist that, similar to second-generation antiandrogens enzalutamide and ARN-509, inhibits testosterone-induced nuclear translocation of AR. Group: Pharmaceutical. Alternative Names: ODM-201; ODM 201; ODM201. CAS No. 1297538-32-9. Pack Sizes: 100 mg. Product ID: B0084-470833. Molecular formula: C19H19ClN6O2. Mole weight: 389.85. Custom synthesis is available. Send your inquiries for more information.
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Paeoniflorin
Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has antiandrogenic properties. Paeoniflorin inhibits the production of testosterone and promotes the activity of aromatase-the enzyme that converts testosterone into estrogen. Uses: Antiandrogenic properties. Group: Pharmaceutical. Alternative Names: 9[(Benzoyioxy)methyl]-1-(b-D-glucopyranosyloxy)-4,8-epoxy-6-methyl-7-oxaticyclo[4,3,0,0]nonane. CAS No. 23180-57-6. Pack Sizes: 500 mg. Product ID: NP4515. Molecular formula: C23H28O11. Mole weight: 480.46. Custom synthesis is available. Send your inquiries for more information.
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Secalciferol
Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification. lt mediates calcium and phosphorus homeostasis and inhibits calcium channels in osteosarcoma cells via suppressing the effects of 1α, 25-dihydroxyvitamin D3 and testosterone. lt also can decrease the abundance of p53 and Pi-induced cytochrome c translocation. Uses: Bone density conservation agents. Group: Pharmaceutical. Alternative Names: (24R)-24,25-Dihydroxyvitamin D3; Osteo D; (24R)-Hydroxycalcidiol. CAS No. 55721-11-4. Pack Sizes: 1 mg. Product ID: B0084-375020. Molecular formula: C27H44O3. Mole weight: 416.64. Custom synthesis is available. Send your inquiries for more information.
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