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| Product | Description | |
|---|---|---|
| Tenofovir Alafenamide | Tenofovir Alafenamide is a prodrug of Tenofovir, which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral. Group: Pharmaceutical. Alternative Names: (S)-isopropyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate; GS7340; GS-7340; GS 7340; Tenofovir alafenamide. CAS No. 379270-37-8. Pack Sizes: 200 mg. Product ID: B0084-463638. Molecular formula: C21H29N6O5P. Mole weight: 476.47. Custom synthesis is available. Send your inquiries for more information. |  London |
| Tenofovir Alafenamide-[d5] (diastereomers) | An isotope labelled derivative of Tenofovir alafenamide. Tenofovir alafenamide is a nucleotide reverse transcriptase inhibitor and a prodrug of tenofovir. Tenofovir is an antiretroviral used for HIV treatment. Group: Pharmaceutical. Alternative Names: Tenofovir Alafenamide-d5 (diastereomers); GS 7171-d5; 1-Methylethyl Ester N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl] phenoxyphosphinyl]-L-alanine-d5. CAS No. 2131003-68-2. Pack Sizes: 10 mg. Product ID: BLP-006020. Molecular formula: C21H24D5N6O5P. Mole weight: 481.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Tenofovir alafenamide hemifumarate | Tenofovir alafenamide hemifumarate, also known as Tenofovir alafenamide fumarate (2:1), is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevents HIV from multiplying and can reduce the amount of HIV in the body. Group: Pharmaceutical. Alternative Names: Isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate hemifumarate; TAF; GS734; GS-734; GS 734; GS 7340; GS-7340; GS7340; Tenofovir alafenamide fumarate (2:1). CAS No. 1392275-56-7. Pack Sizes: 200 mg. Product ID: B0084-470850. Molecular formula: C46H62N12O14P2. Mole weight: 1069.02. Custom synthesis is available. Send your inquiries for more information. | London |
| Tenofovir Alafenamide PMPA Impurity | One impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Group: Pharmaceutical. Alternative Names: Tenofovir Dimer; Bis((((R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)diphosphonic Acid. CAS No. 1607007-18-0. Pack Sizes: 10 mg. Product ID: B2694-172640. Molecular formula: C18H26N10O7P2. Mole weight: 556.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Bictegravir | Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM for strand transfer activity. Bictegravir is a drug of the integrase inhibitor class that was copied from Dolutegravir by scientists at Gilead Sciences. Bictegravir also inhibits HIV-1 viral infection in MT-2 and MT-4 cells, CD4+ T cells, and macrophages (EC50s = 1.5, 2.5, 1.5, and 6.6 nM, respectively) without exhibiting cytotoxicity (CC50s = 10.3, 3.7, 13, and 29.8 μM, respectively). In 2016, bictegravir was in a Phase 3 trial as part of a single tablet regimen in combination with tenofovir alafenamide (TAF) and emtricitabine (FTC) for the treatment of HIV-1 infection. Group: Pharmaceutical. Alternative Names: GS-9883; GS 9883; GS9883. CAS No. 1611493-60-7. Pack Sizes: 100 mg. Product ID: B2693-058383. Molecular formula: C21H18F3N3O5. Mole weight: 449.39. Custom synthesis is available. Send your inquiries for more information. | London |
| Cobicistat | Cobicistat is a potent inhibitor of cytochrome P450 3A enzymes, including the important CYP3A4 subtype. It also inhibits intestinal transport proteins, increasing the overall absorption of several HIV medications, including atazanavir, darunavir and tenofovir alafenamide fumarate. Uses: Anti-hiv agents. Group: Pharmaceutical. Alternative Names: Cobicistat, GS-9350; GS 9350; GS9350. CAS No. 1004316-88-4. Pack Sizes: 25 mg. Product ID: B0084-456314. Molecular formula: C40H53N7O5S2. Mole weight: 776.028. Custom synthesis is available. Send your inquiries for more information. | London |
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