Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
25g Pack Size. Group: Biochemicals, Building Blocks, Diagnostic Raw Materials, Peptide Reagents. Formula: C11H15BClF4N5O. CAS No. 330641-16-2. Prepack ID : 20715486-25g. Molecular Weight : 355.53.
TC-S 7001
TC-S 7001 is a potent and highly selective ROCK inhibitor. Its IC50 values are 0.6 and 1.1 nM for ROCK1 and ROCK2, respectively. It exhibits >200-fold selectivity over TRK and FLT3 receptors, and >900-fold selectivity over a panel of other kinases and cardiovascular relevent enzymes and receptors. It reduces blood pressure in normotensive and hypertensive rats. Group: Pharmaceutical. Alternative Names: TC-S 7001; TC S 7001; TCS 7001; TC-S-7001; TCS7001; Azaindole-1; Azaindole 1; 6-Chloro-N4-{3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl}pyrimidine-2,4-diamine;Rho Kinase Inhibitor;ROCK inhibitor;ROCK. CAS No. 867017-68-3. Pack Sizes: 5 mg. Product ID: B2693-430574. Molecular formula: C18H13ClF2N6O. Mole weight: 402.79. Custom synthesis is available. Send your inquiries for more information.
London
Tris (1- chloro- 2- propyl) phosphate (TCPP)
Tris (1- chloro- 2- propyl) phosphate (TCPP), CAS 1244733-77-4, Flame Retardants, Coatings. Formerly Lansdowne Chemicals
5,10,15,20-(tetra-4-carboxyphenyl)porphyrin is a sensor for Ni2+. Group: Pharmaceutical. Alternative Names: Meso-Tetra(4-carboxyphenyl)porphine; Meso-tetraphenylporphine-4,4',4'',4'''-tetracarboxylic acid; Tetrakis (4-carboxyphenyl) porphyrin; TCPP; Nickel ionophore II. CAS No. 14609-54-2. Pack Sizes: 25 g. Product ID: B1370-186003. Molecular formula: C48H30N4O8. Mole weight: 790.77. Custom synthesis is available. Send your inquiries for more information.
London
Abanoquil mesilate
This molecular is an active biochemical as a Alpha 1 adrenergic receptor antagonist. However, no developments were reported for Ischaemic heart disorders and Arrhythmias. Uses: Arrhythmias; ischaemic heart disorders. Group: Pharmaceutical. Alternative Names: 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine;methanesulfonic acid,TCMDC-131968, TCMDC 131968, TCMDC131968, UK 52046; UK-52046; UK52046; Abanoquil. CAS No. 118931-00-3. Pack Sizes: 1mg;1g;10g. Product ID: 118931-00-3. Molecular formula: C23H29N3O7S. Mole weight: 491.56. Custom synthesis is available. Send your inquiries for more information.
London
BML-284
BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro. Uses: Bml-284 may be a useful tool in the study of physiological processes that involve the wnt pathway. Group: Pharmaceutical. Alternative Names: BML 284; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine. CAS No. 853220-52-7. Pack Sizes: 25 mg. Product ID: B0084-474867. Molecular formula: C19H18N4O3. Mole weight: 350.37. Custom synthesis is available. Send your inquiries for more information.
London
Calcium phosphate (3:2)
Calcium Phosphate can be used as an anti-caking agent, acidity regulator, nutritional supplement, flavoring agent, stabilizer and moisture retention agent. Calcium phosphate was used as an adjuvant in France in diphtheria, tetanus, pertussis, and poliomyelitis vaccines. Group: Pharmaceutical. Alternative Names: Phosphoric acid, calcium salt (2:3); Allogran-R; Bonarka; Calciresorb; Calcium orthophosphate (Ca3(PO4)2); Calcium phosphate; Calcium phosphate (Ca1.5(PO4)); Calcium phosphate (Ca10.5(PO4)7); Calcium tertiary phosphate; Cerasorb; Cerasorb Curasan; DET 10; EPSolute Instant S; JAX TCP; Mastergraft; Osferion; Phosphoric acid calcium(2+) salt (2:3); Posture; Synthograft; Tertiary calcium phosphate; Versacal MP; Vitoss; α-Tricalcium phosphate; β-TCP; β-Tricalcium phosphate; β-Whitlockite; Tricalcium phosphate. CAS No. 7758-87-4. Pack Sizes: 10 g. Product ID: B0001-308437. Molecular formula: Ca3O8P2. Mole weight: 310.18. Custom synthesis is available. Send your inquiries for more information.
London
Candesartan cilexetil
Candesartan blocks the effects of angiotensin II at the angiotensin II type 1 (AT1) receptor. Candesartan cilexetil is a prodrug that is activated to candesartan by ester hydrolysis during gastrointestinal absorption. Uses: Antihypertensive agents. Group: Pharmaceutical. Alternative Names: TCV-116; TCV 116; TCV116; Candesartan cilexetil. CAS No. 145040-37-5. Pack Sizes: 50 g. Product ID: NP3201. Molecular formula: C33H34N6O6. Mole weight: 610.66. Custom synthesis is available. Send your inquiries for more information.
London
Exenatide acetate
Exenatide acetate is a potent peptide agonist of the glucagon-like peptide 1 (GLP-1) receptor with Ki value of 136 pM. It is a 39 amino acid peptide, which increases intracellular cAMP in pancreatic acinar cells and has no effect on VIP receptors. It was first isolated from the venom of H. horridum and consequently synthesized. It stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1 receptor-dependent mechanism. It also stimulates glucose-induced insulin secretion in isolated rat islets and proinsulin expression in mouse insulinoma βTC-1 cells. It protects hippocampal neurons against glutamate-induced apoptosis, suggesting utility in neurodegenerative diseases. It also has anxiolytic and anti-depressant effects and induces satiety. It is an incretin mimetic approved for type 2 diabetes mellitus treatment. It also has neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. Group: Pharmaceutical. Alternative Names: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L
London
iCRT 14
iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling. It is thought to directly influence the interaction between β-catenin and TCF4. It also induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines. Group: Pharmaceutical. Alternative Names: iCRT14; iCRT-14; iCRT 14; Wnt inhibitor; CHEMBL3589010; STK155594; 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione. CAS No. 677331-12-3. Pack Sizes: 25 mg. Product ID: B0084-272145. Molecular formula: C21H17N3O2S. Mole weight: 375.44. Custom synthesis is available. Send your inquiries for more information.
London
lofepramine hydrochloride
Lofepramine is a tricyclic antidepressant (TCA) indicated for the treatment of depression. It functions via inhibiting 5-HT and NA reuptake. Group: Pharmaceutical. Alternative Names: N-(4-CHLOROBENZOYLMETHYL)-3-(10,11-DIHYDRO-5H-DIBENZ[B,F]AZEPIN-5-YL)-N-METHYLPROPYLAMINE HYDROCHLORIDE; LOFEPRAMINE HCL; LOFEPRAMINE HYDROCHLORIDE; 4'-chloro-2-((3-(10,11-dihydro-5h-dibenz(b,f)azepin-5-yl)propyl)methylamino); acetophenone,4'-chloro-2-((3-(1. CAS No. 26786-32-3. Pack Sizes: 50 g. Product ID: B2693-064646. Molecular formula: C26H28Cl2N2O. Mole weight: 455.426. Custom synthesis is available. Send your inquiries for more information.
London
(±)-Naringenin
Naringenin is an estrogen receptor binding inhibitor produced by Streptomyces graminofaciens BA 14348. Uses: Anti-ulcer agents. Group: Pharmaceutical. Alternative Names: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-; 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (R,S)-Naringenin; (RS)-Naringenin; (±)-5,7,4'-Trihydroxyflavanone; 4',5,7-Trihydroxyflavanone; 5,7,4'-Trihydroxyflavanone; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chroman-4-one; 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one; ST 057236; TCI-CA 03. CAS No. 67604-48-2. Pack Sizes: 100 g. Product ID: BBF-03516. Molecular formula: C15H12O5. Mole weight: 272.25. Custom synthesis is available. Send your inquiries for more information.
O-(6-Chloro-1-hydrocibenzotriazol-1-yl)- -1,1,3,3-Tetra methyl uronium tetra fluoroborate Uses: Pharmaceutical R&D. Group: Coupling Reagents. Alternative Names: TCTU. CAS No. 330641-16-2. Pack Sizes: Enquire for MOQ. Categories: NORDMANN Key intermediates and specialty chemicals suppliers.
UK / EU / USA / Japan
Saikosaponin H
Saikosaponin H is a saikosaponins standard extracted from the Bupleuri Radix (Bupleurum spp. root) which is one of the most important crude drugs used inmany traditional Chinesemedicines (TCM). It helps analyse and resolve the activities of herbal medicines. Group: Pharmaceutical. Alternative Names: β-D-Glucopyranoside, (3β,?16β)?-16,?28-dihydroxyoleana-11,?13(18)?-dien-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→4)?-O-[β-D-glucopyranosyl-(1→6)?]?-; (3β,16β)-16,28-Dihydroxyoleana-11,13(18)-dien-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside. CAS No. 91990-63-5. Pack Sizes: 20 mg. Product ID: B0005-479873. Molecular formula: C48H78O17. Mole weight: 927.12. Custom synthesis is available. Send your inquiries for more information.
London
Shikonin
Shikonin belongs naphthoquinone isolated from Arnebia sp. It is used as an anti-inflammatory treatment in traditional chinese medicine (TCM). It inhibits chemokine receptor function and suppresses HIV-1. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. Alternative Names: (±)-Alkannin; (±)-Shikalkin; (±)-Shikonin; (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone; 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-. CAS No. 54952-43-1. Pack Sizes: 100 mg. Product ID: B1370-094286. Molecular formula: C16H16O5. Mole weight: 288.29. Custom synthesis is available. Send your inquiries for more information.
London
tC°-CE Phosphoramidite
tC°-CE Phosphoramidite, a chemical reagent essential in oligonucleotide synthesis for biomedical applications, boasts a thermally cleavable protecting group enabling streamlined purification and deprotection of the end product. Its widespread usage extends to the creation of RNA and DNA probes, utilized regularly in the diagnosis and treatment of maladies such as cancer and viral infections. Group: Pharmaceutical. Alternative Names: 5'-O-(4,4'-Dimethoxytrityl)-1'-(1,3-diaza-2-oxophenoxazin-1-yl)-2'-deoxy-ß-D-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 201530-88-3. Pack Sizes: 1 g. Product ID: B1370-376546. Molecular formula: C45H50N5O8P. Mole weight: 819.88. Custom synthesis is available. Send your inquiries for more information.
London
TC-E3 5032
TC-E3 5032 is a linker used in PROTAC technology that can be used in the synthesis of HDAC6 and anaplastic lymphoma kinase (ALK) degraders. Group: Pharmaceutical. Alternative Names: E3 ligase Ligand 4; 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro-; Thalidomide 4-fluoride; Thalidomide fluoride; 4-Fluoro-thalidomide; Cereblon ligand 4;E3 ligase Ligand 4; 2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione. CAS No. 835616-60-9. Pack Sizes: 5 g. Product ID: BAT-006490. Molecular formula: C13H9FN2O4. Mole weight: 276.22. Custom synthesis is available. Send your inquiries for more information.
London
TCID
TCID is a DUB inhibitor for ubiquitin C-terminal hydrolase L3 with IC50 of 0.6 μM, 125-fold selective to L1. Group: Pharmaceutical. Alternative Names: 4,5,6,7-Tetrachloroindan-1,3-dione; UCH-L3 Inhibitor. CAS No. 30675-13-9. Pack Sizes: 100 mg. Product ID: B2693-089799. Molecular formula: C9H2Cl4O2. Mole weight: 283.92. Custom synthesis is available. Send your inquiries for more information.
London
Thiocholine iodide
Thiocholine iodide is an important hydrolyzed product of acetylthio-choline iodide and could be used and one of the substrates of Cholinesterase. Uses: For research used only. Group: Pharmaceutical. Alternative Names: (2-Mercaptoethyl)trimethylammonium iodide (7CI); Ammonium, (2-mercaptoethyl)trimethyl-, iodide (8CI); Ethanaminium, 2-mercapto-N,N,N-trimethyl-, iodide (9CI); Cholinethiol iodide; Thiocholine iodide; TChI. CAS No. 7161-73-1. Pack Sizes: 100 mg. Product ID: B0001-149809. Molecular formula: C5H14INS. Mole weight: 247.14. Custom synthesis is available. Send your inquiries for more information.
London
Vinpocetine
Vinpocetine is a Phosphodiesterase inhibitor and selective for PDE1. It also blocks voltage-gated Na+ channels. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Eburnamenine-14-carboxylic acid, ethyl ester, (3α,16α)-; (+)-Apovincaminic acid ethyl ester; (+)-cis-Apovincaminic acid ethyl ester; (+)-Vinpocetine; Apovincaminic acid ethyl ester; AY 27255; Bravinton; Cavinton; Ceractin; cis-Apovincaminic acid ethyl ester; Ethyl (+)-apovincaminate; Ethyl (+)-cis-apovincaminate; Ethyl apovincaminate; RGH 4405; TCV 3B; Ultra-Vinca; Vinporal. CAS No. 42971-09-5. Pack Sizes: 500 mg. Product ID: B0046-464044. Molecular formula: C22H26N2O2. Mole weight: 350.45. Custom synthesis is available. Send your inquiries for more information.