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| Product | Description | |
|---|---|---|
| Tacrolimus EP Impurity A | Ascomycin, isolated from Streptomyces, suppresses immune response in vitro with IC50 of 0.55 nM for mouse mixed lymphocyte. Uses: Anti-bacterial agents. Group: Pharmaceutical. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-ethyl-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; FK-520; FR900520; FR-900520; FR 900520; L 683590; L-683590; L683590; Changchuanmycin; Immunomycin; Ascomycin; Tacrolimus Related Compound A USP; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-. CAS No. 104987-12-4. Pack Sizes: 50 mg. Product ID: BBF-05774. Molecular formula: C43H69NO12. Mole weight: 792. Custom synthesis is available. Send your inquiries for more information. |  London |
| Tacrolimus EP Impurity C | Tacrolimus EP Impurity C is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,12,18-trimethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; 10-Desmethyl tacrolimus; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosin. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05742. Molecular formula: C43H67NO12. Mole weight: 789.99. Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrolimus EP Impurity D | Tacrolimus EP Impurity D is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (3S,4R,5S,8S,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; 8-epi Tacrolimus; 8-Epitacrolimus; Tacrolimus anhydrous 8-epimer; Tacrol. CAS No. 129212-35-7. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05771. Molecular formula: C44H69NO12. Mole weight: 804.04. Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrolimus EP Impurity E | Tacrolimus EP Impurity E is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-propyl-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; Dihydro Tacrolimus; Dihydro-FK 506; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotr. CAS No. 104987-30-6. Pack Sizes: 10 mg. Product ID: BBF-05773. Molecular formula: C44H71NO12. Mole weight: 806.06. Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrolimus EP Impurity G | Tacrolimus EP Impurity G is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-5,19-dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; Tacrolimus compound II; Tacrolimus anhydrous 19-epimer; 19-Epi FK-506; 1. CAS No. 144490-63-1. Pack Sizes: 10 mg. Product ID: BBF-05772. Molecular formula: C44H69NO12. Mole weight: 804.04. Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrolimus EP Impurity H | Tacrolimus EP Impurity H is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (1E,3S,4R,5S,8R,9E,12S,14S)-5-hydroxy-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-14-methoxy-14-[(2R,3S,5R)-3-methoxy-5-methyl-6-oxooxan-2-yl]-2,4,10,12-tetramethyl-7-oxo-8-(prop-2-en-1-yl)tetradeca-1,9-dien-3-yl (2S)-1-formylpiperidine-2-carboxylate; Tacrolimus monohydrate impurity H [EP]; 2-Piperidinecarboxylic acid, 1-formyl-, (1S,2R,3S,6R,7E,10S,12S)-3-hydroxy-1-[(1E)-2-[(1R,3R,4R)-4-hydroxy-. CAS No. 143210-33-7. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05744. Molecular formula: C43H69NO11. Mole weight: 776.01. Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrolimus EP Impurity I | Tacrolimus EP Impurity I is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (3S,4R,5E,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-19-hydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone; Tacrolimus diene; 23,24-Anhydro Tacrolimus; Δ23-FK-506; Tacrolimus Impurity I; T. CAS No. 104987-16-8. Pack Sizes: 25 mg. Product ID: BBF-05770. Molecular formula: C44H67NO11. Mole weight: 786.02. Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrolimus Hydroxy Acid Impurity | Tacrolimus Hydroxy Acid Impurity is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: Pyrido[2,1-c][1,4]oxaazacyclodocosine-19-carboxylic acid, 1,3,4,5,6,7,8,11,12,13,14,15,16,17,18,19,20,22,23,24,25,25a-docosahydro-5,15,19-trihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-1,7,20-trioxo-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,25aS)-; (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,25aS)-1,3,4,5,6,7,8,11,12,13,14,15,16,17,18,19,20,22,23,24,25,25a-Docosahydro-5,15,19-trihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-1,7,20-trioxo-8-(2-propen-1-yl)pyrido[2,1-c][1,4]oxaazacyclodocosine-19-carboxylic acid; Tacrolimus α-hydroxy acid; Tacrolimus hydroxy acid. CAS No. 1700657-83-5. Pack Sizes: 25 mg. Product ID: B1370-288687. Molecular formula: C44H71NO13. Mole weight: 822.06. Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrolimus Impurity (Methyl Acryl Aldehyde) | Tacrolimus Impurity (Methyl Acryl Aldehyde) is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (E)-3-[[(1R,3R,4R)-4-Hydroxy-3-methoxycyclohexyl]-2-methylacrylaldehyde; [1R-[1α(E),3α,4β]]-3-(4-Hydroxy-3-methoxycyclohexyl)-2-methyl-2-propenal; Tacrolimus Methylacryl Aldehyde; 3-((1R,3R,4R)-4-Hydroxy-3-methoxycyclohexyl)-2-methylacrylaldehyde, (E)-; (2E)-3-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-methylprop-2-enal; (2E)-3-[(1R,3R,4R)-4-Hydroxy-3-methoxycyclohexyl]-2-methylacrylaldehyde; 2-Propenal, 3-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-methyl-, (2E)-. CAS No. 109466-74-2. Pack Sizes: 1mg;1g;10g. Product ID: BBF-05775. Molecular formula: C11H18O3. Mole weight: 198.26. Custom synthesis is available. Send your inquiries for more information. | London |
| Tacrolimus monohydrate | Tacrolimus monohydrate is a potent immunosuppressive drug often administered to transplant recipient patients and exhibits a variety of adverse cardiovascular effects. Group: Pharmaceutical. Alternative Names: Tacrolimus Hydrate; Tsukubaenolide hydrate; (3S,?4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine?-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-hydrate. CAS No. 109581-93-3. Pack Sizes: 500 mg. Product ID: BBF-05727. Molecular formula: C44H71NO13. Mole weight: 822.03. Custom synthesis is available. Send your inquiries for more information. | London |
| 13-O-Desmethyl Tacrolimus | 13-O-Desmethyl Tacrolimus is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Group: Pharmaceutical. Alternative Names: (3S,4R,5S,8R,9E,12S,14S,15S,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26-Hexadecahydro-5,16,19-trihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14-methoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-16,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone. CAS No. 139958-51-3. Pack Sizes: 5 mg. Product ID: B1370-386089. Molecular formula: C43H67NO12. Mole weight: 789.99. Custom synthesis is available. Send your inquiries for more information. | London |
| Everolimus, Cyclosporine and Tacrolimus Mix Standard | Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation. Cyclosporine is an immunopsupressent thought to bind to cyclophilin in T-lymphocytes. Tacrolimus is also an immunosuppressant that blocks T-cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release. Group: Pharmaceutical. Pack Sizes: 1mg;1g;10g. Molecular formula: C53H83NO14/C62H111N11O12/C44H69N. Mole weight: 958.22/1202.61/612.02. Custom synthesis is available. Send your inquiries for more information. | London |
| Oxacyclohexane open ring tacrolimus | Oxacyclohexane open ring tacrolimus is an impurity of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Group: Pharmaceutical. Alternative Names: Tacrolimus Open Ring Impurity; Tacrolimus related compound, tacrolimus open ring; 3H-Pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,19,21(4H,8H,12H,23H)-tetrone, 5,6,11,13,14,15,16,17,18,20,24,25,26,26a-tetradecahydro-5,15,20,20-tetrahydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,26aS)-; (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,26aS)-5,6,11,13,14,15,16,17,18,20,24,25,26,26a-Tetradecahydro-5,15,20,20-tetrahydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,19,21(4H,8H,12H,23H)-tetrone; 3H-Pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,19,21(4H,8H,20H,23H)-tetrone, 5,6,11,12,13,14,15,16,17,18,24,25,26,26a-tetradecahydro-5,15,20,20-tetrahydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,26aR*]]-. CAS No. 144432-23-5. Pack Sizes: 5 mg. Product ID: BBF-05769. Molecular formula: C44H71NO13. Mole weight: 822.03. Custom synthesis is available. Send your inquirie | London |
| AP1903 | AP1903 is a lipid-permeable tacrolimus analogue with homodimerizing activity. Dimerizer drug AP1903 homodimerizes an analogue of human protein FKBP12 (Fv) which contains a single acid substitution (Phe36Val) so that AP1903 binds to wild-type FKBP12 with 1000-fold lower affinity. Group: Pharmaceutical. Alternative Names: AP1903; AP 1903; AP-1903; Rimiducid. CAS No. 195514-63-7. Pack Sizes: 50 mg. Product ID: B1370-462662. Molecular formula: C78H98N4O20. Mole weight: 1411.63. Custom synthesis is available. Send your inquiries for more information. | London |
| (E/Z)-FK-506 26,28-Allylic Ester Rearrangement Impurity | One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Group: Pharmaceutical. Alternative Names: Tacrolimus Impurity 2; Tacrolimus Regioisomer; Tacrolimus Allylic Ester Rearrangement Impurity. CAS No. 131944-48-4. Pack Sizes: 25 mg. Product ID: B1370-261446. Molecular formula: C44H69NO12. Mole weight: 804.02. Custom synthesis is available. Send your inquiries for more information. | London |
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