Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| Tacrine Impurities | Tacrine Impurities are crucial in the development and quality control of Alzheimer's disease treatments. Studying these impurities aids in enhancing the safety and efficacy of tacrine, an acetylcholinesterase inhibitor, crucial for symptom management in Alzheimer's, thus advancing therapeutic methods for neurodegenerative disorders. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Coluracetam | MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested. Group: Pharmaceutical. CAS No. 135463-81-9. Pack Sizes: 2 g. Product ID: B0084-083492. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Onitin | Onitin isolated from the herbs of Onychium japonicum. It shows super-oxide and DPPH free radical scavenging effects, and exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. Uses: Hepatoprotective activity. Group: Pharmaceutical. CAS No. 53823-02-2. Pack Sizes: 1 mg. Product ID: NP5547. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
