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| Product | Description | |
|---|---|---|
| 4,4'-Diaminodiphenylsulfone | Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and immunomodulatory effects. It is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects. It also inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase. Uses: Anti-inflammatory agent. Group: Pharmaceutical. CAS No. 80-08-0. Pack Sizes: 1 kg. Product ID: NP2822. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Acetone 2,4-Dinitrophenylhydrazone-[13C3] | Isotope labelled Acetone 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic ketone found in mainstream cigarette smoke. Acetone 2,4-Dinitrophenylhydrazone showed inhibitory activity towards soybean lipoxygenase and renal prostaglandin synthetase. Group: Pharmaceutical. CAS No. 395075-27-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003209. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetone 2,4-Dinitrophenylhydrazone-[d3] | Labelled Acetone 2,4-Dinitrophenylhydrazone. Acetone 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic ketone found in mainstream cigarette smoke. Acetone 2,4-Dinitrophenylhydrazone showed inhibitory activity towards soybean lipoxygenase and renal prostaglandin synthetase. Group: Pharmaceutical. CAS No. 259824-57-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-013535. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl-L-glutamic acid | A substrate for acetylglutamate kinase. An inhibitor of N-acetyl-L-glutamate synthetase. Group: Pharmaceutical. CAS No. 1188-37-0. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-003849. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Carglumic Acid | Carglumic Acid is an activator of carbamoyl phosphate synthetase 1 (CPS1). It inhibits cell proliferation of a variety of cancer cell lines with IC50 values ranging from 5 to 7.5 nM. Group: Pharmaceutical. CAS No. 1188-38-1. Pack Sizes: 1 kg. Product ID: BAT-016472. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glutathione EP Impurity D | Glutathione EP Impurity D is a substrate used for the biosynthesis of L-glutathione by glutathione synthetase. It is used to study the active sites and kinetics of glutathione synthestase(s). It is also used in biological studies for the detection of thiols. Group: Pharmaceutical. CAS No. 636-58-8. Pack Sizes: 1 g. Product ID: BAT-015930. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Halofuginone lactate | Halofuginone lactate is a halogenated derivative of febrifugine. Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM. Group: Pharmaceutical. CAS No. 82186-71-8. Pack Sizes: 250 mg. Product ID: B2692-136247. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mupirocin | Mupirocin is an isoleucyl t-RNA synthetase inhibitor, used in the treatment of bacterial skin infections. Group: Pharmaceutical. CAS No. 12650-69-0. Pack Sizes: 200 mg. Product ID: BBF-03814. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-(2-methyl-4-oxopentan-2-yl)-sulfamethoxazole | An impurity of Sulfamethoxazole, which is an antibiotic and a structural analog of para-aminobenzoic acid (PABA). It competes with PABA to bind to dihydropteroate synthetase to inhibit the synthesis of dihydrofolic acid. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: B1658-254050. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| RTA-408 | RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Group: Pharmaceutical. CAS No. 1474034-05-3. Pack Sizes: 20 mg. Product ID: B0084-462776. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sulfamethizole-[d4] | An isotope labelled Sulfamethizole. Sulfamethizole is a sulfonamide antibiotic. It competes with PABA to bind to dihydropteroate synthetase to inhibit the synthesis of dihydrofolic acid. Group: Pharmaceutical. CAS No. 2470130-12-0. Pack Sizes: 10 mg. Product ID: BLP-013900. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sulfamethoxazole-[d4] | Sulfamethoxazole-[d4] is the labelled analogue of Sulfamethoxazole. Sulfamethoxazole is an antibiotic and a structural analog of para-aminobenzoic acid (PABA). It competes with PABA to bind to dihydropteroate synthetase to inhibit the synthesis of dihydrofolic acid. Group: Pharmaceutical. CAS No. 1020719-86-1. Pack Sizes: 10 mg. Product ID: BLP-012599. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sulfamethoxazole-[ring-13C6] | An isotope labelled Sulfamethoxazole. Sulfamethoxazole is an antibiotic and a structural analog of para-aminobenzoic acid (PABA). It competes with PABA to bind to dihydropteroate synthetase to inhibit the synthesis of dihydrofolic acid. Group: Pharmaceutical. CAS No. 1196157-90-0. Pack Sizes: 10 mg. Product ID: BLP-009103. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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