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Avasopasem manganese is a superoxide dismutase mimetic drug candidate. This drug has potential application for radiation-induced esophagitis and oral mucositis, in addition to being currently tested against COVID-19. Group: Pharmaceutical. Alternative Names: GC-4419; GC4419; GC 4419; M 40419; M40419; M-40419. CAS No. 435327-40-5. Pack Sizes: 1mg;1g;10g. Product ID: 435327-40-5. Molecular formula: C21H35Cl2MnN5. Mole weight: 483.38. Custom synthesis is available. Send your inquiries for more information.
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CORM-3
CORM-3 is a water-soluble carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. It attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels. Group: Pharmaceutical. Alternative Names: Tricarbonylchloro(glycinato)ruthenium; (OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium; CORM3; CORM 3. CAS No. 475473-26-8. Pack Sizes: 50 mg. Product ID: B0084-463459. Molecular formula: C5H4ClNO5Ru. Mole weight: 294.61. Custom synthesis is available. Send your inquiries for more information.
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EUK 134
EUK-134 is a unique small molecule antioxidant and anti-aging active substance with excellent antioxidant properties. It possesses the dual effects of superoxide dismutase SOD and catalase CAT, effectively improving cell damage caused by oxidative stress, and inhibiting the formation of β-amyloid protein and related amyloid protein fibers. The EUK-134 facilitates the penetration and absorption of the skin surface, enabling direct entry into the skin to exert its effects and optimize its potent efficacy. Essentially functioning as a catalyst, it remains unaffected by the number of reactions, allowing for reusability with minimal quantity while maintaining stability in nature. It can be used in anti-aging products, sunscreen products, whitening products and skin repair products. Group: Pharmaceutical. Alternative Names: Manganese, chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]](2-)]-, (SP-5-13)-; (SP-5-13)-Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]](2-)]manganese; Manganese, chloro[[2,2'-[1,2-ethanediylbis(nitrilomethylidyne)]bis[6-methoxyphenolato]](2-)-N2,N2',O1,O1']-; Phenol, 2,2'-[1,2-ethanediylbis(nitrilomethylidyne)]bis[6-methoxy-. CAS No. 81065-76-1. Pack Sizes: 100 mg. Product ID: B2693-098846. Molecular formula: C18H18ClMnN2O4. Mole weight: 416.74. Custom synthesis is available. Send your inquiries for more informatio
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Imisopasem manganese
Imisopasem manganese is a manganese-based non-peptidyl mimetic of the human mitochondrial manganese superoxide dismutase (MnSOD), with potential antioxidant and chemo/radioprotective activities. Upon administration, imisopasem manganese mimics the activity of MnSOD and scavenges reactive oxygen species (ROS), such as superoxide anion, which prevents oxygen free radical damage to macromolecules such as DNA. Group: Pharmaceutical. Alternative Names: M40403; M 40403; M 40403; CG4419; CG 4419; CG-4419; SC-72325; SC72325; SC 72325. CAS No. 218791-21-0. Pack Sizes: 10 mg. Product ID: B0084-102510. Molecular formula: C21H35Cl2MnN5. Mole weight: 483.39. Custom synthesis is available. Send your inquiries for more information.
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Loganin
Loganin is isolated from the fruits of Cornus officinalis Sieb. et Zucc. It reduced malondialdehyde and increased superoxide dismutase in serum and kidney. It has great promise for the treatment of diabetic complications. Uses: Anti-inflammatory and anti-oxidant. Group: Pharmaceutical. Alternative Names: 7-Hydroxy-6-desoxyverbenalin; Loganoside. CAS No. 18524-94-2. Pack Sizes: 100 mg. Product ID: BBF-01825. Molecular formula: C17H26O10. Mole weight: 390.39. Custom synthesis is available. Send your inquiries for more information.
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p-Phlorizin
Trilobatin, coming from the herbs of Lithocarpus pachyphyllus, potentially inhibits the LPS-induced inflammatory response by suppressing the NF-κB signaling pathway. It increased superoxide dismutase (SOD) activity. Besides, Trilobatin is a potential effective α-glucosidase inhibitor for management of postprandial hyperglycemia with less side effect. Uses: Anti-inflammatory. Group: Pharmaceutical. Alternative Names: 1-[4-(β-D-Glucopyranosyloxy)-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone; p-Phloridzin; Phloretin 4'-glucoside; Phloretin 4'-β-D-glucoside; Phloretin-4-O-glycoside; Phloretin-4'-O-β-D-glucopyranoside; Phloretine-4'-glucoside; Prunin dihydrochalcone; Trilobatin. CAS No. 4192-90-9. Pack Sizes: 20 mg. Product ID: NP0949. Molecular formula: C21H24O10. Mole weight: 436.41. Custom synthesis is available. Send your inquiries for more information.
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RTA-408
RTA-408 is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2, Nfe2l2), with potential chemopreventive activity. Upon administration, RTA 408 activates the cytoprotective transcription factor Nrf2. In turn, Nrf2 translocates to the nucleus, dimerizes with a small Maf protein (sMaf), and binds to the antioxidant response element (ARE). This induces the expression of a number of cytoprotective genes, including NAD(P)H quinone oxidoreductase 1 (NQO1), sulfiredoxin 1 (Srxn1), heme oxygenase-1 (HO1, HMOX1), superoxide dismutase 1 (SOD1), gamma-glutamylcysteine synthetase (gamma-GCS), thioredoxin reductase-1 (TXNRD1), glutathione S-transferase (GST), glutamate-cysteine ligase catalytic subunit (Gclc) and glutamate-cysteine ligase regulatory subunit (Gclm), and increases the synthesis of the antioxidant glutathione (GSH). Nrf2, a leucine zipper transcription factor, plays a key role in the maintenance of redox balance and cytoprotection against oxidative stress. Group: Pharmaceutical. Alternative Names: RTA408; RTA408; RTA-408. Omaveloxolone; Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-. CAS No. 1474034-05-3. Pack Sizes: 20 mg. Product ID: B0084-462776. Molecular formula: C33H44F2N2O3. Mole weight: 554.723. Custom synthesis is available. Send your inquiries for more information.
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Taraxerone
Taraxerone is isolated from the herb of Taraxacum mongolicum Hand. Mazz. It can prevent catalase and superoxide dismutase, and reduce glutathione concentration. Group: Pharmaceutical. Alternative Names: D-Friedoolean-14-en-3-one;Taraxera-14-ene-3-one;Taraxeron;27-Norolean-14-en-3-one,13-methyl-, (13a)-;Tarxerone;27-Norolean-14-en-3-one, 13-methyl-, (13α)-. CAS No. 514-07-8. Pack Sizes: 20 mg. Product ID: NP6262. Molecular formula: C30H48O. Mole weight: 424.7. Custom synthesis is available. Send your inquiries for more information.
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