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| Product | Description | |
|---|---|---|
| α-Melanocyte-Stimulating Hormone (MSH), amide | α-Melanocyte-Stimulating Hormone (MSH), is an endogenous melanocortin receptor agonist that results in the activation of adenylyl cyclase, with anti-inflammatory effect. Group: Pharmaceutical. Alternative Names: CZEN-002; CZEN002; CZEN 002; α-MSH; α-MSH, amide; α-Melanotropin; α-Melanocyte stimulating hormone. CAS No. 581-05-5. Pack Sizes: 10 mg. Product ID: BAT-006107. Molecular formula: C77H109N21O19S. Mole weight: 1637.88. Custom synthesis is available. Send your inquiries for more information. |  London |
| 4,4'-DIHYDROXY-2-METHOXYCHALCONE | Echinatin is extracted from the root of Glycyrrhiza glabra L. It inhibits DNP-ATPase activity while stimulating range latent ATPase activity in the low concentration. It disturbs the mitochondrial energy transfer reactions and membrane permeability. It was demonstrated to inhibit the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. Group: Pharmaceutical. Alternative Names: (E)-3-(4-Hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one; (E)-4,4'-Dihydroxy-2-methoxychalcone; 4,4'-Dihydroxy-2-methoxy-trans-chalcone; 4'-Dihydroxy-2-Methoxychalcone; Retrochalcone. CAS No. 34221-41-5. Pack Sizes: 10 mg. Product ID: NP0936. Molecular formula: C16H14O4. Mole weight: 270.28. Custom synthesis is available. Send your inquiries for more information. | London |
| AA92593 | AA92593 is a selective and competitive OPN4 (melanopsin) antagonist. It blocks melanopsin activity and stimulates α-melanocyte-stimulating hormone (α-MSH) expression and induces melanin distribution in the melanophores, which darkens the embryo. Group: Pharmaceutical. Alternative Names: 1-((4-Methoxy-3-methylphenyl)sulfonyl)piperidine. CAS No. 457961-34-1. Pack Sizes: 1mg;1g;10g. Product ID: 457961-34-1. Molecular formula: C13H19NO3S. Mole weight: 269.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Group: Pharmaceutical. Alternative Names: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. CAS No. 183552-38-7. Pack Sizes: 10 mg. Product ID: BAT-006166. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Hexapeptide-1 | Acetyl Hexapeptide-1, also known as Melitane, is a biomimetic peptide antagonist of the α-MSH (α-Melanocyte-Stimulating Hormone). It stimulates tyrosinase activity, melanin synthesis and melanocyte dendricity, and protects DNA damage caused by UV exposure. Group: Pharmaceutical. Alternative Names: L-Tryptophanamide, N-acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-; N-Acetyl-L-norleucyl-L-alanyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophanamide; Acetyl hexapeptide 1; Melitane; Melitane GL; Melitane GL 200; Ac-Nle-Ala-His-D-Phe-Arg-Trp-NH2. CAS No. 448944-47-6. Pack Sizes: 5 mg. Product ID: BAT-006234. Molecular formula: C43H59N13O7. Mole weight: 870.01. Custom synthesis is available. Send your inquiries for more information. | London |
| Alarelin diacetate | Alarelin acetate is a synthetic Gonadotrophin-releasing hormone agonist. It is the acetate form of a hypothalamic peptide. It is a potent LH-RH agonist in rats and mice. It reversibly delays sexual maturation in rats, stimulates spawning activity in fish. It could inducte ovulation and is used to treat endmometriosis. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Uses: Alarelin acetate could inducte ovulation and is used to treat endmometriosis. it is responsible for the secretion of gonadotropins, luteinizing hormone (lh) and follicle-stimulating hormone (fsh), from the pituitary glands. Group: Pharmaceutical. Alternative Names: 1-9-Luteinizing hormone-releasing factor (swine), 6-D-alanine-9-(N-ethyl-L-prolinamide)-, acetate (1:2); 1-9-Luteinizing hormone-releasing factor (swine), 6-D-alanine-9-(N-ethyl-L-prolinamide)-, diacetate (salt); Luteinizing hormone-releasing factor (pig), 6-D-alanine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-, diacetate (salt); Alarelin acetate; H-Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt.2C2H4. CAS No. 79561-22-1. Pack Sizes: 100 mg. Product ID: BAT-010030. Molecular formula: C60H86N16O16. Mole weight: 1287.42. Custom synthesis is available. Send your inquiries for more information. | London |
| Almitrine dimesylate | Almitrine dimesylate is the dimethanesulfonate salt of almitrine. It acts as an agonist of peripheral chemoreceptors located on the carotid bodies, thereby stimulating respiratory system. Group: Pharmaceutical. Alternative Names: Almitrine mesylate; Almitrine bismesylate; Almitrine dimethanesulfonate; Vectarion. CAS No. 29608-49-9. Pack Sizes: 20 g. Product ID: B0084-089581. Molecular formula: C26H29F2N7.2(CH4O3S). Mole weight: 669.764. Custom synthesis is available. Send your inquiries for more information. | London |
| Anamorelin Fumarate | Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. Group: Pharmaceutical. Alternative Names: RC-1291 Fumarate; ONO-7643 Fumarate; RC1291 Fumarate; ONO7643 Fumarate; RC 1291 Fumarate; ONO 7643 Fumarate. CAS No. 339539-92-3. Pack Sizes: 50 mg. Product ID: B0084-463631. Molecular formula: C35H46N6O7. Mole weight: 662.78. Custom synthesis is available. Send your inquiries for more information. | London |
| Anamorelin HCl | Anamorelin, also known as RC-1291 or ONO-7643, is the orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Uses: For research used only. Group: Pharmaceutical. Alternative Names: RC 1291; RC1291; RC-1291; RC 1291 HCl; ONO-7643; ONO7643; ONO 7643; Anamorelin hydrochloride. CAS No. 861998-00-7. Pack Sizes: 100 mg. Product ID: B0084-462661. Molecular formula: C31H43ClN6O3. Mole weight: 583.174. Custom synthesis is available. Send your inquiries for more information. | London |
| Bemcentinib | Bemcentinib is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer. The receptor tyrosine kinase Axl may play an important role in cancer progression, invasion, metastasis, drug resistance, and patient mortality. R428 inhibits Axl with low nanomolar activity and blocked Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Pharmacologic investigations revealed favorable exposure after oral administration such that R428-treated tumors displayed a dose-dependent reduction in expression of the cytokine granulocyte macrophage colony-stimulating factor and the epithelial-mesenchymal transition transcriptional regulator Snail. In support of an earlier study, R428 inhibited angiogenesis in corneal micropocket and tumor models. R428 administration reduced metastatic burden and extended survival in MDA-MB-231 intracardiac and 4T1 orthotopic (median survival, >80 days compared with 52 days; P < 0.05) mouse models of breast cancer metastasis. Additionally, R428 synergized with cisplatin to enhance suppression of liver micrometastasis. Our results show that Axl signaling regulates breast cancer metastasis at multiple levels in tumor cells and tumor stromal cells and that selective Axl blockade confers therapeutic value in prolonging survival of animals bearing metast | London |
| β-MSH (human) | β-MSH (human) is a melanocortin (MC) receptor agonist. Group: Pharmaceutical. Alternative Names: Beta-MSH (1-22) (human); β-Melanocyte Stimulating Hormone (MSH), human; b-Melanotropin (human); ALA-GLU-LYS-LYS-ASP-GLU-GLY-PRO-TYR-ARG-MET-GLU-HIS-PHE-ARG-TRP-GLY-SER-PRO-PRO-LYS-ASP; Melanocyte stimulating hormone, beta-human; H-ALA-GLU-LYS-LYS-ASP-GLU-GLY-PRO-TYR-ARG-MET-GLU-HIS-PHE-ARG-TRP-GLY-SER-PRO-PRO-LYS-ASP-OH. CAS No. 17908-57-5. Pack Sizes: 5 mg. Product ID: BAT-006186. Molecular formula: C118H174N34O35S. Mole weight: 2660.94. Custom synthesis is available. Send your inquiries for more information. | London |
| Bremelanotide | Bremelanotide is a peptide melanocortin receptor agonist developed for the treatment of sexual dysfunction, hemorrhagic shock and reperfusion injury. Uses: Bremelanotide is a synthetic peptide drug that has generated a lot of interest in the drug development community due to its potential applications in sexual dysfunction and other conditions. this peptide is a synthetic analog of the natural hormone alpha-msh (melanocyte stimulating hormone) and acts as a non-selective agonist of the melanocortin receptors mc3-r and mc4-r. one of the main areas of. Group: Pharmaceutical. Alternative Names: (Ac-Nle4, Asp5, D-Phe7, Lys10)-cyclo-α-MSH (4-10); PT 141; PT-141; PT141. CAS No. 189691-06-3. Pack Sizes: 10 mg. Product ID: BAT-010024. Molecular formula: C50H68N14O10. Mole weight: 1025.16. Custom synthesis is available. Send your inquiries for more information. | London |
| Chitosan | Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Deacetylated chitin; Poly(D-glucosamine); Poly-b-(1,4)-2-Amino-2-deoxy-D-glucose; 2-Amino-2-deoxy-(1,4)-b-D-glucopyranan; deacetylchitin; b-1,4-poly-D-glucosamine; poly-D-glucosamine; poly-(1,4-b-D-glucopyranosamine). CAS No. 9012-76-4. Pack Sizes: 1kg. Product ID: B1370-187887. Molecular formula: [C7H15NO4]n. Mole weight: 60-120 kDa. Custom synthesis is available. Send your inquiries for more information. | London |
| Degarelix acetate hydrate | Degarelix acetate is a synthetic peptide that acts as a gonadotrophin-releasing hormone (GnRH) antagonist. Degarelix targets GnRH receptors in the pituitary gland, resulting in reduction of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and suppression of testosterone. Group: Pharmaceutical. Alternative Names: FE-200486; FE 200486; FE200486; ASP-3550; ASP 3550; ASP3550. CAS No. 934246-14-7. Pack Sizes: 100 mg. Product ID: BAT-010777. Molecular formula: C84H109ClN18O19. Mole weight: 1710.32. Custom synthesis is available. Send your inquiries for more information. | London |
| Deoxycholic acid | Deoxycholic acid is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. Deoxycholic acid is specifically responsible for activating the G-protein-coupled bile acid receptor TGR5, stimulating the thermogenic activity of brown adipose tissue (BAT). Uses: Hypotensive. Group: Pharmaceutical. Alternative Names: Cholanoic Acid; Desoxycholic acid; 3α,12α-dihydroxy-5β-cholanate; Deoxycholate; Cholerebic; Degalol; Droxolan; Pyrochol; 5β-cholanic acid-3α,12α-diol; 7-Deoxycholic acid; 5β-Deoxycholic Acid; NSC 8797; Septocholl; Ursodeoxycholic Acid EP Impurity E. CAS No. 83-44-3. Pack Sizes: 250 g. Product ID: NP6088. Molecular formula: C24H40O4. Mole weight: 392.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Filgrastim | Filgrastim is a recombinant human granulocyte colony stimulating factor (G-CSF). Under the brand name Neupogen, it was approved for the treatment of low blood neutrophils. Group: Pharmaceutical. Alternative Names: Granulocyte colony-stimulating factor; rhG-CSF. CAS No. 143011-72-7. Pack Sizes: 1mg;1g;10g. Product ID: 143011-72-7. Molecular formula: C845H1343N223O243S9. Mole weight: 18802.8. Custom synthesis is available. Send your inquiries for more information. | London |
| FSL-1 TFA salt | FSL-1 is a TLR2/6 peptide agonist (also a putative TLR10 ligand) that activates NF-κB. FSL-1 induces the expression of some pro-inflammatory cytokines such as IL-8, IL-1β, CCL20 and TNF-α in vitro. Group: Pharmaceutical. Alternative Names: FSL 1 TFA salt; FSL1 TFA salt; L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-, 2,2,2-trifluoroacetic acid; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine 2,2,2-trifluoroacetic acid; FSL-1 lipoprotein, synthetic TFA salt; Fibroblast-stimulating lipopeptide-1 TFA salt; Pam2-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH TFA. Pack Sizes: 5 mg. Product ID: B1370-425891. Molecular formula: C86H141F3N14O20S. Mole weight: 1780.18. Custom synthesis is available. Send your inquiries for more information. | London |
| Gliclazide EP Impurity B | An impurity of Gliclazide. Gliclazide is a second-generation sulfonylurea oral antidiabetic medication primarily used to treat type 2 diabetes by stimulating insulin secretion from pancreatic beta cells and reducing hepatic glucose production. Group: Pharmaceutical. Alternative Names: N-Nitroso gliclazide impurity B; Gliclazide Impurity B; 2-Nitroso-octahydrocyclopenta[c]pyrrole; Octahydro-2-nitrosocyclopenta[c]pyrrole; N-Nitroso-3-azabicyclo[3.3.0]octane; 3-Nitroso-3-azabicyclo[3.3.0]octane; N-Nitroso Gliclazide EP Impurity B. CAS No. 54786-86-6. Pack Sizes: 100 mg. Product ID: B1370-440025. Molecular formula: C7H12N2O. Mole weight: 140.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Glimepiride | Glimepiride is a medium to long-acting sulfonylurea antidiabetic drug. It acts by stimulating the insulin release from pancreatic β-cells and decreases glucose output from the liver. Group: Pharmaceutical. Alternative Names: Amaryl; Glimepirid; Amarel; HOE 490; 1-[[p-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea. CAS No. 93479-97-1. Pack Sizes: 10 g. Product ID: NP3448. Molecular formula: C24H34N4O5S. Mole weight: 490.62. Custom synthesis is available. Send your inquiries for more information. | London |
| Golotimod | Golotimod is an orally bioactive synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and antineoplastic activities. Golotimod has been shown to inhibit the expression of STAT-3, reversing immunosuppression and stimulating an anti-tumor immune response. It may stimulate the production of T-lymphocytes (in particular the helper T [Th1] cells), activate macrophages, and increase levels of interleukin 2 and interferon gamma. Group: Pharmaceutical. Alternative Names: SCV-07; Gamma-D-Glu-L-trp; SCV07; SCV 07; Gamma-D-Glutamyl-L-tryptophan; (2R)-2-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid. CAS No. 229305-39-9. Pack Sizes: 50 mg. Product ID: BAT-010153. Molecular formula: C16H19N3O5. Mole weight: 333.34. Custom synthesis is available. Send your inquiries for more information. | London |
| Hesperetin | Hesperetin, a flavonoid widely found in citrus, is also one of the vitamin Ps that the human body is generally prone to lack. Study showed that it promoted osteogenic differentiation of human mesenchymal stem cells in vitro. Hesperetin can be used in health products. Hesperetin has an antioxidant effect, reduces the production of free radicals, plays an anti-aging role and removes wrinkles. It can also enhance the homeostasis of epidermal osmotic barrier by stimulating epidermal proliferation and differentiation, so as to repair the skin barrier. In addition, hesperetin has whitening and lightening spots, brightening skin, removing dark circles, anti-inflammatory and antibacterial, hair care and many other effects. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Hesperitin; 3',5,7-Trihydroxy-4'-methoxyflavanone; Hesperin; (2S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)-; Flavanone, 3',5,7-trihydroxy-4'-methoxy-; (-)-Hesperetin; (S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 5,7,3'-Trihydroxy-4'-methoxyflavanone; Eriodictyol 4'-monomethyl ether; NSC 57654; TCI-CA 05. CAS No. 520-33-2. Pack Sizes: 50 g. Product ID: NP1882. Molecular formula: C16H14O6. Mole weight: 302.28. Custom synthesis is available. Send your inquiries for more informat | London |
| Hesperidin | Hesperidin is a flavonoid substance widely present in the peel of Citrus sinensis, and is also one of the vitamin P that the human body is generally easy to lack. Hesperidin has an antioxidant effect, reduces the generation of free radicals, and plays a role in anti-aging and wrinkling. It can also enhance the homeostasis of the epidermal osmotic barrier by stimulating epidermal proliferation and differentiation, to repair the skin barrier. In addition, hesperidin also has whitening and lightening spots, brightening skin, removing dark circles, anti-inflammatory and antibacterial, hair care, and many other effects. Uses: Anti-inflammatory; analgesic; antioxidant; anticarcinogenic effect. Group: Pharmaceutical. Alternative Names: 3,5,7-Trihydroxy-4-methoxyflavanone-7-O-(6-O-a-L-rhamnopyranosyl)-b-D-glucopyranoside; Hesperetin-7-rutinoside; Cirmtin; (2S)-7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-. CAS No. 520-26-3. Pack Sizes: 2 kg. Product ID: NP2550. Molecular formula: C28H34O15. Mole weight: 610.56. Custom synthesis is available. Send your inquiries for more information. | London |
| LHRH (free acid) | LHRH (free acid), also known as Luteinizing Hormone-Releasing Hormone free acid, is a neuropeptide that plays a crucial role in regulating reproduction. This hormone is secreted by the hypothalamus and acts on the anterior pituitary gland to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are essential for reproductive functions. Group: Pharmaceutical. Alternative Names: Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly; H-Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-OH; 10-Glycine-luteinizing hormone-releasing factor (swine); 10-Glycine-luteinizing hormone-releasing factor (pig); 10-Glycine-LH-RH; [Gly-OH10]-LHRH; LH-RH(OH); LHRH acid; PGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly; LHRH free acid; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-glycyl-L-leucyl-L-arginyl-L-prolyl-glycine; XHWSYGLRPG. CAS No. 35263-73-1. Pack Sizes: 1mg;1g;10g. Product ID: BAT-015735. Molecular formula: C55H74N16O14. Mole weight: 1183.27. Custom synthesis is available. Send your inquiries for more information. | London |
| Melanostatin DM | Melanostatin DM is an inhibitor of α-melanocyte stimulating hormone (α-MSH). It is used in cosmetics as a whitening agent. Group: Pharmaceutical. Alternative Names: Haatpln; Histidyl-arginyl-alanyl-tryptophyl-phenylalanyl-lysinamide. CAS No. 123689-72-5. Pack Sizes: 5 mg. Product ID: BAT-006230. Molecular formula: C41H58N14O6. Mole weight: 842.99. Custom synthesis is available. Send your inquiries for more information. | London |
| Melanotan I | A synthetic analogue of α-melanocyte stimulating hormone (α-MSH). Group: Pharmaceutical. Alternative Names: Afamelanotide acetate; (Nle4,D-Phe7)-α-MSH; NDP-MSH. CAS No. 75921-69-6. Pack Sizes: 10 mg. Product ID: BAT-010533. Molecular formula: C78H111N21O19. Mole weight: 1646.85. Custom synthesis is available. Send your inquiries for more information. | London |
| Mianserin Hydrochloride | Mianserin Hydrochloride is a psychoactive drug of the tetracyclic antidepressant.It is classified as a noradrenergic and specific serotonergic antidepressant (NaSSA) and has antidepressant, anxiolytic (anti-anxiety), hypnotic (sedating), antiemetic (nausea and vomiting-attenuating), orexigenic (appetite-stimulating), and antihistamine effects.It is not approved for use in the US. Uses: Antidepressive agents, second-generation. Group: Pharmaceutical. Alternative Names: ORG GB-94 HCl; Mianserin hydrochloride; Tolvon; Tolvin; ORG GB 94; Lerivon. CAS No. 21535-47-7. Pack Sizes: 10 g. Product ID: B2693-062932. Molecular formula: C18H20N2.HCl. Mole weight: 300.83. Custom synthesis is available. Send your inquiries for more information. | London |
| Oclacitinib | Oclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC50 's ranging from 36 to 249 nm. Oclacitinib had minimal effects on cytokines that did not activate the JAK1 enzyme in cells (erythropoietin, granulocyte/macrophage colony-stimulating factor, IL-12, IL-23; IC50 's > 1000 nm). These results demonstrate that oclacitinib is a targeted therapy that selectively inhibits JAK1-dependent cytokines involved in allergy, inflammation, and pruritus and suggests these are the mechanisms by which oclacitinib effectively controls clinical signs associated with allergic skin disease in dogs. Group: Pharmaceutical. Alternative Names: Cyclohexanemethanesulfonamide, N-methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-, trans-; trans-N-Methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanemethanesulfonamide; JAKi; PF 03394197. CAS No. 1208319-26-9. Pack Sizes: 50 mg. Product ID: B0084-462291. Molecular formula: C15H23N5O2S. Mole weight: 337.44. Custom synthesis | London |
| Palmitoyl Tetrapeptide-3 | Palmitoyl tetrapeptide-3 is a synthetic peptide used for skin care and anti-aging cosmetics. Palmitoyl tetrapeptide 3 corresponds to the 341-344 amino acid sequence of the heavy chain of human immunoglobulin, which has the effect of stimulating phagocytosis. Group: Pharmaceutical. Alternative Names: Rigin; palmitoyl-Gly-Gln-Pro-Arg-OH; Palm-GQPR; N-palmitoyl-glycyl-L-glutaminyl-L-prolyl-L-arginine; Palmitoyl tetrapeptide-7; N-Palmitoylrigin. CAS No. 221227-05-0. Pack Sizes: 2 g. Product ID: BAT-010581. Molecular formula: C34H62N8O7. Mole weight: 694.91. Custom synthesis is available. Send your inquiries for more information. | London |
| PD-173955 | PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth. PD173955 showed cell cycle arrest in G(1). PD173955 has an IC(50) of 1-2 nM in kinase inhibition assays of Bcr-Abl, and in cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 inhibited kit ligand-dependent c-kit autophosphorylation (IC(50) = approximately 25 nM) and kit ligand-dependent proliferation of M07e cells (IC(50) = 40 nM) but had a lesser effect on interleukin 3-dependent (IC(50) = 250 nM) or granulocyte macrophage colony-stimulating factor (IC(50) = 1 microM)-dependent cell growth. Group: Pharmaceutical. Alternative Names: PD173955; PD 173955; PD-173955. CAS No. 260415-63-2. Pack Sizes: 10 mg. Product ID: B0084-088782. Molecular formula: C21H16Cl2N4OS. Mole weight: 443.35. Custom synthesis is available. Send your inquiries for more information. | London |
| Repaglinide | Repaglinide is a potassium channel blocker, which lowers blood glucose by stimulating the release of insulin from the pancreas, used for the treatment of type II diabetes. Group: Pharmaceutical. Alternative Names: AG-EE 388 ZW; AG-EE388 ZW; AG-EE-388 ZW; AG-EE 623 ZW; AG-EE623 ZW, AG-EE-623 ZW; Prandin; GlucoNorm; Surepost; NovoNorm. CAS No. 135062-02-1. Pack Sizes: 1 g. Product ID: NP3248. Molecular formula: C27H36N2O4. Mole weight: 452.59. Custom synthesis is available. Send your inquiries for more information. | London |
| Sodium Picosulfate | Sodium Picosulfate is a stimulant laxative that works by stimulating the smooth muscles of the intestines to enhance peristalsis and inhibit the absorption of water and electrolytes in the bowel. This action helps to soften the stool and facilitate its passage. It is commonly used for treating constipation, aiding bowel movements after surgery, and preparing the bowel for procedures such as colonoscopy or X-ray examinations. Uses: Cathartics. Group: Pharmaceutical. Alternative Names: Picosulfate sodium; Laxoberon; Neopax; Evacuol; Guttalax; Rapilax; 4,4'-(2-Picolylidene)bis(phenylsulfuric acid) disodium salt; 2-Picolylidenebis(p-phenyl sodium sulfate); 4,4'-(2-Pyridylmethylene)diphenol bis(hydrogen sulfate) disodium salt; Disodium 4,4'-disulfoxydiphenyl-(2-pyridyl)methane. CAS No. 10040-45-6. Pack Sizes: 25 g. Product ID: B1370-052784. Molecular formula: C18H13NNa2O8S2. Mole weight: 481.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Talabostat mesylate | Talabostat mesylate is the orally bioavailable mesylate salt of an amino boronic dipeptide with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines. Uses: For research used only. Group: Pharmaceutical. Alternative Names: (R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-ylboronic acid methanesulfonic acid (1:1); PT-100; PT100; PT 100; D05989; D-05989; D 05989; Val-boro-pro; Talabostat. CAS No. 150080-09-4. Pack Sizes: 20 mg. Product ID: B0084-084554. Molecular formula: C10H23BN2O6S. Mole weight: 310.17. Custom synthesis is available. Send your inquiries for more information. | London |
| Taltirelin | Taltirelin is a thyrotropin-releasing hormone receptor (TRH-R) superagonist with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release). Group: Pharmaceutical. Alternative Names: N-[[(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl]carbonyl]-L-histidyl-L-prolinamide; (S)-N-[(Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-L-prolinamide; (4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-prolinamide; Ceredist; TA 0910; (S)-N-((S)-1-((S)-2-Carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxamide; 1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide. CAS No. 103300-74-9. Pack Sizes: 1mg;1g;10g. Product ID: BAT-010055. Molecular formula: C17H23N7O5. Mole weight: 405.41. Custom synthesis is available. Send your inquiries for more information. | London |
| Taltirelin Hydrate | Taltirelin hydrate is a thyrotropin-releasing hormone receptor (TRH-R) superagonist with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release). Uses: Nootropic agents. Group: Pharmaceutical. Alternative Names: N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide tetrahydrate; (S)-N-[(Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-L-prolinamide tetrahydrate; Ceredist tetrahydrate; TA 0910 tetrahydrate; (S)-N-((S)-1-((S)-2-Carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxamide tetrahydrate; 1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide tetrahydrate. CAS No. 201677-75-0. Pack Sizes: 1mg;1g;10g. Product ID: BAT-010056. Molecular formula: C17H31N7O9. Mole weight: 477.46. Custom synthesis is available. Send your inquiries for more information. | London |
| 1,4-Dihydro-1-methyl-4-oxonicotinamide | A metabolite of Nicotine,which is a potent parasympathomimetic stimulant. Group: Pharmaceutical. Alternative Names: 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide. CAS No. 769-49-3. Pack Sizes: 1mg;1g;10g. Product ID: NP0612. Molecular formula: C7H8N2O2. Mole weight: 152.15. Custom synthesis is available. Send your inquiries for more information. | London |
| (1'S,2'S)-Nicotine-1'-Oxide-[d3] | A metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Group: Pharmaceutical. Alternative Names: (1'S,2'S)-Nicotine-1'-Oxide-d3. Pack Sizes: 10 mg. Product ID: BLP-014878. Molecular formula: C10H11D3N2O. Mole weight: 181.25. Custom synthesis is available. Send your inquiries for more information. | London |
| 2',3'-cGAMP | 2',3'-cGAMP was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. It can activate innate immunity by directly binding the endoplasmic reticulum-resident receptor STING (stimulator of interferon genes). Group: Pharmaceutical. Alternative Names: Cyclic [G(2',5')pA(3',5')p]; 2'-Guanylic acid, adenylyl-(3'→5')-, cyclic nucleotide; 2',3'-Cyclic guanosine adenosine monophosphate; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate; 2'-3'-cyclic GMP-AMP; cGAMP(2'→5'); c[G(2',5')pA(3',5')p]; Cyclic Gp(2'→5')Ap(3'→5'). CAS No. 1441190-66-4. Pack Sizes: 1 mg. Product ID: B1370-006099. Molecular formula: C20H24N10O13P2. Mole weight: 674.41. Custom synthesis is available. Send your inquiries for more information. | London |
| 2'3'-cGAMP photo affinity probe | 2'3'-cyclic GMP-AMP (2'3'-cGAMP), generated by cyclic GMP-AMP synthase (cGAS) under activation by cytosolic DNA, has a vital role in innate immune response via its receptor protein stimulator of interferon genes (STING) to fight viral infections and tumors. 2'3'-cGAMP-based photoaffinity probes can capture and isolate 2'3'-cGAMP-binding proteins. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: B1370-099265. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Aminoadenosine-5'-Triphosphate 100mM Sodium Solution | 2-Aminoadenosine-5'-Triphosphate, a versatile compound, finds extensive applications in enzymology and biotechnology as a substrate for kinases, ATPases, and nucleotide pyrophosphatases. Additionally, it is noteworthy for its ability to stimulate bone resorption activity in separated osteoclasts, therefore facilitating the study of bone metabolism and related diseases like osteoporosis and osteopenia. Group: Pharmaceutical. Alternative Names: 2-Amino-adenosine-5'-triphosphate; 2-NH2-ATP; 2-Amino-ATP; 2,6-Diaminopurine-ribose-5'-Triphosphate; DAP-rTP; 2-Aminoadenosine 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-triphosphate; 2,6-Diaminopurine ribonucleoside triphosphate; 2,6-Diaminopurine riboside 5'-triphosphate; 2,6-Diaminopurine riboside triphosphate; 2,6-Diaminopurineribosyl-5'-triphosphate. CAS No. 18549-34-3. Pack Sizes: 1 mL. Product ID: B1370-362752. Molecular formula: C10H17N6O13P3. Mole weight: 522.2. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Amino-1,3-dimethyluracil | 6-Amino-1,3-dimethyluracil is one of Caffeine derivatives. Caffeine is a CNS stimulant. Alkaloid, purified from plants of Coffea genus, Rubiaceae. Uses: 6-amino-1,3-dimethyluracil is used as a reagent in the synthesis of new pyrimidine and caffeine derivatives that display highly potential antitumor activity. it is also used as a starting material in the synthesis of fused pyrido-pyrimidines. Group: Pharmaceutical. Alternative Names: 6-Amino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione; 1,3-Dimethyl-4-aminouracil; 1,3-Dimethyl-6-aminouracil; 4-Amino-1,3-dimethyl-2,6-pyrimidinedione; 4-Amino-1,3-dimethyluracil; NSC 15492; 6-Amino-1,3-Dimethyl-1,2,3,4-Tetrahydropyrimidine-2,4-Dione. CAS No. 6642-31-5. Pack Sizes: 1mg;1g;10g. Product ID: NP3466. Molecular formula: C6H9N3O2. Mole weight: 155.15. Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Gingerol | 6-gingerol is the active constituent of fresh ginger. It is bioactive compound found in ginger (Zingiber officinale) with antioxidant activity, which functions as an anti-inflammatory and antitumor agent. It has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin. lt may reduce nausea caused by motion sickness or pregnancy and may also relieve migraine. lt has been investigated for its effect on cancerous tumors in the bowel, breast tissue, ovaries, the pancreas, among other tissues, with positive results. Uses: Anti-inflammatory, antitumor and antioxidant activity. Group: Pharmaceutical. Alternative Names: (S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone;(5S)-5-Hydroxy-1-(4-hydroxy-3-methoxy-phenyl)decan-3-one;3-Decanone, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-. CAS No. 23513-14-6. Pack Sizes: 25 mg. Product ID: NP5162. Molecular formula: C17H26O4. Mole weight: 294.39. Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Chlorotheophylline-[d6] | 8-Chlorotheophylline-[d6] is the labelled analogue of 8-Chlorotheophylline, which is a stimulant drug and a metabolite of Dyphylline. It can be used as a binding agent to form stable salts of pharmaceutical drugs. Group: Pharmaceutical. Alternative Names: 8-Chlorotheophylline-d6; 8-chloro-3,9-dihydro-1,3-(dimethyl-d6)-1H-Purine-2,6-dione; 1,3-(Dimethyl-d6)-8-chloroxanthine; 8-Chloro-1,3-(dimethyl-d6)xanthine; NSC 6113-d6. CAS No. 1346598-95-5. Pack Sizes: 5 mg. Product ID: BLP-011756. Molecular formula: C7HD6ClN4O2. Mole weight: 220.65. Custom synthesis is available. Send your inquiries for more information. | London |
| A-317491 | A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Uses: P2x3 and p2x2/3 receptor antagonist. Group: Pharmaceutical. Alternative Names: ABT 202; A-317491 sodium; ABT202; A317491 sodium; ABT-202; A 317491 sodium; 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid. CAS No. 475205-49-3. Pack Sizes: 1mg;1g;10g. Product ID: 475205-49-3. Molecular formula: C33H27NO8. Mole weight: 565.57. Custom synthesis is available. Send your inquiries for more information. | London |
| A 350619 | A 350619 is an activator of soluble guanylyl cyclase (sGC) that stimulates basal sGC and synergistically activates sGC in the presence of NO. It is effective for the use of ED treatment. Group: Pharmaceutical. Alternative Names: A-350619; A350619; 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide. CAS No. 538368-27-3. Pack Sizes: 1mg;1g;10g. Product ID: 538368-27-3. Molecular formula: C21H25ClN2OS. Mole weight: 389. Custom synthesis is available. Send your inquiries for more information. | London |
| A 350619 hydrochloride | A 350619 hydrochloride is an activator of soluble guanylyl cyclase (sGC) that stimulates basal sGC and synergistically activates sGC in the presence of NO. It is effective for the use of ED treatment. Uses: The treatment of ed. Group: Pharmaceutical. Alternative Names: A-350619 hydrochloride; A350619 hydrochloride; A 350619 hydrochloride; 3-[2-[(4-Chlorophenyl)thiophenyl]-N-[4-(dimethylamino)butyl]-2-propenamide hydrochloride. CAS No. 1217201-17-6. Pack Sizes: 1mg;1g;10g. Product ID: 1217201-17-6. Molecular formula: C21H25ClN2OS.HCl. Mole weight: 425.41. Custom synthesis is available. Send your inquiries for more information. | London |
| A[5']P5[5']A SODIUM SALT | A[5']P5[5']A SODIUM SALT is a paramount biomedical product, standing as a distinguished tool for selective autoimmune conditions and inflammatory dysfunctions. It exhibits its might as a formidable cGAS-STING pathway stimulator. Group: Pharmaceutical. Alternative Names: Adenosine 5'-(hexahydrogen pentaphosphate), 5'.5'-ester with adenosine, pentasodium salt; P1,P5-Di(adenosine-5') pentaphosphate pentasodium salt; Diadenosine pentaphosphate pentasodium salt. CAS No. 4097-4-5. Pack Sizes: 1mg;1g;10g. Product ID: 802535. Molecular formula: C20H24N10Na5O22P5. Mole weight: 1026.28. Custom synthesis is available. Send your inquiries for more information. | London |
| A-740003 | A-740003 is potent, selective and competitive P2X7 receptor antagonist. Its IC50 values are 18 and 40 nM for rat and human receptors respectively measured by agonist-stimulated changes in intracellular calcium concentrations. It displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. It reduces nociception in animal models of persistent neuropathic and inflammatory pain. It showed weak or no activity (IC(50) > 10 muM) at other P2 receptors and an array of other neurotransmitter and peptide receptors, ion channels, reuptake sites, and enzymes. It potently blocked agonist-evoked IL-1beta release (IC(50) = 156 nM) and pore formation (IC(50) = 92 nM) in differentiated human THP-1 cells. It produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Uses: A-740003 produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Group: Pharmaceutical. Alternative Names: A-740003; A 740003; A740003; N-[1-[[(Cyanoamino)(5-quinolinylimino)methyl]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide;N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide. CAS No. 861393-28-4. Pack Sizes: 1mg;1g;10g. Product ID: 861393-28-4. Molecular formula: C26H30N6O3. Mole weight: 474.55. Custom synthesis is available. Send your inquiries for more information. | London |
| AAQ chloride | AAQ chloride is a photoswitchable Kv channel blocker (IC50 = 2 and 64 μM at 500 nm and 380 nm, respectively) that switches conformation from cis to trans at 500 nm and trans to cis at 380 nm. AAQ chloride also stimulates action potential firing of hippocampal neurons in vitro at 500 nm and restores visual responsiveness in blind mice at 380 nm. Group: Pharmaceutical. Alternative Names: N,N,N-Triethyl-2-oxo-2-[[4-[2-[4-[(1-oxo-2-propen-1-yl)amino]phenyl]diazenyl]phenylamino]ethanaminium chloride. Pack Sizes: 1mg;1g;10g. Molecular formula: C23H30ClN5O2. Mole weight: 443.97. Custom synthesis is available. Send your inquiries for more information. | London |
| Abatacept | Abatacept is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). It is a selective T-cell co-stimulation modulator and a protein drug for the autoimmune diseases. Group: Pharmaceutical. Alternative Names: CTLA4lg. CAS No. 332348-12-6. Pack Sizes: 1mg;1g;10g. Product ID: 332348-12-6. Custom synthesis is available. Send your inquiries for more information. | London |
| AC 253 | AC 253 is an amylin (AMY3) receptor antagonist. It inhibits andrenomedulin-stimulated cAMP production in vitro. Group: Pharmaceutical. Alternative Names: L-Tyrosinamide, N-acetyl-L-leucylglycyl-L-arginyl-L-leucyl-L-seryl-L-glutaminyl-L-a-glutamyl-L-leucyl-L-histidyl-L-arginyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginyl-L-threonylglycyl-L-seryl-L-asparaginyl-L-threonyl-. CAS No. 151804-79-4. Pack Sizes: 1mg;1g;10g. Product ID: 151804-79-4. Molecular formula: C122H196N40O39. Mole weight: 2847.11. Custom synthesis is available. Send your inquiries for more information. | London |
| AC 264613 | AC 264613 is a potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 7.5). AC 264613 inhibits interferon regulatory factor 5 and decreases interleukin-12p40 production via lipopolysaccharide-stimulated macrophages. PI hydrolysis, Ca2+ mobilization and cellular proliferation are activated by AC 264613 in vitro (pEC50 = 6.9, 7.0 and 7.5, respectively). Group: Pharmaceutical. Alternative Names: AC-264613; AC 264613; AC264613; (±)-(3R,4S)-2-Oxo-4-phenyl-3-pyrollidinecarboxylic acid 2-[1-(3-bromophenyl)ethylidene]hydrazide. CAS No. 1051487-82-1. Pack Sizes: 1mg;1g;10g. Product ID: 1051487-82-1. Molecular formula: C19H18BrN3O2. Mole weight: 400.27. Custom synthesis is available. Send your inquiries for more information. | London |
| AC 265347 | AC 265347 is a CaSR biased allosteric modulator (pEC50 = 7.8-8.1) that bias signaling towards the accumulation of PERK1/2 and IP1. AC 265347 stimulates CaSR signaling in cellular proliferation and phosphatidyl inositol (PI) hydrolysis assays. It significantly activates human GABAB or type I PTH receptors. Group: Pharmaceutical. Alternative Names: AC 265347; AC-265347; AC265347; α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol; 1-(1,3-benzothiazol-2-yl)-1-(2,4-dimethylphenyl)ethanol. CAS No. 1253901-26-6. Pack Sizes: 1mg;1g;10g. Product ID: 1253901-26-6. Molecular formula: C17H17NOS. Mole weight: 283.39. Custom synthesis is available. Send your inquiries for more information. | London |
| AC-55541 | AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist which displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. It activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. It was well absorbed when administered intraperitoneally to rats, reaching micromolar peak plasma concentrations. It was stable to metabolism by liver microsomes and maintained sustained exposure in rats. Uses: Ac-55541 stimulates cell proliferation, phosphatidylinositol hydrolysis, and calcium mobilization. Group: Pharmaceutical. Alternative Names: AC-55541; AC 55541; AC55541. (2E)-2-[1-(3-Bromophenyl)ethylidene]α-(benzoylamino)-3,4-dihydro-4-oxo-1-phthalazineaceticacidhydrazide;AC 55541;alpha-(Benzoylamino)-3,4-dihydro-4-oxo-1-phthalazineacetic acid (2E)-2-[1-(3-bromophenyl)ethylidene]hydrazide;N-[2-[(2E)-2-[1-(3-bromophenyl)ethylidene]hydrazinyl]-2-oxo-1-(4-oxo-3H-phthalazin-1-yl)ethyl]benzamide. CAS No. 916170-19-9. Pack Sizes: 300 mg. Product ID: B0084-271988. Molecular formula: C25H20BrN5O3. Mole weight: 518.36. Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Hexapeptide-38 | Acetyl hexapeptide 38, also known as breast enhancement peptide, is a peroxisome proliferator-activated receptor-γ coactivator 1α antagonist for cellulite therapy. Acetyl Hexapeptide-38 stimulates peroxisome proliferator-activated receptor Gamma coactivator 1a(PGC-1a) expression and increases fatty tissue volume in specific areas. Group: Pharmaceutical. Alternative Names: Adifyline; Acetyl Hexapeptide 38; Acetyl six peptide; PAW-β. CAS No. 1400634-44-7. Pack Sizes: 1 g. Product ID: BAT-010077. Molecular formula: C30H55N9O10. Mole weight: 701.81. Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl tetrapeptide-2 Acetate | Acetyl Tetrapeptide-2 is a four amino acid peptide that can stimulate the skin's immune defenses and help skin regeneration. It can promote FBLN5 and LOXL1 synthesis and enhance their activity, improve skin firmness. Group: Pharmaceutical. Alternative Names: N-acetyl-L-lysyl-L-alpha-aspartyl-L-valyl-L-tyrosine acetic acid. CAS No. 2763584-38-7. Pack Sizes: 1 g. Product ID: BAT-016164. Molecular formula: C28H43N5O11. Mole weight: 625.67. Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl tetrapeptide-9 acetate | Acetyl tetrapeptide-9 acetate can promote skin remodeling and help achieve firm and plump skin effects. It plays a role in the stimulation of basement membrane polysaccharide (lumican) and the synthesis of collagen I. Group: Pharmaceutical. Alternative Names: Ac-Gln-Asp-Val-His-OH.CH3CO2H; Ac-QDVH.CH3CO2H; N-acetyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidine acetic acid. CAS No. 2763583-72-6. Pack Sizes: 1 g. Product ID: BAT-016217. Molecular formula: C24H37N7O11. Mole weight: 599.59. Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-RYYRIK-NH2 TFA | Ac-RYYRIK-NH2 TFA is a potent and partial agonist on ORL1 transfected in CHO cells (Kd = 1.5 nM). Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in membranes and sections of rat brain. Group: Pharmaceutical. Pack Sizes: 100 mg. Product ID: B1370-382766. Molecular formula: C46H71F3N14O11. Mole weight: 1053.13. Custom synthesis is available. Send your inquiries for more information. | London |
| Alfacalcidol | A synthetic analog of Calcitiol (the hormonal form of vitamin D3), which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source. Group: Pharmaceutical. Alternative Names: 1-Hydroxycholecalciferol; Alfarol; EinsAlpha; Alpha-Calcidol; One-Alpha; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol. CAS No. 41294-56-8. Pack Sizes: 50 mg. Product ID: B0084-068405. Molecular formula: C27H44O2. Mole weight: 400.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Almitrine | Almitrine, also called as Duxil, a diphenylmethylpiperazine derivative, is a respiratory stimulant by the ATC that improves ventilation/perfusion relationships. Group: Pharmaceutical. Alternative Names: ALMITRINE;1-[2,4-Bis(allylamino)-1,3,5-triazin-6-yl]-4-[bis(4-fluorophenyl)methyl]piperazine;2,4-Bis(allylamino)-6-[4-[bis(p-fluorophenyl)methyl]-1-piperazinyl]-s-triazine;6-[4-[Bis(4-fluorophenyl)methyl]-1-piperazinyl]-N,N'-di(2-propenyl)-1,3,5-triazine. CAS No. 27469-53-0. Pack Sizes: 1mg;1g;10g. Product ID: 27469-53-0. Molecular formula: C26H29F2N7. Mole weight: 477.56. Custom synthesis is available. Send your inquiries for more information. | London |
| α-epidermal growth factor, human | Recombinant human epidermal growth factor has the same structure as the human epidermal growth factor. EGF binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. Recombinant human epidermal growth factor is approved for the treatment of diabetic foot ulcers. Uses: The treatment of diabetic foot ulcers. Group: Pharmaceutical. Alternative Names: Human EGF; Nepidermin. CAS No. 62253-63-8. Pack Sizes: 1 mg. Product ID: BAT-010173. Molecular formula: C270H401N73O83S7. Mole weight: 6222. Custom synthesis is available. Send your inquiries for more information. | London |
| α-Viniferin | α-Viniferin isolated from the herb of Carex humilis Leyss. It inhibits AChE activity is specific, reversible and noncompetitive,down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages. Uses: Anti-inflammatory activity; antifungal; inhibits protein kinase c; inhibits prostaglandin h2 synthase carex humilis. Group: Pharmaceutical. Alternative Names: (+)-α-viniferin. CAS No. 62218-13-7. Pack Sizes: 1 mg. Product ID: NP4646. Molecular formula: C42H30O9. Mole weight: 678.7. Custom synthesis is available. Send your inquiries for more information. | London |
| Amrinone | Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Group: Pharmaceutical. Alternative Names: Inamrinone;Wincoram;Inocor;Cordemcura;Win-40680;Win40680;3-Amino-5-pyridin-4-yl-1H-pyridin-2-one. CAS No. 60719-84-8. Pack Sizes: 2.5 g. Product ID: B0084-072903. Molecular formula: C10H9N3O. Mole weight: 187.2. Custom synthesis is available. Send your inquiries for more information. | London |
| Amylin (human) | Amylin, islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone secreted by pancreatic β-cells. It inhibits insulin-stimulated glucose uptake, delays gastric emptying and promotes satiety. It has glucose lowering effects in vivo. It is also used to study the mechanisms of amyloid deposition and its role in molecular misfolding processes expecially in conditions such as diabetes type II. Group: Pharmaceutical. Alternative Names: L-Tyrosinamide, L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-, cycl. CAS No. 122384-88-7. Pack Sizes: 1 mg. Product ID: BAT-006084. Molecular formula: C165H261N51O55S2. Mole weight: 3903.33. Custom synthesis is available. Send your inquiries for more information. | London |
| (±)-Anatabine | (±)-Anatabine is a metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Group: Pharmaceutical. Alternative Names: 2,3'-Bipyridine, 1,2,3,6-tetrahydro-; (+/-)-1,2,3,6-Tetrahydro-2,3'-bipyridine; (+/-)-Anatabine; 1,2,3,6-Tetrahydro-2,3'-bipyridine; 2,3'-Bipyridine, 1,2,3,6-tetrahydro-, (±)-; (RS)-Anatabine; (±)-1,2,3,6-Tetrahydro-2,3'-bipyridine; 1,2,3,6-Tetrahydro-2,3'-dipyridine. CAS No. 2743-90-0. Pack Sizes: 250 mg. Product ID: B1410-177777. Molecular formula: C10H12N2. Mole weight: 160.22. Custom synthesis is available. Send your inquiries for more information. | London |
| Antagonist G | Antagonist G is a substance P analog, which is a broad spectrum neuropeptide growth factor antagonist and antiproliferative agent. It was developed for the treatment of small cell lung cancer. It could inhibit neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro. It also inhibits growth of SCLC xenografts in mice in vivo. It blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. It activates JNK and stimulates apoptosis. It is an anticancer agent and is resistant to degradation by peptidases. Group: Pharmaceutical. Alternative Names: [Arg6,D-Trp7,9,N-MePhe8]-Substance P(6-11). CAS No. 115150-59-9. Pack Sizes: 1 mg. Product ID: BAT-006104. Molecular formula: C49H66N12O6S. Mole weight: 951.2. Custom synthesis is available. Send your inquiries for more information. | London |
| Apatinib mesylate | Apatinib mesylate is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: YN968D1. CAS No. 1218779-75-9. Pack Sizes: 250 mg. Product ID: B2693-457664. Molecular formula: C25H27N5O4S. Mole weight: 493.58. Custom synthesis is available. Send your inquiries for more information. | London |
| Arborinine | Arborinine is an alkaloid isolated from Erthela bahiensis. Arborinine was shown to inhibit splenocytes proliferation under ConA or PWM stimulation and promote apoptosis on splenocytes and thymocytes stimulated with PWM in 24h. It also decreases production of Interleukin-10 by splenocytes and thymocytes stimulated with ConA or PWM. Group: Pharmaceutical. Alternative Names: 1-hydroxy-2,3-dimethoxy-10-methylacridin-9-one. CAS No. 5489-57-6. Pack Sizes: 1 mg. Product ID: NP0701. Molecular formula: C16H15NO4. Mole weight: 285.299. Custom synthesis is available. Send your inquiries for more information. | London |
| Aromadendrin | Aromadendrin, which usually comes from the bark of Eucalyptus calophylla, exhibits anti-inflammatory activity through the suppression of nuclear translocation of NF-κB and phosphorylation of JNK in LPS-stimulated RAW 264.7 macrophage cells. Aromadendrin may represent a potential therapeutic candidate for the management of type 2 DM. Uses: Anti-inflammatory/antioxidant/anti-diabetic. Group: Pharmaceutical. Alternative Names: 3,5,7,4'-Tetrahydroxyflavanone; Dihydrokaempferol; aromadedrin; (2R)-2,3-Dihydro-3β,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (2R,3R)-2,3-Dihydro-2-(4-hydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one; Katuranin. CAS No. 480-20-6. Pack Sizes: 50 mg. Product ID: NP1939. Molecular formula: C15H12O6. Mole weight: 288.3. Custom synthesis is available. Send your inquiries for more information. | London |
| Astragaloside II | Astragaloside II is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Astragaloside II has cardioprotective effects as well as causing improvement in cognitive function. It is used in the prevention of cardio-cerebral vascular diseases. It stimulates osteoblast differentiation resulting in bone formation. It exhibits a significant induction of proliferation, differentiation and mineralization in primary osteoblasts. It is a potent MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Uses: Astragaloside ii has cardioprotective effects as well as causing improvement in cognitive function. it is used in the prevention of cardio-cerebral vascular diseases. it may be used as a potential adjunctive agent for hepatic cancer chemotherapy. Group: Pharmaceutical. Alternative Names: (3b,6a,16b, 20R,24S)-3-[(2-O-Acetyl-b-D-xylopyranosyl)oxy]-20,24-Epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl b-D-glucopyranoside; Astrasieversianin VIII. CAS No. 84676-89-1. Pack Sizes: 20 mg. Product ID: NP7020. Molecular formula: C43H70O15. Mole weight: 827.01. Custom synthesis is available. Send your inquiries for more information. | London |
| Atpenin A5 | Atpenin A5 is an inhibitor of SDHB, SDHC and SDHD. It is an antifungal antibiotic produced by Penicillium sp. and an ubiquinone-binding site inhibitor of succinate dehydrogenase with IC50s of 12 nM for nematode and IC50s of 3.7 nM for mammalian mitochondria. Atpenin A5 is the most effective inhibitor against complex II from all the atpenins and has been shown to protect against cardiac-reperfusion injury in rat studies through the stimulation of mitochondrial KATP channels. Group: Pharmaceutical. Alternative Names: Antibiotic FO-125A5. CAS No. 119509-24-9. Pack Sizes: 50 mg. Product ID: BBF-04652. Molecular formula: C15H21Cl2NO5. Mole weight: 366.2. Custom synthesis is available. Send your inquiries for more information. | London |
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