Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| α-Melanocyte-Stimulating Hormone (MSH), amide | α-Melanocyte-Stimulating Hormone (MSH), is an endogenous melanocortin receptor agonist that results in the activation of adenylyl cyclase, with anti-inflammatory effect. Group: Pharmaceutical. CAS No. 581-05-5. Pack Sizes: 10 mg. Product ID: BAT-006107. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 4,4'-DIHYDROXY-2-METHOXYCHALCONE | Echinatin is extracted from the root of Glycyrrhiza glabra L. It inhibits DNP-ATPase activity while stimulating range latent ATPase activity in the low concentration. It disturbs the mitochondrial energy transfer reactions and membrane permeability. It was demonstrated to inhibit the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. Group: Pharmaceutical. CAS No. 34221-41-5. Pack Sizes: 10 mg. Product ID: NP0936. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Group: Pharmaceutical. CAS No. 183552-38-7. Pack Sizes: 10 mg. Product ID: BAT-006166. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Hexapeptide-1 | Acetyl Hexapeptide-1, also known as Melitane, is a biomimetic peptide antagonist of the α-MSH (α-Melanocyte-Stimulating Hormone). It stimulates tyrosinase activity, melanin synthesis and melanocyte dendricity, and protects DNA damage caused by UV exposure. Group: Pharmaceutical. CAS No. 448944-47-6. Pack Sizes: 5 mg. Product ID: BAT-006234. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Alarelin acetate | Alarelin acetate is a synthetic Gonadotrophin-releasing hormone agonist. It is the acetate form of a hypothalamic peptide. It is a potent LH-RH agonist in rats and mice. It reversibly delays sexual maturation in rats, stimulates spawning activity in fish. It could inducte ovulation and is used to treat endmometriosis. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Uses: Alarelin acetate could inducte ovulation and is used to treat endmometriosis. it is responsible for the secretion of gonadotropins, luteinizing hormone (lh) and follicle-stimulating hormone (fsh), from the pituitary glands. Group: Pharmaceutical. CAS No. 79561-22-1. Pack Sizes: 100 mg. Product ID: BAT-010030. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Almitrine dimesylate | Almitrine dimesylate is the dimethanesulfonate salt of almitrine. It acts as an agonist of peripheral chemoreceptors located on the carotid bodies, thereby stimulating respiratory system. Group: Pharmaceutical. CAS No. 29608-49-9. Pack Sizes: 20 g. Product ID: B0084-089581. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Anamorelin Fumarate | Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. Group: Pharmaceutical. CAS No. 339539-92-3. Pack Sizes: 50 mg. Product ID: B0084-463631. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Anamorelin HCl | Anamorelin, also known as RC-1291 or ONO-7643, is the orally bioavailable, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Uses: For research used only. Group: Pharmaceutical. CAS No. 861998-00-7. Pack Sizes: 100 mg. Product ID: B0084-462661. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bemcentinib | Bemcentinib is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer. The receptor tyrosine kinase Axl may play an important role in cancer progression, invasion, metastasis, drug resistance, and patient mortality. R428 inhibits Axl with low nanomolar activity and blocked Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Pharmacologic investigations revealed favorable exposure after oral administration such that R428-treated tumors displayed a dose-dependent reduction in expression of the cytokine granulocyte macrophage colony-stimulating factor and the epithelial-mesenchymal transition transcriptional regulator Snail. In support of an earlier study, R428 inhibited angiogenesis in corneal micropocket and tumor models. R428 administration reduced metastatic burden and extended survival in MDA-MB-231 intracardiac and 4T1 orthotopic (median survival, >80 days compared with 52 days; P < 0.05) mouse models of breast cancer metastasis. Additionally, R428 synergized with cisplatin to enhance suppression of liver micrometastasis. Our results show that Axl signaling regulates breast cancer metastasis at multiple levels in tumor cells and tumor stromal cells and that selective Axl blockade confers therapeutic value in prolonging survival of animals bearing metast | London |
| Bremelanotide | Bremelanotide is a peptide melanocortin receptor agonist developed for the treatment of sexual dysfunction, hemorrhagic shock and reperfusion injury. Uses: bremelanotide is a synthetic peptide drug that has generated a lot of interest in the drug development community due to its potential applications in sexual dysfunction and other conditions. this peptide is a synthetic analog of the natural hormone alpha-msh (melanocyte stimulating hormone) and acts as a non-selective agonist of the melanocortin receptors mc3-r and mc4-r. one of the main areas. Group: Pharmaceutical. CAS No. 189691-06-3. Pack Sizes: 10 mg. Product ID: BAT-010024. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chitosan | Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 9012-76-4. Pack Sizes: 1kg. Product ID: B1370-187887. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Degarelix acetate hydrate | Degarelix acetate is a synthetic peptide that acts as a gonadotrophin-releasing hormone (GnRH) antagonist. Degarelix targets GnRH receptors in the pituitary gland, resulting in reduction of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and suppression of testosterone. Group: Pharmaceutical. CAS No. 934246-14-7. Pack Sizes: 100 mg. Product ID: BAT-010777. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glimepiride | Glimepiride is a medium to long-acting sulfonylurea antidiabetic drug. It acts by stimulating the insulin release from pancreatic β-cells and decreases glucose output from the liver. Group: Pharmaceutical. CAS No. 93479-97-1. Pack Sizes: 10 g. Product ID: NP3448. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Golotimod | Golotimod is an orally bioactive synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and antineoplastic activities. Golotimod has been shown to inhibit the expression of STAT-3, reversing immunosuppression and stimulating an anti-tumor immune response. It may stimulate the production of T-lymphocytes (in particular the helper T [Th1] cells), activate macrophages, and increase levels of interleukin 2 and interferon gamma. Group: Pharmaceutical. CAS No. 229305-39-9. Pack Sizes: 50 mg. Product ID: BAT-010153. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hesperetin | Hesperetin, a flavonoid widely found in citrus, is also one of the vitamin Ps that the human body is generally prone to lack. Study showed that it promoted osteogenic differentiation of human mesenchymal stem cells in vitro. Hesperetin can be used in health products. Hesperetin has an antioxidant effect, reduces the production of free radicals, plays an anti-aging role and removes wrinkles. It can also enhance the homeostasis of epidermal osmotic barrier by stimulating epidermal proliferation and differentiation, so as to repair the skin barrier. In addition, hesperetin has whitening and lightening spots, brightening skin, removing dark circles, anti-inflammatory and antibacterial, hair care and many other effects. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 520-33-2. Pack Sizes: 50 g. Product ID: NP1882. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hesperidin | Hesperidin is a flavonoid substance widely present in the peel of Citrus sinensis, and is also one of the vitamin P that the human body is generally easy to lack. Hesperidin has an antioxidant effect, reduces the generation of free radicals, and plays a role in anti-aging and wrinkling. It can also enhance the homeostasis of the epidermal osmotic barrier by stimulating epidermal proliferation and differentiation, to repair the skin barrier. In addition, hesperidin also has whitening and lightening spots, brightening skin, removing dark circles, anti-inflammatory and antibacterial, hair care, and many other effects. Uses: Anti-inflammatory; analgesic; antioxidant; anticarcinogenic effect. Group: Pharmaceutical. CAS No. 520-26-3. Pack Sizes: 2 kg. Product ID: NP2550. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Levosimendan Impurities | Levosimendan Impurities are integral entities within the biomedical paradigm, pivotal for meticulous purity analysis of Levosimendan, a cornerstone heart failure therapeutic. Grasping these impurities underpins the enhancement of drug safety and efficacy, thus catalyzing advancements in cardiovascular treatment research and stimulating progressive pharmaceutical innovations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Melanostatin DM | Melanostatin DM is an inhibitor of α-melanocyte stimulating hormone (α-MSH). It is used in cosmetics as a whitening agent. Group: Pharmaceutical. CAS No. 123689-72-5. Pack Sizes: 5 mg. Product ID: BAT-006230. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Melanotan I | A synthetic analogue of α-melanocyte stimulating hormone (α-MSH). Group: Pharmaceutical. CAS No. 75921-69-6. Pack Sizes: 10 mg. Product ID: BAT-010533. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Mianserin Hydrochloride | Mianserin Hydrochloride is a psychoactive drug of the tetracyclic antidepressant.It is classified as a noradrenergic and specific serotonergic antidepressant (NaSSA) and has antidepressant, anxiolytic (anti-anxiety), hypnotic (sedating), antiemetic (nausea and vomiting-attenuating), orexigenic (appetite-stimulating), and antihistamine effects.It is not approved for use in the US. Uses: Antidepressive agents, second-generation. Group: Pharmaceutical. CAS No. 21535-47-7. Pack Sizes: 10 g. Product ID: B2693-062932. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Oclacitinib | Oclacitinib, also known as PF03394197, is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Oclacitinib inhibited JAK family members by 50% at concentrations (IC50 's) ranging from 10 to 99 nM and did not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000 nm). Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC50 's ranging from 36 to 249 nm. Oclacitinib had minimal effects on cytokines that did not activate the JAK1 enzyme in cells (erythropoietin, granulocyte/macrophage colony-stimulating factor, IL-12, IL-23; IC50 's > 1000 nm). These results demonstrate that oclacitinib is a targeted therapy that selectively inhibits JAK1-dependent cytokines involved in allergy, inflammation, and pruritus and suggests these are the mechanisms by which oclacitinib effectively controls clinical signs associated with allergic skin disease in dogs. Group: Pharmaceutical. CAS No. 1208319-26-9. Pack Sizes: 50 mg. Product ID: B0084-462291. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Palmitoyl Tetrapeptide-3 | Palmitoyl tetrapeptide-3 is a synthetic peptide used for skin care and anti-aging cosmetics. Palmitoyl tetrapeptide 3 corresponds to the 341-344 amino acid sequence of the heavy chain of human immunoglobulin, which has the effect of stimulating phagocytosis. Group: Pharmaceutical. CAS No. 221227-05-0. Pack Sizes: 2 g. Product ID: BAT-010581. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PD-173955 | PD-173955 is a src tyrosine kinase inhibitor. PD173955 inhibited Bcr-Abl-dependent cell growth. PD173955 showed cell cycle arrest in G(1). PD173955 has an IC(50) of 1-2 nM in kinase inhibition assays of Bcr-Abl, and in cellular growth assays it inhibits Bcr-Abl-dependent substrate tyrosine phosphorylation. PD173955 inhibited kit ligand-dependent c-kit autophosphorylation (IC(50) = approximately 25 nM) and kit ligand-dependent proliferation of M07e cells (IC(50) = 40 nM) but had a lesser effect on interleukin 3-dependent (IC(50) = 250 nM) or granulocyte macrophage colony-stimulating factor (IC(50) = 1 microM)-dependent cell growth. Group: Pharmaceutical. CAS No. 260415-63-2. Pack Sizes: 10 mg. Product ID: B0084-088782. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Repaglinide | Repaglinide is a potassium channel blocker, which lowers blood glucose by stimulating the release of insulin from the pancreas, used for the treatment of type II diabetes. Group: Pharmaceutical. CAS No. 135062-02-1. Pack Sizes: 1 g. Product ID: NP3248. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Repaglinide Impurities | Repaglinide Impurities are crucial in the biomedical industry for quality control and the development of antidiabetic medications. These impurities are analyzed to ensure the purity and efficacy of Repaglinide, a drug used to manage type 2 diabetes by stimulating insulin release from the pancreas. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Talabostat mesylate | Talabostat mesylate is the orally bioavailable mesylate salt of an amino boronic dipeptide with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines. Uses: For research used only. Group: Pharmaceutical. CAS No. 150080-09-4. Pack Sizes: 20 mg. Product ID: B0084-084554. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (1'S,2'S)-Nicotine-1'-Oxide-[d3] | A metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Group: Pharmaceutical. Pack Sizes: 10 mg. Product ID: BLP-014878. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2',3'-cGAMP | 2',3'-cGAMP was considered to be the metazoan second messenger which is produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. It can activate innate immunity by directly binding the endoplasmic reticulum-resident receptor STING (stimulator of interferon genes). Group: Pharmaceutical. CAS No. 1441190-66-4. Pack Sizes: 1 mg. Product ID: B1370-006099. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6-Gingerol | 6-gingerol is the active constituent of fresh ginger. It is bioactive compound found in ginger (Zingiber officinale) with antioxidant activity, which functions as an anti-inflammatory and antitumor agent. It has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin. lt may reduce nausea caused by motion sickness or pregnancy and may also relieve migraine. lt has been investigated for its effect on cancerous tumors in the bowel, breast tissue, ovaries, the pancreas, among other tissues, with positive results. Uses: Anti-inflammatory, antitumor and antioxidant activity. Group: Pharmaceutical. CAS No. 23513-14-6. Pack Sizes: 25 mg. Product ID: NP5162. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 8-Chlorotheophylline-[d6] | 8-Chlorotheophylline-[d6] is the labelled analogue of 8-Chlorotheophylline, which is a stimulant drug and a metabolite of Dyphylline. It can be used as a binding agent to form stable salts of pharmaceutical drugs. Group: Pharmaceutical. CAS No. 1346598-95-5. Pack Sizes: 5 mg. Product ID: BLP-011756. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC-55541 | AC-55541 is a novel small-molecule protease-activated receptor 2(PAR2) agonist which displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. It activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 200 to 1000 nM. It was well absorbed when administered intraperitoneally to rats, reaching micromolar peak plasma concentrations. It was stable to metabolism by liver microsomes and maintained sustained exposure in rats. Uses: Ac-55541 stimulates cell proliferation, phosphatidylinositol hydrolysis, and calcium mobilization. Group: Pharmaceutical. CAS No. 916170-19-9. Pack Sizes: 300 mg. Product ID: B0084-271988. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac9-25 | Ac9-25 is a N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting as a formyl peptide receptor 1 (FPR1) ligand. Group: Pharmaceutical. CAS No. 284040-76-2. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016353. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac9-25 acetate | Ac9-25 acetate is an N-terminal peptide of Annexin I (AI/Lipocortin I) that inhibits leukocyte extravasation. It stimulates neutrophil NADPH oxidase activation by acting as a formyl peptide receptor 1 (FPR1) ligand. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016203. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Hexapeptide-38 | Acetyl hexapeptide 38, also known as breast enhancement peptide, is a peroxisome proliferator-activated receptor-γ coactivator 1α antagonist for cellulite therapy. Acetyl Hexapeptide-38 stimulates peroxisome proliferator-activated receptor Gamma coactivator 1a(PGC-1a) expression and increases fatty tissue volume in specific areas. Group: Pharmaceutical. CAS No. 1400634-44-7. Pack Sizes: 1 g. Product ID: BAT-010077. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl hexapeptide 38 Acetate | Acetyl hexapeptide 38 Acetate, breast enhancement peptide, is a kind of acetylated hexapeptide. It can significantly stimulate the use of the site of fat synthesis, and increase the volume of the chest or cheek, shape the perfect body. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016245. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Tetrapeptide-2 | Acetyl Tetrapeptide-2 is a four amino acid peptide that can stimulate the skin's immune defenses and help skin regeneration. It can promote FBLN5 and LOXL1 synthesis and enhance their activity, improve skin firmness. Uses: acetyl tetrapeptide-2 is a synthetic peptide composed of four amino acids: alanine, glutamine, serine, and arginine. it is a small molecule that is easily absorbed by the body, making it an attractive candidate for drug delivery systems. one of the key mechanisms of at-2 is its ability to modulate the expression of key proteins involved in regulating cellular processes associated with aging and. Group: Pharmaceutical. CAS No. 757942-88-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-009988. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl tetrapeptide-2 acetate | Acetyl Tetrapeptide-2 is a four amino acid peptide that can stimulate the skin's immune defenses and help skin regeneration. It is most commonly used as a skin conditioner. Group: Pharmaceutical. CAS No. 2763584-38-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016164. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl tetrapeptide-9 acetate | Acetyl tetrapeptide-9 acetate can promote skin remodeling and help achieve firm and plump skin effects. It plays a role in the stimulation of basement membrane polysaccharide (lumican) and the synthesis of collagen I. Group: Pharmaceutical. CAS No. 2763583-72-6. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016217. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-RYYRIK-NH2 acetate | Ac-RYYRIK-NH2 acetate is a potent and partial agonist on ORL1 transfected in CHO cells (Kd = 1.5 nM). Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in membranes and sections of rat brain. Group: Pharmaceutical. CAS No. 2863659-08-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016380. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Alfacalcidol | A synthetic analog of Calcitiol (the hormonal form of vitamin D3), which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source. Group: Pharmaceutical. CAS No. 41294-56-8. Pack Sizes: 50 mg. Product ID: B0084-068405. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| α-epidermal growth factor, human | Recombinant human epidermal growth factor has the same structure as the human epidermal growth factor. EGF binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. Recombinant human epidermal growth factor is approved for the treatment of diabetic foot ulcers. Uses: The treatment of diabetic foot ulcers. Group: Pharmaceutical. CAS No. 62253-63-8. Pack Sizes: 1 mg. Product ID: BAT-010173. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| α-Viniferin | α-Viniferin isolated from the herb of Carex humilis Leyss. It inhibits AChE activity is specific, reversible and noncompetitive,down-regulating STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages. Uses: Anti-inflammatory activity; antifungal; inhibits protein kinase c; inhibits prostaglandin h2 synthase carex humilis. Group: Pharmaceutical. CAS No. 62218-13-7. Pack Sizes: 1 mg. Product ID: NP4646. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Amrinone | Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Group: Pharmaceutical. CAS No. 60719-84-8. Pack Sizes: 2.5 g. Product ID: B0084-072903. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Amylin (human) | Amylin, islet Amyloid Polypeptide (IAPP), is a 37-residue peptide hormone secreted by pancreatic β-cells. It inhibits insulin-stimulated glucose uptake, delays gastric emptying and promotes satiety. It has glucose lowering effects in vivo. It is also used to study the mechanisms of amyloid deposition and its role in molecular misfolding processes expecially in conditions such as diabetes type II. Group: Pharmaceutical. CAS No. 122384-88-7. Pack Sizes: 1 mg. Product ID: BAT-006084. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (±)-Anatabine | (±)-Anatabine is a metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Group: Pharmaceutical. CAS No. 2743-90-0. Pack Sizes: 250 mg. Product ID: B1410-177777. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Antagonist G | Antagonist G is a substance P analog, which is a broad spectrum neuropeptide growth factor antagonist and antiproliferative agent. It was developed for the treatment of small cell lung cancer. It could inhibit neuropeptide-dependent and -independent proliferation of small cell lung cancer in vitro. It also inhibits growth of SCLC xenografts in mice in vivo. It blocks Swiss 3T3 cell growth induced by vasopressin, gastrin-releasing peptide and bradykinin. It activates JNK and stimulates apoptosis. It is an anticancer agent and is resistant to degradation by peptidases. Group: Pharmaceutical. CAS No. 115150-59-9. Pack Sizes: 1 mg. Product ID: BAT-006104. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Apatinib mesylate | Apatinib mesylate is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 1218779-75-9. Pack Sizes: 250 mg. Product ID: B2693-457664. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Arborinine | Arborinine is an alkaloid isolated from Erthela bahiensis. Arborinine was shown to inhibit splenocytes proliferation under ConA or PWM stimulation and promote apoptosis on splenocytes and thymocytes stimulated with PWM in 24h. It also decreases production of Interleukin-10 by splenocytes and thymocytes stimulated with ConA or PWM. Group: Pharmaceutical. CAS No. 5489-57-6. Pack Sizes: 1 mg. Product ID: NP0701. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Aromadendrin | Aromadendrin, which usually comes from the bark of Eucalyptus calophylla, exhibits anti-inflammatory activity through the suppression of nuclear translocation of NF-κB and phosphorylation of JNK in LPS-stimulated RAW 264.7 macrophage cells. Aromadendrin may represent a potential therapeutic candidate for the management of type 2 DM. Uses: Anti-inflammatory/antioxidant/anti-diabetic. Group: Pharmaceutical. CAS No. 480-20-6. Pack Sizes: 50 mg. Product ID: NP1939. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Astragaloside II | Astragaloside II is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. Astragaloside II has cardioprotective effects as well as causing improvement in cognitive function. It is used in the prevention of cardio-cerebral vascular diseases. It stimulates osteoblast differentiation resulting in bone formation. It exhibits a significant induction of proliferation, differentiation and mineralization in primary osteoblasts. It is a potent MDR reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy. Uses: Astragaloside ii has cardioprotective effects as well as causing improvement in cognitive function. it is used in the prevention of cardio-cerebral vascular diseases. it may be used as a potential adjunctive agent for hepatic cancer chemotherapy. Group: Pharmaceutical. CAS No. 84676-89-1. Pack Sizes: 20 mg. Product ID: NP7020. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Atpenin A5 | Atpenin A5 is an inhibitor of SDHB, SDHC and SDHD. It is an antifungal antibiotic produced by Penicillium sp. and an ubiquinone-binding site inhibitor of succinate dehydrogenase with IC50s of 12 nM for nematode and IC50s of 3.7 nM for mammalian mitochondria. Atpenin A5 is the most effective inhibitor against complex II from all the atpenins and has been shown to protect against cardiac-reperfusion injury in rat studies through the stimulation of mitochondrial KATP channels. Group: Pharmaceutical. CAS No. 119509-24-9. Pack Sizes: 50 mg. Product ID: BBF-04652. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avatrombopag | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Group: Pharmaceutical. CAS No. 570406-98-3. Pack Sizes: 100 mg. Product ID: B2693-144359. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avatrombopag maleate | Avatrombopag, also known as AKR-501, YM477, AS 1670542 or E5501, is a novel orally-active thrombopoietin (TPO) receptor agonist. AKR-501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR-501 is an orally-active TPO receptor agonist that may be useful in the treatment of patients with thrombocytopenia. Group: Pharmaceutical. CAS No. 677007-74-8. Pack Sizes: 100 mg. Product ID: B2693-216033. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Avicularin | Avicularin, a natural plant flavonoid isolated from the herbs of Polygonum aviculare, exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells. By decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase, avicularin can inhibit the accumulation of the intracellular lipids. Uses: Anti-inflammatory. Group: Pharmaceutical. CAS No. 572-30-5. Pack Sizes: 10 mg. Product ID: NP1949. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AY-NH2 | AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Group: Pharmaceutical. CAS No. 352017-71-1. Pack Sizes: 5 mg. Product ID: BAT-006106. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azoramide | Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It is a dual-function endoplasmic reticulum (ER) modulator in vitro. It improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones to protect cells against ER stress in multiple systems. It regulates ER folding and secretion capacity without inducing ER stress. It might have the protective effects of enhancing chaperone expression and reducing protein synthesis without inducing cytotoxicity and apoptosis. It showed potent antidiabetic activity in two independent mouse models of obesity by protecting pancreatic β cell function against ER stress and improving insulin sensitivity in vivo. It improves glucose homeostasis in mice with genetic obesity and diet-induced obesity. Group: Pharmaceutical. CAS No. 932986-18-0. Pack Sizes: 100 mg. Product ID: B1370-474920. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Batefenterol | Batefenterol is a Beta 2 adrenergic receptor agonist and also a Muscarinic receptor antagonist. It shows high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic receptors (Ki = 1.3 nM) and hβ2-adrenoceptors (Ki = 3.7 nM). Batefenterol is a hβ2-adrenoceptor agonist with EC50 value of 0.29 nM for stimulation of cAMP levels. This is 440- and 320-fold functional selectivity over hβ1- and hβ3-adrenoceptors. In Jul 2016, GlaxoSmithKline completed a phase II trial for Chronic obstructive pulmonary disease in USA, Germany and South Africa. Uses: Chronic obstructive pulmonary disease. Group: Pharmaceutical. CAS No. 743461-65-6. Pack Sizes: 25 mg. Product ID: B0084-476591. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Batefenterol Succinate | Batefenterol is a beta 2 adrenergic receptor agonist and also a muscarinic receptor antagonist. It shows high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic receptors (Ki = 1.3 nM) and hβ2-adrenoceptors (Ki = 3.7 nM). Batefenterol is a hβ2-adrenoceptor agonist with EC50 value of 0.29 nM for stimulation of cAMP levels. This is 440- and 320-fold functional selectivity over hβ1- and hβ3-adrenoceptors. Group: Pharmaceutical. CAS No. 945905-37-3. Pack Sizes: 25 mg. Product ID: B2693-383251. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Benzyl nicotinate | Benzyl nicotinate is a metabolite of Nicotine, which is a potent parasympathomimetic stimulant. Group: Pharmaceutical. CAS No. 94-44-0. Pack Sizes: 1 kg. Product ID: NP2761. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Berberrubine | Berberrubine comes from the herbs of Coptis chinensis Franch. Berberrubine dose-dependently inhibited IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha. Uses: Antitumor/anti-diabetic. Group: Pharmaceutical. CAS No. 15401-69-1. Pack Sizes: 20 mg. Product ID: NP0537. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Beta-Methylphenethylamine Impurities | Beta-Methylphenethylamine Impurities are crucial in the biomedical industry for analyzing drug purity and efficacy, particularly in pharmaceuticals related to neurodegenerative disorders and stimulant-related treatments. These impurities help in the refinement and standardization of medications, ensuring their safety and therapeutic potential in clinical applications. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Biotinoyl tripeptide-1 | Biotinoyl tripeptide-1 is a peptide beneficial for hair conditioning. Biotinoyl tripeptide-1 is also used in anti-aging cosmetics. Biotinoyl tripeptide-1 is a tripeptide that combines vitamin H with the Matrikine series GHK. Biotinoyl tripeptide-1 can stimulate the synthesis of collagen IV and laminin 5, and fix hair in the dermal hair follicle to prevent hair loss. Uses: biotinylated tripeptide-1, also known as vitamin h peptide, plays a vital role in drug discovery due to its unique properties and potential therapeutic applications. this peptide is composed of biotin, a water-soluble b vitamin that is essential for various biochemical processes, and a tripeptide composed of three amino acids. in drug discovery, biotinylated tripeptide-1 has received attention. Group: Pharmaceutical. CAS No. 299157-54-3. Pack Sizes: 1 g. Product ID: BAT-010782. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| C16 Ceramide | C16 ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling. It has also been found to activate NF-κB and PKCζ3. Uses: A predominant, rather hydrophobic natural ceramide. activates a cytosolic serine/threonine protein phosphatase in t9 cells; induces egf receptor phosphorylation in a-431 cells; stimulates ceramide-activated protein kinase. Group: Pharmaceutical. CAS No. 24696-26-2. Pack Sizes: 100 mg. Product ID: B1370-059982. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Caprooyl Tetrapeptide-3 acetate | Caprooyl tetrapeptide-3 is a synthetic or plant-derived peptide that stimulates the production of collagen, elastin, and hyaluronic acid. Caprooyl tetrapeptide-3 is used for skin repair. Group: Pharmaceutical. CAS No. 1012317-71-3. Pack Sizes: 1 g. Product ID: B0001-112367. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cediranib maleate | Cediranib maleate is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM. It also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM. It inhibits VEGF-stimulated proliferation with IC50 of 0.4 nM in vitro. It suppresses PDGF-AA with IC50 of 0.04 μM in MG63 cell lines. It even suppresses tubule sprouting at subnanomolar concentrations and inhibits VEGF-induced angiogenesis in vivo. It causes hypertrophy in bone growth plate and prevents luteal development in ovary. It shows broad spectrum activity in human tumor models at doses that are well tolerated. It causes regression of vascular tissues in human lung tumor xenografts. Group: Pharmaceutical. CAS No. 857036-77-2. Pack Sizes: 100 mg. Product ID: B2693-459903. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cepharanthine | Cepharanthine (CEP) is a biscoclaurine alkaloid isolated from Stephania cepharantha. It has anticancer, antiinflammatory, antiallergic, immunomo- dulatory, and many other interesting biological activities. Cepharanthine has been widely used in Japan for more than 40 years to treat a wide variety of acute and chronic diseases. CEP inhibits tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppresses cytokine production. It has also been shown to scavenge free radicals and to have a protective effect against some of the responses mediated by pro-inflammatory cytokines such as TNF-α, interleukin (IL)-1β and IL6. CEP has successfully been used to treat a diverse range of medical conditions, including radiation-induced leukopenia, idiopathic thrombocytopenic purpura, alopecia areata, alopecia pityrodes, venomous snakebites, xerostomia, sarcoidosis, refractory anemia and various cancer-related conditions. No safety issues have been observed with CEP, and side effects are very rarely reported. Uses: Anti-tumor/anti-inflammatory. Group: Pharmaceutical. CAS No. 481-49-2. Pack Sizes: 10 g. Product ID: NP0541. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cetrorelix diacetate | Cetrorelix is a gonadotropin-releasing hormone (GnRH) antagonist. Under the trade name Cetrotide, It is indicated for the inhibition of premature LH surges in women undergoing controlled ovarian stimulation. Group: Pharmaceutical. CAS No. 130143-01-0. Pack Sizes: 50 mg. Product ID: BAT-010074. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chrysophanol 1-O-glucoside | Chrysophanol 1-O-glucoside, an inherent component of diverse botanical species, boasts of paramount attention for its noteworthy anti-inflammatory and anti-tumor potentialities that have long been professed in traditional medicine. Its multifaceted pharmacological abilities have been under the researchers' radar, warranting potential deployment in treating metabolic maladies, liver afflictions, and obesity. Besides, this natural compound may stimulate the food and cosmetics industries with its remarkable antioxidant traits. Group: Pharmaceutical. CAS No. 4839-60-5. Pack Sizes: 5 mg. Product ID: NP0916. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CJC1295 With DAC | CJC1295 is a synthetic analogue of growth hormone-releasing hormone. Uses: cjc1295 with dac, also known as dac:grf (1-29), is a synthetic modification of the growth hormone releasing hormone (ghrh) peptide. this peptide is designed to stimulate the pituitary gland to produce and release growth hormone (gh) in a more sustained manner than natural ghrh. it contains a series of amino acids designed to mimic the effects of natural ghrh in the body. the addition of dac (dr. Group: Pharmaceutical. CAS No. 446262-90-4. Pack Sizes: 5 mg. Product ID: BAT-006154. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CL-387785 | CL-387785, also known as EKI-785, is an irreversible inhibitor of EGF-receptor (EGFR) kinase activity in vivo (IC50 = 250-490 pM). CL-387785 covalently bound to EGF-R. It also specifically inhibited kinase activity of the protein (IC50 = 370+/-120 pM), blocked EGF-stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31-125 nM) primarily in a cytostatic manner in cell lines that overexpress EGF-R or c-erbB-2, and profoundly blocked the growth of a tumor that overexpresses EGF-R in nude mice (when given orally at 80 mg/kg/day for 10 days, daily). CL-387,785 is useful for studying the interaction of small molecules with EGF-R and may have clinical utility. Uses: Protein kinase inhibitors. Group: Pharmaceutical. CAS No. 194423-06-8. Pack Sizes: 50 mg. Product ID: B0084-458793. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
