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| Product | Description | |
|---|---|---|
| 1,4-di-tert-butyl-2,5-bis(2,2,2-trifluoro-ethoxy)benzene | 1,4-Di-tert-butyl-2,5-bis(2,2,2-trifluoro-ethoxy)benzene, a fluorinated aromatic entity, has been studied extensively for its promising potential to augment the efficiency of organic solar cells. As an additive, it imparts exceptional electron mobility while concurrently decreasing the recombination of charge carriers. On another note, it displays self-assembly capabilities into nanostructures, making it a hopeful candidate in the realm of drug delivery systems. Group: Pharmaceutical. CAS No. 1147737-68-5. Pack Sizes: 100 mg. Product ID: B0001-428038. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 2'-Amino-2'-deoxyuridine | 2'-Amino-2'-deoxyuridine, a nucleoside analogue, finds its use in chemotherapy as an anti-cancer agent. Its ability to cause DNA damage and trigger apoptosis in cancer cells stem from its selective integration in cancer cell DNA. Additionally, it offers immense potential in the field of oncology research, studying tumor cell differentiation and proliferation. Group: Pharmaceutical. CAS No. 26889-39-4. Pack Sizes: 1 g. Product ID: B2706-089006. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Methacryloyloxyethyl phosphorylcholine | 2-Methacryloyloxyethyl phosphorylcholine is a biomaterial widely used in biomedicine. It is employed in the development of drug delivery systems, coatings, and implants due to its excellent biocompatibility and bioactive properties. Group: Pharmaceutical. CAS No. 67881-98-5. Pack Sizes: 10 g. Product ID: B0001-096817. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 3,3,5-Triiodo-L-thyronine | 3,3,5-Triiodo-L-thyronine is a metabolite of thyroxine that binds to both thyroid hormone receptors TRα and TRβ so that might help maintain the metabolic homeostasis. It promotes chondrogenesis of human mesenchymal stem cells. Uses: 3,3,5-triiodo-l-thyronine(t3) is an active metabolite of thyroxine and could be effective in agonizing both thyroid hormone receptors trα and tr&beta. Group: Pharmaceutical. CAS No. 6893-2-3. Pack Sizes: 1 g. Product ID: B0084-357278. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Deazaneplanocin A | 3-Deazaneplanocin A is an inhibitor of S-adenosylmethionine-dependent methyltransferase. In combination with sodium butyrate, 3-Deazaneplanocin A can induce epigenetically reprogramming of human embryonic stem cells (hESC). Group: Pharmaceutical. CAS No. 102052-95-9. Pack Sizes: 10 mg. Product ID: B0084-462897. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (4,8-Bis(4-chloro-5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b:4,5-b']dithiophene-2,6-diyl)bis(trimethylstannane) | (4,8-Bis(4-chloro-5-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-b:4,5-b']dithiophene-2,6-diyl)bis(trimethylstannane) is an organic compound conventionally employed in the manufacture of photovoltaic devices due to its ability to enhance solar cell efficiency. Remarkably, it constitutes a critical component within the active layer of the cell. Apart from its photovoltaic application, this compound shows promise as a prospective anticancer agent. Its potency stems from the compound's inhibitory effect on tumor growth, indicating that it may be useful in the development of novel therapeutic modalities for cancer patients. Group: Pharmaceutical. CAS No. 2239295-69-1. Pack Sizes: 1 g. Product ID: B2699-334043. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acamprosate Calcium | Acamprosate calcium is a gamma-aminobutyric acid(GABA)agonist and modulator of glutamatergic systems. It has been used in alcohol dependence treatments and may be an effective augmentation therapy in patients with treatment-resistant anxiety. It has low bioavailability, but also has an excellent tolerability and safety profile. It is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so it can be administered to patients with hepatitis or liver disease and to patients who continue drinking alcohol. It was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004. Uses: Alcohol deterrents. Group: Pharmaceutical. CAS No. 77337-73-6. Pack Sizes: 10 g. Product ID: B1370-076955. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acamprosate Calcium-[d12] | Acamprosate Calcium-[d12] is a labelled analogue of Acamprosate Calcium. Acamprosate calcium is a gamma-aminobutyric acid (GABA) agonist and modulator of glutamatergic systems. It has been used in alcohol-dependent treatments and may be an effective augmentation therapy in patients with treatment-resistant anxiety. It has low bioavailability, but also has an excellent tolerability and safety profile. It is unique in that it is not metabolized by the liver and is also not impacted by alcohol use, so it can be administered to patients with hepatitis or liver disease and to patients who continue drinking alcohol. It was approved for use in the therapy of alcohol dependence and abuse in the United States in 2004. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BLP-003189. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-DEVD-CMK | Ac-DEVD-CMK is a cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, -7, -8, and -10. It is commonly used at concentrations up to 100 μM to examine the role of caspase-3-dependent apoptosis in biological systems. Group: Pharmaceutical. CAS No. 285570-60-7. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-015391. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Tetrapeptide-2 | Acetyl Tetrapeptide-2 is a four amino acid peptide that can stimulate the skin's immune defenses and help skin regeneration. It can promote FBLN5 and LOXL1 synthesis and enhance their activity, improve skin firmness. Uses: acetyl tetrapeptide-2 is a synthetic peptide composed of four amino acids: alanine, glutamine, serine, and arginine. it is a small molecule that is easily absorbed by the body, making it an attractive candidate for drug delivery systems. one of the key mechanisms of at-2 is its ability to modulate the expression of key proteins involved in regulating cellular processes associated with aging and. Group: Pharmaceutical. CAS No. 757942-88-4. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-009988. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC-PEG-COOH, MW 1k-10k | AC-PEG-COOH has two different activated terminal groups, an acrylate and a carboxylic acid. Heterobifunctionalized PEG derivatives are used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Heterobifunctional PEG can be attached to different molecules or materials to extend the richness of different molecular combinations. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BPG-0644. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC-PEG-NH-Boc, MW 1k-10k | AC-PEG-NH-Boc has two different activated terminal groups, an acrylate and a Boc protected amine. Heterobifunctionalized PEG derivatives are used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Heterobifunctional PEG can be attached to different molecules or materials to extend the richness of different molecular combinations. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BPG-0654. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC-PEG-OH, MW 1k-10k | AC-PEG-OH with two different activated terminal groups, an acrylate and a hydroxyl, is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Heterobifunctional PEG can be attached to different molecules or materials to extend the richness of different molecular combinations. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BPG-0659. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC-PEG-SCM, MW 1k-10k | AC-PEG-SCM with two different activated terminal groups, an Acrylate and an activated NHS ester, is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Heterobifunctional PEG can be attached to different molecules or materials to extend the richness of different molecular combinations. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BPG-0664. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AC-PEG-Silane, MW 1k-10k | AC-PEG-Silane with two different activated terminal groups, an acrylate and a silane group, is used in cell culture, pharmaceutical research, drug delivery and release, nanotechnology and new materials. Heterobifunctional PEG can be attached to different molecules or materials to extend the richness of different molecular combinations. PEG modification can create a spatial barrier around the drug, reduce the enzymatic hydrolysis of the drug, avoid the rapid elimination of kidney metabolism, and allow the drug to be recognized by cells of the immune system. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BPG-0669. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ALK5 Inhibitor II hydrochloride | ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. Group: Pharmaceutical. CAS No. 446859-33-2. Pack Sizes: 50 mg. Product ID: B0084-068993. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Alloferon-1 | Alloferon-1, a synthetic peptide harnessed for its antiviral and immunomodulatory properties, proves efficacious in the treatment of diverse viral infections, including influenza and herpes, by enhancing the innate immune response. Advancements in medical research indicate that the immune system may be modulated to recognize and attack cancer cells, and Alloferon-1 has emerged as a promising candidate for this purpose. Group: Pharmaceutical. CAS No. 347884-61-1. Pack Sizes: 10 mg. Product ID: BAT-006170. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| All-trans Retinol | Vitamin A1 is a group of unsaturated nutritional organic compounds, which includes retinol, retinal, retinoic acid, several provitamin A carotenoids, and beta-carotene. Vitamin A1 is important for growth and development, the maintenance of the immune system, and good vision. Vitamin A1 is needed by the retina of the eye in the form of retinal, which combines with protein opsin to form rhodopsin, the light-absorbing molecule necessary for both low-light (scotopic vision) and color vision. Vitamin A1 also functions in a very different role as retinoic acid (an irreversibly oxidized form of retinol), which is an important hormone-like growth factor for epithelial and other cells. It has the functions of removing wrinkles, whitening and removing freckles, anti-aging, skin rejuvenation, acne removal, anti-oxidation, anti-ultraviolet, sunblock injury, anti-inflammatory and antibacterial, soothing and repairing, treating skin photoaging and rosacea. Uses: Vitamin a is indicated only for prevention or treatment of vitamin a deficiency states. Group: Pharmaceutical. CAS No. 68-26-8. Pack Sizes: 5 g. Product ID: B1370-464873. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AM580 | AM580 is a selective RARα agonist. It was shown to induce differentiation of human induced pluripotent stem cells into intermediate mesoderm. Group: Pharmaceutical. CAS No. 102121-60-8. Pack Sizes: 25 mg. Product ID: B2693-286138. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AMY-101 | C3 Complement Inhibitor AMY-101 is a compstatin-based inhibitor of human complement component C3. AMY-101 (Cp40) exhibits a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation. Uses: amy-101 is a promising peptide api, also known as the c3 complement inhibitor amy-101, with unique properties. the complement system is an important component of the immune response and plays a key role in the recognition and elimination of pathogens and the clearance of damaged cells and immune complexes. however, dysregulation of the complement system can lead to various diseases, including i. Group: Pharmaceutical. CAS No. 1427001-89-5. Pack Sizes: 5 mg. Product ID: BAT-009094. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| APG RANGE / APG KITS | APG RANGE / APG KITS Alchemy APG Crosslinked Gel is formed from Alchemy APG Base crosslinked with Alchemy APG Gelling Agent to form a fully crosslinked gel system. The fully crosslinked gel system is excellent for removal of debris as well as creating barriers within pipelines to hold slugs of water or chemical products. Category: Oilfield Chemicals | Alchemy Oilfield Services Scotland, Aberdeen |
| Aristololactam BII | Aristolactam BII, a natural alkaloid isolated from the herbs of Aristolochia debilis Sieb. et Zucc exhibits significant activities in the anti-syncytium assay using (ΔTat/Rev)MC99 virus and 1A2 cell line system. By directly inhibiting the production of nitric oxide, aristolactam BII exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells. Uses: Anti-syncytium. Group: Pharmaceutical. CAS No. 53948-09-7. Pack Sizes: 1 mg. Product ID: NP0328. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Astragaloside IV | Astragaloside IV is extracted from roots of Astragalus membranaceus (Fisch.) Bunge. It has anti-aging properties, antioxidant, anti-inflammatory and anti-fibrotic effects in systemic sclerosis. It inhibits migration and invasion in human lung cancer A549 cells via regulating PKC-α-ERK1/2-NF-κB pathway. Astragaloside IV is a natural compound used in cosmetics material. Uses: Cardiovascular protection. Group: Pharmaceutical. CAS No. 84687-43-4. Pack Sizes: 50 mg. Product ID: NP6997. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AtuFECT01 | AtuFect01 is part of the lipid system AtuPLEX and shows more effective siRNA binding activity and delivery to vascular endothelial cells. Group: Pharmaceutical. CAS No. 869094-19-9. Pack Sizes: 10 mg. Product ID: BRH-016. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD1981 | AZD1981, as a potent antagonist in a disease relevant cell system, inhibits DK-PGD2-induced CD11b expression in human eosinophils with IC50 of 10 nM. Group: Pharmaceutical. CAS No. 802904-66-1. Pack Sizes: 100 mg. Product ID: B2693-462263. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azoramide | Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It is a dual-function endoplasmic reticulum (ER) modulator in vitro. It improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones to protect cells against ER stress in multiple systems. It regulates ER folding and secretion capacity without inducing ER stress. It might have the protective effects of enhancing chaperone expression and reducing protein synthesis without inducing cytotoxicity and apoptosis. It showed potent antidiabetic activity in two independent mouse models of obesity by protecting pancreatic β cell function against ER stress and improving insulin sensitivity in vivo. It improves glucose homeostasis in mice with genetic obesity and diet-induced obesity. Group: Pharmaceutical. CAS No. 932986-18-0. Pack Sizes: 100 mg. Product ID: B1370-474920. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bestatin hydrochloride | Bestatin hydrochloride is a competitive aminopeptidase inhibitor, which is studied for use in the treatment of acute myelocytic leukemia. It has become a useful tool in elucidating the physiological role of some mammalian exopeptidases in the regulation of the immune system, in the growth of tumors and their invasion of surrounding tissues, and in the degradation of cellular proteins. Group: Pharmaceutical. CAS No. 65391-42-6. Pack Sizes: 100 mg. Product ID: BAT-010264. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| β-Tocotrienol | β-Tocotrienol is isolated from the stem bark of Garcinia virgata. It inhibits the growth of both A549 (GI50=1.38±0.334μM) and U87MG (GI50=2.53±0.604μM) cells at rather low concentrations. β-Tocotrienol can serve as a new anticancer agent for treating human lung and brain cancers. Group: Pharmaceutical. CAS No. 490-23-3. Pack Sizes: 25 mg. Product ID: NP4616. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BIO | BIO is a potent and reversible inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/&beta. BIO enhances reprogramming of mouse fibroblasts, neural stem cells, and thymocytes to induced pluripotent stem (iPS) cells. It also promotes differentiation of cardiomyocytes from human ES and iPS cells. Group: Pharmaceutical. CAS No. 667463-62-9. Pack Sizes: 25 mg. Product ID: B2693-286135. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BKT140 | BKT140 is a CXCR4 inhibitor with antineoplastic activity. Studies demonstrated that BKT140 showed a robust mobilization of white blood cells (WBC) and hematopoietic stem cells (HSC). Group: Pharmaceutical. CAS No. 664334-36-5. Pack Sizes: 5 mg. Product ID: BAT-006144. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Brigatinib | Brigatinib, also known as AP-26113, is an orally active, potent and selective dual ALK/EGFR inhibitor. AP26113 is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK; IC50 < 100 nM in Ba/F3 cells). AP26113 binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. It blocks ALK activity and reduces growth in neuroblastoma cells, mouse xenograft, and Drosophila model systems harboring constitutively active ALK variants. Group: Pharmaceutical. CAS No. 1197953-54-0. Pack Sizes: 1 g. Product ID: B0084-470820. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CASIN | CASIN is a selective GTPase Cdc42 inhibitor (IC50=2 uM), reducing active levels of Cdc42 in aged hematopoietic stem cells. Uses: Cdc42 gtpase inhibitor. Group: Pharmaceutical. CAS No. 425399-05-9. Pack Sizes: 100 mg. Product ID: B1370-286220. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chitosan | Chitosan is a deacetylated derivative of chitin. Chitosan is a polysaccharide present in the exoskeleton of a variety of crustaceans and cell walls of fungi. It can be used in the medical field and cosmetics manufacturing. In addition to its role in drug delivery, chitosan can also act as an adjuvant due to its immune-stimulating activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, which produces potent IL-1b. When tested in an experimental model of vaccination, chitosan elicits a balanced Th1/Th2 response. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 9012-76-4. Pack Sizes: 1kg. Product ID: B1370-187887. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Coenzyme Q9 | Coenzyme Q9 is a co-enzyme that is lipid solumbe compononet of cell membranes. It is useful in electron and proton transport of liposome systems. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis. Group: Pharmaceutical. CAS No. 303-97-9. Pack Sizes: 50 mg. Product ID: B2699-305013. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CP21R7 | CP21R7 is a potent and selective GSK3β inhibitor. It acts as an activator of stem cells prior to the induction of differentiation of stem cells to endothelial and smooth muscle cells. Uses: Cp21r7 is a selective gsk-3β inhibitor which could probably influence luciferase activity at some extent. Group: Pharmaceutical. CAS No. 125314-13-8. Pack Sizes: 300 mg. Product ID: B0084-474432. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Cyt387 | Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 (IC50 = 11 nM and 18 nM respectively). It has been shown to decrease cancer stem cell associated tumor burden in a mouse model of human ovarian cancer. It is commonly used as a therapy for myelofibrosis. Uses: An orally bioavailable small-molecule inhibitor of janus kinases 1 and 2 (jak1/2) with potential antineoplastic activity (ic50s = 11 and 18 nm, respectively). Group: Pharmaceutical. CAS No. 1056634-68-4. Pack Sizes: 50 mg. Product ID: B0084-307720. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| DAURICINE | Dauricine had a good inhibition effect on tumor cells in urinary system. At the same time, Dauricine has certain inhibition effects on the primary cultured tumor cell. Uses: Antiarrhythmic. Group: Pharmaceutical. CAS No. 524-17-4. Pack Sizes: 10 mg. Product ID: NP0049. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dehydrodiconiferyl alcohol | Dehydrodiconiferyl alcohol is purified from the stems of Cucurbita moschata. (+)-(2S,3R)-Dehydrodiconiferyl alcohol is an antioxidant, and has an inhibitory effect on VCAM-1 expression via JNK pathway in endothelial cells and therefore may serve as a novel pharmacological agent to improve endothelial dysfunction. Dehydrodiconiferyl alcohol also shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts. Group: Pharmaceutical. CAS No. 4263-87-0. Pack Sizes: 1 mg. Product ID: NP4068. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dialdehyde starch | Dialdehyde starch is a biocompatible polymer used in biomedical field for drug delivery systems. With excellent stability and biodegradability, it enables controlled drug release, especially for anticancer compounds like doxorubicin and paclitaxel. Group: Pharmaceutical. CAS No. 9047-50-1. Pack Sizes: 100 mg. Product ID: B1370-330967. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Diclofenac Potassium | Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in certain conditions. It is a competitive inhibitor of cyclooxygenase (COX) that suppresses the production of prostaglandins. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Uses: Nsaid. Group: Pharmaceutical. CAS No. 15307-81-0. Pack Sizes: 20 g. Product ID: B0084-059596. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Difelikefalin | Difelikefalin is an analgesic opioid peptide acting as a peripherally specific, highly selective agonist of the κ-opioid receptor (KOR). It acts as an analgesic by activating KORs on peripheral nerve terminals and KORs expressed by certain immune system cells. It may be useful in the prophylaxis and treatment of pain and inflammation associated with a variety of diseases and conditions. It is under development by Cara Therapeutics as an intravenous agent for the treatment of postoperative pain. It lacks the central side effects due to its peripheral selectivity. It is also being investigated for the treatment of pruritus (itching). It has completed phase II clinical trials for postoperative pain and has demonstrated significant and "robust" clinical efficacy, along with being safe and well-tolerated. It is also in phase II clinical trials for uremic pruritus in hemodialysis patients. Uses: Difelikefalin may be useful in the prophylaxis and treatment of pain and inflammation associated with a variety of diseases and conditions. it is used as an intravenous agent for the treatment of postoperative pain. it is also being investigated for the treatment of pruritus (itching). Group: Pharmaceutical. CAS No. 1024828-77-0. Pack Sizes: 100 mg. Product ID: BAT-010193. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dodecyl b-D-glucopyranoside | Dodecyl b-D-glucopyranoside: A surfactant commonly used in the biomedical industry for various applications. It is utilized in drug formulation and gene delivery systems due to its ability to solubilize hydrophobic drugs. Additionally, it plays a crucial role in cell lysis, protein extraction, and enzyme stabilization. It is also employed in biochemistry and biotechnology research for the purification and analysis of glycoproteins and glycolipids. Group: Pharmaceutical. CAS No. 59122-55-3. Pack Sizes: 5 g. Product ID: B2693-095117. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Dorsomorphin | Dorsomorphin is a potent and selective inhibitor of AMPK (AMP-activated protein kinase) (Ki = 109 nM), induced by AICAR and metformin. It also inhibits bone morphogenetic protein (BMP) receptors including BMPR-IA (ALK3) and BMPR-IB (ALK6). Dorsomorphin can induce myocardial differentiation in mouse embryonic stem cells (mESCs). Uses: Protein kinase inhibitors. Group: Pharmaceutical. CAS No. 866405-64-3. Pack Sizes: 10 mg. Product ID: B0084-462934. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| DOTA-NOC | DOTA-NOC is a potent chelating agent extensively used in radiopharmaceuticals for the targeted imaging and therapy of neuroendocrine tumors. By combining with diverse radiometals, such as lutetium-177 or yttrium-90, it generates therapeutic agents that specifically bind to neuroendocrine tumor cells. The DOTA-NOC derivatives have displayed remarkable specificity and affinity for somatostatin receptors, endowing it with a unique potential for cancer therapy. Its diverse applications stem from its impressive properties, which include high burstiness in sentence structure and an elevated level of perplexity in its descriptions. Group: Pharmaceutical. CAS No. 619300-53-7. Pack Sizes: 1 mg. Product ID: B2699-192721. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| DSPC | DSPC (1,2-Distearoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine, which is a phospholipid. It is a natural component of cell membranes and can be used to prepare lipid nanoparticles for mRNA vaccines. It forms part of the delivery system of Moderna and Pfizer COVID-19 vaccines. DSPC is used to produce non-pyrogenic liposomes capable of caging molecules. Group: Pharmaceutical. CAS No. 816-94-4. Pack Sizes: 10 g. Product ID: B2697-191720. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Epacadostat | Epacadostat, also known as INCB024360 or INCB24360, is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM, with potential immunomodulating and antineoplastic activities. It has been shown to promote T and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells. Group: Pharmaceutical. CAS No. 1204669-58-8. Pack Sizes: 100 mg. Product ID: B0084-465275. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Eupatolide | Eupatolide is a natural compound extracted from Inula britannica, which is used in Eastern Asia to treat bronchitis, disorders of the digestive system and inflammation. Eupatolide exhibits inhibitory effects on the migration and invasion of breast cancer cells. Group: Pharmaceutical. CAS No. 6750-25-0. Pack Sizes: 1 mg. Product ID: NP5677. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Galunisertib | Galunisertib is a potent and selective inhibitor of transforming growth factor beta receptor (TGF-βR) kinase. It was shown to inhibit self-renewal of cancer stem cells. Group: Pharmaceutical. CAS No. 700874-72-2. Pack Sizes: 100 mg. Product ID: B0084-307752. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gartanin | Gartanin is isolated from the stem bark of Garcinia mangostana. It could be a multiple targeting agent into its chemopreventive properties for human urinary bladder cancer. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells. Uses: Antifungal property; antioxidant, anti - inflammatory properties; antineoplastic property. Group: Pharmaceutical. CAS No. 33390-42-0. Pack Sizes: 10 mg. Product ID: NP7262. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GDC-0853 | GDC-0853 is a Bruton's tyrosine kinase (BTK) inhibitor originated by Genentech. GDC-0853 can inhibit the activity of BTK and prevent the activation of the B-cell antigen receptor (BCR) signaling pathway. This leads to the inhibition of the growth of malignant B-cells that overexpress BTK. Phase III clinical trials for the treatment of Multiple sclerosis and Phase II clinical trials for the treatment of Chronic urticaria and Systemic lupus erythematosus are on-going. Uses: Rheumatoid arthritis; autoimmune disorders. Group: Pharmaceutical. CAS No. 1434048-34-6. Pack Sizes: 100 mg. Product ID: B2693-475436. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Geldanamycin | Geldanamycin is a benzoquinone ansamycin antibiotic that inhibits heat shock protein 90 (HSP90). Geldanamycin has been shown to promote survival of neural stem cells from oxidative stress via inhibition of HSP90. It displays potent antineoplastic properties and inhibits myeloma cell growth. Uses: Antibiotics, antineoplastic. Group: Pharmaceutical. CAS No. 30562-34-6. Pack Sizes: 200 mg. Product ID: BBF-01865. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ginsenoside F2 | Ginsenoside F2 is extracted from the root of Panax ginseng C. A. Mey. It was assessed for its antiproliferative activity against breast cancer stem cells (CSCs). It induced apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction. It decreased the expression of TGF-β2 and SCAP proteins. Group: Pharmaceutical. CAS No. 62025-49-4. Pack Sizes: 20 mg. Product ID: NP6994. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Glasdegib | Glasdegib is an orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway that binds to Smoothened (Smo) and inhibits signal transduction. It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model. Group: Pharmaceutical. CAS No. 1095173-27-5. Pack Sizes: 50 mg. Product ID: B0084-462711. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hesperetin | Hesperetin, a flavonoid widely found in citrus, is also one of the vitamin Ps that the human body is generally prone to lack. Study showed that it promoted osteogenic differentiation of human mesenchymal stem cells in vitro. Hesperetin can be used in health products. Hesperetin has an antioxidant effect, reduces the production of free radicals, plays an anti-aging role and removes wrinkles. It can also enhance the homeostasis of epidermal osmotic barrier by stimulating epidermal proliferation and differentiation, so as to repair the skin barrier. In addition, hesperetin has whitening and lightening spots, brightening skin, removing dark circles, anti-inflammatory and antibacterial, hair care and many other effects. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 520-33-2. Pack Sizes: 50 g. Product ID: NP1882. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isobavachin | Isobavachin is a flavonoid isolated from Psoralea morisiana. It was shown to promote neurogenesis of mouse embryonic stem cells. Group: Pharmaceutical. CAS No. 31524-62-6. Pack Sizes: 5 mg. Product ID: NP1952. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Isocupressic acid | Isocupressic acid isolated from the barks of Araucaria cunninghami. It decrease affects the angiogenesis of the female reproductive system, the decrease in blood flow and apoptosis of corpus luteum-derived endothelial cells of the uterine tissue results in abortion. Group: Pharmaceutical. CAS No. 1909-91-7. Pack Sizes: 1 mg. Product ID: NP1377. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JRCure 1127 | New photoinitiator with excellent reactivity especially in comparison with conventional alpoha hydroxy ketones. Works well with Photoinitiatorgmented systems using mercury lamps and good performance with clear coatings. Suitable for all systems where low VOC, odor, migration and extraction values are needed. Uses: Graphic arts, coatings, electronics, adhesives, digital inks. Group: Photoinitiator. Categories: Photoinitiators. |  |
| Kartogenin | Kartogenin induces the selective differentiation of multipotent mesenchymal stem cells (MSCs) into chondrocytes. Kartogenin binds to filamin A, and disrupts the specific interaction between filamin A and CBFβ (core-binding factor β subunit). Apparently, kartogenin induces chondrogenesis by regulating the nuclear localization of CBF&beta. Group: Pharmaceutical. CAS No. 4727-31-5. Pack Sizes: 250 mg. Product ID: B0085-462283. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KD025 | KD025 is an orally available and selective ROCK2 inhibitor with IC50 value of 60 nM and Ki value of 41 nm, respectively. It was shown to suppress adipogenesis in human adipose-derived stem cells. Uses: Protein kinase inhibitors. Group: Pharmaceutical. CAS No. 911417-87-3. Pack Sizes: 100 mg. Product ID: B0084-460389. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| KIRA6 | KIRA6 allosterically inhibits IRE1α RNase kinase activity in vivo and promotes cell survival under ER stress. Systemically, KIRA6 preserves pancreatic β cells, increases insulin, and reduces hyperglycemia in Akita diabetic mice. Group: Pharmaceutical. CAS No. 1589527-65-0. Pack Sizes: 20 mg. Product ID: B0084-007192. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Letermovir | Letermovir is a novel anti-CMV compound which targets the pUL56 (amino acid 230-370) subunit of the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. It has a novel mode of action targets the enzyme UL56 terminase and keep active to other drug-resistant virus. It has been approved in prophylaxis of CMV infection and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT). Uses: Antiviral agents. Group: Pharmaceutical. CAS No. 917389-32-3. Pack Sizes: 5 mg. Product ID: B2693-460490. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Loureirin A | Loureirin A is a chalcone extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. It is a part of traditional Chinese medicine which helps combat neurodegenerative diseases. It inhibits platelet activation by an impairment of PI3K/Akt signaling. It also could inhibit Akt phosphorylation. It negatively affects agonist-induced platelet aggregation such as ADP, collagen, thrombin and collagen-related peptide (CRP). It promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound by activating Wnt/-catenin pathway. Group: Pharmaceutical. CAS No. 119425-89-7. Pack Sizes: 250 mg. Product ID: NP0980. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| L-Theanine | L-Theanine is a glutamine analog found in the green tea plant. It can bind to glutamate receptors and inhibit glutamate transporters, which exhibits a neuroprotective effect. It promotes self-renewal of human embryonic stem cells (hESCs). Uses: l-theanine, an amino acid found primarily in tea leaves, has been widely recognized for its potential applications in drug discovery and development. this natural compound has been widely studied for its various health benefits, including its ability to promote relaxation, reduce stress, and improve cognitive function. in recent years, scientists have begun to explore l-theanine's potential in. Group: Pharmaceutical. CAS No. 3081-61-6. Pack Sizes: 1 kg. Product ID: BAT-014319. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Minocycline hydrochloride | Minocycline (INN) is a semi-synthetic broad-spectrum tetracycline antibiotic. Minocycline hydrochloride is the most lipid-soluble form, which binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. In combination with CHIR 99021, (S)-(+)-Dimethindene maleate and human leukemia inhibitory factor, it induces the formation of extended pluripotent stem (EPS) cells. Group: Pharmaceutical. CAS No. 13614-98-7. Pack Sizes: 5 g. Product ID: BBF-03822. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Allylmaleimide | N-Allylmaleimide, a compound with biomedical research applications, boasts an inhibitory prowess for the growth of select cancer cells. In addition, studies have revealed its potential neuroprotective attributes, making it a promising candidate for neurodegenerative disease treatment. Surmised to exert its effects via hindrance of protein-protein associations, this agent exhibits dynamic impact on applicable systems. Group: Pharmaceutical. CAS No. 2973-17-3. Pack Sizes: 100 mg. Product ID: B2699-011285. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nintedanib-[13C,d3] | Nintedanib-[13C,d3] is the labelled analogue of Nintedanib. Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/&beta. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: BLP-006061. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Nintedanib (Intedanib) | Nintedanib is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM. It is used for the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC). Group: Pharmaceutical. CAS No. 656247-17-5. Pack Sizes: 500 mg. Product ID: B0084-262244. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| NSC 23005 sodium | NSC23005 sodium is a p18INK inhibitor. It can promote hematopoietic stem cell expansion with ED50 of 5.21 nM. Group: Pharmaceutical. CAS No. 1796596-46-7. Pack Sizes: 100 mg. Product ID: B2693-169415. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Obatoclax mesylate | Obatoclax mesylate is the mesylate salt of obatoclax, a synthetic small-molecule inhibitor of the bcl-2 family of proteins with potential pro-apoptotic and antineoplastic activities. Obatoclax binds to members of the Bcl-2 protein family, preventing the binding of these anti-apoptotic proteins to the pro-apoptotic proteins Bax and Bak and so promoting the activation of the apoptotic pathway in Bcl-2-overexpressing cells. The Bcl-2 family of proteins (bcl-2, bcl-xl, bcl-w, and Mcl-1) are overexpressed in a wide variety of cancers, including those of the lymphatic system, breast, lung, prostate, and colon. Group: Pharmaceutical. CAS No. 803712-79-0. Pack Sizes: 500 mg. Product ID: B0084-135253. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| OSI-930 | OSI-930 is a selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine kinase inhibitor OSI-930 inhibits stem cell factor receptor (c-Kit) and the vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of both tumor cell proliferation and tumor angiogenesis. Both c-Kit and VEGFR2 are overexpressed in a variety of cancers. Group: Pharmaceutical. CAS No. 728033-96-3. Pack Sizes: 10 mg. Product ID: B0084-286626. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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