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| Product | Description | |
|---|---|---|
| Staurosporine | Staurosporine, also known as antibiotic AM-2282 or STS, is a broad spectrum protein kinase inhibitor produced by Streptomyces sp. Enzymes inhibited include protein kinase C (IC50 = 3 nM), protein kinase A (IC50 = 7 nM), p60v-src tyrosine protein kinase (IC50 = 6 nM) and CaM kinase II (IC50 = 20 nM). Staurosporine was discovered to have biological activities ranging from anti-fungal to anti-hypertensive. Group: Pharmaceutical. Alternative Names: NSC 25485; 2,3,10,11,12,13-hexahydro-10R-methoxy-9S-methyl-11R-methylamino-9S,13R-epoxy-1H,9H-diindolo[1,2,3-gh; 3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one; NSC-25485; NSC25485. CAS No. 62996-74-1. Pack Sizes: 25 mg. Product ID: BBF-03921. Molecular formula: C28H26N4O3. Mole weight: 466.53. Custom synthesis is available. Send your inquiries for more information. |  London |
| Staurosporine, streptomyces staurosporeus | 5mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C28H26N4O3. CAS No. 62996-74-1. Prepack ID : 16881725-5mg. Molecular Weight : 466.53. |  |
| K252A | K252a, an analog of staurosporine, has been found to be a protein kinase inhibitor and exhibit antitumor activity at some extent. Group: Pharmaceutical. Alternative Names: NZ0550000; Antibiotic K 252a. CAS No. 99533-80-9. Pack Sizes: 50 mg. Product ID: BBF-04182. Molecular formula: C27H21N3O5. Mole weight: 467.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Midostaurin | Midostaurin is a multi-target protein kinase inhibitor being investigated for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It is a semi-synthetic derivative of staurosporine, an alkaloid from the bacterium Streptomyces staurosporeus. Group: Pharmaceutical. Alternative Names: PKC412; PKC-412; PKC 412; PKC412A; PKC-412A; PKC 412A; CGP41251; CGP 41251; CGP-41251; Benzoylstaurosporine; 4'-N-Benzoylstaurosporine. CAS No. 120685-11-2. Pack Sizes: 20 mg. Product ID: BBF-05737. Molecular formula: C35H30N4O4. Mole weight: 570.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Nardosinone | Nardosinone, coming from the roots of Nardostachys jatamansi DC, enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and staurosporine. It could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. Uses: Antidepressant/sedative. Group: Pharmaceutical. Alternative Names: (3aR)-1,3aβ,4,7,8,9,9a,9bβ-Octahydro-1,1,9β,9aβ-tetramethyl-5H-naphtho[2,1-c][1,2]dioxol-5-one; 1,1,9β,9aβ-Tetramethyl-3aβ,7,8,9,9a,9bβ-hexahydro-1H-naphtho[2,1-c][1,2]dioxole-5(4H)-one; (3aR,9R,9aR,9bS)-1,3a,4,7,8,9,9a,9b-Octahydro-1,1,9,9a-tetramethyl-5H-naphtho[2,1-c][1,2]dioxol-5-one; 5H-Naphtho[2,1-c][1,2]dioxol-5-one,1,3a,4,7,8,9,9a,9b-octahydro-1,1,9,9a-tetramethyl-, (3aR,9R,9aR,9bS)-. CAS No. 23720-80-1. Pack Sizes: 50 mg. Product ID: NP5946. Molecular formula: C15H22O3. Mole weight: 250.33. Custom synthesis is available. Send your inquiries for more information. | London |
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