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1-benzyl-4-ethoxybenzene is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: Benzene,1-ethoxy-4-(phenylmethyl)-; 1-benzyl-4-ethoxy-benzene. CAS No. 35672-52-7. Pack Sizes: 100 mg. Product ID: B1370-377700. Molecular formula: C15H16O. Mole weight: 212.29. Custom synthesis is available. Send your inquiries for more information.
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A-317491
A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Uses: P2x3 and p2x2/3 receptor antagonist. Group: Pharmaceutical. Alternative Names: ABT 202; A-317491 sodium; ABT202; A317491 sodium; ABT-202; A 317491 sodium; 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid. CAS No. 475205-49-3. Pack Sizes: 1mg;1g;10g. Product ID: 475205-49-3. Molecular formula: C33H27NO8. Mole weight: 565.57. Custom synthesis is available. Send your inquiries for more information.
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ABT-080
ABT-080 is a leukotriene synthesis inhibitor potentially for the treatment of asthma. Group: Pharmaceutical. Alternative Names: Benzenebutanoic acid, γ-methyl-4-(2-quinolinylmethoxy)-γ-[4-(2-quinolinylmethoxy)phenyl]-, sodium salt (1:1); Benzenebutanoic acid, γ-methyl-4-(2-quinolinylmethoxy)-γ-[4-(2-quinolinylmethoxy)phenyl]-, monosodium salt; 4,4-bis(4-(2-quinolylmethoxy)phenyl)pentanoic acid sodium salt; ABT 080; ABT080; VML 530; VML530; VML-530. CAS No. 189498-57-5. Pack Sizes: 1mg;1g;10g. Product ID: 189498-57-5. Molecular formula: C37H31N2NaO4. Mole weight: 590.64. Custom synthesis is available. Send your inquiries for more information.
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Amfenac-[d5] Sodium Salt
Amfenac-[d5] Sodium Salt is a labelled sodium compound of Amfenac. Amfenac is a COX inhibitor with IC50 of 0.25 and 0.15 μM for COX-1 and COX-2, respectively. Group: Pharmaceutical. Alternative Names: 2-Amino-3-(benzoyl-d5)benzeneacetic Acid Sodium Salt. Pack Sizes: 10 mg. Product ID: B1370-288361. Molecular formula: C15H7D5NNaO3. Mole weight: 282.28. Custom synthesis is available. Send your inquiries for more information.
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Canagliflozin
Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity. Group: Pharmaceutical. Alternative Names: D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, (1S)-; JNJ-24831754; TA-7284; JNJ 24831754; TA 7284; JNJ24831754; TA7284; (1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol; (2S,3R,4R,5S,6R)-2-(3-((5-(4-Fluorophenyl)thien-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; 1-(β-D-Glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene; Invokana; JNJ 24831754ZAE; JNJ 28431754AAA. CAS No. 842133-18-0. Pack Sizes: 1 g. Product ID: NP3628. Molecular formula: C24H25FO5S. Mole weight: 444.52. Custom synthesis is available. Send your inquiries for more information.
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Canagliflozin hemihydrate
Canagliflozin hemihydrate is a highly potent and selective inhibitor of subtype 2 sodium-glucose transport protein (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. It is an experimental drug being developed by Johnson & Johnson for the treatment of type 2 diabetes. Uses: The potential treatment of type 2 diabetes. Group: Pharmaceutical. Alternative Names: (3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol hemihydrate; JNJ 28431754 hemihydrate; TA 7284 hemihydrate; JNJ-24831754-ZAE hemihydrate; JNJ-28431754-AAA hemihydrate; (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol hydrate (2:1); Cagliflozin hydrate; Invokana hemihydrate; 1-(β-D-Glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene hemihydrate. CAS No. 928672-86-0. Pack Sizes: 1 g. Product ID: B0084-463685. Molecular formula: C24H25FO5S.1/2H2O. Mole weight: 453.53. Custom synthesis is available. Send your inquiries for more information.
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Dapagliflozin Impurity 17
Dapagliflozin Impurity 17 is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Group: Pharmaceutical. Alternative Names: 1,4-Dibromo-2-[(4-ethoxyphenyl)methyl]benzene. CAS No. 1807632-93-4. Pack Sizes: 50 mg. Product ID: B2694-352570. Molecular formula: C15H14Br2O. Mole weight: 370.08. Custom synthesis is available. Send your inquiries for more information.
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Diclofenac EP Impurity C
Diclofenac EP Impurity C is an impurity of Diclofenac, which is a non-selective COX inhibitor used as a non-steroidal anti-inflammatory drug (NSAID). Group: Pharmaceutical. Alternative Names: Diclofenac sodium EP impurity C; Diclofenac potassium EP impurity C; Diclofenac Impurity C; [2-[(2,6-dichlorophenyl)amino]phenyl]methanol; 2-[(2,6-Dichlorophenyl)amino]benzenemethanol; Diclofenac Alcohol (Diclofenac Impurity); Benzenemethanol, 2-[(2,6-dichlorophenyl)amino]-; Benzyl alcohol, o-(2,6-dichloroanilino)-; Diclofenac alcohol analog. CAS No. 27204-57-5. Pack Sizes: 100 mg. Product ID: B2694-470082. Molecular formula: C13H11Cl2NO. Mole weight: 268.14. Custom synthesis is available. Send your inquiries for more information.
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Fenoprofen sodium salt dihydrate
Fenoprofen sodium salt is a nonsteroidal anti-inflammatory drug used to treat mild to moderate pain, osteoarthritis, or rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: α-Methyl-3-phenoxybenzeneacetic Acid Sodium Salt Dihydrate; (±)-α-Methyl-3-phenoxybenzeneacetic Acid Sodium Salt Dihydrate; Fenoprofen sodium salt hydrate; Benzeneacetic acid, α-methyl-3-phenoxy-, sodium salt, hydrate (1:1:2); Benzeneacetic acid, α-methyl-3-phenoxy-, sodium salt, dihydrate; Benzeneacetic acid, α-methyl-3-phenoxy-, sodium salt, dihydrate, (±)-. CAS No. 66424-46-2. Pack Sizes: 10 g. Product ID: B2692-152391. Molecular formula: C15H13NaO3.2H2O. Mole weight: 300.28. Custom synthesis is available. Send your inquiries for more information.
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Sodium 4-Phenylbutyrate-[d11]
Sodium 4-Phenylbutyrate-[d11] is a labelled salt form of 4-Phenylbutyrate, which is an HDAC inhibitor. Sodium 4-Phenylbutyrate-[d11] is intended for use as an internal standard for the quantification of sodium 4-phenylbutyrate by GC- or LC-MS. Group: Pharmaceutical. Alternative Names: Benzenebutanoic acid-d11; TriButyrate-d11; Benzene-d5-butanoic-d6 acid monosodium salt. CAS No. 1392208-11-5. Pack Sizes: 10 mg. Product ID: B1370-291688. Molecular formula: C10D11NaO2. Mole weight: 197.25. Custom synthesis is available. Send your inquiries for more information.
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Sulfadiazine Sodium
Sulfadiazine sodium is a bacteriostatic sulfonamide antibiotic. It is used to treat systemic infections caused by sensitive bacteria in domestic animals, such as respiratory and urinary tract infections and mastitis, uterine sarcoiditis, peritonitis, etc. It is also effective for swine toxoplasmosis. Group: Pharmaceutical. Alternative Names: (n(sup1)-2-pyrimidinylsulfanilamido)-sodium; 2-sulfanilamidopyrimidine sodium salt; 4-amino-n-2-pyrimidinyl-benzenesulfonamidmono sodium salt; monosodium 2-sulfanilamidopyrimidine; n(sup1)-2-pyrimidinylsulfanilamide monosodium salt. CAS No. 547-32-0. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03899. Molecular formula: C10H9N4NaO2S. Mole weight: 272.26. Custom synthesis is available. Send your inquiries for more information.
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Tenapanor
This active molecular is an sodium-proton exchanger NHE3 inhibitor under the development of Ardelyx. This antiporter protein plays a really important role in sodium handling in the gastrointestinal tract and kidney and it regulates the levels of sodium absorbed and secreted by the body. Therefore, tenapanor can be useful in the treatment of chronic kidney disease and hypertension because both of them are exacerbated by excess sodium in the diet. In Oct 2016, Phase-III clinical trials in Hyperphosphataemia (in patients with end-stage renal disease) in USA was on going. Uses: Hyperphosphataemia. Group: Pharmaceutical. Alternative Names: 3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-((3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide; AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; Tenapanor free base. CAS No. 1234423-95-0. Pack Sizes: 25 mg. Product ID: B0084-475197. Molecular formula: C50H66Cl4N8O10S2. Mole weight: 1145.04. Custom synthesis is available. Send your inquiries for more information.
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Tenapanor HCl
Tenapanor, also known as AZD-1722 and RDX 5791, is a first-in-class, small-molecule inhibitor of the gastrointestinal sodium/hydrogen exchanger NHE3. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects. Tenapanor acts in the gastrointestinal tract to reduce the absorption of sodium and phosphate, with minimal systemic drug exposure. Group: Pharmaceutical. Alternative Names: 3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)-N-(26-((3-((S)-6,8-dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)phenyl)sulfonamido)-10,17-dioxo-3,6,21,24-tetraoxa-9,11,16,18-tetraazahexacosyl)benzenesulfonamide dihydrochloride; AZD-1722; AZD 1722; AZD1722; RDX 5791; RDX-5791; RDX5791; Tenapanor; Tenapanor hydrochloride; Tenapanor dihydrochloride. CAS No. 1234365-97-9. Pack Sizes: 50 mg. Product ID: B2693-007851. Molecular formula: C50H68Cl6N8O10S2. Mole weight: 1217.9. Custom synthesis is available. Send your inquiries for more information.
London
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