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Simvastatin is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM. Group: Pharmaceutical. Alternative Names: Nodinitib-1; Zocor; Synvinolin; MK-733; Sinvacor; MK 733; MK733. CAS No. 79902-63-9. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04045. Molecular formula: C25H38O5. Mole weight: 418.57. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin Acyl-β-D-glucuronide
A metabolite of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Uses: The treatment of acute hyperammonemia. Group: Pharmaceutical. Alternative Names: Simvastatin Acyl-beta-D-glucuronide; 1-[(βR,δR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoate] β-D-Glucopyranuronic Acid. CAS No. 463962-56-3. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008114. Molecular formula: C31H48O12. Mole weight: 612.71. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin-[d3]
An isotope labelled of Simvastin. Simvastatin is a lipid-lowering medication and the primary uses of simvastatin are to treat dyslipidemia. Group: Pharmaceutical. Alternative Names: Simvastatin D3 lactone. CAS No. 1002347-61-6. Pack Sizes: 50 mg. Product ID: BLP-013128. Molecular formula: C25H35D3O5. Mole weight: 421.58. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin EP Impurity B
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Acetyl simvastatin; 4'-Acetyl Simvastatin; Simvastatin Acetate; Simvastatin acetate ester; Simvastatin USP Related Compound B. CAS No. 145576-25-6. Pack Sizes: 100 mg. Product ID: B2694-223423. Molecular formula: C27H40O6. Mole weight: 460.62. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin EP Impurity C
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Simvastatin USP Related Compound C; 2,3-Anhydro Simvastatin; Dehydro Simvastatin; Anhydro simvastatin. CAS No. 210980-68-0. Pack Sizes: 100 mg. Product ID: B2694-260207. Molecular formula: C25H36O4. Mole weight: 400.56. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin EP Impurity D
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Simvastatin USP Related Compound D; Simvastatin Dimer. CAS No. 476305-24-5. Pack Sizes: 10 mg. Product ID: B2694-263916. Molecular formula: C50H76O10. Mole weight: 837.13. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin EP Impurity F
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Simvastatin USP Related Compound F; epi-Lovastatin; Lovastatin epimer; (2R)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. CAS No. 79952-44-6. Pack Sizes: 50 mg. Product ID: B2694-261180. Molecular formula: C24H36O5. Mole weight: 404.55. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin EP Impurity G
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Methylene Simvastatin; 2''-Desethyl-2''-vinyl Simvastatin; Simvastatin USP Related Compound G. CAS No. 1449248-72-9. Pack Sizes: 25 mg. Product ID: B2694-479627. Molecular formula: C25H36O5. Mole weight: 416.56. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin EP Impurity H
An intermediate in the synthesis of Simvastatin, Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Lovastatin Lactone Diol; Monacolin J; Antibiotic MB 530A; 6(R)-[2-(8(S)-Hydroxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one. CAS No. 79952-42-4. Pack Sizes: 50 mg. Product ID: B2694-257205. Molecular formula: C19H28O4. Mole weight: 320.43. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin EP Impurity I
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: 2'-Ethyl Simvastatin. CAS No. 79902-42-4. Pack Sizes: 10 mg. Product ID: B2694-334169. Molecular formula: C23H34O5. Mole weight: 390.51. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin EP Impurity J
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Simvastatin 4'-Methyl Ether; Cholestat Methyl Ether; Lipex Methyl Ether; Novo-Simvastatin Methyl Ether; Simvotin Methyl Ether. CAS No. 864357-88-0. Pack Sizes: 50 mg. Product ID: B2694-121702. Molecular formula: C26H40O5. Mole weight: 432.59. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin EP Impurity M
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: Simvastatin Ethyl Ester; Ethyl (βR,δR,1S,2S,6R,8S,8aR)-8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoate. CAS No. 864357-87-9. Pack Sizes: 10 mg. Product ID: B1370-271808. Molecular formula: C27H44O6. Mole weight: 464.63. Custom synthesis is available. Send your inquiries for more information.
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Simvastatin hydroxy acid sodium salt
A metabolite of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Group: Pharmaceutical. Alternative Names: (βR,δR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Monosodium Salt; [1S-[1α(βS*,δS*),2α,6β,8β,8aα]]-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Monosodium Salt; Simvastatin Sodium; Simvastatin Sodium Salt. CAS No. 101314-97-0. Pack Sizes: 100 mg. Product ID: B2694-479622. Molecular formula: C25H39O6. Na. Mole weight: 435.59 22.99. Custom synthesis is available. Send your inquiries for more information.
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Bergamottin
Bergamottin (5-geranoxypsoralen) is a natural furanocoumarin found in the pulp of pomelos and grapefruits. It is also found in the peel and pulp of the bergamot orange, from which it was first isolated and from which its name is derived. It shows antiproliferative activity against HepG2 liver, HL-60 leukemia, and BGC-823 gastric cancer cell lines in a dose-dependent manner and induces cell death of CHO cells following near ultraviolet irradiation. Bergamottin inhibits the cytochrome P450 isoform 3A4 with Ki of 7.7 μM and is a mixed inhibitor of simvastatin drug metabolism with Ki of 174 μM. It also increases glucose consumption in HepG2 cells in a dose-dependent manner. Group: Pharmaceutical. Alternative Names: 5-Geranoxypsoralen; Bergamottin. CAS No. 7380-40-7. Pack Sizes: 10 mg. Product ID: B2703-097781. Molecular formula: C21H22O4. Mole weight: 338.4. Custom synthesis is available. Send your inquiries for more information.
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