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| Product | Description | |
|---|---|---|
| 1,2-Distearoyl-sn-glycero-3-phospho-L-serine sodium salt | 1,2-Distearoyl-sn-glycero-3-phospho-L-serine sodium salt, an imperative lipidic component, finds application in developing liposomes deployed for efficacious drug delivery. This compound exhibits a remarkable efficacy in targeting neoplastic cells and delivering pharmacological agents directly to the site of the malignancy. Moreover, this chemical entity holds immense potential in combating neurodegenerative maladies, such as Alzheimer's. Group: Pharmaceutical. Alternative Names: 3-sn-Phosphatidyl-L-serine, distearoyl sodium salt; DSPS-Na; PS(18:0/18:0); (2S,8R)-2-Amino-5-hydroxy-11-oxo-8-[(1-oxooctadecyl)oxy]-4,6,10-trioxa-5-phosphaoctacosanoic acid 5-oxide sodium salt. CAS No. 321595-13-5. Pack Sizes: 25 mg. Product ID: B4059-188606. Molecular formula: C42H81NNaO10P. Mole weight: 814.05. Custom synthesis is available. Send your inquiries for more information. |  London |
| 2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl-Fmoc serine | 2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl-Fmoc serine is a globally recognized bioactive compound, finding its utility in the synthesis of innovative glycosylated peptides. Group: Pharmaceutical. Alternative Names: Fmoc-L-Ser(Beta-D-Glc(Ac)4)-OH; N-(9H-Fluorene-9-Ylmethoxycarbonyl)-O-(2-O,3-O,4-O,6-O-Tetraacetyl-Beta-D-Glucopyranosyl)-L-Serine. CAS No. 118358-38-6. Pack Sizes: 25 mg. Product ID: BAT-008016. Molecular formula: C32H35NO14. Mole weight: 657.63. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-galactopyranosyl-Fmoc serine | 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-galactopyranosyl-Fmoc serine, renowned as an indispensible glycosylated amino acid, is commonly utilized during the manufacture of peptides and glycopeptide antibiotics. This amino acid serves as an exemplary substrate for galactosyl transferase, a pivotal element in the aetiology of multifarious pathologies, eliciting cancer as a prominent example. Its ability to function as a progressive component adds to its significance in the realm of biomedicine and allied research. Group: Pharmaceutical. Alternative Names: N-Fmoc-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-galactopyranosyl)-L-serine; GalNAc L-serine; Fmoc-L-Ser(Alpha-D-GalNAc(Ac)3)-OH; Fmoc-Ser(GalNAc(Ac)3-Alpha-D)-OH; Fmoc-Ser(O-Alpha-D-GalNAc(OAc)3)-OH; L-Serine, N-[(9H-Fluoren-9-ylmethoxy)Carbonyl]-O-[3,4,6-Tri-O-Acetyl-2-(Acetylamino)-2-Deoxy-Alpha-D-Galactopyranosyl]-. CAS No. 120173-57-1. Pack Sizes: 25 mg. Product ID: BAT-008015. Molecular formula: C32H36N2O13. Mole weight: 656.63. Custom synthesis is available. Send your inquiries for more information. | London |
| 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl-Fmoc serine | 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl-Fmoc serine, an indispensable constituent in the realm of biomedicine, exhibits a profound impact on pharmaceutical progress, specifically in combating diverse afflictions. Its prominence extends to the creation of unprecedented antiviral and anticancer modalities, facilitation of precision drug transportation mechanisms, and exploration of intricate cellular communication routes. Group: Pharmaceutical. Alternative Names: N-α-Fmoc-O-β-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl)-L-serine; Fmoc-Ser(GlcNAc(Ac)3-β-D)-OH; Fmoc-L-Ser(beta-D-GlcNAc(Ac)3)-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(((2R,3R,4R,5S,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)propanoic acid; O-(2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosyl)-N-Fmoc-L-serine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-L-serine. CAS No. 160067-63-0. Pack Sizes: 100 mg. Product ID: BAT-015306. Molecular formula: C32H36N2O13. Mole weight: 656.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Boc-L-serine tert-butyl ester | Boc-L-serine t-butyl ester is a modified and protected amino acid used in peptide synthesis. Group: Pharmaceutical. Alternative Names: Boc-L-Ser-OtBu; Boc-L-β-hydroxyalanine tert-butyl ester; (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate. CAS No. 7738-22-9. Pack Sizes: 25 g. Product ID: BAT-002809. Molecular formula: C12H23NO5. Mole weight: 261.32. Custom synthesis is available. Send your inquiries for more information. | London |
| BOC-O-Benzyl-L-serine | 5g Pack Size. Group: Amino Acids. Formula: C15H21NO5. CAS No. 23680-31-1. Prepack ID : 66966303-5g. Molecular Weight : 295.33. |  |
| Cycloserine Impurity 1 | D-Serine is a proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. It is a inhibitor of serine palmitoyltransferase. It is also a neuromodulator. Group: Pharmaceutical. Alternative Names: D-Serine; (R)-2-Amino-3-hydroxypropanoic Acid; (R)-2-Amino-3-hydroxypropanoic Acid; (R)-Serine; NSC 77689. CAS No. 312-84-5. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008032. Molecular formula: C3H7NO3. Mole weight: 105.09. Custom synthesis is available. Send your inquiries for more information. | London |
| Cycloserine Impurity 2 | Cycloserine Impurity 2 is a derivative of Cycloserine, renowned for its remarkable efficacy in treating tuberculosand sundry bacterial afflictions. Group: Pharmaceutical. Alternative Names: D-Serine Methyl Ester Hydrochloride; (R)-2-Amino-3-hydroxypropionic Acid Methyl Ester Hydrochloride; (R)-Methyl 2-Amino-3-hydroxypropanoate Hydrochloride; Methyl D-Serinate Hydrochloride. CAS No. 5874-57-7. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008033. Molecular formula: C4H10ClNO3. Mole weight: 155.58. Custom synthesis is available. Send your inquiries for more information. | London |
| DL-Serine | 100g Pack Size. Group: Amino Acids, Biochemicals, Building Blocks, Peptide Reagents. Formula: C3H7NO3. CAS No. 302-84-1. Prepack ID : 19673855-100g. Molecular Weight : 105.09. | |
| Fmoc-L-Serine | 25g Pack Size. Group: Amino Acids. Formula: C18H17NO5. CAS No. 73724-45-5. Prepack ID : 14388650-25g. Molecular Weight : 327.33. | |
| L-Cycloserine | It is produced by the strain of Erwinia uredovora 821. L-cycloserine is an excitatory amino acid that is effective against Mycobacterium tuberculosis. It has anti-gram-negative bacterial activity. Uses: Inhibitor of ketosphinganine synthase, leading to blockade of sphingosine biosynthesis. Group: Pharmaceutical. Alternative Names: (S)-(-)-Cycloserine; (S)-Cycloserine; Cyclo-L-serine; L-4-Amino-3-isoxazolidinone; L-Cycloserine; Levcycloserine; (S)-4-Amino-3-isoxazolidinone; Levcicloserina; Levcycloserinum. CAS No. 339-72-0. Pack Sizes: 1mg;1g;10g. Product ID: BAT-008083. Molecular formula: C3H6N2O2. Mole weight: 102.09. Custom synthesis is available. Send your inquiries for more information. | London |
| L-Serine | 100g Pack Size. Group: Amino Acids, Biochemicals. Formula: C3H7NO3. CAS No. 56-45-1. Prepack ID : 24133813-100g. Molecular Weight : 105.09. | |
| L-Serine | 500kg Pack Size. Group: Amino Acids, Biochemicals. Formula: C3H7NO3. CAS No. 56-45-1. Prepack ID : 24133813-500kg. Molecular Weight : 105.09. | |
| L-Serine-[2,3,3-d3] | L-Serine-[2,3,3-d3] is a labelled L-Serine. Serine is an α-amino acid used in the biosynthesis of proteins. L-serine is a potential treatment of Amyotrophic Lateral Sclerosis (ALS). Group: Pharmaceutical. Alternative Names: (S)-2-Amino-3-hydroxypropionic Acid-d3; β-Hydroxy-L-alanine-d3; H-L-Ser-OH-d3. CAS No. 105591-10-4. Pack Sizes: 100 mg. Product ID: BLP-009349. Molecular formula: C3H4D3NO3. Mole weight: 108.11. Custom synthesis is available. Send your inquiries for more information. | London |
| L-Serine-[3,3-d2] | L-Serine-[3,3-d2] is a labelled L-Serine. Serine is an α-amino acid used in the biosynthesis of proteins. Group: Pharmaceutical. Alternative Names: L-Serine-d2. CAS No. 95034-57-4. Pack Sizes: 100 mg. Product ID: BLP-009886. Molecular formula: C3H5D2NO3. Mole weight: 107.1. Custom synthesis is available. Send your inquiries for more information. | London |
| N-α-(t-Butoxycarbonyl)-O-trityl-L-serine | Utilized extensively in the production of peptides and proteins, N-α-(t-Butoxycarbonyl)-O-trityl-L-serine is a chemical compound boasting diverse applications within the pharmaceutical arena. In addition to its fundamental use in pharmaceutical synthesis, this compound demonstrates further utility as a therapeutic agent in the treatment of cancer and autoimmune disorders. Group: Pharmaceutical. Alternative Names: Boc-Ser(Trt)-OH; (S)-2-((tert-Butoxycarbonyl)amino)-3-(trityloxy)propanoic acid. CAS No. 252897-67-9. Pack Sizes: 25 g. Product ID: BAT-003168. Molecular formula: C27H29NO5. Mole weight: 447.52. Custom synthesis is available. Send your inquiries for more information. | London |
| N-CBZ-L-Serine-OH | 25g Pack Size. Group: Amino Acids. Formula: C11H13NO5. CAS No. 1145-80-8. Prepack ID : 27070659-25g. Molecular Weight : 239.22. | |
| 1,2-Dimyristoyl-sn-glycero-3-PS sodium salt | 1,2-Dimyristoyl-sn-glycero-3-PS is an anionic phospholipid containing myristic acid (14:0) inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes. Group: Pharmaceutical. Alternative Names: 1,2-Dimyristoyl-sn-glycero-3-PS (sodium salt); 1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine; 1,2-Ditetradecanoyl-sn-glycero-phosphatidylserine; 14:0 PS; PS(14:0/14:0); DMPS. CAS No. 105405-50-3. Pack Sizes: 100 mg. Product ID: B1370-310862. Molecular formula: C34H65NNaO10P. Mole weight: 701.84. Custom synthesis is available. Send your inquiries for more information. | London |
| 2: PN: US20040072744 SEQID: 2 claimed protein | A synthetic peptide with potential for the treatment of Down's syndrome and schizophrenia. Group: Pharmaceutical. Alternative Names: PN; H-Asn-Leu-Gly-Glu-His-Pro-Val-Cys-Asp-Ser-OH; L-asparagyl-L-leucyl-glycyl-L-alpha-glutamyl-L-histidyl-L-prolyl-L-valyl-L-cysteinyl-L-alpha-aspartyl-L-serine. CAS No. 389572-87-6. Pack Sizes: 1mg;1g;10g. Product ID: BAT-010417. Molecular formula: C43H67N13O17S. Mole weight: 1070.13. Custom synthesis is available. Send your inquiries for more information. | London |
| 2:PN:US20040072744 SEQID:2 claimed protein acetate | A synthetic peptide with potential for the treatment of Down's syndrome and schizophrenia. Group: Pharmaceutical. Alternative Names: H-Asn-Leu-Gly-Glu-His-Pro-Val-Cys-Asp-Ser-OH.CH3CO2H; L-asparagyl-L-leucyl-glycyl-L-alpha-glutamyl-L-histidyl-L-prolyl-L-valyl-L-cysteinyl-L-alpha-aspartyl-L-serine acetic acid; 2: PN: US20040072744 SEQID: 2 claimed protein acetate; L-Serine, L-asparaginyl-L-leucylglycyl-L-α-glutamyl-L-histidyl-L-prolyl-L-valyl-L-cysteinyl-L-α-aspartyl-, acetate salt. CAS No. 2760881-65-8. Pack Sizes: 1mg;1g;10g. Product ID: BAT-016319. Molecular formula: C45H71N13O19S. Mole weight: 1130.2. Custom synthesis is available. Send your inquiries for more information. | London |
| A-443654 | A-443654 is a potent small-molecule inhibitor of all three Akt serine/threonine kinases, induces Akt Ser-473 phosphorylation in all human cancer cell lines tested, including PTEN- and TSC2-deficient lines. It inhibits Akt-dependent signal transduction in cells and in vivo in a dose-responsive manner. Group: Pharmaceutical. Alternative Names: A443564; A-443564; A 443564. CAS No. 552325-16-3. Pack Sizes: 1mg;1g;10g. Product ID: 552325-16-3. Molecular formula: C24H23N5O. Mole weight: 397.47. Custom synthesis is available. Send your inquiries for more information. | London |
| AA26-9 | AA26-9, synthesized based on a piperazine scaffold, is a potent and broad spectrum serine hydrolase inhibitor. Group: Pharmaceutical. Alternative Names: AA 26-9; AA-26-9; AA26-9; AA 269; AA-269; AA269; pyrrolidin-1-yl(triazol-1-yl)methanone; Pyrrolidin-1-yl(1H-1,2,3-triazol-1-yl)methanone. CAS No. 1312782-34-5. Pack Sizes: 1mg;1g;10g. Product ID: 1312782-34-5. Molecular formula: C7H10N4O. Mole weight: 166.18. Custom synthesis is available. Send your inquiries for more information. | London |
| AA38-3 | AA38-3 is a serine hydrolase (SH) inhibitor that can inhibit three SHs, ABHD6, ABHD11, and FAAH. Group: Pharmaceutical. Alternative Names: 4-Nitrophenyl piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 4-nitrophenyl ester; 4-Nitrophenyl 1-piperidinecarboxylate. CAS No. 65815-76-1. Pack Sizes: 1mg;1g;10g. Product ID: 65815-76-1. Molecular formula: C12H14N2O4. Mole weight: 250.25. Custom synthesis is available. Send your inquiries for more information. | London |
| AAF-CMK trifluoroacetate salt | AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome function, and reversibly inhibits Cln2 (TPPI). Group: Pharmaceutical. Alternative Names: N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase Inhibitor II; L-Alaninamide,L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-. CAS No. 184901-82-4. Pack Sizes: 100 mg. Product ID: BAT-015706. Molecular formula: C18H23ClF3N3O5. Mole weight: 453.84. Custom synthesis is available. Send your inquiries for more information. | London |
| AEBSF HCl | AEBSF is a water-soluble, irreversible serine protease inhibitor that inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. Group: Pharmaceutical. Alternative Names: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride; AEBSF hydrochloride; AEBSF. CAS No. 30827-99-7. Pack Sizes: 1 g. Product ID: B2693-369679. Molecular formula: C8H11ClFNO2S. Mole weight: 239.69. Custom synthesis is available. Send your inquiries for more information. | London |
| Afuresertib | Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Group: Pharmaceutical. Alternative Names: GSK-2110183; GSK 2110183; GSK2110183; GSK-2110183B; GSK 2110183B; GSK2110183B. CAS No. 1047644-62-1. Pack Sizes: 50 mg. Product ID: B1370-109132. Molecular formula: C18H17Cl2FN4OS. Mole weight: 427.32. Custom synthesis is available. Send your inquiries for more information. | London |
| Alisertib | MLN8237 is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation. Group: Pharmaceutical. Alternative Names: MLN8237; MLN-8237; MLN 8237; alisertib. Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-. CAS No. 1028486-01-2. Pack Sizes: 100 mg. Product ID: B2693-336876. Molecular formula: C27H20ClFN4O4. Mole weight: 518.9. Custom synthesis is available. Send your inquiries for more information. | London |
| AR-A014418 | AR-A014418 is an ATP-competitive inhibitor of glycogen synthase kinase 3β (GSK-3β), a serine/threonine protein kinase involved in multiple diseases including Alzheimer's disease and type 2 diabetes. Group: Pharmaceutical. Alternative Names: SN 4521; SN4521; SN-4521; AR-A 014418; AR-A014418; AR-A-014418; AR-AO-14418; GSK-3beta Inhibitor VIII; 1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea. CAS No. 487021-52-3. Pack Sizes: 25 mg. Product ID: B0084-258809. Molecular formula: C12H12N4O4S. Mole weight: 308.312. Custom synthesis is available. Send your inquiries for more information. | London |
| AT9283 | AT-9283 is a broad spectrum kinase inhibitor that potently inhibits Aurora A, Aurora B, JAK2, JAK3, and c-ABL (IC50= 3, 3, 1.2, 1.1, and 4 nM, respectively). It also potently (IC50 = <1 μM) inhibits serine/threonine kinases as well as receptor and non-receptor tyrosine kinases. Group: Pharmaceutical. Alternative Names: AT9283; AT 9283; AT-9283. CAS No. 896466-04-9. Pack Sizes: 10 mg. Product ID: B0084-100114. Molecular formula: C19H23N7O2. Mole weight: 381.43. Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-5363 | AZD-5363 is an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AZD-5363 binds to and inhibits all AKT isoforms. This agent may be used as monotherapy or combination therapy for a variety of human cancers. Group: Pharmaceutical. Alternative Names: AZD5363; AZD 5363; Capivasertib. CAS No. 1143532-39-1. Pack Sizes: 10 mg. Product ID: B2693-457058. Molecular formula: C21H25ClN6O2. Mole weight: 428.9152. Custom synthesis is available. Send your inquiries for more information. | London |
| BI-2536 | BI-2563 is a small molecule compound with potential antineoplastic activities. BI 2536 binds to and inhibits Polo-like kinase 1 (Plk1), resulting in mitotic arrest, disruption of cytokinesis, and apoptosis in susceptible tumor cell populations. Plk1, a serine/threonine-protein kinase, is a key regulator of multiple processes fundamental to mitosis and cell division. Group: Pharmaceutical. Alternative Names: BI2536; BI 2536; (R)-4-((8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide. CAS No. 755038-02-9. Pack Sizes: 50 mg. Product ID: B1370-076522. Molecular formula: C28H39N7O3. Mole weight: 521.65. Custom synthesis is available. Send your inquiries for more information. | London |
| Bortezomib USP Impurity G | Bortezomib USP Impurity G is an isomer of Bortezomib. It has been demonstrated to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer's or hypertension. Group: Pharmaceutical. Alternative Names: (1S,2S)-Bortezomib; ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. CAS No. 1132709-14-8. Pack Sizes: 10 mg. Product ID: B0103-467636. Molecular formula: C19H25BN4O4. Mole weight: 384.243. Custom synthesis is available. Send your inquiries for more information. | London |
| BX-795 | 3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, which is 140- and 1600-fold more selective than PKA and PKC. It is also a potent and relatively specific inhibitor of TBK1 with IC50 of 6 nM and IKK? with IC50 of 41 nM. Group: Pharmaceutical. Alternative Names: BX 795; BX795. CAS No. 702675-74-9. Pack Sizes: 25 mg. Product ID: B0084-194478. Molecular formula: C23H26IN7O2S. Mole weight: 591.47. Custom synthesis is available. Send your inquiries for more information. | London |
| C16 Ceramide | C16 ceramide is an endogenous ceramide, generated by ceramide synthase 6 (CerS6), that acts as a lipid second messenger to regulate apoptosis and stress signaling. It has also been found to activate NF-κB and PKCζ3. Uses: A predominant, rather hydrophobic natural ceramide. activates a cytosolic serine/threonine protein phosphatase in t9 cells; induces egf receptor phosphorylation in a-431 cells; stimulates ceramide-activated protein kinase. Group: Pharmaceutical. Alternative Names: C16 Ceramide (d18:1/16:0); N-(hexadecanoyl)-sphing-4-enine; N-Palmitoylsphingosine. CAS No. 24696-26-2. Pack Sizes: 100 mg. Product ID: B1370-059982. Molecular formula: C34H67NO3. Mole weight: 537.9. Custom synthesis is available. Send your inquiries for more information. | London |
| Calcitonin (8-32), salmon | Calcitonin (8-32), salmon is an amylin receptor antagonist with highly selectivity. Group: Pharmaceutical. Alternative Names: H-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2; L-valyl-L-leucyl-glycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-alpha-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparagyl-L-threonyl-glycyl-L-seryl-glycyl-L-threonyl-L-prolinamide; 8-32-Calcitonin (salmon reduced); Calcitonin (salmon reduced), 1-de-L-cysteine-2-de-L-serine-3-de-L-asparagine-4-de-L-leucine-5-de-L-serine-6-de-L-threonine-7-de-L-cysteine-; Salmon calcitonin (8-32). CAS No. 155069-90-2. Pack Sizes: 1mg;1g;10g. Product ID: BAT-010552. Molecular formula: C119H198N36O37. Mole weight: 2725.06. Custom synthesis is available. Send your inquiries for more information. | London |
| Camostat Mesylate | Camostat (INN) or FOY-305 is a serine protease inhibitor. Serine protease enzymes have a variety of functions in the body, and so camostat has a diverse range of uses. It is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or kidney disease orpancreatitis. Uses: Trypsin inhibitors. Group: Pharmaceutical. Alternative Names: 4-(2-(2-(dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate methanesulfonate; Camostat Mesilate; Camostat Mesylate; FOY 305; FOY-305; FOY305. CAS No. 59721-29-8. Pack Sizes: 5 g. Product ID: B2693-072632. Molecular formula: C20H22N4O5.CH4O3S. Mole weight: 494.52. Custom synthesis is available. Send your inquiries for more information. | London |
| Cobimetinib | Cobimetinib (GDC-0973, RG7420) is a potent, orally available and highly selective MEK1 inhibitor with IC50 of 4.2 nM. It shows more than 100-fold selectively for MEK1 over MEK2 when tested against a panel of more than 100 serine-threonine and tyrosine kinases and showed no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Group: Pharmaceutical. Alternative Names: XL518; GDC-0973; RG7420. CAS No. 934660-93-2. Pack Sizes: 25 mg. Product ID: B0084-460683. Molecular formula: C21H21F3IN3O2. Mole weight: 531.31. Custom synthesis is available. Send your inquiries for more information. | London |
| (Des-Gly10,D-Ser(tBu)6,Pro-NHNH29)-LHRH | (Des-Gly10,D-Ser(tBu)6,Pro-NHNH29)-LHRH is the impurity E of the Goserelin. Group: Pharmaceutical. Alternative Names: Decarbamoylgoserelin; H-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHNH2; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-L-prolinehydrazide; 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-1-9-luteinizing hormone-releasing factor (swine), hydrazide. CAS No. 147688-42-4. Pack Sizes: 1mg;1g;10g. Product ID: BAT-015276. Molecular formula: C58H83N17O13. Mole weight: 1226.39. Custom synthesis is available. Send your inquiries for more information. | London |
| (Diacetyl)-α-MSH | (Diacetyl)-α-MSH, a synthetic peptide, has been investigated extensively for its prospective applications in the management of autoimmune and inflammatory ailments, like rheumatoid arthritis and multiple sclerosis. Its anti-inflammatory properties and the ability to modulate the immune system by regulating cytokine production have been well documented. Furthermore, its efficacy as a treatment option for melanoma and obesity has been studied due to its influence on melanocortin receptors. The compound offers remarkable potential as an agent for mitigating various diseases. Group: Pharmaceutical. Alternative Names: a-Melanotropin (swine), 1-(N,O-diacetyl-L-serine)-; Ac-Ser(Ac)-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2. CAS No. 71952-90-4. Pack Sizes: 5 mg. Product ID: BAT-006209. Molecular formula: C79H111N21O20S. Mole weight: 1706.92. Custom synthesis is available. Send your inquiries for more information. | London |
| DL-threo-Droxidopa | A synthetic amino acid precursor of Norepinephrine. Antiparkinsonian. Uses: A synthetic amino acid precursor of norepinephrine. antiparkinsonian. Group: Pharmaceutical. Alternative Names: (βS)-rel-β,3-Dihydroxy-D-tyrosine; DL-threo-3-(3,4-Dihydroxyphenyl)serine; DL-DOPS; L-Threodops; DL-threo-3,4-Dihydroxyphenylserine; DL-threo-DOPS; threo-2-Amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropionic Acid; threo-β-(3,4-dihydroxyphenyl)-DL-serine. CAS No. 3916-18-5. Pack Sizes: 1mg;1g;10g. Product ID: BAT-006971. Molecular formula: C9H11NO5. Mole weight: 213.19. Custom synthesis is available. Send your inquiries for more information. | London |
| Droxidopa | Droxidopa is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). It is capable of crossing the protective blood-brain barrier. Group: Pharmaceutical. Alternative Names: (βR)-β,3-Dihydroxy-L-tyrosine; threo-β,3-Dihydroxy-L-tyrosine; L-threo-3-(3,4-Dihydroxyphenyl)serine; (-)-threo-3,4-Dihydroxyphenylserine; (2S,3R)-3-(3,4-Dihydroxyphenyl)-2-amino-3-hydroxypropanoic Acid; DOPS; L-DOPS; L-Threodops; L-threo-3,4-Dihydroxyphenylserine; L-threo-DOPS; L-threo-β-(3,4-Dihydroxyphenyl)serine; SM 5688; threo-Dopaserine. CAS No. 23651-95-8. Pack Sizes: 500 mg. Product ID: B0046-063644. Molecular formula: C9H11NO5. Mole weight: 213.19. Custom synthesis is available. Send your inquiries for more information. | London |
| D-Val-Leu-Lys 4-nitroanilide dihydrochloride | D-Val-Leu-Lys 4-nitroanilide dihydrochloride stands as a crucial substrate to gauge the efficiency of trypsin-like serine proteases. Proteolysis event leads to the release of a yellow colored product, whose quantification can be done at 405 nm. Its utility can be seen in trypsin activity detection and the evaluation of agents restricting trypsin-like proteases. Consistent usage of this product aids in experimental design and the analysis of diverse protease substrates. Group: Pharmaceutical. Alternative Names: (S)-6-Amino-2-((S)-2-((R)-2-amino-3-methylbutanamido)-4-methylpentanamido)-N-(4-nitrophenyl)hexanamide dihydrochloride; H-D-Val-Leu-Lys-pNA 2HCl. CAS No. 62354-43-2. Pack Sizes: 5 mg. Product ID: BAT-014255. Molecular formula: C23H40Cl2N6O5. Mole weight: 551.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Encorafenib | Encorafenib, also known as LGX-818, is an orally available Raf kinase inhibitor with potential antineoplastic activity. LGX818 specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells. The Raf mutation BRAF V600E is frequently upregulated in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival. Group: Pharmaceutical. Alternative Names: LGX818; LGX-818; LGX 818; Methyl N-[(2S)-1-[[4-[3-[5-chloro-2-fluoro-3-(methanesulfonamido)phenyl]-1-propan-2-ylpyrazol-4-yl]pyrimidin-2-yl]amino]propan-2-yl]carbamate. CAS No. 1269440-17-6. Pack Sizes: 150 mg. Product ID: B0084-462563. Molecular formula: C22H27ClFN7O4S. Mole weight: 540.011. Custom synthesis is available. Send your inquiries for more information. | London |
| Fmoc-Ser(tBu)-Ser(tBu)-OH | Fmoc-Ser(tBu)-Ser(tBu)-OH is a protected dipeptide used in peptide synthesis. It features an Fmoc (Fluorenylmethyloxycarbonyl) group at the N-terminus, which protects the amino group during synthesis. Each Ser (Serine) residue is protected by a tBu (tert-butyl) group at the hydroxyl side chain, preventing unwanted side reactions. The -OH at the C-terminus indicates a free carboxyl group, allowing the dipeptide to be coupled with other amino acids. This compound is used to incorporate serine residues into peptides while maintaining the integrity of the hydroxyl groups for selective deprotection later in the synthesis process. Group: Pharmaceutical. Alternative Names: N-(Fluorenylmethoxycarbonyl)-O-tert-butyl-L-seryl-O-tert-butyl-L-serine; (S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(tert-butoxy)propanamido)-3-(tert-butoxy)propanoic acid; L-Serine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-seryl-O-(1,1-dimethylethyl)-; L-Serine, O-(1,1-dimethylethyl)-N-[O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-seryl]-; N-(N-. CAS No. 110098-50-5. Pack Sizes: 100 mg. Product ID: BAT-002488. Molecular formula: C29H38N2O7. Mole weight: 526.62. Custom synthesis is available. Send your inquiries for more information. | London |
| GRGDS | GRGDS is a synthetic integrin antagonist. Group: Pharmaceutical. Alternative Names: GRGDS; GRGDS 1/2ACOH 2H2O; GRGDS, FIBRONECTIN ATTACHMENT PEPTIDE; GLY-ARG-GLY-ASP-SER; GLY-ARG-GLY-ASP-SER 1/2ACOH 2H2O; H-GLY-ARG-GLY-ASP-SER-OH; glycyl-arginyl-glycyl-aspartyl-serine; GLY-ARG-GLY-ASP-SER ACETATE. CAS No. 96426-21-0. Pack Sizes: 50 mg. Product ID: BAT-010197. Molecular formula: C17H30N8O9. Mole weight: 490.5. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-1070916A | GSK-1070916A is an ATP-competitive inhibitor of the serine/threonine kinases Aurora B and C with potential antineoplastic activity. Aurora B/C kinase inhibitor GSK1070916A binds to and inhibits the activity of Aurora kinases B and C, which may result in inhibition of cellular division and a decrease in the proliferation of tumor cells that overexpress the Aurora kinases B and C. Aurora kinases play essential roles in mitotic checkpoint control during mitosis, and are overexpressed by a wide variety of cancer cell types. Group: Pharmaceutical. Alternative Names: GSK 1070916; GSK-1070916; GSK 1070916; GSK1070916A; GSK 1070916A; NMI-900; NMI 900; NMI900; N'-[4-[4-[2-[3-[(Dimethylamino)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]-1-ethyl-1H-pyrazol-3-yl]phenyl]-N,N-dimethylurea. CAS No. 942918-07-2. Pack Sizes: 25 mg. Product ID: B1370-100932. Molecular formula: C30H33N7O. Mole weight: 507.63. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK-461364 | GSK-461364 is a Polo-like kinase 1 inhibitor, is also a small molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor GSK461364 selectively inhibits Plk1, inducing selective G2/M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. Plk1, named after the polo gene of Drosophila melanogaster, is a serine/threonine protein kinase involved in regulating mitotic spindle function in a non-ATP competitive manner. Group: Pharmaceutical. Alternative Names: GSK461364; GSK 461364; GSK-461364; GSK461364A; GSK 461364A; GSK-461364A. 5-[6-[(4-Methyl-1-piperazinyl)methyl]-1h-benzimidazol-1-yl]-3-[(1r)-1-[2-(trifluoromethyl)phenyl]ethoxy]-2-thiophenecarboxamide. CAS No. 929095-18-1. Pack Sizes: 10 mg. Product ID: B0084-307746. Molecular formula: C27H28F3N5O2S. Mole weight: 543.609. Custom synthesis is available. Send your inquiries for more information. | London |
| GSK583 | GSK583 is a selective receptor-interacting serine/threonine-protein kinase 2 (RIP2 Kinase) inhibitor and the RIP2K binding IC50 is 5 nM. GSK583 can inhibit both TNF-α and IL-6 production with an IC50 value of 200 nM in an ex vivo human translational model. Group: Pharmaceutical. Alternative Names: GSK583; GSK 583; GSK-583. 6 - (tert-Butylsulfonyl) - N - (5-fluoro - 1H - indazol-3-yl)quinolin-4-amine. CAS No. 1346547-00-9. Pack Sizes: 25 mg. Product ID: B0084-475334. Molecular formula: C20H19FN4O2S. Mole weight: 398.46. Custom synthesis is available. Send your inquiries for more information. | London |
| HMN-214 | HMN-214 is an oral prodrug of HMN-176, a stilbene derivative that interferes with the subcellular spatial location of polo-like kinase-1, a serine/threonine kinase that regulates critical mitotic events. Group: Pharmaceutical. Alternative Names: HMN-214; HMN 214. CAS No. 173529-46-9. Pack Sizes: 50 mg. Product ID: B2693-321779. Molecular formula: C22H20N2O5S. Mole weight: 424.471. Custom synthesis is available. Send your inquiries for more information. | London |
| Ipatasertib | Ipatasertib, also known as GDC-0068 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Uses: Antineoplastic agents. Group: Pharmaceutical. Alternative Names: GDC-0068; GDC0068; GDC 0068; RG7440; RG-7440; RG 7440; Ipatasertib. CAS No. 1001264-89-6. Pack Sizes: 50 mg. Product ID: B2693-456282. Molecular formula: C24H32ClN5O2. Mole weight: 458. Custom synthesis is available. Send your inquiries for more information. | London |
| Isopropyl ethanesulfonate | Propan-2-yl Ethane-1-sulfonate can be used as serine protease inhibitors to inhibit an increase in the blood gluocose level. Group: Pharmaceutical. Alternative Names: Ethanesulfonic acid isopropyl ester; Ethanesulfonic acid, isopropyl ester. CAS No. 14245-62-6. Pack Sizes: 1 g. Product ID: B2699-301730. Molecular formula: C5H12O3S. Mole weight: 152.21. Custom synthesis is available. Send your inquiries for more information. | London |
| Kallikrein Inhibitor | Kallikrein Inhibitor, a synthetic peptide, is a serine protease inhibitor that inhibits kallikrein and plasmin, and can attenuate breast cancer cell invasion. Group: Pharmaceutical. Alternative Names: KKI 5; KKI-5; KKI5; Ac-Pro-phe-arg-ser-val-gln-NH2; (S)-2-((3S,6S,9S,12S)-1-((S)-1-acetylpyrrolidin-2-yl)-3-benzyl-6-(3-guanidinopropyl)-9-(hydroxymethyl)-12-isopropyl-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecan-13-amido)pentanediamide; N-acetyl-L-prolyl-L-phenylalanyl-L-arginyl-L-seryl-L-valyl-L-glutaminamide. CAS No. 97145-43-2. Pack Sizes: 10 mg. Product ID: BAT-006188. Molecular formula: C35H55N11O9. Mole weight: 773.88. Custom synthesis is available. Send your inquiries for more information. | London |
| Leupeptin hemisulfate | Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases. It can be used in skincare products to help reduce inflammation and provide soothing effects to the skin. Group: Pharmaceutical. Alternative Names: Ac-Leu-Leu-Arg-CHO.1/2H2SO4; Acetyl Tripeptide; L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1); L-Leucinamide, N-acetyl-L-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-, (S)-, sulfate (2:1); Leupeptin sulfate (2:1); N-Acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-L-leucinamide hemisulfate; Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate; N-Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate; Ac-Leu-Leu-Arg-al.1/2H2SO4; Ac-LLR-al.1/2H2SO4. CAS No. 103476-89-7. Pack Sizes: 300 mg. Product ID: BAT-010325. Molecular formula: C20H38N6O4.1/2H2SO4. Mole weight: 475.59. Custom synthesis is available. Send your inquiries for more information. | London |
| Linifanib | Description of Linifanib: Linifanib is an orally bioavailable, small-molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Linifanib inhibits members of the vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) receptor families; it exhibits much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. This agent does not have a general antiproliferative effect due to its high dose requirement. However, linifanib may exhibit potent antiproliferative and apoptotic effects on tumor cells whose proliferation is dependent on mutant kinases, such as fms-related tyrosine kinase receptor-3 (FLT3). Group: Pharmaceutical. Alternative Names: ABT869; ABT 869; ABT-869; Linifanib. CAS No. 796967-16-3. Pack Sizes: 200 mg. Product ID: B0084-151820. Molecular formula: C21H18FN5O. Mole weight: 375.407. Custom synthesis is available. Send your inquiries for more information. | London |
| LL-37, Human | LL-37 is a cationic and α-helical antimicrobial peptide. It can inhibit growth of Gram-positive E. coli D21 and Gram-negative B. megatarium in a concentration-dependent manner. LL-37 can promote wound healing following skin-targeted electroporation of a plasmid encoding hCAP-18/LL-37 in mice. Group: Pharmaceutical. Alternative Names: LL 37; LL37; L-leucyl-L-leucyl-glycyl-L-alpha-aspartyl-L-phenylalanyl-L-phenylalanyl-L-arginyl-L-lysyl-L-seryl-L-lysyl-L-alpha-glutamyl-L-lysyl-L-isoleucyl-glycyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-alpha-aspartyl-L-phenylalanyl-L-leucyl-L-arginyl-L-asparagyl-L-leucyl-L-valyl-L-prolyl-L-arginyl-L-threonyl-L-alpha-glutamyl-L-serine; H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH; Cathelicidin; Bac4; Cap-18. CAS No. 154947-66-7. Pack Sizes: 1 mg. Product ID: BAT-006133. Molecular formula: C205H340N60O53. Mole weight: 4493.25. Custom synthesis is available. Send your inquiries for more information. | London |
| Mesupron | Mesupron is the second generation serine protease inhibitor prodrug targeting the human urokinase plasminogen activator (uPA) system with potential antineoplastic and antimetastatic activities. Group: Pharmaceutical. Alternative Names: 1-Piperazinecarboxylic acid, 4-[(2S)-3-[3-[(hydroxyamino)iminomethyl]phenyl]-1-oxo-2-[[[2,4,6-tris(1-methylethyl)phenyl]sulfonyl]amino]propyl]-, ethyl ester; Ethyl 4-[(2S)-3-[3-[(hydroxyamino)iminomethyl]phenyl]-1-oxo-2-[[[2,4,6-tris(1-methylethyl)phenyl]sulfonyl]amino]propyl]-1-piperazinecarboxylate; (S)-Ethyl 4-(3-(3-(N-hydroxycarbamimidoyl)phenyl)-2-(2,4,6-triisopropylphenylsulfonamido)propanoyl)piperazine-1-carboxylate; WX 671; WX671; WX-671. CAS No. 590368-25-5. Pack Sizes: 5 mg. Product ID: B0084-462232. Molecular formula: C32H47N5O6S. Mole weight: 629.82. Custom synthesis is available. Send your inquiries for more information. | London |
| Milciclib | Milciclib is an orally bioavailable inhibitor of cyclin-dependent kinases (CDKs) and thropomyosin receptor kinase A (TRKA), with potential antineoplastic activity. CDK2/TRKA inhibitor PHA-848125 AC potently inhibits cyclin-dependent kinase 2 (CDK2) and exhibits activity against other CDKs including CDK1 and CDK4, in addition to TRKA. Inhibition of these kinases may result in cell cycle arrest and apoptosis of tumor cells that express these kinases. CDKs are serine/threonine kinases involved in regulation of the cell cycle and may be overexpressed in some cancer cell types. The neurotrophin receptor TRKA is mutated in a variety of cancer cell types. Group: Pharmaceutical. Alternative Names: PHA-848125; PHA848125; PHA 848125; PHA-848125AC; PHA 848125AC; PHA848125AC. CAS No. 802539-81-7. Pack Sizes: 5 mg. Product ID: B0084-459709. Molecular formula: C25H32N8O. Mole weight: 460.57. Custom synthesis is available. Send your inquiries for more information. | London |
| Nafamostat mesilate | Nafamostat Mesylate is a synthetic serine protease inhibitor and an anticoagulant. It is a fast-acting proteolytic inhibitor and used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. Alternative Names: 6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate; Nafamostat mesylate; nafamostat mesilate; FUT-175; FUT 175; FUT175. CAS No. 82956-11-4. Pack Sizes: 5 g. Product ID: BAT-008979. Molecular formula: C21H25N5O8S2. Mole weight: 539.58. Custom synthesis is available. Send your inquiries for more information. | London |
| NCT-503 | NCT-503 is a non-competitive phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50= 2.5 μM), reducing the production of glucose-derived serine in cells and suppressing the growth of PHGDH-dependent cancer cells in culture and in orthotopic xenograft tumors. Group: Pharmaceutical. Alternative Names: NCT-503; NCT 503; NCT503. N-(4,6-dimethylpyridin-2-yl)-4-[[4-(trifluoromethyl)phenyl]methyl]piperazine-1-carbothioamide. CAS No. 1916571-90-8. Pack Sizes: 100 mg. Product ID: B1370-007403. Molecular formula: C20H23F3N4S. Mole weight: 408.48. Custom synthesis is available. Send your inquiries for more information. | London |
| N-Desmethyl Enzalutamide | N-desmethyl Enzalutamide is a major metabolite of Enzalutamide. Enzalutamide is an androgen-receptor (AR) antagonist (IC50 = 36 nM) in LNCaP cells that inhibits the transcriptional activity of a mutant AR protein. Enzalutamide resists against induction of prostate-specific antigen (PSA) and transmembrane serine protease 2 (TMPRSS2). N-desmethyl Enzalutamide can be used for the treatment of disorders involving androgen, estrogen and progesterone receptors. Uses: The treatment of disorders involving androgen, estrogen and progesterone receptors. Group: Pharmaceutical. Alternative Names: N-desmethylenzalutamide; 1242137-16-1; 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzamide; 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluorobenzamide; Enzalutamide metabolite. CAS No. 1242137-16-1. Pack Sizes: 20 mg. Product ID: B0084-474425. Molecular formula: C20H14F4N4O2S. Mole weight: 450.412. Custom synthesis is available. Send your inquiries for more information. | London |
| NMS-1286937 | NMS1286937, also know as NMS-P937, is an orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor NMS-1286937 selectively inhibits PLK1, inducing selective G2/M cell-cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell-cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1 inhibition may result in the inhibition of proliferation in PLK1-overexpressing tumor cells. PLK1 is a serine/threonine protein kinase crucial in the regulation of mitosis. Uses: Protein kinase inhibitors. Group: Pharmaceutical. Alternative Names: PCM-075; PCM 075; PCM075; NMS1286937; NMS 1286937; NMS-1286937; NMS-P937; NMS-P-937; NMS-P 937; Onvansertib. CAS No. 1034616-18-6. Pack Sizes: 500 mg. Product ID: B1370-462742. Molecular formula: C24H27F3N8O3. Mole weight: 532.53. Custom synthesis is available. Send your inquiries for more information. | London |
| N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt | N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt is a chromogenic substrate for plasmin determination, serine protease activity and fibrinogen decomposition determination. Group: Pharmaceutical. Alternative Names: N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt; Tos-GPK-pNA; Tos-Gly-Pro-Lys-pNA acetate; N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide, monoacetate. CAS No. 88793-79-7. Pack Sizes: 50 mg. Product ID: BAT-010163. Molecular formula: C28H38N6O9S. Mole weight: 634.7. Custom synthesis is available. Send your inquiries for more information. | London |
| Palmitoyl pentapeptide-4 hydrochloride | Palmitoyl pentapeptide-4 is a matrikine messenger peptide that can effectively promote the production of collagen, hyaluronic acid and elastic fibers in the skin, increase skin water content and moisture retention, increase skin thickness, enhance skin firmness and gloss, and eliminate static lines. Palmitoyl pentapeptide-4 addresses the skin condition at its source, rebuilding it from the inside out to reverse the skin aging process. Palmitoyl pentapeptide-4 exhibits anti-wrinkle activity and is used in cosmetics. Group: Pharmaceutical. Alternative Names: N2-(1-Oxohexadecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-serine hydrochloride; Matrixyl hydrochloride; Palmitoyl-KTTKS hydrochloride; Palmitoyl Pentapeptide hydrochloride; PAL-KTTKS hydrochloride. Pack Sizes: 1 g. Product ID: BAT-010788. Molecular formula: C39H76ClN7O10. Mole weight: 838.53. Custom synthesis is available. Send your inquiries for more information. | London |
| PF-04691502 | PF-04691502 is an agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the PI3K/mTOR signaling pathway, with potential antineoplastic activity. It inhibits both PI3K and mTOR kinases, which may result in apoptosis and growth inhibition of cancer cells overexpressing PI3K/mTOR. Activation of the PI3K/mTOR pathway promotes cell growth, survival, and resistance to chemotherapy and radiotherapy. mTOR, a serine/threonine kinase downstream of PI3K, may also be activated independent of PI3K. Group: Pharmaceutical. Alternative Names: PF04691502; PF 04691502; PF-04691502; PF4691502; PF 4691502; PF-4691502; 2-amino-8-((1R,4R)-4-(2-hydroxyethoxy)cyclohexyl)-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 1013101-36-4. Pack Sizes: 50 mg. Product ID: B0084-456382. Molecular formula: C22H27N5O4. Mole weight: 425.489. Custom synthesis is available. Send your inquiries for more information. | London |
| PF-06650833 | PF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), which is an omnipresently expressed serine/threonine kinase involved in the regulation of innate immunity. PF-06650833 is useful for the treatment of autoimmune and inflammatory diseases associated with lnterleukin-1 Receptor Associated Kinase (IRAK) and more particularly modulates the function of IRAK. It is undergoing testing in a Phase II clinical study. Group: Pharmaceutical. Alternative Names: zimlovisertib; PF 06650833; PF06650833. CAS No. 1817626-54-2. Pack Sizes: 25 mg. Product ID: B0084-474124. Molecular formula: C18H20FN3O4. Mole weight: 361.373. Custom synthesis is available. Send your inquiries for more information. | London |
| POPS-Na | POPS-Na is a negatively charged membrane lipid. It is also a reagent that triggered the release of 5-Aminolevulinic acid (5-ALA) from stealth liposomes. Group: Pharmaceutical. Alternative Names: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); POPS(16:0/18:1(9Z)); 16:0-18:1 PS (POPS) (sodium salt). CAS No. 321863-21-2. Pack Sizes: 100 mg. Product ID: B1370-188610. Molecular formula: C40H75NNaO10P. Mole weight: 784. Custom synthesis is available. Send your inquiries for more information. | London |
| Proteinase K | Proteinase K is a subtilisin-related serine protease. It was discovered from the fungus Engyodontium album. It can be used for removal of endogenous nucleases during the preparation of DNA and RNA, and for preparation of tissue sections for in situ hybridization. It is often used in pH range 7.5-9.0 and 37-70°C. Specific activity is ≥ 34 units/mg of protein. Group: Pharmaceutical. Alternative Names: EC 3.4.21.64; endopeptidase K; Tritirachium alkaline proteinase; Tritirachium album serine proteinase; Tritirachium album proteinase K. CAS No. 39450-01-6. Pack Sizes: 1 g. Product ID: BBF-04168. Custom synthesis is available. Send your inquiries for more information. | London |
| Regorafenib | Regorafenib, also known as BAY 73-4506, is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. VEGFRs are receptor tyrosine kinases that play important roles in tumor angiogenesis; the receptor tyrosine kinases RET, KIT, and PDGFR, and the serine/threonine-specific Raf kinase are involved in tumor cell signaling. Regorafenib is demonstrated to increase the overall survival of patients with metastatic colorectal cancer and has been approved by the US FDA on September 27, 2012. Uses: Antineoplastic agent. Group: Pharmaceutical. Alternative Names: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; Regorafenibum; Stivarga; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY 73-4506; BAY 734506; BAY734506; BAY-734506. CAS No. 755037-03-7. Pack Sizes: 500 mg. Product ID: BBF-05856. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.83. Custom synthesis is available. Send your inquiries for more information. | London |
| RGB-286638 Free base | RGB-286638 is a novel CDK inhibitor. It inhibited several tyrosine and serine/threonine non-CDK enzymes, i.e. GSK-3β, TAK1, AMPK, Jak2, MEK1. It demonstrated equimolar (50nM) activity in freshly isolated tumor cells from MM patients, while manifesting less cytotoxicity in healthy donor PBMCs. It reduced the phosphorylation of Rb at S807/811 in MM.1S and MM.1R cells, but had no effects on p-Rb S780. Group: Pharmaceutical. Alternative Names: 1-[3-[4-[[4-(2-methoxyethyl)piperazin-1-yl]methyl]phenyl]-4-oxo-1H-indeno[1,2-c]pyrazol-5-yl]-3-morpholin-4-ylurea; RGB 286638; RGB286638. CAS No. 784210-88-4. Pack Sizes: 100 mg. Product ID: B0084-463330. Molecular formula: C29H35N7O4. Mole weight: 545.63. Custom synthesis is available. Send your inquiries for more information. | London |
| Rigosertib sodium | Rigosertib (ON-01910 sodium salt), a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity, is a non-ATP-competitive inhibitor of PLK1 (IC50=9 nM), inducing selective G2/M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. This agent may exhibit synergistic antitumor activity in combination with other chemotherapeutic agents. Plk1, named after the polo gene of Drosophila melanogaster, is a serine/threonine protein kinase involved in regulating mitotic spindle function in a non-ATP competitive manner. Group: Pharmaceutical. Alternative Names: Glycine, N-[2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]phenyl]-, monosodium salt (9CI); (E)-2,4,6-Trimethoxystyryl 3-[(carboxymethyl)amino]-4-methoxybenzyl sulfone sodium salt; Novonex; ON 01910 sodium; ON01910 sodium; ON-01910 sodium; ON 01910 sodium salt; Rigosertib sodium. CAS No. 1225497-78-8. Pack Sizes: 50 mg. Product ID: B0084-286621. Molecular formula: C21H24NNaO8S. Mole weight: 473.47. Custom synthesis is available. Send your inquiries for more information. | London |
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