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| Product | Description | |
|---|---|---|
| Sephin 1 | Sephin 1 is a selective PPP1R15A inhibitor devoid of PPP1R15B and α2-adrenergic activity. In cells, Sephin 1 selectively disrupted the PPP1R15A-PP1c complex, thus prolonging eIF2α phosphorylation after stress, delaying translation recovery, and attenuated expression of stress genes such as the pro-apoptotic protein CHOP. In mice, Sephin 1 safely prevented the motor, morphological, and molecular defects of two otherwise unrelated protein-misfolding diseases. Uses: Potential treatment of protein misfolding disease. Group: Pharmaceutical. Alternative Names: Sephin1; Sephin-1. CAS No. 951441-04-6. Pack Sizes: 250 mg. Product ID: B1370-055259. Molecular formula: C8H9ClN4. Mole weight: 196.64. Custom synthesis is available. Send your inquiries for more information. |  London |
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