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| Product | Description | |
|---|---|---|
| Chlorin E6 | Chlorin E6 is a naturally occurring photosensitizer that can be used as a photodynamic therapy (PDT) drug candidate. Uses: Radiation-sensitizing agents. Group: Pharmaceutical. CAS No. 19660-77-6. Pack Sizes: 250 mg. Product ID: B2703-396047. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Levosimendan | Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC). Uses: Vasodilator agents. Group: Pharmaceutical. CAS No. 141505-33-1. Pack Sizes: 1 g. Product ID: B2693-058487. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Metronidazole | Metronidazole is a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class. It is a limited spectrum antibiotic that has activity against anaerobic gram-positive and anaerobic gram-negative bacteria. It is also promisingly to be a radiation sensitizer for hypoxic cells. Group: Pharmaceutical. CAS No. 443-48-1. Pack Sizes: 500 g. Product ID: BBF-04552. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MSDC-0602 | MSDC-0602 is an insulin sensitizer that has the potential to treat diabetes and other inflammatory diseases. It exhibits low affinity for binding and activation of PPAR&gamma. Group: Pharmaceutical. CAS No. 1133819-87-0. Pack Sizes: 50 mg. Product ID: B0084-284775. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pimobendan | Pimobendan is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Uses: Phosphodiesterase inhibitors. Group: Pharmaceutical. CAS No. 74150-27-9. Pack Sizes: 2 g. Product ID: B0084-303517. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 10-Acetyl-3,7-dihydroxyphenoxazine | 10-Acetyl-3,7-dihydroxyphenoxazine is a sensitive and stable substrate for horseradish peroxidase (HRP). It reacts with H2O2 to produce the fluorescent compound resorufin that can be used for detection of H2O2. Group: Pharmaceutical. CAS No. 119171-73-2. Pack Sizes: 1 g. Product ID: B0001-161736. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-Methyl-4-piperidone-[2,2,6,6-d4] | 1-Methyl-4-piperidone-[2,2,6,6-d4], a deuterium-labeled analog of the potent neurotransmitter acetylcholine, has been extensively employed to scrutinize the intricate metabolic pathways of acetylcholine. Owing to its properties, it has garnered immense interest in the pharmaceutical and agrochemical sectors, rendering it a vital precursor in various chemical syntheses. The intricate isotopic labeling of this compound confers significant benefits in terms of stability, efficiency, and sensitivity in investigative studies. Group: Pharmaceutical. CAS No. 1189723-14-5. Pack Sizes: 10 mg. Product ID: BLP-009661. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 1-NA-PP1 | 1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. Group: Pharmaceutical. CAS No. 221243-82-9. Pack Sizes: 25 mg. Product ID: B2693-102805. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2,2-dimethyldodecanoic Acid | 2,2-Dimethyldodecanoic acid, an intriguing biochemical, has emerged as a promising therapeutic candidate for the treatment of neurological disorders and diabetes. As a modulator of the mitochondrial membrane, this compound has garnered attention for its ability to enhance insulin sensitivity and glucose tolerance in experimental subjects, showcasing its therapeutic potential in metabolic disorders. Furthermore, preclinical investigations have yielded encouraging results, highlighting its potential to serve as a potent anxiolytic and antidepressant agent, rendering it a prime target for future research. Group: Pharmaceutical. CAS No. 2874-73-9. Pack Sizes: 10 g. Product ID: B1370-204330. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Butylresorcinol | 4-Butylresorcinol has an inhibitory effect on melanin production by directly inhibiting tyrosinase activity, as well as inhibiting tyrosinase synthesis in B16 melanoma cells without causing any cytotoxicity. It is an excellent antioxidant with good stability and safety, without potential irritants and sensitivities. Group: Pharmaceutical. CAS No. 18979-61-8. Pack Sizes: 50 g. Product ID: B1370-341086. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 4-Hydroxyisoleucine | 4-Hydroxyisoleucine, which comes from the seeds of Trigonella foenum-graecum L, could inhibit palmitate-induced, ROS-associated inflammation and restored insulin sensitivity through regulating IRS-1 function. It acts to improve insulin resistance by promoting mitochondrial biogenesis in high fructose diet fed STZ induced diabetic rats. Besides, 4-Hydroxyisoleucine could remarkably improve high glucose-induced IR in 3T3-L1 adipocytes. Meanwhile, 4-HIL could inhibit the secretion of TNF-alpha. Group: Pharmaceutical. CAS No. 781658-23-9. Pack Sizes: 100 mg. Product ID: B0005-347850. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione, a chemical compound with potential therapeutic applications in diabetes and related metabolic disorders, exhibits insulin sensitizing properties that are aimed at lowering high-blood glucose levels and enhancing insulin sensitivity. Remarkably, this compound also has antioxidant and anti-inflammatory functions, which manifest its suitability in treating ailments associated with inflammation and oxidative stress. Therefore, it stands a good chance as a candidate for the treatment of various diseases with such pathological features. Group: Pharmaceutical. CAS No. 6325-94-6. Pack Sizes: 50 mg. Product ID: B0001-284762. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(3,4-Dimethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | 5-[(3,4-Dimethoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione, a small molecule guanidine compound, exerts hypoglycemic effects in treating diabetes mellitus. The compound's hypoglycemic action is attributed to its capacity to augment insulin sensitivity as well as the uptake of glucose within cellular organelles. Group: Pharmaceutical. CAS No. 6325-95-7. Pack Sizes: 50 mg. Product ID: B0001-284770. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione | The compound 5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione finds applications in the biomedical domain as an antidiabetic medication. Its potential as an activator of the peroxisome proliferator-activated receptor gamma (PPARγ) has been acknowledged, presenting a promising approach towards the regulation of glucose metabolism and insulin sensitivity within the body. With demonstrated efficacy in the management of type 2 diabetes mellitus and associated complications, this synthetic compound presents a potential solution to this chronic condition. Group: Pharmaceutical. CAS No. 24044-50-6. Pack Sizes: 50 mg. Product ID: B0001-284767. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 5-Chloro-2'-deoxyuridine | It is an anticancer agent and a radio-sensitizing agent for cancer treatment. Group: Pharmaceutical. CAS No. 50-90-8. Pack Sizes: 1 g. Product ID: B1370-179178. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| A 39183A | It is an anthraquinone antibiotic produced by the strain of streptomyces sp. It has broad spectrum antimicrobial activity against both sensitive and resistant strains, including many anaerobic bacteria. It also has the activity against gram-positive and gram-negative bacteria. Group: Pharmaceutical. CAS No. 79426-51-0. Pack Sizes: 1mg; 1g; 10g. Product ID: BBF-04211. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl Hexapeptide-49 acetate | Acetyl Hexapeptide-49 acetate is a photoprotectic cosmetic peptide that diminishes Proteinase-Activated Receptor 2 (PAR-2)-induced release of pro-inflammatory mediators, attenuating neurogenic inflammation and itch response in sensitive skin (Lipotec, Barcelona, Spain). Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-016153. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acetyl tetrapeptide-15 | Acetyl tetrapeptide-15 is an anti-inflammatory ingredient in cosmetics used for neurosensitive skin. Acetyl tetrapeptide-15 is a polypeptide that increases the skin's natural tolerance threshold. It has anti-allergenic, anti-inflammatory, and anti-irritant properties, reduces the skin's response to irritants, and is especially helpful for highly sensitive and allergic skin. Group: Pharmaceutical. CAS No. 928007-64-1. Pack Sizes: 10 mg. Product ID: BAT-006221. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 | Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 is a sensitive fluorescent (FRET) peptide substrate for cathepsin D. This enzyme degrades extracellular matrix components and may promote the spread of tumor cells. High levels of active cathepsin D were found in senile plaques in the brains of Alzheimer's patients. Group: Pharmaceutical. CAS No. 400716-78-1. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014426. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt | It is used as a substrate in a rapid, sensitive, continuous spectrophotometric assay for vertebrate collagenase, gelatinase A, and gelatinase B. Group: Pharmaceutical. CAS No. 98992-65-5. Pack Sizes: 1mg; 1g; 10g. Product ID: BAT-014952. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Acridine Phosphoramidite | Acridine Phosphoramidite is a specialized reagent used in oligonucleotide synthesis to introduce acridine moieties into the oligonucleotide sequence. Acridine derivatives are known for their unique fluorescence properties, making them valuable for applications such as nucleic acid labeling, detection, and imaging. By incorporating acridine moieties into oligonucleotides, researchers can develop probes and molecular tools for studying DNA/RNA structure, dynamics, and interactions. This modification enables sensitive detection and visualization of nucleic acids in various biological assays and techniques, including fluorescence microscopy, in situ hybridization, and nucleic acid-based sensors. Group: Pharmaceutical. CAS No. 402829-33-8. Pack Sizes: 1mg; 1g; 10g. Product ID: BRP-00543. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ac-Tyr-Arg-cetyl ester | Ac-Tyr-Arg-cetyl ester is an ingredient in anti-wrinkle cosmetics. It can inhibit the production of calcitonin gene-related peptide (CGRP), produce β-endorphins, and raise the threshold of skin sensitivity to heat. Group: Pharmaceutical. CAS No. 196604-48-5. Pack Sizes: 5 mg. Product ID: BAT-006228. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Apigenin | Apigenin is the main active ingredient of Chamomil Extract. Chamomile is rich in flavonoid active ingredients and has antioxidant, anti-angiogenic, anti-inflammatory, anti-allergic and anti-viral effects. The active ingredients of chamomile can be applied to high-end anti-sensitive skin care products through issofree technology. It has a good soothing effect on itchy skin, it gently replenishes water and soothes the skin. Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM. Apigenin is a good functional cosmetics material. Group: Pharmaceutical. CAS No. 520-36-5. Pack Sizes: 500 mg. Product ID: NP2545. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZD-9291 | AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. AZD9291 is highly active in preclinical models and is well tolerated in animal models. AZD 9291 is an irreversible inhibitor of epidermal growth factor receptor (EGFR) sensitizing and T790M resistance mutations (IC50s = 15-17 nM) while sparing the wild-type form of the receptor (IC50 = 480 nM). It binds the related IGF1R and hERG receptors with significantly reduced potency (IC50s = 2.9 and 16.2 μM, respectively). Uses: For research used only. Group: Pharmaceutical. CAS No. 1421373-65-0. Pack Sizes: 2.5 g. Product ID: B0084-462147. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Azoramide | Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It is a dual-function endoplasmic reticulum (ER) modulator in vitro. It improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones to protect cells against ER stress in multiple systems. It regulates ER folding and secretion capacity without inducing ER stress. It might have the protective effects of enhancing chaperone expression and reducing protein synthesis without inducing cytotoxicity and apoptosis. It showed potent antidiabetic activity in two independent mouse models of obesity by protecting pancreatic β cell function against ER stress and improving insulin sensitivity in vivo. It improves glucose homeostasis in mice with genetic obesity and diet-induced obesity. Group: Pharmaceutical. CAS No. 932986-18-0. Pack Sizes: 100 mg. Product ID: B1370-474920. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bavachinin | Bavachinin is a natural compound isolated from the Chinese herb Fructus Psoraleae. Bavachinin has potent anti-angiogenic activity in vitro and in vivo. Bavachinin inhibited increases in HIF-1α activity in human KB carcinoma (HeLa cell derivative) and human HOS osteosarcoma cells under hypoxia in a concentration-dependent manner, probably by enhancing the interaction between von Hippel-Lindau (VHL) and HIF-1&alpha. It significantly inhibited Th2 cytokine production, including IL-4, IL-5 and IL-13. Notably, this compound almost completely blocked inflammation in the ovalbumin (OVA)-sensitized animal asthma model. Uses: Antiinflammatory; antipyretic; analgesic. Group: Pharmaceutical. CAS No. 19879-30-2. Pack Sizes: 100 mg. Product ID: NP1951. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Bedaquiline | TMC207 is a first-in-class diarylquinoline compound with a novel mechanism of action, the inhibition of bacterial ATP synthase, and potent activity against drug-sensitive and drug-resistant TB. Group: Pharmaceutical. CAS No. 843663-66-1. Pack Sizes: 100 mg. Product ID: B0084-152490. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| β-Nicotinamide Mononucleotide | β-Nicotinamide mononucleotide, a major product of extracellular NAMPT reaction, could ameliorate glucose intolerance and also increase hepatic insulin sensitivity and sorts of gene expression involved in inflammatory response, oxidative stress and so on. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 1094-61-7. Pack Sizes: 5 g. Product ID: B0084-245647. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BKM120 | BKM120, also called as buparlisib or NVP-BKM120, activity in a range of preclinical cancer models, specifically inhibits class I PI3K isoforms, which blocks p110α (IC50 = 52 nM), p110β (IC50 = 166 nM), p110δ (IC50 = 116 nM) and p110γ (IC50 = 262 nM). BKM120 displays little sensitive to Class III and Class IV PI3K's or PI4K. Group: Pharmaceutical. CAS No. 944396-07-0. Pack Sizes: 200 mg. Product ID: B0084-438224. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| BR-3042 | Aromatic polyether urethane diacrylate; results in soft. highly elongative, tacky systems ideal for use in UV. pressure sensitive adhesives (PSA), or UV-curable. laminating adhesives; enhances adhesion and improves. solvent resistance. Uses: Coatings, adhesives. Group: Oligomer. Oligomer Functionality: 2. Viscosity [CP]: 7,700 (Neat). Durometer Hardness: 23A. Tensile Strength [MPa]: 0.4. Elongation at Break [%]: 150. Elegonation with %: 150%. Categories: Oligomers. |  |
| BR-372 | Provides a balance of toughness and flexibility with very. low color; low skin sensitivity for dental and cosmetic. applications. Uses: Coatings, adhesives. Group: Oligomer. Oligomer Functionality: 2. Viscosity [CP]: 8,500 (Neat). Durometer Hardness: 65D. Tensile Strength [MPa]: 15. Elongation at Break [%]: 90. Elegonation with %: 90%. Categories: Oligomers. | |
| BR-541MB | High tensile strength; excellent optical clarity; low skin. sensitivity. Uses: Coatings, adhesives, 3d printing. Group: Oligomer. Oligomer Functionality: 2. Viscosity [CP]: 6,400 (Neat). Durometer Hardness: 74D. Tensile Strength [MPa]: 28. Elongation at Break [%]: 85. Elegonation with %: 85%. Categories: Oligomers. | |
| BR-543MB | Ideal for nail gel coatings; high tensile strength. excellent optical clarity; oil resistant; improves impact. resistance and adhesion; low skin sensitivity; exhibits. hydrolytic stability. Uses: Coatings, adhesives, 3d printing. Group: Oligomer. Oligomer Functionality: 2. Viscosity [CP]: 13,000 (Neat). Durometer Hardness: 74A. Tensile Strength [MPa]: 5. Elongation at Break [%]: 50. Elegonation with %: 50%. Categories: Oligomers. | |
| Cetrorelix Impurities | Cetrorelix Impurities hold vital significance in the assessment of purity and pharmacokinetic profiles of Cetrorelix, a GnRH antagonist pivotal for hormone-sensitive treatments such as prostate cancer and infertility. The exploration of these impurities enhances formulation refinement, ensuring therapeutic safety and efficacy, thus advancing pharmaceutical efficacy. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CH5424802 Hydrochloride | CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. Group: Pharmaceutical. CAS No. 1256589-74-8. Pack Sizes: 1 g. Product ID: B0084-463153. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Chrysin-7-O-glucuronide | Chrysin-7-O-glucuronide, a flavone compound derived from plants, has garnered attention for its therapeutic potential against cancer and diabetes. Prior investigations have demonstrated its ability to modulate the apoptotic pathways in cancer cells, leading to growth inhibition and reduced tumor progression. Furthermore, chrysin-7-O-glucuronide exhibits promising attributes as a glucose regulator, as evidenced by its capacity to enhance insulin sensitivity and support proper glucose metabolism. These findings collectively suggest chrysin-7-O-glucuronide as a worthy candidate for further exploration in the development of cancer and diabetes treatment. Group: Pharmaceutical. CAS No. 35775-49-6. Pack Sizes: 5 mg. Product ID: B2703-001241. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| CP-640186 | CP-640186 is a potent inhibitor of mammalian ACCs and can reduce body weight and improve insulin sensitivity in test animals. It has recently been shown to be a potent inhibitor of isoforms of mammalian ACCs. Most importantly, CP-640186 can reduce body fat mass and body weight, and improve insulin sensitivity, validating ACCs as targets for antiobesity and antidiabetes drugs. Group: Pharmaceutical. CAS No. 591778-68-6. Pack Sizes: 100 mg. Product ID: B2693-459321. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| DCC-2618 | DCC-2618 inhibits normal and mutant KIT kinase at the nanomol level. The targets are wt c-KIT, c-KIT mutants, PDGFR alpha, PDGFR beta, KDR and cFMS. DCC-2618 inhibits mutant KIT in GIST patient cell line (GIST T1 pKIT western Ex11 deletion) at a IC 50 of 2 nM. Deciphera's technology has identified DCC-2618 as a molecule which can be developed as second line therapy for imatinib and sunitinib resistant GIST patients with the potential to progress to frontline GIST therapy. DCC-2618 has been designed to effectively inhibit the imatinib and sunitinib-sensitive KIT juxtamembrane domain mutants (JMD) as well as secondary resistant KIT kinase-domain mutants. DCC-2618 additionally targets PDGFR alpha oncogenic mutants. Group: Pharmaceutical. CAS No. 1225278-16-9. Pack Sizes: 50 mg. Product ID: B0084-457687. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| DCPIB | DCPIB is a potent and selective volume-sensitive anion channel (VSAC) blocker, swell in various cardiovascular tissues (IC50 = 4.1 μM in CPAE cells). It inhibits glucose-stimulated insulin in intact β-cells, and reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro. Group: Pharmaceutical. CAS No. 82749-70-0. Pack Sizes: 50 mg. Product ID: B2693-034500. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Deep Blue Pro 1 Litre Summerlong | Summerlong Is a slow-release hlghly effective alglclde. One single 1 litre dose Is sufficient to control algae for between 3-6 months in a 14,500L pool. Use Summerlong as directed to control algae over the summer period. Summerlong is pH sensitive and should only be used on pool water maintained within a pH range of 7.2 -7.6. Do not add chlorine within 24 hours of using this product or dose this product within 24 hours of adding chlorine to the pool. Summerlong can be used on both chlorinated and brominated pools, both tiled and lined pools. Do not be use on pools using Revacil/Baquacil DIRECTIONS FOR USE Adjust pH to 7.2-7.6 Pour the required amount of Summerlong directly over the water inlets and leave filter plant running to ensure even distribution. Use a copper Pooltester to check Total Copper residual once per month. Add a repeat dose if residual is below 0.4mg/l. Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 0666186536520. MPN: DBPRCH041S. Brand: Deep Blue Pro. Categories: Pool Chemicals. |  Lincolnshire, Wiltshire, Online |
| Deep Blue Pro 1 Litre Winterlong | Wlnterlong Is a slow-release hlghly economical wlnterlser. One single 1ltr dose is sufficient to control algae for between 3-6 months In a 50 cubic meter (11,000gal) pool. Use Winterlong as directed to control most types of algae over the winter period. Winterlong is pH sensitive and should only be used on pool water maintained within a pH range of 7.2 -7.6. Do not add chlorine within 24 hours of using this product or dose this product within 24 hours of adding chlorine to the pool. Winterlong can be used on both chlorinated and bromlnated pools but should not be used on pools using Revacil/Baquacil DIRECTIONS FOR WINTER CLOSE DOWN OF YOUR POOL Increase the chlorine level in your pool to approximately 6ppm(parts per million). Adjust pH to 7.2-7.6. Pour the required amount of Winterlong directly over the water inlets and leave filter plant running for 8 hours to ensure even distribution. Check your pool in January and increase chlorine level to 6ppm. Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 0666186536599. MPN: DBPRCH107S. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro 6 x 1 Litre Summerlong 6L | Summerlong Is a slow-release hlghly effective alglclde. One single 1 litre dose Is sufficient to control algae for between 3-6 months in a 14,500L pool. Use Summerlong as directed to control algae over the summer period. Summerlong is pH sensitive and should only be used on pool water maintained within a pH range of 7.2 -7.6. Do not add chlorine within 24 hours of using this product or dose this product within 24 hours of adding chlorine to the pool. Summerlong can be used on both chlorinated and brominated pools, both tiled and lined pools. Do not be use on pools using Revacil/Baquacil DIRECTIONS FOR USE Adjust pH to 7.2-7.6 Pour the required amount of Summerlong directly over the water inlets and leave filter plant running to ensure even distribution. Use a copper Pooltester to check Total Copper residual once per month. Add a repeat dose if residual is below 0.4mg/l. Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 5060220074262. MPN: DBPRCH041. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Deep Blue Pro 6 x 1 Litre Winterlong | Wlnterlong Is a slow-release hlghly economical wlnterlser. One single 1ltr dose is sufficient to control algae for between 3-6 months In a 50 cubic meter (11,000gal) pool. Use Winterlong as directed to control most types of algae over the winter period. Winterlong is pH sensitive and should only be used on pool water maintained within a pH range of 7.2 -7.6. Do not add chlorine within 24 hours of using this product or dose this product within 24 hours of adding chlorine to the pool. Winterlong can be used on both chlorinated and bromlnated pools but should not be used on pools using Revacil/Baquacil DIRECTIONS FOR WINTER CLOSE DOWN OF YOUR POOL Increase the chlorine level in your pool to approximately 6ppm(parts per million). Adjust pH to 7.2-7.6. Pour the required amount of Winterlong directly over the water inlets and leave filter plant running for 8 hours to ensure even distribution. Check your pool in January and increase chlorine level to 6ppm. Uses: Swimming pools, hot tubs. Water balancing; fast delivery. Grades: A+. Product ID: 5060220075290. MPN: DBPRCH107. Brand: Deep Blue Pro. Categories: Pool Chemicals. | Lincolnshire, Wiltshire, Online |
| Enrofloxacin | Enrofloxacin is a fluoroquinolone antibiotic that prevents DNA superhelix and DNA synthesis by inhibiting bacterial DNA gyrase (a type II topoisomerase). It can be used for bacterial diseases caused by sensitive bacteria in livestock and small animals. Group: Pharmaceutical. CAS No. 93106-60-6. Pack Sizes: 100 g. Product ID: BBF-04643. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Erlotinib | Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib has been indicated for non-small cell lung cancer (NSCLC) and pancreatic cancer therapy. Group: Pharmaceutical. CAS No. 183321-74-6. Pack Sizes: 10 g. Product ID: NP3245. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Estriol Impurities | Estriol Impurities are critical in the pharmaceutical research sector for developing and refining estrogen-related drugs. These impurities aid in understanding estrogen hormone metabolism, contributing to treatments for menopausal symptoms, osteoporosis, and hormone-sensitive cancers, ensuring drug safety and efficacy in therapeutics related to estriol. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GalNAc-INF7 | GalNAc (N-Acetylgalactosamine) has been used as a targeting ligand in antisense oligonucleotides (ASO) and siRNA therapeutics. INF7 peptide is a glutamine-enriched analogue of the membrane-disruptive segment of HA2 (amino acids 1-23) with greater pH sensitivity. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B1370-410022. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gefitinib | Gefitinib is an antineoplastic drug. Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both the high and low EGFR-expressing cell lines including NR6, NR6M and NR6W cell lines. The phosphorylation sites Tyr1173 and Tyr992 are less sensitive requiring higher concentrations of Gefitinib for inhibition. Group: Pharmaceutical. CAS No. 184475-35-2. Pack Sizes: 5 g. Product ID: BBF-04570. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Gentamicin Sulfate | Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms. Uses: Broad-spectrum, aminoglycoside antibiotic. Group: Pharmaceutical. CAS No. 1405-41-0. Pack Sizes: 50 g. Product ID: BBF-05841. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| GW9508 | GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 100-fold selective against GPR120, and stimulates insulin secretion in a glucose-sensitive manner. GW9508 is commonly used in the treatment of type 2 diabetes. Group: Pharmaceutical. CAS No. 885101-89-3. Pack Sizes: 100 mg. Product ID: B0084-272136. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Hoechst 33342 | Hoechst 33258, also called Pibenzimol, an iodinated DNA-binding bibenzimidazole, is a cell dye for DNA quantitation which sensitizes DNA and cells to UVA. Group: Pharmaceutical. CAS No. 23491-52-3. Pack Sizes: 500 mg. Product ID: B2708-367394. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Icilin | Icilin is a synthetic CMR1/TRPM8 super agonist in CMR1-expressing HEK 293 cells (EC50 = 0.36 μM) more potently than menthol or low temperatures. Uses: Both heat sensitive (vr1) and cold-sensitive (cmr1 (rat); trpm8 (human)) receptors. Group: Pharmaceutical. CAS No. 36945-98-9. Pack Sizes: 50 mg. Product ID: B0084-113190. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| JRCure 369 | Extremely reactive photoinitiator which has almost identical photochemical properties and reactivity to 379. 369 is easily sensitized in the long wave UV by small amounts of thioxanthone. This sensitisation effect increases its reactivity significantly and leads to very high cure speeds that can be utilised in high-speed offset litho and flexo inks. Uses: Coatings, electronics. Group: Photoinitiator. CAS No. 119313-12-1. Categories: Photoinitiators. | |
| JRCure 379 | Extremely reactive photoinitiator which has almost identical photochemical properties and reactivity to 369. 379 is more soluble that 369 and is described as a low-emission amino ketone (LE-AK). 379 is easily sensitised in the long wave UV by small amounts of thioxanthone. This sensitisation effect increases its reactivity significantly and leads to very high cure speeds that can be utilised in high-speed offset litho and flexo inks. Uses: Graphic arts, coatings, electronics, digital inks. Group: Photoinitiator. CAS No. 119344-86-4. Pack Sizes: 20kg. Categories: Photoinitiators. | |
| JRCure 907 | Very efficient, fast curing photoinitiator which is especially good for curing cyan inks. 907 exhibits low yellowing which means it can be used in screen inks and white lacquers as well as its main application, resist inks. 907 is easily sensitised by small amounts (0.2-0.5%) of thioxanthones which significantly increase cure speed (e.g. adding 0.5% ITX to 2% 907 will more than double the cure speed). Uses: Electronics, adhesives. Group: Photoinitiator. CAS No. 71868-10-5. Pack Sizes: 20kg. Categories: Photoinitiators. | |
| JRCure DETX | Thioxanthone photoinitiator that is used widely to sensitise other photoinitiators when used at 0.2-0.5 wt% in UV/LED curable formulation. DETX absorbs at 395 nm which makes it compatible in LED applications. ITX and DETX exhibit similar reactivity and are used almost universally in ink formulations. Uses: Graphic arts, coatings, electronics, adhesives, digital inks. Group: Photoinitiator. CAS No. 82799-44-8. Pack Sizes: 20kg. Categories: Photoinitiators. | |
| JRCure ITX | Thioxanthone photoinitiator that is used widely to sensitise other photoinitiators when used at 0.2-0.5 wt% in UV/LED curable formulation. ITX absorbs long wave UV which leads to good through cure, good adhesion and makes it compatible in LED applications. ITX and DETX exhibit similar reactivity and are used almost universally in ink formulations. Uses: Graphic arts, coatings, electronics, adhesives, digital inks. Group: Photoinitiator. CAS No. 5495-84-1. Pack Sizes: 20kg. Categories: Photoinitiators. | |
| Karakoline | Alkaloid , from plants of the Ranunculaceae family. Ganglioblocker; nicotinic receptor antagonist; hypotensive; presents micromolar affinity at brain a Bungarotoxin-sensitive nAChR. (See attached sheet.). Group: Pharmaceutical. CAS No. 39089-30-0. Pack Sizes: 20 mg. Product ID: B0005-115266. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Milbemycin oxime | Milbemycin oxime is a semi-synthetic macrolide. As a nematocide and insecticide in veterinary medicine, it opens glutamate sensitive chloride channels in neurons of invertebrates that leads to paralysis by hyperpolarisation of these cells and signal transfer blocking. M1-family aminopeptidase: IC50=2.6 μM (Plasmodium falciparum 3D7); Bile acid transporter: IC50=3.6 μM (human); TGR5: IC50=36.4 μM (human); HCT-116: IC50 >50 μM (human); GBM: IC50 >50 μM (human). Uses: A broad spectrum insecticide; used for treatment and prevention of heartworm in dogs and cats. Group: Pharmaceutical. CAS No. 129496-10-2. Pack Sizes: 500 mg. Product ID: BBF-03816. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Minoxidil Sulfate | Minoxidil sulfate is the active metabolite of Minoxidil and it is a potent vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener. Group: Pharmaceutical. CAS No. 83701-22-8. Pack Sizes: 100 g. Product ID: B2694-078174. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| MK-1775 | MK-1775, also known as AZD-1775, is a WEE1 inhibitor and a small-molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDC2) to inactivate the CDC2/cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents. Unlike normal cells, most p53-deficient or mutated human cancers lack the G1 checkpoint as p53 is the key regulator of the G1 checkpoint and these cells rely on the G2 checkpoint for DNA repair to damaged cells. Annulment of the G2 checkpoint may therefore make p53-deficient tumor cells more vulnerable to antineoplastic agents and enhance their cytotoxic effect. Group: Pharmaceutical. CAS No. 955365-80-7. Pack Sizes: 300 mg. Product ID: B0084-157422. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Oleandrin | Oleandrin, also known as PBI-05204, is a lipid soluble cardiac glycoside with potential antineoplastic activity. Upon administration, oleandrin specifically binds to and inhibits the alpha3 subunit of the Na/K-ATPase pump in human cancer cells. This may inhibit the phosphorylation of Akt, upregulate MAPK, inhibit NF-kb activation and inhibit FGF-2 export and may downregulate mTOR thereby inhibiting p70S6K and S6 protein expression. All of this may lead to an induction of apoptosis. As cancer cells with relatively higher expression of the alpha3 subunit and with limited expression of the alpha1 subunit more sensitive to oleandrin, one may predict the tumor response to treatment with lipid-soluble cardiac glycosides such as oleandrin based on the tumors Na/K-ATPase pump protein subunit expression. Overexpression of the alpha3 subunit in tumor cells correlates with tumor proliferation. Uses: Anti-proliferative. Group: Pharmaceutical. CAS No. 465-16-7. Pack Sizes: 10 mg. Product ID: NP6109. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| omega conotoxin MVIIA | ω conotoxin MVIIA (omega conotoxin MVIIA) has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). Group: Pharmaceutical. CAS No. 107452-89-1. Pack Sizes: 1 mg. Product ID: BAT-006118. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Oncrasin-1 | Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations. It also led to abnormal aggregation of PKCΙ in nucleus of sensitive cells but not in resistant cells. Group: Pharmaceutical. CAS No. 75629-57-1. Pack Sizes: 50 mg. Product ID: B1370-379298. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| P22077 | P22077 is a potent and selective ubiquitin-specific protease 7 (USP7) inhibitor. P22077 potently induces apoptosis in NB cells with an intact USP7-HDM2-p53 axis but not in NB cells with mutant p53 or without human homolog of MDM2 (HDM2) expression. P22077 was found to be able to sensitize chemoresistant LA-N-6 NB cells to chemotherapy. In an in vivo orthotopic NB mouse model, P22077 significantly inhibited the xenograft growth of three NB cell lines. USP7-specific inhibitors like P22077 may serve not only as a stand-alone therapy but also as an effective adjunct to current chemotherapeutic regimens for treating NB with an intact USP7-HDM2-p53 axis. Group: Pharmaceutical. CAS No. 1247819-59-5. Pack Sizes: 100 mg. Product ID: B0084-462597. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pimonidazole | Pimonidazole, also known as Ro 03-8799 and PD 126675, is a nitroimidazole drug with hypoxic selectivity and radiosensitizing property. Pimonidazole is reduced in hypoxic environments as in tumor cells, thereby it can be used as an hypoxia marker. In hypoxic cells, reduced pimonidazole binds to -SH-containing molecules such as glutathione and proteins, and the resulting complexes accumulated in tissues, thereby sensitizing cells to be more susceptible for radiation treatment. Group: Pharmaceutical. CAS No. 70132-50-2. Pack Sizes: 100 mg. Product ID: B1370-181685. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pseudoginsenoside-F11 | Pseudoginsenoside- F11 is extracted from the roots of Panax ginseng C. A. Mey. It antagonized the memory dysfunction induced by scopolamine. It has been shown to antagonize the behavioral actions of morphine. It may block the development of morphine-induced behavioral sensitization via its effect, at least partially, on the glutamatergic system in the medial prefrontal cortex (mPFC). Uses: An oxotillol-type ginsenoside which displayes neuroprotective activity. Group: Pharmaceutical. CAS No. 69884-00-0. Pack Sizes: 20 mg. Product ID: NP7216. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PTZ-343 | It acts as an HRP chemiluminescence enhancer. In the configuration of chemiluminescence substrate A/B solution, the addition of a certain amount of enhancer is helpful to enhance the luminescence intensity and sensitivity. Uses: For research use only. Group: Pharmaceutical. CAS No. 101199-38-6. Pack Sizes: 1 g. Product ID: B0084-220931. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rebaudioside M | Rebaudioside M is a natural sweetener extracted from the stevia plant. It is commonly used as a substitute for sugar in various food and beverage products due to its high sweetness and low calorie content. Additionally, studies have shown that rebaudioside M may have potential applications in the treatment of diabetes and obesity due to its ability to regulate blood sugar levels and improve insulin sensitivity. Group: Pharmaceutical. CAS No. 1220616-44-3. Pack Sizes: 10 mg. Product ID: B2705-003561. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| RETF-4NA | RETF-4NA is a sensitive substrate for chymase when free or bound to α2M. It is selectively hydrolyzed by chymase but not by cathepsin G. Group: Pharmaceutical. CAS No. 1160928-63-1. Pack Sizes: 10 mg. Product ID: BAT-010838. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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