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(14R)-paricalcitol is an isomer of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B0075-054110. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1α-Hydroxy VD4
1α-Hydroxy VD4 is an analogue of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Group: Pharmaceutical. CAS No. 143032-85-3. Pack Sizes: 1 mg. Product ID: B1959-054064. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
1β-doxercalciferol
1β-doxercalciferol is an isomer of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Group: Pharmaceutical. CAS No. 127516-23-8. Pack Sizes: 1 mg. Product ID: B1959-262189. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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1β-maxacalcitol
1β-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 169218-34-2. Pack Sizes: 5 mg. Product ID: B1128-054106. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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1β-trans-maxacalcitol
1β-trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B1128-054103. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(20R)-1β-maxacalcitol
(20R)-1β-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 2 mg. Product ID: B1128-054099. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(20R)-1β-trans-maxacalcitol
(20R)-1β-trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 2 mg. Product ID: B1128-054102. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(20R)-trans-maxacalcitol
(20R)-trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: B1128-054096. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(20S)-paricalcitol
(20S)-paricalcitol is an isomer of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B0075-054109. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
(24R)-paricalcitol
(24R)-paricalcitol is an isomer of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 132015-95-3. Pack Sizes: 5 mg. Product ID: B0075-054107. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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3α-paricalcitol
3α-paricalcitol is an isomer of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 216161-87-4. Pack Sizes: 5 mg. Product ID: B0075-054116. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Altenuene Impurities
Altenuene Impurities are secondary metabolites found in the study of certain fungal species. Primarily utilized in biomedical research, they serve as tools for understanding fungal biosynthetic pathways and their potential impact on human health. These impurities are particularly significant in investigations related to fungal toxin production and contamination in pharmaceuticals. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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ARV-825
ARV-825 is a BRD4 inhibitor based on PROTAC technology. ARV-825 recruits BRD4 to E3 ubiquitin ligase cereblon, resulting in the degradation of BRD4. In post-myeloproliferative neoplasm secondary (s) AML cell lines, treatment with ARV-825 induces apoptosis and inhibits cell proliferation. Group: Pharmaceutical. CAS No. 1818885-28-7. Pack Sizes: 100 mg. Product ID: B1370-474664. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Balanol Impurities
Balanol Impurities, integral to pharmaceutical R&D, are paramount for elucidating enzyme inhibitor characteristics. These secondary compounds illuminate kinase modulation, essential for innovating oncology and metabolic disorder therapies. Their meticulous analysis enhances drug formulation refinement, ensuring robust pharmacological efficacy, and advancing therapeutic precision. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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β-Aflatrem
β-Aflatrem is a class of structurally-diverse secondary metabolites isolated from Aspergillus flavus. It is a mycotoxin that exhibits insecticidal activity. Group: Pharmaceutical. CAS No. 144446-23-1. Pack Sizes: 1 mg. Product ID: BBF-04461. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Cinacalcet Impurities
Cinacalcet Impurities serve as essential analytical standards, deeply embedded in the rigorous quality control and characterization processes of Cinacalcet. Integral to combating secondary hyperparathyroidism and parathyroid carcinoma, they necessitate precise impurity analysis to ensure safety, therapeutic efficacy, and compliance with regulatory parameters, vital in the pharmaceutical developmental trajectory. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Cinacalcet Impurity 18
An impurity of Cinacalcet, a medication used in the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 1020414-30-5. Pack Sizes: 100 mg. Product ID: B2694-468985. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Cinacalcet Impurity 7
An impurity of Cinacalcet, a medication used in the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 21172-43-0. Pack Sizes: 50 mg. Product ID: B2694-468971. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Cinacalcet Impurity B (HCl salt form)
Cinacalcet Impurity B (HCl salt form) is an impurity of Cinacalcet, a medication used to treat secondary hyperparathyroidism in patients with chronic kidney disease and parathyroid carcinoma. Group: Pharmaceutical. CAS No. 163831-65-0. Pack Sizes: 50 mg. Product ID: B0041-237437. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Cinacalcet Impurity D
N-[(3-Trifluoromethyl)phenyl)propyl] Cinacalcet is an impurity of Cinacalcet Hydrochloride. Cinacalcet is used in clinical trial in secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 1271930-15-4. Pack Sizes: 50 mg. Product ID: B0041-468972. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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DCC-2618
DCC-2618 inhibits normal and mutant KIT kinase at the nanomol level. The targets are wt c-KIT, c-KIT mutants, PDGFR alpha, PDGFR beta, KDR and cFMS. DCC-2618 inhibits mutant KIT in GIST patient cell line (GIST T1 pKIT western Ex11 deletion) at a IC 50 of 2 nM. Deciphera's technology has identified DCC-2618 as a molecule which can be developed as second line therapy for imatinib and sunitinib resistant GIST patients with the potential to progress to frontline GIST therapy. DCC-2618 has been designed to effectively inhibit the imatinib and sunitinib-sensitive KIT juxtamembrane domain mutants (JMD) as well as secondary resistant KIT kinase-domain mutants. DCC-2618 additionally targets PDGFR alpha oncogenic mutants. Group: Pharmaceutical. CAS No. 1225278-16-9. Pack Sizes: 50 mg. Product ID: B0084-457687. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Denibulin
Denibulin (MN-029) is a novel vascular-disrupting agent that reversibly inhibits microtubule assembly, resulting in disruption of the cytoskeleton of tumor vascular endothelial cells. The results of preclinical study demonstrated that MN-029 could cause rapid vascular shutdown in solid tumors, dose-dependent secondary tumor cell killing, and effective enhancement of the antitumor effects of radiation and cisplatin chemotherapy. Group: Pharmaceutical. CAS No. 284019-34-7. Pack Sizes: 1 mg. Product ID: B1370-065073. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Dimethylamine
A organic compound with the formula (CH3)2NH. This secondary amine is a colourless, flammable gas with an ammonia-like odour. Dimethylamine is commonly encountered commercially as a solution in water at concentrations up to around 40%. Uses: Laboratory chemicals, Manufacture of substances. CAS No. 124-40-3.
ent-Cinacalcet Hydrochloride
ent-Cinacalcet Hydrochloride is the (S) enantiomer of Cinacalcet. It is used in clinical trial in secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 694495-47-1. Pack Sizes: 25 mg. Product ID: B1370-468966. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Estradiol
Estradiol, or more precisely, 17β-estradiol, is a human sex hormone and steroid, and the primary female sex hormone. It is essential for the maintenance of fertility and secondary sexual characteristics in females. Uses: Human sex hormone. Group: Pharmaceutical. CAS No. 50-28-2. Pack Sizes: 25 g. Product ID: NP6102. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Etelcalcetide hydrochloride
Etelcalcetide is a calcium-sensing receptor agonist as a D-amino peptide calcimimetic for the treatment of secondary hyperparathyroidism. It can bind to and activate the CaSR (calcium-sensing receptor) in the parathyroid gland as an allosteric activator, resulting in PTH reduction and suppression. Amgen Inc. announced its submission of a New Drug Application to the FDA for etelcalcetide in Aug 2015. Group: Pharmaceutical. CAS No. 1334237-71-6. Pack Sizes: 10 mg. Product ID: B0084-475311. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Isopropyl alcohol
Is a colourless, flammable organic compound (chemical formula CH3CHOHCH3) with a strong alcoholic odour. As an isopropyl group linked to a hydroxyl group, it is the simplest example of a secondary alcohol, where the alcohol carbon atom is attached to two other carbon atoms. Uses: Laboratory chemicals, Industrial & for professional use. Alternative Names: IUPAC name propan-2-ol and also called isopropanol or 2-propanol. CAS No. 67-63-0.
LanCos EMCS, INCI Name: Cetearyl Alcohol
LanCos EMCS is a blend of cetyl and stearyl alcohol, used as a secondary emulsifier and viscosity modifier in various skin care products. It is also commonly used as an opacifier in hair shampoos and conditioners. INCI Name = International Nomenclature of Cosmetic Ingredients. Personal Care Products. Formerly Lansdowne Chemicals
Lancos UVB-3 benzophenone-3 is a secondary UV-B absorbers and is the most widely used organic compound in sunscreens and other cosmetics to protect from sun rays. It provides supplemental UV protection, boosts SPF activity and is globally approved. INCI Name = International Nomenclature of Cosmetic Ingredients. Personal Care Products. Formerly Lansdowne Chemicals
LanCos UVB-4 is a water soluble secondary UV-B absorbers which can be used at very low levels to protect the integrity of other cosmetic ingredients from deteriorating under the suns rays, such as with the colour of products in clear packaging. It is commonly used in sunscreen, nail polish, lotions, creams and lipstick products. INCI Name = International Nomenclature of Cosmetic Ingredients. Personal Care Products. Formerly Lansdowne Chemicals
LanCos UVB benzophenone flakes as a secondary UV-B absorbers are used to prevent ultraviolet light from damaging scents and colours in products such as perfumes and soaps. INCI Name = International Nomenclature of Cosmetic Ingredients. Personal Care Products. Formerly Lansdowne Chemicals
Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity, its toxic effect can be protected after it activates the vitamin D receptor, PXR and FXR. Uses: Detergents. Group: Pharmaceutical. CAS No. 434-13-9. Pack Sizes: 50 g. Product ID: NP6107. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Maxacalcitol Impurities
Maxacalcitol Impurities occupy a crucial role in the quality assurance protocols of Maxacalcitol synthesis, a synthetic vitamin D derivative utilized for managing psoriasis and secondary hyperparathyroidism. Insight into these impurities is vital for augmenting the compound's potency and safety, thereby guaranteeing superior therapeutic results for affected patients. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Maxacalcitol Intermediate
An intermediate of maxacalcitol, which is a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. Pack Sizes: 5 mg. Product ID: B1128-112381. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
m-Methoxytopolin riboside
It can be used in biological study in influence of plant growth regulators on shoot proliferation and secondary metabolite production in micropropagated Huernia hystrix. Group: Pharmaceutical. CAS No. 101565-95-1. Pack Sizes: 1 g. Product ID: B2706-291769. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Ozanimod
Ozanimod is a medication used for the treatment of multiple sclerosis (MS) and inflammatory bowel disease (IBD), specifically ulcerative colitis. Ozanimod is a selective sphingosine 1-phosphate (S1P) receptor modulator. It binds to S1P receptors on lymphocytes (a type of white blood cell), thereby inhibiting their egress from lymph nodes. This action reduces the number of circulating lymphocytes that can cause inflammation in the central nervous system (in the case of MS) or the intestines (in the case of ulcerative colitis). Ozanimod is indicated for the treatment of relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. It is also approved for the treatment of moderate to severe ulcerative colitis in adults who have not responded adequately to conventional therapies. Group: Pharmaceutical. CAS No. 1306760-87-1. Pack Sizes: 50 mg. Product ID: B0084-470834. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Paricalcitol Impurities
Paricalcitol Impurities hold significant importance within the pharmaceutical sector, utilized meticulously to evaluate the purity and stability of paricalcitol formulations. As paricalcitol addresses secondary hyperparathyroidism in chronic kidney disease patients, impurity monitoring is crucial for ensuring therapeutic effectiveness and safety, hence facilitating drug development and regulatory adherence. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Paricalcitol Impurity 4
Paricalcitol Impurity 4 is an impurity of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 95716-68-0. Pack Sizes: 25 mg. Product ID: B0075-460980. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Paricalcitol Intermediate A
Paricalcitol Intermediate A is an intermediate of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 139356-39-1. Pack Sizes: 250 mg. Product ID: B0075-457976. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Paricalcitol Intermediate CD
Paricalcitol Intermediate CD is an intermediate of paricalcitol, an analogue of vitamin D2. Paricalcitol is a medication used for the treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 95716-69-1. Pack Sizes: 100 mg. Product ID: B0075-112382. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Picein Impurities
Picein Impurities are secondary components found in picein, utilized in pharmaceutical analysis and quality control. They help in evaluating drug purity and stability, particularly in compounds targeting inflammatory diseases. Additionally, these impurities aid in understanding picein's pharmacokinetic properties for the development of more effective therapeutic agents. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
(R)-1- (Naphthalen-1-yl)-N- (3- (trifluoromethyl)benzyl)ethanamine hydrochloride, is an impurity of Cinacalcet, which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels). Group: Pharmaceutical. CAS No. 1229225-42-6. Pack Sizes: 10 mg. Product ID: B2694-379696. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Siponimod
Siponimod is a selective S1P1 and S1P5 agonist with EC50 of 0.39 nM and 0.98 nM, respectively. It has been approved by US FDA for the treatment of patients with active secondary progressive multiple sclerosis (SPMS). Group: Pharmaceutical. CAS No. 1230487-00-9. Pack Sizes: 100 mg. Product ID: B0084-463380. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
trans-Clomiphene Citrate
Enclomiphene citrateis a non-steroidal estrogen receptor antagonist. It can be used for secondary hypogonadism in overweight men wishing to restore normal testicular function. Uses: Restore testicular function. Group: Pharmaceutical. CAS No. 7599-79-3. Pack Sizes: 2.5 mg. Product ID: B0084-476606. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
trans-doxercalciferol
Trans-doxercalciferol is an isomer of doxercalciferol, a drug used for the treatment of secondary hyperparathyroidism and metabolic bone disease. Group: Pharmaceutical. CAS No. 74007-20-8. Pack Sizes: 5 mg. Product ID: B1959-261135. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
trans-maxacalcitol
Trans-maxacalcitol is an isomer of maxacalcitol, a derivative of vitamin D3. Maxacalcitol is a potential treatment of secondary hyperparathyroidism. Group: Pharmaceutical. CAS No. 929721-98-2. Pack Sizes: 1 mg. Product ID: B1128-054098. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Urolithin A
Urolithin A is a secondary metabolite of ellagitannins by the gut bacteria. It exhibits anti-inflammatory, antioxidant and antiproliferative effects. Urolithin A can cross the blood brain barrier thus has the potential therapeutic effect against Alzheimer's Disease. Group: Pharmaceutical. CAS No. 1143-70-0. Pack Sizes: 1 g. Product ID: BBF-04125. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Vorapaxar
SCH-530348 is a novel antiplatelet agent undergoing development by Schering-Plough Corp for the treatment and prevention of atherothrombosis. It is currently undergoing Phase-III clinical trials for acute coronary syndrome (unstable angina/non-ST segment elevation myocardial infarction) and secondary prevention of cardiovascular events in high-risk patients. Uses: Platelet aggregation inhibitors. Group: Pharmaceutical. CAS No. 618385-01-6. Pack Sizes: 10 mg. Product ID: B0084-458444. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
XL147
Pilaralisib is a Class 1 phosphatidylinositol 3 kinase (PI3K) family inhibitor. It is an orally bioavailable small molecule, targeting the class I PI3K family of lipid kinases. It is a pyrimidine derivatives compound discovered by Exelixis Inc. It has potential antineoplastic activity. It binds to class 1 PI3Ks in an ATP-competitive manner by inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and inhibiting the activation of the PI3K signaling pathway. Uses: Pilaralisib has potential antineoplastic activity. Group: Pharmaceutical. CAS No. 956958-53-5. Pack Sizes: 300 mg. Product ID: B0084-258924. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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