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| Product | Description | |
|---|---|---|
| Sacubitril | Sacubitril, also known as AHU377 or LCZ696, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume. Group: Pharmaceutical. CAS No. 149709-62-6. Pack Sizes: 10 g. Product ID: B0084-458470. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| Sacubitril-(2S, 4S)-Isomer | Sacubitril-(2S, 4S)-isomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Group: Pharmaceutical. CAS No. 149709-63-7. Pack Sizes: 50 mg. Product ID: B2694-479383. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril-[d4] | An isotope labelled AHU377, a methyl ester prodrug form of the neprilysin inhibitor LBQ657. Group: Pharmaceutical. CAS No. 1884269-07-1. Pack Sizes: 10 mg. Product ID: BLP-009582. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril Enantiomer | Sacubitril enantiomer.Sacubitril is a prodrug neprilysin inhibitor used in combination with valsartan to reduce the risk of cardiovascular events in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. Group: Pharmaceutical. CAS No. 761373-05-1. Pack Sizes: 25 mg. Product ID: B2694-479381. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril Impurities | Sacubitril Impurities are integral in advancing heart failure treatment methodologies, especially with angiotensin receptor-neprilysin inhibitors (ARNIs). These impurities aid in evaluating Sacubitril's purity and potency, ensuring therapeutic safety and efficacy, thereby underpinning the pharmaceutical framework for cardiovascular therapy innovations. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril Impurity 3 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Group: Pharmaceutical. CAS No. 1038925-00-6. Pack Sizes: 10 mg. Product ID: B2694-479387. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril Impurity 4 | Sacubitrilat is one of the impurities of Sacubitril which has been found to be an endopeptidase inhibitor and be effective in the treatment of hypertension and heart failure. Group: Pharmaceutical. CAS No. 149709-44-4. Pack Sizes: 100 mg. Product ID: B0084-475830. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril Impurity 5 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Group: Pharmaceutical. CAS No. 1012341-56-8. Pack Sizes: 5 mg. Product ID: B2694-479391. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril Impurity 6 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Group: Pharmaceutical. CAS No. 1012341-54-6. Pack Sizes: 5 mg. Product ID: B2694-479392. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril Impurity 7 | An impurity of sacubitril. Sacubitril is an antihypertensive drug used in combination with valsartan. Group: Pharmaceutical. CAS No. 1012341-52-4. Pack Sizes: 5 mg. Product ID: B2694-479393. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Sacubitril sodium | Sacubitril, also known as AHU377, is a first-in-class medicine that contains a neprilysin (NEP) inhibitor (sacubitril) and an angiotensin II (Ang-II) receptor blocker (valsartan). Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. Group: Pharmaceutical. CAS No. 149690-05-1. Pack Sizes: 500 mg. Product ID: B0084-007864. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 2,5-Dioxopyrrolidine Sacubitril | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. CAS No. 1038924-97-8. Pack Sizes: 100 mg. Product ID: B1604-479386. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (2R,4S)-4-Amino-5-biphenyl-4-yl-2-methylpentanoic acid hydrochloride | An impurity of Sacubitril, a neprilysin inhibitor that is used in combination with valsartan to treat high blood pressure. Group: Pharmaceutical. CAS No. 1038924-71-8. Pack Sizes: 100 mg. Product ID: B2694-013668. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (2R,4S)-5-Biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methylpentanoic acid | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. CAS No. 1012341-50-2. Pack Sizes: 100 mg. Product ID: B1604-479394. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (3R,5S)-5-Biphenyl-4-ylmethyl-3-methylpyrrolidin-2-one | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. CAS No. 1038924-70-7. Pack Sizes: 100 mg. Product ID: B1604-479385. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| ((R)-2-Biphenyl-4-yl-1-formylethyl)carbamic Acid t-Butyl Ester | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. CAS No. 149709-58-0. Pack Sizes: 100 mg. Product ID: B1604-284931. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| (R)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate | An impurity of Sacubitril, which is an antihypertensive. The combination drug of sacubitril and valsartan is used for heart failure. Group: Pharmaceutical. CAS No. 149709-59-1. Pack Sizes: 100 mg. Product ID: B1604-284930. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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