Find where to buy products from UK suppliers, including: distributors, industrial manufacturers, wholesalers, raw ingredients, bulk supplies and finished goods for sale.
Search for products or services, then visit the suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the USA.
| Product | Description | |
|---|---|---|
| Ruxolitinib | Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50 values of 3.3 nM and 2.8 nM respectively in cell-free assays, and has > 130-fold selectivity for JAK1/2 versus JAK3. Group: Pharmaceutical. Alternative Names: (R)-Ruxolitinib; INCB018424; R-INCB018424; (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile. CAS No. 941678-49-5. Pack Sizes: 200 mg. Product ID: B0084-156872. Molecular formula: C17H18N6. Mole weight: 306.37. Custom synthesis is available. Send your inquiries for more information. |  London |
| Ruxolitinib phosphate | Ruxolitinib phosphate is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Group: Pharmaceutical. Alternative Names: INCB018424 phosphate; INCB 018424 phosphate; INCB-018424 phosphate. CAS No. 1092939-17-7. Pack Sizes: 200 mg. Product ID: B0084-321795. Molecular formula: C17H21N6O4P. Mole weight: 404.36. Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-Ruxolitinib | Ruxolitinib S enantiomer, the chirality of INCB018424, is a potent and selective small-molecule Janus kinase 1 (JAK1) and JAK2 inhibitor to enter the clinic. It was initially developed to target the constitutive activation of the JAK-STAT pathway. It maintains its anti-JAK activity by competitive inhibition of the ATP-binding catalytic site of the kinase domain. It is well absorbed at above 95%. Group: Pharmaceutical. Alternative Names: Ruxolitinib (S enantiomer); (S)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile. CAS No. 941685-37-6. Pack Sizes: 100 mg. Product ID: B1370-122866. Molecular formula: C17H18N6. Mole weight: 306.37. Custom synthesis is available. Send your inquiries for more information. | London |
| (S)-Ruxolitinib Phosphate | (S)-Ruxolitinib Phosphate is an impurity of Ruxolitinib phosphate. Ruxolitinib phosphate is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Group: Pharmaceutical. Alternative Names: Ruxolitinib (S)-Isomer Phosphate; (S)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile Phosphate. CAS No. 2703484-89-1. Pack Sizes: 25 mg. Product ID: B1370-099085. Molecular formula: C17H21N6O4P. Mole weight: 404.37. Custom synthesis is available. Send your inquiries for more information. | London |
Our database is helping our users find suppliers everyday.
