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| Product | Description | |
|---|---|---|
| (17R,19E,21alpha)-17-acetoxy-1,2,19,20-tetradehydro-1-demethylajmalan-21-yl beta-D-glucopyranoside | Raucaffricine is a natural alkaloid found in the root of Rauvolfia serpentina. Group: Pharmaceutical. Alternative Names: (17R,19E,21alpha)-17-acetoxy-1,2,19,20-tetradehydro-1-demethylajmalan-21-yl beta-D-glucopyranoside. CAS No. 31282-07-2. Pack Sizes: 5 mg. Product ID: NP0398. Molecular formula: C27H32N2O8. Mole weight: 512.56. Custom synthesis is available. Send your inquiries for more information. |  London |
| 2'-O-Methylisoliquiritigenin | 2'-O-Methylisoliquiritigenin is isolated from the roots of Glycyrrhiza glabra L. Group: Pharmaceutical. Alternative Names: Isoliquiritigenin 2'-methyl ether. CAS No. 51828-10-5. Pack Sizes: 5 mg. Product ID: NP0956. Molecular formula: C16H14O4. Mole weight: 270.3. Custom synthesis is available. Send your inquiries for more information. | London |
| 3-Methyladenine | 3-Methyladenine is an autophagy inhibitor that protects cerebellar granule cells (CGCs) from apoptosis following serum/potassium deprivation. 3-Methyladenine inhibits phosphoinositide 3-kinase (PI3K) activity, which plays a key role in autophagy process. Group: Pharmaceutical. Alternative Names: NSC 66389; NSC-66389; NSC66389; 6-Amino-3-methylpurine; 3-MA; 3H-Purin-6-amine, 3-methyl-; 3-Methyl Adenine; 3-Methyl-6-aminopurine; N3-Methyladenine. CAS No. 5142-23-4. Pack Sizes: 250 mg. Product ID: B0084-070159. Molecular formula: C6H7N5. Mole weight: 149.15. Custom synthesis is available. Send your inquiries for more information. | London |
| Angiotensin A | Angiotensin A is a potent endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. It shows similar affinity for AT1 and AT2 receptors as angiotensin II with Ki values of 1.6 and 2.3 nM in vitro. It causes pressor and renal vasoconstrictor effects in rodents by the AT1 receptor. It is inhibited by Candesartan but not by AT2 receptor ligands in vivo. It also increases inositol phosphate accumulation with a similar potency to Ang II with EC50 value of 6.7 nM. Group: Pharmaceutical. Alternative Names: Ala-Angiotensin III; H-Ala-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; Ang A; Angiotensin II, 1-L-alanine-5-L-isoleucine-; L-alanyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine. CAS No. 51833-76-2. Pack Sizes: 10 mg. Product ID: BAT-015367. Molecular formula: C49H71N13O10. Mole weight: 1002.18. Custom synthesis is available. Send your inquiries for more information. | London |
| Avapritinib | BLU-285 is a potent and selective inhibitor of exon 17 mutant KIT (IC50 = 0.27 nM for KIT D816V). BLU-285 showed dose-dependent, robust anti-tumor efficacy in a TKI-resistant KIT exon 11/17 mutant GIST PDX model through inhibition of tumor growth, proliferation, KIT signaling and induction of apoptosis. Group: Pharmaceutical. Alternative Names: (1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine; BLU-285; BLU 285; BLU285; UNII-513P80B4YJ; SCHEMBL16652297. CAS No. 1703793-34-3. Pack Sizes: 10 mg. Product ID: B0084-007732. Molecular formula: C26H27FN10. Mole weight: 498.56. Custom synthesis is available. Send your inquiries for more information. | London |
| Basmisanil | Basmisanil is a highly selective inverse agonist/negative allosteric modulator GABAAα5 receptors. It was developed by Roche to treat cognitive impairment associated with Down syndrome. In Apr 2016, Roche completed the phase II in Down syndrome (In adolescents, In adults) in USA, Argentina, Canada, France, Italy, Mexico, New Zealand, Singapore, Spain and the UK. In Sep 2016, Phase-II clinical trials in Neurological disorders (In adults, In the elderly) in Spain was on going. Uses: Down syndrome; neurological disorders. Group: Pharmaceutical. Alternative Names: (1,1-dioxidothiomorpholino)(6-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)pyridin-3-yl)methanone; RG 1662; RG-1662; RG1662; RO5186582; RO-5186582; RO 5186582. CAS No. 1159600-41-5. Pack Sizes: 100 mg. Product ID: B2693-475111. Molecular formula: C21H20FN3O5S. Mole weight: 445.47. Custom synthesis is available. Send your inquiries for more information. | London |
| CH5424802 Hydrochloride | CH5424802 Hcl (AF 802 Hcl; Alectinib Hcl) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. Group: Pharmaceutical. Alternative Names: Alectinib Hydrochloride; AF-802 Hydrochloride; CH-5424802 Hydrochloride; RG-7853 Hydrochloride; RO-5424802 Hydrochloride; AF 802 Hydrochloride; CH 5424802 Hydrochloride; RG 7853 Hydrochloride; RO 5424802 Hydrochloride; AF802 Hydrochloride; CH5424802 Hydrochloride; RG7853 Hydrochloride; RO5424802 Hydrochloride. CAS No. 1256589-74-8. Pack Sizes: 1 g. Product ID: B0084-463153. Molecular formula: C30H35ClN4O2. Mole weight: 519.08. Custom synthesis is available. Send your inquiries for more information. | London |
| Dihydrooxoepistephamiersine | Dihydrooxoepistephamiersine is a natural alkaloid found in the root of Stephania japonica. Group: Pharmaceutical. Alternative Names: (6β,7β,8β,10β)-6-Hydroxy-3,4,7,8-tetramethoxy-17-methyl-8,10-epox yhasubanan-16-one. CAS No. 51804-69-4. Pack Sizes: 1 mg. Product ID: NP0384. Molecular formula: C21H27NO7. Mole weight: 405.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Ebselen | Ebselen, also known as SPI-1005, is an organoselenium compound with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administration of SPI-1005, this agent mimics the activity of glutathione peroxidase (GPx) and can utilize glutathione to reduce other unstable molecules, thus preventing the formation of reactive oxygen species (ROS) and reducing oxidative stress on the cell. In the cochlea, this agent may prevent drug-induced injury to the auditory hair cells thereby preventing hearing loss. GPx is the main antioxidant enzyme in the cochlea and protects the inner ear from loud sounds and biochemical damage. In addition, ebselen is able to inhibit the activity of many enzymes involved in inflammation. Group: Pharmaceutical. Alternative Names: SPI-1005; SPI1005; SPI 1005; Ebselen; PZ 51; PZ51; PZ-51; DR3305; DR 3305; DR-3305. CAS No. 60940-34-3. Pack Sizes: 1 g. Product ID: B2693-072972. Molecular formula: C13H9NOSe. Mole weight: 274.192. Custom synthesis is available. Send your inquiries for more information. | London |
| Emodin | Emodin is an anthraquinone found naturally in the roots and barks of numerous plants. It exerts antiproliferative effects in cancer cells that are regulated by different signaling pathways. It has anti-cancer, anti-depressant and anti-microbial effects. Group: Pharmaceutical. Alternative Names: Emodol; Frangula emodin; HSDB 7093; NSC 408120; NSC 622947; 3-methyl-1,6,8-trihydroxyanthraquinone; 1,3,8-Trihydroxy-6-methyl-9,10-anthracenedione; 1,6,8-Trihydroxy-3-methylanthraquinone; 4,5,7-Trihydroxy-2-methylanthraquinone; Archin; Frangulic Acid; Rheum Emodin; Schuttgelb. CAS No. 518-82-1. Pack Sizes: 50 g. Product ID: BBF-04483. Molecular formula: C15H10O5. Mole weight: 270.24. Custom synthesis is available. Send your inquiries for more information. | London |
| Ixazomib Citrate | The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM. Group: Pharmaceutical. Alternative Names: 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; MLN9708; MLN-9708; MLN 9708. CAS No. 1239908-20-3. Pack Sizes: 100 mg. Product ID: BBF-04173. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. Custom synthesis is available. Send your inquiries for more information. | London |
| L-Hydroxyproline | L-Hydroxyproline is an amino acid. It can be used as a nutrition and a flavor enhancer. Uses: L-hydroxyproline, also known as 4-hydroxyproline, is a non-protein amino acid that plays a vital role in the structure and function of collagen, the most abundant protein in the human body. in recent years, researchers have been exploring the potential applications of l-hydroxyproline in drug discovery and development due to its unique properties and biological activity. first and foremost, it is. Group: Pharmaceutical. Alternative Names: trans-4-Hydroxy-L-proline; L-4-hydroxyproline; trans-4-Hydroxyproline; H-Hyp-OH; hydroxy-L-proline; 4-Hydroxy-L-proline; trans-L-Hydroxyproline; 4-Hydroxy-2-pyrrolidinecarboxylic acid. CAS No. 51-35-4. Pack Sizes: 1 kg. Product ID: BAT-014305. Molecular formula: C5H9NO3. Mole weight: 131.13. Custom synthesis is available. Send your inquiries for more information. | London |
| Mefloquine | Mefloquine is, a quinoline methanol phospholipid-interacting antimalarial drug, is very effective against sensitive malaria parasites with few side effects. Mefloquine may cause vomiting, especially in children. Uses: Treating or preventing malaria. Group: Pharmaceutical. Alternative Names: mefloquine;53230-10-7;(-)-Mefloquine;Mefloquin;Mefloquina;Mefloquinum;Mefloquinum [INN-Latin];Mefloquina [INN-Spanish];Ro 21-5998;(-)-(11S,2'R)-erythro-Mefloquine;Ro 215998;HSDB 6853;Racemic mefloquine;WR 142490;51742-87-1;UNII-TML814419R;TML814419R;(S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol;Mephloquine;CHEMBL172;(DL-erythro-alpha-2-Piperidyl-2,8-bis(trifluoromethyl). CAS No. 53230-10-7. Pack Sizes: 1mg;1g;10g. Product ID: 53230-10-7. Molecular formula: C26H27N5O2. Mole weight: 441.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Menaquinone 5 | Menaquinone 5 is a variant of Vitamin K2, orchestrating an indispensable role in the intertwining researchs of blood coagulation and skeletal robustness. Uses: Vitamin (prothrombogenic). Group: Pharmaceutical. Alternative Names: Menaguinone. CAS No. 1182-68-9. Pack Sizes: 5 mg. Product ID: B2694-120617. Molecular formula: C36H48O2. Mole weight: 512.77. Custom synthesis is available. Send your inquiries for more information. | London |
| Nitrocefin | Nitrocefin is a chromogenic cephalosporin substrate routinely used to detect the presence of beta-lactamase enzymes produced by various microbes. Group: Pharmaceutical. Alternative Names: 3-(2,4-Dinitrostyryl)-(6R,7R)-7-(2-thienylacetamido)-ceph-3-em-4-carboxylic acid; UNII-EWP54G0J8F; EWP54G0J8F. CAS No. 41906-86-9. Pack Sizes: 100 mg. Product ID: BBF-03759. Molecular formula: C21H16N4O8S2. Mole weight: 516.5. Custom synthesis is available. Send your inquiries for more information. | London |
| Stephanine | Stephanine is isolated from the root of Stephania japonica. It inhibits anococcygeus muscle contraction induced by phenylephrine, so Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker. Group: Pharmaceutical. Alternative Names: 8-Methoxy-1,2-methylenedioxyaporphine. CAS No. 517-63-5. Pack Sizes: 1 mg. Product ID: NP0452. Molecular formula: C19H19NO3. Mole weight: 309.4. Custom synthesis is available. Send your inquiries for more information. | London |
| T-5224 | T-5224 is a selective inhibitor of c-Fos/activator protein-1. T-5224 ameliorates liver injury and improves survival through decreasing production of proinflammatory cytokines and chemokines in endotoxemic mice. T-5224 has been investigated in phase II human clinical trials. T-5224 may be a promising new treatment for septic kidney injury. Activator protein 1 (AP-1) is a pivotal transcription factor that regulates a wide range of cellular processes including proliferation, apoptosis, differentiation, survival, cell migration, and transformation. Accumulating evidence supports that AP-1 plays an important role in several severe disorders including cancer, fibrosis, and organ injury, as well as inflammatory disorders such as asthma, psoriasis, and rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: T5224; T 5224. CAS No. 530141-72-1. Pack Sizes: 100 mg. Product ID: B1370-462792. Molecular formula: C29H27NO8. Mole weight: 517.53. Custom synthesis is available. Send your inquiries for more information. | London |
| Tebipenem Condensation Compound | Tebipenem Condensation Compound: Tebipenem, a potent carbapenem antibiotic, serves as a pivotal tool in combating a diverse range of bacterial infections through its mechanism of inhibiting cell wall biosynthesis. The condensation compound, a critical precursor in the intricate synthesis of tebipenem, plays a crucial role in advancing therapeutic strategies against resilient microbial adversaries. Group: Pharmaceutical. Alternative Names: 161715-20-4; 2-[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-1-methyl-6-[(4-nitrophenyl)methyl]-7-oxobicyclo[3.2.0]hept-2-ene-3-carboxylic acid4-Nitrobenzyl(1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-Methyl-2-[1-(1,3-thiazolin-2-yl)azetidin-3-yl]thio-1-carbapen-2-eM-3-carboxylateTebipenem Condensation Compound4-Nitrobenzyl(1R,5S,6S)-6-[(R)-1-hydroxyethyl]-1-Methyl-2-[1-(1,3-thiazolin-2-yl)azetidin -3-yl]thio-1-carbapen-2-eM-3-carboxylate. CAS No. 161715-20-4. Pack Sizes: 1mg;1g;10g. Product ID: 161715-20-4. Molecular formula: C24H26N3O6S2-. Mole weight: 516.60974. Custom synthesis is available. Send your inquiries for more information. | London |
| Tetrandrine | Tetrandrine is a bisbenylisoquinoline alkaloid isolated from the dried root of Stephenia tetrandra S Moore. Tetrandrine exhibits very broad pharmacological actions, including anti-tumor activity. The beneficial effects of tetrandrine on tumor cell cytotoxicity and radiosensitization, multidrug resistance, normal tissue radioprotection, and angiogenesis are most promising and deserve great attention. Tetrandrine has the potential either as a tumoricidal agent or as an adjunct to chemotherapy and radiotherapy. Uses: Nti-inflammatory, immunologic and antiallergenic. Group: Pharmaceutical. Alternative Names: Isotetrandrine; Tetrandrin; Fanchinine; (+)-Tetrandrine; Sinomenine A. CAS No. 518-34-3. Pack Sizes: 1 g. Product ID: NP0540. Molecular formula: C38H42N2O6. Mole weight: 622.762. Custom synthesis is available. Send your inquiries for more information. | London |
| Vemurafenib | Vemurafenib is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity than wild-type B-Raf. Group: Pharmaceutical. Alternative Names: PLX4032; PLX 4032; PLX-4032; RG7204 ; RG7204 ; RG 7204 ; RO5185426; RO 5185426 RO5185426 Vemurafenib; Brand name: Zelboraf. CAS No. 918504-65-1. Pack Sizes: 100 mg. Product ID: B0084-307764. Molecular formula: C23H18ClF2N3O3S. Mole weight: 489.92. Custom synthesis is available. Send your inquiries for more information. | London |
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