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| Product | Description | |
|---|---|---|
| 2-Deoxy-D-ribose | 25g Pack Size. Group: Sugars. Formula: C5H10O4. CAS No. 533-67-5. Prepack ID : 12691995-25g. Molecular Weight : 134.13. |  |
| 2-Deoxy-D-Ribose | 2-Deoxy-D-Ribose. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 533-67-5. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: thyminose. |  Cenik Chemicals |
| 2-Deoxy-L-ribose | 1g Pack Size. Group: Sugars. Formula: C5H10O4. CAS No. 18546-37-7. Prepack ID : 16224893-1g. Molecular Weight : 134.1. | |
| 5-Deoxy-D-ribose | 1g Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates, Diagnostic Raw Materials. Formula: C5H10O4. CAS No. 13039-75-3. Prepack ID : 90028732-1g. Molecular Weight : 134.13. | |
| 5-Deoxy-L-ribose phenylhydrazone | 5-Deoxy-L-ribose phenylhydrazone, an intriguing compound, has been the subject of numerous biomedical research studies, aimed at elucidating its impact on cellular metabolism, specifically glucose transport and metabolism. Additionally, this multifaceted compound has ignited significant interest due to its potential to treat diverse maladies, including cancer, owing to its tumor growth-inhibiting properties and apoptosis-inducing abilities. Group: Pharmaceutical. CAS No. 123168-30-9. Pack Sizes: 150 mg. Product ID: B1999-001003. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| D-Ribose | 100g Pack Size. Group: Sugars. Formula: C5H10O5. CAS No. 50-69-1. Prepack ID : 13992794-100g. Molecular Weight : 150.13. | |
| D-Ribose | 500g Pack Size. Group: Sugars. Formula: C5H10O5. CAS No. 50-69-1. Prepack ID : 13992794-500g. Molecular Weight : 150.13. | |
| D-Ribose-[1,2-13C2] | Labelled D-Ribose is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate. Group: Pharmaceutical. CAS No. 209909-88-6. Pack Sizes: 1 g. Product ID: BLP-009259. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| L-Ribose | 25g Pack Size. Group: Biochemicals, Carbohydrates. Formula: C5H10O5. CAS No. 24259-59-4. Prepack ID : 23543542-25g. Molecular Weight : 150.13. | |
| L-Ribose | 5g Pack Size. Group: Biochemicals, Carbohydrates. Formula: C5H10O5. CAS No. 24259-59-4. Prepack ID : 23543542-5g. Molecular Weight : 150.13. | |
| L-Ribose | L-Ribose. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 24259-59-4. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. | Cenik Chemicals |
| 5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite | 5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-Deoxy-guanosine 3'-CE phosphoramidite is a novel nucleoside analog for the incorporation of 2-fluoro-modified ribose-G nucleobases within oligonucleotides. Group: Pharmaceutical. CAS No. 144089-97-4. Pack Sizes: 5 g. Product ID: B2706-291975. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| AZ7371 | AZ7371 is a novel non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with IC50 of 10 nM. Group: Pharmaceutical. CAS No. 1494675-86-3. Pack Sizes: 50 mg. Product ID: B2693-470868. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| β-Nicotinamide Adenine Dinucleotide | NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It plays a role in the activity of several enzymes, such as poly(ADP)-ribose polymerases and cADP-ribose synthases. NAD+ is commonly used as an oxidizing agent. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. CAS No. 53-84-9. Pack Sizes: 10 g. Product ID: B0084-094034. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Icaritin | Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or ti | London |
| Olaparib | Olaparib, also known as AZD-2281 or KU-59436, is a small-molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Olaparib selectively binds to and inhibits PARP, inhibiting PARP-mediated repair of single strand DNA breaks; PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins and can be activated by single-stranded DNA breaks. Group: Pharmaceutical. CAS No. 763113-22-0. Pack Sizes: 1 g. Product ID: B0084-076683. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Pamiparib | Pamiparib is a potent and selective inhibitor of PARP1/PARP2 displaying anticancer activity. Uses: Poly(adp-ribose) polymerase inhibitors. Group: Pharmaceutical. CAS No. 1446261-44-4. Pack Sizes: 50 mg. Product ID: B2693-291315. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| PseudoUridine 5'-monophosphate Sodium salt | A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Group: Pharmaceutical. Pack Sizes: 100 mg. Product ID: B1370-285301. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rucaparib | Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway. So, rucaparib has been also found to be most effective in cells deficient in DNA repair, where the cells deficient are caused by exposure to genotoxic agents, such as irradiation produces DNA damage and its toxicity is augmented when the DNA repair is impaired. Increased radiosensitivity in presence of rucaparib was associated with persistent DNA breaks as determined by gamma-H2AX and p53BP1 foci. Rucaparib radiosensitizes prostate cancer cells, most effectively those that are PTEN-deficient and are expressing ETS gene fusion proteins, which inhibits NHEJ DNA repair. Uses: Cancer therapy. Group: Pharmaceutical. CAS No. 283173-50-2. Pack Sizes: 250 mg. Product ID: B2693-104639. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Rucaparib monocamsylate | Rucaparib camsylate is an inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, which work in DNA repair process. It was approved for the treatment of ovarian cancer, and Rubraca is proved to be a monotherapy for the patients deleterious BRCA mutation associated advanced ovarian cancer who were treated with two or more chemotherapies. Group: Pharmaceutical. CAS No. 1859053-21-6. Pack Sizes: 100 mg. Product ID: B0084-007117. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Talazoparib | Talazoparib, also known as BMN-673, is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development. Uses: For research used only. Group: Pharmaceutical. CAS No. 1207456-01-6. Pack Sizes: 100 mg. Product ID: B0084-462689. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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