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25g Pack Size. Group: Sugars. Formula: C5H10O4. CAS No. 533-67-5. Prepack ID : 12691995-25g. Molecular Weight : 134.13.
2-Deoxy-D-Ribose
2-Deoxy-D-Ribose. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 533-67-5. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. Categories: thyminose.
Cenik Chemicals
2-Deoxy-L-ribose
1g Pack Size. Group: Sugars. Formula: C5H10O4. CAS No. 18546-37-7. Prepack ID : 16224893-1g. Molecular Weight : 134.1.
5-Deoxy-D-ribose
1g Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates, Diagnostic Raw Materials. Formula: C5H10O4. CAS No. 13039-75-3. Prepack ID : 90028732-1g. Molecular Weight : 134.13.
5-Deoxy-L-ribose phenylhydrazone
5-Deoxy-L-ribose phenylhydrazone, an intriguing compound, has been the subject of numerous biomedical research studies, aimed at elucidating its impact on cellular metabolism, specifically glucose transport and metabolism. Additionally, this multifaceted compound has ignited significant interest due to its potential to treat diverse maladies, including cancer, owing to its tumor growth-inhibiting properties and apoptosis-inducing abilities. Group: Pharmaceutical. Alternative Names: L-Ribose, 5-deoxy-, phenylhydrazone. CAS No. 123168-30-9. Pack Sizes: 150 mg. Product ID: B1999-001003. Molecular formula: C11H16N2O3. Mole weight: 224.26. Custom synthesis is available. Send your inquiries for more information.
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D-Ribose
100g Pack Size. Group: Sugars. Formula: C5H10O5. CAS No. 50-69-1. Prepack ID : 13992794-100g. Molecular Weight : 150.13.
D-Ribose
500g Pack Size. Group: Sugars. Formula: C5H10O5. CAS No. 50-69-1. Prepack ID : 13992794-500g. Molecular Weight : 150.13.
D-Ribose-[1,2-13C2]
Labelled D-Ribose is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate. Group: Pharmaceutical. Alternative Names: Ribose-1,2-13C2; D-(-)-Ribose-1,2-13C2. CAS No. 209909-88-6. Pack Sizes: 1 g. Product ID: BLP-009259. Molecular formula: C3[13C]2H10O5. Mole weight: 152.12. Custom synthesis is available. Send your inquiries for more information.
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L-Ribose
25g Pack Size. Group: Biochemicals, Carbohydrates. Formula: C5H10O5. CAS No. 24259-59-4. Prepack ID : 23543542-25g. Molecular Weight : 150.13.
L-Ribose
5g Pack Size. Group: Biochemicals, Carbohydrates. Formula: C5H10O5. CAS No. 24259-59-4. Prepack ID : 23543542-5g. Molecular Weight : 150.13.
L-Ribose
L-Ribose. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 24259-59-4. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications.
2-Aminoadenosine-5'-Triphosphate, a versatile compound, finds extensive applications in enzymology and biotechnology as a substrate for kinases, ATPases, and nucleotide pyrophosphatases. Additionally, it is noteworthy for its ability to stimulate bone resorption activity in separated osteoclasts, therefore facilitating the study of bone metabolism and related diseases like osteoporosis and osteopenia. Group: Pharmaceutical. Alternative Names: 2-Amino-adenosine-5'-triphosphate; 2-NH2-ATP; 2-Amino-ATP; 2,6-Diaminopurine-ribose-5'-Triphosphate; DAP-rTP; 2-Aminoadenosine 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); 9H-Purine, 2,6-diamino-9-β-D-ribofuranosyl-, 5'-triphosphate; 2,6-Diaminopurine ribonucleoside triphosphate; 2,6-Diaminopurine riboside 5'-triphosphate; 2,6-Diaminopurine riboside triphosphate; 2,6-Diaminopurineribosyl-5'-triphosphate. CAS No. 18549-34-3. Pack Sizes: 1 mL. Product ID: B1370-362752. Molecular formula: C10H17N6O13P3. Mole weight: 522.2. Custom synthesis is available. Send your inquiries for more information.
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2'-O-Methyladenosine
2'-O-Methyladenosine is a modified nucleoside where a methyl group is attached to the 2' hydroxyl of the ribose sugar. This modification enhances the stability and binding affinity of RNA molecules, making it valuable in research focused on RNA structure, function, and therapeutic development. It is commonly used in the synthesis of chemically modified RNA for studies in molecular biology and biotechnology. Group: Pharmaceutical. Alternative Names: Adenosine, 2'-O-methyl-; (2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; Cordysinin B; 2'-O-Methyl-D-adenosine; 2'-O-Me-adenosine; 2'-(O-Methyl) Adenosine; 2'-O-Me-Ado. CAS No. 2140-79-6. Pack Sizes: 25 g. Product ID: B1370-336353. Molecular formula: C11H15N5O4. Mole weight: 281.27. Custom synthesis is available. Send your inquiries for more information.
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7-Methyl-3'-O-methylguanosine 5'-(trihydrogen diphosphate), inner salt, TEA salt
7-Methyl-3'-O-methylguanosine 5'-(trihydrogen diphosphate), inner salt, TEA salt is a modified nucleoside used in research. It consists of guanosine with methyl groups at the 7th position of the base and the 3' carbon of the ribose sugar. It has a diphosphate group at the 5' carbon of the ribose with three hydrogen atoms bound to the phosphates. It is commonly employed in biochemical studies, especially in RNA research. Group: Pharmaceutical. Alternative Names: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-3'-O-methyl-, inner salt, compd. with N,N-diethylethanamine (1:x); Triethylamine ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-3,6-dihydro-9H-purin-7-ium-9-yl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)methyl diphosphate (1:x); 3'-OMe-m7GDP TEA Salt; Guanosine 5'-(trihydrogen diphosphate), 7-Methyl-3'-O-Methyl-, inner Salt, compd. with N,N-diethylethanamine. CAS No. 2089461-52-7. Pack Sizes: 100 mg. Product ID: B1370-088411. Molecular formula: C12H19N5O11P2.xC6H15N. Mole weight: 471.26 (free base). Custom synthesis is available. Send your inquiries for more information.
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8-Azanebularine CE-Phosphoramidite
DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite is a chemical compound used in oligonucleotide synthesis. It protects the 5'-hydroxyl group with a DMTr group and stabilizes the ribose sugar with a 2'-O-TBDMS modification. Additionally, it incorporates 8-azanebularine as a modified nucleoside. The 3'-CE phosphoramidite facilitates nucleotide addition during synthesis. This compound allows for the controlled synthesis of oligonucleotides with specific modifications, important for various applications in molecular biology and biotechnology. Group: Pharmaceutical. Alternative Names: DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite. CAS No. 771494-03-2. Pack Sizes: 50 mg. Product ID: B1370-087581. Molecular formula: C45H60N7O7PSi. Mole weight: 870.08. Custom synthesis is available. Send your inquiries for more information.
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AZ7371
AZ7371 is a novel non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with IC50 of 10 nM. Group: Pharmaceutical. Alternative Names: AZ-7371; AZ 7371; TBA-7371; DprE1-IN-1. CAS No. 1494675-86-3. Pack Sizes: 50 mg. Product ID: B2693-470868. Molecular formula: C18H21N5O3. Mole weight: 355.4. Custom synthesis is available. Send your inquiries for more information.
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β-Nicotinamide Adenine Dinucleotide
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It plays a role in the activity of several enzymes, such as poly(ADP)-ribose polymerases and cADP-ribose synthases. NAD+ is commonly used as an oxidizing agent. Nutritional supplement in health care products. Uses: Ingredient of health care products. Group: Pharmaceutical. Alternative Names: Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium, inner salt; Nadide; Coenzyme I; Beta-NAD; Diphosphopyridine nucleotide; NAD+; Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-(aminocarbonyl)-1-β-D-ribofuranosylpyridinium hydroxide, inner salt; Adenine-nicotinamide dinucleotide; CO-I; Codehydrase I; Codehydrogenase I; Cozymase I; DPN; Enzopride; NAD; Nicotinamide-adenine dinucleotide; NSC 20272; Oxidized diphosphopyridine nucleotide; β-Diphosphopyridine nucleotide; β-NAD; β-NAD+. CAS No. 53-84-9. Pack Sizes: 10 g. Product ID: B0084-094034. Molecular formula: C21H27N7O14P2. Mole weight: 663.43. Custom synthesis is available. Send your inquiries for more information.
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dSpacer-CEP
dSpacer is used to introduce stable abasic sites in oligonucleotides. Group: Pharmaceutical. Alternative Names: 5'-O-(4,4'-Dimethoxytrityl)-1',2'-dideoxyribose-3'-O-[(2-cyanoethyl)-(N,N-Diisopropyl)]-phosphoramidite; 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite; dSpacer CE Phosphoramidite; (2R,3S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; D-erythro-Pentitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. CAS No. 129821-76-7. Pack Sizes: 100 mg. Product ID: B2705-072846. Molecular formula: C35H45N2O6P. Mole weight: 620.71. Custom synthesis is available. Send your inquiries for more information.
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Icaritin
Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or ti
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Nicotinamide riboside
Nicotinamide riboside is a form of pyridine nucleoside with a nicotinamide. It is a precursor to NAD+ and a source of vitamin B3. Nicotinamide riboside increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells. It also activates SIRT1 and SIRT3 in vitro. Group: Pharmaceutical. Alternative Names: Nicotinamide-beta-riboside; Nicotinamide ribonucleoside; N-Ribosylnicotinamide; 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium; Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-; 3-Pyridinecarboxamide, 1-β-D-ribosyl-; Nicotinamide ribose; Ribosylnicotinamide. CAS No. 1341-23-7. Pack Sizes: 5 g. Product ID: B0001-394639. Molecular formula: C11H15N2O5. Mole weight: 255.25. Custom synthesis is available. Send your inquiries for more information.
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Olaparib
Olaparib, also known as AZD-2281 or KU-59436, is a small-molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing, and antineoplastic activities. Olaparib selectively binds to and inhibits PARP, inhibiting PARP-mediated repair of single strand DNA breaks; PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins and can be activated by single-stranded DNA breaks. Group: Pharmaceutical. Alternative Names: AZD2281; AZD-2281; AZD 2281; KU59436; KU-59436; KU 59436; KU0059436; KU-0059436; KU 0059436; Olaparib. trade name Lynparza; 4-[[3-[4-(cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one. CAS No. 763113-22-0. Pack Sizes: 1 g. Product ID: B0084-076683. Molecular formula: C24H23FN4O3. Mole weight: 434.471. Custom synthesis is available. Send your inquiries for more information.
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Pamiparib
Pamiparib is a potent and selective inhibitor of PARP1/PARP2 displaying anticancer activity. Uses: Poly(adp-ribose) polymerase inhibitors. Group: Pharmaceutical. Alternative Names: BGB-290. CAS No. 1446261-44-4. Pack Sizes: 50 mg. Product ID: B2693-291315. Molecular formula: C16H15FN4O. Mole weight: 298.31. Custom synthesis is available. Send your inquiries for more information.
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PseudoUridine 5'-monophosphate Sodium salt
A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Group: Pharmaceutical. Alternative Names: Pseudouridylic acid sodium salt; (1S)-1,4-anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5-O-phosphono-D-ribitol sodium salt; pseudouridine 5'-phosphate sodium salt; 5-(5-O-phosphono-beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione sodium salt; 5-b-D-Ribofuranosyluracil 5'-phosphate sodium salt; Uracil, 5-b-D-ribofuranosyl-, 5'-phosphate, sodium salt; pUMP Sodium Salt. Pack Sizes: 100 mg. Product ID: B1370-285301. Molecular formula: C9H13N2O9P.xNa. Mole weight: 324.18 (free acid). Custom synthesis is available. Send your inquiries for more information.
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Ribitol-[13C5]
Labelled D-Ribitol is used in the preparation of L-ribose and and arabinose, as well as a diagnostic tool for identifying human bladder cancer (HBC) through noninvasive urinary metabonomics. Group: Pharmaceutical. Alternative Names: [UL-13C5]ribitol; [UL-13C5]adonitol; ribitol-U-13C5; Adonitol-1,2,3,4,5-13C5. Pack Sizes: 100 mg. Product ID: BLP-013244. Molecular formula: [13C]5H12O5. Mole weight: 157.11. Custom synthesis is available. Send your inquiries for more information.
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Rucaparib
Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway. So, rucaparib has been also found to be most effective in cells deficient in DNA repair, where the cells deficient are caused by exposure to genotoxic agents, such as irradiation produces DNA damage and its toxicity is augmented when the DNA repair is impaired. Increased radiosensitivity in presence of rucaparib was associated with persistent DNA breaks as determined by gamma-H2AX and p53BP1 foci. Rucaparib radiosensitizes prostate cancer cells, most effectively those that are PTEN-deficient and are expressing ETS gene fusion proteins, which inhibits NHEJ DNA repair. Uses: Cancer therapy. Group: Pharmaceutical. Alternative Names: 8-Fluoro-2-(4-((methylamino)methyl)phenyl)-1,3,4,5-tetrahydro-6H-azepino(5,4,3-cd)indol-6-one; Rucaparib free base, AG-14447; AG 14447; AG14447; Rubraca. CAS No. 283173-50-2. Pack Sizes: 250 mg. Product ID: B2693-104639. Molecular formula: C19H18FN3O. Mole weight: 323.36. Custom synthesis is available. Send your inquiries for more information.
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Rucaparib monocamsylate
Rucaparib camsylate is an inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, which work in DNA repair process. It was approved for the treatment of ovarian cancer, and Rubraca is proved to be a monotherapy for the patients deleterious BRCA mutation associated advanced ovarian cancer who were treated with two or more chemotherapies. Group: Pharmaceutical. Alternative Names: Rucaparib camsylate; Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1S,4R)-, compd. with 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one (1:1); 8-fluoro-5-(4-((methylamino)methyl)phenyl)-2,3,4,6-tetrahydro-1H-azepino[5,4,3-cd]indol-1-one ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate (1:1); 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2,ef][2]benzazepin-6-one (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid (1:1). CAS No. 1859053-21-6. Pack Sizes: 100 mg. Product ID: B0084-007117. Molecular formula: C29H34FN3O5S. Mole weight: 555.66. Custom synthesis is available. Send your inquiries for more information.
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Talazoparib
Talazoparib, also known as BMN-673, is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development. Uses: For research used only. Group: Pharmaceutical. Alternative Names: BMN-673; LT-673. BMN 673; LT 673. BMN673; LT673. CAS No. 1207456-01-6. Pack Sizes: 100 mg. Product ID: B0084-462689. Molecular formula: C19H14F2N6O. Mole weight: 380.359. Custom synthesis is available. Send your inquiries for more information.
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Tetramethyl methylenediphosphonate
Tetramethyl methylenediphosphonate (TMP) is used in the preparation of phosphonate analogue of ribose-1-phosphate. Group: Pharmaceutical. Alternative Names: Tetramethyl methylenebis(phosphonate); Phosphonic acid, methylenebis-, tetramethyl ester; Methylenediphosphonic acid tetramethyl ester. CAS No. 16001-93-7. Pack Sizes: 100 g. Product ID: B1370-192089. Molecular formula: C5H14O6P2. Mole weight: 232.11. Custom synthesis is available. Send your inquiries for more information.
1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt) is a liposome formulation for cationic lipid DOTAP. DOTAP can be used for the efficiency of DNA transfection, including yeast artificial chromosomes (YAC) transfection to eukaryotic cells used in transient or stable gene expression, and also suitable for efficient will other negatively charged molecules, such as RNA, oligonucleotides, and glutamic acid, the ribosome protein (RNP) complex, and protein, transferred to the study sample of mammalian cells. Group: Pharmaceutical. Alternative Names: DOTAP Transfection Reagent; DOTAP-MS; N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate; DOTAP methosulfate; 18:1 TAP (DOTAP, MS Salt); n-(2,3-dioleoyloxy-1-propyl) trimethylammonium methyl sulfate. CAS No. 144189-73-1. Pack Sizes: 500 mg. Product ID: BAT-006359. Molecular formula: C43H83NO8S. Mole weight: 774.19. Custom synthesis is available. Send your inquiries for more information.
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1,2-O-Isopropylidene-alpha-D-xylofuranose
1,2-O-Isopropylidene-alpha-D-xylofuranose is an intermediate used in the synthesis of C-glycosides ribosyl-acid and ribosyl-aldehyde. Group: Pharmaceutical. Alternative Names: 1,2-O-(1-methylethylidene)-α-D-xylofuranose; 1,2-Di-O-isopropylidene-α-D-xylofuranose; 1,2-O-Isopropylidene-D-xylofuranose. CAS No. 20031-21-4. Pack Sizes: 50 g. Product ID: B2705-365935. Molecular formula: C8H14O5. Mole weight: 190.19. Custom synthesis is available. Send your inquiries for more information.
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1-MethylpseudoUridine
N1-methyl-pseudoUridine (1-Methylpseudouridine), a methylpseudoUridine, outperforms 5 mC and 5 mC/N1-methyl-pseudoUridine in translation. N1-methyl-pseudoUridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density. Group: Pharmaceutical. Alternative Names: N1-Methylpseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-b-D-ribofuranosyl-; (-)-1-Methyl-5-(β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; Antibiotic U-50228; U-50228; 1-N-Me-pseudouridine; (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol; Uracil, 1-methyl-5-b-D-ribofuranosyl-. CAS No. 13860-38-3. Pack Sizes: 1 g. Product ID: B2706-207673. Molecular formula: C10H14N2O6. Mole weight: 258.23. Custom synthesis is available. Send your inquiries for more information.
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2-Amino-3'-O-methyladenosine
2-Amino-3'-O-methyladenosine, a versatile biomolecule, exhibits promising therapeutic potential in tackling a myriad of pathological conditions, ranging from malignant neoplasms to infectious disorders and inflammatory ailments, and has garnered immense attention as a vital investigative probe for exploring the intricate roles of RNA methylation. Emerging evidence points to the multifaceted role of 2-Amino-3'-O-methyladenosine in impeding tumorigenesis, abating viral propagation, and modulating immune reactivity, thus underscoring its indispensable relevance in the biomedical arena. Group: Pharmaceutical. Alternative Names: (2R,3R,4S,5R)-2-(2,6-diamino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; Adenosine, 2-amino-3'-O-methyl-; 2,6-Diaminopurine-3'-O-methyl-riboside; 3'-OMe-2-NH2-A. CAS No. 80791-88-4. Pack Sizes: 100 mg. Product ID: B2706-043240. Molecular formula: C11H16N6O4. Mole weight: 296.28. Custom synthesis is available. Send your inquiries for more information.
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2-Amino-6-chloropurine-9-(2'-O-methyl)riboside
2-Amino-6-chloropurine-9-(2'-O-methyl)riboside is a remarkable biomedical entity, diligently confronting the pernicious wrath of herpes simplex virus and varicella-zoster virus, rendering them futile through the inhibition of viral DNA synthesis and replication. Group: Pharmaceutical. Alternative Names: 6-Chloro-2'-O-methylguanosine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 2-Amino-6-chloro-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 6-Chloro-9-(2-O-methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2'-O-Methyl-2-amino-6-chloropurine riboside. CAS No. 194034-59-8. Pack Sizes: 25 mg. Product ID: B2706-047011. Molecular formula: C11H14ClN5O4. Mole weight: 315.71. Custom synthesis is available. Send your inquiries for more information.
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2-Methylthio-N6-iso-pentenyladenosine
2-Methylthio-N6-isopentenyladenosine is located at position 37 in tRNAs that read codons starting with uridine. 2-Methylthio-N6-isopentenyladenosine in trpT(Su9) suppressor tRNA increase the efficiency of the tRNA by protecting it from ribosomal proofreading which is induced by codon context. Group: Pharmaceutical. Alternative Names: Adenosine, N-(3-methyl-2-butenyl)-2-(methylthio)-; 2-Methyl-thio-N6-isopentyladenosine; N6-Isopentenyl-2-thiomethyladenosine; N-(3-Methyl-2-buten-1-yl)-2-(methylsulfanyl)adenosine; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methylbut-2-en-1-yl)amino)-2-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol. CAS No. 20859-00-1. Pack Sizes: 1 mg. Product ID: B1370-337320. Molecular formula: C16H23N5O4S. Mole weight: 381.45. Custom synthesis is available. Send your inquiries for more information.
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6-Chloropurine-9-riboside
1g Pack Size. Group: Building Blocks, Carbohydrates. Formula: C10H11ClN4O4. CAS No. 2004-06-0. Prepack ID : 66096478-1g. Molecular Weight : 286.68.
6-Methylpurine 2'-deoxyriboside
It's a prodrug of the anticancer agent 6-methylpurine, and it is used in gene therapy. Group: Pharmaceutical. Alternative Names: 6-Methylpurine-2'-deoxy-beta-D-riboside; MePdR; 9-(2-Deoxy-β-D-erythropentofuranosyl)-6-methyl-9H-purine; (2R,3S,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3-ol; NSC 103543; 9-(2-Deoxy-beta-D-ribofuranosyl)-6-methyl-9H-purine. CAS No. 16006-64-7. Pack Sizes: 5 mg. Product ID: B2000-235512. Molecular formula: C11H14N4O3. Mole weight: 250.25. Custom synthesis is available. Send your inquiries for more information.
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6-Thioguanosine
6-Thioguanosine is a significant nucleoside analog employed in the biomedical industry, holding an eminent role in comprehending the intricate ramifications of DNA methylation on gene expression. Group: Pharmaceutical. Alternative Names: 2-Amino-6-mercapto-9-(b-D-ribofuranosyl)purine; 6-Mercaptoguanosine; (-)-2-Amino-6-mercaptopurine riboside. CAS No. 85-31-4. Pack Sizes: 1 g. Product ID: B2706-078431. Molecular formula: C10H13N5O4S. Mole weight: 299.31. Custom synthesis is available. Send your inquiries for more information.
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(9S)-9-Deoxo-12-deoxy-9,12-epoxyerythromycin
(9S)-9-Deoxo-12-deoxy-9,12-epoxyerythromycin is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Group: Pharmaceutical. Alternative Names: Erythromycin, 9-deoxo-12-deoxy-9,12-epoxy-, (9S)-; (1S,2R,5R,6S,7S,8R,9R,11R,12S,13R,14R)-8-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-9,14-dihydroxy-6-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-1,5,7,9,11,13-hexamethyl-3,15-dioxabicyclo[10.2.1]pentadecan-4-one; A 69328. CAS No. 134108-11-5. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04137. Molecular formula: C37H67NO12. Mole weight: 717.93. Custom synthesis is available. Send your inquiries for more information.
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Avilamycin A
Avilamycin A is produced by the strain of Streptomyces viridochromogenes NRRL 2860. It inhibits the binding of amino acid-based tRNA to the bacterial ribosome for 30S subunit and has anti-gram-positive bacterial activity. It has been tried as feed additive in animal feeding. Group: Pharmaceutical. Alternative Names: Flambamycin, 23-deoxy-. CAS No. 69787-79-7. Pack Sizes: 1mg;1g;10g. Product ID: BBF-00233. Molecular formula: C61H88Cl2O32. Mole weight: 1404.23. Custom synthesis is available. Send your inquiries for more information.
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Azithromycin EP Impurity B
An impurity of Azithromycin. Azithromycin B is a macrolide antibiotic that is structurally related to erythromycin and contains a 15-membered ring. It is known for its broad-spectrum activity against a variety of bacterial infections. Azithromycin works by binding to the 50S ribosomal subunit of bacteria, which inhibits their protein synthesis. This medication is used to treat several types of infections, including respiratory, enteric, and genitourinary infections, as well as some sexually transmitted diseases. Group: Pharmaceutical. Alternative Names: Azithromycin B; 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-4,10-dihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3R,4R,5R,8R,10R,11R,12R,13S,14R)-; 3-Deoxyazithromycin; Azithromycin Impurity B. CAS No. 307974-61-4. Pack Sizes: 1 mg. Product ID: B0051-467176. Molecular formula: C38H72N2O11. Mole weight: 733. Custom synthesis is available. Send your inquiries for more information.
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beta-Nicotinamide adenine dinucleotide phosphate
NADP zwitterion is a NADP. It has a role as a fundamental metabolite. It is a conjugate base of a NADP(+). A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). Group: Pharmaceutical. Alternative Names: beta-NADP; NADP; TPN; Triphosphopyridine nucleotide; coenzyme II; Codehydrogenase II; Nadide phosphate. CAS No. 53-59-8. Pack Sizes: 50 g. Product ID: B1370-093984. Molecular formula: C21H28N7O17P3. Mole weight: 743.41. Custom synthesis is available. Send your inquiries for more information.
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β-pseudoUridine
An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that Beta-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes. Group: Pharmaceutical. Alternative Names: Pseudouridine; ψ-Uridine; 5-(β-D-Ribofuranosyl)uracil; b-pseudoUridine; 5-β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione; 5-Ribosyluracil; NSC 162405; Pseudouridine C; β-D-Pseudouridine; pseudo-Uridine; Pseudouracil; Pseudouridine; β-Pseudouridine; 5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 1445-07-4. Pack Sizes: 5 g. Product ID: BBF-04654. Molecular formula: C9H12N2O6. Mole weight: 244.2. Custom synthesis is available. Send your inquiries for more information.
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Blasticidin S Hydrochloride
Blasticidin S HCl is a nucleoside antibiotic that is first isolated from Streptomyces griseochromogenes. Blasticidin S inhibits protein synthesis in both prokaryotic and eukaryotic cells via suppressing peptide bond formation by the ribosome. Uses: Antibiotic that inhibits protein synthesis. Group: Pharmaceutical. Alternative Names: (S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid hydrochloride; 4-Phenyl-3-propan-2-ylhept-1-en-5-yn-4-ol. CAS No. 3513-3-9. Pack Sizes: 1mg;1g;10g. Product ID: BBF-04056. Molecular formula: C17H26N8O5.HCl. Mole weight: 458.9. Custom synthesis is available. Send your inquiries for more information.
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Clarithromycin
It is produced by the strain of erythromycin. Clarithromycin, a CYP3A4 inhibitor, is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia, skin and skin structure infections. It prevents bacteria from growing by interfering with their protein synthesis and binds to the subunit 50S of the bacterial ribosome and thus inhibits the translation of peptides. It has similar antimicrobial spectrum as erythromycin, but is more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. It also has bactericidal effect on certain strains, such as Haemophilus influenzae, Streptococcus pneumoniae and Neisseria gonorrhoeae. Uses: Anti-bacterial agents. Group: Pharmaceutical. Alternative Names: Biaxin; 6-O-Methylerythromycin; Klaricid; Abbott-56268; 6-O-Methylerythromycin A; A 56268; Abbott 56268; Antibiotic A 56268; Antibiotic TE 31; Clamicin; Claric; Claridar; Claris; Claritek; Clarith; Clarithro; Clathromycin; Crixan; CRIXAN OD; Fascar; Fromilid; Kelamycin; Klabax; Klacid; Klaribac; Klarimix; Klarithran MR; Macladin; Naxy; TE 031; Veclam; Zeclar. CAS No. 81103-11-9. Pack Sizes: 1mg;1g;10g. Product ID: BBF-00648. Molecular formula: C38H69NO13. Mole weight: 747.95. Custom synthesis is available. Send your inquiries for more information.
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Demeclocycline
It is produced by the strain of Streptomuces aureofaciens var. 38-2-14. It shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Group: Pharmaceutical. Alternative Names: Demethylchlortetracycline; 6-Demethylchlotetracycline; DMCT; 7-Chloro-6-demethyltetracycline; Ledermycin; RP 10192; Antibiotic 38-2-14 A; Novotriclina; Perciclina; Sumaclina. CAS No. 127-33-3. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03477. Molecular formula: C21H21ClN2O8. Mole weight: 464.85. Custom synthesis is available. Send your inquiries for more information.
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Doxycycline hydrochloride
It is produced by the strain of Oxytetracycline or Methacycline. It is regarded as the third generation of tetracycline. It shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Its antibacterial spectrum is similar to Tetracycline, its antibacterial activity is 2-8 times of Tetracycline, its plasma elimination half-life is as long as 18-22h, and it has little effect on renal function. It can be used for the prevention and treatment of domestic animal respiratory diseases and mixed infection of bacterial diseases when respiratory diseases occur. Uses: Anti-bacterial agents. Group: Pharmaceutical. Alternative Names: Doxylin; samecin; 6-deoxy-5-oxytetracycline hydrochloride; novadox; liomycin; retens; Doxycycline HCl; tecacin; mespafin; Doxigalumicina; Doxylin; Deoxy-5-hydroxytetracycline hydrochloride. CAS No. 10592-13-9. Pack Sizes: 1mg;1g;10g. Product ID: BBF-01769. Molecular formula: C22H25ClN2O8. Mole weight: 480.89. Custom synthesis is available. Send your inquiries for more information.
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Erythromycin A iminoether
An impurity of Azithromycin. Azithromycin, derived from erythromycin, is an antibiotic. It binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. It is an azalide, a subclass of macrolide antibiotics and is one of the world's best-selling antibiotics. Group: Pharmaceutical. Alternative Names: Erythromycin A 9,11-Imino Ether. CAS No. 161193-44-8. Pack Sizes: 100 mg. Product ID: B0864-471157. Molecular formula: C37H66N2O12. Mole weight: 730.94. Custom synthesis is available. Send your inquiries for more information.
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Erythromycin EP Impurity A
An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 58S ribosomal subunit, blocking the progression of nascent polypeptide chains. Group: Pharmaceutical. Alternative Names: Erythromycin F; 16-Hydroxyerythromycin; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3-(hydroxymethyl)-5,7,9,11,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione. CAS No. 82230-93-1. Pack Sizes: 10 mg. Product ID: B1370-174079. Molecular formula: C37H67NO14. Mole weight: 749.93. Custom synthesis is available. Send your inquiries for more information.
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Erythromycin EP Impurity B
A metabolite of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. Group: Pharmaceutical. Alternative Names: N-Demethylerythromycin A; N-Desmethyl Erythromycin A; Des-N-methylerythromycin; Demethylerythromycin; USP Erythromycin Related Compound N; 3'-Demethylerythromyon; 11,13-hexamethyl-oxacyclotetradecane-2,10-dione. CAS No. 992-62-1. Pack Sizes: 25 mg. Product ID: BBF-04556. Molecular formula: C36H65NO13. Mole weight: 719.9. Custom synthesis is available. Send your inquiries for more information.
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Erythromycin EP Impurity C
An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 61S ribosomal subunit, blocking the progression of nascent polypeptide chains. Group: Pharmaceutical. Alternative Names: 1'',16-epoxy-Erythromycin; erythromycin E. CAS No. 41451-91-6. Pack Sizes: 10 mg. Product ID: B1370-117095. Molecular formula: C37H65NO14. Mole weight: 747.91. Custom synthesis is available. Send your inquiries for more information.
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Erythromycin EP Impurity D
An acid-catalyzed degradation product of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 57S ribosomal subunit, blocking the progression of nascent polypeptide chains. Group: Pharmaceutical. Alternative Names: Anhydroerythromycin A; Anhydro Erythromycin A; 9-Deoxo-6,12-dideoxy-6,9:9,12-diepoxy-erythromycin; 6,9,12-Anhydroerythromycin A. CAS No. 23893-13-2. Pack Sizes: 25 mg. Product ID: BBF-04426. Molecular formula: C37H65NO12. Mole weight: 715.91. Custom synthesis is available. Send your inquiries for more information.
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Erythromycin EP Impurity N
An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 56S ribosomal subunit, blocking the progression of nascent polypeptide chains. Group: Pharmaceutical. Alternative Names: (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-14-ethyl-4,6,7,12-tetrahydroxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione; Erythronolide B. CAS No. 3225-82-9. Pack Sizes: 1 mg. Product ID: B2694-471158. Molecular formula: C21H38O7. Mole weight: 402.52. Custom synthesis is available. Send your inquiries for more information.
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Erythromycin ethylsuccinate
Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis. Group: Pharmaceutical. Alternative Names: Pediamycin; EryPed; Wyamycin E; Erythromycin ethyl succinate; Erythromycin, 2'-(ethyl butanedioate); Erythroped; Erythromycin A Ethylsuccinate; (2S,3R,4S,6R)-4-(Dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl succinate; Erythromycin, mono(ethyl succinate) (ester); Succinic acid, ethyl ester, monoester with erythromycin; Anamycin; Arpimycin; Durapaediat; Monomycin; Paediathrocin; Refkas; Sigapedil. CAS No. 1264-62-6. Pack Sizes: 1mg;1g;10g. Product ID: BBF-03813. Molecular formula: C43H75NO16. Mole weight: 862.05. Custom synthesis is available. Send your inquiries for more information.
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FMK
FMK is a potent, highly specific and irreversible ribosomal s6 kinase (RSK) inhibitor that covalently modifies the C-terminal kinase domain of RSK. Its IC50 value is 15 nM. It could prevent the activation of the N-terminal kinase domain of RSK by the C-terminal kinase domain, but does not affect the activity of the N-terminal domain. It binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. It induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells. It is used to determine the role of RSK as a direct regulator of NHE1 phosphorylation and sarcolemmal NHE activity in this cell type, in response to 1-adrenergic stimulation. Uses: Fmk could prevent the activation of the n-terminal kinase domain of rsk by the c-terminal kinase domain, but does not affect the activity of the n-terminal domain. it is used to determine the role of rsk as a direct regulator of nhe1 phosphorylation and sarcolemmal nhe activity in this cell type, in response to 1-adrenergic stimulation. Group: Pharmaceutical. Alternative Names: 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone;RSK2 kinase inhibitor. CAS No. 821794-92-7. Pack Sizes: 10 mg. Product ID: B0084-455721. Molecular formula: C18H19FN4O2. Mole weight: 342.37. Custom synthesis is available. Send your inquiries for more information.
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Golgicide A
Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1. Golgicide A inhibited HSV-1 entry via beta-galactosidase reporter assay and impaired incoming virus transport to the nuclear periphery. Group: Pharmaceutical. Alternative Names: GCA; (3aR,9bS)-rel-6,8-Difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-3H-cyclopenta[c]quinoline; 3H-Cyclopenta[c]quinoline, 6,8-difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-, (3aR,9bS)-. CAS No. 1139889-93-2. Pack Sizes: 100 mg. Product ID: B1370-261662. Molecular formula: C17H14F2N2. Mole weight: 284.3. Custom synthesis is available. Send your inquiries for more information.
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Humanin (human) (trifluoroacetate salt)
Humanin is a micropeptide encoded by the 16S ribosomal RNA gene MT-RNR2 in the mitochondrial genome. Group: Pharmaceutical. Alternative Names: H-Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH.TFA; L-methionyl-L-alanyl-L-prolyl-L-arginyl-glycyl-L-phenylalanyl-L-seryl-L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-alpha-aspartyl-L-leucyl-L-prolyl-L-valyl-L-lysyl-L-arginyl-L-arginyl-L-alanine trifluoroacetic acid. Pack Sizes: 25 mg. Product ID: BAT-017108. Molecular formula: C121H205F3N34O34S2. Mole weight: 2801.3. Custom synthesis is available. Send your inquiries for more information.
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Isepamicin Sulphate
Isepamicin Sulphate, an aminoglycoside antibiotic, inhibits bacterial protein synthesis by targeting the bacterial 30S ribosomal subunit. Group: Pharmaceutical. Alternative Names: isepamicin sulfate; Isepamicin monosulfate. CAS No. 67814-76-0. Pack Sizes: 100 mg. Product ID: B0084-096802. Molecular formula: C22H45N5O16S. Mole weight: 667.68. Custom synthesis is available. Send your inquiries for more information.
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Kanamycin Sulfate
Kanamycin sulfate is an aminoglycoside antibiotic that has inhibitory effects on gram-positive and negative bacteria and mycoplasma. The mechanism of action is to target the 70S ribosomal subunit of the bacteria to inhibit ribosomes. Translocations and causing erroneous codes further interfere with protein synthesis. It can be used for respiratory and urinary tract infections and sepsis caused by sensitive bacteria, and has a certain effect on swine asthma and atrophic rhinitis. Group: Pharmaceutical. Alternative Names: Kanamycin, sulfate (salt). CAS No. 70560-51-9. Pack Sizes: 1mg;1g;10g. Product ID: 70560-51-9. Custom synthesis is available. Send your inquiries for more information.
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Ku-0063794
KU-0063794 is an inhibitor of both mTORC1 and mTORC2 with an IC50 of approximately 10 nM, but does not suppress the activity of 76 other protein kinases or seven lipid kinases, including Class 1 PI3Ks (phosphoinositide 3-kinases) at 1000-fold higher concentrations. KU-0063794 is cell permeant, suppresses activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK (ribosomal S6 kinase), an AGC kinase not regulated by mTOR. It also inhibited phosphorylation of the T-loop Thr308 residue of Akt phosphorylated by PDK1 (3-phosphoinositide-dependent protein kinase-1). It does not affect Thr308 phosphorylation in fibroblasts lacking essential mTORC2 subunits. KU-0063794 also suppressed cell growth and induced a G1-cell-cycle arrest. KU-0063794 will be useful in delineating the physiological roles of mTOR and may have utility in treatment of cancers in which this pathway is inappropriately activated. Uses: Differentiation. Group: Pharmaceutical. Alternative Names: KU0063794; KU-0063794; KU 0063794; Ku0063794; Ku 0063794; Ku-0063794; KU63794; KU 63794; KU-63794; [5-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-morpholin-4-ylpyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol. CAS No. 938440-64-3. Pack Sizes: 100 mg. Product ID: B0084-100850. Molecular formula: C25H31N5O4. Mole weight: 465.554. Custom synthesis is available. Send your inquiries for more information.
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Linezolid
Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Linezolid is a synthetic oxazolidinone antibiotic active against a wide range of Gram-positive bacteria, including resistant strains of several species, such as MRSA and penicillin-resistant pneumococci. Group: Pharmaceutical. Alternative Names: Zyvox; Zyvoxid; Zyvoxam; PNU 100766; PNU-100766; PNU100766; U 100766; U-100766; U100766. CAS No. 165800-03-3. Pack Sizes: 50 mg. Product ID: BBF-04161. Molecular formula: C16H20FN3O4. Mole weight: 337.35. Custom synthesis is available. Send your inquiries for more information.
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Linezolid Impurity 42
An impurity of Linezolid. Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Group: Pharmaceutical. Alternative Names: 2-amino-3-chloropropan-1-ol; Linezolid Impurity 42; 725676-93-7; AKOS006352833. CAS No. 725676-93-7. Pack Sizes: 10 mg. Product ID: B2694-338786. Molecular formula: C3H8ClNO. Mole weight: 109.55. Custom synthesis is available. Send your inquiries for more information.
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Linezolid Impurity 44
An impurity of Linezolid. Linezolid inhibits initiation complex formation with either the 30S or the 70S ribosomal subunits from Escherichia coli. Group: Pharmaceutical. Alternative Names: N-[(2S)oxiranylmethyl]acetamide; Acetamide, N-[(2S)-oxiranylmethyl]-; N-[[(2S)-oxiran-2-yl]methyl]acetamide; (S)-(+)-N-(oxiranylMethyl)acetaMide; (S)-N-oxiranylmethyl-acetamide; SCHEMBL2863034; (s)-n-(oxiranylmethyl)acetamide; DTXSID80453297; HBTVZPMDLRPWKZ-YFKPBYRVSA-N; N-[(2S)oxiranylmethyl] acetamide; (S)-N-(Oxiran-2-ylmethyl)acetamide; CS-0166034; (S)-N-(oxiran-2-ylmethyl)acetamide? (Brexpiprazole Impurity pound(c). CAS No. 183805-10-9. Pack Sizes: 2 mg. Product ID: B2694-338787. Molecular formula: C5H9NO2. Mole weight: 115.13. Custom synthesis is available. Send your inquiries for more information.
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Minocycline hydrochloride
Minocycline (INN) is a semi-synthetic broad-spectrum tetracycline antibiotic. Minocycline hydrochloride is the most lipid-soluble form, which binds to the 30S ribosomal subunit, preventing the binding of tRNA to the mRNA-ribosome complex and interfering with protein synthesis. In combination with CHIR 99021, (S)-(+)-Dimethindene maleate and human leukemia inhibitory factor, it induces the formation of extended pluripotent stem (EPS) cells. Group: Pharmaceutical. Alternative Names: Minocycline HCl; Arestin; Minomycin. CAS No. 13614-98-7. Pack Sizes: 5 g. Product ID: BBF-03822. Molecular formula: C23H27N3O7.HCl. Mole weight: 493.94. Custom synthesis is available. Send your inquiries for more information.
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m-Methoxytopolin riboside
It can be used in biological study in influence of plant growth regulators on shoot proliferation and secondary metabolite production in micropropagated Huernia hystrix. Group: Pharmaceutical. Alternative Names: N6-(m-Methoxybenzyl)adenosine; Mem-TR; 6-(3-Methoxybenzylamino)-9-b-D-ribofuranosylpurine; N6-(3-Methoxybenzyl)adenosine; N-(3-Methoxybenzyl)adenosine; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methoxybenzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol; meta-Methoxytopolin Riboside; N-[(3-Methoxyphenyl)methyl]adenosine. CAS No. 101565-95-1. Pack Sizes: 1 g. Product ID: B2706-291769. Molecular formula: C18H21N5O5. Mole weight: 387.39. Custom synthesis is available. Send your inquiries for more information.
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N1, N4-Bis-Boc-Spermidine
An impurity of Spermidine. Spermidine is a polyamine compound found in ribosomes and living tissues, and having various metabolic functions within organisms. Group: Pharmaceutical. Alternative Names: Carbamic acid; N-(4-aminobutyl)?-N-[3-[[(1,?1-dimethylethoxy)?carbonyl]?amino]?propyl]?-, 1,?1-dimethylethyl ester; N1,N4-Di-(tert-butoxycarbonyl)spermidine. CAS No. 85503-20-4. Pack Sizes: 100 mg. Product ID: BAT-009037. Molecular formula: C17H35N3O4. Mole weight: 345.48. Custom synthesis is available. Send your inquiries for more information. Categories: N1,N4-Bis-Boc-Spermidine.
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N6-Benzyl Adenosine
A selective A1 adenosine receptor agonist. Group: Pharmaceutical. Alternative Names: N6-Benzyladenosine; 6-Benzylaminopurine Riboside; N-(Phenylmethyl)adenosine; 6-(Benzylamino)-9-β-D-ribofuranosylpurine; 6-Benzyladenosine; NSC 70423. CAS No. 4294-16-0. Pack Sizes: 10 g. Product ID: B2706-317295. Molecular formula: C17H19N5O4. Mole weight: 357.36. Custom synthesis is available. Send your inquiries for more information.
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N6-(cis-hydroxyisopentenyl)adenosine
N6-(cis-hydroxyisopentenyl)adenosine is a remarkable biochemical compound, used for studying an array of ailments and circumstances including breast and lung cancer. Swiftly, it embraces anti-inflammatory traits thus used for studying diseases of inflammation, particularly the notorious rheumatoid arthritis. Group: Pharmaceutical. Alternative Names: Adenosine, N-(4-hydroxy-3-methyl-2-butenyl)-, (Z); 9-beta-D-ribofuranosyl-cis-zeatin; (2R,3R,4S,5R)-2-(6-(((Z)-4-Hydroxy-3-methylbut-2-en-1-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; cis-Zeatin riboside; 9-ribosyl-cis-zeatin; 9-ribosylzeatin. CAS No. 15896-46-5. Pack Sizes: 5 mg. Product ID: B1370-001245. Molecular formula: C15H21N5O5. Mole weight: 351.36. Custom synthesis is available. Send your inquiries for more information.
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N6-isopentenyladenosine
It is a cytokinin growth regulator that can be produced endogenously by plants to guide the differentiation of callus cells. In the research of anticancer drugs, it can induce cell cycle contraction and apoptosis. Uses: Plant growth regulators. Group: Pharmaceutical. Alternative Names: N6-(2-Isopentenyl)adenosine; Isopentenyladenosine riboside; N-(3-Methyl-2-butenyl)-adenosine; 6-(3-Methyl-2-butenylamino)-9-β-D-ribofuranosylpurine; 6-(3-Methyl-2-butenylamino)purine riboside; 6-(γ,γ-Dimethylallylamino)purine riboside; N-Isopentenyladenosine; N6-(3-Methyl-2-butenyl)adenosine; NSC 105546; Riboprine; Isopentenyladenosine. CAS No. 7724-76-7. Pack Sizes: 5 g. Product ID: BBF-04042. Molecular formula: C15H21N5O4. Mole weight: 335.36. Custom synthesis is available. Send your inquiries for more information.
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Nebularine
Nebularine is originally isolated from Agaricus nebularis. Shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria. Group: Pharmaceutical. Alternative Names: 9-(beta-D-Ribofuranosyl)-9H-purine; Purine riboside; Purine-9-β-D-ribofuranoside; 9-β-D-Ribofuranosyl-9H-purine; Ribosyl-isopurine; N-D-Ribosylpurine; Purinosine; NSC 65423; 6-Deaminoadenosine; 9-β-D-Ribofuranosylpurine; 9-β-D-Ribosyl-9H-purine; Desaminoadenosine; Isopurine, ribosyl-; Ribosylpurine. CAS No. 550-33-4. Pack Sizes: 1 g. Product ID: BBF-02595. Molecular formula: C10H12N4O4. Mole weight: 252.23. Custom synthesis is available. Send your inquiries for more information.
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Nicotinamide riboside chloride
Nicotinamide riboside chloride. Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 23111-00-4. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications.
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