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Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Group: Pharmaceutical. CAS No. 183552-38-7. Pack Sizes: 10 mg. Product ID: BAT-006166. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Amrinone
Amrinone is a selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. It is a simple, non-glycoside cardiotonic agent. It provides protection against ischemia-reperfusion injury in kidney, liver, and heart. It has the ability to stimulate calcium ion influx into the cardiac cell. It is used in the treatment of congestive heart failure. It increases cardiac contractility as a vasodilator. It acts by inhibiting the breakdown of both cAMP and cGMP by the phosphodiesterase (PDE3) enzyme. It is a drug that may improve the prognosis in patients with congestive heart failure. It has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). It was developed by Sanofi and has been listed. Uses: Amrinone is a simple, non-glycoside cardiotonic agent. it provides protection against ischemia-reperfusion injury in kidney, liver, and heart. it is used in the treatment of congestive heart failure. it increases cardiac contractility as a vasodilator. Group: Pharmaceutical. CAS No. 60719-84-8. Pack Sizes: 2.5 g. Product ID: B0084-072903. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Arbidol hydrochloride
Arbidol is an antiviral agent used for the treatment of influenza infection in Russia and China. It has been used against influenza A and B viruses, and hepatitis C virus (HCV). It has been shown that ARB could inhibit COVID-19 infection through interfering the release of SARS-CoV-2 from intracellular vesicles. It can be used to treat trypanosomiasis in livestock. Group: Pharmaceutical. CAS No. 131707-23-8. Pack Sizes: 1 g. Product ID: NP3436. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Bombesin
Bombesin is a neuropeptide with many biological effects such as hormone release, activation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion. It binds to the gastrin-releasing peptide receptor (GRPR) in rat pancreatic acinar cells (Ki = 1.88 nM), and also to frog bombesin receptor subtype 4 (BB4) in CHO cells overexpressing the receptor (Ki = 1.7 nM). Uses: Neurotransmitter agents. Group: Pharmaceutical. CAS No. 31362-50-2. Pack Sizes: 10 mg. Product ID: BAT-006169. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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C10 Aromatic Naphtha
A clear colourless liquid with a mild aromatic odour. Its a flammable liquid with a boiling point between 181-205° C. C10 aromatic solvent is a member of the petroleum hydrocarbon family and is predominantly made up of c9-c11 aromatic hydrocarbons. Uses: Manufacture of substances, Distribution of substance, Formulation & (re) packing of substances and mixture, Uses in coatings, Use in cleaning agent, Use in oil and gas field drilling and production operations, Lubricants, Metal working fluids / rolling oils, Use as binders and releaseagents, Use as a fuel, Functional Fluids, Road and construction applications, Use in laboratories, Polymer processing, Water treatment chemicals. Alternative Names: Aromatic 150. CAS No. 64742-94-5.
Ceritinib
An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 1032900-25-6. Pack Sizes: 250 mg. Product ID: B0084-462148. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Diazoxide
Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular release of potassium switches off voltage-gated calcium ion channels which inhibits the generation of an action potential. Uses: Antihypertensive agents. Group: Pharmaceutical. CAS No. 364-98-7. Pack Sizes: 2 g. Product ID: B0084-474147. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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D-Val-Leu-Lys 4-nitroanilide dihydrochloride
D-Val-Leu-Lys 4-nitroanilide dihydrochloride stands as a crucial substrate to gauge the efficiency of trypsin-like serine proteases. Proteolysis event leads to the release of a yellow colored product, whose quantification can be done at 405 nm. Its utility can be seen in trypsin activity detection and the evaluation of agents restricting trypsin-like proteases. Consistent usage of this product aids in experimental design and the analysis of diverse protease substrates. Group: Pharmaceutical. CAS No. 62354-43-2. Pack Sizes: 5 mg. Product ID: BAT-014255. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Erastin
Erastin is an antitumor agent selective for tumor cells bearing oncogenic RAS (i.e. HRAS, KRAS). Erastin produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel (VDAC) gating allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death. Erastin blocks and reverses mitochondrial depolarization after microtubule destabilizers in intact cells and antagonized tubulin-induced VDAC blockage in planar bilayers. Reversal of tubulin-VDAC interaction by erastin antagonizes Warburg metabolism and restores oxidative mitochondrial metabolism. Group: Pharmaceutical. CAS No. 571203-78-6. Pack Sizes: 100 mg. Product ID: B0084-300990. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Fenofibric acid
Fenofibric acid is a lipid regulating agent available as delayed release capsules for oral administration. Group: Pharmaceutical. CAS No. 42017-89-0. Pack Sizes: 100 g. Product ID: NP3513. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Homoeriodictyol
Homoeriodictyol is a natural compound isolated from the herbs of Taxillus sutchuenensis. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotonin release in differentiated Caco-2 cells. Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. Group: Pharmaceutical. CAS No. 446-71-9. Pack Sizes: 10 mg. Product ID: NP1981. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Lanreotide
Laromustine is a sulfonyl hydrazine prodrug with antineoplastic activity. Laromustine releases the DNA chloroethylating agent 90CE after entering the blood stream; 90CE chloroethylates alkylates the 06 position of guanine, resulting in DNA crosslinking, strand breaks, chromosomal aberrations, and disruption of DNA synthesis. Intracellular metabolism of this agent also releases methyl isocyanate which inhibits 06-alkyl-guanine transferase, an enzyme involved with DNA repair. Group: Pharmaceutical. CAS No. 108736-35-2. Pack Sizes: 25 mg. Product ID: BAT-010202. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Lithium stearate
A white soft solid, prepared by the reaction of lithium hydroxide and stearic acid. Lithium stearate and lithium 12-hydroxystearate are lithium soaps and are components of lithium greases and releaseagents. Uses: Laboratory chemicals, Industrial & for professional use. CAS No.:4485-12-5.
Magnesium aluminosilicate
Magnesium aluminosilicate has long been used in the formulation of tablets, ointments and creams. It is used as a suspension and stabilizer alone or in combination with other suspension agents in oral and topical formulations. In tablets, it is used as a binder and disintegrating agent in conventional or sustained-release preparations. Group: Pharmaceutical. CAS No. 1327-43-1. Pack Sizes: 100 g. Product ID: B1370-014007. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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Olopatadine hydrochloride
Olopatadine HCl is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 140462-76-6. Pack Sizes: 5 g. Product ID: NP3222. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
SETTING WAX FOR FEATURES. Uses: Setting wax for difficult release features. Group: Construction. Pack Sizes: 20 ltr. Categories: ReleaseAgents.
GLASGOW
OPUS OPTIMUM CR2
BIO RELEASEAGENT. Uses: Safe bio release site and large panel precast. Group: Construction. Pack Sizes: 1000 ltr IBC, 205 Ltr, 20 Ltr. Categories: ReleaseAgents.
GLASGOW
OPUS OPTIMUM SE
BIO RELEASEAGENT. Uses: Water based bio releaseagent. quick drying. Group: Construction. Pack Sizes: 1000 ltr IBC, 205 Ltr, 20 Ltr. Categories: ReleaseAgents.
GLASGOW
Plitidepsin
Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin shows potent anticancer activity against a large variety of cultured human cancer cells, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth. Group: Pharmaceutical. CAS No. 137219-37-5. Pack Sizes: 1 mg. Product ID: BAT-010093. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Rhoifolin
Rhoifolin is a natural flavonoid isolated from the leaves of Turpinia arguya Seem. It may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation. Rhoifolin inhibits the activity of anti-inflmmatory and increases the total antioxidant capacity in a reverse dose order, which can cause a time and reverse dose dependent reduction of carrageenin-induced rat paw oedema, significantly abrogate prostaglandin E2 level, significantly diminish the TNF-a release in the inflammatory exudates. The compound could also be used as an ideal anticancer agent, and it discriminates between cancerous and non cancerous cell as it kills only the former one, so the side effects which may appear during chemotherapy could be overcome. Uses: Anti-inflammatory; anti-cancer. Group: Pharmaceutical. CAS No. 17306-46-6. Pack Sizes: 25 mg. Product ID: NP1948. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Saikosaponin D
Saikosaponin D is extracted from the root of Bupleurum chinense DC. It protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling. It possesses potent cytotoxicity against human hepatocellular carcinoma cells. It inhibits cell growth of human cancer cells by inducing apoptosis and blocking cell cycle progression in the G1 phase. It was found to stimulate corticotropin-releasing factor (CRF) gene expression and CRF release. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 20874-52-6. Pack Sizes: 20 mg. Product ID: NP7004. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
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SINOACUTINE
Sinoacutine, a natural alkaloid sourced from flora, boasts analgesic and anti-inflammatory properties backed by clinical research. The compound's potential in treating inflammatory diseases, including rheumatoid arthritis, has been subject to investigations. Sinoacutine's efficacy in regulating immune responses is attributable to its ability to obstruct the release of inflammatory cytokines, rendering it a viable candidate in the development of novel anti-inflammatory agents. Group: Pharmaceutical. CAS No. 4090-18-0. Pack Sizes: 5 mg. Product ID: NP0371. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Tiaramide hydrochloride
Tiaramide is an anti-inflammatory drug that inhibits the action of mediators released from mast cells and has direct smooth muscle relaxant properties. It is commonly used in the treatment of asthma. Uses: Anti-inflammatory agents, non-steroidal. Group: Pharmaceutical. CAS No. 35941-71-0. Pack Sizes: 25 mg. Product ID: B2692-018999. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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