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Ac-Tyr-Arg-cetyl ester is an ingredient in anti-wrinkle cosmetics. It can inhibit the production of calcitonin gene-relatedpeptide (CGRP), produce β-endorphins, and raise the threshold of skin sensitivity to heat. Group: Pharmaceutical. CAS No. 196604-48-5. Pack Sizes: 5 mg. Product ID: BAT-006228. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Agouti-related Protein (AGRP) (25-82), human
Agouti-related protein (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It acts as a melanocortin receptor antagonist that exerts a central inhibitory action on the Hypothalamic-Pituitary-Thyroid (HPT) Axis. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BAT-006143. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
α-CGRP (human) TFA
α-CGRP (human) is an endogenous calcitonin gene-relatedpeptide receptor (CGRP) agonist. Group: Pharmaceutical. Pack Sizes: 50 mg. Product ID: BAT-016129. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Bacitracin
Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synth. Uses: Topical preparation. Group: Pharmaceutical. CAS No. 1405-87-4. Pack Sizes: 10 g. Product ID: BBF-05843. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Bacitracin A-[d7]
Labelled Bacitracin. Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, which disrupts both gram positive and gram negative bacteria by interfering with cell wall and peptidoglycan synth. Group: Pharmaceutical. Pack Sizes: 0.5 mg. Product ID: BLP-003382. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
CRAMP (mouse)
This cathelicidin-related antimicrobial peptide (CRAMP) is the sole murine cathelicidin. CRAMP expression in the intestinal tract is restricted to surface epithelial cells in the colon. CRAMP shows antimicrobial activity against the murine enteric pathogen Citrobacter rodentium and destroys skin Candida albicans. Group: Pharmaceutical. CAS No. 376364-36-2. Pack Sizes: 5 mg. Product ID: B1370-196726. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
FOXO4-DRI
FOXO4-DRI is a peptide acting as a specific FOXO4 blocker. It has been demonstrated to alleviate age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Group: Pharmaceutical. Pack Sizes: 1 mg. Product ID: BAT-006150. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
GPRP acetate
GPRP acetate, a fibrinogen-relatedpeptide, inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). Group: Pharmaceutical. CAS No. 157009-81-9. Pack Sizes: 100 mg. Product ID: BAT-009226. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Loureirin A
Loureirin A is a chalcone extracted from the red resin of the herbs of Dracaena cochinchinensis, which is known as Dragon's Blood. It is a part of traditional Chinese medicine which helps combat neurodegenerative diseases. It inhibits platelet activation by an impairment of PI3K/Akt signaling. It also could inhibit Akt phosphorylation. It negatively affects agonist-induced platelet aggregation such as ADP, collagen, thrombin and collagen-relatedpeptide (CRP). It promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound by activating Wnt/-catenin pathway. Group: Pharmaceutical. CAS No. 119425-89-7. Pack Sizes: 250 mg. Product ID: NP0980. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Olcegepant
Olcegepant, also called as BIBN4096BS or BIBN 4096, is the first potent and selective non-peptide antagonist of the calcitonin gene-relatedpeptide 1 (CGRP1) receptor(IC50= 0.03 nM) and has been shown to block all effects of infused CGRP (2) and should ef. Group: Pharmaceutical. CAS No. 204697-65-4. Pack Sizes: 10 mg. Product ID: B0084-441440. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
Oxytocin Impurities
Oxytocin Impurities, intricately utilized within biomedical realms, serve as crucial agents for evaluating the purity and efficacy of oxytocin formulations. These impurities are vital in ensuring the safety and therapeutic potency of oxytocin, a peptide hormone primarily employed to manage childbirth-related conditions like labor induction and postpartum hemorrhage. Group: Pharmaceutical. Pack Sizes: 1mg; 1g; 10g. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
RC 160
RC 160 is a cyclic octapeptide somatostatin analog (Ki= 0.7, 5.4, 30.9, 45 and > 1000 nM for sst5, sst2, sst3, sst4 and sst1 receptors respectively). RC 160 is a peptide neurokinin-1 receptor (NK1) antagonist and inhibits increases in vascular permeability stimulated by substance P in a concentration-dependent manner in isolated guinea pig trachea and main bronchi. It is used in the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and AIDS-related diarrhea. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 103222-11-3. Pack Sizes: 5 mg. Product ID: BAT-006135. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
SR1001
Retinoic-acid-receptor-related orphan receptors (ROR) α and γ play a key role in the development of T-helper cells that produce interleukin-17 (TH17 cells), a subset of CD4+ T-cells that contribute to the inflammatory process and have been implicated in the pathology of autoimmune diseases. SR 1001 is a synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist at these receptors. SR 1001 has been shown to suppress IL-17 promoter driven transcriptional activity by inhibiting the interaction of co-activators such as TRAP220 nuclear receptor box 2 peptide (IC50 = 117 nM) and SRC2 with RORα and RORγ as well as by increasing the recruitment of corepressors such as NCoR. At 5 μM, SR 1001 inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs. A 25 mg/kg dose of SR 1001 twice/day delays the onset and the severity of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis. Group: Pharmaceutical. CAS No. 1335106-03-0. Pack Sizes: 100 mg. Product ID: B1370-463179. Molecular formula: Custom synthesis is available. Send your inquiries for more information.
London
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