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| Product | Description | |
|---|---|---|
| Quinazoline 98% | 5g Pack Size. Group: Building Blocks, Organics. Formula: C8H6N2. CAS No. 253-82-7. Prepack ID : 13438099-5g. Molecular Weight : 130.15. |  |
| 3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl acetate (CAS 371947-93-2) | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl acetate (CAS 371947-93-2). Uses: Pharmaceuticals, Personal Care, Industrial. Grades: Pharma, Cosmetic, Food, Feed, Technical. CAS No. 371947-93-2. Pack Sizes: Bulk. Cenik is your partner of choice for Hard-to-find chemicals. We don't just provide products, we supply solutions to your technical and regulatory specifications. |  Cenik Chemicals |
| 4-Chloro-5,6,7,8-tetrahydroquinazolin-6-one | 4-Chloro-5,6,7,8-tetrahydroquinazolin-6-one is a multifaceted organic entity utilized as a pivotal precursor in the construction of several paramount medicaments. Several studies have identified its potent efficacy for combating cancer cells, thus, exhibiting high cytocidal behavior. The design and formulation of this chemical intermediate present promising breakthroughs for developing potential therapeutic agents for an array of neoplastic diseases, most notably breast and colorectal cancer. Group: Pharmaceutical. CAS No. 944895-88-9. Pack Sizes: 5 g. Product ID: B2699-278624. Molecular formula: Custom synthesis is available. Send your inquiries for more information. |  London |
| 4-N-(3-Chloro-4-fluorophenyl)-7-[(3R)-oxolan-3-yl]oxyquinazoline-4,6-diamine | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Group: Pharmaceutical. CAS No. 402855-03-2. Pack Sizes: 10 mg. Product ID: B2694-292473. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6,7-dimethoxy-2-piperazin-1-ylquinazolin-4-amine hydrochloride | One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic blocker. Group: Pharmaceutical. CAS No. 70843-11-7. Pack Sizes: 20 mg. Product ID: B2694-338833. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| 6-(Benzyloxy)-4-(3-chloro-4-fluorophenylamino)-7-methoxy-quinazoline | 6-(Benzyloxy)-4-(3-chloro-4-fluorophenylamino)-7-methoxy-quinazoline (CAS# 913819-12-2 ) is a useful research chemical. Group: Pharmaceutical. CAS No. 913819-12-2. Pack Sizes: 1 g. Product ID: B2699-100471. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-[4-[ (3-Chloro-4-fluorophenyl)amino]-7-[[ (3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4- (dimethylamino)-2-butenamide | N-[4-[ (3-Chloro-4-fluorophenyl)amino]-7-[[ (3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4- (dimethylamino)-2-butenamide is an impurity of Afatinib, which is a tyrosine kinase inhibitor used to treat non-small cell lung carcinoma (NSCLC). Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 439081-18-2. Pack Sizes: 500 mg. Product ID: B0084-092426. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| tert-butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate | One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic blocker. Group: Pharmaceutical. CAS No. 1260939-66-9. Pack Sizes: 20 mg. Product ID: B2694-338832. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Febrifugine dihydrochloride | Febrifugine is a quinazolinone alkaloid isolated from the Chinese herb Dichroa febrifuga. Group: Pharmaceutical. CAS No. 32434-42-7. Pack Sizes: 25 mg. Product ID: B2703-334742. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Halofuginone | Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibro-proliferative diseases. Uses: Semisynthetic quinazolinone alkaloid anticoccidial. Group: Pharmaceutical. CAS No. 55837-20-2. Pack Sizes: 100 mg. Product ID: B0084-071625. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Icotinib hydrochloride | Icotinib Hydrochloride is a quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), which is upregulated in a variety of cancer cell types. Icotinib supresses the cancer cell proliferation via EGFR tyrosine kinase inhibition. Group: Pharmaceutical. CAS No. 1204313-51-8. Pack Sizes: 300 mg. Product ID: BBF-04036. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Ispinesib | Ispinesib is a synthetic small molecule, derived from quinazolinone, with antineoplastic properties. Ispinesib selectively inhibits the mitotic motor protein, kinesin spindle protein (KSP), resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and cell death in tumor cells that are actively dividing. Because KSP is not involved in nonmitotic processes, such as neuronal transport, ispinesib may be less likely to cause the peripheral neuropathy often associated with the tubulin-targeting agents. Group: Pharmaceutical. CAS No. 336113-53-2. Pack Sizes: 50 mg. Product ID: B0084-066412. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| Lapatinib Ditosylate | Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Uses: Antineoplastic agents. Group: Pharmaceutical. CAS No. 388082-77-7. Pack Sizes: 1 g. Product ID: B0084-067756. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
| N-Boc-1,2,3,6-tetrahydropyridine-4-boronic Acid Pinacol Ester | Reagent used for : Suzuki-Miyaura cross-coupling using palladium phosphine catalyst ; Palladium-catalyzed ligand-controlled regioselective Suzuki coupling ; Palladium-catalyzed Suzuki-Miyaura coupling ; Suzuki coupling followed by iodolactonization reaction ; Wrenchnolol derivative optimized for gene activation in cells Reagent used in Preparation of several enzymatic inhibitors and receptor ligands; Orally active anaplastic lymphoma kinase inhibitors ; Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes ; 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cyclopropanecarboxamides as novel melatonin receptor ligands ; Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder ; Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists. Group: Pharmaceutical. CAS No. 286961-14-6. Pack Sizes: 100 g. Product ID: BB019917. Molecular formula: Custom synthesis is available. Send your inquiries for more information. | London |
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