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Pyrrolidinyl diaminopyrimidine oxide is structurally similar to minoxidil and is an innovative and clinically proven 100% water soluble alcohol-free hair growth promoter. Pyrrolidinyl diaminopyrimidine oxide improves the skin surface blood circulation, to the hair roots to provide the required nutrients and oxygen, to achieve the effect of inhibiting hair loss, strengthening the hair roots, and promoting hair growth. By opening potassium ion channels, it can transform hair follicles from resting period to growth period and prolong the growth period of hair. Group: Pharmaceutical. Alternative Names: 2,4-Pyrimidinediamine, 6-(1-pyrrolidinyl)-, 3-oxide; 2,4-Diamino-6-pyrrolidinopyrimidine 3-oxide; 2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide; Nanoxidil; Triaminodil; Copyrrol. CAS No. 55921-65-8. Pack Sizes: 50 g. Product ID: B1370-125349. Molecular formula: C8H13N5O. Mole weight: 195.22. Custom synthesis is available. Send your inquiries for more information.
1-(Chloro-1-Pyrrolidinylmethylene) Pyrrolidinium tetrafluoroborate Uses: Pharmaceutical Research and Development. Group: Coupling Reagents. CAS No. 115007-14-2. Pack Sizes: Enquire for MOQ. Categories: NORDMANN innovative sourcing and supply.
2-butoxy-7-[[4-(1-pyrrolidinylmethyl)phenyl]methyl]-5H-pyrrolo[3,2-d]pyrimidin-4-amine, a medicinal molecule known for its kinase-inhibiting properties, has been identified as a potential candidate for cancer therapy due to its unique ability to induce apoptosis and inhibit the proliferation of malignant cells. With promising applications in the treatment of leukemia and lung cancer, this small-molecule inhibitor has the potential to address critical unmet clinical needs in cancer management. Its effectiveness and suitability as a therapeutic intervention call for further investigation in the field of oncology. Group: Pharmaceutical. Alternative Names: 5H-Pyrrolo[3,2-d]pyrimidin-4-amine, 2-butoxy-7-[[4-(1-pyrrolidinylmethyl)phenyl]methyl]-. CAS No. 1878111-20-6. Pack Sizes: 5 mg. Product ID: B0001-008679. Molecular formula: C22H29N5O. Mole weight: 379.51. Custom synthesis is available. Send your inquiries for more information.
(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1- pyrrolidinylphosphonium hexafluorophosphate Uses: Pharmaceutical Research and Development. Group: Coupling Reagents. Alternative Names: PyAOP. CAS No. 156311-83-0. Pack Sizes: Enquire for MOQ. Categories: NORDMANN UK Fine Chemicals: innovative sourcing and supply.
(S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINYL METHYLTMS ETHER Uses: Pharmaceutical Research and Development. Group: Intermediates. CAS No. 848821-58-9. Pack Sizes: Enquire for MOQ. Categories: Nordmann UK Fine Chemicals suppliers (Formerly Melrob-Eurolabs).
UK / EU / USA / Japan
(2R,4R)-Teneligliptin
One isomer form of Teneligliptin, which is a DPP-4 inhibitor and has been found to be effective in the treatment of type 2 diabetes. Group: Pharmaceutical. Alternative Names: Teneligliptin (2R,4R)-Isomer; [(2R,4R)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinylmethanone. CAS No. 1404559-17-6. Pack Sizes: 10 mg. Product ID: B2694-483037. Molecular formula: C22H30N6OS. Mole weight: 426.59. Custom synthesis is available. Send your inquiries for more information.
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3-Carboxy-proxyl
3-Carboxy-proxyl - a remarkably stable nitroxide radical that serves as a spin-label in electronic paramagnetic resonance (EPR) spectroscopy. Boasting wide-ranging applications in biosciences, 3-Carboxy-proxyl has been extensively utilized for scrutiny of an assortment of biological systems, comprising enzymes, membrane proteins, and DNA. Moreover, its potential therapeutic applications, including the treatment of neurological disorders like stroke and neurodegenerative diseases, have been the focus of extensive analysis. Group: Pharmaceutical. Alternative Names: 3-(Carboxy)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, 3-Carboxy-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical. CAS No. 2154-68-9. Pack Sizes: 5 g. Product ID: B2699-187805. Molecular formula: C9H17NO3. Mole weight: 187.24. Custom synthesis is available. Send your inquiries for more information.
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7-Epi Clindamycin
7-Epi Clindamycin, a highly efficacious antibiotic, exhibits remarkable efficacy against a wide range of bacterial infections. By discerningly impeding protein synthesis within bacterial organisms, it disrupts their growth and obstructs their survival, effectively eliminating the pernicious microorganisms. Distinctively versatile, this compound demonstrates its unwavering effectiveness against both Gram-positive and Gram-negative bacteria. Consequently, this invaluable asset plays an integral role in the biomedical field, diligently combatting infectious ailments with exceptional efficacy. Group: Pharmaceutical. Alternative Names: D-erythro-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, trans-α-; D-erythro-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, (2S-trans)-; Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; 7-Epiclindamycin; Antibiotic U 21251F. CAS No. 16684-06-3. Pack Sizes: 5 mg. Product ID: B1370-159244. Molecular formula: C18H33ClN2O5S. Mole weight: 424.98. Custom synthesis is available. Send your inquiries for more information.
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7-Epiclindamycin 2-Phosphate
7-Epiclindamycin 2-Phosphate is an impurity of Clindamycin, an antibiotic medication used for the treatment of bacterial infections. Group: Pharmaceutical. Alternative Names: 7-Epiclindamycin phosphate; Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside 2-(Dihydrogen Phosphate); Clindamycin Phosphate EP Impurity L. CAS No. 620181-05-7. Pack Sizes: 1 mg. Product ID: B1370-119595. Molecular formula: C18H34ClN2O8PS. Mole weight: 504.96. Custom synthesis is available. Send your inquiries for more information.
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7-Epi Lincomycin Hydrochloride Salt
7-Epi Lincomycin Hydrochloride Salt is an epimer of Lincomycin, a 6-amino, 6-deoxy-octopyraninose with strong antibiotic activity. It is less potent bactericidal than its (7R)-epimer. Group: Pharmaceutical. Alternative Names: Methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1- thio-L-threo-α-D-galacto-octopyranoside Hydrochloride; trans-α-Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)- 1-thio-L-threo-D-galacto-octopyranoside. CAS No. 26389-84-4. Pack Sizes: 5 mg. Product ID: B2694-472409. Molecular formula: C18H35ClN2O6S. Mole weight: 443. Custom synthesis is available. Send your inquiries for more information.
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A 331440 dihydrochloride
A 331440 dihydrochloride is a histamine H3 receptor antagonist (Ki = 21.7 and 22.7 nM for rat and human H3 receptors, respectively). A 331440 reduces weight in a diet-induced obesity model. Group: Pharmaceutical. Alternative Names: A-331440 dihydrochloride; A 331440 dihydrochloride; A331440 dihydrochloride; 4'-[3-[(3R)-3-(Dimethylamino)-1-pyrrolidinyl]propoxy]-[1,1'-biphenyl]-4-carbonitrile dihydrochloride. CAS No. 1049740-32-0. Pack Sizes: 1mg;1g;10g. Product ID: 1049740-32-0. Molecular formula: C22H27N3O.2HCl. Mole weight: 422.39. Custom synthesis is available. Send your inquiries for more information.
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A37
A37 is an aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC50 = 4.6 μM; Ki = 300 nM). It competitively binds to the aldehyde binding pocket of ALDH1A1, resulting in the disruption of spheroid formation and a decrease of cell viability in ovarian cancer cells in vitro. Group: Pharmaceutical. Alternative Names: Ethyl 2-[[3,4-dihydro-4-oxo-3-[3-(1-pyrrolidinyl)propyl][1]benzothieno[3,2-d]pyrimidin-2-yl]thio]acetate; CM037; CM-037; CM 037; A37; A-37; A 37. CAS No. 896795-60-1. Pack Sizes: 1mg;1g;10g. Product ID: 896795-60-1. Molecular formula: C21H25N3O3S2. Mole weight: 431.57. Custom synthesis is available. Send your inquiries for more information.
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ABT 089 dihydrochloride
ABT 089 dihydrochloride is a selective α4β2 nicotinic acetylcholine receptor partial agonist (Ki = 16 nM) with >1000-fold and >10,000-fold selectivity for α4β2 over α1β1γ1 and α7 receptors, respectively. ABT 089 dihydrochloride is used as a nootropic and neuroprotective agent. Uses: Nootropic and neuroprotective agent. Group: Pharmaceutical. Alternative Names: ABT 089 dihydrochloride; ABT089 dihydrochloride; ABT-089 dihydrochloride; 2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride; Pozanicline hydrochloride. CAS No. 161416-61-1. Pack Sizes: 1mg;1g;10g. Product ID: 161416-61-1. Molecular formula: C11H16N2O.2HCl. Mole weight: 265.18. Custom synthesis is available. Send your inquiries for more information.
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ABT279
ABT279 is a bio-active chemical coumpound. It is used for the treatment of type 2 diabetes. It was developed by Abbvie and was in clinical phase 1 trial, but now it is terminated. Uses: Abt279 is used for the treatment of type 2 diabetes. Group: Pharmaceutical. Alternative Names: ABT-279; ABT 279; 4-Pyridinecarboxylic acid, 2-(4-((2-((2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl)-2-oxoethyl)amino)-4-methyl-1-piperidinyl)-. CAS No. 676559-83-4. Pack Sizes: 1mg;1g;10g. Product ID: 676559-83-4. Molecular formula: C21H25N5O3. Mole weight: 395.46. Custom synthesis is available. Send your inquiries for more information.
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Acalabrutinib-[d4]
Acalabrutinib-[d4] is a labelled version of Acalabrutinib. Acalabrutinib, also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. It inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. Group: Pharmaceutical. Alternative Names: (S)-4-(8-amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl-d4)benzamide; Acalabrutinib D4; Acalabrutinib-d4; 4-[8-Amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide-d4; ACP 196-d4; Calquence-d4. CAS No. 2699608-18-7. Pack Sizes: 5 mg. Product ID: BLP-003188. Molecular formula: C26H19D4N7O2. Mole weight: 469.53. Custom synthesis is available. Send your inquiries for more information.
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Acryloyl-X SE
Acryloyl-X SE. Group: Pharmaceutical. Alternative Names: 2,5-Dioxopyrrolidin-1-yl 6-acrylamidohexanoate; Hexanoic acid, 6-[(1-oxo-2-propen-1-yl)amino]-,2,5-dioxo-1-pyrrolidinyl ester; Acryloyl-X, SE. CAS No. 63392-86-9. Pack Sizes: 250 mg. Product ID: B1370-040075. Molecular formula: C13H18N2O5. Mole weight: 282.29. Custom synthesis is available. Send your inquiries for more information.
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Alizapride hydrochloride
Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Group: Pharmaceutical. Alternative Names: 6-Methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide Hydrochloride; Limican; Nausilen; Plitican; Vergentan; N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-methoxy-1H-benzotriazole-6-carboxamide hydrochloride (1:1). CAS No. 59338-87-3. Pack Sizes: 200 mg. Product ID: B0084-095175. Molecular formula: C16H22ClN5O2. Mole weight: 351.83. Custom synthesis is available. Send your inquiries for more information.
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Auristatin F
Auristatin F, a synthetic analog of dolastatin 10, is a cytotoxic tubulin modifier with potent and selective antitumor activity. It is an MMAF analog and cytotoxin in Antibody-drug conjugates. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: N,N-Dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. CAS No. 163768-50-1. Pack Sizes: 25 mg. Product ID: BBF-05829. Molecular formula: C40H67N5O8. Mole weight: 745.99. Custom synthesis is available. Send your inquiries for more information.
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Azido-PEG2-NHS ester
Azido-PEG2-NHS ester is a non-cleavable 2-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs). Group: Pharmaceutical. Alternative Names: Azido-PEG2-CH2CO2-NHS; N3-PEG2-C2-NHS ester; Propanoic acid, 3-[2-(2-azidoethoxy)ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; N3-PEG2-CH2CH2COONHS Ester; Azido-PEG2-NHS; N3-PEG2-SPA; 1-({3-[2-(2-Azidoethoxy)ethoxy]propanoyl}oxy)-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[3-[2-(2-azidoethoxy)ethoxy]-1-oxopropoxy]-; 2,5-Dioxo-1-pyrrolidinyl 3-[2-(2-azidoethoxy)ethoxy]propanoate; N-Succinimido 9-azido-4,7-dioxanonanoate. CAS No. 1312309-64-0. Pack Sizes: 500 mg. Product ID: BADC-00409. Molecular formula: C11H16N4O6. Mole weight: 300.27. Custom synthesis is available. Send your inquiries for more information.
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BIO 5192
BIO 5192 is a selective and potent inhibitor of integrin α4β1 (Very Late Antigen-4; VLA-4) (Kd < 10 pM) with selectivity for α4β1 over a range of other integrins (IC50 values are 1.8, 138, 1053,> 500 and > 10,000 nM for α4β1, α9β1, α2β1, α4β7 and αIIbβ3, respectively). BIO 5192 causes a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels. Group: Pharmaceutical. Alternative Names: BIO-5192; AMD-15057; BIO 5192; AMD 15057; BIO5192; AMD15057; (2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid. CAS No. 327613-57-0. Pack Sizes: 10 mg. Product ID: B2693-119144. Molecular formula: C38H46Cl2N6O8S. Mole weight: 817.78. Custom synthesis is available. Send your inquiries for more information.
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Clindamycin Hydrochloride
Clindamycin hydrochloride is the hydrochloride salt of Clindamycin, which is a semisynthetic antibiotic prepared from Lincomycin. Group: Pharmaceutical. Alternative Names: (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galactooctopyranoside Hydrochloride; 7(S)-Chloro-7-deoxylincomycin; 7-CDL; 7-Chloro-7-deoxylincomycin; 7-Chlorolincomycin; Antirobe; Chlolincocin; Cleocin; Clinimycin; Dalacine; Clindamycin Phosphate EP Impurity E. CAS No. 21462-39-5. Pack Sizes: 50 g. Product ID: B2693-300287. Molecular formula: C18H34Cl2N2O5S. Mole weight: 461.44. Custom synthesis is available. Send your inquiries for more information.
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Cy5-NHS ester
Cy5-NHS ester is a red-fluorescent probe that is reactive with primary amines on biomolecules such as proteins and nucleic acids. Group: Pharmaceutical. Alternative Names: Sulfo-Cyanine5, SE (ethyl);Cyanine 5, SE; 2-[5-[1-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-3H-indolium, Inner Salt. CAS No. 146368-14-1. Pack Sizes: 100 mg. Product ID: B2708-169282. Molecular formula: C37H43N3O10S2. Mole weight: 753.882. Custom synthesis is available. Send your inquiries for more information.
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CY7-SE triethylamine
CY7-SE Triethylamine is a fluorescence labeling agent (Ex = 700-770 nm, Em = 790 nm) used for labeling proteins, peptides, antibodies, and oligonucleotides. Group: Pharmaceutical. Alternative Names: Cy7-NHS ester triethylamine; 3H-Indolium, 2-[7-[1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-, inner salt, triethylamine; CY 7 NHS ester triethylamine; Cy 7.29.OSu triethylamine; N-Hydroxysuccinimidyl Cy7 triethylamine. Pack Sizes: 20 mg. Product ID: B1370-447393. Molecular formula: C45H60N4O10S2. Mole weight: 881.11. Custom synthesis is available. Send your inquiries for more information.
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Diroximel Fumarate
Diroximel Fumarate is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body. It reduces the progressive damage to nerve cells via activating the Nrf2 pathway. It also acts as a NF-kappa B inhibitor. Group: Pharmaceutical. Alternative Names: ALKS8700; ALKS 8700; ALKS-8700; 2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate; 1-[2-(2,5-Dioxo-1-pyrrolidinyl)ethyl] 4-methyl (2E)-2-butenedioate; 2-Butenedioic acid (2E)-, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester. CAS No. 1577222-14-0. Pack Sizes: 100 mg. Product ID: B0084-284754. Molecular formula: C11H13NO6. Mole weight: 255.22. Custom synthesis is available. Send your inquiries for more information.
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DM1-SPP
DM1 with a reactive linker SPP, which can react with antibody to make antibody drug conjugate, as a potent EGFR inhibitor and it overcomes resistant to EGFR. Group: Pharmaceutical. Alternative Names: N2'-deacetyl-N2'-[3-[[4-[(2,?5-dioxo-1-pyrrolidinyl)?oxy]?-1-methyl-4-oxobutyl]?dithio]?-1-oxopropyl]?-Maytansine; DM1 SPP. CAS No. 452072-20-7. Pack Sizes: 5 mg. Product ID: BADC-00010. Molecular formula: C44H59ClN4O14S2. Mole weight: 967.54. Custom synthesis is available. Send your inquiries for more information.
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DM4-SPDB
DM4 with a reactive linker SPDB, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site. Group: Pharmaceutical. Alternative Names: (1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-Chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10(26),11,13,16,18-pentaen-6-yl (2 S)-2-{[4-({4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl}disulfanyl)-4-methylpentanoyl](methyl)amino}propanoate (non-preferred name); DM4 SPDB. CAS No. 1626359-62-3. Pack Sizes: 1 mg. Product ID: BADC-00012. Molecular formula: C46H63ClN4O14S2. Mole weight: 995.59. Custom synthesis is available. Send your inquiries for more information.
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Dolastatin 10
Dolastatin 10 is a potent antimitotic peptide from a marine animal, strongly inhibiting microtubule assembly. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: DLS 10; NSC 376128; Dolastatin-10; DLS-10; DLS10; NSC376128; NSC-376128; L-Valinamide, N,N-dimethyl-L-valyl-N-[2-methoxy-4-[2-[1-methoxy-2-methyl-3-oxo-3-[[2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-(1-methylpropyl)-4-oxobutyl]-N-methyl-,[2S-[1[1R*(R*),2S*],2R*[1S*,2S*,3(R*)]]]-. CAS No. 110417-88-4. Pack Sizes: 5 mg. Product ID: BAT-010469. Molecular formula: C42H68N6O6S. Mole weight: 785.09. Custom synthesis is available. Send your inquiries for more information.
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Eliglustat hemitartrate
Eliglustat hemitartrate is a specific inhibitor of glucosylceramide synthase. It is under development as an oral substrate reduction therapy for Gaucher disease type 1 (GD1). It was developed by Genzyme Corp and has been listed by the FDA August 2014. Group: Pharmaceutical. Alternative Names: Genz-112638; Genz 112638; Genz112638; Eliglustat tartrate; Bis(N-((1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(pyrrolidin-1- ylmethyl)ethyl)octanamide) (2R,3R)-2,3-dihydroxybutanedioate; Octanamide, N-((1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1- pyrrolidinylmethyl)ethyl)-, (2R,3R)-2,3-dihydroxybutanedioate; N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide (2R,3R)-2,3-dihydroxybutanedioic acid. CAS No. 928659-70-5. Pack Sizes: 1 g. Product ID: B2693-474918. Molecular formula: C50H78N4O14. Mole weight: 959.17. Custom synthesis is available. Send your inquiries for more information.
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Fitusiran
Fitusiran, a small interfering RNA, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. It increases thrombin generation and has the potential for the research of the hemophilia. Group: Pharmaceutical. Alternative Names: ALN-AT3SC; SAR439774; RNA, ((2'-deoxy-2'-fluoro)G-sp-Gm-sp-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)A-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A),3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-Dgalactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)U-sp-Gm-(2'-deoxy2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Um-Gm-Gm-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)C-Cm-sp-Am-sp-Gm). CAS No. 1499251-18-1. Pack Sizes: 1 mg. Product ID: B1370-072729. Custom synthesis is available. Send your inquiries for more information.
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Futibatinib
Futibatinib is an orally bioavailable, selective and irreversible inhibitor of fibroblast growth factor receptors (FGFRs), displaying antineoplastic activity. It inhibits FGFR-mediated signal transduction and tumor cell proliferation. Group: Pharmaceutical. Alternative Names: 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1-pyrazolo[3,4-d]pyrimidinyl]-1-pyrrolidinyl]-2-propen-1-one; 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one. CAS No. 1448169-71-8. Pack Sizes: 250 mg. Product ID: B2693-292398. Molecular formula: C22H22N6O3. Mole weight: 418.45. Custom synthesis is available. Send your inquiries for more information.
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GalNac-L96 free base
GalNAC-L96 free base is a triantennary GalNAc ligand that can be used for the synthesis of GalNAC-SiRNA and for the delivery of nucleic acid drugs. GalNAc is a ligand for the asialal glycoprotein receptor (ASGPR). Group: Pharmaceutical. Alternative Names: L-96; Butanedioic acid, 1-[(3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] ester; 1-[(3R,5S)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[1,12,19,25-tetraoxo-14,14-bis[[3-oxo-3-[[3-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]propyl]amino]propoxy]methyl]-29-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-16-oxa-13,20,24-triazanonacos-1-yl]-3-pyrrolidinyl] butanedioate; GalNAc-L96-SA; L-96-Succinic Acid; GalNAc-L96-Succinate. CAS No. 1159408-61-3. Pack Sizes: 100 mg. Product ID: B1370-427872. Molecular formula: C121H179N11O45. Mole weight: 2507.76. Custom synthesis is available. Send your inquiries for more information.
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Givosiran sodium
Givosiran sodium is a small interfering RNA (siRNA) directed towards delta-aminolevulinate synthase 1 (ALAS1). Givosiran sodium has been indicated for the treatment of adults with acute hepatic porphyria (AHP). Group: Pharmaceutical. Alternative Names: ALN-AS1 sodium; ALN AS1 sodium; ALN-AS 1 sodium; WHO 10280 sodium; WHO-10280 sodium; WHO10280 sodium; Givlaari sodium; RNA, (Cm-sp-Am-sp-Gm-Am-Am-Am-(2'-deoxy-2'-fluoro)G-Am-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)C-Am-Um-Cm-Um-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)G-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)U-Cm-(2'-deoxy-2'-fluoro)U-Gm-sp-Gm-sp-Um) (1:1) sodium salt. Pack Sizes: 10 mg. Product ID: B1370-212888. Molecular formula: C524H651F16N173Na43O316P43S6. Mole weight: 17,245.56 Da. Custom synthesis is available. Send your inquiries for more information.
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IKK 16 hydrochloride
IKK 16 hydrochloride is a potent and selective IκB kinase (IKK) inhibitor with IC50s of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα, respectively. It inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells. Group: Pharmaceutical. Alternative Names: N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamide hydrochloride; [4-[(4-Benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone hydrochloride; Methanone, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-, hydrochloride (1:1). CAS No. 1186195-62-9. Pack Sizes: 50 mg. Product ID: B1370-470817. Molecular formula: C28H30ClN5OS. Mole weight: 520.09. Custom synthesis is available. Send your inquiries for more information.
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Inaxaplin
Inaxaplin is an apolipoprotein L1 (APOL1) function inhibitor. Group: Pharmaceutical. Alternative Names: 1H-Indole-3-propanamide, 5,7-difluoro-2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-. CAS No. 2446816-88-0. Pack Sizes: 100 mg. Product ID: B1370-373000. Molecular formula: C21H18F3N3O3. Mole weight: 417.38. Custom synthesis is available. Send your inquiries for more information.
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Inclisiran
Inclisiran is a medication approved for the treatment of people with atherosclerotic cardiovascular disease (ASCVD), ASCVD risk equivalents and heterozygous familial hypercholesterolemia (HeFH). It is a small interfering RNA (siRNA) that binds to PCSK9 messenger RNA, resulting in decreased concentrations of PCSK9 and plasma concentrations of LDL cholesterol. Group: Pharmaceutical. Alternative Names: ALN-PCSsc; ALN-60212; Leqvio; Inclisiran sodium; ALN-PCS; Leqvio; RNA, (Am-sp-(2'-deoxy-2'-fluoro)C-sp-Am-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)A-Am-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-Um-Am-Gm-sp-Am-sp-Am), complex with RNA (Cm-sp-Um-sp-Am-Gm-Am-Cm-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Um-dT-Um-Um-Gm-Cm-Um-Um-Um-Um-Gm-Um) 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate] (1:1). CAS No. 1639324-58-5. Pack Sizes: 5 mg. Product ID: B1370-057828. Molecular formula: C529H707F12N176O316P43S6. Mole weight: 16339.48. Custom synthesis is available. Send your inquiries for more information.
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Lasofoxifene tartrate
Lasofoxifene tartrate is the tartrate salt form of Lasofoxifene. Lasofoxifene is a third-generation selective estrogen receptor modulators (SERMs). Group: Pharmaceutical. Alternative Names: CP-336156; CP 336156; CP336156; (2R,3R)-2,3-dihydroxybutanedioic acid;(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol; LASOFOXIFENE HCL;(5R,6S)-5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol (2S,3S)-2,3-dihydrox. CAS No. 190791-29-8. Pack Sizes: 100 mg. Product ID: B0084-086542. Molecular formula: C28H31NO2.C4H6O6. Mole weight: 563.65. Custom synthesis is available. Send your inquiries for more information.
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Lincomycin
It is produced by the strain of Str. lincolnensis var. lincolnensis NRRL 2936. It's a sugar antibiotic. It has anti-gram-positive bacteria and spirochete effect, and has weak antibacterial effect on some gram-negative bacteria. It can protect mice infected with Staphylococcus aureus, Streptococcus hemolyticus and dicoccus pneumoniae by oral or subcutaneous injection. It also has effect on leptospira in vivo. Uses: Anti-bacterial agents. Group: Pharmaceutical. Alternative Names: (2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside; Lincocin; Lincogap; Clindamycin Phosphate EP Impurity A; Clindamycin hydrochloride EP Impurity A. CAS No. 154-21-2. Pack Sizes: 1mg;1g;10g. Product ID: BBF-02652. Molecular formula: C18H34N2O6S. Mole weight: 406.54. Custom synthesis is available. Send your inquiries for more information.
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Lincomycin 2-Phosphate
Lincomycin 2-Phosphate (Clindamycin Phosphate EP Impurity F) is an impurity of Clindamycin, which is a semi-synthetic antibiotic prepared from Lincomycin. Group: Pharmaceutical. Alternative Names: Lincomycin phosphate; Methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-Octopyranoside 2-(dihydrogen phosphate); Clindamycin Phosphate EP Impurity F. CAS No. 27480-30-4. Pack Sizes: 5 mg. Product ID: B2694-337341. Molecular formula: C18H35N2O9PS. Mole weight: 486.52. Custom synthesis is available. Send your inquiries for more information.
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Lincomycin hydrochloride
Lincomycin hydrochloride is produced by the strain of Str. lincolnensis var. lincolnensis NRRL 2936. It's a sugar antibiotic. It has anti-gram-positive bacteria and spirochete effect, and has weak antibacterial effect on some gram-negative bacteria. It can protect mice infected with Staphylococcus aureus, Streptococcus hemolyticus and dicoccus pneumoniae by oral or subcutaneous injection. It also has effect on leptospira in vivo. It can prevent and treat respiratory diseases, such as Haemophilus parasuis, infectious pleuropneumonia, mycoplasmosis, atrophic rhinitis, etc. Group: Pharmaceutical. Alternative Names: (2S-trans)-Methyl 6,8-Dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galactooctopyranoside Hydrochloride; trans-α-Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-D-erythro-D-galacto-Octopyranoside Monohydrochloride; Lincocin; Lincogap; NSC 70731; U 10149a. CAS No. 859-18-7. Pack Sizes: 1mg;1g;10g. Product ID: BBF-02653. Molecular formula: C18H35ClN2O6S. Mole weight: 443. Custom synthesis is available. Send your inquiries for more information.
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Lumasiran
Lumasiran is a siRNA product that reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1). Group: Pharmaceutical. Alternative Names: ALN-G01; RNA, (Gm-sp-Am-sp-Cm-Um-Um-Um-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)U-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Um-Gm-Gm-Am-Am-Am-Um-Am-Um-Am), 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]-1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2-pyrrolidinyl]methyl hydrogen phosphate], complex with RNA (Um-sp-(2'-deoxy-2'-fluoro)A-sp-Um-Am-Um-(2'-deoxy-2'-fluoro)U-Um-(2'-deoxy-2'-fluoro)C-(2'-deoxy-2'-fluoro)C-Am-Gm-Gm-Am-(2'-deoxy-2'-fluoro)U-Gm-(2'-deoxy-2'-fluoro)A-Am-Am-Gm-Um-Cm-sp-Cm-sp-Am) (1:1). CAS No. 1834610-13-7. Pack Sizes: 5 mg. Product ID: B1370-072716. Molecular formula: C530H712F10N173O320P43S6. Mole weight: 16,340 Da. Custom synthesis is available. Send your inquiries for more information.
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Mal-PEG2-NHS ester
Mal-PEG2-NHS ester is a non-cleavable ADC linker containing the Maleimide group, 2-unit PEG, and NHS ester. Group: Pharmaceutical. Alternative Names: 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2H-pyrrol-1(5H)-yl)ethoxy)ethoxy)propanoate; 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 1-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethyl]-1H-pyrrole-2,5-dione; 2,5-Dioxo-1-pyrrolidinyl 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]propanoate. CAS No. 1433997-01-3. Pack Sizes: 100 mg. Product ID: BADC-00453. Molecular formula: C15H18N2O8. Mole weight: 354.31. Custom synthesis is available. Send your inquiries for more information.
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Mc-MMAE
Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division. Group: Pharmaceutical. Alternative Names: Maleimidocaproyl-monomethylauristatin E; N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}- 3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide. CAS No. 863971-24-8. Pack Sizes: 1 mg. Product ID: BADC-00025. Molecular formula: C49H78N6O10. Mole weight: 911.18. Custom synthesis is available. Send your inquiries for more information.
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Meropenem Trihydrate
Meropenem Trihydrate is a carbapenem antibiotic, which has broad spectrum antibacterial activity. Group: Pharmaceutical. Alternative Names: [4R-[3(3S*,5S*),4α,5β,6β(R*)]]-3-[[5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Trihydrate; (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Trihydrate; SM-7338. CAS No. 119478-56-7. Pack Sizes: 100 mg. Product ID: BBF-04632. Molecular formula: C17H25N3O5S.3H2O. Mole weight: 437.51. Custom synthesis is available. Send your inquiries for more information.
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Mertansine
Mertansine, the cytotoxic component in antibody-drug conjugates, is attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker or SMCC (4-(3-mercapto-2,5-dioxo-1 pyrrolidinylmethyl)-cylohexanecarboxylic acid) linkerto create an antibody-drug conjugate. It derives from a maytansine. Group: Pharmaceutical. Alternative Names: (14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-(3-mercaptopropanoyl)-N-methyl-L-alaninate; N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine; DM 1; Maytansinoid DM 1; N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine; DM-1; DM1; DM1 Compound; DM1 [Maytansinoid]. CAS No. 139504-50-0. Pack Sizes: 40 mg(95%+). Product ID: BBF-05777. Molecular formula: C35H48ClN3O10S. Mole weight: 738.29. Custom synthesis is available. Send your inquiries for more information.
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MMAF
Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. Uses: Adcs cytotoxin. Group: Pharmaceutical. Alternative Names: Monomethylauristatin F; Monomethyl Auristatin F; N-Methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; Monomethylauristatin Phenylalanine; L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine. CAS No. 745017-94-1. Pack Sizes: 10 mg. Product ID: BBF-05779. Molecular formula: C39H65N5O8. Mole weight: 731.48. Custom synthesis is available. Send your inquiries for more information.
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Monodes(N-carboxymethyl)valine Daclatasvir
Monodes(N-carboxymethyl)valine Daclatasvir is an impurity of Daclatasvir, a medication that is effective against hepatitis C virus (HCV). Group: Pharmaceutical. Alternative Names: N-[(1S)-2-Methyl-1-[[(2S)-2-[5-[4'-[2-[(2S)-2-pyrrolidinyl]-1H-imidazol-5-yl][1,1'-biphenyl]-4-yl]-1H-imidazol-2-yl]-1-pyrrolidinyl]carbonyl]propyl]carbamic Acid Methyl Ester. CAS No. 1007884-60-7. Pack Sizes: 10 mg. Product ID: B2694-341915. Molecular formula: C33H39N7O3. Mole weight: 581.71. Custom synthesis is available. Send your inquiries for more information.
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N-(Chloroacetoxy)succinimide
N-(Chloroacetoxy)succinimide is a reagent used in the preparation of organometallic complexes and other synthetic probes for the labeling of proteins. Group: Pharmaceutical. Alternative Names: 1-[(chloroacetyl)oxy]pyrrolidine-2,5-dione; 2-chloro-Acetic acid 2,5-dioxo-1-pyrrolidinyl ester. CAS No. 27243-15-8. Pack Sizes: 5 g. Product ID: B2699-335082. Molecular formula: C6H6ClNO4. Mole weight: 191.57. Custom synthesis is available. Send your inquiries for more information.
Used in the preparation of lipophilic human glucagon-like peptide-1 derivatives with protracted action profiles. Group: Pharmaceutical. Alternative Names: Palm-glu(nhs)-otbu; L-Glutamic acid, N-(1-oxohexadecyl)-, 1-(1,1-dimethylethyl) 5-(2,5-dioxo-1-pyrrolidinyl) ester; (S)-1-tert-butyl 5-(2,5-dioxopyrrolidin-1-yl) 2-palmitamidopentanedioate; Pal-L-Glu(OSu)-OtBu; N-Palmitoyl-L-glutamic Acid 1-tert-Butyl 5-(N-Succinimidyl) Ester; 1-tert-Butyl 5-(2,5-dioxopyrrolidin-1-yl) N-hexadecanoyl-L-glutamate. CAS No. 204521-63-1. Pack Sizes: 5 g. Product ID: BAT-016678. Molecular formula: C29H50N2O7. Mole weight: 538.7. Custom synthesis is available. Send your inquiries for more information.
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N-SMP
N-SMP is a potent synthetic compound known for its efficacy against various neurological disorders. As a powerful inhibitor, this compound specifically targets key enzymes involved in the progression of these debilitating diseases. In addition, N-SMP is also widely used as a linker for antibody-drug conjugation. Group: Pharmaceutical. Alternative Names: 1-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-1H-pyrrole-2,5-dione; N-(α-Maleimidoacetoxy)succimide; AMAS; N-Succinimidyl maleimidoacetate; Maleimidoacetic Acid N-Succinimidyl Ester; N-(alpha-Maleimidoacetoxy)succinimide; a-Maleimidoacetic acid-NHS. CAS No. 55750-61-3. Pack Sizes: 5 g. Product ID: BAT-006479. Molecular formula: C10H8N2O6. Mole weight: 252.18. Custom synthesis is available. Send your inquiries for more information.
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NSP-DMAE-NHS
NSP-DMAE-NHS is an acridinium ester chemiluminescent reagent containing N-sulfopropyl groups. It is useful in the clinical diagnostic industry especially in automated immunochemical analyzers such as Siemens Healthcare Diagnostics' ADVIA Centaur systems. Group: Pharmaceutical. Alternative Names: 2',6'-Dimethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS Ester; 2',6'-Dimethyl-4'-(N-succinimidyloxycarbonyl) phenyl-10-sulfopropylacridinium-9-carboxylate; 9-[[4-[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,6-dimethylphenoxy]carbonyl]-10-(3-sulfopropyl)acridinium Inner Salt. CAS No. 194357-64-7. Pack Sizes: 5 mg. Product ID: B0245-172748. Molecular formula: C30H26N2O9S. Mole weight: 590.6. Custom synthesis is available. Send your inquiries for more information.
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NSP-SA-NHS
It is a direct chemiluminescent reagent, used to mark proteins, antigens, antibodies, nucleic acids (DNA, RNA), etc. Group: Pharmaceutical. Alternative Names: 3-[9-(((3-(N-succinimidyloxycarboxypropyl)[4-methxylphenyl]sulfonyl)amine)carboxyl]-10-acridiniumyl)-1-propanesulfonate; 3-(9-((4-((2,5-Dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)(tosyl)carbamoyl)acridin-10-ium-10-yl)propane-1-sulfonate; 9-[[[4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl][(4-methylphenyl)sulfonyl]amino]carbonyl]-10-(3-sulfopropyl)-acridinium inner salt. CAS No. 199293-83-9. Pack Sizes: 5 mg. Product ID: B0001-173202. Molecular formula: C32H31N3O10S2. Mole weight: 681.73. Custom synthesis is available. Send your inquiries for more information.
N-Succinimidyl 6-[[4-(maleimidomethyl)cyclohexyl]carboxamido] caproate. Uses: A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Group: Pharmaceutical. Alternative Names: 6-[[[4-[(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]amino]hexanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester; LC-SMCC. CAS No. 125559-00-4. Pack Sizes: 100 mg. Product ID: B1370-121728. Molecular formula: C22H29N3O7. Mole weight: 447.48. Custom synthesis is available. Send your inquiries for more information.
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Odorinol
Odorinol is isolated from the herbs of Aglaia odorata. It inhibits both the initiation and promotion stages of two-stage skin carcinogenesis. Group: Pharmaceutical. Alternative Names: Butanamide, 2-hydroxy-2-methyl-N-(1-(1-oxo-3-phenyl-2-propenyl)-2-pyrrolidinyl)-, (S-(R*,S*-(E)))-; (+)-Odorinol. CAS No. 72755-22-7. Pack Sizes: 1 mg. Product ID: NP0327. Molecular formula: C18H24N2O3. Mole weight: 316.4. Custom synthesis is available. Send your inquiries for more information.
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Piperlotine C
Piperlotine C is isolated from the herbs of Piper nigrum L. Group: Pharmaceutical. Alternative Names: 2-Propen-1-one, 1-(1-pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-, (2E). CAS No. 886989-88-4. Pack Sizes: 5 mg. Product ID: NP0143. Molecular formula: C16H21NO4. Mole weight: 291.4. Custom synthesis is available. Send your inquiries for more information.
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Piperlotine D
Piperlotine D is isolated from the herbs of Piper nigrum L. Uses: Antiplatelet aggregation. Group: Pharmaceutical. Alternative Names: (2Z)-1-(1-Pyrrolidinyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one. CAS No. 958296-13-4. Pack Sizes: 1 mg. Product ID: NP0176. Molecular formula: C16H21NO4. Mole weight: 291.4. Custom synthesis is available. Send your inquiries for more information.
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PSNCBAM-1
PSNCBAM-1 is an allosteric, non-competitive antagonist of CB-1 (IC50= 45 and 209 nM) with hypophagic effects in vivo, potentially an anti-obesity agents. Group: Pharmaceutical. Alternative Names: PSNCBAM 1; PSNCBAM1; N-(4-Chlorophenyl)-N'-(3-(6-(1-pyrrolidinyl)-2-pyridinyl)phenyl)urea. CAS No. 877202-74-9. Pack Sizes: 100 mg. Product ID: B1370-170068. Molecular formula: C22H21ClN4O. Mole weight: 392.88. Custom synthesis is available. Send your inquiries for more information.
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Quarfloxin
Quarfloxin, also known as Quarfloxacin and CX-3543, is a fluoroquinolone derivative with antineoplastic activity. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template, a critical interaction for rRNA biogenesis that is overexpressed in cancer cells. Disruption of this G-quadruplex DNA:protein interaction in aberrant rRNA biogenesis may result in the inhibition of ribosome synthesis and tumor cell apoptosis. Group: Pharmaceutical. Alternative Names: 3H-Benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide, 5-fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-[3-(2-pyrazinyl)-1-pyrrolidinyl]-; 3H-Benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide, 5-fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-(3-pyrazinyl-1-pyrrolidinyl)-; 5-Fluoro-N-[2-[(2S)-1-methyl-2-pyrrolidinyl]ethyl]-3-oxo-6-[3-(2-pyrazinyl)-1-pyrrolidinyl]-3H-benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide; CX 3543; Itarnafloxin; Quarfloxacin. CAS No. 865311-47-3. Pack Sizes: 5 mg. Product ID: B2693-153274. Molecular formula: C35H33FN6O3. Mole weight: 604.69. Custom synthesis is available. Send your inquiries for more information.
(R)-2-[[(tert-Butyldimethylsilyl)oxy]diphenylmethyl]pyrrolidine (CAS# 1236033-34-3 ) is a useful research chemical. Group: Pharmaceutical. Alternative Names: tert-butyl-[diphenyl-[(2R)-2-pyrrolidinyl]methoxy]-dimethylsilane; tert-butyl-[diphenyl-[(2R)-pyrrolidin-2-yl]methoxy]-dimethylsilane. CAS No. 1236033-34-3. Pack Sizes: 500 mg. Product ID: BB005729. Molecular formula: C23H33NOSi. Mole weight: 367.6. Custom synthesis is available. Send your inquiries for more information.
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Ramosetron Impurity 12
An impurity of Ramosetron.Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. Group: Pharmaceutical. Alternative Names: Pyrrolidin-1-yl(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-5-yl)methanone hydrochloride; pyrrolidin-1-yl(4,5,6,7-tetrahydro-3H-benzimidazol-5-yl)methanone; hydrochloride; VIQQUDRWPRGFBZ-UHFFFAOYSA-N; SCHEMBL9051125; DTXSID60597128; FD7376; (4,5,6,7-TETRAHYDRO-1H-BENZO[D]IMIDAZOL-5-YL)(PYRROLIDIN-1-YL)METHANONE HCL; FT-0709212; 5-pyrrolidinocarbonyl-4,5,6,7-tetrahydrobenzimidazole hydrochloride; N-[(4,5,6,7-tetrahydrobenzimidazol-5-yl)carbonyl]pyrrolidine hydrochloride; N-[(4,5,6,7-tetrahydrobenzimidazol-5-yl)carbonyl]pyrrolidinehydrochloride; Methanone, 1-pyrrolidinyl(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)-, hydrochloride (1:1); Pyrrolidin-1-yl(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-5-yl)methanonehydrochloride; (Pyrrolidin-1-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-6-yl)methanone--hydrogen chloride (1/1). CAS No. 132036-42-1. Pack Sizes: 50 mg. Product ID: B1803-083161. Molecular formula: C12H17N3O. Mole weight: 219.29. Custom synthesis is available. Send your inquiries for more information.
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Rocuronium bromide EP impurity F
An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Group: Pharmaceutical. Alternative Names: 2-Pyrrolidinyl-3-acetyl Desmorpholinylrocuronium Bromide; 1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-pyrrolidinyl)androstan-16-yl]-1-(2-propen-1-yl)-pyrrolidinium. CAS No. 1190105-66-8. Pack Sizes: 10 mg. Product ID: B2694-479224. Molecular formula: C34H55N2O4.Br. Mole weight: 635.72. Custom synthesis is available. Send your inquiries for more information.
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Rocuronium EP Impurity A
An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Group: Pharmaceutical. Alternative Names: 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol 17-Acetate; (2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol 17-Acetate; Desallyl Rocuronium. CAS No. 119302-24-8. Pack Sizes: 1 g. Product ID: B2694-055435. Molecular formula: C29H48N2O4. Mole weight: 488.72. Custom synthesis is available. Send your inquiries for more information.
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Rocuronium EP Impurity E
An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Group: Pharmaceutical. Alternative Names: 2-Pyrrolidinyl Desmorpholinylrocuronium Bromide; 1-[(2β,3α,5α,16β,17β)-17-(Acetyloxy)-3-hydroxy-2-(1-pyrrolidinyl)androstan-16-yl]-1-(2-propen-1-yl)-pyrrolidinium Bromide. CAS No. 1190105-65-7. Pack Sizes: 10 mg. Product ID: B2694-479221. Molecular formula: C32H53N2O3. Br. Mole weight: 593.69. Custom synthesis is available. Send your inquiries for more information.
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Rocuronium EP Impurity G
An impurity of Rocuronium. Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia to facilitate endotracheal intubation by providing skeletal muscle relaxation. Group: Pharmaceutical. Alternative Names: 2β-(4-Morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstane-3α,17β-diol; (2β,3α,5α,16β,17β)-2-(4-Morpholinyl)-16-(1-pyrrolidinyl)androstan-3,17-diol; Desacetyl Desallyl Rocuronium. CAS No. 119302-20-4. Pack Sizes: 250 mg. Product ID: B2694-394150. Molecular formula: C27H46N2O3. Mole weight: 446.68. Custom synthesis is available. Send your inquiries for more information.
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Semaglutide intermediate
Semaglutide intermediate is an intermediate of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Group: Pharmaceutical. Alternative Names: (S)-21,39-di-tert-butyl 1-(2,5-dioxopyrrolidin-1-yl) 9,18,23-trioxo-2,5,11,14-tetraoxa-8,17,22-triazanonatriacontane-1,21,39-tricarboxylate; 17-((S)-1-tert-Butoxycarbonyl-3-{2-[2-({2-[2-(2,5-dioxopyrrolidin-1-yloxycarbonylmethoxy)ethoxy]ethylcarbamoyl}methoxy)ethoxy]-ethylcarbamoyl}propylcarbamoyl)heptadecanoic acid tert-butyl ester; Octadecanoic acid, 18-[[(1S)-1-[(1,1-dimethylethoxy)carbonyl]-22-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4,13,22-trioxo-8,11,17,20-tetraoxa-5,14-diazadocos-1-yl]amino]-18-oxo-, 1,1-dimethylethyl ester; Bis(2-methyl-2-propanyl) (22S)-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazatetracontane-22,40-dicarboxylate; tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu. CAS No. 1118767-15-9. Pack Sizes: 5 g. Product ID: B2699-009884. Molecular formula: C47H82N4O15. Mole weight: 943.19. Custom synthesis is available. Send your inquiries for more information.
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SMCC
SMCC is a heterobifunctional protein crosslinker for antibody-drug-conjugation (ADC). Group: Pharmaceutical. Alternative Names: 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic Acid N-Hydroxysuccinimide Ester; NSC 344483; N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate; Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,5-dioxo-1-pyrrolidinyl ester; 1H-Pyrrole-2,5-dione, 1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-; 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate; 4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-ylmethyl)-cyclohexanecarboxylic acid 2,5-dioxo-pyrrolidin-1-yl ester; N-Hydroxysuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate; N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate; Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate; Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate; Succinimidyl 4-[maleimidomethyl]cyclohexan-1-carboxylate. CAS No. 64987-85-5. Pack Sizes: 5 g. Product ID: BAT-006461. Molecular formula: C16H18N2O6. Mole weight: 334.32. Custom synthesis is available. Send your inquiries for more information.
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TAK-448
TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints. Uses: Hypogonadism;prostate cancer. Group: Pharmaceutical. Alternative Names: MVT-602; Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2; RVT-602; RVT 602; TAK 448; RVT602; TAK448; N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-L-Tryptophanamide; Istaroxime; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide. CAS No. 1234319-68-6. Pack Sizes: 25 mg. Product ID: BAT-010642. Molecular formula: C58H80N16O14. Mole weight: 1225.36. Custom synthesis is available. Send your inquiries for more information.
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Teneligliptin HBr
Teneligliptin hydrobromide is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor. It competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro. Group: Pharmaceutical. Alternative Names: [(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl]-2-pyrrolidinyl]-3-thiazolidinylmethanone Hydrobromide (2:5); Teneligliptin Hydrobromide (2:5). CAS No. 906093-29-6. Pack Sizes: 250 mg. Product ID: B0084-463677. Molecular formula: C44H65Br5N12O2S2. Mole weight: 1257.72. Custom synthesis is available. Send your inquiries for more information.
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Trifarotene
Trifarotene is a retinoic acid receptor (RAR) agonist used as an agent for the treatment of acne. Uses: Dermatologic agents. Group: Pharmaceutical. Alternative Names: 3''-tert-Butyl-4'-(2-hydroxyethoxy)-4''-(pyrrolidin-1-yl)[1,1':3',1'']terphenyl-4-carboxylic Acid; 3''-(1,1-Dimethylethyl)-4'-(2-hydroxyethoxy)-4''-(1-pyrrolidinyl)[1,1':3',1''-terphenyl]-4-carboxylic Acid. CAS No. 895542-09-3. Pack Sizes: 5 mg. Product ID: B2693-343568. Molecular formula: C29H33NO4. Mole weight: 459.58. Custom synthesis is available. Send your inquiries for more information.
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Val-Cit-PAB-MMAE
Val-Cit-PAB-MMAE, a tubulin polymerase inhibitor, is a drug-linker conjugate for ADC. It contains an ADC linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE. Group: Pharmaceutical. Alternative Names: L-Valyl-N-{4-[(5S,8S,11S,12R)-11-[(2S)-2-butanyl]-12-(2-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-2-oxoethyl)-5,8-diisopropyl-4,10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N5-carbamoyl-L-ornithinamide. CAS No. 644981-35-1. Pack Sizes: 100 mg. Product ID: BBF-05881. Molecular formula: C58H94N10O12. Mole weight: 1123.43. Custom synthesis is available. Send your inquiries for more information.
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